1549858:MC45 RS02650
gene id: 1549858:MC45_RS02650
uniprot id: A0A097ED23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1549858:MC45 RS12485
gene id: 1549858:MC45_RS12485
uniprot id: A0A097EHL8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1549858:MC45 RS01955
gene id: 1549858:MC45_RS01955
uniprot id: A0A097ECS2
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1549858:MC45 RS07935
gene id: 1549858:MC45_RS07935
uniprot id: A0A097EFH2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1549858:MC45 RS10285
gene id: 1549858:MC45_RS10285
uniprot id: A0A097EGL0
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1549858:MC45 RS10915
gene id: 1549858:MC45_RS10915
uniprot id: A0A097EGV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS14310
gene id: 1549858:MC45_RS14310
uniprot id: A0A097EIG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

1549858:MC45 RS03910
gene id: 1549858:MC45_RS03910
uniprot id: A0A097EDM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1549858:MC45 RS14840
gene id: 1549858:MC45_RS14840
uniprot id: A0A097EIP7
names: Similarity
messages: Belongs to the YoeB family.

1549858:MC45 RS11735
gene id: 1549858:MC45_RS11735
uniprot id: A0A097EH95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1549858:MC45 RS10930
gene id: 1549858:MC45_RS10930
uniprot id: A0A097EGV2
names: Similarity
messages: Belongs to the peptidase S66 family.

1549858:MC45 RS10130
gene id: 1549858:MC45_RS10130
uniprot id: A0A097EGG9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1549858:MC45 RS09525
gene id: 1549858:MC45_RS09525
uniprot id: A0A097EG69
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS06020
gene id: 1549858:MC45_RS06020
uniprot id: A0A097EEM3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1549858:MC45 RS14960
gene id: 1549858:MC45_RS14960
uniprot id: A0A097EIR2
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS04440
gene id: 1549858:MC45_RS04440
uniprot id: A0A097EDW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1549858:MC45 RS17315
gene id: 1549858:MC45_RS17315
uniprot id: A0A097EJS6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1549858:MC45 RS02095
gene id: 1549858:MC45_RS02095
uniprot id: A0A097EK39
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

1549858:MC45 RS09500
gene id: 1549858:MC45_RS09500
uniprot id: A0A097EG63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1549858:MC45 RS16330
gene id: 1549858:MC45_RS16330
uniprot id: A0A097EJD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

1549858:MC45 RS00505
gene id: 1549858:MC45_RS00505
uniprot id: A0A097EC68
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1549858:MC45 RS10760
gene id: 1549858:MC45_RS10760
uniprot id: A0A097EGR8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1549858:MC45 RS17635
gene id: 1549858:MC45_RS17635
uniprot id: A0A097ELE4
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS10675
gene id: 1549858:MC45_RS10675
uniprot id: A0A097EGQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1549858:MC45 RS10340
gene id: 1549858:MC45_RS10340
uniprot id: A0A097EGM1
names: Similarity
messages: Belongs to the alanine racemase family.

1549858:MC45 RS10720
gene id: 1549858:MC45_RS10720
uniprot id: A0A097EGS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1549858:MC45 RS17700
gene id: 1549858:MC45_RS17700
uniprot id: A0A097ELF5
names: Similarity
messages: Belongs to the asparagine synthetase family.

1549858:MC45 RS13695
gene id: 1549858:MC45_RS13695
uniprot id: A0A097EI58
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS00750
gene id: 1549858:MC45_RS00750
uniprot id: A0A097ECA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1549858:MC45 RS04355
gene id: 1549858:MC45_RS04355
uniprot id: A0A097EDX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1549858:MC45 RS16265
gene id: 1549858:MC45_RS16265
uniprot id: A0A097EJC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1549858:MC45 RS05635
gene id: 1549858:MC45_RS05635
uniprot id: A0A097EEG9
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

1549858:MC45 RS04660
gene id: 1549858:MC45_RS04660
uniprot id: A0A097EE03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1549858:MC45 RS10890
gene id: 1549858:MC45_RS10890
uniprot id: A0A097EGV0
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1549858:MC45 RS14570
gene id: 1549858:MC45_RS14570
uniprot id: A0A097EIK2
names: Similarity
messages: Belongs to the RelE toxin family.

1549858:MC45 RS16435
gene id: 1549858:MC45_RS16435
uniprot id: A0A097EJG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS11175
gene id: 1549858:MC45_RS11175
uniprot id: A0A097EH07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1549858:MC45 RS15455
gene id: 1549858:MC45_RS15455
uniprot id: A0A097EIY5
names: Similarity
messages: Belongs to the aspartokinase family.

1549858:MC45 RS09605
gene id: 1549858:MC45_RS09605
uniprot id: A0A097EG98
names: Similarity
messages: Belongs to the pirin family.

1549858:MC45 RS10035
gene id: 1549858:MC45_RS10035
uniprot id: A0A097EGH2
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1549858:MC45 RS10905
gene id: 1549858:MC45_RS10905
uniprot id: A0A097EGU8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1549858:MC45 RS11880
gene id: 1549858:MC45_RS11880
uniprot id: A0A097EHB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1549858:MC45 RS03605
gene id: 1549858:MC45_RS03605
uniprot id: A0A097EDI2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS12565
gene id: 1549858:MC45_RS12565
uniprot id: A0A097EHN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1549858:MC45 RS07885
gene id: 1549858:MC45_RS07885
uniprot id: A0A097EFG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1549858:MC45 RS08420
gene id: 1549858:MC45_RS08420
uniprot id: A0A097EFS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1549858:MC45 RS14905
gene id: 1549858:MC45_RS14905
uniprot id: A0A097EIQ4
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1549858:MC45 RS17875
gene id: 1549858:MC45_RS17875
uniprot id: A0A097ELF2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

1549858:MC45 RS05310
gene id: 1549858:MC45_RS05310
uniprot id: A0A097EEB1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1549858:MC45 RS12045
gene id: 1549858:MC45_RS12045
uniprot id: A0A097EHF3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1549858:MC45 RS13855
gene id: 1549858:MC45_RS13855
uniprot id: A0A097EI69
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS03140
gene id: 1549858:MC45_RS03140
uniprot id: A0A097EDC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1549858:MC45 RS05725
gene id: 1549858:MC45_RS05725
uniprot id: A0A097EEI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1549858:MC45 RS09630
gene id: 1549858:MC45_RS09630
uniprot id: A0A097EGA2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1549858:MC45 RS11825
gene id: 1549858:MC45_RS11825
uniprot id: A0A097EHD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1549858:MC45 RS18245
gene id: 1549858:MC45_RS18245
uniprot id: A0A097ELK9
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

1549858:MC45 RS08435
gene id: 1549858:MC45_RS08435
uniprot id: A0A097EFP1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1549858:MC45 RS03685
gene id: 1549858:MC45_RS03685
uniprot id: A0A097EDJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

1549858:MC45 RS05780
gene id: 1549858:MC45_RS05780
uniprot id: A0A097EEN0
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

1549858:MC45 RS04820
gene id: 1549858:MC45_RS04820
uniprot id: A0A097EE49
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1549858:MC45 RS02790
gene id: 1549858:MC45_RS02790
uniprot id: A0A097ED59
names: Similarity
messages: Belongs to the peptidase M13 family.

1549858:MC45 RS14850
gene id: 1549858:MC45_RS14850
uniprot id: A0A097EIP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1549858:MC45 RS03835
gene id: 1549858:MC45_RS03835
uniprot id: A0A097EDN7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1549858:MC45 RS02990
gene id: 1549858:MC45_RS02990
uniprot id: A0A097ED96
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1549858:MC45 RS09900
gene id: 1549858:MC45_RS09900
uniprot id: A0A097EGE3
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1549858:MC45 RS02385
gene id: 1549858:MC45_RS02385
uniprot id: A0A097ECZ5
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Proposed to provide activated sulfate for transfer to Nod factor. ATP sulfurylase may be the GTPase, regulating ATP sulfurylase activity.
messages: Sulfate-activating enzymes, NodP and NodQ, may be physically associated.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1549858:MC45 RS00790
gene id: 1549858:MC45_RS00790
uniprot id: A0A097ECB0
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1549858:MC45 RS10160
gene id: 1549858:MC45_RS10160
uniprot id: A0A097EGH6
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1549858:MC45 RS15090
gene id: 1549858:MC45_RS15090
uniprot id: A0A097EIS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1549858:MC45 RS03450
gene id: 1549858:MC45_RS03450
uniprot id: A0A097EDK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1549858:MC45 RS09775
gene id: 1549858:MC45_RS09775
uniprot id: A0A097EGB4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1549858:MC45 RS01775
gene id: 1549858:MC45_RS01775
uniprot id: A0A097ECP3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS09920
gene id: 1549858:MC45_RS09920
uniprot id: A0A097EGD9
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1549858:MC45 RS00825
gene id: 1549858:MC45_RS00825
uniprot id: A0A097ECE4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1549858:MC45 RS08465
gene id: 1549858:MC45_RS08465
uniprot id: A0A097EFP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS14295
gene id: 1549858:MC45_RS14295
uniprot id: A0A097EIG9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1549858:MC45 RS03365
gene id: 1549858:MC45_RS03365
uniprot id: A0A097EDF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1549858:MC45 RS17845
gene id: 1549858:MC45_RS17845
uniprot id: A0A097ELE5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1549858:MC45 RS01865
gene id: 1549858:MC45_RS01865
uniprot id: A0A097ECR0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1549858:MC45 RS00250
gene id: 1549858:MC45_RS00250
uniprot id: A0A097EC36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1549858:MC45 RS06975
gene id: 1549858:MC45_RS06975
uniprot id: A0A097EF23
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1549858:MC45 RS17745
gene id: 1549858:MC45_RS17745
uniprot id: A0A097ELG0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1549858:MC45 RS14525
gene id: 1549858:MC45_RS14525
uniprot id: A0A097EIJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1549858:MC45 RS11750
gene id: 1549858:MC45_RS11750
uniprot id: A0A097EH94
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1549858:MC45 RS12815
gene id: 1549858:MC45_RS12815
uniprot id: A0A097EHR5
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1549858:MC45 RS16340
gene id: 1549858:MC45_RS16340
uniprot id: A0A097EJE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

1549858:MC45 RS17710
gene id: 1549858:MC45_RS17710
uniprot id: A0A097ELD0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1549858:MC45 RS13085
gene id: 1549858:MC45_RS13085
uniprot id: A0A097EHV2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1549858:MC45 RS13505
gene id: 1549858:MC45_RS13505
uniprot id: A0A097EI17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1549858:MC45 RS10505
gene id: 1549858:MC45_RS10505
uniprot id: A0A097EGP5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1549858:MC45 RS03265
gene id: 1549858:MC45_RS03265
uniprot id: A0A097EDC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1549858:MC45 RS11645
gene id: 1549858:MC45_RS11645
uniprot id: A0A097EH72
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1549858:MC45 RS01660
gene id: 1549858:MC45_RS01660
uniprot id: A0A097ECN2
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS00635
gene id: 1549858:MC45_RS00635
uniprot id: A0A097EC87
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1549858:MC45 RS04330
gene id: 1549858:MC45_RS04330
uniprot id: A0A097EDX4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1549858:MC45 RS00345
gene id: 1549858:MC45_RS00345
uniprot id: A0A097EC49
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1549858:MC45 RS09055
gene id: 1549858:MC45_RS09055
uniprot id: A0A097EG08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1549858:MC45 RS04165
gene id: 1549858:MC45_RS04165
uniprot id: A0A097EDT7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS12285
gene id: 1549858:MC45_RS12285
uniprot id: A0A097EHI0
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS09045
gene id: 1549858:MC45_RS09045
uniprot id: A0A097EG00
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1549858:MC45 RS02980
gene id: 1549858:MC45_RS02980
uniprot id: A0A097EDC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1549858:MC45 RS13750
gene id: 1549858:MC45_RS13750
uniprot id: A0A097EI66
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1549858:MC45 RS01905
gene id: 1549858:MC45_RS01905
uniprot id: A0A097ECR5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1549858:MC45 RS04720
gene id: 1549858:MC45_RS04720
uniprot id: A0A097EE14
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1549858:MC45 RS03225
gene id: 1549858:MC45_RS03225
uniprot id: A0A097EDC8
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS12680
gene id: 1549858:MC45_RS12680
uniprot id: A0A097EHP4
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1549858:MC45 RS10525
gene id: 1549858:MC45_RS10525
uniprot id: A0A097EGQ6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1549858:MC45 RS13090
gene id: 1549858:MC45_RS13090
uniprot id: A0A097EHU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1549858:MC45 RS13945
gene id: 1549858:MC45_RS13945
uniprot id: A0A097EI85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1549858:MC45 RS15355
gene id: 1549858:MC45_RS15355
uniprot id: A0A097EIX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Membrane

1549858:MC45 RS10845
gene id: 1549858:MC45_RS10845
uniprot id: A0A097EGT3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1549858:MC45 RS14235
gene id: 1549858:MC45_RS14235
uniprot id: A0A097EID7
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1549858:MC45 RS09145
gene id: 1549858:MC45_RS09145
uniprot id: A0A097EG23
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

1549858:MC45 RS07685
gene id: 1549858:MC45_RS07685
uniprot id: A0A097EKI2
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1549858:MC45 RS02785
gene id: 1549858:MC45_RS02785
uniprot id: A0A097ED56
names: Similarity
messages: Belongs to the peptidase M13 family.

1549858:MC45 RS14150
gene id: 1549858:MC45_RS14150
uniprot id: A0A097EIB9
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1549858:MC45 RS09270
gene id: 1549858:MC45_RS09270
uniprot id: A0A097EG28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1549858:MC45 RS12810
gene id: 1549858:MC45_RS12810
uniprot id: A0A097EHR1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS02485
gene id: 1549858:MC45_RS02485
uniprot id: A0A097ED46
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1549858:MC45 RS14075
gene id: 1549858:MC45_RS14075
uniprot id: A0A097EIC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS17455
gene id: 1549858:MC45_RS17455
uniprot id: A0A097EJU9
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1549858:MC45 RS06695
gene id: 1549858:MC45_RS06695
uniprot id: A0A097EEY0
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

1549858:MC45 RS08400
gene id: 1549858:MC45_RS08400
uniprot id: A0A097EFN6
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS01870
gene id: 1549858:MC45_RS01870
uniprot id: A0A097EK37
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1549858:MC45 RS06315
gene id: 1549858:MC45_RS06315
uniprot id: A0A097EER9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1549858:MC45 RS13815
gene id: 1549858:MC45_RS13815
uniprot id: A0A097EI90
names: Similarity
messages: Belongs to the pyruvate kinase family.

1549858:MC45 RS01465
gene id: 1549858:MC45_RS01465
uniprot id: A0A097ECK7
names: Similarity
messages: Belongs to the Dps family.

1549858:MC45 RS00380
gene id: 1549858:MC45_RS00380
uniprot id: A0A097EC54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1549858:MC45 RS02755
gene id: 1549858:MC45_RS02755
uniprot id: A0A097ED51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1549858:MC45 RS16660
gene id: 1549858:MC45_RS16660
uniprot id: A0A097EJI0
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1549858:MC45 RS16195
gene id: 1549858:MC45_RS16195
uniprot id: A0A097EJB1
names: Similarity
messages: Belongs to the CobH/CbiC family.

1549858:MC45 RS04675
gene id: 1549858:MC45_RS04675
uniprot id: A0A097EK95
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1549858:MC45 RS13745
gene id: 1549858:MC45_RS13745
uniprot id: A0A097EI67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1549858:MC45 RS13660
gene id: 1549858:MC45_RS13660
uniprot id: A0A097EI51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1549858:MC45 RS16210
gene id: 1549858:MC45_RS16210
uniprot id: A0A097EJB9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1549858:MC45 RS12345
gene id: 1549858:MC45_RS12345
uniprot id: A0A097EHM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1549858:MC45 RS07725
gene id: 1549858:MC45_RS07725
uniprot id: A0A097EFE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1549858:MC45 RS02455
gene id: 1549858:MC45_RS02455
uniprot id: A0A097ED02
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1549858:MC45 RS10660
gene id: 1549858:MC45_RS10660
uniprot id: A0A097EGS7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1549858:MC45 RS02440
gene id: 1549858:MC45_RS02440
uniprot id: A0A097ED04
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1549858:MC45 RS08560
gene id: 1549858:MC45_RS08560
uniprot id: A0A097EFR2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1549858:MC45 RS00085
gene id: 1549858:MC45_RS00085
uniprot id: A0A097EC23
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1549858:MC45 RS07695
gene id: 1549858:MC45_RS07695
uniprot id: A0A097EFD4
names: Similarity
messages: Belongs to the peptidase M16 family.

1549858:MC45 RS03875
gene id: 1549858:MC45_RS03875
uniprot id: A0A097EDP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell.

1549858:MC45 RS13610
gene id: 1549858:MC45_RS13610
uniprot id: A0A097EI39
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1549858:MC45 RS13135
gene id: 1549858:MC45_RS13135
uniprot id: A0A097EHX4
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1549858:MC45 RS12185
gene id: 1549858:MC45_RS12185
uniprot id: A0A097EHG6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1549858:MC45 RS12915
gene id: 1549858:MC45_RS12915
uniprot id: A0A097EHT2
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1549858:MC45 RS11180
gene id: 1549858:MC45_RS11180
uniprot id: A0A097EKT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1549858:MC45 RS08160
gene id: 1549858:MC45_RS08160
uniprot id: A0A097EKL3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1549858:MC45 RS15130
gene id: 1549858:MC45_RS15130
uniprot id: A0A097EIV9
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS17105
gene id: 1549858:MC45_RS17105
uniprot id: A0A097EJQ3
names: Similarity
messages: Belongs to the CobT family.

1549858:MC45 RS12505
gene id: 1549858:MC45_RS12505
uniprot id: A0A097EHM4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1549858:MC45 RS09250
gene id: 1549858:MC45_RS09250
uniprot id: A0A097EG22
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS11320
gene id: 1549858:MC45_RS11320
uniprot id: A0A097EH11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1549858:MC45 RS06840
gene id: 1549858:MC45_RS06840
uniprot id: A0A097EF12
names: Similarity
messages: Belongs to the type IB topoisomerase family.

1549858:MC45 RS11685
gene id: 1549858:MC45_RS11685
uniprot id: A0A097EH88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1549858:MC45 RS03885
gene id: 1549858:MC45_RS03885
uniprot id: A0A097EK82
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1549858:MC45 RS04400
gene id: 1549858:MC45_RS04400
uniprot id: A0A097EDY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1549858:MC45 RS13670
gene id: 1549858:MC45_RS13670
uniprot id: A0A097EI50
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

1549858:MC45 RS13580
gene id: 1549858:MC45_RS13580
uniprot id: A0A097EI36
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1549858:MC45 RS18195
gene id: 1549858:MC45_RS18195
uniprot id: A0A097ELK1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1549858:MC45 RS03900
gene id: 1549858:MC45_RS03900
uniprot id: A0A097EDP0
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1549858:MC45 RS10395
gene id: 1549858:MC45_RS10395
uniprot id: A0A097EGN1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1549858:MC45 RS13445
gene id: 1549858:MC45_RS13445
uniprot id: A0A097EI28
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1549858:MC45 RS03275
gene id: 1549858:MC45_RS03275
uniprot id: A0A097EDH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1549858:MC45 RS15240
gene id: 1549858:MC45_RS15240
uniprot id: A0A097EIX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1549858:MC45 RS06035
gene id: 1549858:MC45_RS06035
uniprot id: A0A097EEP0
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

1549858:MC45 RS06200
gene id: 1549858:MC45_RS06200
uniprot id: A0A097EEU7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1549858:MC45 RS08485
gene id: 1549858:MC45_RS08485
uniprot id: A0A097EFQ2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1549858:MC45 RS11050
gene id: 1549858:MC45_RS11050
uniprot id: A0A097EGX1
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

1549858:MC45 RS05855
gene id: 1549858:MC45_RS05855
uniprot id: A0A097EEK2
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1549858:MC45 RS02635
gene id: 1549858:MC45_RS02635
uniprot id: A0A097ED35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS15400
gene id: 1549858:MC45_RS15400
uniprot id: A0A097EIX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1549858:MC45 RS11450
gene id: 1549858:MC45_RS11450
uniprot id: A0A097EH57
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1549858:MC45 RS07560
gene id: 1549858:MC45_RS07560
uniprot id: A0A097EFB5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1549858:MC45 RS03810
gene id: 1549858:MC45_RS03810
uniprot id: A0A097EDL6
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1549858:MC45 RS16865
gene id: 1549858:MC45_RS16865
uniprot id: A0A097EL97
names: Similarity
messages: Belongs to the MQO family.

1549858:MC45 RS05050
gene id: 1549858:MC45_RS05050
uniprot id: A0A097EE89
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1549858:MC45 RS12770
gene id: 1549858:MC45_RS12770
uniprot id: A0A097EHQ2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

1549858:MC45 RS13765
gene id: 1549858:MC45_RS13765
uniprot id: A0A097EI56
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

1549858:MC45 RS07865
gene id: 1549858:MC45_RS07865
uniprot id: A0A097EFK1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS11290
gene id: 1549858:MC45_RS11290
uniprot id: A0A097EH29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1549858:MC45 RS03155
gene id: 1549858:MC45_RS03155
uniprot id: A0A097EK63
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1549858:MC45 RS08345
gene id: 1549858:MC45_RS08345
uniprot id: A0A097EFQ9
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1549858:MC45 RS11830
gene id: 1549858:MC45_RS11830
uniprot id: A0A097EHA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1549858:MC45 RS15075
gene id: 1549858:MC45_RS15075
uniprot id: A0A097EIR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1549858:MC45 RS10925
gene id: 1549858:MC45_RS10925
uniprot id: A0A097EGU6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS10030
gene id: 1549858:MC45_RS10030
uniprot id: A0A097EGF0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS08590
gene id: 1549858:MC45_RS08590
uniprot id: A0A097EFR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1549858:MC45 RS13845
gene id: 1549858:MC45_RS13845
uniprot id: A0A097EI94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1549858:MC45 RS16190
gene id: 1549858:MC45_RS16190
uniprot id: A0A097EJC2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1549858:MC45 RS03455
gene id: 1549858:MC45_RS03455
uniprot id: A0A097EDG8
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1549858:MC45 RS03960
gene id: 1549858:MC45_RS03960
uniprot id: A0A097EDQ0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

1549858:MC45 RS11025
gene id: 1549858:MC45_RS11025
uniprot id: A0A097EGX8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1549858:MC45 RS13190
gene id: 1549858:MC45_RS13190
uniprot id: A0A097EHY3
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS09425
gene id: 1549858:MC45_RS09425
uniprot id: A0A097EG62
names: Similarity
messages: Belongs to the UPF0262 family.

1549858:MC45 RS05265
gene id: 1549858:MC45_RS05265
uniprot id: A0A097EEC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS08575
gene id: 1549858:MC45_RS08575
uniprot id: A0A097EFT5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1549858:MC45 RS07670
gene id: 1549858:MC45_RS07670
uniprot id: A0A097EFH1
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1549858:MC45 RS14755
gene id: 1549858:MC45_RS14755
uniprot id: A0A097EIN7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1549858:MC45 RS16440
gene id: 1549858:MC45_RS16440
uniprot id: A0A097EJE9
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1549858:MC45 RS04515
gene id: 1549858:MC45_RS04515
uniprot id: A0A097EDX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1549858:MC45 RS12850
gene id: 1549858:MC45_RS12850
uniprot id: A0A097EHQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS05865
gene id: 1549858:MC45_RS05865
uniprot id: A0A097EEL5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS03540
gene id: 1549858:MC45_RS03540
uniprot id: A0A097EDJ1
names: Similarity
messages: Belongs to the thioesterase PaaI family.

1549858:MC45 RS02200
gene id: 1549858:MC45_RS02200
uniprot id: A0A097ECV7
names: Similarity
messages: Belongs to the ros/MucR family.

1549858:MC45 RS12785
gene id: 1549858:MC45_RS12785
uniprot id: A0A097EHQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1549858:MC45 RS00890
gene id: 1549858:MC45_RS00890
uniprot id: A0A097ECC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1549858:MC45 RS17870
gene id: 1549858:MC45_RS17870
uniprot id: A0A097ELE9
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1549858:MC45 RS17260
gene id: 1549858:MC45_RS17260
uniprot id: A0A097EJS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

1549858:MC45 RS04990
gene id: 1549858:MC45_RS04990
uniprot id: A0A097EE57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1549858:MC45 RS06920
gene id: 1549858:MC45_RS06920
uniprot id: A0A097EF14
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1549858:MC45 RS04985
gene id: 1549858:MC45_RS04985
uniprot id: A0A097EE80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1549858:MC45 RS13640
gene id: 1549858:MC45_RS13640
uniprot id: A0A097EI44
names: Similarity
messages: Belongs to the CcdB toxin family.

1549858:MC45 RS11820
gene id: 1549858:MC45_RS11820
uniprot id: A0A097EHA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1549858:MC45 RS05305
gene id: 1549858:MC45_RS05305
uniprot id: A0A097EED3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1549858:MC45 RS16730
gene id: 1549858:MC45_RS16730
uniprot id: A0A097EJJ2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1549858:MC45 RS15695
gene id: 1549858:MC45_RS15695
uniprot id: A0A097EJ22
names: Similarity
messages: Belongs to the UxaA family.

1549858:MC45 RS10265
gene id: 1549858:MC45_RS10265
uniprot id: A0A097EGL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1549858:MC45 RS04380
gene id: 1549858:MC45_RS04380
uniprot id: A0A097EDV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1549858:MC45 RS17390
gene id: 1549858:MC45_RS17390
uniprot id: A0A097ELA9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1549858:MC45 RS03945
gene id: 1549858:MC45_RS03945
uniprot id: A0A097EDQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Membrane

1549858:MC45 RS16155
gene id: 1549858:MC45_RS16155
uniprot id: A0A097EJA0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1549858:MC45 RS08600
gene id: 1549858:MC45_RS08600
uniprot id: A0A097EFT6
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1549858:MC45 RS09655
gene id: 1549858:MC45_RS09655
uniprot id: A0A097EGA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

1549858:MC45 RS13050
gene id: 1549858:MC45_RS13050
uniprot id: A0A097EHW6
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1549858:MC45 RS01925
gene id: 1549858:MC45_RS01925
uniprot id: A0A097ECV1
names: Similarity
messages: Belongs to the TlyA family.

1549858:MC45 RS03400
gene id: 1549858:MC45_RS03400
uniprot id: A0A097EDF7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1549858:MC45 RS18280
gene id: 1549858:MC45_RS18280
uniprot id: A0A097ELM6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1549858:MC45 RS07030
gene id: 1549858:MC45_RS07030
uniprot id: A0A097EF80
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1549858:MC45 RS13770
gene id: 1549858:MC45_RS13770
uniprot id: A0A097EI71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1549858:MC45 RS03300
gene id: 1549858:MC45_RS03300
uniprot id: A0A097EDD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS05740
gene id: 1549858:MC45_RS05740
uniprot id: A0A097EEI3
names: Similarity
messages: Belongs to the ArsC family.

1549858:MC45 RS18305
gene id: 1549858:MC45_RS18305
uniprot id: A0A097ELN2
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1549858:MC45 RS13560
gene id: 1549858:MC45_RS13560
uniprot id: A0A097EI30
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1549858:MC45 RS04625
gene id: 1549858:MC45_RS04625
uniprot id: A0A097EE12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS10110
gene id: 1549858:MC45_RS10110
uniprot id: A0A097EGG5
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1549858:MC45 RS18295
gene id: 1549858:MC45_RS18295
uniprot id: A0A097ELM5
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS06015
gene id: 1549858:MC45_RS06015
uniprot id: A0A097EEM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1549858:MC45 RS12180
gene id: 1549858:MC45_RS12180
uniprot id: A0A097EHG2
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1549858:MC45 RS04125
gene id: 1549858:MC45_RS04125
uniprot id: A0A097EDT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1549858:MC45 RS03070
gene id: 1549858:MC45_RS03070
uniprot id: A0A097EK62
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1549858:MC45 RS10655
gene id: 1549858:MC45_RS10655
uniprot id: A0A097EGQ8
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the reversible phosphorylation of pyruvate and phosphate.

1549858:MC45 RS06345
gene id: 1549858:MC45_RS06345
uniprot id: A0A097EES1
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1549858:MC45 RS00895
gene id: 1549858:MC45_RS00895
uniprot id: A0A097ECD3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1549858:MC45 RS12600
gene id: 1549858:MC45_RS12600
uniprot id: A0A097EHN2
names: Similarity
messages: Belongs to the proline racemase family.

1549858:MC45 RS00305
gene id: 1549858:MC45_RS00305
uniprot id: A0A097EC40
names: Similarity
messages: Belongs to the DapA family.

1549858:MC45 RS04850
gene id: 1549858:MC45_RS04850
uniprot id: A0A097EE34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1549858:MC45 RS03335
gene id: 1549858:MC45_RS03335
uniprot id: A0A097EDI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

1549858:MC45 RS12725
gene id: 1549858:MC45_RS12725
uniprot id: A0A097EHQ3
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1549858:MC45 RS05295
gene id: 1549858:MC45_RS05295
uniprot id: A0A097EED7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1549858:MC45 RS10240
gene id: 1549858:MC45_RS10240
uniprot id: A0A097EKR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1549858:MC45 RS10785
gene id: 1549858:MC45_RS10785
uniprot id: A0A097EGU7
names: Similarity
messages: Belongs to the YciI family.

1549858:MC45 RS06520
gene id: 1549858:MC45_RS06520
uniprot id: A0A097EEV9
names: Similarity
messages: Belongs to the RecJ family.

1549858:MC45 RS12530
gene id: 1549858:MC45_RS12530
uniprot id: A0A097EHM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. In Gram-negative bacteria, at least four rings, L, P, S and M are present, whereas Gram-positive bacteria lack the L and P rings. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF build up the proximal portion of the rod with about 6 subunits each. Rod assembly occurs by export via the flagellum-specific pathway of its constituent proteins and by their incorporation into the rod structure in the probable order of FlgB, FlgC, FlgF and FlgG. Another protein, FliE, also assembles onto the stable rod structure.

1549858:MC45 RS17655
gene id: 1549858:MC45_RS17655
uniprot id: A0A097ELC8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1549858:MC45 RS13615
gene id: 1549858:MC45_RS13615
uniprot id: A0A097EI40
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1549858:MC45 RS08065
gene id: 1549858:MC45_RS08065
uniprot id: A0A097EFJ2
names: Function
messages: Acts on leucine, isoleucine and valine.

1549858:MC45 RS10790
gene id: 1549858:MC45_RS10790
uniprot id: A0A097EGS2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1549858:MC45 RS07845
gene id: 1549858:MC45_RS07845
uniprot id: A0A097EFF7
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1549858:MC45 RS14550
gene id: 1549858:MC45_RS14550
uniprot id: A0A097EIJ7
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1549858:MC45 RS00565
gene id: 1549858:MC45_RS00565
uniprot id: A0A097EC78
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

1549858:MC45 RS03405
gene id: 1549858:MC45_RS03405
uniprot id: A0A097EDH1
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1549858:MC45 RS11905
gene id: 1549858:MC45_RS11905
uniprot id: A0A097EHC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
messages: Homotetramer.

1549858:MC45 RS01730
gene id: 1549858:MC45_RS01730
uniprot id: A0A097ECN4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1549858:MC45 RS10230
gene id: 1549858:MC45_RS10230
uniprot id: A0A097EGJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1549858:MC45 RS05750
gene id: 1549858:MC45_RS05750
uniprot id: A0A097EEJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.
messages: Oligomer of 12 subunits arranged in the form of two hexameric ring.

1549858:MC45 RS05560
gene id: 1549858:MC45_RS05560
uniprot id: A0A097EEG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COX15/CtaA family. Type 2 subfamily.
messages: Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
messages: Cell membrane
messages: Interacts with CtaB.
messages: Membrane

1549858:MC45 RS17075
gene id: 1549858:MC45_RS17075
uniprot id: A0A097EJP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

1549858:MC45 RS01340
gene id: 1549858:MC45_RS01340
uniprot id: A0A097ECI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

1549858:MC45 RS12475
gene id: 1549858:MC45_RS12475
uniprot id: A0A097EHL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1549858:MC45 RS07925
gene id: 1549858:MC45_RS07925
uniprot id: A0A097EFH5
names: Similarity
messages: Belongs to the CFA/CMAS family.

1549858:MC45 RS09225
gene id: 1549858:MC45_RS09225
uniprot id: A0A097EG20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein.

1549858:MC45 RS02480
gene id: 1549858:MC45_RS02480
uniprot id: A0A097ED05
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1549858:MC45 RS04135
gene id: 1549858:MC45_RS04135
uniprot id: A0A097EDT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1549858:MC45 RS05975
gene id: 1549858:MC45_RS05975
uniprot id: A0A097EEM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1549858:MC45 RS03635
gene id: 1549858:MC45_RS03635
uniprot id: A0A097EDI5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1549858:MC45 RS04170
gene id: 1549858:MC45_RS04170
uniprot id: A0A097EDU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1549858:MC45 RS05590
gene id: 1549858:MC45_RS05590
uniprot id: A0A097EEG2
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1549858:MC45 RS09375
gene id: 1549858:MC45_RS09375
uniprot id: A0A097EG59
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1549858:MC45 RS11800
gene id: 1549858:MC45_RS11800
uniprot id: A0A097EHC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1549858:MC45 RS05870
gene id: 1549858:MC45_RS05870
uniprot id: A0A097EEP1
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS05760
gene id: 1549858:MC45_RS05760
uniprot id: A0A097EEJ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.

1549858:MC45 RS08970
gene id: 1549858:MC45_RS08970
uniprot id: A0A097EFX6
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1549858:MC45 RS06825
gene id: 1549858:MC45_RS06825
uniprot id: A0A097EEZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

1549858:MC45 RS13420
gene id: 1549858:MC45_RS13420
uniprot id: A0A097EI00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1549858:MC45 RS05030
gene id: 1549858:MC45_RS05030
uniprot id: A0A097EE85
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1549858:MC45 RS09580
gene id: 1549858:MC45_RS09580
uniprot id: A0A097EG94
names: Similarity
messages: Belongs to the AHA1 family.

1549858:MC45 RS02740
gene id: 1549858:MC45_RS02740
uniprot id: A0A097ED44
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1549858:MC45 RS11105
gene id: 1549858:MC45_RS11105
uniprot id: A0A097EGX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1549858:MC45 RS11755
gene id: 1549858:MC45_RS11755
uniprot id: A0A097EHA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1549858:MC45 RS03425
gene id: 1549858:MC45_RS03425
uniprot id: A0A097EDJ9
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1549858:MC45 RS08795
gene id: 1549858:MC45_RS08795
uniprot id: A0A097EFV3
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1549858:MC45 RS17905
gene id: 1549858:MC45_RS17905
uniprot id: A0A097ELF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS05365
gene id: 1549858:MC45_RS05365
uniprot id: A0A097EEB6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1549858:MC45 RS03045
gene id: 1549858:MC45_RS03045
uniprot id: A0A097EDA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1549858:MC45 RS04780
gene id: 1549858:MC45_RS04780
uniprot id: A0A097EE44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

1549858:MC45 RS06395
gene id: 1549858:MC45_RS06395
uniprot id: A0A097EEX9
names: Similarity
messages: Belongs to the SufE family.

1549858:MC45 RS10345
gene id: 1549858:MC45_RS10345
uniprot id: A0A097EGL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1549858:MC45 RS03370
gene id: 1549858:MC45_RS03370
uniprot id: A0A097EDG6
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1549858:MC45 RS09600
gene id: 1549858:MC45_RS09600
uniprot id: A0A097EG82
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1549858:MC45 RS03260
gene id: 1549858:MC45_RS03260
uniprot id: A0A097EDD3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1549858:MC45 RS08375
gene id: 1549858:MC45_RS08375
uniprot id: A0A097EFN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1549858:MC45 RS08870
gene id: 1549858:MC45_RS08870
uniprot id: A0A097EFW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1549858:MC45 RS15295
gene id: 1549858:MC45_RS15295
uniprot id: A0A097EIY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1549858:MC45 RS15410
gene id: 1549858:MC45_RS15410
uniprot id: A0A097EJ05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1549858:MC45 RS00695
gene id: 1549858:MC45_RS00695
uniprot id: A0A097EC97
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1549858:MC45 RS10615
gene id: 1549858:MC45_RS10615
uniprot id: A0A097EGP6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1549858:MC45 RS10065
gene id: 1549858:MC45_RS10065
uniprot id: A0A097EGG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1549858:MC45 RS15305
gene id: 1549858:MC45_RS15305
uniprot id: A0A097EIW1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1549858:MC45 RS13215
gene id: 1549858:MC45_RS13215
uniprot id: A0A097EHY8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1549858:MC45 RS02845
gene id: 1549858:MC45_RS02845
uniprot id: A0A097ED62
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1549858:MC45 RS13940
gene id: 1549858:MC45_RS13940
uniprot id: A0A097EIB2
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS10070
gene id: 1549858:MC45_RS10070
uniprot id: A0A097EGH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1549858:MC45 RS05920
gene id: 1549858:MC45_RS05920
uniprot id: A0A097EEL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1549858:MC45 RS07495
gene id: 1549858:MC45_RS07495
uniprot id: A0A097EFA1
names: Similarity
messages: Belongs to the ros/MucR family.

1549858:MC45 RS05980
gene id: 1549858:MC45_RS05980
uniprot id: A0A097EEL9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1549858:MC45 RS15415
gene id: 1549858:MC45_RS15415
uniprot id: A0A097EIY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1549858:MC45 RS05045
gene id: 1549858:MC45_RS05045
uniprot id: A0A097EE69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1549858:MC45 RS02995
gene id: 1549858:MC45_RS02995
uniprot id: A0A097ED89
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1549858:MC45 RS02625
gene id: 1549858:MC45_RS02625
uniprot id: A0A097ED65
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1549858:MC45 RS10015
gene id: 1549858:MC45_RS10015
uniprot id: A0A097EGF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1549858:MC45 RS00525
gene id: 1549858:MC45_RS00525
uniprot id: A0A097EC71
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1549858:MC45 RS11465
gene id: 1549858:MC45_RS11465
uniprot id: A0A097EH37
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1549858:MC45 RS09535
gene id: 1549858:MC45_RS09535
uniprot id: A0A097EKQ2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1549858:MC45 RS03325
gene id: 1549858:MC45_RS03325
uniprot id: A0A097EDE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OprB family.
messages: Cell outer membrane

1549858:MC45 RS08520
gene id: 1549858:MC45_RS08520
uniprot id: A0A097EFQ3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1549858:MC45 RS09115
gene id: 1549858:MC45_RS09115
uniprot id: A0A097EFZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1549858:MC45 RS11210
gene id: 1549858:MC45_RS11210
uniprot id: A0A097EH05
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1549858:MC45 RS03135
gene id: 1549858:MC45_RS03135
uniprot id: A0A097EK88
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS05065
gene id: 1549858:MC45_RS05065
uniprot id: A0A097EE96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1549858:MC45 RS12385
gene id: 1549858:MC45_RS12385
uniprot id: A0A097EHM5
names: Similarity
messages: Belongs to the DEAD box helicase family.

1549858:MC45 RS09265
gene id: 1549858:MC45_RS09265
uniprot id: A0A097EG40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1549858:MC45 RS06745
gene id: 1549858:MC45_RS06745
uniprot id: A0A097EF36
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

1549858:MC45 RS06235
gene id: 1549858:MC45_RS06235
uniprot id: A0A097EEQ9
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS00945
gene id: 1549858:MC45_RS00945
uniprot id: A0A097ECD7
names: Similarity
messages: Belongs to the PhzF family.

1549858:MC45 RS04570
gene id: 1549858:MC45_RS04570
uniprot id: A0A097EE21
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

1549858:MC45 RS13415
gene id: 1549858:MC45_RS13415
uniprot id: A0A097EI24
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1549858:MC45 RS08720
gene id: 1549858:MC45_RS08720
uniprot id: A0A097EFU5
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1549858:MC45 RS02880
gene id: 1549858:MC45_RS02880
uniprot id: A0A097EDB3
names: Caution
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS09975
gene id: 1549858:MC45_RS09975
uniprot id: A0A097EGE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1549858:MC45 RS02940
gene id: 1549858:MC45_RS02940
uniprot id: A0A097ED73
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS07440
gene id: 1549858:MC45_RS07440
uniprot id: A0A097EF90
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1549858:MC45 RS14600
gene id: 1549858:MC45_RS14600
uniprot id: A0A097EIK4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1549858:MC45 RS11680
gene id: 1549858:MC45_RS11680
uniprot id: A0A097EH81
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1549858:MC45 RS15405
gene id: 1549858:MC45_RS15405
uniprot id: A0A097EIY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1549858:MC45 RS11260
gene id: 1549858:MC45_RS11260
uniprot id: A0A097EH23
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1549858:MC45 RS13915
gene id: 1549858:MC45_RS13915
uniprot id: A0A097EI80
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1549858:MC45 RS16970
gene id: 1549858:MC45_RS16970
uniprot id: A0A097EJM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1549858:MC45 RS06600
gene id: 1549858:MC45_RS06600
uniprot id: A0A097EEW3
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1549858:MC45 RS14035
gene id: 1549858:MC45_RS14035
uniprot id: A0A097EI99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1549858:MC45 RS04835
gene id: 1549858:MC45_RS04835
uniprot id: A0A097EE48
names: Similarity
messages: Belongs to the peptidase M17 family.

1549858:MC45 RS12075
gene id: 1549858:MC45_RS12075
uniprot id: A0A097EHE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

1549858:MC45 RS12895
gene id: 1549858:MC45_RS12895
uniprot id: A0A097EHS1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1549858:MC45 RS05075
gene id: 1549858:MC45_RS05075
uniprot id: A0A097EE95
names: Similarity
messages: Belongs to the YkuD family.

1549858:MC45 RS10995
gene id: 1549858:MC45_RS10995
uniprot id: A0A097EGW2
names: Similarity
messages: Belongs to the ClpX chaperone family. HslU subfamily.

1549858:MC45 RS14205
gene id: 1549858:MC45_RS14205
uniprot id: A0A097EL20
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1549858:MC45 RS03315
gene id: 1549858:MC45_RS03315
uniprot id: A0A097EDE0
names: Similarity
messages: Belongs to the FrmR/RcnR family.

1549858:MC45 RS11715
gene id: 1549858:MC45_RS11715
uniprot id: A0A097EH99
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1549858:MC45 RS12735
gene id: 1549858:MC45_RS12735
uniprot id: A0A097EHS3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

1549858:MC45 RS11655
gene id: 1549858:MC45_RS11655
uniprot id: A0A097EH78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1549858:MC45 RS13120
gene id: 1549858:MC45_RS13120
uniprot id: A0A097EKZ4
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1549858:MC45 RS15325
gene id: 1549858:MC45_RS15325
uniprot id: A0A097EIW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1549858:MC45 RS10565
gene id: 1549858:MC45_RS10565
uniprot id: A0A097EGQ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1549858:MC45 RS12920
gene id: 1549858:MC45_RS12920
uniprot id: A0A097EHS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1549858:MC45 RS11360
gene id: 1549858:MC45_RS11360
uniprot id: A0A097EH40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1549858:MC45 RS10880
gene id: 1549858:MC45_RS10880
uniprot id: A0A097EGU4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1549858:MC45 RS13195
gene id: 1549858:MC45_RS13195
uniprot id: A0A097EHV5
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS03520
gene id: 1549858:MC45_RS03520
uniprot id: A0A097EDG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1549858:MC45 RS14090
gene id: 1549858:MC45_RS14090
uniprot id: A0A097EIA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1549858:MC45 RS11705
gene id: 1549858:MC45_RS11705
uniprot id: A0A097EH91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1549858:MC45 RS02720
gene id: 1549858:MC45_RS02720
uniprot id: A0A097ED80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1549858:MC45 RS17330
gene id: 1549858:MC45_RS17330
uniprot id: A0A097EJT8
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS16355
gene id: 1549858:MC45_RS16355
uniprot id: A0A097EJD2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS06915
gene id: 1549858:MC45_RS06915
uniprot id: A0A097EF16
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1549858:MC45 RS08110
gene id: 1549858:MC45_RS08110
uniprot id: A0A097EFK4
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

1549858:MC45 RS09035
gene id: 1549858:MC45_RS09035
uniprot id: A0A097EFY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1549858:MC45 RS08895
gene id: 1549858:MC45_RS08895
uniprot id: A0A097EFW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS17940
gene id: 1549858:MC45_RS17940
uniprot id: A0A097ELF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1549858:MC45 RS00625
gene id: 1549858:MC45_RS00625
uniprot id: A0A097EC80
names: Similarity
messages: Belongs to the pirin family.

1549858:MC45 RS14095
gene id: 1549858:MC45_RS14095
uniprot id: A0A097EIC6
names: Similarity
messages: Belongs to the GARS family.

1549858:MC45 RS14005
gene id: 1549858:MC45_RS14005
uniprot id: A0A097EIC3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1549858:MC45 RS10560
gene id: 1549858:MC45_RS10560
uniprot id: A0A097EGN8
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1549858:MC45 RS06290
gene id: 1549858:MC45_RS06290
uniprot id: A0A097EES9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1549858:MC45 RS04315
gene id: 1549858:MC45_RS04315
uniprot id: A0A097EDW3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

1549858:MC45 RS15390
gene id: 1549858:MC45_RS15390
uniprot id: A0A097EL52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1549858:MC45 RS14725
gene id: 1549858:MC45_RS14725
uniprot id: A0A097EIN4
names: Function
messages: Multidrug efflux pump.

1549858:MC45 RS04160
gene id: 1549858:MC45_RS04160
uniprot id: A0A097EDV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1549858:MC45 RS07915
gene id: 1549858:MC45_RS07915
uniprot id: A0A097EFH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

1549858:MC45 RS06900
gene id: 1549858:MC45_RS06900
uniprot id: A0A097EF21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1549858:MC45 RS04980
gene id: 1549858:MC45_RS04980
uniprot id: A0A097EE76
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS04015
gene id: 1549858:MC45_RS04015
uniprot id: A0A097EDR7
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1549858:MC45 RS08085
gene id: 1549858:MC45_RS08085
uniprot id: A0A097EFN5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS04320
gene id: 1549858:MC45_RS04320
uniprot id: A0A097EDW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

1549858:MC45 RS12730
gene id: 1549858:MC45_RS12730
uniprot id: A0A097EHP7
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

1549858:MC45 RS04265
gene id: 1549858:MC45_RS04265
uniprot id: A0A097EDT9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1549858:MC45 RS11395
gene id: 1549858:MC45_RS11395
uniprot id: A0A097EH43
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

1549858:MC45 RS17060
gene id: 1549858:MC45_RS17060
uniprot id: A0A097ELA3
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1549858:MC45 RS05525
gene id: 1549858:MC45_RS05525
uniprot id: A0A097EEF7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1549858:MC45 RS14215
gene id: 1549858:MC45_RS14215
uniprot id: A0A097EIE6
names: Similarity
messages: Belongs to the LOG family.

1549858:MC45 RS02585
gene id: 1549858:MC45_RS02585
uniprot id: A0A097ED15
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1549858:MC45 RS15955
gene id: 1549858:MC45_RS15955
uniprot id: A0A097EJ61
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1549858:MC45 RS05260
gene id: 1549858:MC45_RS05260
uniprot id: A0A097EEA2
names: Function
names: Subcellular Location Annotation
messages: Could be a virulence factor.
messages: Secreted

1549858:MC45 RS13900
gene id: 1549858:MC45_RS13900
uniprot id: A0A097EI92
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1549858:MC45 RS02570
gene id: 1549858:MC45_RS02570
uniprot id: A0A097EK53
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1549858:MC45 RS08645
gene id: 1549858:MC45_RS08645
uniprot id: A0A097EFS4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS05900
gene id: 1549858:MC45_RS05900
uniprot id: A0A097EEP5
names: Similarity
messages: Belongs to the DEAD box helicase family.

1549858:MC45 RS06000
gene id: 1549858:MC45_RS06000
uniprot id: A0A097EER8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1549858:MC45 RS13555
gene id: 1549858:MC45_RS13555
uniprot id: A0A097EI31
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1549858:MC45 RS00780
gene id: 1549858:MC45_RS00780
uniprot id: A0A097EK02
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1549858:MC45 RS03250
gene id: 1549858:MC45_RS03250
uniprot id: A0A097EDD2
names: Similarity
messages: Belongs to the peptidase U62 family.

1549858:MC45 RS11595
gene id: 1549858:MC45_RS11595
uniprot id: A0A097EH59
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS03995
gene id: 1549858:MC45_RS03995
uniprot id: A0A097EK83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane

1549858:MC45 RS02840
gene id: 1549858:MC45_RS02840
uniprot id: A0A097ED72
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1549858:MC45 RS13780
gene id: 1549858:MC45_RS13780
uniprot id: A0A097EI73
names: Similarity
messages: Belongs to the UPF0235 family.

1549858:MC45 RS12805
gene id: 1549858:MC45_RS12805
uniprot id: A0A097EHP8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1549858:MC45 RS02335
gene id: 1549858:MC45_RS02335
uniprot id: A0A097ECY8
names: Similarity
messages: Belongs to the peptidase S9C family.

1549858:MC45 RS03350
gene id: 1549858:MC45_RS03350
uniprot id: A0A097EDE6
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1549858:MC45 RS11120
gene id: 1549858:MC45_RS11120
uniprot id: A0A097EGZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1549858:MC45 RS11420
gene id: 1549858:MC45_RS11420
uniprot id: A0A097EH28
names: Cofactor
names: Function
messages: Alkaline phosphatase with broad substrate specificity.
messages: Binds 2 Zn(2+) ions.

1549858:MC45 RS06360
gene id: 1549858:MC45_RS06360
uniprot id: A0A097EET1
names: Similarity
messages: Belongs to the PspA/IM30 family.

1549858:MC45 RS11330
gene id: 1549858:MC45_RS11330
uniprot id: A0A097EH35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1549858:MC45 RS04010
gene id: 1549858:MC45_RS04010
uniprot id: A0A097EDP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1549858:MC45 RS14475
gene id: 1549858:MC45_RS14475
uniprot id: A0A097EII5
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1549858:MC45 RS18450
gene id: 1549858:MC45_RS18450
uniprot id: A0A097ELT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1549858:MC45 RS16165
gene id: 1549858:MC45_RS16165
uniprot id: A0A097EJB8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1549858:MC45 RS03310
gene id: 1549858:MC45_RS03310
uniprot id: A0A097EDI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS17755
gene id: 1549858:MC45_RS17755
uniprot id: A0A097ELD6
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1549858:MC45 RS13905
gene id: 1549858:MC45_RS13905
uniprot id: A0A097EI91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

1549858:MC45 RS15575
gene id: 1549858:MC45_RS15575
uniprot id: A0A097EJ14
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1549858:MC45 RS04140
gene id: 1549858:MC45_RS04140
uniprot id: A0A097EDT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1549858:MC45 RS07835
gene id: 1549858:MC45_RS07835
uniprot id: A0A097EFJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

1549858:MC45 RS13310
gene id: 1549858:MC45_RS13310
uniprot id: A0A097EHY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1549858:MC45 RS17020
gene id: 1549858:MC45_RS17020
uniprot id: A0A097EJN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS04075
gene id: 1549858:MC45_RS04075
uniprot id: A0A097EDU3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

1549858:MC45 RS15925
gene id: 1549858:MC45_RS15925
uniprot id: A0A097EJ78
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1549858:MC45 RS14735
gene id: 1549858:MC45_RS14735
uniprot id: A0A097EIM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1549858:MC45 RS13300
gene id: 1549858:MC45_RS13300
uniprot id: A0A097EHZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1549858:MC45 RS03545
gene id: 1549858:MC45_RS03545
uniprot id: A0A097EDH4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

1549858:MC45 RS10100
gene id: 1549858:MC45_RS10100
uniprot id: A0A097EKQ5
names: Similarity
messages: Belongs to the UPF0758 family.

1549858:MC45 RS07595
gene id: 1549858:MC45_RS07595
uniprot id: A0A097EFC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1549858:MC45 RS14110
gene id: 1549858:MC45_RS14110
uniprot id: A0A097EIC5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1549858:MC45 RS06795
gene id: 1549858:MC45_RS06795
uniprot id: A0A097EEZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1549858:MC45 RS16295
gene id: 1549858:MC45_RS16295
uniprot id: A0A097EJC8
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1549858:MC45 RS12965
gene id: 1549858:MC45_RS12965
uniprot id: A0A097EHU1
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

1549858:MC45 RS12165
gene id: 1549858:MC45_RS12165
uniprot id: A0A097EHJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1549858:MC45 RS12605
gene id: 1549858:MC45_RS12605
uniprot id: A0A097EHN9
names: Similarity
messages: Belongs to the DapA family.

1549858:MC45 RS03670
gene id: 1549858:MC45_RS03670
uniprot id: A0A097EDN4
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS09875
gene id: 1549858:MC45_RS09875
uniprot id: A0A097EGC8
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS08920
gene id: 1549858:MC45_RS08920
uniprot id: A0A097EFY0
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Monomer.

1549858:MC45 RS00940
gene id: 1549858:MC45_RS00940
uniprot id: A0A097ECD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS03630
gene id: 1549858:MC45_RS03630
uniprot id: A0A097EDI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1549858:MC45 RS12550
gene id: 1549858:MC45_RS12550
uniprot id: A0A097EKW4
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

1549858:MC45 RS13925
gene id: 1549858:MC45_RS13925
uniprot id: A0A097EL07
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1549858:MC45 RS12580
gene id: 1549858:MC45_RS12580
uniprot id: A0A097EHL5
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1549858:MC45 RS09795
gene id: 1549858:MC45_RS09795
uniprot id: A0A097EGC7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1549858:MC45 RS03760
gene id: 1549858:MC45_RS03760
uniprot id: A0A097EDP5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1549858:MC45 RS17430
gene id: 1549858:MC45_RS17430
uniprot id: A0A097EJU2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1549858:MC45 RS01470
gene id: 1549858:MC45_RS01470
uniprot id: A0A097ECK6
names: Similarity
messages: Belongs to the peptidase S33 family.

1549858:MC45 RS04595
gene id: 1549858:MC45_RS04595
uniprot id: A0A097EE26
names: PTM
names: Subcellular Location Annotation
messages: Covalently binds the prosthetic group of malonate decarboxylase.
messages: Cytoplasm

1549858:MC45 RS07860
gene id: 1549858:MC45_RS07860
uniprot id: A0A097EFG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1549858:MC45 RS11610
gene id: 1549858:MC45_RS11610
uniprot id: A0A097EH82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1549858:MC45 RS08690
gene id: 1549858:MC45_RS08690
uniprot id: A0A097EFU0
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

1549858:MC45 RS02425
gene id: 1549858:MC45_RS02425
uniprot id: A0A097ED34
names: Similarity
messages: Belongs to the histone deacetylase family.

1549858:MC45 RS14825
gene id: 1549858:MC45_RS14825
uniprot id: A0A097EIP5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1549858:MC45 RS11775
gene id: 1549858:MC45_RS11775
uniprot id: A0A097EHC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1549858:MC45 RS09790
gene id: 1549858:MC45_RS09790
uniprot id: A0A097EGB6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

1549858:MC45 RS10330
gene id: 1549858:MC45_RS10330
uniprot id: A0A097EGK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS09100
gene id: 1549858:MC45_RS09100
uniprot id: A0A097EFZ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS10170
gene id: 1549858:MC45_RS10170
uniprot id: A0A097EGJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1549858:MC45 RS04145
gene id: 1549858:MC45_RS04145
uniprot id: A0A097EDR6
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS02760
gene id: 1549858:MC45_RS02760
uniprot id: A0A097EK54
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1549858:MC45 RS04055
gene id: 1549858:MC45_RS04055
uniprot id: A0A097EDR8
names: Subcellular Location Annotation
messages: Cell outer membrane

1549858:MC45 RS12480
gene id: 1549858:MC45_RS12480
uniprot id: A0A097EHL6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

1549858:MC45 RS06660
gene id: 1549858:MC45_RS06660
uniprot id: A0A097EF20
names: Similarity
messages: Belongs to the ArsC family.

1549858:MC45 RS14490
gene id: 1549858:MC45_RS14490
uniprot id: A0A097EIK0
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1549858:MC45 RS13235
gene id: 1549858:MC45_RS13235
uniprot id: A0A097EHX1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1549858:MC45 RS08565
gene id: 1549858:MC45_RS08565
uniprot id: A0A097EFR0
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1549858:MC45 RS18350
gene id: 1549858:MC45_RS18350
uniprot id: A0A097ELN6
names: Similarity
messages: Belongs to the MobA/MobL family.

1549858:MC45 RS01770
gene id: 1549858:MC45_RS01770
uniprot id: A0A097ECS6
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1549858:MC45 RS03740
gene id: 1549858:MC45_RS03740
uniprot id: A0A097EDL5
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

1549858:MC45 RS09275
gene id: 1549858:MC45_RS09275
uniprot id: A0A097EG29
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS12890
gene id: 1549858:MC45_RS12890
uniprot id: A0A097EHS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1549858:MC45 RS16255
gene id: 1549858:MC45_RS16255
uniprot id: A0A097EJB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1549858:MC45 RS08490
gene id: 1549858:MC45_RS08490
uniprot id: A0A097EFP8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1549858:MC45 RS02325
gene id: 1549858:MC45_RS02325
uniprot id: A0A097ECY2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1549858:MC45 RS04685
gene id: 1549858:MC45_RS04685
uniprot id: A0A097EE27
names: Similarity
messages: Belongs to the thioredoxin family.

1549858:MC45 RS01555
gene id: 1549858:MC45_RS01555
uniprot id: A0A097ECL7
names: Similarity
messages: Belongs to the peptidase S9C family.

1549858:MC45 RS08370
gene id: 1549858:MC45_RS08370
uniprot id: A0A097EFR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1549858:MC45 RS15635
gene id: 1549858:MC45_RS15635
uniprot id: A0A097EJ24
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

1549858:MC45 RS00540
gene id: 1549858:MC45_RS00540
uniprot id: A0A097EC70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1549858:MC45 RS13785
gene id: 1549858:MC45_RS13785
uniprot id: A0A097EI84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1549858:MC45 RS02345
gene id: 1549858:MC45_RS02345
uniprot id: A0A097ECZ6
names: Function
messages: Multidrug efflux pump.

1549858:MC45 RS11375
gene id: 1549858:MC45_RS11375
uniprot id: A0A097EH46
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

1549858:MC45 RS04910
gene id: 1549858:MC45_RS04910
uniprot id: A0A097EE46
names: Similarity
messages: Belongs to the citrate synthase family.

1549858:MC45 RS03460
gene id: 1549858:MC45_RS03460
uniprot id: A0A097EDI1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1549858:MC45 RS03215
gene id: 1549858:MC45_RS03215
uniprot id: A0A097EDB5
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1549858:MC45 RS02230
gene id: 1549858:MC45_RS02230
uniprot id: A0A097ECY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS13535
gene id: 1549858:MC45_RS13535
uniprot id: A0A097EI22
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS02925
gene id: 1549858:MC45_RS02925
uniprot id: A0A097ED79
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1549858:MC45 RS05935
gene id: 1549858:MC45_RS05935
uniprot id: A0A097EEQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

1549858:MC45 RS05010
gene id: 1549858:MC45_RS05010
uniprot id: A0A097EE86
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1549858:MC45 RS10800
gene id: 1549858:MC45_RS10800
uniprot id: A0A097EGT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1549858:MC45 RS12235
gene id: 1549858:MC45_RS12235
uniprot id: A0A097EHI1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1549858:MC45 RS18140
gene id: 1549858:MC45_RS18140
uniprot id: A0A097ELJ0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1549858:MC45 RS16505
gene id: 1549858:MC45_RS16505
uniprot id: A0A097EJF9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1549858:MC45 RS06685
gene id: 1549858:MC45_RS06685
uniprot id: A0A097EF24
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

1549858:MC45 RS16635
gene id: 1549858:MC45_RS16635
uniprot id: A0A097EL80
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1549858:MC45 RS14635
gene id: 1549858:MC45_RS14635
uniprot id: A0A097EIM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1549858:MC45 RS04895
gene id: 1549858:MC45_RS04895
uniprot id: A0A097EE61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1549858:MC45 RS08635
gene id: 1549858:MC45_RS08635
uniprot id: A0A097EFS6
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1549858:MC45 RS11605
gene id: 1549858:MC45_RS11605
uniprot id: A0A097EH68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1549858:MC45 RS11015
gene id: 1549858:MC45_RS11015
uniprot id: A0A097EGW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1549858:MC45 RS03590
gene id: 1549858:MC45_RS03590
uniprot id: A0A097EDM1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1549858:MC45 RS10595
gene id: 1549858:MC45_RS10595
uniprot id: A0A097EGP8
names: Similarity
messages: Belongs to the BolA/IbaG family.

1549858:MC45 RS13115
gene id: 1549858:MC45_RS13115
uniprot id: A0A097EHV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1549858:MC45 RS17410
gene id: 1549858:MC45_RS17410
uniprot id: A0A097EJT0
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS13995
gene id: 1549858:MC45_RS13995
uniprot id: A0A097EIA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1549858:MC45 RS12255
gene id: 1549858:MC45_RS12255
uniprot id: A0A097EHH5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1549858:MC45 RS09160
gene id: 1549858:MC45_RS09160
uniprot id: A0A097EG25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1549858:MC45 RS05595
gene id: 1549858:MC45_RS05595
uniprot id: A0A097EEG4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1549858:MC45 RS16790
gene id: 1549858:MC45_RS16790
uniprot id: A0A097EL91
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

1549858:MC45 RS03440
gene id: 1549858:MC45_RS03440
uniprot id: A0A097EDG0
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1549858:MC45 RS03530
gene id: 1549858:MC45_RS03530
uniprot id: A0A097EK72
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1549858:MC45 RS02320
gene id: 1549858:MC45_RS02320
uniprot id: A0A097ECX4
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1549858:MC45 RS06570
gene id: 1549858:MC45_RS06570
uniprot id: A0A097EKG4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1549858:MC45 RS12020
gene id: 1549858:MC45_RS12020
uniprot id: A0A097EHE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1549858:MC45 RS17280
gene id: 1549858:MC45_RS17280
uniprot id: A0A097EJS1
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS08410
gene id: 1549858:MC45_RS08410
uniprot id: A0A097EFN4
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

1549858:MC45 RS05290
gene id: 1549858:MC45_RS05290
uniprot id: A0A097EEC6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1549858:MC45 RS12930
gene id: 1549858:MC45_RS12930
uniprot id: A0A097EHS2
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

1549858:MC45 RS02655
gene id: 1549858:MC45_RS02655
uniprot id: A0A097ED70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1549858:MC45 RS08640
gene id: 1549858:MC45_RS08640
uniprot id: A0A097EKL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1549858:MC45 RS12945
gene id: 1549858:MC45_RS12945
uniprot id: A0A097EHT1
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS04545
gene id: 1549858:MC45_RS04545
uniprot id: A0A097EK86
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1549858:MC45 RS03565
gene id: 1549858:MC45_RS03565
uniprot id: A0A097EK66
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1549858:MC45 RS03700
gene id: 1549858:MC45_RS03700
uniprot id: A0A097EDN8
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1549858:MC45 RS19770
gene id: 1549858:MC45_RS19770
uniprot id: A0A097EEP4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1549858:MC45 RS00855
gene id: 1549858:MC45_RS00855
uniprot id: A0A097ECB7
names: Similarity
messages: Belongs to the UPF0246 family.

1549858:MC45 RS00805
gene id: 1549858:MC45_RS00805
uniprot id: A0A097ECB5
names: Similarity
messages: Belongs to the GST superfamily.

1549858:MC45 RS01085
gene id: 1549858:MC45_RS01085
uniprot id: A0A097ECF7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1549858:MC45 RS03180
gene id: 1549858:MC45_RS03180
uniprot id: A0A097EDC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1549858:MC45 RS17245
gene id: 1549858:MC45_RS17245
uniprot id: A0A097ELA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1549858:MC45 RS15990
gene id: 1549858:MC45_RS15990
uniprot id: A0A097EJ86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS16690
gene id: 1549858:MC45_RS16690
uniprot id: A0A097EJJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS03190
gene id: 1549858:MC45_RS03190
uniprot id: A0A097EDB1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1549858:MC45 RS17820
gene id: 1549858:MC45_RS17820
uniprot id: A0A097ELE6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1549858:MC45 RS13005
gene id: 1549858:MC45_RS13005
uniprot id: A0A097EHW1
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1549858:MC45 RS16160
gene id: 1549858:MC45_RS16160
uniprot id: A0A097EJA7
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1549858:MC45 RS16010
gene id: 1549858:MC45_RS16010
uniprot id: A0A097EJ71
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1549858:MC45 RS12325
gene id: 1549858:MC45_RS12325
uniprot id: A0A097EHJ2
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

1549858:MC45 RS06665
gene id: 1549858:MC45_RS06665
uniprot id: A0A097EEX4
names: Function
names: Similarity
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

1549858:MC45 RS15920
gene id: 1549858:MC45_RS15920
uniprot id: A0A097EJ69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS14025
gene id: 1549858:MC45_RS14025
uniprot id: A0A097EIB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

1549858:MC45 RS06245
gene id: 1549858:MC45_RS06245
uniprot id: A0A097EER7
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1549858:MC45 RS09755
gene id: 1549858:MC45_RS09755
uniprot id: A0A097EGB1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1549858:MC45 RS01820
gene id: 1549858:MC45_RS01820
uniprot id: A0A097ECQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1549858:MC45 RS14705
gene id: 1549858:MC45_RS14705
uniprot id: A0A097EIM2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

1549858:MC45 RS12800
gene id: 1549858:MC45_RS12800
uniprot id: A0A097EHT3
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1549858:MC45 RS09085
gene id: 1549858:MC45_RS09085
uniprot id: A0A097EFZ7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1549858:MC45 RS01675
gene id: 1549858:MC45_RS01675
uniprot id: A0A097ECR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1549858:MC45 RS09260
gene id: 1549858:MC45_RS09260
uniprot id: A0A097EG24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1549858:MC45 RS08580
gene id: 1549858:MC45_RS08580
uniprot id: A0A097EFR5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1549858:MC45 RS09005
gene id: 1549858:MC45_RS09005
uniprot id: A0A097EFX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1549858:MC45 RS07810
gene id: 1549858:MC45_RS07810
uniprot id: A0A097EFJ1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1549858:MC45 RS09590
gene id: 1549858:MC45_RS09590
uniprot id: A0A097EG95
names: Similarity
messages: Belongs to the BolA/IbaG family.

1549858:MC45 RS11970
gene id: 1549858:MC45_RS11970
uniprot id: A0A097EHD8
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

1549858:MC45 RS06835
gene id: 1549858:MC45_RS06835
uniprot id: A0A097EF03
names: Similarity
messages: Belongs to the peptidase C56 family.

1549858:MC45 RS17250
gene id: 1549858:MC45_RS17250
uniprot id: A0A097EJS0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS10410
gene id: 1549858:MC45_RS10410
uniprot id: A0A097EGP1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1549858:MC45 RS04345
gene id: 1549858:MC45_RS04345
uniprot id: A0A097EDX3
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1549858:MC45 RS10810
gene id: 1549858:MC45_RS10810
uniprot id: A0A097EGV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1549858:MC45 RS09125
gene id: 1549858:MC45_RS09125
uniprot id: A0A097EG02
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1549858:MC45 RS12065
gene id: 1549858:MC45_RS12065
uniprot id: A0A097EHH3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1549858:MC45 RS08850
gene id: 1549858:MC45_RS08850
uniprot id: A0A097EFW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1549858:MC45 RS05080
gene id: 1549858:MC45_RS05080
uniprot id: A0A097EEB0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS09735
gene id: 1549858:MC45_RS09735
uniprot id: A0A097EGB7
names: Function
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

1549858:MC45 RS17525
gene id: 1549858:MC45_RS17525
uniprot id: A0A097EJV2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1549858:MC45 RS11295
gene id: 1549858:MC45_RS11295
uniprot id: A0A097EH06
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1549858:MC45 RS03620
gene id: 1549858:MC45_RS03620
uniprot id: A0A097EDJ5
names: Similarity
messages: Belongs to the TrpF family.

1549858:MC45 RS07970
gene id: 1549858:MC45_RS07970
uniprot id: A0A097EFI0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1549858:MC45 RS11315
gene id: 1549858:MC45_RS11315
uniprot id: A0A097EH33
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1549858:MC45 RS04195
gene id: 1549858:MC45_RS04195
uniprot id: A0A097EDU2
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1549858:MC45 RS05205
gene id: 1549858:MC45_RS05205
uniprot id: A0A097EEC8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1549858:MC45 RS08365
gene id: 1549858:MC45_RS08365
uniprot id: A0A097EFM8
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1549858:MC45 RS15275
gene id: 1549858:MC45_RS15275
uniprot id: A0A097EIV4
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

1549858:MC45 RS12085
gene id: 1549858:MC45_RS12085
uniprot id: A0A097EHE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1549858:MC45 RS10910
gene id: 1549858:MC45_RS10910
uniprot id: A0A097EGV8
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1549858:MC45 RS17660
gene id: 1549858:MC45_RS17660
uniprot id: A0A097ELL2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1549858:MC45 RS07065
gene id: 1549858:MC45_RS07065
uniprot id: A0A097EF84
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1549858:MC45 RS11600
gene id: 1549858:MC45_RS11600
uniprot id: A0A097EH80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1549858:MC45 RS01565
gene id: 1549858:MC45_RS01565
uniprot id: A0A097ECL4
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1549858:MC45 RS13645
gene id: 1549858:MC45_RS13645
uniprot id: A0A097EI45
names: Similarity
messages: Belongs to the peptidase U62 family.

1549858:MC45 RS01800
gene id: 1549858:MC45_RS01800
uniprot id: A0A097ECT1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1549858:MC45 RS05630
gene id: 1549858:MC45_RS05630
uniprot id: A0A097EEG5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1549858:MC45 RS02830
gene id: 1549858:MC45_RS02830
uniprot id: A0A097EDA2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1549858:MC45 RS05785
gene id: 1549858:MC45_RS05785
uniprot id: A0A097EEJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1549858:MC45 RS11805
gene id: 1549858:MC45_RS11805
uniprot id: A0A097EHA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1549858:MC45 RS14105
gene id: 1549858:MC45_RS14105
uniprot id: A0A097EL18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1549858:MC45 RS12120
gene id: 1549858:MC45_RS12120
uniprot id: A0A097EHG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

1549858:MC45 RS04280
gene id: 1549858:MC45_RS04280
uniprot id: A0A097EDX5
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS07780
gene id: 1549858:MC45_RS07780
uniprot id: A0A097EFI6
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS16335
gene id: 1549858:MC45_RS16335
uniprot id: A0A097EJE0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

1549858:MC45 RS18465
gene id: 1549858:MC45_RS18465
uniprot id: A0A097ELQ8
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS09480
gene id: 1549858:MC45_RS09480
uniprot id: A0A097EG64
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS04310
gene id: 1549858:MC45_RS04310
uniprot id: A0A097EDY1
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1549858:MC45 RS02510
gene id: 1549858:MC45_RS02510
uniprot id: A0A097ED14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1549858:MC45 RS13155
gene id: 1549858:MC45_RS13155
uniprot id: A0A097EHV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

1549858:MC45 RS03000
gene id: 1549858:MC45_RS03000
uniprot id: A0A097ED81
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1549858:MC45 RS08360
gene id: 1549858:MC45_RS08360
uniprot id: A0A097EFM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1549858:MC45 RS05960
gene id: 1549858:MC45_RS05960
uniprot id: A0A097EEL7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1549858:MC45 RS10155
gene id: 1549858:MC45_RS10155
uniprot id: A0A097EGH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1549858:MC45 RS11865
gene id: 1549858:MC45_RS11865
uniprot id: A0A097EHB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1549858:MC45 RS15845
gene id: 1549858:MC45_RS15845
uniprot id: A0A097EJ48
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1549858:MC45 RS10220
gene id: 1549858:MC45_RS10220
uniprot id: A0A097EGI5
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1549858:MC45 RS10250
gene id: 1549858:MC45_RS10250
uniprot id: A0A097EGJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1549858:MC45 RS06655
gene id: 1549858:MC45_RS06655
uniprot id: A0A097EEY2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1549858:MC45 RS02970
gene id: 1549858:MC45_RS02970
uniprot id: A0A097ED83
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1549858:MC45 RS06165
gene id: 1549858:MC45_RS06165
uniprot id: A0A097EER0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1549858:MC45 RS11795
gene id: 1549858:MC45_RS11795
uniprot id: A0A097EHA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1549858:MC45 RS13255
gene id: 1549858:MC45_RS13255
uniprot id: A0A097EHY2
names: Subcellular Location Annotation
messages: Cytoplasm

1549858:MC45 RS04325
gene id: 1549858:MC45_RS04325
uniprot id: A0A097EDU8
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1549858:MC45 RS16675
gene id: 1549858:MC45_RS16675
uniprot id: A0A097EJH7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1549858:MC45 RS10740
gene id: 1549858:MC45_RS10740
uniprot id: A0A097EGR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

1549858:MC45 RS08865
gene id: 1549858:MC45_RS08865
uniprot id: A0A097EFW3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1549858:MC45 RS05715
gene id: 1549858:MC45_RS05715
uniprot id: A0A097EEI0
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1549858:MC45 RS11540
gene id: 1549858:MC45_RS11540
uniprot id: A0A097EH48
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1549858:MC45 RS11335
gene id: 1549858:MC45_RS11335
uniprot id: A0A097EH26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1549858:MC45 RS14615
gene id: 1549858:MC45_RS14615
uniprot id: A0A097EIJ6
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1549858:MC45 RS17750
gene id: 1549858:MC45_RS17750
uniprot id: A0A097ELD4
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1549858:MC45 RS10085
gene id: 1549858:MC45_RS10085
uniprot id: A0A097EGI1
names: Function
names: Similarity
messages: A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex.
messages: Belongs to the bacterial AtpI family.

1549858:MC45 RS01095
gene id: 1549858:MC45_RS01095
uniprot id: A0A097ECI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1549858:MC45 RS17930
gene id: 1549858:MC45_RS17930
uniprot id: A0A097ELF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

1549858:MC45 RS07750
gene id: 1549858:MC45_RS07750
uniprot id: A0A097EFI1
names: Similarity
messages: Belongs to the PhoH family.

1549858:MC45 RS01695
gene id: 1549858:MC45_RS01695
uniprot id: A0A097EK22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS09065
gene id: 1549858:MC45_RS09065
uniprot id: A0A097EFZ0
names: Subunit
messages: Homodimer.

1549858:MC45 RS03170
gene id: 1549858:MC45_RS03170
uniprot id: A0A097EDB7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS11870
gene id: 1549858:MC45_RS11870
uniprot id: A0A097EHB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1549858:MC45 RS13405
gene id: 1549858:MC45_RS13405
uniprot id: A0A097EI07
names: Similarity
messages: Belongs to the AAA ATPase family.

1549858:MC45 RS12520
gene id: 1549858:MC45_RS12520
uniprot id: A0A097EHK8
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1549858:MC45 RS12470
gene id: 1549858:MC45_RS12470
uniprot id: A0A097EHJ8
names: Similarity
messages: Belongs to the MotB family.

1549858:MC45 RS18420
gene id: 1549858:MC45_RS18420
uniprot id: A0A097ELS6
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1549858:MC45 RS14765
gene id: 1549858:MC45_RS14765
uniprot id: A0A097EL36
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1549858:MC45 RS13935
gene id: 1549858:MC45_RS13935
uniprot id: A0A097EI96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.
messages: Membrane

1549858:MC45 RS13290
gene id: 1549858:MC45_RS13290
uniprot id: A0A097EI02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1549858:MC45 RS03295
gene id: 1549858:MC45_RS03295
uniprot id: A0A097EDD8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1549858:MC45 RS05995
gene id: 1549858:MC45_RS05995
uniprot id: A0A097EEN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1549858:MC45 RS03500
gene id: 1549858:MC45_RS03500
uniprot id: A0A097EDI7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1549858:MC45 RS00915
gene id: 1549858:MC45_RS00915
uniprot id: A0A097EJZ6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1549858:MC45 RS08770
gene id: 1549858:MC45_RS08770
uniprot id: A0A097EKN1
names: Subcellular Location Annotation
messages: Cell outer membrane

1549858:MC45 RS07590
gene id: 1549858:MC45_RS07590
uniprot id: A0A097EFB6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1549858:MC45 RS14230
gene id: 1549858:MC45_RS14230
uniprot id: A0A097EIF9
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS10585
gene id: 1549858:MC45_RS10585
uniprot id: A0A097EGP3
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1549858:MC45 RS02090
gene id: 1549858:MC45_RS02090
uniprot id: A0A097ECU2
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1549858:MC45 RS13280
gene id: 1549858:MC45_RS13280
uniprot id: A0A097EHY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1549858:MC45 RS13305
gene id: 1549858:MC45_RS13305
uniprot id: A0A097EHZ2
names: Similarity
messages: Belongs to the type III secretion exporter family.

1549858:MC45 RS17040
gene id: 1549858:MC45_RS17040
uniprot id: A0A097EJM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1549858:MC45 RS05885
gene id: 1549858:MC45_RS05885
uniprot id: A0A097EEK7
names: Similarity
messages: Belongs to the HesB/IscA family.

1549858:MC45 RS11790
gene id: 1549858:MC45_RS11790
uniprot id: A0A097EHA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1549858:MC45 RS03915
gene id: 1549858:MC45_RS03915
uniprot id: A0A097EDP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

1549858:MC45 RS15280
gene id: 1549858:MC45_RS15280
uniprot id: A0A097EIV7
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1549858:MC45 RS05380
gene id: 1549858:MC45_RS05380
uniprot id: A0A097EED9
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

1549858:MC45 RS03160
gene id: 1549858:MC45_RS03160
uniprot id: A0A097EDF9
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS05890
gene id: 1549858:MC45_RS05890
uniprot id: A0A097EEK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

1549858:MC45 RS04615
gene id: 1549858:MC45_RS04615
uniprot id: A0A097EE15
names: Function
names: Similarity
messages: Belongs to the CitG/MdcB family.
messages: Involved in the formation of 2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase.

1549858:MC45 RS03030
gene id: 1549858:MC45_RS03030
uniprot id: A0A097EDD5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1549858:MC45 RS02825
gene id: 1549858:MC45_RS02825
uniprot id: A0A097ED48
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS05170
gene id: 1549858:MC45_RS05170
uniprot id: A0A097EEA9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1549858:MC45 RS10025
gene id: 1549858:MC45_RS10025
uniprot id: A0A097EGE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1549858:MC45 RS02920
gene id: 1549858:MC45_RS02920
uniprot id: A0A097EDB8
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS00215
gene id: 1549858:MC45_RS00215
uniprot id: A0A097EC30
names: Similarity
messages: Belongs to the MobA/MobL family.

1549858:MC45 RS05235
gene id: 1549858:MC45_RS05235
uniprot id: A0A097EEB8
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS04970
gene id: 1549858:MC45_RS04970
uniprot id: A0A097EE73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1549858:MC45 RS01900
gene id: 1549858:MC45_RS01900
uniprot id: A0A097ECU6
names: Function
names: Similarity
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.

1549858:MC45 RS00680
gene id: 1549858:MC45_RS00680
uniprot id: A0A097EC88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1549858:MC45 RS06810
gene id: 1549858:MC45_RS06810
uniprot id: A0A097EF07
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS01815
gene id: 1549858:MC45_RS01815
uniprot id: A0A097ECR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1549858:MC45 RS03035
gene id: 1549858:MC45_RS03035
uniprot id: A0A097EK60
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1549858:MC45 RS09645
gene id: 1549858:MC45_RS09645
uniprot id: A0A097EG93
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1549858:MC45 RS06295
gene id: 1549858:MC45_RS06295
uniprot id: A0A097EEW2
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1549858:MC45 RS10820
gene id: 1549858:MC45_RS10820
uniprot id: A0A097EGT1
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS05895
gene id: 1549858:MC45_RS05895
uniprot id: A0A097EEM2
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS11710
gene id: 1549858:MC45_RS11710
uniprot id: A0A097EH90
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1549858:MC45 RS17050
gene id: 1549858:MC45_RS17050
uniprot id: A0A097EJN6
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS17275
gene id: 1549858:MC45_RS17275
uniprot id: A0A097EJR2
names: Similarity
messages: Belongs to the peptidase M16 family.

1549858:MC45 RS00590
gene id: 1549858:MC45_RS00590
uniprot id: A0A097EC79
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1549858:MC45 RS12425
gene id: 1549858:MC45_RS12425
uniprot id: A0A097EHN1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1549858:MC45 RS04855
gene id: 1549858:MC45_RS04855
uniprot id: A0A097EE56
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family.

1549858:MC45 RS14495
gene id: 1549858:MC45_RS14495
uniprot id: A0A097EIH7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1549858:MC45 RS05720
gene id: 1549858:MC45_RS05720
uniprot id: A0A097EKD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1549858:MC45 RS13860
gene id: 1549858:MC45_RS13860
uniprot id: A0A097EI88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1549858:MC45 RS01515
gene id: 1549858:MC45_RS01515
uniprot id: A0A097ECL1
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1549858:MC45 RS01790
gene id: 1549858:MC45_RS01790
uniprot id: A0A097ECQ6
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1549858:MC45 RS06955
gene id: 1549858:MC45_RS06955
uniprot id: A0A097EF26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OprB family.
messages: Cell outer membrane

1549858:MC45 RS09530
gene id: 1549858:MC45_RS09530
uniprot id: A0A097EKP2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1549858:MC45 RS08445
gene id: 1549858:MC45_RS08445
uniprot id: A0A097EKL2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1549858:MC45 RS18075
gene id: 1549858:MC45_RS18075
uniprot id: A0A097ELM1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1549858:MC45 RS00885
gene id: 1549858:MC45_RS00885
uniprot id: A0A097ECC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1549858:MC45 RS01735
gene id: 1549858:MC45_RS01735
uniprot id: A0A097ECP6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1549858:MC45 RS13270
gene id: 1549858:MC45_RS13270
uniprot id: A0A097EHX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1549858:MC45 RS08765
gene id: 1549858:MC45_RS08765
uniprot id: A0A097EFW5
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS18300
gene id: 1549858:MC45_RS18300
uniprot id: A0A097ELM8
names: Similarity
messages: Belongs to the UPF0166 family.

1549858:MC45 RS17550
gene id: 1549858:MC45_RS17550
uniprot id: A0A097EJV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1549858:MC45 RS09710
gene id: 1549858:MC45_RS09710
uniprot id: A0A097EGA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1549858:MC45 RS15505
gene id: 1549858:MC45_RS15505
uniprot id: A0A097EIZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1549858:MC45 RS11285
gene id: 1549858:MC45_RS11285
uniprot id: A0A097EH15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1549858:MC45 RS08880
gene id: 1549858:MC45_RS08880
uniprot id: A0A097EFX3
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
messages: Catalyzes the dehydration of D-mannonate. Has no detectable activity with a panel of 70 other acid sugars (in vitro).

1549858:MC45 RS11520
gene id: 1549858:MC45_RS11520
uniprot id: A0A097EH69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1549858:MC45 RS17795
gene id: 1549858:MC45_RS17795
uniprot id: A0A097ELG4
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1549858:MC45 RS03855
gene id: 1549858:MC45_RS03855
uniprot id: A0A097EDN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1549858:MC45 RS11950
gene id: 1549858:MC45_RS11950
uniprot id: A0A097EHC3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1549858:MC45 RS02835
gene id: 1549858:MC45_RS02835
uniprot id: A0A097ED66
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS12130
gene id: 1549858:MC45_RS12130
uniprot id: A0A097EHF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1549858:MC45 RS11875
gene id: 1549858:MC45_RS11875
uniprot id: A0A097EHE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1549858:MC45 RS09670
gene id: 1549858:MC45_RS09670
uniprot id: A0A097EGA8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1549858:MC45 RS05605
gene id: 1549858:MC45_RS05605
uniprot id: A0A097EEG6
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

1549858:MC45 RS06370
gene id: 1549858:MC45_RS06370
uniprot id: A0A097EEX3
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS00770
gene id: 1549858:MC45_RS00770
uniprot id: A0A097ECA9
names: Similarity
messages: Belongs to the virb1 family.

1549858:MC45 RS15480
gene id: 1549858:MC45_RS15480
uniprot id: A0A097EIZ2
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1549858:MC45 RS15360
gene id: 1549858:MC45_RS15360
uniprot id: A0A097EIX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

1549858:MC45 RS14060
gene id: 1549858:MC45_RS14060
uniprot id: A0A097EIA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

1549858:MC45 RS11190
gene id: 1549858:MC45_RS11190
uniprot id: A0A097EH16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1549858:MC45 RS10490
gene id: 1549858:MC45_RS10490
uniprot id: A0A097EGM9
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1549858:MC45 RS09290
gene id: 1549858:MC45_RS09290
uniprot id: A0A097EG41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1549858:MC45 RS15960
gene id: 1549858:MC45_RS15960
uniprot id: A0A097EJ75
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1549858:MC45 RS15105
gene id: 1549858:MC45_RS15105
uniprot id: A0A097EIS2
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1549858:MC45 RS07295
gene id: 1549858:MC45_RS07295
uniprot id: A0A097EF78
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. RhamD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the dehydration of L-rhamnonate to 2-keto-3-deoxy-L-rhamnonate (KDR).
messages: Homooctamer; tetramer of dimers.
messages: Reaction proceeds via a syn dehydration.

1549858:MC45 RS00840
gene id: 1549858:MC45_RS00840
uniprot id: A0A097ECC3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1549858:MC45 RS01025
gene id: 1549858:MC45_RS01025
uniprot id: A0A097EK00
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1549858:MC45 RS02210
gene id: 1549858:MC45_RS02210
uniprot id: A0A097ECV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS10920
gene id: 1549858:MC45_RS10920
uniprot id: A0A097EGX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1549858:MC45 RS12005
gene id: 1549858:MC45_RS12005
uniprot id: A0A097EHD7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1549858:MC45 RS00655
gene id: 1549858:MC45_RS00655
uniprot id: A0A097EC83
names: Similarity
messages: Belongs to the DNA photolyase family.

1549858:MC45 RS11325
gene id: 1549858:MC45_RS11325
uniprot id: A0A097EH14
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1549858:MC45 RS15055
gene id: 1549858:MC45_RS15055
uniprot id: A0A097EL46
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1549858:MC45 RS09495
gene id: 1549858:MC45_RS09495
uniprot id: A0A097EG80
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS17110
gene id: 1549858:MC45_RS17110
uniprot id: A0A097EJN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1549858:MC45 RS06800
gene id: 1549858:MC45_RS06800
uniprot id: A0A097EEZ5
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1549858:MC45 RS04890
gene id: 1549858:MC45_RS04890
uniprot id: A0A097EE74
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1549858:MC45 RS04190
gene id: 1549858:MC45_RS04190
uniprot id: A0A097EDW0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1549858:MC45 RS07770
gene id: 1549858:MC45_RS07770
uniprot id: A0A097EFE4
names: Similarity
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.

1549858:MC45 RS16725
gene id: 1549858:MC45_RS16725
uniprot id: A0A097EJJ0
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1549858:MC45 RS13225
gene id: 1549858:MC45_RS13225
uniprot id: A0A097EHX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1549858:MC45 RS17565
gene id: 1549858:MC45_RS17565
uniprot id: A0A097EJW8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1549858:MC45 RS13835
gene id: 1549858:MC45_RS13835
uniprot id: A0A097EI81
names: Subcellular Location Annotation
messages: Cytoplasm

1549858:MC45 RS01860
gene id: 1549858:MC45_RS01860
uniprot id: A0A097EK34
names: Function
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1549858:MC45 RS12710
gene id: 1549858:MC45_RS12710
uniprot id: A0A097EHS0
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1549858:MC45 RS09450
gene id: 1549858:MC45_RS09450
uniprot id: A0A097EG66
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1549858:MC45 RS12135
gene id: 1549858:MC45_RS12135
uniprot id: A0A097EHI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1549858:MC45 RS05200
gene id: 1549858:MC45_RS05200
uniprot id: A0A097EEB4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1549858:MC45 RS02850
gene id: 1549858:MC45_RS02850
uniprot id: A0A097ED55
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1549858:MC45 RS05695
gene id: 1549858:MC45_RS05695
uniprot id: A0A097EEI1
names: Similarity
messages: Belongs to the TPP enzyme family.

1549858:MC45 RS04240
gene id: 1549858:MC45_RS04240
uniprot id: A0A097EDT3
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1549858:MC45 RS11020
gene id: 1549858:MC45_RS11020
uniprot id: A0A097EGW7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

1549858:MC45 RS17645
gene id: 1549858:MC45_RS17645
uniprot id: A0A097ELB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

1549858:MC45 RS04460
gene id: 1549858:MC45_RS04460
uniprot id: A0A097EDZ4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1549858:MC45 RS10610
gene id: 1549858:MC45_RS10610
uniprot id: A0A097EGP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1549858:MC45 RS04395
gene id: 1549858:MC45_RS04395
uniprot id: A0A097EDX8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1549858:MC45 RS01345
gene id: 1549858:MC45_RS01345
uniprot id: A0A097ECI6
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS15125
gene id: 1549858:MC45_RS15125
uniprot id: A0A097EIT7
names: Similarity
messages: Belongs to the peptidase S41A family.

1549858:MC45 RS10200
gene id: 1549858:MC45_RS10200
uniprot id: A0A097EGI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1549858:MC45 RS13375
gene id: 1549858:MC45_RS13375
uniprot id: A0A097EI01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1549858:MC45 RS04260
gene id: 1549858:MC45_RS04260
uniprot id: A0A097EDV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS15490
gene id: 1549858:MC45_RS15490
uniprot id: A0A097EJ16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1549858:MC45 RS18435
gene id: 1549858:MC45_RS18435
uniprot id: A0A097ELQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

1549858:MC45 RS12720
gene id: 1549858:MC45_RS12720
uniprot id: A0A097EHP6
names: Similarity
messages: Belongs to the IlvD/Edd family.

1549858:MC45 RS13565
gene id: 1549858:MC45_RS13565
uniprot id: A0A097EI29
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1549858:MC45 RS12140
gene id: 1549858:MC45_RS12140
uniprot id: A0A097EHF5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS06540
gene id: 1549858:MC45_RS06540
uniprot id: A0A097EEV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1549858:MC45 RS15270
gene id: 1549858:MC45_RS15270
uniprot id: A0A097EIY2
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

1549858:MC45 RS15340
gene id: 1549858:MC45_RS15340
uniprot id: A0A097EIW8
names: Similarity
messages: Belongs to the threonine synthase family.

1549858:MC45 RS02270
gene id: 1549858:MC45_RS02270
uniprot id: A0A097ECY0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS04255
gene id: 1549858:MC45_RS04255
uniprot id: A0A097EDV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1549858:MC45 RS04385
gene id: 1549858:MC45_RS04385
uniprot id: A0A097EDY4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1549858:MC45 RS10125
gene id: 1549858:MC45_RS10125
uniprot id: A0A097EGI7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1549858:MC45 RS09435
gene id: 1549858:MC45_RS09435
uniprot id: A0A097EG55
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1549858:MC45 RS11900
gene id: 1549858:MC45_RS11900
uniprot id: A0A097EHB9
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1549858:MC45 RS16890
gene id: 1549858:MC45_RS16890
uniprot id: A0A097ELC2
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS09960
gene id: 1549858:MC45_RS09960
uniprot id: A0A097EGE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

1549858:MC45 RS04130
gene id: 1549858:MC45_RS04130
uniprot id: A0A097EDV1
names: Similarity
messages: Belongs to the Skp family.

1549858:MC45 RS01650
gene id: 1549858:MC45_RS01650
uniprot id: A0A097ECM5
names: Similarity
messages: Belongs to the GST superfamily.

1549858:MC45 RS01350
gene id: 1549858:MC45_RS01350
uniprot id: A0A097ECL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1549858:MC45 RS04450
gene id: 1549858:MC45_RS04450
uniprot id: A0A097EE06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1549858:MC45 RS03210
gene id: 1549858:MC45_RS03210
uniprot id: A0A097EDB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1549858:MC45 RS02595
gene id: 1549858:MC45_RS02595
uniprot id: A0A097ED30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1549858:MC45 RS13790
gene id: 1549858:MC45_RS13790
uniprot id: A0A097EI60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1549858:MC45 RS04885
gene id: 1549858:MC45_RS04885
uniprot id: A0A097EE59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1549858:MC45 RS06050
gene id: 1549858:MC45_RS06050
uniprot id: A0A097EEN3
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS12035
gene id: 1549858:MC45_RS12035
uniprot id: A0A097EHG9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1549858:MC45 RS14655
gene id: 1549858:MC45_RS14655
uniprot id: A0A097EIM0
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1549858:MC45 RS11670
gene id: 1549858:MC45_RS11670
uniprot id: A0A097EH77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.

1549858:MC45 RS06125
gene id: 1549858:MC45_RS06125
uniprot id: A0A097EEN9
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer.
messages: Secreted

1549858:MC45 RS08980
gene id: 1549858:MC45_RS08980
uniprot id: A0A097EFZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS06340
gene id: 1549858:MC45_RS06340
uniprot id: A0A097EKF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1549858:MC45 RS06230
gene id: 1549858:MC45_RS06230
uniprot id: A0A097EEV2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1549858:MC45 RS13590
gene id: 1549858:MC45_RS13590
uniprot id: A0A097EI34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

1549858:MC45 RS10075
gene id: 1549858:MC45_RS10075
uniprot id: A0A097EGG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1549858:MC45 RS04080
gene id: 1549858:MC45_RS04080
uniprot id: A0A097EDS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1549858:MC45 RS08555
gene id: 1549858:MC45_RS08555
uniprot id: A0A097EFQ8
names: Similarity
messages: Belongs to the barstar family.

1549858:MC45 RS11205
gene id: 1549858:MC45_RS11205
uniprot id: A0A097EH13
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1549858:MC45 RS16150
gene id: 1549858:MC45_RS16150
uniprot id: A0A097EJ98
names: Function
messages: Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A.

1549858:MC45 RS05970
gene id: 1549858:MC45_RS05970
uniprot id: A0A097EER2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1549858:MC45 RS09915
gene id: 1549858:MC45_RS09915
uniprot id: A0A097EGF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

1549858:MC45 RS03975
gene id: 1549858:MC45_RS03975
uniprot id: A0A097EDN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1549858:MC45 RS00970
gene id: 1549858:MC45_RS00970
uniprot id: A0A097EK07
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1549858:MC45 RS17510
gene id: 1549858:MC45_RS17510
uniprot id: A0A097EJV8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1549858:MC45 RS15855
gene id: 1549858:MC45_RS15855
uniprot id: A0A097EJ54
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1549858:MC45 RS13295
gene id: 1549858:MC45_RS13295
uniprot id: A0A097EHY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1549858:MC45 RS16380
gene id: 1549858:MC45_RS16380
uniprot id: A0A097EJD8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1549858:MC45 RS03445
gene id: 1549858:MC45_RS03445
uniprot id: A0A097EDF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1549858:MC45 RS10430
gene id: 1549858:MC45_RS10430
uniprot id: A0A097EGM7
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1549858:MC45 RS06590
gene id: 1549858:MC45_RS06590
uniprot id: A0A097EEW1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

1549858:MC45 RS10725
gene id: 1549858:MC45_RS10725
uniprot id: A0A097EGS0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1549858:MC45 RS02935
gene id: 1549858:MC45_RS02935
uniprot id: A0A097ED78
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1549858:MC45 RS16540
gene id: 1549858:MC45_RS16540
uniprot id: A0A097EJH5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1549858:MC45 RS07980
gene id: 1549858:MC45_RS07980
uniprot id: A0A097EFH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

1549858:MC45 RS07825
gene id: 1549858:MC45_RS07825
uniprot id: A0A097EFF3
names: Similarity
messages: Belongs to the IlvD/Edd family.

1549858:MC45 RS06285
gene id: 1549858:MC45_RS06285
uniprot id: A0A097EES2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1549858:MC45 RS13960
gene id: 1549858:MC45_RS13960
uniprot id: A0A097EIA1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1549858:MC45 RS13540
gene id: 1549858:MC45_RS13540
uniprot id: A0A097EI42
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1549858:MC45 RS15550
gene id: 1549858:MC45_RS15550
uniprot id: A0A097EJ08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1549858:MC45 RS10680
gene id: 1549858:MC45_RS10680
uniprot id: A0A097EGR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1549858:MC45 RS05775
gene id: 1549858:MC45_RS05775
uniprot id: A0A097EEJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1549858:MC45 RS03475
gene id: 1549858:MC45_RS03475
uniprot id: A0A097EDF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1549858:MC45 RS10590
gene id: 1549858:MC45_RS10590
uniprot id: A0A097EGQ5
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1549858:MC45 RS18150
gene id: 1549858:MC45_RS18150
uniprot id: A0A097ELI9
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS06950
gene id: 1549858:MC45_RS06950
uniprot id: A0A097EF18
names: Similarity
messages: Belongs to the FBPase class 2 family.

1549858:MC45 RS17560
gene id: 1549858:MC45_RS17560
uniprot id: A0A097EJW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1549858:MC45 RS15840
gene id: 1549858:MC45_RS15840
uniprot id: A0A097EJ56
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1549858:MC45 RS17620
gene id: 1549858:MC45_RS17620
uniprot id: A0A097ELC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1549858:MC45 RS12225
gene id: 1549858:MC45_RS12225
uniprot id: A0A097EHH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1549858:MC45 RS11165
gene id: 1549858:MC45_RS11165
uniprot id: A0A097EGY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1549858:MC45 RS07625
gene id: 1549858:MC45_RS07625
uniprot id: A0A097EFC1
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS03185
gene id: 1549858:MC45_RS03185
uniprot id: A0A097EDB4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1549858:MC45 RS03515
gene id: 1549858:MC45_RS03515
uniprot id: A0A097EDG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

1549858:MC45 RS05470
gene id: 1549858:MC45_RS05470
uniprot id: A0A097EEE8
names: Similarity
messages: Belongs to the sterol desaturase family.

1549858:MC45 RS06895
gene id: 1549858:MC45_RS06895
uniprot id: A0A097EF13
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1549858:MC45 RS04875
gene id: 1549858:MC45_RS04875
uniprot id: A0A097EE58
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS09120
gene id: 1549858:MC45_RS09120
uniprot id: A0A097EG17
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1549858:MC45 RS04340
gene id: 1549858:MC45_RS04340
uniprot id: A0A097EDW9
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1549858:MC45 RS16495
gene id: 1549858:MC45_RS16495
uniprot id: A0A097EJG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1549858:MC45 RS12510
gene id: 1549858:MC45_RS12510
uniprot id: A0A097EHM1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1549858:MC45 RS11125
gene id: 1549858:MC45_RS11125
uniprot id: A0A097EH08
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1549858:MC45 RS10325
gene id: 1549858:MC45_RS10325
uniprot id: A0A097EGM4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1549858:MC45 RS11305
gene id: 1549858:MC45_RS11305
uniprot id: A0A097EH30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1549858:MC45 RS04300
gene id: 1549858:MC45_RS04300
uniprot id: A0A097EDU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1549858:MC45 RS17035
gene id: 1549858:MC45_RS17035
uniprot id: A0A097EJP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1549858:MC45 RS06850
gene id: 1549858:MC45_RS06850
uniprot id: A0A097EF51
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1549858:MC45 RS16245
gene id: 1549858:MC45_RS16245
uniprot id: A0A097EJD1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1549858:MC45 RS04085
gene id: 1549858:MC45_RS04085
uniprot id: A0A097EDS5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1549858:MC45 RS01400
gene id: 1549858:MC45_RS01400
uniprot id: A0A097ECJ7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1549858:MC45 RS13370
gene id: 1549858:MC45_RS13370
uniprot id: A0A097EHZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1549858:MC45 RS16815
gene id: 1549858:MC45_RS16815
uniprot id: A0A097EL89
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1549858:MC45 RS03965
gene id: 1549858:MC45_RS03965
uniprot id: A0A097EDQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

1549858:MC45 RS04175
gene id: 1549858:MC45_RS04175
uniprot id: A0A097EDS1
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1549858:MC45 RS01945
gene id: 1549858:MC45_RS01945
uniprot id: A0A097ECT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1549858:MC45 RS12615
gene id: 1549858:MC45_RS12615
uniprot id: A0A097EHN3
names: Similarity
messages: Belongs to the peptidase M24B family.

1549858:MC45 RS09205
gene id: 1549858:MC45_RS09205
uniprot id: A0A097EG31
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1549858:MC45 RS16510
gene id: 1549858:MC45_RS16510
uniprot id: A0A097EJG1
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS16850
gene id: 1549858:MC45_RS16850
uniprot id: A0A097EJL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

1549858:MC45 RS16935
gene id: 1549858:MC45_RS16935
uniprot id: A0A097EJL1
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1549858:MC45 RS11700
gene id: 1549858:MC45_RS11700
uniprot id: A0A097EH96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1549858:MC45 RS08025
gene id: 1549858:MC45_RS08025
uniprot id: A0A097EFM4
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1549858:MC45 RS08890
gene id: 1549858:MC45_RS08890
uniprot id: A0A097EFY7
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 67 family.
messages: Homodimer.

1549858:MC45 RS12025
gene id: 1549858:MC45_RS12025
uniprot id: A0A097EHD6
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1549858:MC45 RS17885
gene id: 1549858:MC45_RS17885
uniprot id: A0A097ELF3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1549858:MC45 RS12515
gene id: 1549858:MC45_RS12515
uniprot id: A0A097EHP2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1549858:MC45 RS14480
gene id: 1549858:MC45_RS14480
uniprot id: A0A097EII4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1549858:MC45 RS02775
gene id: 1549858:MC45_RS02775
uniprot id: A0A097ED40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1549858:MC45 RS09850
gene id: 1549858:MC45_RS09850
uniprot id: A0A097EGE2
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1549858:MC45 RS13585
gene id: 1549858:MC45_RS13585
uniprot id: A0A097EI35
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1549858:MC45 RS16290
gene id: 1549858:MC45_RS16290
uniprot id: A0A097EJC1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1549858:MC45 RS07555
gene id: 1549858:MC45_RS07555
uniprot id: A0A097EFB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1549858:MC45 RS05165
gene id: 1549858:MC45_RS05165
uniprot id: A0A097EE87
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1549858:MC45 RS01560
gene id: 1549858:MC45_RS01560
uniprot id: A0A097ECP8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1549858:MC45 RS15500
gene id: 1549858:MC45_RS15500
uniprot id: A0A097EIZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1549858:MC45 RS02150
gene id: 1549858:MC45_RS02150
uniprot id: A0A097ECW3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS07275
gene id: 1549858:MC45_RS07275
uniprot id: A0A097EF72
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1549858:MC45 RS15485
gene id: 1549858:MC45_RS15485
uniprot id: A0A097EJ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1549858:MC45 RS13315
gene id: 1549858:MC45_RS13315
uniprot id: A0A097EI09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1549858:MC45 RS16275
gene id: 1549858:MC45_RS16275
uniprot id: A0A097EJD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1549858:MC45 RS09770
gene id: 1549858:MC45_RS09770
uniprot id: A0A097EGB3
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1549858:MC45 RS05680
gene id: 1549858:MC45_RS05680
uniprot id: A0A097EEH7
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS03775
gene id: 1549858:MC45_RS03775
uniprot id: A0A097EDL3
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

1549858:MC45 RS14845
gene id: 1549858:MC45_RS14845
uniprot id: A0A097EIP3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1549858:MC45 RS17085
gene id: 1549858:MC45_RS17085
uniprot id: A0A097EJN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1549858:MC45 RS06260
gene id: 1549858:MC45_RS06260
uniprot id: A0A097EER1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1549858:MC45 RS02590
gene id: 1549858:MC45_RS02590
uniprot id: A0A097ED63
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1549858:MC45 RS08775
gene id: 1549858:MC45_RS08775
uniprot id: A0A097EFV1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1549858:MC45 RS17575
gene id: 1549858:MC45_RS17575
uniprot id: A0A097EJW0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1549858:MC45 RS00810
gene id: 1549858:MC45_RS00810
uniprot id: A0A097ECB8
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS04860
gene id: 1549858:MC45_RS04860
uniprot id: A0A097EE68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1549858:MC45 RS13875
gene id: 1549858:MC45_RS13875
uniprot id: A0A097EI86
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1549858:MC45 RS16065
gene id: 1549858:MC45_RS16065
uniprot id: A0A097EJ85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS05115
gene id: 1549858:MC45_RS05115
uniprot id: A0A097EEB5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1549858:MC45 RS02770
gene id: 1549858:MC45_RS02770
uniprot id: A0A097ED50
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1549858:MC45 RS03050
gene id: 1549858:MC45_RS03050
uniprot id: A0A097ED97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1549858:MC45 RS00500
gene id: 1549858:MC45_RS00500
uniprot id: A0A097EC66
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS09220
gene id: 1549858:MC45_RS09220
uniprot id: A0A097EG34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1549858:MC45 RS10175
gene id: 1549858:MC45_RS10175
uniprot id: A0A097EGI0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1549858:MC45 RS09185
gene id: 1549858:MC45_RS09185
uniprot id: A0A097EG30
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1549858:MC45 RS13530
gene id: 1549858:MC45_RS13530
uniprot id: A0A097EI25
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS16345
gene id: 1549858:MC45_RS16345
uniprot id: A0A097EJD4
names: Similarity
messages: Belongs to the PhzF family.

1549858:MC45 RS05615
gene id: 1549858:MC45_RS05615
uniprot id: A0A097EEG7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1549858:MC45 RS16395
gene id: 1549858:MC45_RS16395
uniprot id: A0A097EJF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Could be part of an ABC transporter complex.
messages: Membrane

1549858:MC45 RS06535
gene id: 1549858:MC45_RS06535
uniprot id: A0A097EEU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1549858:MC45 RS02155
gene id: 1549858:MC45_RS02155
uniprot id: A0A097ECV2
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1549858:MC45 RS12500
gene id: 1549858:MC45_RS12500
uniprot id: A0A097EHL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1549858:MC45 RS07815
gene id: 1549858:MC45_RS07815
uniprot id: A0A097EFF4
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1549858:MC45 RS17100
gene id: 1549858:MC45_RS17100
uniprot id: A0A097EJP5
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1549858:MC45 RS13240
gene id: 1549858:MC45_RS13240
uniprot id: A0A097EHZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1549858:MC45 RS01750
gene id: 1549858:MC45_RS01750
uniprot id: A0A097ECP0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1549858:MC45 RS03120
gene id: 1549858:MC45_RS03120
uniprot id: A0A097EDA0
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS00620
gene id: 1549858:MC45_RS00620
uniprot id: A0A097ECB2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1549858:MC45 RS09215
gene id: 1549858:MC45_RS09215
uniprot id: A0A097EG18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1549858:MC45 RS02560
gene id: 1549858:MC45_RS02560
uniprot id: A0A097ED22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1549858:MC45 RS05730
gene id: 1549858:MC45_RS05730
uniprot id: A0A097EEM1
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1549858:MC45 RS14595
gene id: 1549858:MC45_RS14595
uniprot id: A0A097EIK7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS10120
gene id: 1549858:MC45_RS10120
uniprot id: A0A097EGH3
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS11160
gene id: 1549858:MC45_RS11160
uniprot id: A0A097EH12
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1549858:MC45 RS02505
gene id: 1549858:MC45_RS02505
uniprot id: A0A097ED13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1549858:MC45 RS16370
gene id: 1549858:MC45_RS16370
uniprot id: A0A097EJF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1549858:MC45 RS08505
gene id: 1549858:MC45_RS08505
uniprot id: A0A097EFQ1
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS07140
gene id: 1549858:MC45_RS07140
uniprot id: A0A097EF48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS04150
gene id: 1549858:MC45_RS04150
uniprot id: A0A097EDU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1549858:MC45 RS14275
gene id: 1549858:MC45_RS14275
uniprot id: A0A097EIF6
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS00550
gene id: 1549858:MC45_RS00550
uniprot id: A0A097EC67
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS09430
gene id: 1549858:MC45_RS09430
uniprot id: A0A097EG53
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1549858:MC45 RS05795
gene id: 1549858:MC45_RS05795
uniprot id: A0A097EEJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1549858:MC45 RS05640
gene id: 1549858:MC45_RS05640
uniprot id: A0A097EEK3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1549858:MC45 RS02815
gene id: 1549858:MC45_RS02815
uniprot id: A0A097ED64
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS03935
gene id: 1549858:MC45_RS03935
uniprot id: A0A097EDQ1
names: Similarity
messages: Belongs to the GSP N family.

1549858:MC45 RS03625
gene id: 1549858:MC45_RS03625
uniprot id: A0A097EDK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1549858:MC45 RS08275
gene id: 1549858:MC45_RS08275
uniprot id: A0A097EFL7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1549858:MC45 RS14770
gene id: 1549858:MC45_RS14770
uniprot id: A0A097EIM4
names: Similarity
messages: Belongs to the lycopene cyclase family.

1549858:MC45 RS11840
gene id: 1549858:MC45_RS11840
uniprot id: A0A097EHB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1549858:MC45 RS15450
gene id: 1549858:MC45_RS15450
uniprot id: A0A097EIY6
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1549858:MC45 RS03205
gene id: 1549858:MC45_RS03205
uniprot id: A0A097EDD4
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1549858:MC45 RS08130
gene id: 1549858:MC45_RS08130
uniprot id: A0A097EFK6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1549858:MC45 RS05105
gene id: 1549858:MC45_RS05105
uniprot id: A0A097EE99
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1549858:MC45 RS06175
gene id: 1549858:MC45_RS06175
uniprot id: A0A097EEQ0
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

1549858:MC45 RS05665
gene id: 1549858:MC45_RS05665
uniprot id: A0A097EEK8
names: Similarity
messages: Belongs to the bacterial secretin family.

1549858:MC45 RS00615
gene id: 1549858:MC45_RS00615
uniprot id: A0A097EC81
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1549858:MC45 RS03085
gene id: 1549858:MC45_RS03085
uniprot id: A0A097ED95
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1549858:MC45 RS01855
gene id: 1549858:MC45_RS01855
uniprot id: A0A097ECU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1549858:MC45 RS18470
gene id: 1549858:MC45_RS18470
uniprot id: A0A097ELQ6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1549858:MC45 RS06640
gene id: 1549858:MC45_RS06640
uniprot id: A0A097EEX1
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1549858:MC45 RS02460
gene id: 1549858:MC45_RS02460
uniprot id: A0A097ED41
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS15230
gene id: 1549858:MC45_RS15230
uniprot id: A0A097EIU6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1549858:MC45 RS03615
gene id: 1549858:MC45_RS03615
uniprot id: A0A097EDM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1549858:MC45 RS01655
gene id: 1549858:MC45_RS01655
uniprot id: A0A097ECM4
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1549858:MC45 RS02390
gene id: 1549858:MC45_RS02390
uniprot id: A0A097ECZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1549858:MC45 RS09990
gene id: 1549858:MC45_RS09990
uniprot id: A0A097EGE7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1549858:MC45 RS06550
gene id: 1549858:MC45_RS06550
uniprot id: A0A097EF00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1549858:MC45 RS05020
gene id: 1549858:MC45_RS05020
uniprot id: A0A097EE83
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1549858:MC45 RS06530
gene id: 1549858:MC45_RS06530
uniprot id: A0A097EEV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1549858:MC45 RS06320
gene id: 1549858:MC45_RS06320
uniprot id: A0A097EES8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cell inner membrane
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1549858:MC45 RS11855
gene id: 1549858:MC45_RS11855
uniprot id: A0A097EHB2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1549858:MC45 RS07610
gene id: 1549858:MC45_RS07610
uniprot id: A0A097EFG0
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1549858:MC45 RS11785
gene id: 1549858:MC45_RS11785
uniprot id: A0A097EHA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1549858:MC45 RS03075
gene id: 1549858:MC45_RS03075
uniprot id: A0A097EDB6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1549858:MC45 RS16680
gene id: 1549858:MC45_RS16680
uniprot id: A0A097EJI5
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1549858:MC45 RS04730
gene id: 1549858:MC45_RS04730
uniprot id: A0A097EE35
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1549858:MC45 RS17045
gene id: 1549858:MC45_RS17045
uniprot id: A0A097EJM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1549858:MC45 RS14560
gene id: 1549858:MC45_RS14560
uniprot id: A0A097EII7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1549858:MC45 RS04960
gene id: 1549858:MC45_RS04960
uniprot id: A0A097EE53
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS17370
gene id: 1549858:MC45_RS17370
uniprot id: A0A097EJS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS00910
gene id: 1549858:MC45_RS00910
uniprot id: A0A097ECG0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1549858:MC45 RS11780
gene id: 1549858:MC45_RS11780
uniprot id: A0A097EHA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1549858:MC45 RS05055
gene id: 1549858:MC45_RS05055
uniprot id: A0A097EEA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1549858:MC45 RS05880
gene id: 1549858:MC45_RS05880
uniprot id: A0A097EEK9
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1549858:MC45 RS02575
gene id: 1549858:MC45_RS02575
uniprot id: A0A097ED24
names: Similarity
messages: Belongs to the GST superfamily.

1549858:MC45 RS08055
gene id: 1549858:MC45_RS08055
uniprot id: A0A097EFN0
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1549858:MC45 RS12670
gene id: 1549858:MC45_RS12670
uniprot id: A0A097EHP9
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

1549858:MC45 RS12760
gene id: 1549858:MC45_RS12760
uniprot id: A0A097EHQ7
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1549858:MC45 RS01810
gene id: 1549858:MC45_RS01810
uniprot id: A0A097ECP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1549858:MC45 RS08100
gene id: 1549858:MC45_RS08100
uniprot id: A0A097EFJ8
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1549858:MC45 RS10980
gene id: 1549858:MC45_RS10980
uniprot id: A0A097EGV6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1549858:MC45 RS08995
gene id: 1549858:MC45_RS08995
uniprot id: A0A097EFX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S49 family.
messages: Cell inner membrane

1549858:MC45 RS04505
gene id: 1549858:MC45_RS04505
uniprot id: A0A097EDZ3
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1549858:MC45 RS13620
gene id: 1549858:MC45_RS13620
uniprot id: A0A097EI57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1549858:MC45 RS03230
gene id: 1549858:MC45_RS03230
uniprot id: A0A097EDD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS11965
gene id: 1549858:MC45_RS11965
uniprot id: A0A097EHC4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS03925
gene id: 1549858:MC45_RS03925
uniprot id: A0A097EDP6
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1549858:MC45 RS14605
gene id: 1549858:MC45_RS14605
uniprot id: A0A097EIL0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1549858:MC45 RS13525
gene id: 1549858:MC45_RS13525
uniprot id: A0A097EI26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1549858:MC45 RS11495
gene id: 1549858:MC45_RS11495
uniprot id: A0A097EH42
names: Cofactor
messages: Can also use Mn(2+) ion.

1549858:MC45 RS07765
gene id: 1549858:MC45_RS07765
uniprot id: A0A097EFE1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1549858:MC45 RS15310
gene id: 1549858:MC45_RS15310
uniprot id: A0A097EIW3
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1549858:MC45 RS12900
gene id: 1549858:MC45_RS12900
uniprot id: A0A097EHU8
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS04905
gene id: 1549858:MC45_RS04905
uniprot id: A0A097EE62
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1549858:MC45 RS06610
gene id: 1549858:MC45_RS06610
uniprot id: A0A097EF11
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1549858:MC45 RS11045
gene id: 1549858:MC45_RS11045
uniprot id: A0A097EGW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1549858:MC45 RS04470
gene id: 1549858:MC45_RS04470
uniprot id: A0A097EDZ5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS17360
gene id: 1549858:MC45_RS17360
uniprot id: A0A097EJS4
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS17835
gene id: 1549858:MC45_RS17835
uniprot id: A0A097ELG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS14690
gene id: 1549858:MC45_RS14690
uniprot id: A0A097EIN2
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1549858:MC45 RS10795
gene id: 1549858:MC45_RS10795
uniprot id: A0A097EGS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1549858:MC45 RS13685
gene id: 1549858:MC45_RS13685
uniprot id: A0A097EI54
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1549858:MC45 RS13200
gene id: 1549858:MC45_RS13200
uniprot id: A0A097EHW9
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1549858:MC45 RS15045
gene id: 1549858:MC45_RS15045
uniprot id: A0A097EIR5
names: Similarity
messages: Belongs to the peptidase M24B family.

1549858:MC45 RS08060
gene id: 1549858:MC45_RS08060
uniprot id: A0A097EFJ4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1549858:MC45 RS03020
gene id: 1549858:MC45_RS03020
uniprot id: A0A097ED92
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1549858:MC45 RS05180
gene id: 1549858:MC45_RS05180
uniprot id: A0A097EEA8
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1549858:MC45 RS11585
gene id: 1549858:MC45_RS11585
uniprot id: A0A097EH79
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS12845
gene id: 1549858:MC45_RS12845
uniprot id: A0A097EHT8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1549858:MC45 RS14995
gene id: 1549858:MC45_RS14995
uniprot id: A0A097EIU4
names: Similarity
messages: Belongs to the UPF0162 family.

1549858:MC45 RS06675
gene id: 1549858:MC45_RS06675
uniprot id: A0A097EEY1
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1549858:MC45 RS02420
gene id: 1549858:MC45_RS02420
uniprot id: A0A097ECZ7
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1549858:MC45 RS12935
gene id: 1549858:MC45_RS12935
uniprot id: A0A097EHT6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1549858:MC45 RS13830
gene id: 1549858:MC45_RS13830
uniprot id: A0A097EI83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1549858:MC45 RS04880
gene id: 1549858:MC45_RS04880
uniprot id: A0A097EE40
names: Similarity
messages: Belongs to the TrpC family.

1549858:MC45 RS05800
gene id: 1549858:MC45_RS05800
uniprot id: A0A097EEK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1549858:MC45 RS10435
gene id: 1549858:MC45_RS10435
uniprot id: A0A097EGP7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

1549858:MC45 RS14670
gene id: 1549858:MC45_RS14670
uniprot id: A0A097EIM1
names: Similarity
messages: Belongs to the SCO1/2 family.

1549858:MC45 RS01525
gene id: 1549858:MC45_RS01525
uniprot id: A0A097ECK9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1549858:MC45 RS15115
gene id: 1549858:MC45_RS15115
uniprot id: A0A097EIS5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1549858:MC45 RS12535
gene id: 1549858:MC45_RS12535
uniprot id: A0A097EHM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1549858:MC45 RS05175
gene id: 1549858:MC45_RS05175
uniprot id: A0A097EEC4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1549858:MC45 RS05040
gene id: 1549858:MC45_RS05040
uniprot id: A0A097EKB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1549858:MC45 RS04025
gene id: 1549858:MC45_RS04025
uniprot id: A0A097EDR2
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

1549858:MC45 RS03280
gene id: 1549858:MC45_RS03280
uniprot id: A0A097EDD7
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).

1549858:MC45 RS06475
gene id: 1549858:MC45_RS06475
uniprot id: A0A097EEU4
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1549858:MC45 RS13600
gene id: 1549858:MC45_RS13600
uniprot id: A0A097EI27
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1549858:MC45 RS08045
gene id: 1549858:MC45_RS08045
uniprot id: A0A097EFJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell.

1549858:MC45 RS06555
gene id: 1549858:MC45_RS06555
uniprot id: A0A097EEV6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1549858:MC45 RS03330
gene id: 1549858:MC45_RS03330
uniprot id: A0A097EDD6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS13570
gene id: 1549858:MC45_RS13570
uniprot id: A0A097EI47
names: Similarity
messages: Belongs to the sterol desaturase family.

1549858:MC45 RS11835
gene id: 1549858:MC45_RS11835
uniprot id: A0A097EHB5
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1549858:MC45 RS14265
gene id: 1549858:MC45_RS14265
uniprot id: A0A097EIG4
names: Similarity
messages: Belongs to the FeoA family.

1549858:MC45 RS03415
gene id: 1549858:MC45_RS03415
uniprot id: A0A097EDF5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

1549858:MC45 RS14530
gene id: 1549858:MC45_RS14530
uniprot id: A0A097EIJ4
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1549858:MC45 RS02735
gene id: 1549858:MC45_RS02735
uniprot id: A0A097ED47
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

1549858:MC45 RS06870
gene id: 1549858:MC45_RS06870
uniprot id: A0A097EF15
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1549858:MC45 RS10215
gene id: 1549858:MC45_RS10215
uniprot id: A0A097EGI9
names: Similarity
messages: Belongs to the UPF0102 family.

1549858:MC45 RS15180
gene id: 1549858:MC45_RS15180
uniprot id: A0A097EIW5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1549858:MC45 RS07485
gene id: 1549858:MC45_RS07485
uniprot id: A0A097EFE2
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS00520
gene id: 1549858:MC45_RS00520
uniprot id: A0A097EC63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1549858:MC45 RS11845
gene id: 1549858:MC45_RS11845
uniprot id: A0A097EHB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1549858:MC45 RS11895
gene id: 1549858:MC45_RS11895
uniprot id: A0A097EHC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1549858:MC45 RS16015
gene id: 1549858:MC45_RS16015
uniprot id: A0A097EJ84
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1549858:MC45 RS14970
gene id: 1549858:MC45_RS14970
uniprot id: A0A097EIR7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1549858:MC45 RS09105
gene id: 1549858:MC45_RS09105
uniprot id: A0A097EFZ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1549858:MC45 RS14460
gene id: 1549858:MC45_RS14460
uniprot id: A0A097EL28
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1549858:MC45 RS17380
gene id: 1549858:MC45_RS17380
uniprot id: A0A097EJT7
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1549858:MC45 RS08395
gene id: 1549858:MC45_RS08395
uniprot id: A0A097EFR8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1549858:MC45 RS06095
gene id: 1549858:MC45_RS06095
uniprot id: A0A097EEP3
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1549858:MC45 RS12525
gene id: 1549858:MC45_RS12525
uniprot id: A0A097EHM2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1549858:MC45 RS05150
gene id: 1549858:MC45_RS05150
uniprot id: A0A097EEC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1549858:MC45 RS04775
gene id: 1549858:MC45_RS04775
uniprot id: A0A097EE37
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS13625
gene id: 1549858:MC45_RS13625
uniprot id: A0A097EI32
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

1549858:MC45 RS04120
gene id: 1549858:MC45_RS04120
uniprot id: A0A097EDR3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

1549858:MC45 RS15100
gene id: 1549858:MC45_RS15100
uniprot id: A0A097EIV8
names: Similarity
messages: Belongs to the RelE toxin family.

1549858:MC45 RS13665
gene id: 1549858:MC45_RS13665
uniprot id: A0A097EI49
names: Similarity
messages: Belongs to the TPP enzyme family.

1549858:MC45 RS17240
gene id: 1549858:MC45_RS17240
uniprot id: A0A097EJR6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1549858:MC45 RS18110
gene id: 1549858:MC45_RS18110
uniprot id: A0A097ELI1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1549858:MC45 RS13380
gene id: 1549858:MC45_RS13380
uniprot id: A0A097EI03
names: Function
names: Subcellular Location Annotation
messages: Could be a virulence factor.
messages: Secreted

1549858:MC45 RS00165
gene id: 1549858:MC45_RS00165
uniprot id: A0A097EC55
names: Similarity
messages: Belongs to the universal stress protein A family.

1549858:MC45 RS06735
gene id: 1549858:MC45_RS06735
uniprot id: A0A097EEZ0
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS11765
gene id: 1549858:MC45_RS11765
uniprot id: A0A097EH97
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1549858:MC45 RS11720
gene id: 1549858:MC45_RS11720
uniprot id: A0A097EH92
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1549858:MC45 RS13030
gene id: 1549858:MC45_RS13030
uniprot id: A0A097EHU5
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1549858:MC45 RS11385
gene id: 1549858:MC45_RS11385
uniprot id: A0A097EKU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1549858:MC45 RS07665
gene id: 1549858:MC45_RS07665
uniprot id: A0A097EFD5
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1549858:MC45 RS08255
gene id: 1549858:MC45_RS08255
uniprot id: A0A097EFL8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1549858:MC45 RS07985
gene id: 1549858:MC45_RS07985
uniprot id: A0A097EFH8
names: Similarity
messages: Belongs to the Dps family.

1549858:MC45 RS15345
gene id: 1549858:MC45_RS15345
uniprot id: A0A097EIX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1549858:MC45 RS05655
gene id: 1549858:MC45_RS05655
uniprot id: A0A097EEH2
names: Similarity
messages: Belongs to the peptidase A24 family.

1549858:MC45 RS02660
gene id: 1549858:MC45_RS02660
uniprot id: A0A097ED39
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1549858:MC45 RS03680
gene id: 1549858:MC45_RS03680
uniprot id: A0A097EDL8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1549858:MC45 RS06965
gene id: 1549858:MC45_RS06965
uniprot id: A0A097EF70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1549858:MC45 RS10270
gene id: 1549858:MC45_RS10270
uniprot id: A0A097EGJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1549858:MC45 RS04305
gene id: 1549858:MC45_RS04305
uniprot id: A0A097EDW8
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS06115
gene id: 1549858:MC45_RS06115
uniprot id: A0A097EET2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS10745
gene id: 1549858:MC45_RS10745
uniprot id: A0A097EGS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1549858:MC45 RS08715
gene id: 1549858:MC45_RS08715
uniprot id: A0A097EFU7
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1549858:MC45 RS06940
gene id: 1549858:MC45_RS06940
uniprot id: A0A097EF22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1549858:MC45 RS06985
gene id: 1549858:MC45_RS06985
uniprot id: A0A097EF31
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1549858:MC45 RS15590
gene id: 1549858:MC45_RS15590
uniprot id: A0A097EJ34
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS04365
gene id: 1549858:MC45_RS04365
uniprot id: A0A097EDZ1
names: Similarity
messages: Belongs to the fabD family.

1549858:MC45 RS07195
gene id: 1549858:MC45_RS07195
uniprot id: A0A097EFA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS07025
gene id: 1549858:MC45_RS07025
uniprot id: A0A097EF37
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1549858:MC45 RS12050
gene id: 1549858:MC45_RS12050
uniprot id: A0A097EHE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1549858:MC45 RS04405
gene id: 1549858:MC45_RS04405
uniprot id: A0A097EDW2
names: Similarity
messages: Belongs to the MreC family.

1549858:MC45 RS04225
gene id: 1549858:MC45_RS04225
uniprot id: A0A097EDW5
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1549858:MC45 RS11850
gene id: 1549858:MC45_RS11850
uniprot id: A0A097EHD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1549858:MC45 RS06085
gene id: 1549858:MC45_RS06085
uniprot id: A0A097EEN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1549858:MC45 RS16260
gene id: 1549858:MC45_RS16260
uniprot id: A0A097EJC3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1549858:MC45 RS10780
gene id: 1549858:MC45_RS10780
uniprot id: A0A097EGT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1549858:MC45 RS13185
gene id: 1549858:MC45_RS13185
uniprot id: A0A097EHW2
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1549858:MC45 RS11115
gene id: 1549858:MC45_RS11115
uniprot id: A0A097EGZ5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1549858:MC45 RS15160
gene id: 1549858:MC45_RS15160
uniprot id: A0A097EIT2
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1549858:MC45 RS04095
gene id: 1549858:MC45_RS04095
uniprot id: A0A097EDQ8
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1549858:MC45 RS16710
gene id: 1549858:MC45_RS16710
uniprot id: A0A097EJI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS17515
gene id: 1549858:MC45_RS17515
uniprot id: A0A097EJW5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1549858:MC45 RS11860
gene id: 1549858:MC45_RS11860
uniprot id: A0A097EHC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1549858:MC45 RS07645
gene id: 1549858:MC45_RS07645
uniprot id: A0A097EFG6
names: Similarity
messages: Belongs to the HesB/IscA family.

1549858:MC45 RS13410
gene id: 1549858:MC45_RS13410
uniprot id: A0A097EHZ9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1549858:MC45 RS12115
gene id: 1549858:MC45_RS12115
uniprot id: A0A097EHF0
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS02580
gene id: 1549858:MC45_RS02580
uniprot id: A0A097ED20
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

1549858:MC45 RS02615
gene id: 1549858:MC45_RS02615
uniprot id: A0A097ED25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS05585
gene id: 1549858:MC45_RS05585
uniprot id: A0A097EEG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1549858:MC45 RS01880
gene id: 1549858:MC45_RS01880
uniprot id: A0A097ECQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS02765
gene id: 1549858:MC45_RS02765
uniprot id: A0A097ED54
names: Similarity
messages: Belongs to the virb1 family.

1549858:MC45 RS07280
gene id: 1549858:MC45_RS07280
uniprot id: A0A097EF68
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1549858:MC45 RS12715
gene id: 1549858:MC45_RS12715
uniprot id: A0A097EHM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1549858:MC45 RS12450
gene id: 1549858:MC45_RS12450
uniprot id: A0A097EHK6
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1549858:MC45 RS13475
gene id: 1549858:MC45_RS13475
uniprot id: A0A097EI33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1549858:MC45 RS06120
gene id: 1549858:MC45_RS06120
uniprot id: A0A097EEP2
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1549858:MC45 RS09805
gene id: 1549858:MC45_RS09805
uniprot id: A0A097EGB8
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1549858:MC45 RS12060
gene id: 1549858:MC45_RS12060
uniprot id: A0A097EHE7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1549858:MC45 RS04995
gene id: 1549858:MC45_RS04995
uniprot id: A0A097EE78
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1549858:MC45 RS02160
gene id: 1549858:MC45_RS02160
uniprot id: A0A097ECX9
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1549858:MC45 RS09440
gene id: 1549858:MC45_RS09440
uniprot id: A0A097EG71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

1549858:MC45 RS05060
gene id: 1549858:MC45_RS05060
uniprot id: A0A097EE90
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1549858:MC45 RS06930
gene id: 1549858:MC45_RS06930
uniprot id: A0A097EF25
names: Function
names: Similarity
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: May be required for disulfide bond formation in some proteins.

1549858:MC45 RS14890
gene id: 1549858:MC45_RS14890
uniprot id: A0A097EL41
names: Subunit
messages: Homotetramer.

1549858:MC45 RS04975
gene id: 1549858:MC45_RS04975
uniprot id: A0A097EE88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1549858:MC45 RS03755
gene id: 1549858:MC45_RS03755
uniprot id: A0A097EDK5
names: Similarity
messages: Belongs to the asparagine synthetase family.

1549858:MC45 RS17200
gene id: 1549858:MC45_RS17200
uniprot id: A0A097EJQ1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1549858:MC45 RS05535
gene id: 1549858:MC45_RS05535
uniprot id: A0A097EEF6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1549858:MC45 RS08660
gene id: 1549858:MC45_RS08660
uniprot id: A0A097EFT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1549858:MC45 RS01840
gene id: 1549858:MC45_RS01840
uniprot id: A0A097ECR9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1549858:MC45 RS00715
gene id: 1549858:MC45_RS00715
uniprot id: A0A097ECA3
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

1549858:MC45 RS02340
gene id: 1549858:MC45_RS02340
uniprot id: A0A097ECY5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1549858:MC45 RS14420
gene id: 1549858:MC45_RS14420
uniprot id: A0A097EL27
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1549858:MC45 RS02290
gene id: 1549858:MC45_RS02290
uniprot id: A0A097ECX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1549858:MC45 RS13210
gene id: 1549858:MC45_RS13210
uniprot id: A0A097EHW7
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

1549858:MC45 RS09475
gene id: 1549858:MC45_RS09475
uniprot id: A0A097EG72
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS10005
gene id: 1549858:MC45_RS10005
uniprot id: A0A097EGE5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1549858:MC45 RS08625
gene id: 1549858:MC45_RS08625
uniprot id: A0A097EFT7
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1549858:MC45 RS15215
gene id: 1549858:MC45_RS15215
uniprot id: A0A097EIU0
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

1549858:MC45 RS11515
gene id: 1549858:MC45_RS11515
uniprot id: A0A097EH53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

1549858:MC45 RS11170
gene id: 1549858:MC45_RS11170
uniprot id: A0A097EGZ0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-56 and Arg-59) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1549858:MC45 RS16685
gene id: 1549858:MC45_RS16685
uniprot id: A0A097EJI7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1549858:MC45 RS04420
gene id: 1549858:MC45_RS04420
uniprot id: A0A097EE01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1549858:MC45 RS16515
gene id: 1549858:MC45_RS16515
uniprot id: A0A097EJG6
names: Function
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons.

1549858:MC45 RS15395
gene id: 1549858:MC45_RS15395
uniprot id: A0A097EL50
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS13275
gene id: 1549858:MC45_RS13275
uniprot id: A0A097EHY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1549858:MC45 RS09665
gene id: 1549858:MC45_RS09665
uniprot id: A0A097EG92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1549858:MC45 RS16860
gene id: 1549858:MC45_RS16860
uniprot id: A0A097EJK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS00135
gene id: 1549858:MC45_RS00135
uniprot id: A0A097EC29
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1549858:MC45 RS10695
gene id: 1549858:MC45_RS10695
uniprot id: A0A097EGT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

1549858:MC45 RS14870
gene id: 1549858:MC45_RS14870
uniprot id: A0A097EIQ0
names: Similarity
messages: Belongs to the peptidase M1 family.

1549858:MC45 RS07240
gene id: 1549858:MC45_RS07240
uniprot id: A0A097EF63
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1549858:MC45 RS18440
gene id: 1549858:MC45_RS18440
uniprot id: A0A097ELQ1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1549858:MC45 RS12870
gene id: 1549858:MC45_RS12870
uniprot id: A0A097EHR6
names: Similarity
messages: Belongs to the HIBADH-related family.

1549858:MC45 RS17570
gene id: 1549858:MC45_RS17570
uniprot id: A0A097EJX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1549858:MC45 RS04735
gene id: 1549858:MC45_RS04735
uniprot id: A0A097EE51
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

1549858:MC45 RS00450
gene id: 1549858:MC45_RS00450
uniprot id: A0A097EC60
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1549858:MC45 RS02105
gene id: 1549858:MC45_RS02105
uniprot id: A0A097ECU4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1549858:MC45 RS13675
gene id: 1549858:MC45_RS13675
uniprot id: A0A097EI65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1549858:MC45 RS10080
gene id: 1549858:MC45_RS10080
uniprot id: A0A097EGF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1549858:MC45 RS15565
gene id: 1549858:MC45_RS15565
uniprot id: A0A097EJ29
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1549858:MC45 RS02205
gene id: 1549858:MC45_RS02205
uniprot id: A0A097ECY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1549858:MC45 RS11815
gene id: 1549858:MC45_RS11815
uniprot id: A0A097EHA6
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1549858:MC45 RS13330
gene id: 1549858:MC45_RS13330
uniprot id: A0A097EHZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1549858:MC45 RS12575
gene id: 1549858:MC45_RS12575
uniprot id: A0A097EHQ4
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1549858:MC45 RS14300
gene id: 1549858:MC45_RS14300
uniprot id: A0A097EL22
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1549858:MC45 RS13775
gene id: 1549858:MC45_RS13775
uniprot id: A0A097EI72
names: Similarity
messages: Belongs to the YggT family.

1549858:MC45 RS06255
gene id: 1549858:MC45_RS06255
uniprot id: A0A097EEV8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1549858:MC45 RS15525
gene id: 1549858:MC45_RS15525
uniprot id: A0A097EJ03
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1549858:MC45 RS13320
gene id: 1549858:MC45_RS13320
uniprot id: A0A097EHY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1549858:MC45 RS08135
gene id: 1549858:MC45_RS08135
uniprot id: A0A097EFK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS17215
gene id: 1549858:MC45_RS17215
uniprot id: A0A097EJR5
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

1549858:MC45 RS08455
gene id: 1549858:MC45_RS08455
uniprot id: A0A097EFP6
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1549858:MC45 RS15570
gene id: 1549858:MC45_RS15570
uniprot id: A0A097EJ19
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1549858:MC45 RS00710
gene id: 1549858:MC45_RS00710
uniprot id: A0A097EC99
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1549858:MC45 RS01190
gene id: 1549858:MC45_RS01190
uniprot id: A0A097ECG4
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS12465
gene id: 1549858:MC45_RS12465
uniprot id: A0A097EHN6
names: Similarity
messages: Belongs to the ros/MucR family.

1549858:MC45 RS08495
gene id: 1549858:MC45_RS08495
uniprot id: A0A097EFQ0
names: Similarity
messages: Belongs to the peptidase M1 family.

1549858:MC45 RS10020
gene id: 1549858:MC45_RS10020
uniprot id: A0A097EGG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

1549858:MC45 RS17530
gene id: 1549858:MC45_RS17530
uniprot id: A0A097EJW4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1549858:MC45 RS03640
gene id: 1549858:MC45_RS03640
uniprot id: A0A097EDM8
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

1549858:MC45 RS04285
gene id: 1549858:MC45_RS04285
uniprot id: A0A097EDV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1549858:MC45 RS10190
gene id: 1549858:MC45_RS10190
uniprot id: A0A097EGH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1549858:MC45 RS10060
gene id: 1549858:MC45_RS10060
uniprot id: A0A097EGH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1549858:MC45 RS08450
gene id: 1549858:MC45_RS08450
uniprot id: A0A097EFS8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1549858:MC45 RS05610
gene id: 1549858:MC45_RS05610
uniprot id: A0A097EKC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1549858:MC45 RS10445
gene id: 1549858:MC45_RS10445
uniprot id: A0A097EGM5
names: Similarity
messages: Belongs to the LOG family.

1549858:MC45 RS12840
gene id: 1549858:MC45_RS12840
uniprot id: A0A097EL09
names: Similarity
messages: Belongs to the DprA/Smf family.

1549858:MC45 RS12055
gene id: 1549858:MC45_RS12055
uniprot id: A0A097EKV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1549858:MC45 RS05520
gene id: 1549858:MC45_RS05520
uniprot id: A0A097EEF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1549858:MC45 RS08535
gene id: 1549858:MC45_RS08535
uniprot id: A0A097EFT4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1549858:MC45 RS09390
gene id: 1549858:MC45_RS09390
uniprot id: A0A097EG46
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1549858:MC45 RS13970
gene id: 1549858:MC45_RS13970
uniprot id: A0A097EIB7
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1549858:MC45 RS10260
gene id: 1549858:MC45_RS10260
uniprot id: A0A097EGJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1549858:MC45 RS10420
gene id: 1549858:MC45_RS10420
uniprot id: A0A097EGM2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1549858:MC45 RS01795
gene id: 1549858:MC45_RS01795
uniprot id: A0A097ECQ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1549858:MC45 RS13895
gene id: 1549858:MC45_RS13895
uniprot id: A0A097EI93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1549858:MC45 RS12595
gene id: 1549858:MC45_RS12595
uniprot id: A0A097EKW2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS06335
gene id: 1549858:MC45_RS06335
uniprot id: A0A097EEW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1549858:MC45 RS10900
gene id: 1549858:MC45_RS10900
uniprot id: A0A097EGU1
names: Similarity
messages: Belongs to the RelE toxin family.

1549858:MC45 RS04350
gene id: 1549858:MC45_RS04350
uniprot id: A0A097EDV4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1549858:MC45 RS05735
gene id: 1549858:MC45_RS05735
uniprot id: A0A097EEI5
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1549858:MC45 RS14180
gene id: 1549858:MC45_RS14180
uniprot id: A0A097EIC4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1549858:MC45 RS01995
gene id: 1549858:MC45_RS01995
uniprot id: A0A097ECT0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1549858:MC45 RS11810
gene id: 1549858:MC45_RS11810
uniprot id: A0A097EHB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1549858:MC45 RS11500
gene id: 1549858:MC45_RS11500
uniprot id: A0A097EH45
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1549858:MC45 RS16455
gene id: 1549858:MC45_RS16455
uniprot id: A0A097EJF7
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1549858:MC45 RS12880
gene id: 1549858:MC45_RS12880
uniprot id: A0A097EHR2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1549858:MC45 RS05745
gene id: 1549858:MC45_RS05745
uniprot id: A0A097EEI4
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

1549858:MC45 RS03480
gene id: 1549858:MC45_RS03480
uniprot id: A0A097EDK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1549858:MC45 RS09650
gene id: 1549858:MC45_RS09650
uniprot id: A0A097EG96
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1549858:MC45 RS14030
gene id: 1549858:MC45_RS14030
uniprot id: A0A097EIC7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1549858:MC45 RS10390
gene id: 1549858:MC45_RS10390
uniprot id: A0A097EKQ9
names: Subcellular Location Annotation
messages: Membrane

1549858:MC45 RS02355
gene id: 1549858:MC45_RS02355
uniprot id: A0A097ECZ1
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1549858:MC45 RS09015
gene id: 1549858:MC45_RS09015
uniprot id: A0A097EFY5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1549858:MC45 RS05505
gene id: 1549858:MC45_RS05505
uniprot id: A0A097EEF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS13755
gene id: 1549858:MC45_RS13755
uniprot id: A0A097EI68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1549858:MC45 RS14170
gene id: 1549858:MC45_RS14170
uniprot id: A0A097EIF0
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1549858:MC45 RS17185
gene id: 1549858:MC45_RS17185
uniprot id: A0A097EJR1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1549858:MC45 RS14575
gene id: 1549858:MC45_RS14575
uniprot id: A0A097EIJ9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS09750
gene id: 1549858:MC45_RS09750
uniprot id: A0A097EGC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

1549858:MC45 RS10635
gene id: 1549858:MC45_RS10635
uniprot id: A0A097EGS1
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1549858:MC45 RS00640
gene id: 1549858:MC45_RS00640
uniprot id: A0A097EC86
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1549858:MC45 RS00445
gene id: 1549858:MC45_RS00445
uniprot id: A0A097EC62
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

1549858:MC45 RS15060
gene id: 1549858:MC45_RS15060
uniprot id: A0A097EIS6
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1549858:MC45 RS11690
gene id: 1549858:MC45_RS11690
uniprot id: A0A097EH76
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1549858:MC45 RS03555
gene id: 1549858:MC45_RS03555
uniprot id: A0A097EDL7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1549858:MC45 RS11185
gene id: 1549858:MC45_RS11185
uniprot id: A0A097EH00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1549858:MC45 RS04535
gene id: 1549858:MC45_RS04535
uniprot id: A0A097EDZ9
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1549858:MC45 RS05770
gene id: 1549858:MC45_RS05770
uniprot id: A0A097EEI7
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1549858:MC45 RS09325
gene id: 1549858:MC45_RS09325
uniprot id: A0A097EG39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1549858:MC45 RS01230
gene id: 1549858:MC45_RS01230
uniprot id: A0A097ECG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS03015
gene id: 1549858:MC45_RS03015
uniprot id: A0A097EDA4
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Belongs to the IspF family.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549858:MC45 RS01755
gene id: 1549858:MC45_RS01755
uniprot id: A0A097ECP1
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1549858:MC45 RS14055
gene id: 1549858:MC45_RS14055
uniprot id: A0A097EID1
names: Similarity
messages: Belongs to the peptidase M16 family.

1549858:MC45 RS01805
gene id: 1549858:MC45_RS01805
uniprot id: A0A097ECP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1549858:MC45 RS05130
gene id: 1549858:MC45_RS05130
uniprot id: A0A097EE82
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1549858:MC45 RS11760
gene id: 1549858:MC45_RS11760
uniprot id: A0A097EH98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1549858:MC45 RS02950
gene id: 1549858:MC45_RS02950
uniprot id: A0A097EDC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1549858:MC45 RS05905
gene id: 1549858:MC45_RS05905
uniprot id: A0A097EEL4
names: Similarity
messages: Belongs to the UPF0178 family.

1549858:MC45 RS06075
gene id: 1549858:MC45_RS06075
uniprot id: A0A097EES7
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1549858:MC45 RS18085
gene id: 1549858:MC45_RS18085
uniprot id: A0A097ELI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1549858:MC45 RS02520
gene id: 1549858:MC45_RS02520
uniprot id: A0A097ED53
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1549858:MC45 RS15385
gene id: 1549858:MC45_RS15385
uniprot id: A0A097EIX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1549858:MC45 RS11225
gene id: 1549858:MC45_RS11225
uniprot id: A0A097EGZ7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1549858:MC45 RS04375
gene id: 1549858:MC45_RS04375
uniprot id: A0A097EDX7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1549858:MC45 RS01630
gene id: 1549858:MC45_RS01630
uniprot id: A0A097ECM6
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1549858:MC45 RS04650
gene id: 1549858:MC45_RS04650
uniprot id: A0A097EE18
names: Similarity
messages: Belongs to the UPF0047 family.

1549858:MC45 RS03705
gene id: 1549858:MC45_RS03705
uniprot id: A0A097EK73
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

1549858:MC45 RS14440
gene id: 1549858:MC45_RS14440
uniprot id: A0A097EIG6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1549858:MC45 RS11615
gene id: 1549858:MC45_RS11615
uniprot id: A0A097EH61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1549858:MC45 RS03660
gene id: 1549858:MC45_RS03660
uniprot id: A0A097EDJ2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1549858:MC45 RS08175
gene id: 1549858:MC45_RS08175
uniprot id: A0A097EFK9
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.