1586287:BBK82 RS12465
gene id: 1586287:BBK82_RS12465
uniprot id: A0A1B2HGC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1586287:BBK82 RS13785
gene id: 1586287:BBK82_RS13785
uniprot id: A0A1B2HGZ1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1586287:BBK82 RS12040
gene id: 1586287:BBK82_RS12040
uniprot id: A0A1B2HG63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS04450
gene id: 1586287:BBK82_RS04450
uniprot id: A0A1B2HCI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1586287:BBK82 RS36525
gene id: 1586287:BBK82_RS36525
uniprot id: A0A1B2I036
names: Similarity
messages: Belongs to the YciI family.

1586287:BBK82 RS45395
gene id: 1586287:BBK82_RS45395
uniprot id: A0A1B2HWK5
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1586287:BBK82 RS23335
gene id: 1586287:BBK82_RS23335
uniprot id: A0A1B2HLG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1586287:BBK82 RS00715
gene id: 1586287:BBK82_RS00715
uniprot id: A0A1B2HAT4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1586287:BBK82 RS12155
gene id: 1586287:BBK82_RS12155
uniprot id: A0A1B2HG68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS17860
gene id: 1586287:BBK82_RS17860
uniprot id: A0A1B2HIU5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS12860
gene id: 1586287:BBK82_RS12860
uniprot id: A0A1B2HGH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1586287:BBK82 RS30535
gene id: 1586287:BBK82_RS30535
uniprot id: A0A1B2HPT6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1586287:BBK82 RS39855
gene id: 1586287:BBK82_RS39855
uniprot id: A0A1B2HU02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS16270
gene id: 1586287:BBK82_RS16270
uniprot id: A0A1B2HYH8
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1586287:BBK82 RS01675
gene id: 1586287:BBK82_RS01675
uniprot id: A0A1B2HB76
names: Similarity
messages: Belongs to the CutA family.

1586287:BBK82 RS36940
gene id: 1586287:BBK82_RS36940
uniprot id: A0A1B2HSQ7
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS21690
gene id: 1586287:BBK82_RS21690
uniprot id: A0A1B2HKP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1586287:BBK82 RS22855
gene id: 1586287:BBK82_RS22855
uniprot id: A0A1B2HL81
names: Similarity
messages: Belongs to the glutamine synthetase family.

1586287:BBK82 RS27660
gene id: 1586287:BBK82_RS27660
uniprot id: A0A1B2HNH5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS02415
gene id: 1586287:BBK82_RS02415
uniprot id: A0A1B2HBK7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS28560
gene id: 1586287:BBK82_RS28560
uniprot id: A0A1B2HNW0
names: Similarity
messages: Belongs to the citrate synthase family.

1586287:BBK82 RS02265
gene id: 1586287:BBK82_RS02265
uniprot id: A0A1B2HBG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS22280
gene id: 1586287:BBK82_RS22280
uniprot id: A0A1B2HKY9
names: Similarity
messages: Belongs to the UPF0098 family.

1586287:BBK82 RS40335
gene id: 1586287:BBK82_RS40335
uniprot id: A0A1B2HUE1
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS11790
gene id: 1586287:BBK82_RS11790
uniprot id: A0A1B2HG02
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS43640
gene id: 1586287:BBK82_RS43640
uniprot id: A0A1B2HVR0
names: Similarity
messages: Belongs to the EspG family.

1586287:BBK82 RS21465
gene id: 1586287:BBK82_RS21465
uniprot id: A0A1B2HKN3
names: Similarity
messages: Belongs to the YciI family.

1586287:BBK82 RS17625
gene id: 1586287:BBK82_RS17625
uniprot id: A0A1B2HIP9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1586287:BBK82 RS46670
gene id: 1586287:BBK82_RS46670
uniprot id: A0A1B2HX30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1586287:BBK82 RS10060
gene id: 1586287:BBK82_RS10060
uniprot id: A0A1B2HF79
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS03960
gene id: 1586287:BBK82_RS03960
uniprot id: A0A1B2HXQ0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1586287:BBK82 RS09650
gene id: 1586287:BBK82_RS09650
uniprot id: A0A1B2HY26
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1586287:BBK82 RS14750
gene id: 1586287:BBK82_RS14750
uniprot id: A0A1B2HHD2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

1586287:BBK82 RS02740
gene id: 1586287:BBK82_RS02740
uniprot id: A0A1B2HBP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1586287:BBK82 RS02355
gene id: 1586287:BBK82_RS02355
uniprot id: A0A1B2HBJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1586287:BBK82 RS31110
gene id: 1586287:BBK82_RS31110
uniprot id: A0A1B2HQ56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS16235
gene id: 1586287:BBK82_RS16235
uniprot id: A0A1B2HI58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1586287:BBK82 RS07110
gene id: 1586287:BBK82_RS07110
uniprot id: A0A1B2HDS9
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS22175
gene id: 1586287:BBK82_RS22175
uniprot id: A0A1B2HKY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS26090
gene id: 1586287:BBK82_RS26090
uniprot id: A0A1B2HMS5
names: Similarity
messages: Belongs to the thioredoxin family.

1586287:BBK82 RS32080
gene id: 1586287:BBK82_RS32080
uniprot id: A0A1B2HQI4
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1586287:BBK82 RS08135
gene id: 1586287:BBK82_RS08135
uniprot id: A0A1B2HEA5
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS35305
gene id: 1586287:BBK82_RS35305
uniprot id: A0A1B2HS32
names: Similarity
messages: Belongs to the YciI family.

1586287:BBK82 RS15145
gene id: 1586287:BBK82_RS15145
uniprot id: A0A1B2HHJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS09305
gene id: 1586287:BBK82_RS09305
uniprot id: A0A1B2HY00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1586287:BBK82 RS29510
gene id: 1586287:BBK82_RS29510
uniprot id: A0A1B2HZK1
names: Similarity
messages: Belongs to the group II decarboxylase family.

1586287:BBK82 RS21260
gene id: 1586287:BBK82_RS21260
uniprot id: A0A1B2HKH3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1586287:BBK82 RS33690
gene id: 1586287:BBK82_RS33690
uniprot id: A0A1B2HRB5
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS33825
gene id: 1586287:BBK82_RS33825
uniprot id: A0A1B2HRD8
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1586287:BBK82 RS31235
gene id: 1586287:BBK82_RS31235
uniprot id: A0A1B2HQ44
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1586287:BBK82 RS46905
gene id: 1586287:BBK82_RS46905
uniprot id: A0A1B2I0U3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1586287:BBK82 RS09755
gene id: 1586287:BBK82_RS09755
uniprot id: A0A1B2HF10
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS04075
gene id: 1586287:BBK82_RS04075
uniprot id: A0A1B2HCD8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1586287:BBK82 RS19290
gene id: 1586287:BBK82_RS19290
uniprot id: A0A1B2HJJ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1586287:BBK82 RS06675
gene id: 1586287:BBK82_RS06675
uniprot id: A0A1B2HDL1
names: Similarity
messages: Belongs to the creatininase superfamily.

1586287:BBK82 RS16855
gene id: 1586287:BBK82_RS16855
uniprot id: A0A1B2HIC4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1586287:BBK82 RS39450
gene id: 1586287:BBK82_RS39450
uniprot id: A0A1B2HTU8
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

1586287:BBK82 RS53910
gene id: 1586287:BBK82_RS53910
uniprot id: A0A1B2HF02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1586287:BBK82 RS09980
gene id: 1586287:BBK82_RS09980
uniprot id: A0A1B2HF42
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

1586287:BBK82 RS34540
gene id: 1586287:BBK82_RS34540
uniprot id: A0A1B2HRS6
names: Similarity
messages: Belongs to the terpene synthase family.

1586287:BBK82 RS29395
gene id: 1586287:BBK82_RS29395
uniprot id: A0A1B2HPA2
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS21710
gene id: 1586287:BBK82_RS21710
uniprot id: A0A1B2HKR9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1586287:BBK82 RS37995
gene id: 1586287:BBK82_RS37995
uniprot id: A0A1B2HT54
names: Similarity
messages: Belongs to the peptidase S8 family.

1586287:BBK82 RS21130
gene id: 1586287:BBK82_RS21130
uniprot id: A0A1B2HKH2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1586287:BBK82 RS28210
gene id: 1586287:BBK82_RS28210
uniprot id: A0A1B2HNR8
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1586287:BBK82 RS15345
gene id: 1586287:BBK82_RS15345
uniprot id: A0A1B2HHM8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1586287:BBK82 RS45530
gene id: 1586287:BBK82_RS45530
uniprot id: A0A1B2HWR7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS20010
gene id: 1586287:BBK82_RS20010
uniprot id: A0A1B2HJV6
names: Similarity
messages: Belongs to the peptidase M1 family.

1586287:BBK82 RS07920
gene id: 1586287:BBK82_RS07920
uniprot id: A0A1B2HE43
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1586287:BBK82 RS05485
gene id: 1586287:BBK82_RS05485
uniprot id: A0A1B2HD17
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1586287:BBK82 RS40850
gene id: 1586287:BBK82_RS40850
uniprot id: A0A1B2HUI8
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1586287:BBK82 RS06155
gene id: 1586287:BBK82_RS06155
uniprot id: A0A1B2HDE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1586287:BBK82 RS12920
gene id: 1586287:BBK82_RS12920
uniprot id: A0A1B2HGJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

1586287:BBK82 RS33890
gene id: 1586287:BBK82_RS33890
uniprot id: A0A1B2HRG3
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1586287:BBK82 RS20560
gene id: 1586287:BBK82_RS20560
uniprot id: A0A1B2HK59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1586287:BBK82 RS04360
gene id: 1586287:BBK82_RS04360
uniprot id: A0A1B2HCH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1586287:BBK82 RS08665
gene id: 1586287:BBK82_RS08665
uniprot id: A0A1B2HEJ2
names: Similarity
messages: Belongs to the LppX/LprAFG lipoprotein family.

1586287:BBK82 RS01415
gene id: 1586287:BBK82_RS01415
uniprot id: A0A1B2HB34
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS12185
gene id: 1586287:BBK82_RS12185
uniprot id: A0A1B2HG67
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1586287:BBK82 RS02480
gene id: 1586287:BBK82_RS02480
uniprot id: A0A1B2HBL8
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1586287:BBK82 RS08410
gene id: 1586287:BBK82_RS08410
uniprot id: A0A1B2HEE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1586287:BBK82 RS19110
gene id: 1586287:BBK82_RS19110
uniprot id: A0A1B2HJG8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1586287:BBK82 RS17855
gene id: 1586287:BBK82_RS17855
uniprot id: A0A1B2HIU8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1586287:BBK82 RS20275
gene id: 1586287:BBK82_RS20275
uniprot id: A0A1B2HJZ1
names: Similarity
messages: Belongs to the TPP enzyme family.

1586287:BBK82 RS01310
gene id: 1586287:BBK82_RS01310
uniprot id: A0A1B2HB09
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS37090
gene id: 1586287:BBK82_RS37090
uniprot id: A0A1B2HSQ6
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS06070
gene id: 1586287:BBK82_RS06070
uniprot id: A0A1B2HD93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS12035
gene id: 1586287:BBK82_RS12035
uniprot id: A0A1B2HG21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS18055
gene id: 1586287:BBK82_RS18055
uniprot id: A0A1B2HIY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1586287:BBK82 RS14560
gene id: 1586287:BBK82_RS14560
uniprot id: A0A1B2HHA2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1586287:BBK82 RS11745
gene id: 1586287:BBK82_RS11745
uniprot id: A0A1B2HFX4
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

1586287:BBK82 RS15840
gene id: 1586287:BBK82_RS15840
uniprot id: A0A1B2HHX2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS21235
gene id: 1586287:BBK82_RS21235
uniprot id: A0A1B2HKJ2
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1586287:BBK82 RS26895
gene id: 1586287:BBK82_RS26895
uniprot id: A0A1B2HZB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1586287:BBK82 RS20800
gene id: 1586287:BBK82_RS20800
uniprot id: A0A1B2HK88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

1586287:BBK82 RS28020
gene id: 1586287:BBK82_RS28020
uniprot id: A0A1B2HNM2
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1586287:BBK82 RS52940
gene id: 1586287:BBK82_RS52940
uniprot id: A0A1B2HQD8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS22560
gene id: 1586287:BBK82_RS22560
uniprot id: A0A1B2HL34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1586287:BBK82 RS03800
gene id: 1586287:BBK82_RS03800
uniprot id: A0A1B2HC89
names: Similarity
messages: Belongs to the serpin family.

1586287:BBK82 RS20750
gene id: 1586287:BBK82_RS20750
uniprot id: A0A1B2HK87
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1586287:BBK82 RS09950
gene id: 1586287:BBK82_RS09950
uniprot id: A0A1B2HF17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS13720
gene id: 1586287:BBK82_RS13720
uniprot id: A0A1B2HGX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS23670
gene id: 1586287:BBK82_RS23670
uniprot id: A0A1B2HLN6
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1586287:BBK82 RS22605
gene id: 1586287:BBK82_RS22605
uniprot id: A0A1B2HL35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1586287:BBK82 RS05460
gene id: 1586287:BBK82_RS05460
uniprot id: A0A1B2HD28
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1586287:BBK82 RS09365
gene id: 1586287:BBK82_RS09365
uniprot id: A0A1B2HET3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS24985
gene id: 1586287:BBK82_RS24985
uniprot id: A0A1B2HMA2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS29545
gene id: 1586287:BBK82_RS29545
uniprot id: A0A1B2HPE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1586287:BBK82 RS29535
gene id: 1586287:BBK82_RS29535
uniprot id: A0A1B2HPF0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS31530
gene id: 1586287:BBK82_RS31530
uniprot id: A0A1B2HQ99
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS42635
gene id: 1586287:BBK82_RS42635
uniprot id: A0A1B2HV91
names: Similarity
messages: Belongs to the asparagine synthetase family.

1586287:BBK82 RS28455
gene id: 1586287:BBK82_RS28455
uniprot id: A0A1B2HNW6
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1586287:BBK82 RS06385
gene id: 1586287:BBK82_RS06385
uniprot id: A0A1B2HDL0
names: Similarity
messages: Belongs to the asparaginase 1 family.

1586287:BBK82 RS17100
gene id: 1586287:BBK82_RS17100
uniprot id: A0A1B2HIF4
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1586287:BBK82 RS33040
gene id: 1586287:BBK82_RS33040
uniprot id: A0A1B2HR31
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1586287:BBK82 RS26400
gene id: 1586287:BBK82_RS26400
uniprot id: A0A1B2HZA3
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS21435
gene id: 1586287:BBK82_RS21435
uniprot id: A0A1B2HKJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1586287:BBK82 RS17605
gene id: 1586287:BBK82_RS17605
uniprot id: A0A1B2HIP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1586287:BBK82 RS11525
gene id: 1586287:BBK82_RS11525
uniprot id: A0A1B2HFV5
names: Subunit
messages: Homodimer.

1586287:BBK82 RS12145
gene id: 1586287:BBK82_RS12145
uniprot id: A0A1B2HG70
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1586287:BBK82 RS19195
gene id: 1586287:BBK82_RS19195
uniprot id: A0A1B2HJI3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1586287:BBK82 RS06425
gene id: 1586287:BBK82_RS06425
uniprot id: A0A1B2HDJ0
names: Subcellular Location Annotation
messages: Cytoplasm

1586287:BBK82 RS24540
gene id: 1586287:BBK82_RS24540
uniprot id: A0A1B2HM37
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1586287:BBK82 RS00170
gene id: 1586287:BBK82_RS00170
uniprot id: A0A1B2HAI2
names: Similarity
messages: Belongs to the TrpF family.

1586287:BBK82 RS01565
gene id: 1586287:BBK82_RS01565
uniprot id: A0A1B2HB72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-binding monooxygenase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

1586287:BBK82 RS36125
gene id: 1586287:BBK82_RS36125
uniprot id: A0A1B2HS99
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS10475
gene id: 1586287:BBK82_RS10475
uniprot id: A0A1B2HFD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1586287:BBK82 RS43845
gene id: 1586287:BBK82_RS43845
uniprot id: A0A1B2HVT9
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.

1586287:BBK82 RS15895
gene id: 1586287:BBK82_RS15895
uniprot id: A0A1B2HHY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1586287:BBK82 RS42235
gene id: 1586287:BBK82_RS42235
uniprot id: A0A1B2HV60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS09575
gene id: 1586287:BBK82_RS09575
uniprot id: A0A1B2HEY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1586287:BBK82 RS14805
gene id: 1586287:BBK82_RS14805
uniprot id: A0A1B2HHE5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS22995
gene id: 1586287:BBK82_RS22995
uniprot id: A0A1B2HYY4
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1586287:BBK82 RS19895
gene id: 1586287:BBK82_RS19895
uniprot id: A0A1B2HJW2
names: Similarity
messages: Belongs to the CFA/CMAS family.

1586287:BBK82 RS33230
gene id: 1586287:BBK82_RS33230
uniprot id: A0A1B2HR19
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1586287:BBK82 RS04630
gene id: 1586287:BBK82_RS04630
uniprot id: A0A1B2HCN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1586287:BBK82 RS17410
gene id: 1586287:BBK82_RS17410
uniprot id: A0A1B2HIL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1586287:BBK82 RS22740
gene id: 1586287:BBK82_RS22740
uniprot id: A0A1B2HL78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.
messages: Membrane

1586287:BBK82 RS23160
gene id: 1586287:BBK82_RS23160
uniprot id: A0A1B2HLE3
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS10075
gene id: 1586287:BBK82_RS10075
uniprot id: A0A1B2HF28
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1586287:BBK82 RS39835
gene id: 1586287:BBK82_RS39835
uniprot id: A0A1B2HU05
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1586287:BBK82 RS20350
gene id: 1586287:BBK82_RS20350
uniprot id: A0A1B2HK23
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1586287:BBK82 RS04780
gene id: 1586287:BBK82_RS04780
uniprot id: A0A1B2HCT9
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

1586287:BBK82 RS23015
gene id: 1586287:BBK82_RS23015
uniprot id: A0A1B2HLA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

1586287:BBK82 RS16850
gene id: 1586287:BBK82_RS16850
uniprot id: A0A1B2HIC9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1586287:BBK82 RS01895
gene id: 1586287:BBK82_RS01895
uniprot id: A0A1B2HBA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS17015
gene id: 1586287:BBK82_RS17015
uniprot id: A0A1B2HIE5
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS06410
gene id: 1586287:BBK82_RS06410
uniprot id: A0A1B2HDF9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

1586287:BBK82 RS05930
gene id: 1586287:BBK82_RS05930
uniprot id: A0A1B2HD73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS01655
gene id: 1586287:BBK82_RS01655
uniprot id: A0A1B2HB71
names: Similarity
messages: Belongs to the peptidase S9C family.

1586287:BBK82 RS40960
gene id: 1586287:BBK82_RS40960
uniprot id: A0A1B2HUH1
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1586287:BBK82 RS23885
gene id: 1586287:BBK82_RS23885
uniprot id: A0A1B2HLP9
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS08045
gene id: 1586287:BBK82_RS08045
uniprot id: A0A1B2HXW7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS09780
gene id: 1586287:BBK82_RS09780
uniprot id: A0A1B2HY01
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1586287:BBK82 RS19625
gene id: 1586287:BBK82_RS19625
uniprot id: A0A1B2HJM9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

1586287:BBK82 RS02945
gene id: 1586287:BBK82_RS02945
uniprot id: A0A1B2HBU8
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1586287:BBK82 RS45850
gene id: 1586287:BBK82_RS45850
uniprot id: A0A1B2HWU7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1586287:BBK82 RS21370
gene id: 1586287:BBK82_RS21370
uniprot id: A0A1B2HKJ0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1586287:BBK82 RS12590
gene id: 1586287:BBK82_RS12590
uniprot id: A0A1B2HGD6
names: Similarity
messages: Belongs to the peptidase S13 family.

1586287:BBK82 RS11250
gene id: 1586287:BBK82_RS11250
uniprot id: A0A1B2HFQ5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1586287:BBK82 RS04675
gene id: 1586287:BBK82_RS04675
uniprot id: A0A1B2HCN0
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1586287:BBK82 RS43585
gene id: 1586287:BBK82_RS43585
uniprot id: A0A1B2HVT8
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1586287:BBK82 RS36515
gene id: 1586287:BBK82_RS36515
uniprot id: A0A1B2HSI0
names: Similarity
messages: Belongs to the peptidase S8 family.

1586287:BBK82 RS10995
gene id: 1586287:BBK82_RS10995
uniprot id: A0A1B2HFL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1586287:BBK82 RS21065
gene id: 1586287:BBK82_RS21065
uniprot id: A0A1B2HKE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1586287:BBK82 RS06115
gene id: 1586287:BBK82_RS06115
uniprot id: A0A1B2HDB5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1586287:BBK82 RS02910
gene id: 1586287:BBK82_RS02910
uniprot id: A0A1B2HXI7
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1586287:BBK82 RS25815
gene id: 1586287:BBK82_RS25815
uniprot id: A0A1B2HMN3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1586287:BBK82 RS41230
gene id: 1586287:BBK82_RS41230
uniprot id: A0A1B2HUQ7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1586287:BBK82 RS35440
gene id: 1586287:BBK82_RS35440
uniprot id: A0A1B2HS18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

1586287:BBK82 RS17610
gene id: 1586287:BBK82_RS17610
uniprot id: A0A1B2HIQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1586287:BBK82 RS24095
gene id: 1586287:BBK82_RS24095
uniprot id: A0A1B2HLT6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1586287:BBK82 RS20180
gene id: 1586287:BBK82_RS20180
uniprot id: A0A1B2HK19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1586287:BBK82 RS34545
gene id: 1586287:BBK82_RS34545
uniprot id: A0A1B2HRK7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1586287:BBK82 RS19610
gene id: 1586287:BBK82_RS19610
uniprot id: A0A1B2HJM3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS14330
gene id: 1586287:BBK82_RS14330
uniprot id: A0A1B2HH85
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1586287:BBK82 RS23690
gene id: 1586287:BBK82_RS23690
uniprot id: A0A1B2HLN0
names: Similarity
messages: In the C-terminal section; belongs to the anthranilate synthase component I family.

1586287:BBK82 RS45475
gene id: 1586287:BBK82_RS45475
uniprot id: A0A1B2HWQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1586287:BBK82 RS09920
gene id: 1586287:BBK82_RS09920
uniprot id: A0A1B2HF50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1586287:BBK82 RS36805
gene id: 1586287:BBK82_RS36805
uniprot id: A0A1B2HSQ1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS19000
gene id: 1586287:BBK82_RS19000
uniprot id: A0A1B2HYT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1586287:BBK82 RS22825
gene id: 1586287:BBK82_RS22825
uniprot id: A0A1B2HL92
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS19590
gene id: 1586287:BBK82_RS19590
uniprot id: A0A1B2HJQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS22835
gene id: 1586287:BBK82_RS22835
uniprot id: A0A1B2HL95
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS18150
gene id: 1586287:BBK82_RS18150
uniprot id: A0A1B2HJ01
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1586287:BBK82 RS45235
gene id: 1586287:BBK82_RS45235
uniprot id: A0A1B2I0T5
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

1586287:BBK82 RS17170
gene id: 1586287:BBK82_RS17170
uniprot id: A0A1B2HIH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1586287:BBK82 RS46165
gene id: 1586287:BBK82_RS46165
uniprot id: A0A1B2HWX3
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS35260
gene id: 1586287:BBK82_RS35260
uniprot id: A0A1B2HRZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1586287:BBK82 RS18640
gene id: 1586287:BBK82_RS18640
uniprot id: A0A1B2HJ75
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS44980
gene id: 1586287:BBK82_RS44980
uniprot id: A0A1B2HWB5
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS17660
gene id: 1586287:BBK82_RS17660
uniprot id: A0A1B2HYL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1586287:BBK82 RS23255
gene id: 1586287:BBK82_RS23255
uniprot id: A0A1B2HLE4
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

1586287:BBK82 RS45095
gene id: 1586287:BBK82_RS45095
uniprot id: A0A1B2HWF5
names: Similarity
messages: Belongs to the peptidase M24B family.

1586287:BBK82 RS22580
gene id: 1586287:BBK82_RS22580
uniprot id: A0A1B2HL29
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS23070
gene id: 1586287:BBK82_RS23070
uniprot id: A0A1B2HLB0
names: Similarity
messages: Belongs to the peptidase M28 family. M28A subfamily.

1586287:BBK82 RS41770
gene id: 1586287:BBK82_RS41770
uniprot id: A0A1B2I0J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1586287:BBK82 RS43560
gene id: 1586287:BBK82_RS43560
uniprot id: A0A1B2I0P5
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1586287:BBK82 RS01900
gene id: 1586287:BBK82_RS01900
uniprot id: A0A1B2HBA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS06415
gene id: 1586287:BBK82_RS06415
uniprot id: A0A1B2HDH1
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

1586287:BBK82 RS42105
gene id: 1586287:BBK82_RS42105
uniprot id: A0A1B2I0I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1586287:BBK82 RS31695
gene id: 1586287:BBK82_RS31695
uniprot id: A0A1B2HQC9
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS40165
gene id: 1586287:BBK82_RS40165
uniprot id: A0A1B2HU58
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS04000
gene id: 1586287:BBK82_RS04000
uniprot id: A0A1B2HCC3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1586287:BBK82 RS27055
gene id: 1586287:BBK82_RS27055
uniprot id: A0A1B2HN81
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS36425
gene id: 1586287:BBK82_RS36425
uniprot id: A0A1B2HSI2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS34400
gene id: 1586287:BBK82_RS34400
uniprot id: A0A1B2HZW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS10380
gene id: 1586287:BBK82_RS10380
uniprot id: A0A1B2HFA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1586287:BBK82 RS30555
gene id: 1586287:BBK82_RS30555
uniprot id: A0A1B2HPU5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1586287:BBK82 RS33950
gene id: 1586287:BBK82_RS33950
uniprot id: A0A1B2HRI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS18670
gene id: 1586287:BBK82_RS18670
uniprot id: A0A1B2HJ87
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1586287:BBK82 RS46215
gene id: 1586287:BBK82_RS46215
uniprot id: A0A1B2HWX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1586287:BBK82 RS09475
gene id: 1586287:BBK82_RS09475
uniprot id: A0A1B2HEW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1586287:BBK82 RS35535
gene id: 1586287:BBK82_RS35535
uniprot id: A0A1B2HS60
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS14250
gene id: 1586287:BBK82_RS14250
uniprot id: A0A1B2HH75
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS05615
gene id: 1586287:BBK82_RS05615
uniprot id: A0A1B2HD51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

1586287:BBK82 RS25040
gene id: 1586287:BBK82_RS25040
uniprot id: A0A1B2HMB9
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS32180
gene id: 1586287:BBK82_RS32180
uniprot id: A0A1B2HQK7
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

1586287:BBK82 RS12825
gene id: 1586287:BBK82_RS12825
uniprot id: A0A1B2HYA7
names: Caution
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS18175
gene id: 1586287:BBK82_RS18175
uniprot id: A0A1B2HIZ9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1586287:BBK82 RS28605
gene id: 1586287:BBK82_RS28605
uniprot id: A0A1B2HNX9
names: Similarity
messages: Belongs to the UPF0303 family.

1586287:BBK82 RS07835
gene id: 1586287:BBK82_RS07835
uniprot id: A0A1B2HE32
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1586287:BBK82 RS41820
gene id: 1586287:BBK82_RS41820
uniprot id: A0A1B2HV22
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1586287:BBK82 RS20290
gene id: 1586287:BBK82_RS20290
uniprot id: A0A1B2HK13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1586287:BBK82 RS17680
gene id: 1586287:BBK82_RS17680
uniprot id: A0A1B2HIP7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1586287:BBK82 RS22015
gene id: 1586287:BBK82_RS22015
uniprot id: A0A1B2HKV2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1586287:BBK82 RS45220
gene id: 1586287:BBK82_RS45220
uniprot id: A0A1B2HWG5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1586287:BBK82 RS17385
gene id: 1586287:BBK82_RS17385
uniprot id: A0A1B2HIK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1586287:BBK82 RS17565
gene id: 1586287:BBK82_RS17565
uniprot id: A0A1B2HIP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1586287:BBK82 RS20920
gene id: 1586287:BBK82_RS20920
uniprot id: A0A1B2HKA3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1586287:BBK82 RS09550
gene id: 1586287:BBK82_RS09550
uniprot id: A0A1B2HY43
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1586287:BBK82 RS45140
gene id: 1586287:BBK82_RS45140
uniprot id: A0A1B2HWE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1586287:BBK82 RS32840
gene id: 1586287:BBK82_RS32840
uniprot id: A0A1B2HQV8
names: Similarity
messages: Belongs to the NodU/CmcH family.

1586287:BBK82 RS38660
gene id: 1586287:BBK82_RS38660
uniprot id: A0A1B2HTK5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1586287:BBK82 RS34505
gene id: 1586287:BBK82_RS34505
uniprot id: A0A1B2HRQ4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS28195
gene id: 1586287:BBK82_RS28195
uniprot id: A0A1B2HNQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS17280
gene id: 1586287:BBK82_RS17280
uniprot id: A0A1B2HIJ5
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1586287:BBK82 RS25005
gene id: 1586287:BBK82_RS25005
uniprot id: A0A1B2HM90
names: Similarity
messages: Belongs to the type IB topoisomerase family.

1586287:BBK82 RS08880
gene id: 1586287:BBK82_RS08880
uniprot id: A0A1B2HEL8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1586287:BBK82 RS35425
gene id: 1586287:BBK82_RS35425
uniprot id: A0A1B2HS08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

1586287:BBK82 RS20555
gene id: 1586287:BBK82_RS20555
uniprot id: A0A1B2HK37
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1586287:BBK82 RS39230
gene id: 1586287:BBK82_RS39230
uniprot id: A0A1B2HTR3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1586287:BBK82 RS20420
gene id: 1586287:BBK82_RS20420
uniprot id: A0A1B2HK31
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

1586287:BBK82 RS12350
gene id: 1586287:BBK82_RS12350
uniprot id: A0A1B2HG98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS21240
gene id: 1586287:BBK82_RS21240
uniprot id: A0A1B2HKH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1586287:BBK82 RS23090
gene id: 1586287:BBK82_RS23090
uniprot id: A0A1B2HZ29
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1586287:BBK82 RS28495
gene id: 1586287:BBK82_RS28495
uniprot id: A0A1B2HZC2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Heterodimer of an alpha and a beta chain.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS27075
gene id: 1586287:BBK82_RS27075
uniprot id: A0A1B2HNB9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1586287:BBK82 RS26170
gene id: 1586287:BBK82_RS26170
uniprot id: A0A1B2HMV0
names: Similarity
messages: Belongs to the CobH/CbiC family.

1586287:BBK82 RS29145
gene id: 1586287:BBK82_RS29145
uniprot id: A0A1B2HP77
names: Similarity
messages: Belongs to the proline racemase family.

1586287:BBK82 RS17815
gene id: 1586287:BBK82_RS17815
uniprot id: A0A1B2HIT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1586287:BBK82 RS26020
gene id: 1586287:BBK82_RS26020
uniprot id: A0A1B2HMR3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS40080
gene id: 1586287:BBK82_RS40080
uniprot id: A0A1B2I0E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1586287:BBK82 RS11610
gene id: 1586287:BBK82_RS11610
uniprot id: A0A1B2HFY2
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1586287:BBK82 RS09860
gene id: 1586287:BBK82_RS09860
uniprot id: A0A1B2HF39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1586287:BBK82 RS46445
gene id: 1586287:BBK82_RS46445
uniprot id: A0A1B2HX10
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS21895
gene id: 1586287:BBK82_RS21895
uniprot id: A0A1B2HKS4
names: Function
names: Similarity
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

1586287:BBK82 RS04225
gene id: 1586287:BBK82_RS04225
uniprot id: A0A1B2HCG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1586287:BBK82 RS01695
gene id: 1586287:BBK82_RS01695
uniprot id: A0A1B2HB80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1586287:BBK82 RS12270
gene id: 1586287:BBK82_RS12270
uniprot id: A0A1B2HGA1
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1586287:BBK82 RS16015
gene id: 1586287:BBK82_RS16015
uniprot id: A0A1B2HI06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1586287:BBK82 RS12560
gene id: 1586287:BBK82_RS12560
uniprot id: A0A1B2HGD4
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1586287:BBK82 RS11890
gene id: 1586287:BBK82_RS11890
uniprot id: A0A1B2HG05
names: Similarity
messages: Belongs to the AAA ATPase family.

1586287:BBK82 RS31970
gene id: 1586287:BBK82_RS31970
uniprot id: A0A1B2HZN6
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

1586287:BBK82 RS46740
gene id: 1586287:BBK82_RS46740
uniprot id: A0A1B2HX73
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1586287:BBK82 RS33470
gene id: 1586287:BBK82_RS33470
uniprot id: A0A1B2HR50
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS19215
gene id: 1586287:BBK82_RS19215
uniprot id: A0A1B2HYU1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1586287:BBK82 RS05450
gene id: 1586287:BBK82_RS05450
uniprot id: A0A1B2HCZ5
names: Similarity
messages: Belongs to the mycobacterial PPE family.

1586287:BBK82 RS35860
gene id: 1586287:BBK82_RS35860
uniprot id: A0A1B2HS81
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1586287:BBK82 RS34680
gene id: 1586287:BBK82_RS34680
uniprot id: A0A1B2HRS2
names: Subcellular Location Annotation
messages: Cytoplasm

1586287:BBK82 RS20550
gene id: 1586287:BBK82_RS20550
uniprot id: A0A1B2HK47
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1586287:BBK82 RS12385
gene id: 1586287:BBK82_RS12385
uniprot id: A0A1B2HY90
names: Similarity
messages: Belongs to the Nth/MutY family.

1586287:BBK82 RS42265
gene id: 1586287:BBK82_RS42265
uniprot id: A0A1B2HV72
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1586287:BBK82 RS15790
gene id: 1586287:BBK82_RS15790
uniprot id: A0A1B2HHW0
names: Similarity
messages: Belongs to the EspG family.

1586287:BBK82 RS42340
gene id: 1586287:BBK82_RS42340
uniprot id: A0A1B2HV36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS39625
gene id: 1586287:BBK82_RS39625
uniprot id: A0A1B2HU21
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1586287:BBK82 RS22060
gene id: 1586287:BBK82_RS22060
uniprot id: A0A1B2HKU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1586287:BBK82 RS20175
gene id: 1586287:BBK82_RS20175
uniprot id: A0A1B2HJX6
names: Similarity
messages: Belongs to the tannase family.

1586287:BBK82 RS26925
gene id: 1586287:BBK82_RS26925
uniprot id: A0A1B2HN86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

1586287:BBK82 RS54200
gene id: 1586287:BBK82_RS54200
uniprot id: A0A1B2HJ78
names: Similarity
messages: Belongs to the peptidase C40 family.

1586287:BBK82 RS05670
gene id: 1586287:BBK82_RS05670
uniprot id: A0A1B2HD47
names: Similarity
messages: Belongs to the cytochrome P450 family.

1586287:BBK82 RS45020
gene id: 1586287:BBK82_RS45020
uniprot id: A0A1B2HWF6
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS30495
gene id: 1586287:BBK82_RS30495
uniprot id: A0A1B2HPW3
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1586287:BBK82 RS21655
gene id: 1586287:BBK82_RS21655
uniprot id: A0A1B2HYZ8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1586287:BBK82 RS21355
gene id: 1586287:BBK82_RS21355
uniprot id: A0A1B2HKI5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1586287:BBK82 RS18560
gene id: 1586287:BBK82_RS18560
uniprot id: A0A1B2HJ71
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

1586287:BBK82 RS12785
gene id: 1586287:BBK82_RS12785
uniprot id: A0A1B2HGH2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1586287:BBK82 RS10115
gene id: 1586287:BBK82_RS10115
uniprot id: A0A1B2HF55
names: Similarity
messages: Belongs to the PqqA family.

1586287:BBK82 RS45255
gene id: 1586287:BBK82_RS45255
uniprot id: A0A1B2HWF8
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1586287:BBK82 RS17595
gene id: 1586287:BBK82_RS17595
uniprot id: A0A1B2HIQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1586287:BBK82 RS28075
gene id: 1586287:BBK82_RS28075
uniprot id: A0A1B2HNR4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1586287:BBK82 RS39115
gene id: 1586287:BBK82_RS39115
uniprot id: A0A1B2HTT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1586287:BBK82 RS25675
gene id: 1586287:BBK82_RS25675
uniprot id: A0A1B2HMK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1586287:BBK82 RS21590
gene id: 1586287:BBK82_RS21590
uniprot id: A0A1B2HKM2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1586287:BBK82 RS43820
gene id: 1586287:BBK82_RS43820
uniprot id: A0A1B2HVS5
names: Similarity
messages: Belongs to the YciI family.

1586287:BBK82 RS01625
gene id: 1586287:BBK82_RS01625
uniprot id: A0A1B2HB65
names: Similarity
messages: Belongs to the histone deacetylase family.

1586287:BBK82 RS08890
gene id: 1586287:BBK82_RS08890
uniprot id: A0A1B2HY22
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1586287:BBK82 RS43010
gene id: 1586287:BBK82_RS43010
uniprot id: A0A1B2HVF6
names: Subcellular Location Annotation
messages: Cytoplasm

1586287:BBK82 RS40805
gene id: 1586287:BBK82_RS40805
uniprot id: A0A1B2HUF1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1586287:BBK82 RS37795
gene id: 1586287:BBK82_RS37795
uniprot id: A0A1B2HT33
names: Similarity
messages: Belongs to the DapA family.

1586287:BBK82 RS14595
gene id: 1586287:BBK82_RS14595
uniprot id: A0A1B2HHC8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS15965
gene id: 1586287:BBK82_RS15965
uniprot id: A0A1B2HHZ4
names: Similarity
messages: Belongs to the mycobacterial PPE family.

1586287:BBK82 RS05960
gene id: 1586287:BBK82_RS05960
uniprot id: A0A1B2HD94
names: Similarity
messages: Belongs to the peptidase S8 family.

1586287:BBK82 RS04325
gene id: 1586287:BBK82_RS04325
uniprot id: A0A1B2HCI4
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1586287:BBK82 RS45450
gene id: 1586287:BBK82_RS45450
uniprot id: A0A1B2HWL3
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1586287:BBK82 RS04380
gene id: 1586287:BBK82_RS04380
uniprot id: A0A1B2HCI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1586287:BBK82 RS24815
gene id: 1586287:BBK82_RS24815
uniprot id: A0A1B2HM76
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1586287:BBK82 RS20355
gene id: 1586287:BBK82_RS20355
uniprot id: A0A1B2HK34
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS15085
gene id: 1586287:BBK82_RS15085
uniprot id: A0A1B2HHL0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1586287:BBK82 RS11645
gene id: 1586287:BBK82_RS11645
uniprot id: A0A1B2HFZ9
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1586287:BBK82 RS14850
gene id: 1586287:BBK82_RS14850
uniprot id: A0A1B2HYG5
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

1586287:BBK82 RS23795
gene id: 1586287:BBK82_RS23795
uniprot id: A0A1B2HLN3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1586287:BBK82 RS15535
gene id: 1586287:BBK82_RS15535
uniprot id: A0A1B2HHR9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS15440
gene id: 1586287:BBK82_RS15440
uniprot id: A0A1B2HHP5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1586287:BBK82 RS25985
gene id: 1586287:BBK82_RS25985
uniprot id: A0A1B2HZ90
names: Similarity
messages: Belongs to the YciI family.

1586287:BBK82 RS17825
gene id: 1586287:BBK82_RS17825
uniprot id: A0A1B2HIT7
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1586287:BBK82 RS06255
gene id: 1586287:BBK82_RS06255
uniprot id: A0A1B2HDE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1586287:BBK82 RS23190
gene id: 1586287:BBK82_RS23190
uniprot id: A0A1B2HLE7
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1586287:BBK82 RS15970
gene id: 1586287:BBK82_RS15970
uniprot id: A0A1B2HHX3
names: Similarity
messages: Belongs to the EspG family.

1586287:BBK82 RS43745
gene id: 1586287:BBK82_RS43745
uniprot id: A0A1B2HVR8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1586287:BBK82 RS04765
gene id: 1586287:BBK82_RS04765
uniprot id: A0A1B2HCQ2
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1586287:BBK82 RS37260
gene id: 1586287:BBK82_RS37260
uniprot id: A0A1B2HST0
names: Similarity
messages: Belongs to the peptidase S1 family.

1586287:BBK82 RS14705
gene id: 1586287:BBK82_RS14705
uniprot id: A0A1B2HHD9
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1586287:BBK82 RS21185
gene id: 1586287:BBK82_RS21185
uniprot id: A0A1B2HKG6
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

1586287:BBK82 RS20475
gene id: 1586287:BBK82_RS20475
uniprot id: A0A1B2HK35
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS39525
gene id: 1586287:BBK82_RS39525
uniprot id: A0A1B2HTX5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

1586287:BBK82 RS36050
gene id: 1586287:BBK82_RS36050
uniprot id: A0A1B2HSF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1586287:BBK82 RS12995
gene id: 1586287:BBK82_RS12995
uniprot id: A0A1B2HGK8
names: Similarity
messages: Belongs to the Dps family.

1586287:BBK82 RS32875
gene id: 1586287:BBK82_RS32875
uniprot id: A0A1B2HQW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1586287:BBK82 RS17895
gene id: 1586287:BBK82_RS17895
uniprot id: A0A1B2HIV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

1586287:BBK82 RS25655
gene id: 1586287:BBK82_RS25655
uniprot id: A0A1B2HMM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1586287:BBK82 RS21440
gene id: 1586287:BBK82_RS21440
uniprot id: A0A1B2HKJ4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS30635
gene id: 1586287:BBK82_RS30635
uniprot id: A0A1B2HPW6
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

1586287:BBK82 RS24590
gene id: 1586287:BBK82_RS24590
uniprot id: A0A1B2HM22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1586287:BBK82 RS26165
gene id: 1586287:BBK82_RS26165
uniprot id: A0A1B2HMS4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1586287:BBK82 RS04795
gene id: 1586287:BBK82_RS04795
uniprot id: A0A1B2HCR6
names: Similarity
messages: Belongs to the peptidase M1 family.

1586287:BBK82 RS02345
gene id: 1586287:BBK82_RS02345
uniprot id: A0A1B2HBI1
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1586287:BBK82 RS45535
gene id: 1586287:BBK82_RS45535
uniprot id: A0A1B2HWL5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1586287:BBK82 RS00720
gene id: 1586287:BBK82_RS00720
uniprot id: A0A1B2HAR8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1586287:BBK82 RS02030
gene id: 1586287:BBK82_RS02030
uniprot id: A0A1B2HBE5
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1586287:BBK82 RS16180
gene id: 1586287:BBK82_RS16180
uniprot id: A0A1B2HI15
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.
messages: Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.
messages: Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.

1586287:BBK82 RS44815
gene id: 1586287:BBK82_RS44815
uniprot id: A0A1B2HWC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS03855
gene id: 1586287:BBK82_RS03855
uniprot id: A0A1B2HC98
names: Similarity
messages: Belongs to the Fur family.

1586287:BBK82 RS17775
gene id: 1586287:BBK82_RS17775
uniprot id: A0A1B2HIT1
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1586287:BBK82 RS12645
gene id: 1586287:BBK82_RS12645
uniprot id: A0A1B2HGE1
names: Similarity
messages: Belongs to the AHA1 family.

1586287:BBK82 RS18410
gene id: 1586287:BBK82_RS18410
uniprot id: A0A1B2HJ38
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1586287:BBK82 RS11800
gene id: 1586287:BBK82_RS11800
uniprot id: A0A1B2HFY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS01410
gene id: 1586287:BBK82_RS01410
uniprot id: A0A1B2HB33
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1586287:BBK82 RS38605
gene id: 1586287:BBK82_RS38605
uniprot id: A0A1B2HTG4
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1586287:BBK82 RS14435
gene id: 1586287:BBK82_RS14435
uniprot id: A0A1B2HH81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

1586287:BBK82 RS02180
gene id: 1586287:BBK82_RS02180
uniprot id: A0A1B2HBG2
names: Similarity
messages: Belongs to the arsA ATPase family.

1586287:BBK82 RS46820
gene id: 1586287:BBK82_RS46820
uniprot id: A0A1B2HX98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1586287:BBK82 RS16035
gene id: 1586287:BBK82_RS16035
uniprot id: A0A1B2HHY0
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS34075
gene id: 1586287:BBK82_RS34075
uniprot id: A0A1B2HZW4
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1586287:BBK82 RS03965
gene id: 1586287:BBK82_RS03965
uniprot id: A0A1B2HCC0
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1586287:BBK82 RS17145
gene id: 1586287:BBK82_RS17145
uniprot id: A0A1B2HIK1
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1586287:BBK82 RS32335
gene id: 1586287:BBK82_RS32335
uniprot id: A0A1B2HQP6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CoA-transferase III family. Frc subfamily.
messages: Homodimer.
messages: Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS12775
gene id: 1586287:BBK82_RS12775
uniprot id: A0A1B2HGH8
names: Similarity
messages: Belongs to the GSP E family.

1586287:BBK82 RS15630
gene id: 1586287:BBK82_RS15630
uniprot id: A0A1B2HHU5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS25670
gene id: 1586287:BBK82_RS25670
uniprot id: A0A1B2HMJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1586287:BBK82 RS11275
gene id: 1586287:BBK82_RS11275
uniprot id: A0A1B2HFN8
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS29210
gene id: 1586287:BBK82_RS29210
uniprot id: A0A1B2HPA0
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1586287:BBK82 RS18550
gene id: 1586287:BBK82_RS18550
uniprot id: A0A1B2HYS1
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS18470
gene id: 1586287:BBK82_RS18470
uniprot id: A0A1B2HJ56
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS17965
gene id: 1586287:BBK82_RS17965
uniprot id: A0A1B2HIW9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1586287:BBK82 RS09800
gene id: 1586287:BBK82_RS09800
uniprot id: A0A1B2HF29
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1586287:BBK82 RS04600
gene id: 1586287:BBK82_RS04600
uniprot id: A0A1B2HCQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1586287:BBK82 RS25340
gene id: 1586287:BBK82_RS25340
uniprot id: A0A1B2HME0
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1586287:BBK82 RS06820
gene id: 1586287:BBK82_RS06820
uniprot id: A0A1B2HDP3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS24775
gene id: 1586287:BBK82_RS24775
uniprot id: A0A1B2HM52
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS37105
gene id: 1586287:BBK82_RS37105
uniprot id: A0A1B2HSS2
names: Similarity
messages: Belongs to the thymidine kinase family.

1586287:BBK82 RS09345
gene id: 1586287:BBK82_RS09345
uniprot id: A0A1B2HET5
names: Similarity
messages: Belongs to the AHA1 family.

1586287:BBK82 RS23230
gene id: 1586287:BBK82_RS23230
uniprot id: A0A1B2HLE2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1586287:BBK82 RS43185
gene id: 1586287:BBK82_RS43185
uniprot id: A0A1B2HVH2
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

1586287:BBK82 RS13485
gene id: 1586287:BBK82_RS13485
uniprot id: A0A1B2HGT5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS43960
gene id: 1586287:BBK82_RS43960
uniprot id: A0A1B2HVW3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1586287:BBK82 RS29685
gene id: 1586287:BBK82_RS29685
uniprot id: A0A1B2HPF9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS27310
gene id: 1586287:BBK82_RS27310
uniprot id: A0A1B2HND8
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1586287:BBK82 RS06055
gene id: 1586287:BBK82_RS06055
uniprot id: A0A1B2HD99
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1586287:BBK82 RS44130
gene id: 1586287:BBK82_RS44130
uniprot id: A0A1B2HW36
names: Similarity
messages: Belongs to the tannase family.

1586287:BBK82 RS42930
gene id: 1586287:BBK82_RS42930
uniprot id: A0A1B2HVJ7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1586287:BBK82 RS01205
gene id: 1586287:BBK82_RS01205
uniprot id: A0A1B2HXH9
names: Similarity
messages: Belongs to the Vsr family.

1586287:BBK82 RS28555
gene id: 1586287:BBK82_RS28555
uniprot id: A0A1B2HNT8
names: Similarity
messages: Belongs to the citrate synthase family.

1586287:BBK82 RS07780
gene id: 1586287:BBK82_RS07780
uniprot id: A0A1B2HE61
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS29150
gene id: 1586287:BBK82_RS29150
uniprot id: A0A1B2HP92
names: Similarity
messages: Belongs to the DapA family.

1586287:BBK82 RS39000
gene id: 1586287:BBK82_RS39000
uniprot id: A0A1B2HTQ1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1586287:BBK82 RS14030
gene id: 1586287:BBK82_RS14030
uniprot id: A0A1B2HH22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1586287:BBK82 RS45615
gene id: 1586287:BBK82_RS45615
uniprot id: A0A1B2HWP9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS00845
gene id: 1586287:BBK82_RS00845
uniprot id: A0A1B2HAU4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1586287:BBK82 RS23295
gene id: 1586287:BBK82_RS23295
uniprot id: A0A1B2HLG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1586287:BBK82 RS21420
gene id: 1586287:BBK82_RS21420
uniprot id: A0A1B2HKK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

1586287:BBK82 RS35030
gene id: 1586287:BBK82_RS35030
uniprot id: A0A1B2HRV2
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1586287:BBK82 RS41010
gene id: 1586287:BBK82_RS41010
uniprot id: A0A1B2HUH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1586287:BBK82 RS12575
gene id: 1586287:BBK82_RS12575
uniprot id: A0A1B2HGC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1586287:BBK82 RS43280
gene id: 1586287:BBK82_RS43280
uniprot id: A0A1B2I0N6
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1586287:BBK82 RS31860
gene id: 1586287:BBK82_RS31860
uniprot id: A0A1B2HQF9
names: Similarity
messages: Belongs to the EspG family.

1586287:BBK82 RS25585
gene id: 1586287:BBK82_RS25585
uniprot id: A0A1B2HML0
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS02540
gene id: 1586287:BBK82_RS02540
uniprot id: A0A1B2HBM5
names: Similarity
messages: Belongs to the cytochrome P450 family.

1586287:BBK82 RS13360
gene id: 1586287:BBK82_RS13360
uniprot id: A0A1B2HYC1
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS13145
gene id: 1586287:BBK82_RS13145
uniprot id: A0A1B2HGP2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1586287:BBK82 RS02230
gene id: 1586287:BBK82_RS02230
uniprot id: A0A1B2HBH5
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1586287:BBK82 RS17695
gene id: 1586287:BBK82_RS17695
uniprot id: A0A1B2HIR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1586287:BBK82 RS43365
gene id: 1586287:BBK82_RS43365
uniprot id: A0A1B2I0L9
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS37190
gene id: 1586287:BBK82_RS37190
uniprot id: A0A1B2HSU4
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1586287:BBK82 RS29320
gene id: 1586287:BBK82_RS29320
uniprot id: A0A1B2HPA7
names: Similarity
messages: Belongs to the peptidase S33 family.

1586287:BBK82 RS10520
gene id: 1586287:BBK82_RS10520
uniprot id: A0A1B2HFD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS09535
gene id: 1586287:BBK82_RS09535
uniprot id: A0A1B2HEX8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1586287:BBK82 RS17685
gene id: 1586287:BBK82_RS17685
uniprot id: A0A1B2HIR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1586287:BBK82 RS08700
gene id: 1586287:BBK82_RS08700
uniprot id: A0A1B2HEJ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer.
messages: In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.
messages: In the N-terminal section; belongs to the LPG synthetase family.
messages: Membrane

1586287:BBK82 RS08615
gene id: 1586287:BBK82_RS08615
uniprot id: A0A1B2HEJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1586287:BBK82 RS19970
gene id: 1586287:BBK82_RS19970
uniprot id: A0A1B2HJU8
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS38485
gene id: 1586287:BBK82_RS38485
uniprot id: A0A1B2HTD5
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS24865
gene id: 1586287:BBK82_RS24865
uniprot id: A0A1B2HZ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS45365
gene id: 1586287:BBK82_RS45365
uniprot id: A0A1B2HWI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1586287:BBK82 RS17540
gene id: 1586287:BBK82_RS17540
uniprot id: A0A1B2HIR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1586287:BBK82 RS42200
gene id: 1586287:BBK82_RS42200
uniprot id: A0A1B2HV16
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1586287:BBK82 RS32375
gene id: 1586287:BBK82_RS32375
uniprot id: A0A1B2HQP0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1586287:BBK82 RS04490
gene id: 1586287:BBK82_RS04490
uniprot id: A0A1B2HCN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS10860
gene id: 1586287:BBK82_RS10860
uniprot id: A0A1B2HFK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1586287:BBK82 RS38625
gene id: 1586287:BBK82_RS38625
uniprot id: A0A1B2HTK2
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS22680
gene id: 1586287:BBK82_RS22680
uniprot id: A0A1B2HL67
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS21930
gene id: 1586287:BBK82_RS21930
uniprot id: A0A1B2HKS8
names: Similarity
messages: Belongs to the allantoicase family.

1586287:BBK82 RS19350
gene id: 1586287:BBK82_RS19350
uniprot id: A0A1B2HJJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1586287:BBK82 RS10835
gene id: 1586287:BBK82_RS10835
uniprot id: A0A1B2HY63
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1586287:BBK82 RS11320
gene id: 1586287:BBK82_RS11320
uniprot id: A0A1B2HFT1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1586287:BBK82 RS15205
gene id: 1586287:BBK82_RS15205
uniprot id: A0A1B2HHK9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1586287:BBK82 RS36290
gene id: 1586287:BBK82_RS36290
uniprot id: A0A1B2HSG3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1586287:BBK82 RS14180
gene id: 1586287:BBK82_RS14180
uniprot id: A0A1B2HH52
names: Similarity
messages: Belongs to the peptidase S66 family.

1586287:BBK82 RS00325
gene id: 1586287:BBK82_RS00325
uniprot id: A0A1B2HAL0
names: Similarity
messages: Belongs to the cytochrome P450 family.

1586287:BBK82 RS02405
gene id: 1586287:BBK82_RS02405
uniprot id: A0A1B2HBI4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1586287:BBK82 RS46035
gene id: 1586287:BBK82_RS46035
uniprot id: A0A1B2HWX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1586287:BBK82 RS17780
gene id: 1586287:BBK82_RS17780
uniprot id: A0A1B2HIT3
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1586287:BBK82 RS23005
gene id: 1586287:BBK82_RS23005
uniprot id: A0A1B2HLA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1586287:BBK82 RS39030
gene id: 1586287:BBK82_RS39030
uniprot id: A0A1B2HTN6
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

1586287:BBK82 RS22380
gene id: 1586287:BBK82_RS22380
uniprot id: A0A1B2HL17
names: Similarity
messages: Belongs to the threonine aldolase family.

1586287:BBK82 RS28720
gene id: 1586287:BBK82_RS28720
uniprot id: A0A1B2HP25
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1586287:BBK82 RS13470
gene id: 1586287:BBK82_RS13470
uniprot id: A0A1B2HGU1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1586287:BBK82 RS23345
gene id: 1586287:BBK82_RS23345
uniprot id: A0A1B2HLG9
names: Similarity
messages: Belongs to the TrpC family.

1586287:BBK82 RS40630
gene id: 1586287:BBK82_RS40630
uniprot id: A0A1B2HUH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS35195
gene id: 1586287:BBK82_RS35195
uniprot id: A0A1B2HRY0
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS26425
gene id: 1586287:BBK82_RS26425
uniprot id: A0A1B2HN11
names: Similarity
messages: Belongs to the asp23 family.

1586287:BBK82 RS04570
gene id: 1586287:BBK82_RS04570
uniprot id: A0A1B2HCL1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1586287:BBK82 RS00070
gene id: 1586287:BBK82_RS00070
uniprot id: A0A1B2HAH3
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

1586287:BBK82 RS43335
gene id: 1586287:BBK82_RS43335
uniprot id: A0A1B2HVJ3
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS16700
gene id: 1586287:BBK82_RS16700
uniprot id: A0A1B2HIA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

1586287:BBK82 RS42230
gene id: 1586287:BBK82_RS42230
uniprot id: A0A1B2HV79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS33390
gene id: 1586287:BBK82_RS33390
uniprot id: A0A1B2HR42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS34590
gene id: 1586287:BBK82_RS34590
uniprot id: A0A1B2HZW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS13535
gene id: 1586287:BBK82_RS13535
uniprot id: A0A1B2HGV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS46040
gene id: 1586287:BBK82_RS46040
uniprot id: A0A1B2HWX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1586287:BBK82 RS46365
gene id: 1586287:BBK82_RS46365
uniprot id: A0A1B2I0V8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

1586287:BBK82 RS32325
gene id: 1586287:BBK82_RS32325
uniprot id: A0A1B2HQQ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1586287:BBK82 RS43505
gene id: 1586287:BBK82_RS43505
uniprot id: A0A1B2HVN4
names: Similarity
messages: Belongs to the CsoR family.

1586287:BBK82 RS14485
gene id: 1586287:BBK82_RS14485
uniprot id: A0A1B2HHB2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1586287:BBK82 RS17655
gene id: 1586287:BBK82_RS17655
uniprot id: A0A1B2HIR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1586287:BBK82 RS04485
gene id: 1586287:BBK82_RS04485
uniprot id: A0A1B2HCK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS18575
gene id: 1586287:BBK82_RS18575
uniprot id: A0A1B2HJ65
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS43305
gene id: 1586287:BBK82_RS43305
uniprot id: A0A1B2HVM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1586287:BBK82 RS33710
gene id: 1586287:BBK82_RS33710
uniprot id: A0A1B2HRD3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1586287:BBK82 RS23150
gene id: 1586287:BBK82_RS23150
uniprot id: A0A1B2HLE0
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

1586287:BBK82 RS09830
gene id: 1586287:BBK82_RS09830
uniprot id: A0A1B2HF38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1586287:BBK82 RS15910
gene id: 1586287:BBK82_RS15910
uniprot id: A0A1B2HHY5
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1586287:BBK82 RS20435
gene id: 1586287:BBK82_RS20435
uniprot id: A0A1B2HK36
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1586287:BBK82 RS06515
gene id: 1586287:BBK82_RS06515
uniprot id: A0A1B2HDH9
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS44630
gene id: 1586287:BBK82_RS44630
uniprot id: A0A1B2HW91
names: Similarity
messages: Belongs to the beta-eliminating lyase family.

1586287:BBK82 RS30930
gene id: 1586287:BBK82_RS30930
uniprot id: A0A1B2HQ31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS20725
gene id: 1586287:BBK82_RS20725
uniprot id: A0A1B2HYW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1586287:BBK82 RS35970
gene id: 1586287:BBK82_RS35970
uniprot id: A0A1B2HSC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1586287:BBK82 RS19485
gene id: 1586287:BBK82_RS19485
uniprot id: A0A1B2HJK8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1586287:BBK82 RS23515
gene id: 1586287:BBK82_RS23515
uniprot id: A0A1B2HLK4
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1586287:BBK82 RS19690
gene id: 1586287:BBK82_RS19690
uniprot id: A0A1B2HJQ4
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS17220
gene id: 1586287:BBK82_RS17220
uniprot id: A0A1B2HII1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1586287:BBK82 RS39360
gene id: 1586287:BBK82_RS39360
uniprot id: A0A1B2HTU0
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1586287:BBK82 RS44105
gene id: 1586287:BBK82_RS44105
uniprot id: A0A1B2HW11
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS37655
gene id: 1586287:BBK82_RS37655
uniprot id: A0A1B2HT16
names: Similarity
messages: Belongs to the EspG family.

1586287:BBK82 RS05400
gene id: 1586287:BBK82_RS05400
uniprot id: A0A1B2HXN9
names: Cofactor
messages: Binds 1 FAD per subunit.

1586287:BBK82 RS11715
gene id: 1586287:BBK82_RS11715
uniprot id: A0A1B2HY86
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1586287:BBK82 RS03875
gene id: 1586287:BBK82_RS03875
uniprot id: A0A1B2HCB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS17355
gene id: 1586287:BBK82_RS17355
uniprot id: A0A1B2HIK6
names: Similarity
messages: Belongs to the UPF0336 family.

1586287:BBK82 RS28575
gene id: 1586287:BBK82_RS28575
uniprot id: A0A1B2HNZ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1586287:BBK82 RS45735
gene id: 1586287:BBK82_RS45735
uniprot id: A0A1B2HWQ1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1586287:BBK82 RS23240
gene id: 1586287:BBK82_RS23240
uniprot id: A0A1B2HLF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1586287:BBK82 RS07145
gene id: 1586287:BBK82_RS07145
uniprot id: A0A1B2HDV8
names: Similarity
messages: Belongs to the PhoU family.

1586287:BBK82 RS35410
gene id: 1586287:BBK82_RS35410
uniprot id: A0A1B2HRY2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1586287:BBK82 RS45035
gene id: 1586287:BBK82_RS45035
uniprot id: A0A1B2HWC6
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1586287:BBK82 RS10265
gene id: 1586287:BBK82_RS10265
uniprot id: A0A1B2HF57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS30425
gene id: 1586287:BBK82_RS30425
uniprot id: A0A1B2HZK8
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1586287:BBK82 RS01300
gene id: 1586287:BBK82_RS01300
uniprot id: A0A1B2HXD3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1586287:BBK82 RS20590
gene id: 1586287:BBK82_RS20590
uniprot id: A0A1B2HK60
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1586287:BBK82 RS47135
gene id: 1586287:BBK82_RS47135
uniprot id: A0A1B2I106
names: Similarity
messages: Belongs to the cytochrome P450 family.

1586287:BBK82 RS29570
gene id: 1586287:BBK82_RS29570
uniprot id: A0A1B2HPE0
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1586287:BBK82 RS41780
gene id: 1586287:BBK82_RS41780
uniprot id: A0A1B2HV03
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1586287:BBK82 RS08715
gene id: 1586287:BBK82_RS08715
uniprot id: A0A1B2HEJ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1586287:BBK82 RS06075
gene id: 1586287:BBK82_RS06075
uniprot id: A0A1B2HDC2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1586287:BBK82 RS31930
gene id: 1586287:BBK82_RS31930
uniprot id: A0A1B2HQI2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1586287:BBK82 RS22030
gene id: 1586287:BBK82_RS22030
uniprot id: A0A1B2HKU7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1586287:BBK82 RS37575
gene id: 1586287:BBK82_RS37575
uniprot id: A0A1B2HT11
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1586287:BBK82 RS14825
gene id: 1586287:BBK82_RS14825
uniprot id: A0A1B2HHG6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1586287:BBK82 RS17705
gene id: 1586287:BBK82_RS17705
uniprot id: A0A1B2HIR7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1586287:BBK82 RS33425
gene id: 1586287:BBK82_RS33425
uniprot id: A0A1B2HR66
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1586287:BBK82 RS17940
gene id: 1586287:BBK82_RS17940
uniprot id: A0A1B2HIV8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS13510
gene id: 1586287:BBK82_RS13510
uniprot id: A0A1B2HGT6
names: Similarity
messages: Belongs to the EspG family.

1586287:BBK82 RS36445
gene id: 1586287:BBK82_RS36445
uniprot id: A0A1B2HSH8
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

1586287:BBK82 RS39665
gene id: 1586287:BBK82_RS39665
uniprot id: A0A1B2I0C8
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

1586287:BBK82 RS10415
gene id: 1586287:BBK82_RS10415
uniprot id: A0A1B2HFB0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS26225
gene id: 1586287:BBK82_RS26225
uniprot id: A0A1B2HMV3
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1586287:BBK82 RS45360
gene id: 1586287:BBK82_RS45360
uniprot id: A0A1B2HWN4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1586287:BBK82 RS31140
gene id: 1586287:BBK82_RS31140
uniprot id: A0A1B2HQ72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1586287:BBK82 RS40200
gene id: 1586287:BBK82_RS40200
uniprot id: A0A1B2HU85
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1586287:BBK82 RS31620
gene id: 1586287:BBK82_RS31620
uniprot id: A0A1B2HQD4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1586287:BBK82 RS32500
gene id: 1586287:BBK82_RS32500
uniprot id: A0A1B2HQQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS19320
gene id: 1586287:BBK82_RS19320
uniprot id: A0A1B2HJJ3
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1586287:BBK82 RS11725
gene id: 1586287:BBK82_RS11725
uniprot id: A0A1B2HG01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS43455
gene id: 1586287:BBK82_RS43455
uniprot id: A0A1B2HVP9
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1586287:BBK82 RS14155
gene id: 1586287:BBK82_RS14155
uniprot id: A0A1B2HH40
names: Similarity
messages: Belongs to the FPG family.

1586287:BBK82 RS22070
gene id: 1586287:BBK82_RS22070
uniprot id: A0A1B2HKV6
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1586287:BBK82 RS07945
gene id: 1586287:BBK82_RS07945
uniprot id: A0A1B2HE59
names: Similarity
messages: Belongs to the thymidylate kinase family.

1586287:BBK82 RS43050
gene id: 1586287:BBK82_RS43050
uniprot id: A0A1B2HVL3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS02095
gene id: 1586287:BBK82_RS02095
uniprot id: A0A1B2HBG0
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1586287:BBK82 RS35435
gene id: 1586287:BBK82_RS35435
uniprot id: A0A1B2HS54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

1586287:BBK82 RS17645
gene id: 1586287:BBK82_RS17645
uniprot id: A0A1B2HIQ9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1586287:BBK82 RS46270
gene id: 1586287:BBK82_RS46270
uniprot id: A0A1B2I0U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS17715
gene id: 1586287:BBK82_RS17715
uniprot id: A0A1B2HIS1
names: Similarity
messages: Belongs to the peptidase S8 family.

1586287:BBK82 RS02565
gene id: 1586287:BBK82_RS02565
uniprot id: A0A1B2HBL3
names: Similarity
messages: Belongs to the peptidase S33 family.

1586287:BBK82 RS23610
gene id: 1586287:BBK82_RS23610
uniprot id: A0A1B2HLM6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1586287:BBK82 RS33935
gene id: 1586287:BBK82_RS33935
uniprot id: A0A1B2HRC5
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1586287:BBK82 RS35620
gene id: 1586287:BBK82_RS35620
uniprot id: A0A1B2HS40
names: Similarity
messages: Belongs to the peptidase S33 family.

1586287:BBK82 RS04395
gene id: 1586287:BBK82_RS04395
uniprot id: A0A1B2HXQ8
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

1586287:BBK82 RS14715
gene id: 1586287:BBK82_RS14715
uniprot id: A0A1B2HHE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1586287:BBK82 RS31790
gene id: 1586287:BBK82_RS31790
uniprot id: A0A1B2HQD6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

1586287:BBK82 RS06100
gene id: 1586287:BBK82_RS06100
uniprot id: A0A1B2HXT7
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1586287:BBK82 RS23135
gene id: 1586287:BBK82_RS23135
uniprot id: A0A1B2HLD0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS21940
gene id: 1586287:BBK82_RS21940
uniprot id: A0A1B2HYZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS27375
gene id: 1586287:BBK82_RS27375
uniprot id: A0A1B2HZE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1586287:BBK82 RS24615
gene id: 1586287:BBK82_RS24615
uniprot id: A0A1B2HM20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1586287:BBK82 RS12070
gene id: 1586287:BBK82_RS12070
uniprot id: A0A1B2HG61
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1586287:BBK82 RS46400
gene id: 1586287:BBK82_RS46400
uniprot id: A0A1B2I0Y0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1586287:BBK82 RS00555
gene id: 1586287:BBK82_RS00555
uniprot id: A0A1B2HAQ6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS26395
gene id: 1586287:BBK82_RS26395
uniprot id: A0A1B2HMZ8
names: Similarity
messages: Belongs to the IucA/IucC family.

1586287:BBK82 RS07775
gene id: 1586287:BBK82_RS07775
uniprot id: A0A1B2HXY2
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS38460
gene id: 1586287:BBK82_RS38460
uniprot id: A0A1B2HTD8
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS21750
gene id: 1586287:BBK82_RS21750
uniprot id: A0A1B2HKP6
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS21110
gene id: 1586287:BBK82_RS21110
uniprot id: A0A1B2HKD7
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

1586287:BBK82 RS12300
gene id: 1586287:BBK82_RS12300
uniprot id: A0A1B2HGA0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1586287:BBK82 RS04770
gene id: 1586287:BBK82_RS04770
uniprot id: A0A1B2HCN3
names: Similarity
messages: Belongs to the FPG family.

1586287:BBK82 RS45125
gene id: 1586287:BBK82_RS45125
uniprot id: A0A1B2HWH7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1586287:BBK82 RS23765
gene id: 1586287:BBK82_RS23765
uniprot id: A0A1B2HLN1
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1586287:BBK82 RS28350
gene id: 1586287:BBK82_RS28350
uniprot id: A0A1B2HNV9
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS45900
gene id: 1586287:BBK82_RS45900
uniprot id: A0A1B2HWS2
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1586287:BBK82 RS32270
gene id: 1586287:BBK82_RS32270
uniprot id: A0A1B2HZP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS26055
gene id: 1586287:BBK82_RS26055
uniprot id: A0A1B2HMS7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1586287:BBK82 RS02335
gene id: 1586287:BBK82_RS02335
uniprot id: A0A1B2HBJ6
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1586287:BBK82 RS34360
gene id: 1586287:BBK82_RS34360
uniprot id: A0A1B2HRJ8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS24650
gene id: 1586287:BBK82_RS24650
uniprot id: A0A1B2HZ63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1586287:BBK82 RS35770
gene id: 1586287:BBK82_RS35770
uniprot id: A0A1B2HS97
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS21360
gene id: 1586287:BBK82_RS21360
uniprot id: A0A1B2HKI3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1586287:BBK82 RS13920
gene id: 1586287:BBK82_RS13920
uniprot id: A0A1B2HH11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1586287:BBK82 RS38630
gene id: 1586287:BBK82_RS38630
uniprot id: A0A1B2HTI9
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1586287:BBK82 RS12490
gene id: 1586287:BBK82_RS12490
uniprot id: A0A1B2HGC3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS33790
gene id: 1586287:BBK82_RS33790
uniprot id: A0A1B2HR99
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS36990
gene id: 1586287:BBK82_RS36990
uniprot id: A0A1B2HST1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1586287:BBK82 RS06010
gene id: 1586287:BBK82_RS06010
uniprot id: A0A1B2HD98
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1586287:BBK82 RS07215
gene id: 1586287:BBK82_RS07215
uniprot id: A0A1B2HDU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS07195
gene id: 1586287:BBK82_RS07195
uniprot id: A0A1B2HDY3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1586287:BBK82 RS40540
gene id: 1586287:BBK82_RS40540
uniprot id: A0A1B2HUD9
names: Similarity
messages: Belongs to the AHA1 family.

1586287:BBK82 RS16860
gene id: 1586287:BBK82_RS16860
uniprot id: A0A1B2HIC2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1586287:BBK82 RS33705
gene id: 1586287:BBK82_RS33705
uniprot id: A0A1B2HR94
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS44410
gene id: 1586287:BBK82_RS44410
uniprot id: A0A1B2HW26
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1586287:BBK82 RS22965
gene id: 1586287:BBK82_RS22965
uniprot id: A0A1B2HL93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1586287:BBK82 RS32965
gene id: 1586287:BBK82_RS32965
uniprot id: A0A1B2HZR1
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1586287:BBK82 RS23040
gene id: 1586287:BBK82_RS23040
uniprot id: A0A1B2HZ23
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1586287:BBK82 RS36510
gene id: 1586287:BBK82_RS36510
uniprot id: A0A1B2HSL6
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1586287:BBK82 RS02630
gene id: 1586287:BBK82_RS02630
uniprot id: A0A1B2HBP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1586287:BBK82 RS17750
gene id: 1586287:BBK82_RS17750
uniprot id: A0A1B2HIS6
names: Similarity
messages: Belongs to the EccD/Snm4 family.

1586287:BBK82 RS09500
gene id: 1586287:BBK82_RS09500
uniprot id: A0A1B2HEW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1586287:BBK82 RS22545
gene id: 1586287:BBK82_RS22545
uniprot id: A0A1B2HL45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1586287:BBK82 RS23755
gene id: 1586287:BBK82_RS23755
uniprot id: A0A1B2HLN7
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS33915
gene id: 1586287:BBK82_RS33915
uniprot id: A0A1B2HRC0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS20145
gene id: 1586287:BBK82_RS20145
uniprot id: A0A1B2HJX4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1586287:BBK82 RS45000
gene id: 1586287:BBK82_RS45000
uniprot id: A0A1B2HWD1
names: Similarity
messages: Belongs to the peptidase C40 family.

1586287:BBK82 RS37585
gene id: 1586287:BBK82_RS37585
uniprot id: A0A1B2HT19
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

1586287:BBK82 RS00730
gene id: 1586287:BBK82_RS00730
uniprot id: A0A1B2HAR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1586287:BBK82 RS37750
gene id: 1586287:BBK82_RS37750
uniprot id: A0A1B2HT25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

1586287:BBK82 RS30715
gene id: 1586287:BBK82_RS30715
uniprot id: A0A1B2HPX7
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1586287:BBK82 RS09460
gene id: 1586287:BBK82_RS09460
uniprot id: A0A1B2HEW4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1586287:BBK82 RS23715
gene id: 1586287:BBK82_RS23715
uniprot id: A0A1B2HLM4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS33355
gene id: 1586287:BBK82_RS33355
uniprot id: A0A1B2HR38
names: Similarity
messages: Belongs to the peptidase S1 family.

1586287:BBK82 RS03425
gene id: 1586287:BBK82_RS03425
uniprot id: A0A1B2HC53
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1586287:BBK82 RS22540
gene id: 1586287:BBK82_RS22540
uniprot id: A0A1B2HL42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1586287:BBK82 RS24630
gene id: 1586287:BBK82_RS24630
uniprot id: A0A1B2HM16
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1586287:BBK82 RS12550
gene id: 1586287:BBK82_RS12550
uniprot id: A0A1B2HGD9
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1586287:BBK82 RS23485
gene id: 1586287:BBK82_RS23485
uniprot id: A0A1B2HLI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1586287:BBK82 RS39225
gene id: 1586287:BBK82_RS39225
uniprot id: A0A1B2HTW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS30255
gene id: 1586287:BBK82_RS30255
uniprot id: A0A1B2HPT4
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1586287:BBK82 RS02575
gene id: 1586287:BBK82_RS02575
uniprot id: A0A1B2HBN7
names: Similarity
messages: Belongs to the cytochrome P450 family.

1586287:BBK82 RS01920
gene id: 1586287:BBK82_RS01920
uniprot id: A0A1B2HBB6
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1586287:BBK82 RS24685
gene id: 1586287:BBK82_RS24685
uniprot id: A0A1B2HM28
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS10985
gene id: 1586287:BBK82_RS10985
uniprot id: A0A1B2HFP3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1586287:BBK82 RS20675
gene id: 1586287:BBK82_RS20675
uniprot id: A0A1B2HK56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1586287:BBK82 RS27280
gene id: 1586287:BBK82_RS27280
uniprot id: A0A1B2HNF3
names: Function
messages: Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

1586287:BBK82 RS38800
gene id: 1586287:BBK82_RS38800
uniprot id: A0A1B2HTJ3
names: Similarity
messages: Belongs to the fructosamine kinase family.

1586287:BBK82 RS22920
gene id: 1586287:BBK82_RS22920
uniprot id: A0A1B2HL96
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1586287:BBK82 RS05760
gene id: 1586287:BBK82_RS05760
uniprot id: A0A1B2HD43
names: Similarity
messages: Belongs to the CdaR family.

1586287:BBK82 RS17700
gene id: 1586287:BBK82_RS17700
uniprot id: A0A1B2HIU9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1586287:BBK82 RS38385
gene id: 1586287:BBK82_RS38385
uniprot id: A0A1B2HTC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS22925
gene id: 1586287:BBK82_RS22925
uniprot id: A0A1B2HLB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1586287:BBK82 RS19770
gene id: 1586287:BBK82_RS19770
uniprot id: A0A1B2HJT9
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS31990
gene id: 1586287:BBK82_RS31990
uniprot id: A0A1B2HQL8
names: Similarity
messages: Belongs to the pirin family.

1586287:BBK82 RS32580
gene id: 1586287:BBK82_RS32580
uniprot id: A0A1B2HQR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1586287:BBK82 RS42765
gene id: 1586287:BBK82_RS42765
uniprot id: A0A1B2HVA6
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS45865
gene id: 1586287:BBK82_RS45865
uniprot id: A0A1B2HWR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1586287:BBK82 RS38995
gene id: 1586287:BBK82_RS38995
uniprot id: A0A1B2HTM4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1586287:BBK82 RS36245
gene id: 1586287:BBK82_RS36245
uniprot id: A0A1B2HSE6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS11815
gene id: 1586287:BBK82_RS11815
uniprot id: A0A1B2HG28
names: Similarity
messages: Belongs to the CutC family.

1586287:BBK82 RS29420
gene id: 1586287:BBK82_RS29420
uniprot id: A0A1B2HPA1
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS17945
gene id: 1586287:BBK82_RS17945
uniprot id: A0A1B2HIV5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS43795
gene id: 1586287:BBK82_RS43795
uniprot id: A0A1B2I0K7
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1586287:BBK82 RS26100
gene id: 1586287:BBK82_RS26100
uniprot id: A0A1B2HMU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS28405
gene id: 1586287:BBK82_RS28405
uniprot id: A0A1B2HNU0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1586287:BBK82 RS18545
gene id: 1586287:BBK82_RS18545
uniprot id: A0A1B2HJ69
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS00765
gene id: 1586287:BBK82_RS00765
uniprot id: A0A1B2HAU3
names: Similarity
messages: Belongs to the GcvT family.

1586287:BBK82 RS16225
gene id: 1586287:BBK82_RS16225
uniprot id: A0A1B2HI49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1586287:BBK82 RS04150
gene id: 1586287:BBK82_RS04150
uniprot id: A0A1B2HCD9
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS36010
gene id: 1586287:BBK82_RS36010
uniprot id: A0A1B2HS93
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

1586287:BBK82 RS15375
gene id: 1586287:BBK82_RS15375
uniprot id: A0A1B2HHQ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS37290
gene id: 1586287:BBK82_RS37290
uniprot id: A0A1B2HSZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS17285
gene id: 1586287:BBK82_RS17285
uniprot id: A0A1B2HIJ4
names: Similarity
messages: Belongs to the UPF0234 family.

1586287:BBK82 RS37705
gene id: 1586287:BBK82_RS37705
uniprot id: A0A1B2HT39
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS09910
gene id: 1586287:BBK82_RS09910
uniprot id: A0A1B2HF59
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS17375
gene id: 1586287:BBK82_RS17375
uniprot id: A0A1B2HIM1
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1586287:BBK82 RS23320
gene id: 1586287:BBK82_RS23320
uniprot id: A0A1B2HLF1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1586287:BBK82 RS33215
gene id: 1586287:BBK82_RS33215
uniprot id: A0A1B2HR33
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1586287:BBK82 RS27155
gene id: 1586287:BBK82_RS27155
uniprot id: A0A1B2HZC3
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1586287:BBK82 RS15905
gene id: 1586287:BBK82_RS15905
uniprot id: A0A1B2HHY2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1586287:BBK82 RS29995
gene id: 1586287:BBK82_RS29995
uniprot id: A0A1B2HZK2
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS10230
gene id: 1586287:BBK82_RS10230
uniprot id: A0A1B2HY62
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

1586287:BBK82 RS31760
gene id: 1586287:BBK82_RS31760
uniprot id: A0A1B2HQH0
names: Similarity
messages: Belongs to the asparagine synthetase family.

1586287:BBK82 RS09290
gene id: 1586287:BBK82_RS09290
uniprot id: A0A1B2HY32
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1586287:BBK82 RS28090
gene id: 1586287:BBK82_RS28090
uniprot id: A0A1B2HNP4
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1586287:BBK82 RS23680
gene id: 1586287:BBK82_RS23680
uniprot id: A0A1B2HLL2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS18285
gene id: 1586287:BBK82_RS18285
uniprot id: A0A1B2HJ16
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1586287:BBK82 RS19725
gene id: 1586287:BBK82_RS19725
uniprot id: A0A1B2HJQ5
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

1586287:BBK82 RS22500
gene id: 1586287:BBK82_RS22500
uniprot id: A0A1B2HL26
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1586287:BBK82 RS15620
gene id: 1586287:BBK82_RS15620
uniprot id: A0A1B2HHT3
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1586287:BBK82 RS14545
gene id: 1586287:BBK82_RS14545
uniprot id: A0A1B2HH97
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1586287:BBK82 RS01160
gene id: 1586287:BBK82_RS01160
uniprot id: A0A1B2HAZ0
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1586287:BBK82 RS01890
gene id: 1586287:BBK82_RS01890
uniprot id: A0A1B2HBC3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1586287:BBK82 RS16255
gene id: 1586287:BBK82_RS16255
uniprot id: A0A1B2HI46
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1586287:BBK82 RS08005
gene id: 1586287:BBK82_RS08005
uniprot id: A0A1B2HE62
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1586287:BBK82 RS03895
gene id: 1586287:BBK82_RS03895
uniprot id: A0A1B2HCF2
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1586287:BBK82 RS24690
gene id: 1586287:BBK82_RS24690
uniprot id: A0A1B2HM33
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1586287:BBK82 RS05605
gene id: 1586287:BBK82_RS05605
uniprot id: A0A1B2HD37
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS11290
gene id: 1586287:BBK82_RS11290
uniprot id: A0A1B2HFT5
names: Similarity
messages: Belongs to the asparagine synthetase family.

1586287:BBK82 RS40475
gene id: 1586287:BBK82_RS40475
uniprot id: A0A1B2HUC9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1586287:BBK82 RS16865
gene id: 1586287:BBK82_RS16865
uniprot id: A0A1B2HIE9
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1586287:BBK82 RS36980
gene id: 1586287:BBK82_RS36980
uniprot id: A0A1B2HSP0
names: Similarity
messages: Belongs to the peptidase S66 family.

1586287:BBK82 RS06200
gene id: 1586287:BBK82_RS06200
uniprot id: A0A1B2HDC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1586287:BBK82 RS17925
gene id: 1586287:BBK82_RS17925
uniprot id: A0A1B2HIW0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1586287:BBK82 RS16740
gene id: 1586287:BBK82_RS16740
uniprot id: A0A1B2HI89
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1586287:BBK82 RS04525
gene id: 1586287:BBK82_RS04525
uniprot id: A0A1B2HCL4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1586287:BBK82 RS06145
gene id: 1586287:BBK82_RS06145
uniprot id: A0A1B2HDB8
names: Similarity
messages: Belongs to the peptidase S58 family.

1586287:BBK82 RS21965
gene id: 1586287:BBK82_RS21965
uniprot id: A0A1B2HKT2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1586287:BBK82 RS30925
gene id: 1586287:BBK82_RS30925
uniprot id: A0A1B2HQ03
names: Similarity
messages: Belongs to the neocarzinostatin family.

1586287:BBK82 RS38870
gene id: 1586287:BBK82_RS38870
uniprot id: A0A1B2HTN2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1586287:BBK82 RS22615
gene id: 1586287:BBK82_RS22615
uniprot id: A0A1B2HYY9
names: Similarity
messages: Belongs to the peptidase M16 family.

1586287:BBK82 RS05385
gene id: 1586287:BBK82_RS05385
uniprot id: A0A1B2HD36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1586287:BBK82 RS14635
gene id: 1586287:BBK82_RS14635
uniprot id: A0A1B2HHA3
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1586287:BBK82 RS43850
gene id: 1586287:BBK82_RS43850
uniprot id: A0A1B2I0L2
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

1586287:BBK82 RS23645
gene id: 1586287:BBK82_RS23645
uniprot id: A0A1B2HLK9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS00060
gene id: 1586287:BBK82_RS00060
uniprot id: A0A1B2HAH0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

1586287:BBK82 RS01650
gene id: 1586287:BBK82_RS01650
uniprot id: A0A1B2HB85
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1586287:BBK82 RS34645
gene id: 1586287:BBK82_RS34645
uniprot id: A0A1B2HRP4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS19735
gene id: 1586287:BBK82_RS19735
uniprot id: A0A1B2HJQ6
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1586287:BBK82 RS46610
gene id: 1586287:BBK82_RS46610
uniprot id: A0A1B2HX50
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

1586287:BBK82 RS01960
gene id: 1586287:BBK82_RS01960
uniprot id: A0A1B2HBC1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS27545
gene id: 1586287:BBK82_RS27545
uniprot id: A0A1B2HNH8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1586287:BBK82 RS35875
gene id: 1586287:BBK82_RS35875
uniprot id: A0A1B2I009
names: Similarity
messages: Belongs to the thioesterase family.

1586287:BBK82 RS21595
gene id: 1586287:BBK82_RS21595
uniprot id: A0A1B2HKP7
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

1586287:BBK82 RS35715
gene id: 1586287:BBK82_RS35715
uniprot id: A0A1B2HS82
names: Similarity
messages: Belongs to the clavaminate synthase family.

1586287:BBK82 RS29790
gene id: 1586287:BBK82_RS29790
uniprot id: A0A1B2HPK1
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1586287:BBK82 RS18200
gene id: 1586287:BBK82_RS18200
uniprot id: A0A1B2HJ12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

1586287:BBK82 RS17545
gene id: 1586287:BBK82_RS17545
uniprot id: A0A1B2HIP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1586287:BBK82 RS45780
gene id: 1586287:BBK82_RS45780
uniprot id: A0A1B2I0S5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS05260
gene id: 1586287:BBK82_RS05260
uniprot id: A0A1B2HCW5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1586287:BBK82 RS02360
gene id: 1586287:BBK82_RS02360
uniprot id: A0A1B2HBJ5
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1586287:BBK82 RS31445
gene id: 1586287:BBK82_RS31445
uniprot id: A0A1B2HQ94
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS21910
gene id: 1586287:BBK82_RS21910
uniprot id: A0A1B2HKS7
names: Similarity
messages: Belongs to the HIBADH-related family.

1586287:BBK82 RS52085
gene id: 1586287:BBK82_RS52085
uniprot id: A0A1B2HU47
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1586287:BBK82 RS09795
gene id: 1586287:BBK82_RS09795
uniprot id: A0A1B2HF13
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1586287:BBK82 RS38715
gene id: 1586287:BBK82_RS38715
uniprot id: A0A1B2HTI1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1586287:BBK82 RS28010
gene id: 1586287:BBK82_RS28010
uniprot id: A0A1B2HNQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

1586287:BBK82 RS13200
gene id: 1586287:BBK82_RS13200
uniprot id: A0A1B2HGQ3
names: Similarity
messages: Belongs to the FGGY kinase family.

1586287:BBK82 RS02300
gene id: 1586287:BBK82_RS02300
uniprot id: A0A1B2HBI5
names: Similarity
messages: Belongs to the asparagine synthetase family.

1586287:BBK82 RS05465
gene id: 1586287:BBK82_RS05465
uniprot id: A0A1B2HD11
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1586287:BBK82 RS14500
gene id: 1586287:BBK82_RS14500
uniprot id: A0A1B2HH94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1586287:BBK82 RS15470
gene id: 1586287:BBK82_RS15470
uniprot id: A0A1B2HHR8
names: Caution
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS17165
gene id: 1586287:BBK82_RS17165
uniprot id: A0A1B2HYN1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1586287:BBK82 RS09655
gene id: 1586287:BBK82_RS09655
uniprot id: A0A1B2HEZ2
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1586287:BBK82 RS15505
gene id: 1586287:BBK82_RS15505
uniprot id: A0A1B2HHQ1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS04540
gene id: 1586287:BBK82_RS04540
uniprot id: A0A1B2HCP6
names: Similarity
messages: Belongs to the EspG family.

1586287:BBK82 RS14095
gene id: 1586287:BBK82_RS14095
uniprot id: A0A1B2HH32
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS08360
gene id: 1586287:BBK82_RS08360
uniprot id: A0A1B2HED5
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS19710
gene id: 1586287:BBK82_RS19710
uniprot id: A0A1B2HJT1
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS09925
gene id: 1586287:BBK82_RS09925
uniprot id: A0A1B2HF27
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS38915
gene id: 1586287:BBK82_RS38915
uniprot id: A0A1B2HTL6
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1586287:BBK82 RS19465
gene id: 1586287:BBK82_RS19465
uniprot id: A0A1B2HJL3
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1586287:BBK82 RS13575
gene id: 1586287:BBK82_RS13575
uniprot id: A0A1B2HGX1
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS44530
gene id: 1586287:BBK82_RS44530
uniprot id: A0A1B2HW46
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1586287:BBK82 RS03890
gene id: 1586287:BBK82_RS03890
uniprot id: A0A1B2HCA8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1586287:BBK82 RS06855
gene id: 1586287:BBK82_RS06855
uniprot id: A0A1B2HDP0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

1586287:BBK82 RS25280
gene id: 1586287:BBK82_RS25280
uniprot id: A0A1B2HMD0
names: Similarity
messages: Belongs to the DapA family.

1586287:BBK82 RS15580
gene id: 1586287:BBK82_RS15580
uniprot id: A0A1B2HHU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS02100
gene id: 1586287:BBK82_RS02100
uniprot id: A0A1B2HBF5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1586287:BBK82 RS15705
gene id: 1586287:BBK82_RS15705
uniprot id: A0A1B2HHT1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1586287:BBK82 RS30230
gene id: 1586287:BBK82_RS30230
uniprot id: A0A1B2HPM5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS28000
gene id: 1586287:BBK82_RS28000
uniprot id: A0A1B2HNM3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1586287:BBK82 RS17970
gene id: 1586287:BBK82_RS17970
uniprot id: A0A1B2HIX2
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

1586287:BBK82 RS30840
gene id: 1586287:BBK82_RS30840
uniprot id: A0A1B2HPY0
names: Similarity
messages: Belongs to the AHA1 family.

1586287:BBK82 RS25645
gene id: 1586287:BBK82_RS25645
uniprot id: A0A1B2HMK5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1586287:BBK82 RS23805
gene id: 1586287:BBK82_RS23805
uniprot id: A0A1B2HLQ2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1586287:BBK82 RS22190
gene id: 1586287:BBK82_RS22190
uniprot id: A0A1B2HKX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1586287:BBK82 RS37985
gene id: 1586287:BBK82_RS37985
uniprot id: A0A1B2HT97
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1586287:BBK82 RS09520
gene id: 1586287:BBK82_RS09520
uniprot id: A0A1B2HEX4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1586287:BBK82 RS18980
gene id: 1586287:BBK82_RS18980
uniprot id: A0A1B2HJE9
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1586287:BBK82 RS38825
gene id: 1586287:BBK82_RS38825
uniprot id: A0A1B2HTJ9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS07580
gene id: 1586287:BBK82_RS07580
uniprot id: A0A1B2HE05
names: Similarity
messages: Belongs to the asp23 family.

1586287:BBK82 RS45430
gene id: 1586287:BBK82_RS45430
uniprot id: A0A1B2HWM6
names: Similarity
messages: Belongs to the peptidase S1 family.

1586287:BBK82 RS00295
gene id: 1586287:BBK82_RS00295
uniprot id: A0A1B2HAL5
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

1586287:BBK82 RS14510
gene id: 1586287:BBK82_RS14510
uniprot id: A0A1B2HH87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1586287:BBK82 RS04625
gene id: 1586287:BBK82_RS04625
uniprot id: A0A1B2HCM7
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1586287:BBK82 RS04300
gene id: 1586287:BBK82_RS04300
uniprot id: A0A1B2HCH0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1586287:BBK82 RS45745
gene id: 1586287:BBK82_RS45745
uniprot id: A0A1B2I0T9
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1586287:BBK82 RS04700
gene id: 1586287:BBK82_RS04700
uniprot id: A0A1B2HCP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS23100
gene id: 1586287:BBK82_RS23100
uniprot id: A0A1B2HLB5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1586287:BBK82 RS17650
gene id: 1586287:BBK82_RS17650
uniprot id: A0A1B2HYL5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1586287:BBK82 RS12915
gene id: 1586287:BBK82_RS12915
uniprot id: A0A1B2HGI3
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS20965
gene id: 1586287:BBK82_RS20965
uniprot id: A0A1B2HKA8
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS24595
gene id: 1586287:BBK82_RS24595
uniprot id: A0A1B2HM45
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1586287:BBK82 RS13530
gene id: 1586287:BBK82_RS13530
uniprot id: A0A1B2HGV1
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

1586287:BBK82 RS14490
gene id: 1586287:BBK82_RS14490
uniprot id: A0A1B2HH92
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1586287:BBK82 RS20830
gene id: 1586287:BBK82_RS20830
uniprot id: A0A1B2HKA2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1586287:BBK82 RS14070
gene id: 1586287:BBK82_RS14070
uniprot id: A0A1B2HH45
names: Similarity
messages: Belongs to the cytochrome P450 family.

1586287:BBK82 RS22850
gene id: 1586287:BBK82_RS22850
uniprot id: A0A1B2HZ34
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS23420
gene id: 1586287:BBK82_RS23420
uniprot id: A0A1B2HLJ8
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Reversible hydration of carbon dioxide.

1586287:BBK82 RS17190
gene id: 1586287:BBK82_RS17190
uniprot id: A0A1B2HIH9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1586287:BBK82 RS22570
gene id: 1586287:BBK82_RS22570
uniprot id: A0A1B2HL40
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1586287:BBK82 RS17635
gene id: 1586287:BBK82_RS17635
uniprot id: A0A1B2HIQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1586287:BBK82 RS17615
gene id: 1586287:BBK82_RS17615
uniprot id: A0A1B2HIR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1586287:BBK82 RS16770
gene id: 1586287:BBK82_RS16770
uniprot id: A0A1B2HIA2
names: Cofactor
messages: Binds 1 FAD per subunit.

1586287:BBK82 RS27285
gene id: 1586287:BBK82_RS27285
uniprot id: A0A1B2HNB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. EgtD family.
messages: Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine.
messages: Monomer.

1586287:BBK82 RS46860
gene id: 1586287:BBK82_RS46860
uniprot id: A0A1B2HX56
names: Similarity
messages: Belongs to the IMPACT family.

1586287:BBK82 RS34490
gene id: 1586287:BBK82_RS34490
uniprot id: A0A1B2HRR2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS11840
gene id: 1586287:BBK82_RS11840
uniprot id: A0A1B2HG24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1586287:BBK82 RS34945
gene id: 1586287:BBK82_RS34945
uniprot id: A0A1B2HRT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS18515
gene id: 1586287:BBK82_RS18515
uniprot id: A0A1B2HJ57
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1586287:BBK82 RS14465
gene id: 1586287:BBK82_RS14465
uniprot id: A0A1B2HHB5
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS20755
gene id: 1586287:BBK82_RS20755
uniprot id: A0A1B2HK71
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1586287:BBK82 RS31005
gene id: 1586287:BBK82_RS31005
uniprot id: A0A1B2HQ34
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS14585
gene id: 1586287:BBK82_RS14585
uniprot id: A0A1B2HH95
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1586287:BBK82 RS21060
gene id: 1586287:BBK82_RS21060
uniprot id: A0A1B2HKG0
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS12525
gene id: 1586287:BBK82_RS12525
uniprot id: A0A1B2HGE0
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

1586287:BBK82 RS18785
gene id: 1586287:BBK82_RS18785
uniprot id: A0A1B2HJA6
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1586287:BBK82 RS19875
gene id: 1586287:BBK82_RS19875
uniprot id: A0A1B2HJT5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1586287:BBK82 RS36930
gene id: 1586287:BBK82_RS36930
uniprot id: A0A1B2HSR4
names: Similarity
messages: Belongs to the YciI family.

1586287:BBK82 RS17040
gene id: 1586287:BBK82_RS17040
uniprot id: A0A1B2HIF3
names: Similarity
messages: Belongs to the isochorismate synthase family.

1586287:BBK82 RS36745
gene id: 1586287:BBK82_RS36745
uniprot id: A0A1B2HSP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS42345
gene id: 1586287:BBK82_RS42345
uniprot id: A0A1B2HV62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS33740
gene id: 1586287:BBK82_RS33740
uniprot id: A0A1B2HR98
names: Similarity
messages: Belongs to the Fur family.

1586287:BBK82 RS36430
gene id: 1586287:BBK82_RS36430
uniprot id: A0A1B2HSH7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS11235
gene id: 1586287:BBK82_RS11235
uniprot id: A0A1B2HFS5
names: Similarity
messages: Belongs to the citrate synthase family.

1586287:BBK82 RS41990
gene id: 1586287:BBK82_RS41990
uniprot id: A0A1B2HV39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1586287:BBK82 RS45860
gene id: 1586287:BBK82_RS45860
uniprot id: A0A1B2HWT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1586287:BBK82 RS17665
gene id: 1586287:BBK82_RS17665
uniprot id: A0A1B2HIQ6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1586287:BBK82 RS38650
gene id: 1586287:BBK82_RS38650
uniprot id: A0A1B2I0A6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1586287:BBK82 RS31420
gene id: 1586287:BBK82_RS31420
uniprot id: A0A1B2HQA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

1586287:BBK82 RS06665
gene id: 1586287:BBK82_RS06665
uniprot id: A0A1B2HDK6
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1586287:BBK82 RS20215
gene id: 1586287:BBK82_RS20215
uniprot id: A0A1B2HJZ7
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1586287:BBK82 RS26875
gene id: 1586287:BBK82_RS26875
uniprot id: A0A1B2HN67
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1586287:BBK82 RS17585
gene id: 1586287:BBK82_RS17585
uniprot id: A0A1B2HIN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1586287:BBK82 RS27945
gene id: 1586287:BBK82_RS27945
uniprot id: A0A1B2HZF0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS40970
gene id: 1586287:BBK82_RS40970
uniprot id: A0A1B2HUN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS19075
gene id: 1586287:BBK82_RS19075
uniprot id: A0A1B2HJG2
names: Similarity
messages: Belongs to the AHA1 family.

1586287:BBK82 RS42215
gene id: 1586287:BBK82_RS42215
uniprot id: A0A1B2HV20
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1586287:BBK82 RS35895
gene id: 1586287:BBK82_RS35895
uniprot id: A0A1B2HS71
names: Similarity
messages: Belongs to the cytochrome P450 family.

1586287:BBK82 RS31940
gene id: 1586287:BBK82_RS31940
uniprot id: A0A1B2HZP7
names: Similarity
messages: Belongs to the FGGY kinase family.

1586287:BBK82 RS22710
gene id: 1586287:BBK82_RS22710
uniprot id: A0A1B2HL70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1586287:BBK82 RS25195
gene id: 1586287:BBK82_RS25195
uniprot id: A0A1B2HME1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1586287:BBK82 RS09770
gene id: 1586287:BBK82_RS09770
uniprot id: A0A1B2HY07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS30000
gene id: 1586287:BBK82_RS30000
uniprot id: A0A1B2HPI0
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

1586287:BBK82 RS38810
gene id: 1586287:BBK82_RS38810
uniprot id: A0A1B2HTN1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1586287:BBK82 RS24545
gene id: 1586287:BBK82_RS24545
uniprot id: A0A1B2HM06
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1586287:BBK82 RS39570
gene id: 1586287:BBK82_RS39570
uniprot id: A0A1B2HTY5
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS47110
gene id: 1586287:BBK82_RS47110
uniprot id: A0A1B2HX85
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1586287:BBK82 RS17820
gene id: 1586287:BBK82_RS17820
uniprot id: A0A1B2HYQ4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1586287:BBK82 RS02785
gene id: 1586287:BBK82_RS02785
uniprot id: A0A1B2HBR1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1586287:BBK82 RS00220
gene id: 1586287:BBK82_RS00220
uniprot id: A0A1B2HAJ0
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS31870
gene id: 1586287:BBK82_RS31870
uniprot id: A0A1B2HQJ0
names: Similarity
messages: Belongs to the mycobacterial PPE family.

1586287:BBK82 RS22195
gene id: 1586287:BBK82_RS22195
uniprot id: A0A1B2HKZ2
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS10365
gene id: 1586287:BBK82_RS10365
uniprot id: A0A1B2HFC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

1586287:BBK82 RS29020
gene id: 1586287:BBK82_RS29020
uniprot id: A0A1B2HP50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS28950
gene id: 1586287:BBK82_RS28950
uniprot id: A0A1B2HP37
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS38990
gene id: 1586287:BBK82_RS38990
uniprot id: A0A1B2HTS2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1586287:BBK82 RS24680
gene id: 1586287:BBK82_RS24680
uniprot id: A0A1B2HM58
names: Similarity
messages: Belongs to the TlyA family.

1586287:BBK82 RS39535
gene id: 1586287:BBK82_RS39535
uniprot id: A0A1B2I077
names: Similarity
messages: Belongs to the ribulokinase family.

1586287:BBK82 RS02560
gene id: 1586287:BBK82_RS02560
uniprot id: A0A1B2HBQ5
names: Similarity
messages: Belongs to the cytochrome P450 family.

1586287:BBK82 RS40720
gene id: 1586287:BBK82_RS40720
uniprot id: A0A1B2HUE5
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS46345
gene id: 1586287:BBK82_RS46345
uniprot id: A0A1B2I0S1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1586287:BBK82 RS32660
gene id: 1586287:BBK82_RS32660
uniprot id: A0A1B2HQS8
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1586287:BBK82 RS32355
gene id: 1586287:BBK82_RS32355
uniprot id: A0A1B2HZQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1586287:BBK82 RS21630
gene id: 1586287:BBK82_RS21630
uniprot id: A0A1B2HKM4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1586287:BBK82 RS22405
gene id: 1586287:BBK82_RS22405
uniprot id: A0A1B2HL01
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1586287:BBK82 RS05540
gene id: 1586287:BBK82_RS05540
uniprot id: A0A1B2HD26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1586287:BBK82 RS44690
gene id: 1586287:BBK82_RS44690
uniprot id: A0A1B2HWC2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1586287:BBK82 RS34800
gene id: 1586287:BBK82_RS34800
uniprot id: A0A1B2HRV8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1586287:BBK82 RS33735
gene id: 1586287:BBK82_RS33735
uniprot id: A0A1B2HRA4
names: Similarity
messages: Belongs to the catalase family.

1586287:BBK82 RS41070
gene id: 1586287:BBK82_RS41070
uniprot id: A0A1B2HUJ3
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1586287:BBK82 RS17670
gene id: 1586287:BBK82_RS17670
uniprot id: A0A1B2HIR4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1586287:BBK82 RS21585
gene id: 1586287:BBK82_RS21585
uniprot id: A0A1B2HKP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1586287:BBK82 RS15380
gene id: 1586287:BBK82_RS15380
uniprot id: A0A1B2HHN4
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS18915
gene id: 1586287:BBK82_RS18915
uniprot id: A0A1B2HJD0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1586287:BBK82 RS01165
gene id: 1586287:BBK82_RS01165
uniprot id: A0A1B2HAZ2
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

1586287:BBK82 RS25335
gene id: 1586287:BBK82_RS25335
uniprot id: A0A1B2HMH5
names: Similarity
messages: Belongs to the TPP enzyme family.

1586287:BBK82 RS27255
gene id: 1586287:BBK82_RS27255
uniprot id: A0A1B2HNC8
names: Similarity
messages: Belongs to the cytochrome P450 family.

1586287:BBK82 RS37110
gene id: 1586287:BBK82_RS37110
uniprot id: A0A1B2HSR0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS27110
gene id: 1586287:BBK82_RS27110
uniprot id: A0A1B2HNB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1586287:BBK82 RS28435
gene id: 1586287:BBK82_RS28435
uniprot id: A0A1B2HNV1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1586287:BBK82 RS16220
gene id: 1586287:BBK82_RS16220
uniprot id: A0A1B2HI39
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1586287:BBK82 RS25990
gene id: 1586287:BBK82_RS25990
uniprot id: A0A1B2HMR6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS13655
gene id: 1586287:BBK82_RS13655
uniprot id: A0A1B2HGY9
names: Similarity
messages: Belongs to the peptidase M28 family. M28A subfamily.

1586287:BBK82 RS01395
gene id: 1586287:BBK82_RS01395
uniprot id: A0A1B2HB38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1586287:BBK82 RS15150
gene id: 1586287:BBK82_RS15150
uniprot id: A0A1B2HHK5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1586287:BBK82 RS38025
gene id: 1586287:BBK82_RS38025
uniprot id: A0A1B2HT57
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS39405
gene id: 1586287:BBK82_RS39405
uniprot id: A0A1B2HTX4
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

1586287:BBK82 RS32390
gene id: 1586287:BBK82_RS32390
uniprot id: A0A1B2HQR4
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1586287:BBK82 RS37510
gene id: 1586287:BBK82_RS37510
uniprot id: A0A1B2HSY2
names: Similarity
messages: Belongs to the peptidase S8 family.

1586287:BBK82 RS28025
gene id: 1586287:BBK82_RS28025
uniprot id: A0A1B2HNN5
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1586287:BBK82 RS10425
gene id: 1586287:BBK82_RS10425
uniprot id: A0A1B2HFE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1586287:BBK82 RS19440
gene id: 1586287:BBK82_RS19440
uniprot id: A0A1B2HJJ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1586287:BBK82 RS01785
gene id: 1586287:BBK82_RS01785
uniprot id: A0A1B2HBB2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1586287:BBK82 RS46640
gene id: 1586287:BBK82_RS46640
uniprot id: A0A1B2HX71
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS22000
gene id: 1586287:BBK82_RS22000
uniprot id: A0A1B2HKW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

1586287:BBK82 RS33850
gene id: 1586287:BBK82_RS33850
uniprot id: A0A1B2HRB0
names: Similarity
messages: Belongs to the cytochrome P450 family.

1586287:BBK82 RS02375
gene id: 1586287:BBK82_RS02375
uniprot id: A0A1B2HXL7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1586287:BBK82 RS25100
gene id: 1586287:BBK82_RS25100
uniprot id: A0A1B2HM95
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS22335
gene id: 1586287:BBK82_RS22335
uniprot id: A0A1B2HKY8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1586287:BBK82 RS03765
gene id: 1586287:BBK82_RS03765
uniprot id: A0A1B2HC94
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1586287:BBK82 RS12580
gene id: 1586287:BBK82_RS12580
uniprot id: A0A1B2HGF0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1586287:BBK82 RS10505
gene id: 1586287:BBK82_RS10505
uniprot id: A0A1B2HF98
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

1586287:BBK82 RS45980
gene id: 1586287:BBK82_RS45980
uniprot id: A0A1B2HWT5
names: Similarity
messages: Belongs to the peptidase A24 family.

1586287:BBK82 RS34710
gene id: 1586287:BBK82_RS34710
uniprot id: A0A1B2HRQ0
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

1586287:BBK82 RS44495
gene id: 1586287:BBK82_RS44495
uniprot id: A0A1B2HW71
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS33530
gene id: 1586287:BBK82_RS33530
uniprot id: A0A1B2HR65
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS03915
gene id: 1586287:BBK82_RS03915
uniprot id: A0A1B2HCB1
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS32790
gene id: 1586287:BBK82_RS32790
uniprot id: A0A1B2HQY4
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1586287:BBK82 RS23850
gene id: 1586287:BBK82_RS23850
uniprot id: A0A1B2HLP3
names: Similarity
messages: Belongs to the TPP enzyme family.

1586287:BBK82 RS25535
gene id: 1586287:BBK82_RS25535
uniprot id: A0A1B2HMH1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS18520
gene id: 1586287:BBK82_RS18520
uniprot id: A0A1B2HJ55
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1586287:BBK82 RS25465
gene id: 1586287:BBK82_RS25465
uniprot id: A0A1B2HMH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1586287:BBK82 RS03920
gene id: 1586287:BBK82_RS03920
uniprot id: A0A1B2HCA5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1586287:BBK82 RS41550
gene id: 1586287:BBK82_RS41550
uniprot id: A0A1B2HUX9
names: Similarity
messages: Belongs to the peptidase S33 family.

1586287:BBK82 RS33180
gene id: 1586287:BBK82_RS33180
uniprot id: A0A1B2HR24
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS45750
gene id: 1586287:BBK82_RS45750
uniprot id: A0A1B2I0W1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1586287:BBK82 RS17675
gene id: 1586287:BBK82_RS17675
uniprot id: A0A1B2HIS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1586287:BBK82 RS19235
gene id: 1586287:BBK82_RS19235
uniprot id: A0A1B2HJI2
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS24255
gene id: 1586287:BBK82_RS24255
uniprot id: A0A1B2HLY8
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS46950
gene id: 1586287:BBK82_RS46950
uniprot id: A0A1B2HXC8
names: Similarity
messages: Belongs to the YciI family.

1586287:BBK82 RS00230
gene id: 1586287:BBK82_RS00230
uniprot id: A0A1B2HAJ3
names: Similarity
messages: Belongs to the cytochrome P450 family.

1586287:BBK82 RS43025
gene id: 1586287:BBK82_RS43025
uniprot id: A0A1B2HVH1
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1586287:BBK82 RS33565
gene id: 1586287:BBK82_RS33565
uniprot id: A0A1B2HR93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS19745
gene id: 1586287:BBK82_RS19745
uniprot id: A0A1B2HJR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

1586287:BBK82 RS37850
gene id: 1586287:BBK82_RS37850
uniprot id: A0A1B2HT36
names: Function
names: Similarity
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.

1586287:BBK82 RS30405
gene id: 1586287:BBK82_RS30405
uniprot id: A0A1B2HPQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS10135
gene id: 1586287:BBK82_RS10135
uniprot id: A0A1B2HF40
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

1586287:BBK82 RS20515
gene id: 1586287:BBK82_RS20515
uniprot id: A0A1B2HK81
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS39815
gene id: 1586287:BBK82_RS39815
uniprot id: A0A1B2HTZ8
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS28445
gene id: 1586287:BBK82_RS28445
uniprot id: A0A1B2HNX2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1586287:BBK82 RS24125
gene id: 1586287:BBK82_RS24125
uniprot id: A0A1B2HLU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1586287:BBK82 RS09720
gene id: 1586287:BBK82_RS09720
uniprot id: A0A1B2HF19
names: Similarity
messages: Belongs to the YciI family.

1586287:BBK82 RS22240
gene id: 1586287:BBK82_RS22240
uniprot id: A0A1B2HKZ3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1586287:BBK82 RS31155
gene id: 1586287:BBK82_RS31155
uniprot id: A0A1B2HQ39
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1586287:BBK82 RS15230
gene id: 1586287:BBK82_RS15230
uniprot id: A0A1B2HHN1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1586287:BBK82 RS17915
gene id: 1586287:BBK82_RS17915
uniprot id: A0A1B2HYQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1586287:BBK82 RS27675
gene id: 1586287:BBK82_RS27675
uniprot id: A0A1B2HNH2
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1586287:BBK82 RS27275
gene id: 1586287:BBK82_RS27275
uniprot id: A0A1B2HND4
names: Function
names: Similarity
messages: Belongs to the EgtB family.
messages: Catalyzes the oxidative sulfurization of hercynine (N-alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

1586287:BBK82 RS00445
gene id: 1586287:BBK82_RS00445
uniprot id: A0A1B2HAN3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1586287:BBK82 RS16010
gene id: 1586287:BBK82_RS16010
uniprot id: A0A1B2HI02
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1586287:BBK82 RS05310
gene id: 1586287:BBK82_RS05310
uniprot id: A0A1B2HCY4
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1586287:BBK82 RS30945
gene id: 1586287:BBK82_RS30945
uniprot id: A0A1B2HPZ9
names: Similarity
messages: Belongs to the cytochrome P450 family.

1586287:BBK82 RS19715
gene id: 1586287:BBK82_RS19715
uniprot id: A0A1B2HJS1
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

1586287:BBK82 RS16680
gene id: 1586287:BBK82_RS16680
uniprot id: A0A1B2HI95
names: Similarity
messages: Belongs to the peptidase S1 family.

1586287:BBK82 RS31810
gene id: 1586287:BBK82_RS31810
uniprot id: A0A1B2HQE9
names: Similarity
messages: Belongs to the peptidase S1 family.

1586287:BBK82 RS01840
gene id: 1586287:BBK82_RS01840
uniprot id: A0A1B2HBB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS14450
gene id: 1586287:BBK82_RS14450
uniprot id: A0A1B2HYA8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1586287:BBK82 RS39355
gene id: 1586287:BBK82_RS39355
uniprot id: A0A1B2HTV4
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS37180
gene id: 1586287:BBK82_RS37180
uniprot id: A0A1B2HSW8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1586287:BBK82 RS08875
gene id: 1586287:BBK82_RS08875
uniprot id: A0A1B2HEP1
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1586287:BBK82 RS05415
gene id: 1586287:BBK82_RS05415
uniprot id: A0A1B2HD10
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

1586287:BBK82 RS16435
gene id: 1586287:BBK82_RS16435
uniprot id: A0A1B2HI52
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1586287:BBK82 RS02015
gene id: 1586287:BBK82_RS02015
uniprot id: A0A1B2HBC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1586287:BBK82 RS21010
gene id: 1586287:BBK82_RS21010
uniprot id: A0A1B2HKD2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS27730
gene id: 1586287:BBK82_RS27730
uniprot id: A0A1B2HNJ7
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1586287:BBK82 RS21945
gene id: 1586287:BBK82_RS21945
uniprot id: A0A1B2HKS9
names: Similarity
messages: Belongs to the P(II) protein family.

1586287:BBK82 RS09975
gene id: 1586287:BBK82_RS09975
uniprot id: A0A1B2HF36
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1586287:BBK82 RS09915
gene id: 1586287:BBK82_RS09915
uniprot id: A0A1B2HF43
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1586287:BBK82 RS21080
gene id: 1586287:BBK82_RS21080
uniprot id: A0A1B2HYT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

1586287:BBK82 RS44335
gene id: 1586287:BBK82_RS44335
uniprot id: A0A1B2HW24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS08520
gene id: 1586287:BBK82_RS08520
uniprot id: A0A1B2HEF8
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS02940
gene id: 1586287:BBK82_RS02940
uniprot id: A0A1B2HXI2
names: Similarity
messages: Belongs to the cytochrome P450 family.

1586287:BBK82 RS33560
gene id: 1586287:BBK82_RS33560
uniprot id: A0A1B2HR72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS13220
gene id: 1586287:BBK82_RS13220
uniprot id: A0A1B2HGP6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS31625
gene id: 1586287:BBK82_RS31625
uniprot id: A0A1B2HQA5
names: Similarity
messages: Belongs to the thioredoxin family.

1586287:BBK82 RS22785
gene id: 1586287:BBK82_RS22785
uniprot id: A0A1B2HL71
names: Similarity
messages: Belongs to the PspA/IM30 family.

1586287:BBK82 RS08660
gene id: 1586287:BBK82_RS08660
uniprot id: A0A1B2HEI1
names: Similarity
messages: Belongs to the glutamine synthetase family.

1586287:BBK82 RS14445
gene id: 1586287:BBK82_RS14445
uniprot id: A0A1B2HH83
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS26970
gene id: 1586287:BBK82_RS26970
uniprot id: A0A1B2HN69
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1586287:BBK82 RS36605
gene id: 1586287:BBK82_RS36605
uniprot id: A0A1B2I000
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS32805
gene id: 1586287:BBK82_RS32805
uniprot id: A0A1B2HQW8
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1586287:BBK82 RS23830
gene id: 1586287:BBK82_RS23830
uniprot id: A0A1B2HLR7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1586287:BBK82 RS02640
gene id: 1586287:BBK82_RS02640
uniprot id: A0A1B2HBN0
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1586287:BBK82 RS05775
gene id: 1586287:BBK82_RS05775
uniprot id: A0A1B2HD57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1586287:BBK82 RS20580
gene id: 1586287:BBK82_RS20580
uniprot id: A0A1B2HK63
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1586287:BBK82 RS05855
gene id: 1586287:BBK82_RS05855
uniprot id: A0A1B2HD67
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1586287:BBK82 RS09835
gene id: 1586287:BBK82_RS09835
uniprot id: A0A1B2HF00
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1586287:BBK82 RS06345
gene id: 1586287:BBK82_RS06345
uniprot id: A0A1B2HDH5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1586287:BBK82 RS27640
gene id: 1586287:BBK82_RS27640
uniprot id: A0A1B2HNJ5
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS40050
gene id: 1586287:BBK82_RS40050
uniprot id: A0A1B2HU35
names: Similarity
messages: Belongs to the cytochrome P450 family.

1586287:BBK82 RS29400
gene id: 1586287:BBK82_RS29400
uniprot id: A0A1B2HPA8
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1586287:BBK82 RS32460
gene id: 1586287:BBK82_RS32460
uniprot id: A0A1B2HQR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS24485
gene id: 1586287:BBK82_RS24485
uniprot id: A0A1B2HM23
names: Similarity
messages: Belongs to the RutC family.

1586287:BBK82 RS39490
gene id: 1586287:BBK82_RS39490
uniprot id: A0A1B2HTW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS17600
gene id: 1586287:BBK82_RS17600
uniprot id: A0A1B2HIQ8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1586287:BBK82 RS00330
gene id: 1586287:BBK82_RS00330
uniprot id: A0A1B2HXG4
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1586287:BBK82 RS34195
gene id: 1586287:BBK82_RS34195
uniprot id: A0A1B2HRK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS14525
gene id: 1586287:BBK82_RS14525
uniprot id: A0A1B2HH89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1586287:BBK82 RS24610
gene id: 1586287:BBK82_RS24610
uniprot id: A0A1B2HM24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1586287:BBK82 RS22970
gene id: 1586287:BBK82_RS22970
uniprot id: A0A1B2HLA4
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS06845
gene id: 1586287:BBK82_RS06845
uniprot id: A0A1B2HDN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS37505
gene id: 1586287:BBK82_RS37505
uniprot id: A0A1B2HT14
names: Similarity
messages: Belongs to the peptidase S8 family.

1586287:BBK82 RS20680
gene id: 1586287:BBK82_RS20680
uniprot id: A0A1B2HK80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1586287:BBK82 RS02695
gene id: 1586287:BBK82_RS02695
uniprot id: A0A1B2HBN9
names: Similarity
messages: Belongs to the cytochrome P450 family.

1586287:BBK82 RS17000
gene id: 1586287:BBK82_RS17000
uniprot id: A0A1B2HIE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1586287:BBK82 RS09110
gene id: 1586287:BBK82_RS09110
uniprot id: A0A1B2HEP0
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

1586287:BBK82 RS05845
gene id: 1586287:BBK82_RS05845
uniprot id: A0A1B2HD92
names: Similarity
messages: Belongs to the cytochrome P450 family.

1586287:BBK82 RS32610
gene id: 1586287:BBK82_RS32610
uniprot id: A0A1B2HZM5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1586287:BBK82 RS12020
gene id: 1586287:BBK82_RS12020
uniprot id: A0A1B2HG45
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS23455
gene id: 1586287:BBK82_RS23455
uniprot id: A0A1B2HLH8
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

1586287:BBK82 RS25435
gene id: 1586287:BBK82_RS25435
uniprot id: A0A1B2HMF8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1586287:BBK82 RS23220
gene id: 1586287:BBK82_RS23220
uniprot id: A0A1B2HLF3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1586287:BBK82 RS09080
gene id: 1586287:BBK82_RS09080
uniprot id: A0A1B2HY09
names: Similarity
messages: Belongs to the cytochrome P450 family.

1586287:BBK82 RS41970
gene id: 1586287:BBK82_RS41970
uniprot id: A0A1B2HUY3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS22080
gene id: 1586287:BBK82_RS22080
uniprot id: A0A1B2HKW3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS22955
gene id: 1586287:BBK82_RS22955
uniprot id: A0A1B2HLA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1586287:BBK82 RS16445
gene id: 1586287:BBK82_RS16445
uniprot id: A0A1B2HI65
names: Subcellular Location Annotation
messages: Cytoplasm

1586287:BBK82 RS25650
gene id: 1586287:BBK82_RS25650
uniprot id: A0A1B2HMK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1586287:BBK82 RS27505
gene id: 1586287:BBK82_RS27505
uniprot id: A0A1B2HNF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1586287:BBK82 RS31950
gene id: 1586287:BBK82_RS31950
uniprot id: A0A1B2HQG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1586287:BBK82 RS11060
gene id: 1586287:BBK82_RS11060
uniprot id: A0A1B2HFN2
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1586287:BBK82 RS42040
gene id: 1586287:BBK82_RS42040
uniprot id: A0A1B2HV50
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

1586287:BBK82 RS45455
gene id: 1586287:BBK82_RS45455
uniprot id: A0A1B2I0P7
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1586287:BBK82 RS02905
gene id: 1586287:BBK82_RS02905
uniprot id: A0A1B2HBT0
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1586287:BBK82 RS33880
gene id: 1586287:BBK82_RS33880
uniprot id: A0A1B2HRE6
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1586287:BBK82 RS17185
gene id: 1586287:BBK82_RS17185
uniprot id: A0A1B2HIG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1586287:BBK82 RS17020
gene id: 1586287:BBK82_RS17020
uniprot id: A0A1B2HIF1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1586287:BBK82 RS29745
gene id: 1586287:BBK82_RS29745
uniprot id: A0A1B2HZJ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1586287:BBK82 RS28110
gene id: 1586287:BBK82_RS28110
uniprot id: A0A1B2HNM6
names: Similarity
messages: Belongs to the peptidase S8 family.

1586287:BBK82 RS06695
gene id: 1586287:BBK82_RS06695
uniprot id: A0A1B2HDL9
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1586287:BBK82 RS21675
gene id: 1586287:BBK82_RS21675
uniprot id: A0A1B2HKN9
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1586287:BBK82 RS18430
gene id: 1586287:BBK82_RS18430
uniprot id: A0A1B2HJ53
names: Similarity
messages: Belongs to the HepT RNase toxin family.

1586287:BBK82 RS09900
gene id: 1586287:BBK82_RS09900
uniprot id: A0A1B2HF12
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1586287:BBK82 RS21725
gene id: 1586287:BBK82_RS21725
uniprot id: A0A1B2HKR3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1586287:BBK82 RS31905
gene id: 1586287:BBK82_RS31905
uniprot id: A0A1B2HQH3
names: Similarity
messages: Belongs to the mycobacterial PPE family.

1586287:BBK82 RS45790
gene id: 1586287:BBK82_RS45790
uniprot id: A0A1B2I0X5
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1586287:BBK82 RS38060
gene id: 1586287:BBK82_RS38060
uniprot id: A0A1B2HT80
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1586287:BBK82 RS41805
gene id: 1586287:BBK82_RS41805
uniprot id: A0A1B2HV06
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1586287:BBK82 RS32455
gene id: 1586287:BBK82_RS32455
uniprot id: A0A1B2HQT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS35775
gene id: 1586287:BBK82_RS35775
uniprot id: A0A1B2HS83
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1586287:BBK82 RS20735
gene id: 1586287:BBK82_RS20735
uniprot id: A0A1B2HYX1
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1586287:BBK82 RS29390
gene id: 1586287:BBK82_RS29390
uniprot id: A0A1B2HP80
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS10470
gene id: 1586287:BBK82_RS10470
uniprot id: A0A1B2HY27
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1586287:BBK82 RS04135
gene id: 1586287:BBK82_RS04135
uniprot id: A0A1B2HCE8
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

1586287:BBK82 RS13110
gene id: 1586287:BBK82_RS13110
uniprot id: A0A1B2HGP3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1586287:BBK82 RS17630
gene id: 1586287:BBK82_RS17630
uniprot id: A0A1B2HIQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1586287:BBK82 RS41775
gene id: 1586287:BBK82_RS41775
uniprot id: A0A1B2HUU5
names: Similarity
messages: Belongs to the CDPS family.

1586287:BBK82 RS39410
gene id: 1586287:BBK82_RS39410
uniprot id: A0A1B2I0A0
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

1586287:BBK82 RS19795
gene id: 1586287:BBK82_RS19795
uniprot id: A0A1B2HJS6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1586287:BBK82 RS23390
gene id: 1586287:BBK82_RS23390
uniprot id: A0A1B2HLI3
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS22205
gene id: 1586287:BBK82_RS22205
uniprot id: A0A1B2HZ00
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1586287:BBK82 RS22040
gene id: 1586287:BBK82_RS22040
uniprot id: A0A1B2HKU8
names: Similarity
messages: Belongs to the UPF0102 family.

1586287:BBK82 RS05740
gene id: 1586287:BBK82_RS05740
uniprot id: A0A1B2HD54
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1586287:BBK82 RS44970
gene id: 1586287:BBK82_RS44970
uniprot id: A0A1B2HWD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1586287:BBK82 RS37380
gene id: 1586287:BBK82_RS37380
uniprot id: A0A1B2HSU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1586287:BBK82 RS21535
gene id: 1586287:BBK82_RS21535
uniprot id: A0A1B2HKP2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1586287:BBK82 RS22865
gene id: 1586287:BBK82_RS22865
uniprot id: A0A1B2HL97
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1586287:BBK82 RS02450
gene id: 1586287:BBK82_RS02450
uniprot id: A0A1B2HBN4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1586287:BBK82 RS11920
gene id: 1586287:BBK82_RS11920
uniprot id: A0A1B2HG03
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1586287:BBK82 RS23540
gene id: 1586287:BBK82_RS23540
uniprot id: A0A1B2HZ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS35560
gene id: 1586287:BBK82_RS35560
uniprot id: A0A1B2HS00
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1586287:BBK82 RS06250
gene id: 1586287:BBK82_RS06250
uniprot id: A0A1B2HDD1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1586287:BBK82 RS41150
gene id: 1586287:BBK82_RS41150
uniprot id: A0A1B2HUL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1586287:BBK82 RS07625
gene id: 1586287:BBK82_RS07625
uniprot id: A0A1B2HE19
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1586287:BBK82 RS20720
gene id: 1586287:BBK82_RS20720
uniprot id: A0A1B2HK78
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS00460
gene id: 1586287:BBK82_RS00460
uniprot id: A0A1B2HAM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.
messages: Membrane

1586287:BBK82 RS21460
gene id: 1586287:BBK82_RS21460
uniprot id: A0A1B2HYV7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1586287:BBK82 RS32720
gene id: 1586287:BBK82_RS32720
uniprot id: A0A1B2HQX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS05675
gene id: 1586287:BBK82_RS05675
uniprot id: A0A1B2HD61
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1586287:BBK82 RS18510
gene id: 1586287:BBK82_RS18510
uniprot id: A0A1B2HJ58
names: Similarity
messages: Belongs to the peptidase S11 family.

1586287:BBK82 RS20910
gene id: 1586287:BBK82_RS20910
uniprot id: A0A1B2HK99
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1586287:BBK82 RS17555
gene id: 1586287:BBK82_RS17555
uniprot id: A0A1B2HIP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1586287:BBK82 RS42675
gene id: 1586287:BBK82_RS42675
uniprot id: A0A1B2HVF8
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1586287:BBK82 RS22805
gene id: 1586287:BBK82_RS22805
uniprot id: A0A1B2HL87
names: Similarity
messages: Belongs to the cytochrome P450 family.

1586287:BBK82 RS14285
gene id: 1586287:BBK82_RS14285
uniprot id: A0A1B2HH77
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS19050
gene id: 1586287:BBK82_RS19050
uniprot id: A0A1B2HJE4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1586287:BBK82 RS17560
gene id: 1586287:BBK82_RS17560
uniprot id: A0A1B2HIP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1586287:BBK82 RS52265
gene id: 1586287:BBK82_RS52265
uniprot id: A0A1B2HDF6
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS09710
gene id: 1586287:BBK82_RS09710
uniprot id: A0A1B2HEZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1586287:BBK82 RS27180
gene id: 1586287:BBK82_RS27180
uniprot id: A0A1B2HZC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1586287:BBK82 RS32320
gene id: 1586287:BBK82_RS32320
uniprot id: A0A1B2HQM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1586287:BBK82 RS02130
gene id: 1586287:BBK82_RS02130
uniprot id: A0A1B2HBF0
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

1586287:BBK82 RS06420
gene id: 1586287:BBK82_RS06420
uniprot id: A0A1B2HDJ6
names: Similarity
messages: Belongs to the DszC flavin monooxygenase family.

1586287:BBK82 RS14515
gene id: 1586287:BBK82_RS14515
uniprot id: A0A1B2HHB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1586287:BBK82 RS23640
gene id: 1586287:BBK82_RS23640
uniprot id: A0A1B2HLM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1586287:BBK82 RS38335
gene id: 1586287:BBK82_RS38335
uniprot id: A0A1B2HTC9
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1586287:BBK82 RS39505
gene id: 1586287:BBK82_RS39505
uniprot id: A0A1B2HTV5
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS46625
gene id: 1586287:BBK82_RS46625
uniprot id: A0A1B2HX77
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS02220
gene id: 1586287:BBK82_RS02220
uniprot id: A0A1B2HBH9
names: Similarity
messages: Belongs to the peptidase C40 family.

1586287:BBK82 RS29715
gene id: 1586287:BBK82_RS29715
uniprot id: A0A1B2HPD7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1586287:BBK82 RS12235
gene id: 1586287:BBK82_RS12235
uniprot id: A0A1B2HG84
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

1586287:BBK82 RS08165
gene id: 1586287:BBK82_RS08165
uniprot id: A0A1B2HEC4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS40580
gene id: 1586287:BBK82_RS40580
uniprot id: A0A1B2HUB4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1586287:BBK82 RS15900
gene id: 1586287:BBK82_RS15900
uniprot id: A0A1B2HHW5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1586287:BBK82 RS39150
gene id: 1586287:BBK82_RS39150
uniprot id: A0A1B2HTU6
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS27020
gene id: 1586287:BBK82_RS27020
uniprot id: A0A1B2HNA8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1586287:BBK82 RS08670
gene id: 1586287:BBK82_RS08670
uniprot id: A0A1B2HEH8
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS10940
gene id: 1586287:BBK82_RS10940
uniprot id: A0A1B2HY70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1586287:BBK82 RS35575
gene id: 1586287:BBK82_RS35575
uniprot id: A0A1B2HS37
names: Similarity
messages: Belongs to the thioesterase family.

1586287:BBK82 RS01640
gene id: 1586287:BBK82_RS01640
uniprot id: A0A1B2HB68
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1586287:BBK82 RS50350
gene id: 1586287:BBK82_RS50350
uniprot id: A0A1B2HJF3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS14100
gene id: 1586287:BBK82_RS14100
uniprot id: A0A1B2HH51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1586287:BBK82 RS21855
gene id: 1586287:BBK82_RS21855
uniprot id: A0A1B2HKR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1586287:BBK82 RS42385
gene id: 1586287:BBK82_RS42385
uniprot id: A0A1B2HV88
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1586287:BBK82 RS46430
gene id: 1586287:BBK82_RS46430
uniprot id: A0A1B2HX31
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS15640
gene id: 1586287:BBK82_RS15640
uniprot id: A0A1B2HHS1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS30605
gene id: 1586287:BBK82_RS30605
uniprot id: A0A1B2HPU9
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1586287:BBK82 RS11460
gene id: 1586287:BBK82_RS11460
uniprot id: A0A1B2HFW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1586287:BBK82 RS17255
gene id: 1586287:BBK82_RS17255
uniprot id: A0A1B2HIJ7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS22800
gene id: 1586287:BBK82_RS22800
uniprot id: A0A1B2HL88
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1586287:BBK82 RS11455
gene id: 1586287:BBK82_RS11455
uniprot id: A0A1B2HFW1
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1586287:BBK82 RS17550
gene id: 1586287:BBK82_RS17550
uniprot id: A0A1B2HIQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1586287:BBK82 RS14745
gene id: 1586287:BBK82_RS14745
uniprot id: A0A1B2HHD5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

1586287:BBK82 RS13225
gene id: 1586287:BBK82_RS13225
uniprot id: A0A1B2HGP8
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

1586287:BBK82 RS26260
gene id: 1586287:BBK82_RS26260
uniprot id: A0A1B2HMX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1586287:BBK82 RS13775
gene id: 1586287:BBK82_RS13775
uniprot id: A0A1B2HGY8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1586287:BBK82 RS10055
gene id: 1586287:BBK82_RS10055
uniprot id: A0A1B2HF51
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1586287:BBK82 RS18465
gene id: 1586287:BBK82_RS18465
uniprot id: A0A1B2HJ45
names: Function
names: Similarity
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: In the C-terminal section; belongs to the radical SAM superfamily. CofH family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. CofG family.

1586287:BBK82 RS18850
gene id: 1586287:BBK82_RS18850
uniprot id: A0A1B2HJB7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1586287:BBK82 RS11690
gene id: 1586287:BBK82_RS11690
uniprot id: A0A1B2HFZ8
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

1586287:BBK82 RS15825
gene id: 1586287:BBK82_RS15825
uniprot id: A0A1B2HHV8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS38655
gene id: 1586287:BBK82_RS38655
uniprot id: A0A1B2HTI3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1586287:BBK82 RS18950
gene id: 1586287:BBK82_RS18950
uniprot id: A0A1B2HJE1
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1586287:BBK82 RS33550
gene id: 1586287:BBK82_RS33550
uniprot id: A0A1B2HR92
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1586287:BBK82 RS07970
gene id: 1586287:BBK82_RS07970
uniprot id: A0A1B2HE73
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1586287:BBK82 RS08510
gene id: 1586287:BBK82_RS08510
uniprot id: A0A1B2HEF7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1586287:BBK82 RS22025
gene id: 1586287:BBK82_RS22025
uniprot id: A0A1B2HKV4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1586287:BBK82 RS20360
gene id: 1586287:BBK82_RS20360
uniprot id: A0A1B2HK15
names: Similarity
messages: Belongs to the Vsr family.

1586287:BBK82 RS17875
gene id: 1586287:BBK82_RS17875
uniprot id: A0A1B2HYP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

1586287:BBK82 RS33370
gene id: 1586287:BBK82_RS33370
uniprot id: A0A1B2HR30
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS10120
gene id: 1586287:BBK82_RS10120
uniprot id: A0A1B2HF90
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

1586287:BBK82 RS21025
gene id: 1586287:BBK82_RS21025
uniprot id: A0A1B2HKB8
names: Similarity
messages: Belongs to the UPF0045 family.

1586287:BBK82 RS41100
gene id: 1586287:BBK82_RS41100
uniprot id: A0A1B2HUQ9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1586287:BBK82 RS21045
gene id: 1586287:BBK82_RS21045
uniprot id: A0A1B2HKC6
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS38895
gene id: 1586287:BBK82_RS38895
uniprot id: A0A1B2HTP7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1586287:BBK82 RS25000
gene id: 1586287:BBK82_RS25000
uniprot id: A0A1B2HM91
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1586287:BBK82 RS25980
gene id: 1586287:BBK82_RS25980
uniprot id: A0A1B2HMP8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS20915
gene id: 1586287:BBK82_RS20915
uniprot id: A0A1B2HKB7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1586287:BBK82 RS02885
gene id: 1586287:BBK82_RS02885
uniprot id: A0A1B2HBR9
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS21075
gene id: 1586287:BBK82_RS21075
uniprot id: A0A1B2HYU3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

1586287:BBK82 RS24905
gene id: 1586287:BBK82_RS24905
uniprot id: A0A1B2HM68
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1586287:BBK82 RS23350
gene id: 1586287:BBK82_RS23350
uniprot id: A0A1B2HLH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1586287:BBK82 RS20585
gene id: 1586287:BBK82_RS20585
uniprot id: A0A1B2HK74
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1586287:BBK82 RS29475
gene id: 1586287:BBK82_RS29475
uniprot id: A0A1B2HPC1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1586287:BBK82 RS01030
gene id: 1586287:BBK82_RS01030
uniprot id: A0A1B2HAX7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS16455
gene id: 1586287:BBK82_RS16455
uniprot id: A0A1B2HI72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1586287:BBK82 RS02255
gene id: 1586287:BBK82_RS02255
uniprot id: A0A1B2HBG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

1586287:BBK82 RS10435
gene id: 1586287:BBK82_RS10435
uniprot id: A0A1B2HFE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1586287:BBK82 RS11985
gene id: 1586287:BBK82_RS11985
uniprot id: A0A1B2HG49
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS11970
gene id: 1586287:BBK82_RS11970
uniprot id: A0A1B2HG31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1586287:BBK82 RS39620
gene id: 1586287:BBK82_RS39620
uniprot id: A0A1B2HTY1
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

1586287:BBK82 RS44830
gene id: 1586287:BBK82_RS44830
uniprot id: A0A1B2HWE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS29730
gene id: 1586287:BBK82_RS29730
uniprot id: A0A1B2HPI7
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1586287:BBK82 RS05940
gene id: 1586287:BBK82_RS05940
uniprot id: A0A1B2HDA8
names: Subcellular Location Annotation
messages: Cytoplasm

1586287:BBK82 RS04185
gene id: 1586287:BBK82_RS04185
uniprot id: A0A1B2HCF3
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1586287:BBK82 RS00065
gene id: 1586287:BBK82_RS00065
uniprot id: A0A1B2HXD1
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1586287:BBK82 RS00525
gene id: 1586287:BBK82_RS00525
uniprot id: A0A1B2HAN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1586287:BBK82 RS18865
gene id: 1586287:BBK82_RS18865
uniprot id: A0A1B2HJB4
names: Similarity
messages: Belongs to the mycobacterial PPE family.

1586287:BBK82 RS04015
gene id: 1586287:BBK82_RS04015
uniprot id: A0A1B2HCB9
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1586287:BBK82 RS01100
gene id: 1586287:BBK82_RS01100
uniprot id: A0A1B2HAY0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1586287:BBK82 RS07930
gene id: 1586287:BBK82_RS07930
uniprot id: A0A1B2HE54
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1586287:BBK82 RS25110
gene id: 1586287:BBK82_RS25110
uniprot id: A0A1B2HMB4
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1586287:BBK82 RS14830
gene id: 1586287:BBK82_RS14830
uniprot id: A0A1B2HHG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1586287:BBK82 RS11000
gene id: 1586287:BBK82_RS11000
uniprot id: A0A1B2HY80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1586287:BBK82 RS14110
gene id: 1586287:BBK82_RS14110
uniprot id: A0A1B2HH41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1586287:BBK82 RS31380
gene id: 1586287:BBK82_RS31380
uniprot id: A0A1B2HQ78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS26005
gene id: 1586287:BBK82_RS26005
uniprot id: A0A1B2HZ79
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1586287:BBK82 RS54115
gene id: 1586287:BBK82_RS54115
uniprot id: A0A1B2HI21
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS05710
gene id: 1586287:BBK82_RS05710
uniprot id: A0A1B2HD33
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1586287:BBK82 RS37520
gene id: 1586287:BBK82_RS37520
uniprot id: A0A1B2HT01
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

1586287:BBK82 RS44150
gene id: 1586287:BBK82_RS44150
uniprot id: A0A1B2HVX7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1586287:BBK82 RS12325
gene id: 1586287:BBK82_RS12325
uniprot id: A0A1B2HG87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS07745
gene id: 1586287:BBK82_RS07745
uniprot id: A0A1B2HE47
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1586287:BBK82 RS40195
gene id: 1586287:BBK82_RS40195
uniprot id: A0A1B2HUB2
names: Similarity
messages: Belongs to the peptidase S8 family.

1586287:BBK82 RS14650
gene id: 1586287:BBK82_RS14650
uniprot id: A0A1B2HHB9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS02570
gene id: 1586287:BBK82_RS02570
uniprot id: A0A1B2HBL7
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS10315
gene id: 1586287:BBK82_RS10315
uniprot id: A0A1B2HFB5
names: Similarity
messages: Belongs to the UPF0098 family.

1586287:BBK82 RS18800
gene id: 1586287:BBK82_RS18800
uniprot id: A0A1B2HJA4
names: Similarity
messages: Belongs to the peptidase M20A family.

1586287:BBK82 RS20185
gene id: 1586287:BBK82_RS20185
uniprot id: A0A1B2HJZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1586287:BBK82 RS12380
gene id: 1586287:BBK82_RS12380
uniprot id: A0A1B2HGC1
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

1586287:BBK82 RS00745
gene id: 1586287:BBK82_RS00745
uniprot id: A0A1B2HAT2
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS22160
gene id: 1586287:BBK82_RS22160
uniprot id: A0A1B2HKX7
names: Similarity
messages: Belongs to the cytochrome P450 family.

1586287:BBK82 RS23855
gene id: 1586287:BBK82_RS23855
uniprot id: A0A1B2HZ44
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS14530
gene id: 1586287:BBK82_RS14530
uniprot id: A0A1B2HHA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1586287:BBK82 RS42505
gene id: 1586287:BBK82_RS42505
uniprot id: A0A1B2HVB7
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS20335
gene id: 1586287:BBK82_RS20335
uniprot id: A0A1B2HK00
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

1586287:BBK82 RS22055
gene id: 1586287:BBK82_RS22055
uniprot id: A0A1B2HKX1
names: Similarity
messages: Belongs to the DprA/Smf family.

1586287:BBK82 RS04645
gene id: 1586287:BBK82_RS04645
uniprot id: A0A1B2HCL5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1586287:BBK82 RS18110
gene id: 1586287:BBK82_RS18110
uniprot id: A0A1B2HYQ9
names: Similarity
messages: Belongs to the histone deacetylase family.

1586287:BBK82 RS38745
gene id: 1586287:BBK82_RS38745
uniprot id: A0A1B2HTH6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1586287:BBK82 RS17025
gene id: 1586287:BBK82_RS17025
uniprot id: A0A1B2HIF9
names: Similarity
messages: Belongs to the peptidase M1 family.

1586287:BBK82 RS09785
gene id: 1586287:BBK82_RS09785
uniprot id: A0A1B2HF08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1586287:BBK82 RS07030
gene id: 1586287:BBK82_RS07030
uniprot id: A0A1B2HDT8
names: Subcellular Location Annotation
messages: Cytoplasm

1586287:BBK82 RS00440
gene id: 1586287:BBK82_RS00440
uniprot id: A0A1B2HAM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS17350
gene id: 1586287:BBK82_RS17350
uniprot id: A0A1B2HIK5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1586287:BBK82 RS17790
gene id: 1586287:BBK82_RS17790
uniprot id: A0A1B2HIR9
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1586287:BBK82 RS01455
gene id: 1586287:BBK82_RS01455
uniprot id: A0A1B2HB48
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

1586287:BBK82 RS18610
gene id: 1586287:BBK82_RS18610
uniprot id: A0A1B2HJ98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

1586287:BBK82 RS25930
gene id: 1586287:BBK82_RS25930
uniprot id: A0A1B2HMQ8
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS17120
gene id: 1586287:BBK82_RS17120
uniprot id: A0A1B2HIG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1586287:BBK82 RS30090
gene id: 1586287:BBK82_RS30090
uniprot id: A0A1B2HPL5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1586287:BBK82 RS03955
gene id: 1586287:BBK82_RS03955
uniprot id: A0A1B2HCA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1586287:BBK82 RS27010
gene id: 1586287:BBK82_RS27010
uniprot id: A0A1B2HN93
names: Similarity
messages: Belongs to the glutamine synthetase family.

1586287:BBK82 RS43120
gene id: 1586287:BBK82_RS43120
uniprot id: A0A1B2HVH5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS24570
gene id: 1586287:BBK82_RS24570
uniprot id: A0A1B2HM31
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1586287:BBK82 RS13630
gene id: 1586287:BBK82_RS13630
uniprot id: A0A1B2HGV5
names: Similarity
messages: Belongs to the CutA family.

1586287:BBK82 RS39910
gene id: 1586287:BBK82_RS39910
uniprot id: A0A1B2I0B2
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS01225
gene id: 1586287:BBK82_RS01225
uniprot id: A0A1B2HB01
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1586287:BBK82 RS05925
gene id: 1586287:BBK82_RS05925
uniprot id: A0A1B2HDD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS04410
gene id: 1586287:BBK82_RS04410
uniprot id: A0A1B2HXQ4
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS23130
gene id: 1586287:BBK82_RS23130
uniprot id: A0A1B2HLC1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS17805
gene id: 1586287:BBK82_RS17805
uniprot id: A0A1B2HIU1
names: Similarity
messages: Belongs to the WXG100 family.

1586287:BBK82 RS12610
gene id: 1586287:BBK82_RS12610
uniprot id: A0A1B2HGE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1586287:BBK82 RS15710
gene id: 1586287:BBK82_RS15710
uniprot id: A0A1B2HHU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS17640
gene id: 1586287:BBK82_RS17640
uniprot id: A0A1B2HIT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1586287:BBK82 RS35010
gene id: 1586287:BBK82_RS35010
uniprot id: A0A1B2HRU3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1586287:BBK82 RS18365
gene id: 1586287:BBK82_RS18365
uniprot id: A0A1B2HJ20
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1586287:BBK82 RS12275
gene id: 1586287:BBK82_RS12275
uniprot id: A0A1B2HG92
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS06400
gene id: 1586287:BBK82_RS06400
uniprot id: A0A1B2HDI0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

1586287:BBK82 RS17745
gene id: 1586287:BBK82_RS17745
uniprot id: A0A1B2HIS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS40280
gene id: 1586287:BBK82_RS40280
uniprot id: A0A1B2HU76
names: Similarity
messages: Belongs to the universal stress protein A family.

1586287:BBK82 RS32370
gene id: 1586287:BBK82_RS32370
uniprot id: A0A1B2HQP1
names: Similarity
messages: Belongs to the ketopantoate reductase family.

1586287:BBK82 RS22005
gene id: 1586287:BBK82_RS22005
uniprot id: A0A1B2HKT5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1586287:BBK82 RS25875
gene id: 1586287:BBK82_RS25875
uniprot id: A0A1B2HMM7
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1586287:BBK82 RS10890
gene id: 1586287:BBK82_RS10890
uniprot id: A0A1B2HFL7
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

1586287:BBK82 RS20295
gene id: 1586287:BBK82_RS20295
uniprot id: A0A1B2HK32
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1586287:BBK82 RS34225
gene id: 1586287:BBK82_RS34225
uniprot id: A0A1B2HRI3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1586287:BBK82 RS24935
gene id: 1586287:BBK82_RS24935
uniprot id: A0A1B2HM84
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS17730
gene id: 1586287:BBK82_RS17730
uniprot id: A0A1B2HIR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccB family.
messages: Membrane

1586287:BBK82 RS06540
gene id: 1586287:BBK82_RS06540
uniprot id: A0A1B2HDK9
names: Similarity
messages: Belongs to the terpene synthase family.

1586287:BBK82 RS39035
gene id: 1586287:BBK82_RS39035
uniprot id: A0A1B2HTS9
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

1586287:BBK82 RS02675
gene id: 1586287:BBK82_RS02675
uniprot id: A0A1B2HXK9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1586287:BBK82 RS12220
gene id: 1586287:BBK82_RS12220
uniprot id: A0A1B2HG77
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1586287:BBK82 RS27225
gene id: 1586287:BBK82_RS27225
uniprot id: A0A1B2HZB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1586287:BBK82 RS41620
gene id: 1586287:BBK82_RS41620
uniprot id: A0A1B2HUX8
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

1586287:BBK82 RS24305
gene id: 1586287:BBK82_RS24305
uniprot id: A0A1B2HLX2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1586287:BBK82 RS27515
gene id: 1586287:BBK82_RS27515
uniprot id: A0A1B2HNI0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1586287:BBK82 RS30835
gene id: 1586287:BBK82_RS30835
uniprot id: A0A1B2HPZ7
names: Similarity
messages: Belongs to the AHA1 family.

1586287:BBK82 RS22430
gene id: 1586287:BBK82_RS22430
uniprot id: A0A1B2HL03
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1586287:BBK82 RS08500
gene id: 1586287:BBK82_RS08500
uniprot id: A0A1B2HEG3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: Nucleus
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1586287:BBK82 RS09115
gene id: 1586287:BBK82_RS09115
uniprot id: A0A1B2HEP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1586287:BBK82 RS26330
gene id: 1586287:BBK82_RS26330
uniprot id: A0A1B2HMX4
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1586287:BBK82 RS21615
gene id: 1586287:BBK82_RS21615
uniprot id: A0A1B2HKM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1586287:BBK82 RS20660
gene id: 1586287:BBK82_RS20660
uniprot id: A0A1B2HK67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1586287:BBK82 RS22635
gene id: 1586287:BBK82_RS22635
uniprot id: A0A1B2HL39
names: Similarity
messages: Belongs to the AHA1 family.

1586287:BBK82 RS23115
gene id: 1586287:BBK82_RS23115
uniprot id: A0A1B2HLC6
names: Similarity
messages: Belongs to the cytochrome P450 family.

1586287:BBK82 RS06485
gene id: 1586287:BBK82_RS06485
uniprot id: A0A1B2HDH4
names: Similarity
messages: Belongs to the SurE nucleotidase family.

1586287:BBK82 RS17480
gene id: 1586287:BBK82_RS17480
uniprot id: A0A1B2HIM8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1586287:BBK82 RS11820
gene id: 1586287:BBK82_RS11820
uniprot id: A0A1B2HG13
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS45905
gene id: 1586287:BBK82_RS45905
uniprot id: A0A1B2HWV6
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1586287:BBK82 RS00925
gene id: 1586287:BBK82_RS00925
uniprot id: A0A1B2HAV9
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

1586287:BBK82 RS13580
gene id: 1586287:BBK82_RS13580
uniprot id: A0A1B2HGV4
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1586287:BBK82 RS24860
gene id: 1586287:BBK82_RS24860
uniprot id: A0A1B2HM62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS22275
gene id: 1586287:BBK82_RS22275
uniprot id: A0A1B2HL07
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1586287:BBK82 RS20000
gene id: 1586287:BBK82_RS20000
uniprot id: A0A1B2HJW5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1586287:BBK82 RS05980
gene id: 1586287:BBK82_RS05980
uniprot id: A0A1B2HDD9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1586287:BBK82 RS38725
gene id: 1586287:BBK82_RS38725
uniprot id: A0A1B2HTH8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1586287:BBK82 RS42440
gene id: 1586287:BBK82_RS42440
uniprot id: A0A1B2HVA7
names: Similarity
messages: Belongs to the manganese catalase family.

1586287:BBK82 RS02995
gene id: 1586287:BBK82_RS02995
uniprot id: A0A1B2HBT2
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1586287:BBK82 RS46175
gene id: 1586287:BBK82_RS46175
uniprot id: A0A1B2HX05
names: Similarity
messages: Belongs to the group II decarboxylase family.

1586287:BBK82 RS15355
gene id: 1586287:BBK82_RS15355
uniprot id: A0A1B2HHN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1586287:BBK82 RS38855
gene id: 1586287:BBK82_RS38855
uniprot id: A0A1B2HTK3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1586287:BBK82 RS08015
gene id: 1586287:BBK82_RS08015
uniprot id: A0A1B2HE93
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1586287:BBK82 RS46675
gene id: 1586287:BBK82_RS46675
uniprot id: A0A1B2I0V9
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

1586287:BBK82 RS15850
gene id: 1586287:BBK82_RS15850
uniprot id: A0A1B2HHX1
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1586287:BBK82 RS42275
gene id: 1586287:BBK82_RS42275
uniprot id: A0A1B2HV27
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1586287:BBK82 RS21485
gene id: 1586287:BBK82_RS21485
uniprot id: A0A1B2HKK4
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1586287:BBK82 RS39980
gene id: 1586287:BBK82_RS39980
uniprot id: A0A1B2HU50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS11350
gene id: 1586287:BBK82_RS11350
uniprot id: A0A1B2HFU6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS45435
gene id: 1586287:BBK82_RS45435
uniprot id: A0A1B2HWM2
names: Similarity
messages: Belongs to the peptidase S8 family.

1586287:BBK82 RS20670
gene id: 1586287:BBK82_RS20670
uniprot id: A0A1B2HK68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1586287:BBK82 RS03815
gene id: 1586287:BBK82_RS03815
uniprot id: A0A1B2HC86
names: Similarity
messages: Belongs to the peptidase S51 family.

1586287:BBK82 RS01295
gene id: 1586287:BBK82_RS01295
uniprot id: A0A1B2HXD4
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1586287:BBK82 RS03980
gene id: 1586287:BBK82_RS03980
uniprot id: A0A1B2HCB6
names: Similarity
messages: Belongs to the TPP enzyme family.

1586287:BBK82 RS15435
gene id: 1586287:BBK82_RS15435
uniprot id: A0A1B2HHR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1586287:BBK82 RS40735
gene id: 1586287:BBK82_RS40735
uniprot id: A0A1B2HUE0
names: Similarity
messages: Belongs to the IlvD/Edd family.

1586287:BBK82 RS03830
gene id: 1586287:BBK82_RS03830
uniprot id: A0A1B2HC93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1586287:BBK82 RS45230
gene id: 1586287:BBK82_RS45230
uniprot id: A0A1B2HWJ9
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

1586287:BBK82 RS20815
gene id: 1586287:BBK82_RS20815
uniprot id: A0A1B2HK82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1586287:BBK82 RS24070
gene id: 1586287:BBK82_RS24070
uniprot id: A0A1B2HLS9
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS43920
gene id: 1586287:BBK82_RS43920
uniprot id: A0A1B2HVX4
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS08985
gene id: 1586287:BBK82_RS08985
uniprot id: A0A1B2HEN4
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS22705
gene id: 1586287:BBK82_RS22705
uniprot id: A0A1B2HL75
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1586287:BBK82 RS14980
gene id: 1586287:BBK82_RS14980
uniprot id: A0A1B2HHI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS22465
gene id: 1586287:BBK82_RS22465
uniprot id: A0A1B2HL09
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1586287:BBK82 RS41535
gene id: 1586287:BBK82_RS41535
uniprot id: A0A1B2HUW8
names: Similarity
messages: Belongs to the CdaR family.

1586287:BBK82 RS26150
gene id: 1586287:BBK82_RS26150
uniprot id: A0A1B2HMV6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1586287:BBK82 RS09810
gene id: 1586287:BBK82_RS09810
uniprot id: A0A1B2HF14
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1586287:BBK82 RS11940
gene id: 1586287:BBK82_RS11940
uniprot id: A0A1B2HG30
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1586287:BBK82 RS30355
gene id: 1586287:BBK82_RS30355
uniprot id: A0A1B2HPR7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1586287:BBK82 RS17125
gene id: 1586287:BBK82_RS17125
uniprot id: A0A1B2HIH1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1586287:BBK82 RS27690
gene id: 1586287:BBK82_RS27690
uniprot id: A0A1B2HNI7
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1586287:BBK82 RS00260
gene id: 1586287:BBK82_RS00260
uniprot id: A0A1B2HAK6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1586287:BBK82 RS17140
gene id: 1586287:BBK82_RS17140
uniprot id: A0A1B2HII4
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1586287:BBK82 RS04900
gene id: 1586287:BBK82_RS04900
uniprot id: A0A1B2HCS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS21950
gene id: 1586287:BBK82_RS21950
uniprot id: A0A1B2HKV3
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1586287:BBK82 RS06600
gene id: 1586287:BBK82_RS06600
uniprot id: A0A1B2HDM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1586287:BBK82 RS45600
gene id: 1586287:BBK82_RS45600
uniprot id: A0A1B2HWM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS09870
gene id: 1586287:BBK82_RS09870
uniprot id: A0A1B2HF22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1586287:BBK82 RS00930
gene id: 1586287:BBK82_RS00930
uniprot id: A0A1B2HAW3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1586287:BBK82 RS41895
gene id: 1586287:BBK82_RS41895
uniprot id: A0A1B2HUW5
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1586287:BBK82 RS12885
gene id: 1586287:BBK82_RS12885
uniprot id: A0A1B2HGJ3
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS13685
gene id: 1586287:BBK82_RS13685
uniprot id: A0A1B2HGW8
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS22610
gene id: 1586287:BBK82_RS22610
uniprot id: A0A1B2HL46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1586287:BBK82 RS12095
gene id: 1586287:BBK82_RS12095
uniprot id: A0A1B2HG62
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS11850
gene id: 1586287:BBK82_RS11850
uniprot id: A0A1B2HG10
names: Subcellular Location Annotation
messages: Cytoplasm

1586287:BBK82 RS21715
gene id: 1586287:BBK82_RS21715
uniprot id: A0A1B2HKP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1586287:BBK82 RS33350
gene id: 1586287:BBK82_RS33350
uniprot id: A0A1B2HR57
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1586287:BBK82 RS22130
gene id: 1586287:BBK82_RS22130
uniprot id: A0A1B2HKX3
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1586287:BBK82 RS27140
gene id: 1586287:BBK82_RS27140
uniprot id: A0A1B2HND0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1586287:BBK82 RS31435
gene id: 1586287:BBK82_RS31435
uniprot id: A0A1B2HQ76
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS10525
gene id: 1586287:BBK82_RS10525
uniprot id: A0A1B2HY08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1586287:BBK82 RS27415
gene id: 1586287:BBK82_RS27415
uniprot id: A0A1B2HND1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1586287:BBK82 RS25390
gene id: 1586287:BBK82_RS25390
uniprot id: A0A1B2HMI0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1586287:BBK82 RS21830
gene id: 1586287:BBK82_RS21830
uniprot id: A0A1B2HKU4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1586287:BBK82 RS02025
gene id: 1586287:BBK82_RS02025
uniprot id: A0A1B2HXK4
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS09670
gene id: 1586287:BBK82_RS09670
uniprot id: A0A1B2HEZ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.

1586287:BBK82 RS34435
gene id: 1586287:BBK82_RS34435
uniprot id: A0A1B2HRJ3
names: Similarity
messages: Belongs to the DNA photolyase family.

1586287:BBK82 RS06835
gene id: 1586287:BBK82_RS06835
uniprot id: A0A1B2HDQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS18295
gene id: 1586287:BBK82_RS18295
uniprot id: A0A1B2HJ18
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1586287:BBK82 RS02955
gene id: 1586287:BBK82_RS02955
uniprot id: A0A1B2HBS7
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1586287:BBK82 RS02840
gene id: 1586287:BBK82_RS02840
uniprot id: A0A1B2HBS1
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1586287:BBK82 RS13300
gene id: 1586287:BBK82_RS13300
uniprot id: A0A1B2HGQ9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1586287:BBK82 RS10320
gene id: 1586287:BBK82_RS10320
uniprot id: A0A1B2HF69
names: Similarity
messages: Belongs to the cytochrome P450 family.

1586287:BBK82 RS00870
gene id: 1586287:BBK82_RS00870
uniprot id: A0A1B2HAV4
names: Function
names: Similarity
messages: Belongs to the transposase IS30 family.
messages: Required for the transposition of the insertion element.

1586287:BBK82 RS35980
gene id: 1586287:BBK82_RS35980
uniprot id: A0A1B2HSA0
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS18170
gene id: 1586287:BBK82_RS18170
uniprot id: A0A1B2HJ00
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS25310
gene id: 1586287:BBK82_RS25310
uniprot id: A0A1B2HMG9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS11875
gene id: 1586287:BBK82_RS11875
uniprot id: A0A1B2HG29
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1586287:BBK82 RS18155
gene id: 1586287:BBK82_RS18155
uniprot id: A0A1B2HIZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1586287:BBK82 RS16580
gene id: 1586287:BBK82_RS16580
uniprot id: A0A1B2HI81
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS45305
gene id: 1586287:BBK82_RS45305
uniprot id: A0A1B2HWH0
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

1586287:BBK82 RS22620
gene id: 1586287:BBK82_RS22620
uniprot id: A0A1B2HL43
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1586287:BBK82 RS18780
gene id: 1586287:BBK82_RS18780
uniprot id: A0A1B2HJC9
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1586287:BBK82 RS04665
gene id: 1586287:BBK82_RS04665
uniprot id: A0A1B2HCN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS45105
gene id: 1586287:BBK82_RS45105
uniprot id: A0A1B2HWG8
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

1586287:BBK82 RS38280
gene id: 1586287:BBK82_RS38280
uniprot id: A0A1B2HTB5
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS22075
gene id: 1586287:BBK82_RS22075
uniprot id: A0A1B2HKW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1586287:BBK82 RS28905
gene id: 1586287:BBK82_RS28905
uniprot id: A0A1B2HP52
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS08905
gene id: 1586287:BBK82_RS08905
uniprot id: A0A1B2HEM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1586287:BBK82 RS31795
gene id: 1586287:BBK82_RS31795
uniprot id: A0A1B2HQF2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1586287:BBK82 RS24780
gene id: 1586287:BBK82_RS24780
uniprot id: A0A1B2HM73
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

1586287:BBK82 RS19230
gene id: 1586287:BBK82_RS19230
uniprot id: A0A1B2HJH9
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1586287:BBK82 RS20545
gene id: 1586287:BBK82_RS20545
uniprot id: A0A1B2HYX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1586287:BBK82 RS44885
gene id: 1586287:BBK82_RS44885
uniprot id: A0A1B2HWF1
names: Similarity
messages: Belongs to the YciI family.

1586287:BBK82 RS51750
gene id: 1586287:BBK82_RS51750
uniprot id: A0A1B2HMX9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS08605
gene id: 1586287:BBK82_RS08605
uniprot id: A0A1B2HEG9
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1586287:BBK82 RS14605
gene id: 1586287:BBK82_RS14605
uniprot id: A0A1B2HHA7
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS11295
gene id: 1586287:BBK82_RS11295
uniprot id: A0A1B2HFS4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS01520
gene id: 1586287:BBK82_RS01520
uniprot id: A0A1B2HXI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS44095
gene id: 1586287:BBK82_RS44095
uniprot id: A0A1B2HVW7
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1586287:BBK82 RS44835
gene id: 1586287:BBK82_RS44835
uniprot id: A0A1B2HW92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS26860
gene id: 1586287:BBK82_RS26860
uniprot id: A0A1B2HN84
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1586287:BBK82 RS43345
gene id: 1586287:BBK82_RS43345
uniprot id: A0A1B2HVP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1586287:BBK82 RS25680
gene id: 1586287:BBK82_RS25680
uniprot id: A0A1B2HMK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1586287:BBK82 RS02970
gene id: 1586287:BBK82_RS02970
uniprot id: A0A1B2HXP2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1586287:BBK82 RS02790
gene id: 1586287:BBK82_RS02790
uniprot id: A0A1B2HBQ1
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1586287:BBK82 RS09470
gene id: 1586287:BBK82_RS09470
uniprot id: A0A1B2HEV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1586287:BBK82 RS19115
gene id: 1586287:BBK82_RS19115
uniprot id: A0A1B2HJF2
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1586287:BBK82 RS36925
gene id: 1586287:BBK82_RS36925
uniprot id: A0A1B2HSS7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS34250
gene id: 1586287:BBK82_RS34250
uniprot id: A0A1B2HRL9
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS45225
gene id: 1586287:BBK82_RS45225
uniprot id: A0A1B2HWH5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1586287:BBK82 RS38165
gene id: 1586287:BBK82_RS38165
uniprot id: A0A1B2HT93
names: Subcellular Location Annotation
messages: Secreted

1586287:BBK82 RS43095
gene id: 1586287:BBK82_RS43095
uniprot id: A0A1B2HVI1
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1586287:BBK82 RS04565
gene id: 1586287:BBK82_RS04565
uniprot id: A0A1B2HCL0
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1586287:BBK82 RS26455
gene id: 1586287:BBK82_RS26455
uniprot id: A0A1B2HMZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1586287:BBK82 RS09370
gene id: 1586287:BBK82_RS09370
uniprot id: A0A1B2HEU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS02900
gene id: 1586287:BBK82_RS02900
uniprot id: A0A1B2HBT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1586287:BBK82 RS04100
gene id: 1586287:BBK82_RS04100
uniprot id: A0A1B2HCD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS27420
gene id: 1586287:BBK82_RS27420
uniprot id: A0A1B2HNE6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

1586287:BBK82 RS05455
gene id: 1586287:BBK82_RS05455
uniprot id: A0A1B2HD22
names: Similarity
messages: Belongs to the EspG family.

1586287:BBK82 RS33235
gene id: 1586287:BBK82_RS33235
uniprot id: A0A1B2HR61
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1586287:BBK82 RS16250
gene id: 1586287:BBK82_RS16250
uniprot id: A0A1B2HI40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1586287:BBK82 RS22065
gene id: 1586287:BBK82_RS22065
uniprot id: A0A1B2HKW6
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1586287:BBK82 RS03535
gene id: 1586287:BBK82_RS03535
uniprot id: A0A1B2HC36
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1586287:BBK82 RS20565
gene id: 1586287:BBK82_RS20565
uniprot id: A0A1B2HK40
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS01820
gene id: 1586287:BBK82_RS01820
uniprot id: A0A1B2HBB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1586287:BBK82 RS02670
gene id: 1586287:BBK82_RS02670
uniprot id: A0A1B2HBS4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS04260
gene id: 1586287:BBK82_RS04260
uniprot id: A0A1B2HCF8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1586287:BBK82 RS13295
gene id: 1586287:BBK82_RS13295
uniprot id: A0A1B2HGQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS38020
gene id: 1586287:BBK82_RS38020
uniprot id: A0A1B2HTB2
names: Similarity
messages: Belongs to the CdaR family.

1586287:BBK82 RS24230
gene id: 1586287:BBK82_RS24230
uniprot id: A0A1B2HLY4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1586287:BBK82 RS12700
gene id: 1586287:BBK82_RS12700
uniprot id: A0A1B2HGF4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1586287:BBK82 RS25690
gene id: 1586287:BBK82_RS25690
uniprot id: A0A1B2HMM3
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1586287:BBK82 RS27810
gene id: 1586287:BBK82_RS27810
uniprot id: A0A1B2HNK7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1586287:BBK82 RS21925
gene id: 1586287:BBK82_RS21925
uniprot id: A0A1B2HKS6
names: Subunit
messages: Homotetramer.

1586287:BBK82 RS23545
gene id: 1586287:BBK82_RS23545
uniprot id: A0A1B2HLL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS11330
gene id: 1586287:BBK82_RS11330
uniprot id: A0A1B2HFR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS10185
gene id: 1586287:BBK82_RS10185
uniprot id: A0A1B2HF64
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1586287:BBK82 RS31900
gene id: 1586287:BBK82_RS31900
uniprot id: A0A1B2HQH4
names: Similarity
messages: Belongs to the EspG family.

1586287:BBK82 RS13690
gene id: 1586287:BBK82_RS13690
uniprot id: A0A1B2HGW6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1586287:BBK82 RS04635
gene id: 1586287:BBK82_RS04635
uniprot id: A0A1B2HXQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1586287:BBK82 RS25430
gene id: 1586287:BBK82_RS25430
uniprot id: A0A1B2HMI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1586287:BBK82 RS23775
gene id: 1586287:BBK82_RS23775
uniprot id: A0A1B2HLQ6
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1586287:BBK82 RS16650
gene id: 1586287:BBK82_RS16650
uniprot id: A0A1B2HI90
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1586287:BBK82 RS03775
gene id: 1586287:BBK82_RS03775
uniprot id: A0A1B2HC84
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1586287:BBK82 RS18825
gene id: 1586287:BBK82_RS18825
uniprot id: A0A1B2HJB9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS20060
gene id: 1586287:BBK82_RS20060
uniprot id: A0A1B2HJX3
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1586287:BBK82 RS25395
gene id: 1586287:BBK82_RS25395
uniprot id: A0A1B2HMI4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1586287:BBK82 RS24165
gene id: 1586287:BBK82_RS24165
uniprot id: A0A1B2HLX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1586287:BBK82 RS39565
gene id: 1586287:BBK82_RS39565
uniprot id: A0A1B2HU11
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS23940
gene id: 1586287:BBK82_RS23940
uniprot id: A0A1B2HLQ9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS13410
gene id: 1586287:BBK82_RS13410
uniprot id: A0A1B2HGT7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1586287:BBK82 RS04505
gene id: 1586287:BBK82_RS04505
uniprot id: A0A1B2HCL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1586287:BBK82 RS33400
gene id: 1586287:BBK82_RS33400
uniprot id: A0A1B2HR89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1586287:BBK82 RS39735
gene id: 1586287:BBK82_RS39735
uniprot id: A0A1B2HU13
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS20450
gene id: 1586287:BBK82_RS20450
uniprot id: A0A1B2HK26
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS30720
gene id: 1586287:BBK82_RS30720
uniprot id: A0A1B2HPV5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1586287:BBK82 RS17160
gene id: 1586287:BBK82_RS17160
uniprot id: A0A1B2HIH2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1586287:BBK82 RS04880
gene id: 1586287:BBK82_RS04880
uniprot id: A0A1B2HCR7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1586287:BBK82 RS21115
gene id: 1586287:BBK82_RS21115
uniprot id: A0A1B2HKH8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1586287:BBK82 RS20850
gene id: 1586287:BBK82_RS20850
uniprot id: A0A1B2HK94
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

1586287:BBK82 RS02320
gene id: 1586287:BBK82_RS02320
uniprot id: A0A1B2HBL4
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1586287:BBK82 RS41955
gene id: 1586287:BBK82_RS41955
uniprot id: A0A1B2HUY1
names: Similarity
messages: Belongs to the cytochrome P450 family.

1586287:BBK82 RS06310
gene id: 1586287:BBK82_RS06310
uniprot id: A0A1B2HDF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS40620
gene id: 1586287:BBK82_RS40620
uniprot id: A0A1B2I0F7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS35750
gene id: 1586287:BBK82_RS35750
uniprot id: A0A1B2HSA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS31610
gene id: 1586287:BBK82_RS31610
uniprot id: A0A1B2HQC7
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1586287:BBK82 RS11625
gene id: 1586287:BBK82_RS11625
uniprot id: A0A1B2HFV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1586287:BBK82 RS46100
gene id: 1586287:BBK82_RS46100
uniprot id: A0A1B2HWV3
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1586287:BBK82 RS23710
gene id: 1586287:BBK82_RS23710
uniprot id: A0A1B2HLM3
names: Similarity
messages: Belongs to the peptidase S14 family.

1586287:BBK82 RS20035
gene id: 1586287:BBK82_RS20035
uniprot id: A0A1B2HJU3
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1586287:BBK82 RS17475
gene id: 1586287:BBK82_RS17475
uniprot id: A0A1B2HIQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1586287:BBK82 RS41795
gene id: 1586287:BBK82_RS41795
uniprot id: A0A1B2HUV1
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS23080
gene id: 1586287:BBK82_RS23080
uniprot id: A0A1B2HLB3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1586287:BBK82 RS18710
gene id: 1586287:BBK82_RS18710
uniprot id: A0A1B2HJA2
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1586287:BBK82 RS14520
gene id: 1586287:BBK82_RS14520
uniprot id: A0A1B2HH90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1586287:BBK82 RS31785
gene id: 1586287:BBK82_RS31785
uniprot id: A0A1B2HZQ2
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS45960
gene id: 1586287:BBK82_RS45960
uniprot id: A0A1B2HWT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1586287:BBK82 RS15750
gene id: 1586287:BBK82_RS15750
uniprot id: A0A1B2HHW7
names: Similarity
messages: Belongs to the GARS family.

1586287:BBK82 RS44320
gene id: 1586287:BBK82_RS44320
uniprot id: A0A1B2HW21
names: Similarity
messages: Belongs to the cytochrome P450 family.

1586287:BBK82 RS18010
gene id: 1586287:BBK82_RS18010
uniprot id: A0A1B2HIX6
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1586287:BBK82 RS01015
gene id: 1586287:BBK82_RS01015
uniprot id: A0A1B2HAX8
names: Similarity
messages: Belongs to the peptidase S8 family.

1586287:BBK82 RS06080
gene id: 1586287:BBK82_RS06080
uniprot id: A0A1B2HDC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1586287:BBK82 RS22810
gene id: 1586287:BBK82_RS22810
uniprot id: A0A1B2HL69
names: Similarity
messages: Belongs to the FPG family.

1586287:BBK82 RS10025
gene id: 1586287:BBK82_RS10025
uniprot id: A0A1B2HF78
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

1586287:BBK82 RS11300
gene id: 1586287:BBK82_RS11300
uniprot id: A0A1B2HFR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1586287:BBK82 RS24410
gene id: 1586287:BBK82_RS24410
uniprot id: A0A1B2HLY9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1586287:BBK82 RS45965
gene id: 1586287:BBK82_RS45965
uniprot id: A0A1B2HWW6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

1586287:BBK82 RS43645
gene id: 1586287:BBK82_RS43645
uniprot id: A0A1B2HVU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

1586287:BBK82 RS01360
gene id: 1586287:BBK82_RS01360
uniprot id: A0A1B2HB21
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1586287:BBK82 RS09875
gene id: 1586287:BBK82_RS09875
uniprot id: A0A1B2HF21
names: Similarity
messages: Belongs to the FBPase class 2 family.

1586287:BBK82 RS31280
gene id: 1586287:BBK82_RS31280
uniprot id: A0A1B2HQ74
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1586287:BBK82 RS11630
gene id: 1586287:BBK82_RS11630
uniprot id: A0A1B2HFY9
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1586287:BBK82 RS46980
gene id: 1586287:BBK82_RS46980
uniprot id: A0A1B2HXD2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1586287:BBK82 RS04760
gene id: 1586287:BBK82_RS04760
uniprot id: A0A1B2HCQ9
names: Similarity
messages: Belongs to the ComB family.

1586287:BBK82 RS31015
gene id: 1586287:BBK82_RS31015
uniprot id: A0A1B2HQ24
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1586287:BBK82 RS31115
gene id: 1586287:BBK82_RS31115
uniprot id: A0A1B2HQ26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS15865
gene id: 1586287:BBK82_RS15865
uniprot id: A0A1B2HHY8
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1586287:BBK82 RS06305
gene id: 1586287:BBK82_RS06305
uniprot id: A0A1B2HDE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS45895
gene id: 1586287:BBK82_RS45895
uniprot id: A0A1B2HWX8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1586287:BBK82 RS43485
gene id: 1586287:BBK82_RS43485
uniprot id: A0A1B2HVR2
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

1586287:BBK82 RS27695
gene id: 1586287:BBK82_RS27695
uniprot id: A0A1B2HNK4
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1586287:BBK82 RS12565
gene id: 1586287:BBK82_RS12565
uniprot id: A0A1B2HGC4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1586287:BBK82 RS22300
gene id: 1586287:BBK82_RS22300
uniprot id: A0A1B2HYX9
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1586287:BBK82 RS25695
gene id: 1586287:BBK82_RS25695
uniprot id: A0A1B2HMJ9
names: Similarity
messages: Belongs to the peptidase S26 family.

1586287:BBK82 RS38120
gene id: 1586287:BBK82_RS38120
uniprot id: A0A1B2HTB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS07125
gene id: 1586287:BBK82_RS07125
uniprot id: A0A1B2HDT4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1586287:BBK82 RS28540
gene id: 1586287:BBK82_RS28540
uniprot id: A0A1B2HNW7
names: Similarity
messages: Belongs to the universal stress protein A family.

1586287:BBK82 RS32855
gene id: 1586287:BBK82_RS32855
uniprot id: A0A1B2HQX6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1586287:BBK82 RS17180
gene id: 1586287:BBK82_RS17180
uniprot id: A0A1B2HIJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1586287:BBK82 RS14820
gene id: 1586287:BBK82_RS14820
uniprot id: A0A1B2HHF8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1586287:BBK82 RS45170
gene id: 1586287:BBK82_RS45170
uniprot id: A0A1B2HWG4
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

1586287:BBK82 RS38885
gene id: 1586287:BBK82_RS38885
uniprot id: A0A1B2HTK4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1586287:BBK82 RS13915
gene id: 1586287:BBK82_RS13915
uniprot id: A0A1B2HH07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1586287:BBK82 RS06680
gene id: 1586287:BBK82_RS06680
uniprot id: A0A1B2HDP5
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS02780
gene id: 1586287:BBK82_RS02780
uniprot id: A0A1B2HBR3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1586287:BBK82 RS43685
gene id: 1586287:BBK82_RS43685
uniprot id: A0A1B2HVR4
names: Similarity
messages: Belongs to the fabD family.

1586287:BBK82 RS04120
gene id: 1586287:BBK82_RS04120
uniprot id: A0A1B2HCF4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1586287:BBK82 RS40555
gene id: 1586287:BBK82_RS40555
uniprot id: A0A1B2HUB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1586287:BBK82 RS15410
gene id: 1586287:BBK82_RS15410
uniprot id: A0A1B2HHN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS15105
gene id: 1586287:BBK82_RS15105
uniprot id: A0A1B2HHK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1586287:BBK82 RS41660
gene id: 1586287:BBK82_RS41660
uniprot id: A0A1B2HUV2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1586287:BBK82 RS14835
gene id: 1586287:BBK82_RS14835
uniprot id: A0A1B2HHF9
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS39365
gene id: 1586287:BBK82_RS39365
uniprot id: A0A1B2HTY3
names: Similarity
messages: Belongs to the aldose epimerase family.

1586287:BBK82 RS02455
gene id: 1586287:BBK82_RS02455
uniprot id: A0A1B2HBJ4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1586287:BBK82 RS17275
gene id: 1586287:BBK82_RS17275
uniprot id: A0A1B2HIM0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS00015
gene id: 1586287:BBK82_RS00015
uniprot id: A0A1B2HAG6
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS45775
gene id: 1586287:BBK82_RS45775
uniprot id: A0A1B2HWV7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1586287:BBK82 RS22010
gene id: 1586287:BBK82_RS22010
uniprot id: A0A1B2HKV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1586287:BBK82 RS45770
gene id: 1586287:BBK82_RS45770
uniprot id: A0A1B2HWR3
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1586287:BBK82 RS36860
gene id: 1586287:BBK82_RS36860
uniprot id: A0A1B2HSR1
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS22135
gene id: 1586287:BBK82_RS22135
uniprot id: A0A1B2HKX4
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

1586287:BBK82 RS40570
gene id: 1586287:BBK82_RS40570
uniprot id: A0A1B2HUB5
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS27635
gene id: 1586287:BBK82_RS27635
uniprot id: A0A1B2HNI3
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS06895
gene id: 1586287:BBK82_RS06895
uniprot id: A0A1B2HDP1
names: Similarity
messages: Belongs to the asparagine synthetase family.

1586287:BBK82 RS19555
gene id: 1586287:BBK82_RS19555
uniprot id: A0A1B2HJN7
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

1586287:BBK82 RS22150
gene id: 1586287:BBK82_RS22150
uniprot id: A0A1B2HKW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1586287:BBK82 RS45815
gene id: 1586287:BBK82_RS45815
uniprot id: A0A1B2HWR1
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

1586287:BBK82 RS46185
gene id: 1586287:BBK82_RS46185
uniprot id: A0A1B2HWY5
names: Similarity
messages: Belongs to the glutamine synthetase family.

1586287:BBK82 RS42495
gene id: 1586287:BBK82_RS42495
uniprot id: A0A1B2HVD1
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1586287:BBK82 RS39430
gene id: 1586287:BBK82_RS39430
uniprot id: A0A1B2HTV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the faeC family.
messages: Involved in degradation of plant cell walls. Hydrolyzes the feruloyl-arabinose ester bond in arabinoxylans, and the feruloyl-galactose ester bond in pectin. Active against paranitrophenyl-acetate, methyl ferulate and wheat arabinoxylan.
messages: Secreted

1586287:BBK82 RS43100
gene id: 1586287:BBK82_RS43100
uniprot id: A0A1B2HVM8
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1586287:BBK82 RS21470
gene id: 1586287:BBK82_RS21470
uniprot id: A0A1B2HKL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1586287:BBK82 RS08525
gene id: 1586287:BBK82_RS08525
uniprot id: A0A1B2HEG1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1586287:BBK82 RS19390
gene id: 1586287:BBK82_RS19390
uniprot id: A0A1B2HJI9
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1586287:BBK82 RS27510
gene id: 1586287:BBK82_RS27510
uniprot id: A0A1B2HNF9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1586287:BBK82 RS01940
gene id: 1586287:BBK82_RS01940
uniprot id: A0A1B2HBC2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

1586287:BBK82 RS36755
gene id: 1586287:BBK82_RS36755
uniprot id: A0A1B2HSN9
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1586287:BBK82 RS13680
gene id: 1586287:BBK82_RS13680
uniprot id: A0A1B2HYD5
names: Similarity
names: Subunit
messages: Belongs to the Bpa family.
messages: Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings.

1586287:BBK82 RS18355
gene id: 1586287:BBK82_RS18355
uniprot id: A0A1B2HJ31
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1586287:BBK82 RS01645
gene id: 1586287:BBK82_RS01645
uniprot id: A0A1B2HB69
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

1586287:BBK82 RS22960
gene id: 1586287:BBK82_RS22960
uniprot id: A0A1B2HLB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS41655
gene id: 1586287:BBK82_RS41655
uniprot id: A0A1B2HUT1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1586287:BBK82 RS00960
gene id: 1586287:BBK82_RS00960
uniprot id: A0A1B2HAW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1586287:BBK82 RS04445
gene id: 1586287:BBK82_RS04445
uniprot id: A0A1B2HCH9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1586287:BBK82 RS12065
gene id: 1586287:BBK82_RS12065
uniprot id: A0A1B2HG40
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1586287:BBK82 RS25330
gene id: 1586287:BBK82_RS25330
uniprot id: A0A1B2HMH0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1586287:BBK82 RS22770
gene id: 1586287:BBK82_RS22770
uniprot id: A0A1B2HL83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1586287:BBK82 RS17620
gene id: 1586287:BBK82_RS17620
uniprot id: A0A1B2HIN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1586287:BBK82 RS06135
gene id: 1586287:BBK82_RS06135
uniprot id: A0A1B2HDD3
names: Similarity
messages: Belongs to the AHA1 family.

1586287:BBK82 RS29965
gene id: 1586287:BBK82_RS29965
uniprot id: A0A1B2HPH3
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS17570
gene id: 1586287:BBK82_RS17570
uniprot id: A0A1B2HIN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1586287:BBK82 RS14925
gene id: 1586287:BBK82_RS14925
uniprot id: A0A1B2HHH6
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS13305
gene id: 1586287:BBK82_RS13305
uniprot id: A0A1B2HGT4
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1586287:BBK82 RS02625
gene id: 1586287:BBK82_RS02625
uniprot id: A0A1B2HBM6
names: Similarity
messages: Belongs to the AHA1 family.

1586287:BBK82 RS39975
gene id: 1586287:BBK82_RS39975
uniprot id: A0A1B2HU22
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1586287:BBK82 RS33585
gene id: 1586287:BBK82_RS33585
uniprot id: A0A1B2HR97
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1586287:BBK82 RS36155
gene id: 1586287:BBK82_RS36155
uniprot id: A0A1B2I022
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1586287:BBK82 RS02770
gene id: 1586287:BBK82_RS02770
uniprot id: A0A1B2HBS2
names: Similarity
messages: Belongs to the CdaR family.

1586287:BBK82 RS00055
gene id: 1586287:BBK82_RS00055
uniprot id: A0A1B2HAG5
names: Similarity
messages: Belongs to the HSP15 family.

1586287:BBK82 RS27160
gene id: 1586287:BBK82_RS27160
uniprot id: A0A1B2HN99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1586287:BBK82 RS14900
gene id: 1586287:BBK82_RS14900
uniprot id: A0A1B2HHG5
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1586287:BBK82 RS20595
gene id: 1586287:BBK82_RS20595
uniprot id: A0A1B2HYW1
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1586287:BBK82 RS44400
gene id: 1586287:BBK82_RS44400
uniprot id: A0A1B2HW50
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

1586287:BBK82 RS20130
gene id: 1586287:BBK82_RS20130
uniprot id: A0A1B2HK02
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1586287:BBK82 RS37450
gene id: 1586287:BBK82_RS37450
uniprot id: A0A1B2HT04
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1586287:BBK82 RS45245
gene id: 1586287:BBK82_RS45245
uniprot id: A0A1B2HWH2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1586287:BBK82 RS37285
gene id: 1586287:BBK82_RS37285
uniprot id: A0A1B2HSV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS18265
gene id: 1586287:BBK82_RS18265
uniprot id: A0A1B2HJ22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1586287:BBK82 RS18905
gene id: 1586287:BBK82_RS18905
uniprot id: A0A1B2HJC6
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS43425
gene id: 1586287:BBK82_RS43425
uniprot id: A0A1B2HVQ2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1586287:BBK82 RS12615
gene id: 1586287:BBK82_RS12615
uniprot id: A0A1B2HGD3
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS17690
gene id: 1586287:BBK82_RS17690
uniprot id: A0A1B2HIR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1586287:BBK82 RS14025
gene id: 1586287:BBK82_RS14025
uniprot id: A0A1B2HH28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

1586287:BBK82 RS19240
gene id: 1586287:BBK82_RS19240
uniprot id: A0A1B2HJH6
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS23000
gene id: 1586287:BBK82_RS23000
uniprot id: A0A1B2HLB7
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1586287:BBK82 RS27400
gene id: 1586287:BBK82_RS27400
uniprot id: A0A1B2HZC7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1586287:BBK82 RS09725
gene id: 1586287:BBK82_RS09725
uniprot id: A0A1B2HF03
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1586287:BBK82 RS27785
gene id: 1586287:BBK82_RS27785
uniprot id: A0A1B2HNK0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS15490
gene id: 1586287:BBK82_RS15490
uniprot id: A0A1B2HHS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1586287:BBK82 RS15120
gene id: 1586287:BBK82_RS15120
uniprot id: A0A1B2HHK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1586287:BBK82 RS17175
gene id: 1586287:BBK82_RS17175
uniprot id: A0A1B2HII9
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS12160
gene id: 1586287:BBK82_RS12160
uniprot id: A0A1B2HG72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS23890
gene id: 1586287:BBK82_RS23890
uniprot id: A0A1B2HLS8
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS13380
gene id: 1586287:BBK82_RS13380
uniprot id: A0A1B2HGR5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1586287:BBK82 RS35480
gene id: 1586287:BBK82_RS35480
uniprot id: A0A1B2HS39
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

1586287:BBK82 RS23370
gene id: 1586287:BBK82_RS23370
uniprot id: A0A1B2HYZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1586287:BBK82 RS12820
gene id: 1586287:BBK82_RS12820
uniprot id: A0A1B2HGH9
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

1586287:BBK82 RS30220
gene id: 1586287:BBK82_RS30220
uniprot id: A0A1B2HPS0
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1586287:BBK82 RS21070
gene id: 1586287:BBK82_RS21070
uniprot id: A0A1B2HKD4
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

1586287:BBK82 RS08685
gene id: 1586287:BBK82_RS08685
uniprot id: A0A1B2HEI3
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS22315
gene id: 1586287:BBK82_RS22315
uniprot id: A0A1B2HKZ1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS20740
gene id: 1586287:BBK82_RS20740
uniprot id: A0A1B2HK77
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS11485
gene id: 1586287:BBK82_RS11485
uniprot id: A0A1B2HFV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1586287:BBK82 RS12055
gene id: 1586287:BBK82_RS12055
uniprot id: A0A1B2HG51
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1586287:BBK82 RS36340
gene id: 1586287:BBK82_RS36340
uniprot id: A0A1B2HSE0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1586287:BBK82 RS24135
gene id: 1586287:BBK82_RS24135
uniprot id: A0A1B2HLW7
names: Similarity
messages: Belongs to the peptidase S9C family.

1586287:BBK82 RS16295
gene id: 1586287:BBK82_RS16295
uniprot id: A0A1B2HI53
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS19880
gene id: 1586287:BBK82_RS19880
uniprot id: A0A1B2HJW9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1586287:BBK82 RS04440
gene id: 1586287:BBK82_RS04440
uniprot id: A0A1B2HCM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1586287:BBK82 RS12735
gene id: 1586287:BBK82_RS12735
uniprot id: A0A1B2HGG9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

1586287:BBK82 RS38930
gene id: 1586287:BBK82_RS38930
uniprot id: A0A1B2HTM2
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

1586287:BBK82 RS02280
gene id: 1586287:BBK82_RS02280
uniprot id: A0A1B2HBG7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS12980
gene id: 1586287:BBK82_RS12980
uniprot id: A0A1B2HGM1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1586287:BBK82 RS43180
gene id: 1586287:BBK82_RS43180
uniprot id: A0A1B2HVN3
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

1586287:BBK82 RS22795
gene id: 1586287:BBK82_RS22795
uniprot id: A0A1B2HL72
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS18995
gene id: 1586287:BBK82_RS18995
uniprot id: A0A1B2HJE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1586287:BBK82 RS41815
gene id: 1586287:BBK82_RS41815
uniprot id: A0A1B2HUV6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1586287:BBK82 RS39155
gene id: 1586287:BBK82_RS39155
uniprot id: A0A1B2HTS4
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS01490
gene id: 1586287:BBK82_RS01490
uniprot id: A0A1B2HXJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1586287:BBK82 RS40345
gene id: 1586287:BBK82_RS40345
uniprot id: A0A1B2HUB0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1586287:BBK82 RS40255
gene id: 1586287:BBK82_RS40255
uniprot id: A0A1B2HU74
names: Similarity
messages: Belongs to the peptidase S8 family.

1586287:BBK82 RS16900
gene id: 1586287:BBK82_RS16900
uniprot id: A0A1B2HYI0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1586287:BBK82 RS39950
gene id: 1586287:BBK82_RS39950
uniprot id: A0A1B2HU28
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1586287:BBK82 RS23460
gene id: 1586287:BBK82_RS23460
uniprot id: A0A1B2HLI0
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1586287:BBK82 RS43015
gene id: 1586287:BBK82_RS43015
uniprot id: A0A1B2I0M6
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS15660
gene id: 1586287:BBK82_RS15660
uniprot id: A0A1B2HHS6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1586287:BBK82 RS17130
gene id: 1586287:BBK82_RS17130
uniprot id: A0A1B2HIH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1586287:BBK82 RS39880
gene id: 1586287:BBK82_RS39880
uniprot id: A0A1B2HU18
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

1586287:BBK82 RS10845
gene id: 1586287:BBK82_RS10845
uniprot id: A0A1B2HFL3
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1586287:BBK82 RS12855
gene id: 1586287:BBK82_RS12855
uniprot id: A0A1B2HGH7
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS04835
gene id: 1586287:BBK82_RS04835
uniprot id: A0A1B2HXP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1586287:BBK82 RS16080
gene id: 1586287:BBK82_RS16080
uniprot id: A0A1B2HI17
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS11200
gene id: 1586287:BBK82_RS11200
uniprot id: A0A1B2HFR4
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1586287:BBK82 RS35275
gene id: 1586287:BBK82_RS35275
uniprot id: A0A1B2HRW1
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS00815
gene id: 1586287:BBK82_RS00815
uniprot id: A0A1B2HAU2
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1586287:BBK82 RS22090
gene id: 1586287:BBK82_RS22090
uniprot id: A0A1B2HKV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1586287:BBK82 RS43065
gene id: 1586287:BBK82_RS43065
uniprot id: A0A1B2HVK1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS32830
gene id: 1586287:BBK82_RS32830
uniprot id: A0A1B2HQZ9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1586287:BBK82 RS46140
gene id: 1586287:BBK82_RS46140
uniprot id: A0A1B2HWW2
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS23905
gene id: 1586287:BBK82_RS23905
uniprot id: A0A1B2HLP8
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

1586287:BBK82 RS08180
gene id: 1586287:BBK82_RS08180
uniprot id: A0A1B2HEA8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS09620
gene id: 1586287:BBK82_RS09620
uniprot id: A0A1B2HEY9
names: Similarity
messages: Belongs to the LOG family.

1586287:BBK82 RS03900
gene id: 1586287:BBK82_RS03900
uniprot id: A0A1B2HC97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1586287:BBK82 RS28700
gene id: 1586287:BBK82_RS28700
uniprot id: A0A1B2HNZ6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS22085
gene id: 1586287:BBK82_RS22085
uniprot id: A0A1B2HKW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1586287:BBK82 RS23285
gene id: 1586287:BBK82_RS23285
uniprot id: A0A1B2HLE8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1586287:BBK82 RS24450
gene id: 1586287:BBK82_RS24450
uniprot id: A0A1B2HLZ2
names: Similarity
messages: Belongs to the glycosyl hydrolase.

1586287:BBK82 RS02720
gene id: 1586287:BBK82_RS02720
uniprot id: A0A1B2HBP9
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1586287:BBK82 RS24510
gene id: 1586287:BBK82_RS24510
uniprot id: A0A1B2HM21
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1586287:BBK82 RS02290
gene id: 1586287:BBK82_RS02290
uniprot id: A0A1B2HBI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

1586287:BBK82 RS17580
gene id: 1586287:BBK82_RS17580
uniprot id: A0A1B2HIQ0
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1586287:BBK82 RS25735
gene id: 1586287:BBK82_RS25735
uniprot id: A0A1B2HMN1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1586287:BBK82 RS06160
gene id: 1586287:BBK82_RS06160
uniprot id: A0A1B2HDC9
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1586287:BBK82 RS00790
gene id: 1586287:BBK82_RS00790
uniprot id: A0A1B2HAT1
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1586287:BBK82 RS26390
gene id: 1586287:BBK82_RS26390
uniprot id: A0A1B2HZ99
names: Similarity
messages: Belongs to the IucA/IucC family.

1586287:BBK82 RS36825
gene id: 1586287:BBK82_RS36825
uniprot id: A0A1B2HSS4
names: Similarity
messages: Belongs to the peptidase S33 family.

1586287:BBK82 RS36540
gene id: 1586287:BBK82_RS36540
uniprot id: A0A1B2HSK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1586287:BBK82 RS51570
gene id: 1586287:BBK82_RS51570
uniprot id: A0A1B2HH49
names: Similarity
messages: Belongs to the cytochrome P450 family.

1586287:BBK82 RS19100
gene id: 1586287:BBK82_RS19100
uniprot id: A0A1B2HJF1
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1586287:BBK82 RS10975
gene id: 1586287:BBK82_RS10975
uniprot id: A0A1B2HFM4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1586287:BBK82 RS06770
gene id: 1586287:BBK82_RS06770
uniprot id: A0A1B2HDM8
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS26285
gene id: 1586287:BBK82_RS26285
uniprot id: A0A1B2HMX8
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1586287:BBK82 RS14290
gene id: 1586287:BBK82_RS14290
uniprot id: A0A1B2HYE8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1586287:BBK82 RS21530
gene id: 1586287:BBK82_RS21530
uniprot id: A0A1B2HKL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1586287:BBK82 RS35320
gene id: 1586287:BBK82_RS35320
uniprot id: A0A1B2HS04
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1586287:BBK82 RS20645
gene id: 1586287:BBK82_RS20645
uniprot id: A0A1B2HK86
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS16620
gene id: 1586287:BBK82_RS16620
uniprot id: A0A1B2HI86
names: Similarity
messages: Belongs to the peptidase C56 family.

1586287:BBK82 RS51755
gene id: 1586287:BBK82_RS51755
uniprot id: A0A1B2HMZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1586287:BBK82 RS30575
gene id: 1586287:BBK82_RS30575
uniprot id: A0A1B2HPV8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1586287:BBK82 RS38680
gene id: 1586287:BBK82_RS38680
uniprot id: A0A1B2I074
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS04785
gene id: 1586287:BBK82_RS04785
uniprot id: A0A1B2HCN4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1586287:BBK82 RS21450
gene id: 1586287:BBK82_RS21450
uniprot id: A0A1B2HYY5
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1586287:BBK82 RS25580
gene id: 1586287:BBK82_RS25580
uniprot id: A0A1B2HMJ2
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS11945
gene id: 1586287:BBK82_RS11945
uniprot id: A0A1B2HG12
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

1586287:BBK82 RS14855
gene id: 1586287:BBK82_RS14855
uniprot id: A0A1B2HYE4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1586287:BBK82 RS10990
gene id: 1586287:BBK82_RS10990
uniprot id: A0A1B2HFM1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1586287:BBK82 RS34060
gene id: 1586287:BBK82_RS34060
uniprot id: A0A1B2HRE8
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

1586287:BBK82 RS42435
gene id: 1586287:BBK82_RS42435
uniprot id: A0A1B2HV55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

1586287:BBK82 RS41600
gene id: 1586287:BBK82_RS41600
uniprot id: A0A1B2HUW6
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

1586287:BBK82 RS19450
gene id: 1586287:BBK82_RS19450
uniprot id: A0A1B2HJN6
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1586287:BBK82 RS04405
gene id: 1586287:BBK82_RS04405
uniprot id: A0A1B2HXN5
names: Similarity
messages: Belongs to the cytochrome P450 family.

1586287:BBK82 RS27830
gene id: 1586287:BBK82_RS27830
uniprot id: A0A1B2HNJ4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1586287:BBK82 RS33185
gene id: 1586287:BBK82_RS33185
uniprot id: A0A1B2HR29
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS08760
gene id: 1586287:BBK82_RS08760
uniprot id: A0A1B2HEJ3
names: Similarity
messages: Belongs to the peptidase C40 family.

1586287:BBK82 RS12470
gene id: 1586287:BBK82_RS12470
uniprot id: A0A1B2HGB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1586287:BBK82 RS38935
gene id: 1586287:BBK82_RS38935
uniprot id: A0A1B2HTR2
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

1586287:BBK82 RS08420
gene id: 1586287:BBK82_RS08420
uniprot id: A0A1B2HEE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1586287:BBK82 RS26870
gene id: 1586287:BBK82_RS26870
uniprot id: A0A1B2HN48
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1586287:BBK82 RS39285
gene id: 1586287:BBK82_RS39285
uniprot id: A0A1B2HTU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS27720
gene id: 1586287:BBK82_RS27720
uniprot id: A0A1B2HNI4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1586287:BBK82 RS39055
gene id: 1586287:BBK82_RS39055
uniprot id: A0A1B2HTN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS01720
gene id: 1586287:BBK82_RS01720
uniprot id: A0A1B2HB83
names: Similarity
messages: Belongs to the AHA1 family.

1586287:BBK82 RS24075
gene id: 1586287:BBK82_RS24075
uniprot id: A0A1B2HLS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the UPF0157 (GrpB) family.
messages: In the N-terminal section; belongs to the CoaE family.

1586287:BBK82 RS09060
gene id: 1586287:BBK82_RS09060
uniprot id: A0A1B2HXX5
names: Similarity
messages: Belongs to the cytochrome P450 family.

1586287:BBK82 RS18475
gene id: 1586287:BBK82_RS18475
uniprot id: A0A1B2HJ41
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS08430
gene id: 1586287:BBK82_RS08430
uniprot id: A0A1B2HEF1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1586287:BBK82 RS28460
gene id: 1586287:BBK82_RS28460
uniprot id: A0A1B2HNU3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1586287:BBK82 RS26155
gene id: 1586287:BBK82_RS26155
uniprot id: A0A1B2HMV7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1586287:BBK82 RS23925
gene id: 1586287:BBK82_RS23925
uniprot id: A0A1B2HLS3
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS43755
gene id: 1586287:BBK82_RS43755
uniprot id: A0A1B2HVQ7
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

1586287:BBK82 RS04510
gene id: 1586287:BBK82_RS04510
uniprot id: A0A1B2HCJ9
names: Similarity
messages: Belongs to the peptidase S8 family.

1586287:BBK82 RS32380
gene id: 1586287:BBK82_RS32380
uniprot id: A0A1B2HZR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.
messages: Cytoplasm
messages: Homodimer.

1586287:BBK82 RS00120
gene id: 1586287:BBK82_RS00120
uniprot id: A0A1B2HX99
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1586287:BBK82 RS19040
gene id: 1586287:BBK82_RS19040
uniprot id: A0A1B2HJF9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS01780
gene id: 1586287:BBK82_RS01780
uniprot id: A0A1B2HBA6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1586287:BBK82 RS36260
gene id: 1586287:BBK82_RS36260
uniprot id: A0A1B2HSE2
names: Similarity
messages: Belongs to the YciI family.

1586287:BBK82 RS21415
gene id: 1586287:BBK82_RS21415
uniprot id: A0A1B2HKJ3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS07170
gene id: 1586287:BBK82_RS07170
uniprot id: A0A1B2HDX1
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1586287:BBK82 RS41220
gene id: 1586287:BBK82_RS41220
uniprot id: A0A1B2HUM7
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS40310
gene id: 1586287:BBK82_RS40310
uniprot id: A0A1B2HU78
names: Similarity
messages: Belongs to the neutral ceramidase family.

1586287:BBK82 RS16930
gene id: 1586287:BBK82_RS16930
uniprot id: A0A1B2HID3
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS31545
gene id: 1586287:BBK82_RS31545
uniprot id: A0A1B2HQD0
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

1586287:BBK82 RS33930
gene id: 1586287:BBK82_RS33930
uniprot id: A0A1B2HRD2
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS03805
gene id: 1586287:BBK82_RS03805
uniprot id: A0A1B2HCB0
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1586287:BBK82 RS38210
gene id: 1586287:BBK82_RS38210
uniprot id: A0A1B2HTA0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1586287:BBK82 RS28470
gene id: 1586287:BBK82_RS28470
uniprot id: A0A1B2HNV7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1586287:BBK82 RS35985
gene id: 1586287:BBK82_RS35985
uniprot id: A0A1B2HSE8
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS04060
gene id: 1586287:BBK82_RS04060
uniprot id: A0A1B2HXP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1586287:BBK82 RS36475
gene id: 1586287:BBK82_RS36475
uniprot id: A0A1B2HSJ5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS40245
gene id: 1586287:BBK82_RS40245
uniprot id: A0A1B2HU61
names: Similarity
messages: Belongs to the cytochrome P450 family.

1586287:BBK82 RS42655
gene id: 1586287:BBK82_RS42655
uniprot id: A0A1B2HVF5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1586287:BBK82 RS16395
gene id: 1586287:BBK82_RS16395
uniprot id: A0A1B2HI69
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1586287:BBK82 RS35270
gene id: 1586287:BBK82_RS35270
uniprot id: A0A1B2HS33
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS18765
gene id: 1586287:BBK82_RS18765
uniprot id: A0A1B2HJC1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1586287:BBK82 RS17795
gene id: 1586287:BBK82_RS17795
uniprot id: A0A1B2HIT5
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1586287:BBK82 RS16830
gene id: 1586287:BBK82_RS16830
uniprot id: A0A1B2HIC8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1586287:BBK82 RS47100
gene id: 1586287:BBK82_RS47100
uniprot id: A0A1B2I0X1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1586287:BBK82 RS00500
gene id: 1586287:BBK82_RS00500
uniprot id: A0A1B2HAN7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1586287:BBK82 RS00935
gene id: 1586287:BBK82_RS00935
uniprot id: A0A1B2HAV5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1586287:BBK82 RS10130
gene id: 1586287:BBK82_RS10130
uniprot id: A0A1B2HF92
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

1586287:BBK82 RS31315
gene id: 1586287:BBK82_RS31315
uniprot id: A0A1B2HS32
names: Similarity
messages: Belongs to the YciI family.

1586287:BBK82 RS09640
gene id: 1586287:BBK82_RS09640
uniprot id: A0A1B2HF09
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS39050
gene id: 1586287:BBK82_RS39050
uniprot id: A0A1B2HTT2
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1586287:BBK82 RS17810
gene id: 1586287:BBK82_RS17810
uniprot id: A0A1B2HIW6
names: Similarity
messages: Belongs to the WXG100 family.

1586287:BBK82 RS45970
gene id: 1586287:BBK82_RS45970
uniprot id: A0A1B2HWW3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1586287:BBK82 RS27005
gene id: 1586287:BBK82_RS27005
uniprot id: A0A1B2HN85
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS36255
gene id: 1586287:BBK82_RS36255
uniprot id: A0A1B2HSH9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS04935
gene id: 1586287:BBK82_RS04935
uniprot id: A0A1B2HCS5
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

1586287:BBK82 RS16675
gene id: 1586287:BBK82_RS16675
uniprot id: A0A1B2HYM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1586287:BBK82 RS46045
gene id: 1586287:BBK82_RS46045
uniprot id: A0A1B2HWU4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1586287:BBK82 RS23970
gene id: 1586287:BBK82_RS23970
uniprot id: A0A1B2HZ56
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1586287:BBK82 RS34895
gene id: 1586287:BBK82_RS34895
uniprot id: A0A1B2HRQ1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS29070
gene id: 1586287:BBK82_RS29070
uniprot id: A0A1B2HP57
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

1586287:BBK82 RS45875
gene id: 1586287:BBK82_RS45875
uniprot id: A0A1B2HWS8
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1586287:BBK82 RS26065
gene id: 1586287:BBK82_RS26065
uniprot id: A0A1B2HMT7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1586287:BBK82 RS44100
gene id: 1586287:BBK82_RS44100
uniprot id: A0A1B2HW06
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS39715
gene id: 1586287:BBK82_RS39715
uniprot id: A0A1B2I0B0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

1586287:BBK82 RS29890
gene id: 1586287:BBK82_RS29890
uniprot id: A0A1B2HZL1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1586287:BBK82 RS14950
gene id: 1586287:BBK82_RS14950
uniprot id: A0A1B2HHI8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS21255
gene id: 1586287:BBK82_RS21255
uniprot id: A0A1B2HKG1
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS20105
gene id: 1586287:BBK82_RS20105
uniprot id: A0A1B2HJV5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS35915
gene id: 1586287:BBK82_RS35915
uniprot id: A0A1B2HSB7
names: Similarity
messages: Belongs to the thioesterase family.

1586287:BBK82 RS18580
gene id: 1586287:BBK82_RS18580
uniprot id: A0A1B2HJ76
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1586287:BBK82 RS18815
gene id: 1586287:BBK82_RS18815
uniprot id: A0A1B2HYS3
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1586287:BBK82 RS25900
gene id: 1586287:BBK82_RS25900
uniprot id: A0A1B2HMN5
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1586287:BBK82 RS01665
gene id: 1586287:BBK82_RS01665
uniprot id: A0A1B2HB86
names: Similarity
messages: Belongs to the peptidase S15 family.

1586287:BBK82 RS29815
gene id: 1586287:BBK82_RS29815
uniprot id: A0A1B2HPH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1586287:BBK82 RS34045
gene id: 1586287:BBK82_RS34045
uniprot id: A0A1B2HRG4
names: Similarity
messages: Belongs to the peptidase S8 family.

1586287:BBK82 RS31645
gene id: 1586287:BBK82_RS31645
uniprot id: A0A1B2HQB4
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

1586287:BBK82 RS41595
gene id: 1586287:BBK82_RS41595
uniprot id: A0A1B2HUX5
names: Similarity
messages: Belongs to the NodU/CmcH family.

1586287:BBK82 RS22715
gene id: 1586287:BBK82_RS22715
uniprot id: A0A1B2HL55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1586287:BBK82 RS50195
gene id: 1586287:BBK82_RS50195
uniprot id: A0A1B2HGW5
names: Similarity
messages: Belongs to the mycobacterial PPE family.

1586287:BBK82 RS32765
gene id: 1586287:BBK82_RS32765
uniprot id: A0A1B2HQX2
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS38420
gene id: 1586287:BBK82_RS38420
uniprot id: A0A1B2HTG5
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

1586287:BBK82 RS15805
gene id: 1586287:BBK82_RS15805
uniprot id: A0A1B2HHX6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1586287:BBK82 RS44325
gene id: 1586287:BBK82_RS44325
uniprot id: A0A1B2HW65
names: Subcellular Location Annotation
messages: Cytoplasm

1586287:BBK82 RS28430
gene id: 1586287:BBK82_RS28430
uniprot id: A0A1B2HNU2
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1586287:BBK82 RS45240
gene id: 1586287:BBK82_RS45240
uniprot id: A0A1B2HWI8
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS14320
gene id: 1586287:BBK82_RS14320
uniprot id: A0A1B2HH68
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS45730
gene id: 1586287:BBK82_RS45730
uniprot id: A0A1B2HWP5
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1586287:BBK82 RS43350
gene id: 1586287:BBK82_RS43350
uniprot id: A0A1B2HVK4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1586287:BBK82 RS28740
gene id: 1586287:BBK82_RS28740
uniprot id: A0A1B2HP01
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1586287:BBK82 RS39205
gene id: 1586287:BBK82_RS39205
uniprot id: A0A1B2HTV6
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

1586287:BBK82 RS28645
gene id: 1586287:BBK82_RS28645
uniprot id: A0A1B2HNY1
names: Similarity
messages: Belongs to the DEAD box helicase family.

1586287:BBK82 RS17380
gene id: 1586287:BBK82_RS17380
uniprot id: A0A1B2HIM3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1586287:BBK82 RS22575
gene id: 1586287:BBK82_RS22575
uniprot id: A0A1B2HL48
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS22830
gene id: 1586287:BBK82_RS22830
uniprot id: A0A1B2HZ24
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS32330
gene id: 1586287:BBK82_RS32330
uniprot id: A0A1B2HQR9
names: Similarity
messages: Belongs to the TPP enzyme family.

1586287:BBK82 RS51115
gene id: 1586287:BBK82_RS51115
uniprot id: A0A1B2HUI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS06000
gene id: 1586287:BBK82_RS06000
uniprot id: A0A1B2HDB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

1586287:BBK82 RS43880
gene id: 1586287:BBK82_RS43880
uniprot id: A0A1B2HVT4
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1586287:BBK82 RS10480
gene id: 1586287:BBK82_RS10480
uniprot id: A0A1B2HFC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS40205
gene id: 1586287:BBK82_RS40205
uniprot id: A0A1B2HU64
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS18425
gene id: 1586287:BBK82_RS18425
uniprot id: A0A1B2HJ29
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1586287:BBK82 RS45945
gene id: 1586287:BBK82_RS45945
uniprot id: A0A1B2HWU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1586287:BBK82 RS40350
gene id: 1586287:BBK82_RS40350
uniprot id: A0A1B2I0B5
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS04580
gene id: 1586287:BBK82_RS04580
uniprot id: A0A1B2HCM3
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1586287:BBK82 RS41590
gene id: 1586287:BBK82_RS41590
uniprot id: A0A1B2HUT9
names: Similarity
messages: Belongs to the cytochrome P450 family.

1586287:BBK82 RS45880
gene id: 1586287:BBK82_RS45880
uniprot id: A0A1B2HWW4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS13845
gene id: 1586287:BBK82_RS13845
uniprot id: A0A1B2HY88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

1586287:BBK82 RS01585
gene id: 1586287:BBK82_RS01585
uniprot id: A0A1B2HB84
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1586287:BBK82 RS01480
gene id: 1586287:BBK82_RS01480
uniprot id: A0A1B2HB57
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1586287:BBK82 RS27250
gene id: 1586287:BBK82_RS27250
uniprot id: A0A1B2HNE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1586287:BBK82 RS27100
gene id: 1586287:BBK82_RS27100
uniprot id: A0A1B2HNC5
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

1586287:BBK82 RS01685
gene id: 1586287:BBK82_RS01685
uniprot id: A0A1B2HBA5
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1586287:BBK82 RS08350
gene id: 1586287:BBK82_RS08350
uniprot id: A0A1B2HEE4
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

1586287:BBK82 RS16310
gene id: 1586287:BBK82_RS16310
uniprot id: A0A1B2HI34
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1586287:BBK82 RS04830
gene id: 1586287:BBK82_RS04830
uniprot id: A0A1B2HCP4
names: Similarity
messages: Belongs to the peptidase S9A family.

1586287:BBK82 RS45940
gene id: 1586287:BBK82_RS45940
uniprot id: A0A1B2HWV9
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1586287:BBK82 RS41615
gene id: 1586287:BBK82_RS41615
uniprot id: A0A1B2HUS5
names: Similarity
messages: In the C-terminal section; belongs to the anthranilate synthase component I family.

1586287:BBK82 RS17865
gene id: 1586287:BBK82_RS17865
uniprot id: A0A1B2HIX8
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1586287:BBK82 RS33430
gene id: 1586287:BBK82_RS33430
uniprot id: A0A1B2HR71
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

1586287:BBK82 RS30630
gene id: 1586287:BBK82_RS30630
uniprot id: A0A1B2HPY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1586287:BBK82 RS21090
gene id: 1586287:BBK82_RS21090
uniprot id: A0A1B2HKC8
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1586287:BBK82 RS40055
gene id: 1586287:BBK82_RS40055
uniprot id: A0A1B2HU37
names: Similarity
messages: Belongs to the thioesterase family.

1586287:BBK82 RS41700
gene id: 1586287:BBK82_RS41700
uniprot id: A0A1B2I0E5
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1586287:BBK82 RS06660
gene id: 1586287:BBK82_RS06660
uniprot id: A0A1B2HDK4
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS21265
gene id: 1586287:BBK82_RS21265
uniprot id: A0A1B2HKG5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS16550
gene id: 1586287:BBK82_RS16550
uniprot id: A0A1B2HI91
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS17575
gene id: 1586287:BBK82_RS17575
uniprot id: A0A1B2HIN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1586287:BBK82 RS13000
gene id: 1586287:BBK82_RS13000
uniprot id: A0A1B2HGL6
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1586287:BBK82 RS39635
gene id: 1586287:BBK82_RS39635
uniprot id: A0A1B2HTX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS39580
gene id: 1586287:BBK82_RS39580
uniprot id: A0A1B2HU10
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1586287:BBK82 RS23825
gene id: 1586287:BBK82_RS23825
uniprot id: A0A1B2HLP2
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

1586287:BBK82 RS11115
gene id: 1586287:BBK82_RS11115
uniprot id: A0A1B2HFN7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1586287:BBK82 RS19800
gene id: 1586287:BBK82_RS19800
uniprot id: A0A1B2HJQ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1586287:BBK82 RS17415
gene id: 1586287:BBK82_RS17415
uniprot id: A0A1B2HIN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1586287:BBK82 RS23665
gene id: 1586287:BBK82_RS23665
uniprot id: A0A1B2HLN5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1586287:BBK82 RS19090
gene id: 1586287:BBK82_RS19090
uniprot id: A0A1B2HJG3
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS37010
gene id: 1586287:BBK82_RS37010
uniprot id: A0A1B2HSR6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1586287:BBK82 RS18770
gene id: 1586287:BBK82_RS18770
uniprot id: A0A1B2HJB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

1586287:BBK82 RS44635
gene id: 1586287:BBK82_RS44635
uniprot id: A0A1B2HW73
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1586287:BBK82 RS23235
gene id: 1586287:BBK82_RS23235
uniprot id: A0A1B2HLE6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1586287:BBK82 RS36780
gene id: 1586287:BBK82_RS36780
uniprot id: A0A1B2HSM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

1586287:BBK82 RS10260
gene id: 1586287:BBK82_RS10260
uniprot id: A0A1B2HFA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS10490
gene id: 1586287:BBK82_RS10490
uniprot id: A0A1B2HY24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1586287:BBK82 RS35245
gene id: 1586287:BBK82_RS35245
uniprot id: A0A1B2HS15
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1586287:BBK82 RS24625
gene id: 1586287:BBK82_RS24625
uniprot id: A0A1B2HM40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1586287:BBK82 RS23550
gene id: 1586287:BBK82_RS23550
uniprot id: A0A1B2HLL6
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1586287:BBK82 RS23530
gene id: 1586287:BBK82_RS23530
uniprot id: A0A1B2HLI7
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS44850
gene id: 1586287:BBK82_RS44850
uniprot id: A0A1B2HW96
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1586287:BBK82 RS15635
gene id: 1586287:BBK82_RS15635
uniprot id: A0A1B2HHS7
names: Similarity
messages: Belongs to the YciI family.

1586287:BBK82 RS32155
gene id: 1586287:BBK82_RS32155
uniprot id: A0A1B2HQJ4
names: Similarity
messages: Belongs to the peptidase S1 family.

1586287:BBK82 RS25345
gene id: 1586287:BBK82_RS25345
uniprot id: A0A1B2HMF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1586287:BBK82 RS09355
gene id: 1586287:BBK82_RS09355
uniprot id: A0A1B2HEU4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS38360
gene id: 1586287:BBK82_RS38360
uniprot id: A0A1B2HTD3
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS04365
gene id: 1586287:BBK82_RS04365
uniprot id: A0A1B2HXK8
names: Subcellular Location Annotation
messages: Cytoplasm

1586287:BBK82 RS08385
gene id: 1586287:BBK82_RS08385
uniprot id: A0A1B2HED3
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1586287:BBK82 RS13350
gene id: 1586287:BBK82_RS13350
uniprot id: A0A1B2HGR9
names: Similarity
messages: Belongs to the YciI family.

1586287:BBK82 RS11315
gene id: 1586287:BBK82_RS11315
uniprot id: A0A1B2HFT2
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1586287:BBK82 RS18715
gene id: 1586287:BBK82_RS18715
uniprot id: A0A1B2HJC0
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1586287:BBK82 RS41040
gene id: 1586287:BBK82_RS41040
uniprot id: A0A1B2I0C6
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS03320
gene id: 1586287:BBK82_RS03320
uniprot id: A0A1B2HBZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

1586287:BBK82 RS07355
gene id: 1586287:BBK82_RS07355
uniprot id: A0A1B2HDW2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1586287:BBK82 RS23815
gene id: 1586287:BBK82_RS23815
uniprot id: A0A1B2HLP4
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1586287:BBK82 RS01515
gene id: 1586287:BBK82_RS01515
uniprot id: A0A1B2HB49
names: Similarity
messages: Belongs to the DapA family.

1586287:BBK82 RS31960
gene id: 1586287:BBK82_RS31960
uniprot id: A0A1B2HQI5
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1586287:BBK82 RS23700
gene id: 1586287:BBK82_RS23700
uniprot id: A0A1B2HLM5
names: Similarity
messages: Belongs to the CsoR family.

1586287:BBK82 RS12165
gene id: 1586287:BBK82_RS12165
uniprot id: A0A1B2HG65
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1586287:BBK82 RS10045
gene id: 1586287:BBK82_RS10045
uniprot id: A0A1B2HY45
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1586287:BBK82 RS35685
gene id: 1586287:BBK82_RS35685
uniprot id: A0A1B2HS98
names: Similarity
messages: Belongs to the amidinotransferase family.

1586287:BBK82 RS08455
gene id: 1586287:BBK82_RS08455
uniprot id: A0A1B2HEE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

1586287:BBK82 RS38705
gene id: 1586287:BBK82_RS38705
uniprot id: A0A1B2HTL2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1586287:BBK82 RS06175
gene id: 1586287:BBK82_RS06175
uniprot id: A0A1B2HDG9
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1586287:BBK82 RS30290
gene id: 1586287:BBK82_RS30290
uniprot id: A0A1B2HPQ1
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1586287:BBK82 RS19630
gene id: 1586287:BBK82_RS19630
uniprot id: A0A1B2HJP5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1586287:BBK82 RS41090
gene id: 1586287:BBK82_RS41090
uniprot id: A0A1B2HUN5
names: Similarity
messages: Belongs to the TPP enzyme family.

1586287:BBK82 RS34160
gene id: 1586287:BBK82_RS34160
uniprot id: A0A1B2HRF8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1586287:BBK82 RS13965
gene id: 1586287:BBK82_RS13965
uniprot id: A0A1B2HH09
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

1586287:BBK82 RS37410
gene id: 1586287:BBK82_RS37410
uniprot id: A0A1B2HSZ0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1586287:BBK82 RS30905
gene id: 1586287:BBK82_RS30905
uniprot id: A0A1B2HPY8
names: Similarity
messages: Belongs to the cytochrome P450 family.

1586287:BBK82 RS42110
gene id: 1586287:BBK82_RS42110
uniprot id: A0A1B2I0M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1586287:BBK82 RS29610
gene id: 1586287:BBK82_RS29610
uniprot id: A0A1B2HPC9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS40400
gene id: 1586287:BBK82_RS40400
uniprot id: A0A1B2HU87
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1586287:BBK82 RS21645
gene id: 1586287:BBK82_RS21645
uniprot id: A0A1B2HKN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1586287:BBK82 RS42710
gene id: 1586287:BBK82_RS42710
uniprot id: A0A1B2HVC2
names: Similarity
messages: Belongs to the FPG family.

1586287:BBK82 RS23635
gene id: 1586287:BBK82_RS23635
uniprot id: A0A1B2HLL7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS06340
gene id: 1586287:BBK82_RS06340
uniprot id: A0A1B2HDE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS08320
gene id: 1586287:BBK82_RS08320
uniprot id: A0A1B2HEC8
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS38620
gene id: 1586287:BBK82_RS38620
uniprot id: A0A1B2HTH4
names: Subcellular Location Annotation
messages: Cytoplasm

1586287:BBK82 RS32625
gene id: 1586287:BBK82_RS32625
uniprot id: A0A1B2HZM6
names: Similarity
messages: Belongs to the universal stress protein A family.

1586287:BBK82 RS01485
gene id: 1586287:BBK82_RS01485
uniprot id: A0A1B2HB63
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1586287:BBK82 RS44655
gene id: 1586287:BBK82_RS44655
uniprot id: A0A1B2HW89
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS12495
gene id: 1586287:BBK82_RS12495
uniprot id: A0A1B2HGB7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1586287:BBK82 RS12840
gene id: 1586287:BBK82_RS12840
uniprot id: A0A1B2HGI6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS31470
gene id: 1586287:BBK82_RS31470
uniprot id: A0A1B2HQC8
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

1586287:BBK82 RS02260
gene id: 1586287:BBK82_RS02260
uniprot id: A0A1B2HBK4
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

1586287:BBK82 RS22220
gene id: 1586287:BBK82_RS22220
uniprot id: A0A1B2HKY3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1586287:BBK82 RS36310
gene id: 1586287:BBK82_RS36310
uniprot id: A0A1B2HSC8
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS21995
gene id: 1586287:BBK82_RS21995
uniprot id: A0A1B2HKT9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1586287:BBK82 RS19730
gene id: 1586287:BBK82_RS19730
uniprot id: A0A1B2HJR2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1586287:BBK82 RS20665
gene id: 1586287:BBK82_RS20665
uniprot id: A0A1B2HYS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1586287:BBK82 RS39825
gene id: 1586287:BBK82_RS39825
uniprot id: A0A1B2HU57
names: Similarity
messages: Belongs to the peptidase C56 family.

1586287:BBK82 RS32800
gene id: 1586287:BBK82_RS32800
uniprot id: A0A1B2HQU3
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS15475
gene id: 1586287:BBK82_RS15475
uniprot id: A0A1B2HHP6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS22590
gene id: 1586287:BBK82_RS22590
uniprot id: A0A1B2HL38
names: Similarity
messages: Belongs to the ribF family.

1586287:BBK82 RS14555
gene id: 1586287:BBK82_RS14555
uniprot id: A0A1B2HHD6
names: Similarity
messages: Belongs to the ParB family.

1586287:BBK82 RS30735
gene id: 1586287:BBK82_RS30735
uniprot id: A0A1B2HPX1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

1586287:BBK82 RS00665
gene id: 1586287:BBK82_RS00665
uniprot id: A0A1B2HAQ9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS41665
gene id: 1586287:BBK82_RS41665
uniprot id: A0A1B2HUY6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1586287:BBK82 RS07120
gene id: 1586287:BBK82_RS07120
uniprot id: A0A1B2HDT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1586287:BBK82 RS13255
gene id: 1586287:BBK82_RS13255
uniprot id: A0A1B2HGS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1586287:BBK82 RS21005
gene id: 1586287:BBK82_RS21005
uniprot id: A0A1B2HKF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

1586287:BBK82 RS32480
gene id: 1586287:BBK82_RS32480
uniprot id: A0A1B2HQP3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1586287:BBK82 RS20540
gene id: 1586287:BBK82_RS20540
uniprot id: A0A1B2HK49
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1586287:BBK82 RS19585
gene id: 1586287:BBK82_RS19585
uniprot id: A0A1B2HJQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS14865
gene id: 1586287:BBK82_RS14865
uniprot id: A0A1B2HHG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1586287:BBK82 RS17590
gene id: 1586287:BBK82_RS17590
uniprot id: A0A1B2HIS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1586287:BBK82 RS13315
gene id: 1586287:BBK82_RS13315
uniprot id: A0A1B2HGR2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1586287:BBK82 RS03985
gene id: 1586287:BBK82_RS03985
uniprot id: A0A1B2HCD5
names: Similarity
messages: Belongs to the TPP enzyme family.

1586287:BBK82 RS22840
gene id: 1586287:BBK82_RS22840
uniprot id: A0A1B2HL73
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS02525
gene id: 1586287:BBK82_RS02525
uniprot id: A0A1B2HBK9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS31985
gene id: 1586287:BBK82_RS31985
uniprot id: A0A1B2HQK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1586287:BBK82 RS31450
gene id: 1586287:BBK82_RS31450
uniprot id: A0A1B2HZJ4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS22310
gene id: 1586287:BBK82_RS22310
uniprot id: A0A1B2HL08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Mitochondrion matrix

1586287:BBK82 RS13735
gene id: 1586287:BBK82_RS13735
uniprot id: A0A1B2HGX6
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

1586287:BBK82 RS41570
gene id: 1586287:BBK82_RS41570
uniprot id: A0A1B2HUV8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1586287:BBK82 RS43415
gene id: 1586287:BBK82_RS43415
uniprot id: A0A1B2HVQ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1586287:BBK82 RS10305
gene id: 1586287:BBK82_RS10305
uniprot id: A0A1B2HFB6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1586287:BBK82 RS19220
gene id: 1586287:BBK82_RS19220
uniprot id: A0A1B2HJJ5
names: Similarity
messages: Belongs to the UPF0434 family.

1586287:BBK82 RS14580
gene id: 1586287:BBK82_RS14580
uniprot id: A0A1B2HH96
names: Similarity
messages: Belongs to the thioredoxin family.

1586287:BBK82 RS39740
gene id: 1586287:BBK82_RS39740
uniprot id: A0A1B2HU26
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS37465
gene id: 1586287:BBK82_RS37465
uniprot id: A0A1B2HSZ3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS00370
gene id: 1586287:BBK82_RS00370
uniprot id: A0A1B2HAL7
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS17535
gene id: 1586287:BBK82_RS17535
uniprot id: A0A1B2HIN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1586287:BBK82 RS32295
gene id: 1586287:BBK82_RS32295
uniprot id: A0A1B2HZL3
names: Similarity
messages: Belongs to the EspG family.

1586287:BBK82 RS40145
gene id: 1586287:BBK82_RS40145
uniprot id: A0A1B2HUA2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1586287:BBK82 RS02140
gene id: 1586287:BBK82_RS02140
uniprot id: A0A1B2HBG6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1586287:BBK82 RS43840
gene id: 1586287:BBK82_RS43840
uniprot id: A0A1B2HVW0
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1586287:BBK82 RS17770
gene id: 1586287:BBK82_RS17770
uniprot id: A0A1B2HIS7
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1586287:BBK82 RS17920
gene id: 1586287:BBK82_RS17920
uniprot id: A0A1B2HIW2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1586287:BBK82 RS32255
gene id: 1586287:BBK82_RS32255
uniprot id: A0A1B2HQL4
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

1586287:BBK82 RS47105
gene id: 1586287:BBK82_RS47105
uniprot id: A0A1B2HX87
names: Similarity
messages: Belongs to the cytochrome P450 family.

1586287:BBK82 RS19640
gene id: 1586287:BBK82_RS19640
uniprot id: A0A1B2HYV5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1586287:BBK82 RS16780
gene id: 1586287:BBK82_RS16780
uniprot id: A0A1B2HIC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1586287:BBK82 RS37800
gene id: 1586287:BBK82_RS37800
uniprot id: A0A1B2HT68
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1586287:BBK82 RS32510
gene id: 1586287:BBK82_RS32510
uniprot id: A0A1B2HQT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1586287:BBK82 RS20525
gene id: 1586287:BBK82_RS20525
uniprot id: A0A1B2HK64
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1586287:BBK82 RS39470
gene id: 1586287:BBK82_RS39470
uniprot id: A0A1B2HTY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

1586287:BBK82 RS16595
gene id: 1586287:BBK82_RS16595
uniprot id: A0A1B2HI87
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1586287:BBK82 RS27230
gene id: 1586287:BBK82_RS27230
uniprot id: A0A1B2HNB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1586287:BBK82 RS34145
gene id: 1586287:BBK82_RS34145
uniprot id: A0A1B2HRJ1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1586287:BBK82 RS43420
gene id: 1586287:BBK82_RS43420
uniprot id: A0A1B2I0P1
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS13925
gene id: 1586287:BBK82_RS13925
uniprot id: A0A1B2HYE6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1586287:BBK82 RS04515
gene id: 1586287:BBK82_RS04515
uniprot id: A0A1B2HCJ6
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS39160
gene id: 1586287:BBK82_RS39160
uniprot id: A0A1B2HTQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases.
messages: Periplasm
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

1586287:BBK82 RS04640
gene id: 1586287:BBK82_RS04640
uniprot id: A0A1B2HCN2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1586287:BBK82 RS35230
gene id: 1586287:BBK82_RS35230
uniprot id: A0A1B2HRZ4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1586287:BBK82 RS24115
gene id: 1586287:BBK82_RS24115
uniprot id: A0A1B2HLW5
names: Subcellular Location Annotation
messages: Membrane

1586287:BBK82 RS25855
gene id: 1586287:BBK82_RS25855
uniprot id: A0A1B2HMQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1586287:BBK82 RS34640
gene id: 1586287:BBK82_RS34640
uniprot id: A0A1B2HRL7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1586287:BBK82 RS03600
gene id: 1586287:BBK82_RS03600
uniprot id: A0A1B2HC48
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1586287:BBK82 RS43045
gene id: 1586287:BBK82_RS43045
uniprot id: A0A1B2HVG2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1586287:BBK82 RS22470
gene id: 1586287:BBK82_RS22470
uniprot id: A0A1B2HL25
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1586287:BBK82 RS18125
gene id: 1586287:BBK82_RS18125
uniprot id: A0A1B2HIY8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1586287:BBK82 RS12000
gene id: 1586287:BBK82_RS12000
uniprot id: A0A1B2HYA3
names: Similarity
messages: Belongs to the peptidase S1 family.

1586287:BBK82 RS23600
gene id: 1586287:BBK82_RS23600
uniprot id: A0A1B2HLK5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1586287:BBK82 RS20575
gene id: 1586287:BBK82_RS20575
uniprot id: A0A1B2HK91
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1586287:BBK82 RS29985
gene id: 1586287:BBK82_RS29985
uniprot id: A0A1B2HPN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1586287:BBK82 RS09410
gene id: 1586287:BBK82_RS09410
uniprot id: A0A1B2HEW6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1586287:BBK82 RS27410
gene id: 1586287:BBK82_RS27410
uniprot id: A0A1B2HNE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1586287:BBK82 RS02145
gene id: 1586287:BBK82_RS02145
uniprot id: A0A1B2HBF2
names: Caution
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1586287:BBK82 RS42640
gene id: 1586287:BBK82_RS42640
uniprot id: A0A1B2HV86
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1586287:BBK82 RS01125
gene id: 1586287:BBK82_RS01125
uniprot id: A0A1B2HB03
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1586287:BBK82 RS18790
gene id: 1586287:BBK82_RS18790
uniprot id: A0A1B2HJA5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1586287:BBK82 RS46900
gene id: 1586287:BBK82_RS46900
uniprot id: A0A1B2HXA6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1586287:BBK82 RS45975
gene id: 1586287:BBK82_RS45975
uniprot id: A0A1B2I0R2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1586287:BBK82 RS24515
gene id: 1586287:BBK82_RS24515
uniprot id: A0A1B2HLZ9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1586287:BBK82 RS04130
gene id: 1586287:BBK82_RS04130
uniprot id: A0A1B2HCE3
names: Similarity
messages: Belongs to the barstar family.

1586287:BBK82 RS01130
gene id: 1586287:BBK82_RS01130
uniprot id: A0A1B2HAZ3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1586287:BBK82 RS42070
gene id: 1586287:BBK82_RS42070
uniprot id: A0A1B2HV52
names: Similarity
messages: Belongs to the DSD1 family.

1586287:BBK82 RS07180
gene id: 1586287:BBK82_RS07180
uniprot id: A0A1B2HDU4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1586287:BBK82 RS26745
gene id: 1586287:BBK82_RS26745
uniprot id: A0A1B2HN64
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.