1542390:KX01 RS02895
gene id: 1542390:KX01_RS02895
uniprot id: A0A1J0KUZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1542390:KX01 RS03920
gene id: 1542390:KX01_RS03920
uniprot id: A0A1J0KTZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1542390:KX01 RS05995
gene id: 1542390:KX01_RS05995
uniprot id: A0A1J0KT40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1542390:KX01 RS00920
gene id: 1542390:KX01_RS00920
uniprot id: A0A1J0KVI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1542390:KX01 RS00540
gene id: 1542390:KX01_RS00540
uniprot id: A0A1J0KS68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1542390:KX01 RS03590
gene id: 1542390:KX01_RS03590
uniprot id: A0A1J0KSM9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1542390:KX01 RS04840
gene id: 1542390:KX01_RS04840
uniprot id: A0A1J0KRH9
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1542390:KX01 RS07275
gene id: 1542390:KX01_RS07275
uniprot id: A0A1J0KUS5
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1542390:KX01 RS07685
gene id: 1542390:KX01_RS07685
uniprot id: A0A1J0KU67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1542390:KX01 RS06050
gene id: 1542390:KX01_RS06050
uniprot id: A0A1J0KV03
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1542390:KX01 RS03300
gene id: 1542390:KX01_RS03300
uniprot id: A0A1J0KTQ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1542390:KX01 RS05045
gene id: 1542390:KX01_RS05045
uniprot id: A0A1J0KR81
names: Similarity
messages: Belongs to the peptidase S49 family.

1542390:KX01 RS04125
gene id: 1542390:KX01_RS04125
uniprot id: A0A1J0KWK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1542390:KX01 RS08095
gene id: 1542390:KX01_RS08095
uniprot id: A0A1J0KV06
names: Similarity
messages: Belongs to the DapB family.

1542390:KX01 RS00585
gene id: 1542390:KX01_RS00585
uniprot id: A0A1J0KSR8
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1542390:KX01 RS06645
gene id: 1542390:KX01_RS06645
uniprot id: A0A1J0KUD2
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS00790
gene id: 1542390:KX01_RS00790
uniprot id: A0A1J0KRA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1542390:KX01 RS01260
gene id: 1542390:KX01_RS01260
uniprot id: A0A1J0KSV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1542390:KX01 RS08615
gene id: 1542390:KX01_RS08615
uniprot id: A0A1J0KVG2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1542390:KX01 RS05020
gene id: 1542390:KX01_RS05020
uniprot id: A0A1J0KRN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1542390:KX01 RS08920
gene id: 1542390:KX01_RS08920
uniprot id: A0A1J0KT43
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1542390:KX01 RS08930
gene id: 1542390:KX01_RS08930
uniprot id: A0A1J0KSI3
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1542390:KX01 RS06195
gene id: 1542390:KX01_RS06195
uniprot id: A0A1J0KSP9
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1542390:KX01 RS01235
gene id: 1542390:KX01_RS01235
uniprot id: A0A1J0KRZ7
names: Similarity
messages: Belongs to the universal stress protein A family.

1542390:KX01 RS02265
gene id: 1542390:KX01_RS02265
uniprot id: A0A1J0KT71
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS02765
gene id: 1542390:KX01_RS02765
uniprot id: A0A1J0KTW7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1542390:KX01 RS04640
gene id: 1542390:KX01_RS04640
uniprot id: A0A1J0KTG0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1542390:KX01 RS02285
gene id: 1542390:KX01_RS02285
uniprot id: A0A1J0KVN4
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS08800
gene id: 1542390:KX01_RS08800
uniprot id: A0A1J0KTI1
names: Similarity
messages: Belongs to the NAPRTase family.

1542390:KX01 RS02970
gene id: 1542390:KX01_RS02970
uniprot id: A0A1J0KRG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1542390:KX01 RS06055
gene id: 1542390:KX01_RS06055
uniprot id: A0A1J0KW83
names: Similarity
messages: Belongs to the asparaginase 1 family.

1542390:KX01 RS06760
gene id: 1542390:KX01_RS06760
uniprot id: A0A1J0KT96
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

1542390:KX01 RS02795
gene id: 1542390:KX01_RS02795
uniprot id: A0A1J0KTV8
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1542390:KX01 RS00750
gene id: 1542390:KX01_RS00750
uniprot id: A0A1J0KRD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1542390:KX01 RS04790
gene id: 1542390:KX01_RS04790
uniprot id: A0A1J0KW49
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1542390:KX01 RS04030
gene id: 1542390:KX01_RS04030
uniprot id: A0A1J0KUF6
names: Similarity
messages: Belongs to the transposase 8 family.

1542390:KX01 RS01760
gene id: 1542390:KX01_RS01760
uniprot id: A0A1J0KTU4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1542390:KX01 RS07340
gene id: 1542390:KX01_RS07340
uniprot id: A0A1J0KW24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1542390:KX01 RS02615
gene id: 1542390:KX01_RS02615
uniprot id: A0A1J0KTP2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1542390:KX01 RS06095
gene id: 1542390:KX01_RS06095
uniprot id: A0A1J0KUB1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1542390:KX01 RS09090
gene id: 1542390:KX01_RS09090
uniprot id: A0A1J0KWE9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1542390:KX01 RS03325
gene id: 1542390:KX01_RS03325
uniprot id: A0A1J0KT42
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1542390:KX01 RS05230
gene id: 1542390:KX01_RS05230
uniprot id: A0A1J0KS92
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1542390:KX01 RS03175
gene id: 1542390:KX01_RS03175
uniprot id: A0A1J0KVI5
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1542390:KX01 RS07260
gene id: 1542390:KX01_RS07260
uniprot id: A0A1J0KV04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

1542390:KX01 RS01055
gene id: 1542390:KX01_RS01055
uniprot id: A0A1J0KVV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

1542390:KX01 RS04725
gene id: 1542390:KX01_RS04725
uniprot id: A0A1J0KV75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1542390:KX01 RS00420
gene id: 1542390:KX01_RS00420
uniprot id: A0A1J0KU53
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1542390:KX01 RS03850
gene id: 1542390:KX01_RS03850
uniprot id: A0A1J0KUP5
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1542390:KX01 RS02545
gene id: 1542390:KX01_RS02545
uniprot id: A0A1J0KTP8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1542390:KX01 RS03025
gene id: 1542390:KX01_RS03025
uniprot id: A0A1J0KT64
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1542390:KX01 RS01710
gene id: 1542390:KX01_RS01710
uniprot id: A0A1J0KS05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Efflux system for nickel and cobalt.
messages: Membrane

1542390:KX01 RS07975
gene id: 1542390:KX01_RS07975
uniprot id: A0A1J0KSH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1542390:KX01 RS01205
gene id: 1542390:KX01_RS01205
uniprot id: A0A1J0KUX5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1542390:KX01 RS08175
gene id: 1542390:KX01_RS08175
uniprot id: A0A1J0KRW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1542390:KX01 RS05555
gene id: 1542390:KX01_RS05555
uniprot id: A0A1J0KUX9
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1542390:KX01 RS03205
gene id: 1542390:KX01_RS03205
uniprot id: A0A1J0KSD2
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1542390:KX01 RS01950
gene id: 1542390:KX01_RS01950
uniprot id: A0A1J0KW06
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1542390:KX01 RS00855
gene id: 1542390:KX01_RS00855
uniprot id: A0A1J0KVP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1542390:KX01 RS04845
gene id: 1542390:KX01_RS04845
uniprot id: A0A1J0KTG7
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1542390:KX01 RS07710
gene id: 1542390:KX01_RS07710
uniprot id: A0A1J0KTL4
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1542390:KX01 RS01505
gene id: 1542390:KX01_RS01505
uniprot id: A0A1J0KSV9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1542390:KX01 RS07470
gene id: 1542390:KX01_RS07470
uniprot id: A0A1J0KRB7
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

1542390:KX01 RS05985
gene id: 1542390:KX01_RS05985
uniprot id: A0A1J0KRM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1542390:KX01 RS03120
gene id: 1542390:KX01_RS03120
uniprot id: A0A1J0KT80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1542390:KX01 RS03495
gene id: 1542390:KX01_RS03495
uniprot id: A0A1J0KSI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

1542390:KX01 RS05590
gene id: 1542390:KX01_RS05590
uniprot id: A0A1J0KU85
names: Similarity
messages: Belongs to the YjdM family.

1542390:KX01 RS07280
gene id: 1542390:KX01_RS07280
uniprot id: A0A1J0KSZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1542390:KX01 RS02820
gene id: 1542390:KX01_RS02820
uniprot id: A0A1J0KR94
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1542390:KX01 RS05285
gene id: 1542390:KX01_RS05285
uniprot id: A0A1J0KV70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1542390:KX01 RS04830
gene id: 1542390:KX01_RS04830
uniprot id: A0A1J0KW75
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1542390:KX01 RS02840
gene id: 1542390:KX01_RS02840
uniprot id: A0A1J0KTJ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1542390:KX01 RS03360
gene id: 1542390:KX01_RS03360
uniprot id: A0A1J0KSN6
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1542390:KX01 RS04945
gene id: 1542390:KX01_RS04945
uniprot id: A0A1J0KS77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1542390:KX01 RS08760
gene id: 1542390:KX01_RS08760
uniprot id: A0A1J0KUR6
names: Similarity
messages: Belongs to the ArsC family.

1542390:KX01 RS01000
gene id: 1542390:KX01_RS01000
uniprot id: A0A1J0KT81
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1542390:KX01 RS07880
gene id: 1542390:KX01_RS07880
uniprot id: A0A1J0KUQ8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1542390:KX01 RS01045
gene id: 1542390:KX01_RS01045
uniprot id: A0A1J0KVH1
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1542390:KX01 RS06560
gene id: 1542390:KX01_RS06560
uniprot id: A0A1J0KRR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1542390:KX01 RS04260
gene id: 1542390:KX01_RS04260
uniprot id: A0A1J0KS39
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS07110
gene id: 1542390:KX01_RS07110
uniprot id: A0A1J0KTR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

1542390:KX01 RS09120
gene id: 1542390:KX01_RS09120
uniprot id: A0A1J0KT44
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

1542390:KX01 RS00830
gene id: 1542390:KX01_RS00830
uniprot id: A0A1J0KUV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1542390:KX01 RS06040
gene id: 1542390:KX01_RS06040
uniprot id: A0A1J0KUV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1542390:KX01 RS03350
gene id: 1542390:KX01_RS03350
uniprot id: A0A1J0KW84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1542390:KX01 RS02340
gene id: 1542390:KX01_RS02340
uniprot id: A0A1J0KRD7
names: Similarity
messages: Belongs to the WrbA family.

1542390:KX01 RS06305
gene id: 1542390:KX01_RS06305
uniprot id: A0A1J0KVU4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

1542390:KX01 RS02710
gene id: 1542390:KX01_RS02710
uniprot id: A0A1J0KT49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1542390:KX01 RS03140
gene id: 1542390:KX01_RS03140
uniprot id: A0A1J0KUU4
names: Similarity
messages: Belongs to the glutamine synthetase family.

1542390:KX01 RS05265
gene id: 1542390:KX01_RS05265
uniprot id: A0A1J0KTL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

1542390:KX01 RS07740
gene id: 1542390:KX01_RS07740
uniprot id: A0A1J0KRC1
names: Caution
names: Similarity
messages: Belongs to the UPF0391 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1542390:KX01 RS05825
gene id: 1542390:KX01_RS05825
uniprot id: A0A1J0KRG6
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

1542390:KX01 RS02830
gene id: 1542390:KX01_RS02830
uniprot id: A0A1J0KSN4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1542390:KX01 RS04085
gene id: 1542390:KX01_RS04085
uniprot id: A0A1J0KSF0
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS04380
gene id: 1542390:KX01_RS04380
uniprot id: A0A1J0KU59
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1542390:KX01 RS07440
gene id: 1542390:KX01_RS07440
uniprot id: A0A1J0KSG1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1542390:KX01 RS00415
gene id: 1542390:KX01_RS00415
uniprot id: A0A1J0KUL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1542390:KX01 RS01105
gene id: 1542390:KX01_RS01105
uniprot id: A0A1J0KTU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.

1542390:KX01 RS07270
gene id: 1542390:KX01_RS07270
uniprot id: A0A1J0KVW9
names: Similarity
messages: Belongs to the CvfB family.

1542390:KX01 RS05495
gene id: 1542390:KX01_RS05495
uniprot id: A0A1J0KT84
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

1542390:KX01 RS06070
gene id: 1542390:KX01_RS06070
uniprot id: A0A1J0KRB1
names: Similarity
messages: Belongs to the CutC family.

1542390:KX01 RS04835
gene id: 1542390:KX01_RS04835
uniprot id: A0A1J0KW34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1542390:KX01 RS00800
gene id: 1542390:KX01_RS00800
uniprot id: A0A1J0KW61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1542390:KX01 RS00900
gene id: 1542390:KX01_RS00900
uniprot id: A0A1J0KUS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1542390:KX01 RS08575
gene id: 1542390:KX01_RS08575
uniprot id: A0A1J0KUY7
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1542390:KX01 RS07855
gene id: 1542390:KX01_RS07855
uniprot id: A0A1J0KTY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane
messages: Membrane

1542390:KX01 RS07945
gene id: 1542390:KX01_RS07945
uniprot id: A0A1J0KSK3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1542390:KX01 RS07125
gene id: 1542390:KX01_RS07125
uniprot id: A0A1J0KW48
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 zinc ion per subunit.

1542390:KX01 RS07545
gene id: 1542390:KX01_RS07545
uniprot id: A0A1J0KVV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

1542390:KX01 RS03450
gene id: 1542390:KX01_RS03450
uniprot id: A0A1J0KTT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

1542390:KX01 RS05300
gene id: 1542390:KX01_RS05300
uniprot id: A0A1J0KVT9
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1542390:KX01 RS07820
gene id: 1542390:KX01_RS07820
uniprot id: A0A1J0KUM9
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS04250
gene id: 1542390:KX01_RS04250
uniprot id: A0A1J0KUV4
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1542390:KX01 RS05660
gene id: 1542390:KX01_RS05660
uniprot id: A0A1J0KRQ1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1542390:KX01 RS07815
gene id: 1542390:KX01_RS07815
uniprot id: A0A1J0KU24
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1542390:KX01 RS05550
gene id: 1542390:KX01_RS05550
uniprot id: A0A1J0KSZ8
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1542390:KX01 RS06165
gene id: 1542390:KX01_RS06165
uniprot id: A0A1J0KS96
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS07450
gene id: 1542390:KX01_RS07450
uniprot id: A0A1J0KVS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1542390:KX01 RS07120
gene id: 1542390:KX01_RS07120
uniprot id: A0A1J0KRP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1542390:KX01 RS08520
gene id: 1542390:KX01_RS08520
uniprot id: A0A1J0KUC3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1542390:KX01 RS05295
gene id: 1542390:KX01_RS05295
uniprot id: A0A1J0KV53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1542390:KX01 RS06770
gene id: 1542390:KX01_RS06770
uniprot id: A0A1J0KVP3
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1542390:KX01 RS05140
gene id: 1542390:KX01_RS05140
uniprot id: A0A1J0KUX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

1542390:KX01 RS01810
gene id: 1542390:KX01_RS01810
uniprot id: A0A1J0KTP4
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1542390:KX01 RS06025
gene id: 1542390:KX01_RS06025
uniprot id: A0A1J0KTW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1542390:KX01 RS02880
gene id: 1542390:KX01_RS02880
uniprot id: A0A1J0KRY5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1542390:KX01 RS09200
gene id: 1542390:KX01_RS09200
uniprot id: A0A1J0KSB4
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS02535
gene id: 1542390:KX01_RS02535
uniprot id: A0A1J0KSG4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

1542390:KX01 RS07980
gene id: 1542390:KX01_RS07980
uniprot id: A0A1J0KVT4
names: Function
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.

1542390:KX01 RS00725
gene id: 1542390:KX01_RS00725
uniprot id: A0A1J0KS40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1542390:KX01 RS00850
gene id: 1542390:KX01_RS00850
uniprot id: A0A1J0KU13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1542390:KX01 RS09080
gene id: 1542390:KX01_RS09080
uniprot id: A0A1J0KV28
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1542390:KX01 RS00375
gene id: 1542390:KX01_RS00375
uniprot id: A0A1J0KRL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1542390:KX01 RS06290
gene id: 1542390:KX01_RS06290
uniprot id: A0A1J0KTK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1542390:KX01 RS07030
gene id: 1542390:KX01_RS07030
uniprot id: A0A1J0KTJ6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1542390:KX01 RS08310
gene id: 1542390:KX01_RS08310
uniprot id: A0A1J0KRH2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1542390:KX01 RS08085
gene id: 1542390:KX01_RS08085
uniprot id: A0A1J0KTL6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1542390:KX01 RS07220
gene id: 1542390:KX01_RS07220
uniprot id: A0A1J0KU15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1542390:KX01 RS04020
gene id: 1542390:KX01_RS04020
uniprot id: A0A1J0KS70
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1542390:KX01 RS06260
gene id: 1542390:KX01_RS06260
uniprot id: A0A1J0KWA5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1542390:KX01 RS05305
gene id: 1542390:KX01_RS05305
uniprot id: A0A1J0KW04
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1542390:KX01 RS03795
gene id: 1542390:KX01_RS03795
uniprot id: A0A1J0KR47
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1542390:KX01 RS06845
gene id: 1542390:KX01_RS06845
uniprot id: A0A1J0KSP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1542390:KX01 RS07050
gene id: 1542390:KX01_RS07050
uniprot id: A0A1J0KVU0
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1542390:KX01 RS06575
gene id: 1542390:KX01_RS06575
uniprot id: A0A1J0KV23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

1542390:KX01 RS08560
gene id: 1542390:KX01_RS08560
uniprot id: A0A1J0KTE7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

1542390:KX01 RS02850
gene id: 1542390:KX01_RS02850
uniprot id: A0A1J0KWD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1542390:KX01 RS03275
gene id: 1542390:KX01_RS03275
uniprot id: A0A1J0KVM0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1542390:KX01 RS07345
gene id: 1542390:KX01_RS07345
uniprot id: A0A1J0KTX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1542390:KX01 RS02040
gene id: 1542390:KX01_RS02040
uniprot id: A0A1J0KSG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1542390:KX01 RS08490
gene id: 1542390:KX01_RS08490
uniprot id: A0A1J0KW62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1542390:KX01 RS04620
gene id: 1542390:KX01_RS04620
uniprot id: A0A1J0KVT8
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1542390:KX01 RS08845
gene id: 1542390:KX01_RS08845
uniprot id: A0A1J0KRU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1542390:KX01 RS02740
gene id: 1542390:KX01_RS02740
uniprot id: A0A1J0KV88
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1542390:KX01 RS05330
gene id: 1542390:KX01_RS05330
uniprot id: A0A1J0KUE1
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1542390:KX01 RS01970
gene id: 1542390:KX01_RS01970
uniprot id: A0A1J0KVZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1542390:KX01 RS07215
gene id: 1542390:KX01_RS07215
uniprot id: A0A1J0KUD6
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS02990
gene id: 1542390:KX01_RS02990
uniprot id: A0A1J0KVK0
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS03975
gene id: 1542390:KX01_RS03975
uniprot id: A0A1J0KSQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1542390:KX01 RS04105
gene id: 1542390:KX01_RS04105
uniprot id: A0A1J0KTQ2
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

1542390:KX01 RS01240
gene id: 1542390:KX01_RS01240
uniprot id: A0A1J0KUS1
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS09195
gene id: 1542390:KX01_RS09195
uniprot id: A0A1J0KRU7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1542390:KX01 RS03735
gene id: 1542390:KX01_RS03735
uniprot id: A0A1J0KUE4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1542390:KX01 RS08570
gene id: 1542390:KX01_RS08570
uniprot id: A0A1J0KWD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1542390:KX01 RS07800
gene id: 1542390:KX01_RS07800
uniprot id: A0A1J0KT00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1542390:KX01 RS04930
gene id: 1542390:KX01_RS04930
uniprot id: A0A1J0KTN9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1542390:KX01 RS04760
gene id: 1542390:KX01_RS04760
uniprot id: A0A1J0KS82
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1542390:KX01 RS02380
gene id: 1542390:KX01_RS02380
uniprot id: A0A1J0KTC2
names: Similarity
messages: Belongs to the asparagine synthetase family.

1542390:KX01 RS03615
gene id: 1542390:KX01_RS03615
uniprot id: A0A1J0KVF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1542390:KX01 RS04675
gene id: 1542390:KX01_RS04675
uniprot id: A0A1J0KTY4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1542390:KX01 RS04460
gene id: 1542390:KX01_RS04460
uniprot id: A0A1J0KVX0
names: Similarity
messages: Belongs to the SufE family.

1542390:KX01 RS03965
gene id: 1542390:KX01_RS03965
uniprot id: A0A1J0KRH6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1542390:KX01 RS05710
gene id: 1542390:KX01_RS05710
uniprot id: A0A1J0KVC1
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1542390:KX01 RS01510
gene id: 1542390:KX01_RS01510
uniprot id: A0A1J0KVV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.

1542390:KX01 RS05475
gene id: 1542390:KX01_RS05475
uniprot id: A0A1J0KT25
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1542390:KX01 RS04825
gene id: 1542390:KX01_RS04825
uniprot id: A0A1J0KRJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1542390:KX01 RS05725
gene id: 1542390:KX01_RS05725
uniprot id: A0A1J0KSJ0
names: Similarity
messages: Belongs to the ArsC family.

1542390:KX01 RS04025
gene id: 1542390:KX01_RS04025
uniprot id: A0A1J0KV45
names: Subcellular Location Annotation
messages: Cytoplasm

1542390:KX01 RS03745
gene id: 1542390:KX01_RS03745
uniprot id: A0A1J0KUB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1542390:KX01 RS02660
gene id: 1542390:KX01_RS02660
uniprot id: A0A1J0KS57
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1542390:KX01 RS07390
gene id: 1542390:KX01_RS07390
uniprot id: A0A1J0KUA4
names: Similarity
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

1542390:KX01 RS05560
gene id: 1542390:KX01_RS05560
uniprot id: A0A1J0KW39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1542390:KX01 RS07560
gene id: 1542390:KX01_RS07560
uniprot id: A0A1J0KUT0
names: Similarity
messages: Belongs to the UPF0250 family.

1542390:KX01 RS02230
gene id: 1542390:KX01_RS02230
uniprot id: A0A1J0KU99
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1542390:KX01 RS03635
gene id: 1542390:KX01_RS03635
uniprot id: A0A1J0KSI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1542390:KX01 RS06005
gene id: 1542390:KX01_RS06005
uniprot id: A0A1J0KRZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1542390:KX01 RS08195
gene id: 1542390:KX01_RS08195
uniprot id: A0A1J0KSW6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1542390:KX01 RS08475
gene id: 1542390:KX01_RS08475
uniprot id: A0A1J0KRN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1542390:KX01 RS06950
gene id: 1542390:KX01_RS06950
uniprot id: A0A1J0KU23
names: Similarity
messages: Belongs to the peptidase M17 family.

1542390:KX01 RS08040
gene id: 1542390:KX01_RS08040
uniprot id: A0A1J0KRU8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1542390:KX01 RS09005
gene id: 1542390:KX01_RS09005
uniprot id: A0A1J0KV21
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1542390:KX01 RS06590
gene id: 1542390:KX01_RS06590
uniprot id: A0A1J0KUA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1542390:KX01 RS08720
gene id: 1542390:KX01_RS08720
uniprot id: A0A1J0KTT0
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1542390:KX01 RS04695
gene id: 1542390:KX01_RS04695
uniprot id: A0A1J0KU51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1542390:KX01 RS04920
gene id: 1542390:KX01_RS04920
uniprot id: A0A1J0KR45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1542390:KX01 RS03825
gene id: 1542390:KX01_RS03825
uniprot id: A0A1J0KV77
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 3 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1542390:KX01 RS05850
gene id: 1542390:KX01_RS05850
uniprot id: A0A1J0KU96
names: Similarity
messages: Belongs to the CFA/CMAS family.

1542390:KX01 RS07510
gene id: 1542390:KX01_RS07510
uniprot id: A0A1J0KTF5
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS07375
gene id: 1542390:KX01_RS07375
uniprot id: A0A1J0KSW4
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1542390:KX01 RS03510
gene id: 1542390:KX01_RS03510
uniprot id: A0A1J0KQZ4
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

1542390:KX01 RS07990
gene id: 1542390:KX01_RS07990
uniprot id: A0A1J0KVR9
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

1542390:KX01 RS06345
gene id: 1542390:KX01_RS06345
uniprot id: A0A1J0KS16
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1542390:KX01 RS02940
gene id: 1542390:KX01_RS02940
uniprot id: A0A1J0KTH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1542390:KX01 RS03090
gene id: 1542390:KX01_RS03090
uniprot id: A0A1J0KT26
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1542390:KX01 RS03685
gene id: 1542390:KX01_RS03685
uniprot id: A0A1J0KRS1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1542390:KX01 RS08980
gene id: 1542390:KX01_RS08980
uniprot id: A0A1J0KUW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1542390:KX01 RS02905
gene id: 1542390:KX01_RS02905
uniprot id: A0A1J0KTL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1542390:KX01 RS00090
gene id: 1542390:KX01_RS00090
uniprot id: A0A1J0KT38
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1542390:KX01 RS08695
gene id: 1542390:KX01_RS08695
uniprot id: A0A1J0KSQ1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1542390:KX01 RS00735
gene id: 1542390:KX01_RS00735
uniprot id: A0A1J0KU28
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS02170
gene id: 1542390:KX01_RS02170
uniprot id: A0A1J0KRI5
names: Subunit
messages: Homodimer.

1542390:KX01 RS01150
gene id: 1542390:KX01_RS01150
uniprot id: A0A1J0KVU7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1542390:KX01 RS06830
gene id: 1542390:KX01_RS06830
uniprot id: A0A1J0KT62
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1542390:KX01 RS02585
gene id: 1542390:KX01_RS02585
uniprot id: A0A1J0KR46
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1542390:KX01 RS03860
gene id: 1542390:KX01_RS03860
uniprot id: A0A1J0KT01
names: Similarity
messages: Belongs to the Skp family.

1542390:KX01 RS05380
gene id: 1542390:KX01_RS05380
uniprot id: A0A1J0KV46
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1542390:KX01 RS08320
gene id: 1542390:KX01_RS08320
uniprot id: A0A1J0KVT6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1542390:KX01 RS08700
gene id: 1542390:KX01_RS08700
uniprot id: A0A1J0KV85
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1542390:KX01 RS03280
gene id: 1542390:KX01_RS03280
uniprot id: A0A1J0KVV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1542390:KX01 RS00440
gene id: 1542390:KX01_RS00440
uniprot id: A0A1J0KVS3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1542390:KX01 RS08015
gene id: 1542390:KX01_RS08015
uniprot id: A0A1J0KT75
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1542390:KX01 RS02175
gene id: 1542390:KX01_RS02175
uniprot id: A0A1J0KVA4
names: Similarity
messages: Belongs to the TrpC family.
messages: Belongs to the TrpF family.

1542390:KX01 RS07580
gene id: 1542390:KX01_RS07580
uniprot id: A0A1J0KRC4
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.

1542390:KX01 RS05260
gene id: 1542390:KX01_RS05260
uniprot id: A0A1J0KVY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Protein-1 exporter (TC 3.A.1.109) family.
messages: Membrane

1542390:KX01 RS03070
gene id: 1542390:KX01_RS03070
uniprot id: A0A1J0KSA3
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1542390:KX01 RS03585
gene id: 1542390:KX01_RS03585
uniprot id: A0A1J0KT67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1542390:KX01 RS00100
gene id: 1542390:KX01_RS00100
uniprot id: A0A1J0KUQ5
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1542390:KX01 RS08445
gene id: 1542390:KX01_RS08445
uniprot id: A0A1J0KRR8
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1542390:KX01 RS00965
gene id: 1542390:KX01_RS00965
uniprot id: A0A1J0KUG0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1542390:KX01 RS05150
gene id: 1542390:KX01_RS05150
uniprot id: A0A1J0KVP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1542390:KX01 RS02645
gene id: 1542390:KX01_RS02645
uniprot id: A0A1J0KSJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1542390:KX01 RS03625
gene id: 1542390:KX01_RS03625
uniprot id: A0A1J0KVP1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1542390:KX01 RS08305
gene id: 1542390:KX01_RS08305
uniprot id: A0A1J0KT95
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

1542390:KX01 RS03980
gene id: 1542390:KX01_RS03980
uniprot id: A0A1J0KT35
names: Similarity
messages: Belongs to the pirin family.

1542390:KX01 RS07960
gene id: 1542390:KX01_RS07960
uniprot id: A0A1J0KTF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1542390:KX01 RS05750
gene id: 1542390:KX01_RS05750
uniprot id: A0A1J0KTU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1542390:KX01 RS08330
gene id: 1542390:KX01_RS08330
uniprot id: A0A1J0KVN1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1542390:KX01 RS05155
gene id: 1542390:KX01_RS05155
uniprot id: A0A1J0KVX3
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1542390:KX01 RS01785
gene id: 1542390:KX01_RS01785
uniprot id: A0A1J0KS78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1542390:KX01 RS00495
gene id: 1542390:KX01_RS00495
uniprot id: A0A1J0KW33
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1542390:KX01 RS00065
gene id: 1542390:KX01_RS00065
uniprot id: A0A1J0KUA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1542390:KX01 RS00350
gene id: 1542390:KX01_RS00350
uniprot id: A0A1J0KST8
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1542390:KX01 RS02565
gene id: 1542390:KX01_RS02565
uniprot id: A0A1J0KW97
names: Similarity
messages: Belongs to the nitroreductase family.

1542390:KX01 RS01805
gene id: 1542390:KX01_RS01805
uniprot id: A0A1J0KST4
names: Function
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1542390:KX01 RS03530
gene id: 1542390:KX01_RS03530
uniprot id: A0A1J0KUD3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1542390:KX01 RS00575
gene id: 1542390:KX01_RS00575
uniprot id: A0A1J0KTZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1542390:KX01 RS04100
gene id: 1542390:KX01_RS04100
uniprot id: A0A1J0KU89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1542390:KX01 RS07290
gene id: 1542390:KX01_RS07290
uniprot id: A0A1J0KUY9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1542390:KX01 RS03340
gene id: 1542390:KX01_RS03340
uniprot id: A0A1J0KRF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1542390:KX01 RS02985
gene id: 1542390:KX01_RS02985
uniprot id: A0A1J0KT23
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

1542390:KX01 RS02860
gene id: 1542390:KX01_RS02860
uniprot id: A0A1J0KRH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1542390:KX01 RS05955
gene id: 1542390:KX01_RS05955
uniprot id: A0A1J0KVF7
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1542390:KX01 RS01060
gene id: 1542390:KX01_RS01060
uniprot id: A0A1J0KTG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

1542390:KX01 RS04435
gene id: 1542390:KX01_RS04435
uniprot id: A0A1J0KW37
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1542390:KX01 RS01095
gene id: 1542390:KX01_RS01095
uniprot id: A0A1J0KSI4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1542390:KX01 RS08485
gene id: 1542390:KX01_RS08485
uniprot id: A0A1J0KS99
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS07995
gene id: 1542390:KX01_RS07995
uniprot id: A0A1J0KVL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1542390:KX01 RS07500
gene id: 1542390:KX01_RS07500
uniprot id: A0A1J0KTU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1542390:KX01 RS05290
gene id: 1542390:KX01_RS05290
uniprot id: A0A1J0KRY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1542390:KX01 RS00645
gene id: 1542390:KX01_RS00645
uniprot id: A0A1J0KUL0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1542390:KX01 RS01995
gene id: 1542390:KX01_RS01995
uniprot id: A0A1J0KSU2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1542390:KX01 RS00170
gene id: 1542390:KX01_RS00170
uniprot id: A0A1J0KUL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1542390:KX01 RS01500
gene id: 1542390:KX01_RS01500
uniprot id: A0A1J0KUI0
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1542390:KX01 RS05775
gene id: 1542390:KX01_RS05775
uniprot id: A0A1J0KSE5
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1542390:KX01 RS01325
gene id: 1542390:KX01_RS01325
uniprot id: A0A1J0KU39
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1542390:KX01 RS02080
gene id: 1542390:KX01_RS02080
uniprot id: A0A1J0KVB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

1542390:KX01 RS08100
gene id: 1542390:KX01_RS08100
uniprot id: A0A1J0KSJ3
names: Similarity
messages: Belongs to the aspartokinase family.

1542390:KX01 RS05790
gene id: 1542390:KX01_RS05790
uniprot id: A0A1J0KTA8
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1542390:KX01 RS03320
gene id: 1542390:KX01_RS03320
uniprot id: A0A1J0KSM6
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS08390
gene id: 1542390:KX01_RS08390
uniprot id: A0A1J0KUV5
names: Similarity
messages: Belongs to the thioredoxin family.

1542390:KX01 RS03910
gene id: 1542390:KX01_RS03910
uniprot id: A0A1J0KST3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1542390:KX01 RS04155
gene id: 1542390:KX01_RS04155
uniprot id: A0A1J0KUQ7
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1542390:KX01 RS00805
gene id: 1542390:KX01_RS00805
uniprot id: A0A1J0KW51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1542390:KX01 RS03330
gene id: 1542390:KX01_RS03330
uniprot id: A0A1J0KSD4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1542390:KX01 RS02930
gene id: 1542390:KX01_RS02930
uniprot id: A0A1J0KT41
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS07130
gene id: 1542390:KX01_RS07130
uniprot id: A0A1J0KVL5
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

1542390:KX01 RS08805
gene id: 1542390:KX01_RS08805
uniprot id: A0A1J0KW02
names: Similarity
messages: Belongs to the arginase family.

1542390:KX01 RS01090
gene id: 1542390:KX01_RS01090
uniprot id: A0A1J0KSZ2
names: Similarity
messages: Belongs to the threonine synthase family.

1542390:KX01 RS09015
gene id: 1542390:KX01_RS09015
uniprot id: A0A1J0KSU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1542390:KX01 RS04965
gene id: 1542390:KX01_RS04965
uniprot id: A0A1J0KS53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1542390:KX01 RS00020
gene id: 1542390:KX01_RS00020
uniprot id: A0A1J0KTZ2
names: Similarity
messages: Belongs to the bacterial glucokinase family.

1542390:KX01 RS00120
gene id: 1542390:KX01_RS00120
uniprot id: A0A1J0KTT1
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS00665
gene id: 1542390:KX01_RS00665
uniprot id: A0A1J0KTT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

1542390:KX01 RS01605
gene id: 1542390:KX01_RS01605
uniprot id: A0A1J0KSA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1542390:KX01 RS05085
gene id: 1542390:KX01_RS05085
uniprot id: A0A1J0KW00
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

1542390:KX01 RS01075
gene id: 1542390:KX01_RS01075
uniprot id: A0A1J0KRV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1542390:KX01 RS01725
gene id: 1542390:KX01_RS01725
uniprot id: A0A1J0KV97
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1542390:KX01 RS06245
gene id: 1542390:KX01_RS06245
uniprot id: A0A1J0KRU1
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1542390:KX01 RS06015
gene id: 1542390:KX01_RS06015
uniprot id: A0A1J0KVJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1542390:KX01 RS08900
gene id: 1542390:KX01_RS08900
uniprot id: A0A1J0KTH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1542390:KX01 RS07735
gene id: 1542390:KX01_RS07735
uniprot id: A0A1J0KS22
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

1542390:KX01 RS08505
gene id: 1542390:KX01_RS08505
uniprot id: A0A1J0KVI4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1542390:KX01 RS05465
gene id: 1542390:KX01_RS05465
uniprot id: A0A1J0KTV4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1542390:KX01 RS06190
gene id: 1542390:KX01_RS06190
uniprot id: A0A1J0KU16
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1542390:KX01 RS09140
gene id: 1542390:KX01_RS09140
uniprot id: A0A1J0KU10
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

1542390:KX01 RS06450
gene id: 1542390:KX01_RS06450
uniprot id: A0A1J0KRJ0
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1542390:KX01 RS08090
gene id: 1542390:KX01_RS08090
uniprot id: A0A1J0KUF5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1542390:KX01 RS04700
gene id: 1542390:KX01_RS04700
uniprot id: A0A1J0KRV2
names: Function
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

1542390:KX01 RS04960
gene id: 1542390:KX01_RS04960
uniprot id: A0A1J0KS74
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1542390:KX01 RS05645
gene id: 1542390:KX01_RS05645
uniprot id: A0A1J0KUC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1542390:KX01 RS07955
gene id: 1542390:KX01_RS07955
uniprot id: A0A1J0KUH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1542390:KX01 RS08215
gene id: 1542390:KX01_RS08215
uniprot id: A0A1J0KTX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1542390:KX01 RS06985
gene id: 1542390:KX01_RS06985
uniprot id: A0A1J0KUG5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1542390:KX01 RS02695
gene id: 1542390:KX01_RS02695
uniprot id: A0A1J0KTW3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1542390:KX01 RS00650
gene id: 1542390:KX01_RS00650
uniprot id: A0A1J0KSM0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1542390:KX01 RS05345
gene id: 1542390:KX01_RS05345
uniprot id: A0A1J0KRM4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

1542390:KX01 RS04095
gene id: 1542390:KX01_RS04095
uniprot id: A0A1J0KUM8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1542390:KX01 RS08130
gene id: 1542390:KX01_RS08130
uniprot id: A0A1J0KVR2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

1542390:KX01 RS07555
gene id: 1542390:KX01_RS07555
uniprot id: A0A1J0KTB2
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1542390:KX01 RS06820
gene id: 1542390:KX01_RS06820
uniprot id: A0A1J0KV12
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1542390:KX01 RS01750
gene id: 1542390:KX01_RS01750
uniprot id: A0A1J0KTH5
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

1542390:KX01 RS03310
gene id: 1542390:KX01_RS03310
uniprot id: A0A1J0KSV3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1542390:KX01 RS00165
gene id: 1542390:KX01_RS00165
uniprot id: A0A1J0KV17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1542390:KX01 RS08285
gene id: 1542390:KX01_RS08285
uniprot id: A0A1J0KUW1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1542390:KX01 RS05375
gene id: 1542390:KX01_RS05375
uniprot id: A0A1J0KUI6
names: Similarity
messages: Belongs to the BolA/IbaG family.

1542390:KX01 RS02935
gene id: 1542390:KX01_RS02935
uniprot id: A0A1J0KSY6
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS08180
gene id: 1542390:KX01_RS08180
uniprot id: A0A1J0KT17
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1542390:KX01 RS06520
gene id: 1542390:KX01_RS06520
uniprot id: A0A1J0KSZ3
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS01945
gene id: 1542390:KX01_RS01945
uniprot id: A0A1J0KV22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1542390:KX01 RS07715
gene id: 1542390:KX01_RS07715
uniprot id: A0A1J0KSV8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1542390:KX01 RS00295
gene id: 1542390:KX01_RS00295
uniprot id: A0A1J0KU55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1542390:KX01 RS07300
gene id: 1542390:KX01_RS07300
uniprot id: A0A1J0KU81
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

1542390:KX01 RS04850
gene id: 1542390:KX01_RS04850
uniprot id: A0A1J0KV02
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1542390:KX01 RS04905
gene id: 1542390:KX01_RS04905
uniprot id: A0A1J0KTD8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1542390:KX01 RS04805
gene id: 1542390:KX01_RS04805
uniprot id: A0A1J0KW38
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1542390:KX01 RS06740
gene id: 1542390:KX01_RS06740
uniprot id: A0A1J0KUE6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1542390:KX01 RS06550
gene id: 1542390:KX01_RS06550
uniprot id: A0A1J0KTS3
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1542390:KX01 RS00845
gene id: 1542390:KX01_RS00845
uniprot id: A0A1J0KV25
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1542390:KX01 RS08885
gene id: 1542390:KX01_RS08885
uniprot id: A0A1J0KTY9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1542390:KX01 RS09115
gene id: 1542390:KX01_RS09115
uniprot id: A0A1J0KUI7
names: Similarity
messages: Belongs to the peptidase M16 family.

1542390:KX01 RS00885
gene id: 1542390:KX01_RS00885
uniprot id: A0A1J0KRT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1542390:KX01 RS00760
gene id: 1542390:KX01_RS00760
uniprot id: A0A1J0KRW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1542390:KX01 RS01985
gene id: 1542390:KX01_RS01985
uniprot id: A0A1J0KW68
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1542390:KX01 RS05400
gene id: 1542390:KX01_RS05400
uniprot id: A0A1J0KU47
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1542390:KX01 RS01835
gene id: 1542390:KX01_RS01835
uniprot id: A0A1J0KVJ0
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS03215
gene id: 1542390:KX01_RS03215
uniprot id: A0A1J0KVY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1542390:KX01 RS08270
gene id: 1542390:KX01_RS08270
uniprot id: A0A1J0KST5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1542390:KX01 RS02435
gene id: 1542390:KX01_RS02435
uniprot id: A0A1J0KT03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1542390:KX01 RS05350
gene id: 1542390:KX01_RS05350
uniprot id: A0A1J0KUT6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1542390:KX01 RS08265
gene id: 1542390:KX01_RS08265
uniprot id: A0A1J0KVB9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

1542390:KX01 RS04690
gene id: 1542390:KX01_RS04690
uniprot id: A0A1J0KS04
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Homodimer.

1542390:KX01 RS07205
gene id: 1542390:KX01_RS07205
uniprot id: A0A1J0KTC7
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1542390:KX01 RS02420
gene id: 1542390:KX01_RS02420
uniprot id: A0A1J0KTA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1542390:KX01 RS01230
gene id: 1542390:KX01_RS01230
uniprot id: A0A1J0KRC8
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS07930
gene id: 1542390:KX01_RS07930
uniprot id: A0A1J0KV84
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS08275
gene id: 1542390:KX01_RS08275
uniprot id: A0A1J0KV87
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1542390:KX01 RS06505
gene id: 1542390:KX01_RS06505
uniprot id: A0A1J0KRV5
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1542390:KX01 RS00010
gene id: 1542390:KX01_RS00010
uniprot id: A0A1J0KT36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1542390:KX01 RS03570
gene id: 1542390:KX01_RS03570
uniprot id: A0A1J0KWJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1542390:KX01 RS08780
gene id: 1542390:KX01_RS08780
uniprot id: A0A1J0KTJ9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1542390:KX01 RS03730
gene id: 1542390:KX01_RS03730
uniprot id: A0A1J0KUK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1542390:KX01 RS05735
gene id: 1542390:KX01_RS05735
uniprot id: A0A1J0KVI1
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

1542390:KX01 RS08990
gene id: 1542390:KX01_RS08990
uniprot id: A0A1J0KWA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1542390:KX01 RS02355
gene id: 1542390:KX01_RS02355
uniprot id: A0A1J0KW63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1542390:KX01 RS00185
gene id: 1542390:KX01_RS00185
uniprot id: A0A1J0KT69
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1542390:KX01 RS04710
gene id: 1542390:KX01_RS04710
uniprot id: A0A1J0KTQ3
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1542390:KX01 RS03820
gene id: 1542390:KX01_RS03820
uniprot id: A0A1J0KSQ0
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1542390:KX01 RS00210
gene id: 1542390:KX01_RS00210
uniprot id: A0A1J0KTJ8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1542390:KX01 RS03160
gene id: 1542390:KX01_RS03160
uniprot id: A0A1J0KT30
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1542390:KX01 RS03180
gene id: 1542390:KX01_RS03180
uniprot id: A0A1J0KU90
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS00155
gene id: 1542390:KX01_RS00155
uniprot id: A0A1J0KR63
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1542390:KX01 RS02590
gene id: 1542390:KX01_RS02590
uniprot id: A0A1J0KSX1
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS03810
gene id: 1542390:KX01_RS03810
uniprot id: A0A1J0KRR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1542390:KX01 RS02130
gene id: 1542390:KX01_RS02130
uniprot id: A0A1J0KT46
names: Cofactor
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.

1542390:KX01 RS04130
gene id: 1542390:KX01_RS04130
uniprot id: A0A1J0KTH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

1542390:KX01 RS08000
gene id: 1542390:KX01_RS08000
uniprot id: A0A1J0KRJ5
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1542390:KX01 RS06020
gene id: 1542390:KX01_RS06020
uniprot id: A0A1J0KUU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1542390:KX01 RS01745
gene id: 1542390:KX01_RS01745
uniprot id: A0A1J0KRY9
names: Similarity
messages: Belongs to the HupF/HypC family.

1542390:KX01 RS04110
gene id: 1542390:KX01_RS04110
uniprot id: A0A1J0KUQ0
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1542390:KX01 RS07080
gene id: 1542390:KX01_RS07080
uniprot id: A0A1J0KTF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1542390:KX01 RS01675
gene id: 1542390:KX01_RS01675
uniprot id: A0A1J0KTL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

1542390:KX01 RS00905
gene id: 1542390:KX01_RS00905
uniprot id: A0A1J0KW01
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1542390:KX01 RS05365
gene id: 1542390:KX01_RS05365
uniprot id: A0A1J0KS41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1542390:KX01 RS04295
gene id: 1542390:KX01_RS04295
uniprot id: A0A1J0KTI8
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS06900
gene id: 1542390:KX01_RS06900
uniprot id: A0A1J0KTR1
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS08225
gene id: 1542390:KX01_RS08225
uniprot id: A0A1J0KSS5
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS02955
gene id: 1542390:KX01_RS02955
uniprot id: A0A1J0KRC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1542390:KX01 RS02255
gene id: 1542390:KX01_RS02255
uniprot id: A0A1J0KUZ1
names: Similarity
messages: Belongs to the Fur family.

1542390:KX01 RS00720
gene id: 1542390:KX01_RS00720
uniprot id: A0A1J0KU11
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1542390:KX01 RS00370
gene id: 1542390:KX01_RS00370
uniprot id: A0A1J0KT60
names: Similarity
messages: Belongs to the UPF0246 family.

1542390:KX01 RS00715
gene id: 1542390:KX01_RS00715
uniprot id: A0A1J0KRP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1542390:KX01 RS06585
gene id: 1542390:KX01_RS06585
uniprot id: A0A1J0KR54
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1542390:KX01 RS02915
gene id: 1542390:KX01_RS02915
uniprot id: A0A1J0KW93
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS02770
gene id: 1542390:KX01_RS02770
uniprot id: A0A1J0KS79
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1542390:KX01 RS06470
gene id: 1542390:KX01_RS06470
uniprot id: A0A1J0KT98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1542390:KX01 RS00580
gene id: 1542390:KX01_RS00580
uniprot id: A0A1J0KRP8
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

1542390:KX01 RS03870
gene id: 1542390:KX01_RS03870
uniprot id: A0A1J0KRH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1542390:KX01 RS02045
gene id: 1542390:KX01_RS02045
uniprot id: A0A1J0KVN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1542390:KX01 RS08860
gene id: 1542390:KX01_RS08860
uniprot id: A0A1J0KSF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1542390:KX01 RS06555
gene id: 1542390:KX01_RS06555
uniprot id: A0A1J0KTP0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1542390:KX01 RS04050
gene id: 1542390:KX01_RS04050
uniprot id: A0A1J0KVB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1542390:KX01 RS08115
gene id: 1542390:KX01_RS08115
uniprot id: A0A1J0KW23
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1542390:KX01 RS04365
gene id: 1542390:KX01_RS04365
uniprot id: A0A1J0KS63
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

1542390:KX01 RS02035
gene id: 1542390:KX01_RS02035
uniprot id: A0A1J0KVD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1542390:KX01 RS01700
gene id: 1542390:KX01_RS01700
uniprot id: A0A1J0KST2
names: Similarity
messages: Belongs to the peptidase A31 family.

1542390:KX01 RS08455
gene id: 1542390:KX01_RS08455
uniprot id: A0A1J0KUF3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1542390:KX01 RS02715
gene id: 1542390:KX01_RS02715
uniprot id: A0A1J0KTI6
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1542390:KX01 RS03900
gene id: 1542390:KX01_RS03900
uniprot id: A0A1J0KW09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP.
messages: Membrane

1542390:KX01 RS08735
gene id: 1542390:KX01_RS08735
uniprot id: A0A1J0KS66
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1542390:KX01 RS02215
gene id: 1542390:KX01_RS02215
uniprot id: A0A1J0KRE1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1542390:KX01 RS02900
gene id: 1542390:KX01_RS02900
uniprot id: A0A1J0KUK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1542390:KX01 RS05000
gene id: 1542390:KX01_RS05000
uniprot id: A0A1J0KUV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1542390:KX01 RS08590
gene id: 1542390:KX01_RS08590
uniprot id: A0A1J0KUP9
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1542390:KX01 RS07195
gene id: 1542390:KX01_RS07195
uniprot id: A0A1J0KSL4
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

1542390:KX01 RS08535
gene id: 1542390:KX01_RS08535
uniprot id: A0A1J0KV95
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1542390:KX01 RS02790
gene id: 1542390:KX01_RS02790
uniprot id: A0A1J0KSX5
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS02815
gene id: 1542390:KX01_RS02815
uniprot id: A0A1J0KUR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1542390:KX01 RS07170
gene id: 1542390:KX01_RS07170
uniprot id: A0A1J0KS61
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS05010
gene id: 1542390:KX01_RS05010
uniprot id: A0A1J0KWL0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1542390:KX01 RS03440
gene id: 1542390:KX01_RS03440
uniprot id: A0A1J0KVQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1542390:KX01 RS08230
gene id: 1542390:KX01_RS08230
uniprot id: A0A1J0KV36
names: Similarity
messages: Belongs to the HSP15 family.

1542390:KX01 RS00515
gene id: 1542390:KX01_RS00515
uniprot id: A0A1J0KSV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1542390:KX01 RS05990
gene id: 1542390:KX01_RS05990
uniprot id: A0A1J0KW53
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1542390:KX01 RS00095
gene id: 1542390:KX01_RS00095
uniprot id: A0A1J0KSY4
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1542390:KX01 RS06565
gene id: 1542390:KX01_RS06565
uniprot id: A0A1J0KRY6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1542390:KX01 RS07480
gene id: 1542390:KX01_RS07480
uniprot id: A0A1J0KU29
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1542390:KX01 RS08940
gene id: 1542390:KX01_RS08940
uniprot id: A0A1J0KST0
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS06775
gene id: 1542390:KX01_RS06775
uniprot id: A0A1J0KS23
names: Similarity
messages: Belongs to the peptidase C59 family.

1542390:KX01 RS03375
gene id: 1542390:KX01_RS03375
uniprot id: A0A1J0KUS7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1542390:KX01 RS04885
gene id: 1542390:KX01_RS04885
uniprot id: A0A1J0KRK9
names: Similarity
messages: Belongs to the RecJ family.

1542390:KX01 RS03895
gene id: 1542390:KX01_RS03895
uniprot id: A0A1J0KU64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1542390:KX01 RS03845
gene id: 1542390:KX01_RS03845
uniprot id: A0A1J0KR75
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1542390:KX01 RS01930
gene id: 1542390:KX01_RS01930
uniprot id: A0A1J0KVU3
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1542390:KX01 RS08185
gene id: 1542390:KX01_RS08185
uniprot id: A0A1J0KTC8
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.

1542390:KX01 RS07660
gene id: 1542390:KX01_RS07660
uniprot id: A0A1J0KSK5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1542390:KX01 RS09050
gene id: 1542390:KX01_RS09050
uniprot id: A0A1J0KU27
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1542390:KX01 RS02705
gene id: 1542390:KX01_RS02705
uniprot id: A0A1J0KUG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1542390:KX01 RS03230
gene id: 1542390:KX01_RS03230
uniprot id: A0A1J0KS18
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS04775
gene id: 1542390:KX01_RS04775
uniprot id: A0A1J0KWB3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

1542390:KX01 RS06945
gene id: 1542390:KX01_RS06945
uniprot id: A0A1J0KSU0
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1542390:KX01 RS01825
gene id: 1542390:KX01_RS01825
uniprot id: A0A1J0KTR7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1542390:KX01 RS08790
gene id: 1542390:KX01_RS08790
uniprot id: A0A1J0KV39
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS06545
gene id: 1542390:KX01_RS06545
uniprot id: A0A1J0KVI3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1542390:KX01 RS05060
gene id: 1542390:KX01_RS05060
uniprot id: A0A1J0KU52
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1542390:KX01 RS04265
gene id: 1542390:KX01_RS04265
uniprot id: A0A1J0KTQ8
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS06840
gene id: 1542390:KX01_RS06840
uniprot id: A0A1J0KT06
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1542390:KX01 RS01925
gene id: 1542390:KX01_RS01925
uniprot id: A0A1J0KRF9
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1542390:KX01 RS05570
gene id: 1542390:KX01_RS05570
uniprot id: A0A1J0KU58
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1542390:KX01 RS02855
gene id: 1542390:KX01_RS02855
uniprot id: A0A1J0KUN0
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS04910
gene id: 1542390:KX01_RS04910
uniprot id: A0A1J0KTW4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1542390:KX01 RS03840
gene id: 1542390:KX01_RS03840
uniprot id: A0A1J0KV15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1542390:KX01 RS04880
gene id: 1542390:KX01_RS04880
uniprot id: A0A1J0KSW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1542390:KX01 RS03285
gene id: 1542390:KX01_RS03285
uniprot id: A0A1J0KTK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1542390:KX01 RS01900
gene id: 1542390:KX01_RS01900
uniprot id: A0A1J0KVB7
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS02110
gene id: 1542390:KX01_RS02110
uniprot id: A0A1J0KVR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1542390:KX01 RS01320
gene id: 1542390:KX01_RS01320
uniprot id: A0A1J0KS24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1542390:KX01 RS00875
gene id: 1542390:KX01_RS00875
uniprot id: A0A1J0KUI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1542390:KX01 RS07565
gene id: 1542390:KX01_RS07565
uniprot id: A0A1J0KRA3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1542390:KX01 RS01960
gene id: 1542390:KX01_RS01960
uniprot id: A0A1J0KV55
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1542390:KX01 RS03190
gene id: 1542390:KX01_RS03190
uniprot id: A0A1J0KTB5
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS00910
gene id: 1542390:KX01_RS00910
uniprot id: A0A1J0KS54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1542390:KX01 RS08350
gene id: 1542390:KX01_RS08350
uniprot id: A0A1J0KSL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1542390:KX01 RS07655
gene id: 1542390:KX01_RS07655
uniprot id: A0A1J0KUK4
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS00755
gene id: 1542390:KX01_RS00755
uniprot id: A0A1J0KUB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1542390:KX01 RS00525
gene id: 1542390:KX01_RS00525
uniprot id: A0A1J0KUS6
names: Similarity
messages: Belongs to the ArsC family.

1542390:KX01 RS07185
gene id: 1542390:KX01_RS07185
uniprot id: A0A1J0KRP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1542390:KX01 RS03135
gene id: 1542390:KX01_RS03135
uniprot id: A0A1J0KVH8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1542390:KX01 RS09035
gene id: 1542390:KX01_RS09035
uniprot id: A0A1J0KR71
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

1542390:KX01 RS09065
gene id: 1542390:KX01_RS09065
uniprot id: A0A1J0KUC8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1542390:KX01 RS03130
gene id: 1542390:KX01_RS03130
uniprot id: A0A1J0KV61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1542390:KX01 RS00075
gene id: 1542390:KX01_RS00075
uniprot id: A0A1J0KUQ3
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1542390:KX01 RS04665
gene id: 1542390:KX01_RS04665
uniprot id: A0A1J0KSP6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1542390:KX01 RS07965
gene id: 1542390:KX01_RS07965
uniprot id: A0A1J0KS19
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1542390:KX01 RS08300
gene id: 1542390:KX01_RS08300
uniprot id: A0A1J0KSU8
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1542390:KX01 RS00980
gene id: 1542390:KX01_RS00980
uniprot id: A0A1J0KSW8
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1542390:KX01 RS00820
gene id: 1542390:KX01_RS00820
uniprot id: A0A1J0KTP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1542390:KX01 RS05600
gene id: 1542390:KX01_RS05600
uniprot id: A0A1J0KS30
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1542390:KX01 RS01990
gene id: 1542390:KX01_RS01990
uniprot id: A0A1J0KTA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1542390:KX01 RS08415
gene id: 1542390:KX01_RS08415
uniprot id: A0A1J0KWG4
names: Similarity
messages: Belongs to the XseB family.

1542390:KX01 RS06495
gene id: 1542390:KX01_RS06495
uniprot id: A0A1J0KRD8
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1542390:KX01 RS07385
gene id: 1542390:KX01_RS07385
uniprot id: A0A1J0KWD8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1542390:KX01 RS01030
gene id: 1542390:KX01_RS01030
uniprot id: A0A1J0KVC0
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1542390:KX01 RS00285
gene id: 1542390:KX01_RS00285
uniprot id: A0A1J0KRH0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1542390:KX01 RS05960
gene id: 1542390:KX01_RS05960
uniprot id: A0A1J0KS36
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1542390:KX01 RS00500
gene id: 1542390:KX01_RS00500
uniprot id: A0A1J0KU33
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1542390:KX01 RS04670
gene id: 1542390:KX01_RS04670
uniprot id: A0A1J0KU30
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1542390:KX01 RS01830
gene id: 1542390:KX01_RS01830
uniprot id: A0A1J0KUQ2
names: Similarity
messages: Belongs to the citrate synthase family.

1542390:KX01 RS01365
gene id: 1542390:KX01_RS01365
uniprot id: A0A1J0KRI9
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS02300
gene id: 1542390:KX01_RS02300
uniprot id: A0A1J0KWC3
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS01265
gene id: 1542390:KX01_RS01265
uniprot id: A0A1J0KTM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1542390:KX01 RS00915
gene id: 1542390:KX01_RS00915
uniprot id: A0A1J0KV42
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1542390:KX01 RS09170
gene id: 1542390:KX01_RS09170
uniprot id: A0A1J0KTE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1542390:KX01 RS03410
gene id: 1542390:KX01_RS03410
uniprot id: A0A1J0KWC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1542390:KX01 RS06610
gene id: 1542390:KX01_RS06610
uniprot id: A0A1J0KT39
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS03880
gene id: 1542390:KX01_RS03880
uniprot id: A0A1J0KVS8
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1542390:KX01 RS01380
gene id: 1542390:KX01_RS01380
uniprot id: A0A1J0KSM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1542390:KX01 RS06880
gene id: 1542390:KX01_RS06880
uniprot id: A0A1J0KSA1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1542390:KX01 RS09095
gene id: 1542390:KX01_RS09095
uniprot id: A0A1J0KUU8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1542390:KX01 RS02140
gene id: 1542390:KX01_RS02140
uniprot id: A0A1J0KT79
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1542390:KX01 RS03255
gene id: 1542390:KX01_RS03255
uniprot id: A0A1J0KUL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1542390:KX01 RS06315
gene id: 1542390:KX01_RS06315
uniprot id: A0A1J0KSS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1542390:KX01 RS07040
gene id: 1542390:KX01_RS07040
uniprot id: A0A1J0KU98
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1542390:KX01 RS00880
gene id: 1542390:KX01_RS00880
uniprot id: A0A1J0KVY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1542390:KX01 RS07325
gene id: 1542390:KX01_RS07325
uniprot id: A0A1J0KRJ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1542390:KX01 RS07155
gene id: 1542390:KX01_RS07155
uniprot id: A0A1J0KSZ7
names: Similarity
messages: Belongs to the UPF0434 family.

1542390:KX01 RS03505
gene id: 1542390:KX01_RS03505
uniprot id: A0A1J0KT97
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1542390:KX01 RS05740
gene id: 1542390:KX01_RS05740
uniprot id: A0A1J0KU18
names: Similarity
messages: Belongs to the DEAD box helicase family.

1542390:KX01 RS00780
gene id: 1542390:KX01_RS00780
uniprot id: A0A1J0KT34
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1542390:KX01 RS03515
gene id: 1542390:KX01_RS03515
uniprot id: A0A1J0KTS9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1542390:KX01 RS03050
gene id: 1542390:KX01_RS03050
uniprot id: A0A1J0KTQ6
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS00290
gene id: 1542390:KX01_RS00290
uniprot id: A0A1J0KU84
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS00465
gene id: 1542390:KX01_RS00465
uniprot id: A0A1J0KTT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1542390:KX01 RS09145
gene id: 1542390:KX01_RS09145
uniprot id: A0A1J0KT59
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1542390:KX01 RS01815
gene id: 1542390:KX01_RS01815
uniprot id: A0A1J0KTY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1542390:KX01 RS00815
gene id: 1542390:KX01_RS00815
uniprot id: A0A1J0KUU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1542390:KX01 RS03080
gene id: 1542390:KX01_RS03080
uniprot id: A0A1J0KUP1
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1542390:KX01 RS04940
gene id: 1542390:KX01_RS04940
uniprot id: A0A1J0KTW8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1542390:KX01 RS05785
gene id: 1542390:KX01_RS05785
uniprot id: A0A1J0KSI0
names: Similarity
messages: Belongs to the peptidase S51 family.

1542390:KX01 RS04970
gene id: 1542390:KX01_RS04970
uniprot id: A0A1J0KWJ2
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

1542390:KX01 RS01195
gene id: 1542390:KX01_RS01195
uniprot id: A0A1J0KV98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1542390:KX01 RS07005
gene id: 1542390:KX01_RS07005
uniprot id: A0A1J0KU57
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1542390:KX01 RS01210
gene id: 1542390:KX01_RS01210
uniprot id: A0A1J0KTN3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1542390:KX01 RS05530
gene id: 1542390:KX01_RS05530
uniprot id: A0A1J0KV71
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS05110
gene id: 1542390:KX01_RS05110
uniprot id: A0A1J0KWH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1542390:KX01 RS05030
gene id: 1542390:KX01_RS05030
uniprot id: A0A1J0KW89
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

1542390:KX01 RS02105
gene id: 1542390:KX01_RS02105
uniprot id: A0A1J0KV07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1542390:KX01 RS00795
gene id: 1542390:KX01_RS00795
uniprot id: A0A1J0KW14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1542390:KX01 RS04995
gene id: 1542390:KX01_RS04995
uniprot id: A0A1J0KS13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1542390:KX01 RS05820
gene id: 1542390:KX01_RS05820
uniprot id: A0A1J0KTT5
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1542390:KX01 RS07770
gene id: 1542390:KX01_RS07770
uniprot id: A0A1J0KVJ3
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1542390:KX01 RS08375
gene id: 1542390:KX01_RS08375
uniprot id: A0A1J0KVZ6
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1542390:KX01 RS05720
gene id: 1542390:KX01_RS05720
uniprot id: A0A1J0KTR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1542390:KX01 RS07610
gene id: 1542390:KX01_RS07610
uniprot id: A0A1J0KRX6
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1542390:KX01 RS01170
gene id: 1542390:KX01_RS01170
uniprot id: A0A1J0KU38
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

1542390:KX01 RS08890
gene id: 1542390:KX01_RS08890
uniprot id: A0A1J0KVP5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1542390:KX01 RS04650
gene id: 1542390:KX01_RS04650
uniprot id: A0A1J0KUU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1542390:KX01 RS05360
gene id: 1542390:KX01_RS05360
uniprot id: A0A1J0KT24
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1542390:KX01 RS03290
gene id: 1542390:KX01_RS03290
uniprot id: A0A1J0KTY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1542390:KX01 RS07265
gene id: 1542390:KX01_RS07265
uniprot id: A0A1J0KS45
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1542390:KX01 RS06135
gene id: 1542390:KX01_RS06135
uniprot id: A0A1J0KSY9
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1542390:KX01 RS06850
gene id: 1542390:KX01_RS06850
uniprot id: A0A1J0KV68
names: Subcellular Location Annotation
messages: Cytoplasm

1542390:KX01 RS01110
gene id: 1542390:KX01_RS01110
uniprot id: A0A1J0KUS8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1542390:KX01 RS03725
gene id: 1542390:KX01_RS03725
uniprot id: A0A1J0KTZ9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1542390:KX01 RS04450
gene id: 1542390:KX01_RS04450
uniprot id: A0A1J0KTE8
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS02810
gene id: 1542390:KX01_RS02810
uniprot id: A0A1J0KRH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1542390:KX01 RS01880
gene id: 1542390:KX01_RS01880
uniprot id: A0A1J0KU83
names: Similarity
messages: Belongs to the UPF0111 family.

1542390:KX01 RS06300
gene id: 1542390:KX01_RS06300
uniprot id: A0A1J0KRF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1542390:KX01 RS05420
gene id: 1542390:KX01_RS05420
uniprot id: A0A1J0KSJ6
names: Similarity
messages: Belongs to the TPP enzyme family.

1542390:KX01 RS08235
gene id: 1542390:KX01_RS08235
uniprot id: A0A1J0KVW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1542390:KX01 RS07425
gene id: 1542390:KX01_RS07425
uniprot id: A0A1J0KT29
names: Similarity
messages: Belongs to the transposase 7 family.

1542390:KX01 RS04290
gene id: 1542390:KX01_RS04290
uniprot id: A0A1J0KRD5
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1542390:KX01 RS07885
gene id: 1542390:KX01_RS07885
uniprot id: A0A1J0KVY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1542390:KX01 RS05950
gene id: 1542390:KX01_RS05950
uniprot id: A0A1J0KSS0
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1542390:KX01 RS07065
gene id: 1542390:KX01_RS07065
uniprot id: A0A1J0KUC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1542390:KX01 RS09205
gene id: 1542390:KX01_RS09205
uniprot id: A0A1J0KTH6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1542390:KX01 RS08080
gene id: 1542390:KX01_RS08080
uniprot id: A0A1J0KVA0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1542390:KX01 RS06320
gene id: 1542390:KX01_RS06320
uniprot id: A0A1J0KUB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

1542390:KX01 RS04320
gene id: 1542390:KX01_RS04320
uniprot id: A0A1J0KU76
names: Similarity
messages: Belongs to the RutC family.

1542390:KX01 RS06960
gene id: 1542390:KX01_RS06960
uniprot id: A0A1J0KRW6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1542390:KX01 RS05335
gene id: 1542390:KX01_RS05335
uniprot id: A0A1J0KSL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1542390:KX01 RS07575
gene id: 1542390:KX01_RS07575
uniprot id: A0A1J0KSA7
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1542390:KX01 RS04870
gene id: 1542390:KX01_RS04870
uniprot id: A0A1J0KW52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1542390:KX01 RS02845
gene id: 1542390:KX01_RS02845
uniprot id: A0A1J0KVE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1542390:KX01 RS00825
gene id: 1542390:KX01_RS00825
uniprot id: A0A1J0KUZ5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1542390:KX01 RS06650
gene id: 1542390:KX01_RS06650
uniprot id: A0A1J0KTE1
names: Subunit
messages: Monomer.

1542390:KX01 RS03535
gene id: 1542390:KX01_RS03535
uniprot id: A0A1J0KRQ3
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS01550
gene id: 1542390:KX01_RS01550
uniprot id: A0A1J0KR85
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS04005
gene id: 1542390:KX01_RS04005
uniprot id: A0A1J0KS26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1542390:KX01 RS03380
gene id: 1542390:KX01_RS03380
uniprot id: A0A1J0KS59
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1542390:KX01 RS08120
gene id: 1542390:KX01_RS08120
uniprot id: A0A1J0KW16
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1542390:KX01 RS08355
gene id: 1542390:KX01_RS08355
uniprot id: A0A1J0KW40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1542390:KX01 RS00940
gene id: 1542390:KX01_RS00940
uniprot id: A0A1J0KW15
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1542390:KX01 RS04715
gene id: 1542390:KX01_RS04715
uniprot id: A0A1J0KW26
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1542390:KX01 RS08550
gene id: 1542390:KX01_RS08550
uniprot id: A0A1J0KRM7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1542390:KX01 RS04730
gene id: 1542390:KX01_RS04730
uniprot id: A0A1J0KW07
names: Similarity
messages: Belongs to the fabD family.

1542390:KX01 RS07225
gene id: 1542390:KX01_RS07225
uniprot id: A0A1J0KRL6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1542390:KX01 RS03605
gene id: 1542390:KX01_RS03605
uniprot id: A0A1J0KRU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1542390:KX01 RS04745
gene id: 1542390:KX01_RS04745
uniprot id: A0A1J0KT70
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1542390:KX01 RS02325
gene id: 1542390:KX01_RS02325
uniprot id: A0A1J0KVS4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1542390:KX01 RS02960
gene id: 1542390:KX01_RS02960
uniprot id: A0A1J0KUU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1542390:KX01 RS07940
gene id: 1542390:KX01_RS07940
uniprot id: A0A1J0KTM2
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS07180
gene id: 1542390:KX01_RS07180
uniprot id: A0A1J0KTU3
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1542390:KX01 RS05235
gene id: 1542390:KX01_RS05235
uniprot id: A0A1J0KSH2
names: Similarity
messages: Belongs to the PhoH family.

1542390:KX01 RS03095
gene id: 1542390:KX01_RS03095
uniprot id: A0A1J0KTM8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1542390:KX01 RS05005
gene id: 1542390:KX01_RS05005
uniprot id: A0A1J0KTF7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1542390:KX01 RS02090
gene id: 1542390:KX01_RS02090
uniprot id: A0A1J0KT19
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

1542390:KX01 RS07070
gene id: 1542390:KX01_RS07070
uniprot id: A0A1J0KTS0
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1542390:KX01 RS02570
gene id: 1542390:KX01_RS02570
uniprot id: A0A1J0KTT8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1542390:KX01 RS03680
gene id: 1542390:KX01_RS03680
uniprot id: A0A1J0KTK6
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS01715
gene id: 1542390:KX01_RS01715
uniprot id: A0A1J0KV40
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

1542390:KX01 RS05605
gene id: 1542390:KX01_RS05605
uniprot id: A0A1J0KSW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1542390:KX01 RS07830
gene id: 1542390:KX01_RS07830
uniprot id: A0A1J0KUN4
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

1542390:KX01 RS07780
gene id: 1542390:KX01_RS07780
uniprot id: A0A1J0KSG9
names: Similarity
messages: Belongs to the peptidase C59 family.

1542390:KX01 RS00775
gene id: 1542390:KX01_RS00775
uniprot id: A0A1J0KS50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1542390:KX01 RS02345
gene id: 1542390:KX01_RS02345
uniprot id: A0A1J0KV67
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS06330
gene id: 1542390:KX01_RS06330
uniprot id: A0A1J0KVG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1542390:KX01 RS00105
gene id: 1542390:KX01_RS00105
uniprot id: A0A1J0KTY0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1542390:KX01 RS04915
gene id: 1542390:KX01_RS04915
uniprot id: A0A1J0KV74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1542390:KX01 RS02025
gene id: 1542390:KX01_RS02025
uniprot id: A0A1J0KUJ4
names: Similarity
messages: Belongs to the Skp family.

1542390:KX01 RS02865
gene id: 1542390:KX01_RS02865
uniprot id: A0A1J0KVP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1542390:KX01 RS09125
gene id: 1542390:KX01_RS09125
uniprot id: A0A1J0KVC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1542390:KX01 RS08525
gene id: 1542390:KX01_RS08525
uniprot id: A0A1J0KUA0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1542390:KX01 RS06220
gene id: 1542390:KX01_RS06220
uniprot id: A0A1J0KVF4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1542390:KX01 RS03465
gene id: 1542390:KX01_RS03465
uniprot id: A0A1J0KUM3
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS01360
gene id: 1542390:KX01_RS01360
uniprot id: A0A1J0KS29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1542390:KX01 RS03580
gene id: 1542390:KX01_RS03580
uniprot id: A0A1J0KVS9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1542390:KX01 RS03830
gene id: 1542390:KX01_RS03830
uniprot id: A0A1J0KTZ1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1542390:KX01 RS06145
gene id: 1542390:KX01_RS06145
uniprot id: A0A1J0KTC9
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1542390:KX01 RS05435
gene id: 1542390:KX01_RS05435
uniprot id: A0A1J0KUA2
names: Similarity
messages: Belongs to the glyoxalase I family.

1542390:KX01 RS00255
gene id: 1542390:KX01_RS00255
uniprot id: A0A1J0KS33
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1542390:KX01 RS07900
gene id: 1542390:KX01_RS07900
uniprot id: A0A1J0KUH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1542390:KX01 RS06270
gene id: 1542390:KX01_RS06270
uniprot id: A0A1J0KRA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

1542390:KX01 RS04765
gene id: 1542390:KX01_RS04765
uniprot id: A0A1J0KVH4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1542390:KX01 RS00840
gene id: 1542390:KX01_RS00840
uniprot id: A0A1J0KVM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1542390:KX01 RS08165
gene id: 1542390:KX01_RS08165
uniprot id: A0A1J0KU75
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1542390:KX01 RS08880
gene id: 1542390:KX01_RS08880
uniprot id: A0A1J0KVT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

1542390:KX01 RS06090
gene id: 1542390:KX01_RS06090
uniprot id: A0A1J0KS48
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1542390:KX01 RS07295
gene id: 1542390:KX01_RS07295
uniprot id: A0A1J0KVL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1542390:KX01 RS03105
gene id: 1542390:KX01_RS03105
uniprot id: A0A1J0KU68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1542390:KX01 RS05405
gene id: 1542390:KX01_RS05405
uniprot id: A0A1J0KUY2
names: Similarity
messages: Belongs to the DEAD box helicase family.

1542390:KX01 RS01740
gene id: 1542390:KX01_RS01740
uniprot id: A0A1J0KRB5
names: Similarity
messages: Belongs to the HypD family.

1542390:KX01 RS02440
gene id: 1542390:KX01_RS02440
uniprot id: A0A1J0KSC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1542390:KX01 RS08440
gene id: 1542390:KX01_RS08440
uniprot id: A0A1J0KTJ2
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1542390:KX01 RS05015
gene id: 1542390:KX01_RS05015
uniprot id: A0A1J0KTQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1542390:KX01 RS03915
gene id: 1542390:KX01_RS03915
uniprot id: A0A1J0KRW7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1542390:KX01 RS03395
gene id: 1542390:KX01_RS03395
uniprot id: A0A1J0KUX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Membrane

1542390:KX01 RS05395
gene id: 1542390:KX01_RS05395
uniprot id: A0A1J0KRE7
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1542390:KX01 RS02665
gene id: 1542390:KX01_RS02665
uniprot id: A0A1J0KTC1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1542390:KX01 RS08910
gene id: 1542390:KX01_RS08910
uniprot id: A0A1J0KUG1
names: Similarity
messages: Belongs to the HesB/IscA family.

1542390:KX01 RS02980
gene id: 1542390:KX01_RS02980
uniprot id: A0A1J0KSU6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

1542390:KX01 RS08460
gene id: 1542390:KX01_RS08460
uniprot id: A0A1J0KRE5
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

1542390:KX01 RS06980
gene id: 1542390:KX01_RS06980
uniprot id: A0A1J0KTA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1542390:KX01 RS02890
gene id: 1542390:KX01_RS02890
uniprot id: A0A1J0KSD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1542390:KX01 RS08670
gene id: 1542390:KX01_RS08670
uniprot id: A0A1J0KSS2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1542390:KX01 RS00110
gene id: 1542390:KX01_RS00110
uniprot id: A0A1J0KSB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1542390:KX01 RS01405
gene id: 1542390:KX01_RS01405
uniprot id: A0A1J0KRK2
names: Similarity
messages: Belongs to the YggT family.

1542390:KX01 RS02200
gene id: 1542390:KX01_RS02200
uniprot id: A0A1J0KRS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1542390:KX01 RS00025
gene id: 1542390:KX01_RS00025
uniprot id: A0A1J0KV64
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1542390:KX01 RS04465
gene id: 1542390:KX01_RS04465
uniprot id: A0A1J0KSZ4
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1542390:KX01 RS07725
gene id: 1542390:KX01_RS07725
uniprot id: A0A1J0KRG8
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

1542390:KX01 RS00740
gene id: 1542390:KX01_RS00740
uniprot id: A0A1J0KVY1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1542390:KX01 RS04390
gene id: 1542390:KX01_RS04390
uniprot id: A0A1J0KUA8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1542390:KX01 RS07670
gene id: 1542390:KX01_RS07670
uniprot id: A0A1J0KTW9
names: Similarity
messages: Belongs to the peptidase C59 family.

1542390:KX01 RS07515
gene id: 1542390:KX01_RS07515
uniprot id: A0A1J0KRX1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1542390:KX01 RS08290
gene id: 1542390:KX01_RS08290
uniprot id: A0A1J0KSH8
names: Similarity
messages: Belongs to the peptidase S13 family.

1542390:KX01 RS06325
gene id: 1542390:KX01_RS06325
uniprot id: A0A1J0KRD0
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS01535
gene id: 1542390:KX01_RS01535
uniprot id: A0A1J0KV66
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS06910
gene id: 1542390:KX01_RS06910
uniprot id: A0A1J0KVE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

1542390:KX01 RS00745
gene id: 1542390:KX01_RS00745
uniprot id: A0A1J0KTS2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1542390:KX01 RS08200
gene id: 1542390:KX01_RS08200
uniprot id: A0A1J0KUK7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1542390:KX01 RS06510
gene id: 1542390:KX01_RS06510
uniprot id: A0A1J0KSQ5
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS01285
gene id: 1542390:KX01_RS01285
uniprot id: A0A1J0KTR5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1542390:KX01 RS00205
gene id: 1542390:KX01_RS00205
uniprot id: A0A1J0KTF6
names: Similarity
messages: Belongs to the UPF0102 family.

1542390:KX01 RS06035
gene id: 1542390:KX01_RS06035
uniprot id: A0A1J0KU37
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1542390:KX01 RS03480
gene id: 1542390:KX01_RS03480
uniprot id: A0A1J0KUH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

1542390:KX01 RS00700
gene id: 1542390:KX01_RS00700
uniprot id: A0A1J0KSA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1542390:KX01 RS00340
gene id: 1542390:KX01_RS00340
uniprot id: A0A1J0KV38
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1542390:KX01 RS00565
gene id: 1542390:KX01_RS00565
uniprot id: A0A1J0KRQ8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1542390:KX01 RS02190
gene id: 1542390:KX01_RS02190
uniprot id: A0A1J0KVR5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1542390:KX01 RS00960
gene id: 1542390:KX01_RS00960
uniprot id: A0A1J0KTR3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1542390:KX01 RS01875
gene id: 1542390:KX01_RS01875
uniprot id: A0A1J0KVY7
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS03000
gene id: 1542390:KX01_RS03000
uniprot id: A0A1J0KTW1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

1542390:KX01 RS03155
gene id: 1542390:KX01_RS03155
uniprot id: A0A1J0KSL8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1542390:KX01 RS04440
gene id: 1542390:KX01_RS04440
uniprot id: A0A1J0KT08
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1542390:KX01 RS03225
gene id: 1542390:KX01_RS03225
uniprot id: A0A1J0KUP7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1542390:KX01 RS03075
gene id: 1542390:KX01_RS03075
uniprot id: A0A1J0KTD2
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS07475
gene id: 1542390:KX01_RS07475
uniprot id: A0A1J0KUQ6
names: Similarity
messages: Belongs to the peptidase M24B family.

1542390:KX01 RS06905
gene id: 1542390:KX01_RS06905
uniprot id: A0A1J0KUF7
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS08170
gene id: 1542390:KX01_RS08170
uniprot id: A0A1J0KSL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1542390:KX01 RS08875
gene id: 1542390:KX01_RS08875
uniprot id: A0A1J0KWE2
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS06805
gene id: 1542390:KX01_RS06805
uniprot id: A0A1J0KVA3
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

1542390:KX01 RS03475
gene id: 1542390:KX01_RS03475
uniprot id: A0A1J0KVE2
names: Similarity
messages: Belongs to the FBPase class 2 family.

1542390:KX01 RS05430
gene id: 1542390:KX01_RS05430
uniprot id: A0A1J0KSP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1542390:KX01 RS01225
gene id: 1542390:KX01_RS01225
uniprot id: A0A1J0KTB0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1542390:KX01 RS04425
gene id: 1542390:KX01_RS04425
uniprot id: A0A1J0KSL6
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1542390:KX01 RS00395
gene id: 1542390:KX01_RS00395
uniprot id: A0A1J0KST7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1542390:KX01 RS08510
gene id: 1542390:KX01_RS08510
uniprot id: A0A1J0KTD1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1542390:KX01 RS04680
gene id: 1542390:KX01_RS04680
uniprot id: A0A1J0KUI5
names: Similarity
messages: Belongs to the YciI family.

1542390:KX01 RS02975
gene id: 1542390:KX01_RS02975
uniprot id: A0A1J0KUT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1542390:KX01 RS02925
gene id: 1542390:KX01_RS02925
uniprot id: A0A1J0KT72
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1542390:KX01 RS05025
gene id: 1542390:KX01_RS05025
uniprot id: A0A1J0KSV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

1542390:KX01 RS06240
gene id: 1542390:KX01_RS06240
uniprot id: A0A1J0KS76
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1542390:KX01 RS05325
gene id: 1542390:KX01_RS05325
uniprot id: A0A1J0KVK9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1542390:KX01 RS00615
gene id: 1542390:KX01_RS00615
uniprot id: A0A1J0KT74
names: Similarity
messages: Belongs to the BolA/IbaG family.

1542390:KX01 RS07455
gene id: 1542390:KX01_RS07455
uniprot id: A0A1J0KRH1
names: Similarity
messages: Belongs to the peptidase C59 family.

1542390:KX01 RS04010
gene id: 1542390:KX01_RS04010
uniprot id: A0A1J0KW64
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1542390:KX01 RS04310
gene id: 1542390:KX01_RS04310
uniprot id: A0A1J0KT28
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS01600
gene id: 1542390:KX01_RS01600
uniprot id: A0A1J0KTH2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1542390:KX01 RS01100
gene id: 1542390:KX01_RS01100
uniprot id: A0A1J0KW19
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1542390:KX01 RS04720
gene id: 1542390:KX01_RS04720
uniprot id: A0A1J0KRI3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1542390:KX01 RS00250
gene id: 1542390:KX01_RS00250
uniprot id: A0A1J0KT57
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1542390:KX01 RS00890
gene id: 1542390:KX01_RS00890
uniprot id: A0A1J0KUS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1542390:KX01 RS05805
gene id: 1542390:KX01_RS05805
uniprot id: A0A1J0KTN5
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS08770
gene id: 1542390:KX01_RS08770
uniprot id: A0A1J0KRA1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1542390:KX01 RS07530
gene id: 1542390:KX01_RS07530
uniprot id: A0A1J0KS84
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

1542390:KX01 RS06150
gene id: 1542390:KX01_RS06150
uniprot id: A0A1J0KV52
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1542390:KX01 RS07890
gene id: 1542390:KX01_RS07890
uniprot id: A0A1J0KRJ3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1542390:KX01 RS08190
gene id: 1542390:KX01_RS08190
uniprot id: A0A1J0KU44
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1542390:KX01 RS06490
gene id: 1542390:KX01_RS06490
uniprot id: A0A1J0KUJ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1542390:KX01 RS00710
gene id: 1542390:KX01_RS00710
uniprot id: A0A1J0KVU2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1542390:KX01 RS06310
gene id: 1542390:KX01_RS06310
uniprot id: A0A1J0KTQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1542390:KX01 RS08755
gene id: 1542390:KX01_RS08755
uniprot id: A0A1J0KU86
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1542390:KX01 RS08855
gene id: 1542390:KX01_RS08855
uniprot id: A0A1J0KVV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1542390:KX01 RS06080
gene id: 1542390:KX01_RS06080
uniprot id: A0A1J0KSC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1542390:KX01 RS07145
gene id: 1542390:KX01_RS07145
uniprot id: A0A1J0KRM8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1542390:KX01 RS09030
gene id: 1542390:KX01_RS09030
uniprot id: A0A1J0KSS7
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

1542390:KX01 RS02445
gene id: 1542390:KX01_RS02445
uniprot id: A0A1J0KW81
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1542390:KX01 RS00435
gene id: 1542390:KX01_RS00435
uniprot id: A0A1J0KR99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1542390:KX01 RS03355
gene id: 1542390:KX01_RS03355
uniprot id: A0A1J0KT22
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1542390:KX01 RS01465
gene id: 1542390:KX01_RS01465
uniprot id: A0A1J0KRK5
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1542390:KX01 RS01795
gene id: 1542390:KX01_RS01795
uniprot id: A0A1J0KTN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1542390:KX01 RS02965
gene id: 1542390:KX01_RS02965
uniprot id: A0A1J0KRB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1542390:KX01 RS02425
gene id: 1542390:KX01_RS02425
uniprot id: A0A1J0KVI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1542390:KX01 RS00835
gene id: 1542390:KX01_RS00835
uniprot id: A0A1J0KTY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1542390:KX01 RS07680
gene id: 1542390:KX01_RS07680
uniprot id: A0A1J0KRD1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1542390:KX01 RS06780
gene id: 1542390:KX01_RS06780
uniprot id: A0A1J0KRI8
names: Subcellular Location Annotation
messages: Cytoplasm

1542390:KX01 RS00785
gene id: 1542390:KX01_RS00785
uniprot id: A0A1J0KRB4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1542390:KX01 RS02600
gene id: 1542390:KX01_RS02600
uniprot id: A0A1J0KSL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1542390:KX01 RS07415
gene id: 1542390:KX01_RS07415
uniprot id: A0A1J0KVN6
names: Similarity
messages: Belongs to the FrmR/RcnR family.

1542390:KX01 RS07950
gene id: 1542390:KX01_RS07950
uniprot id: A0A1J0KVP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1542390:KX01 RS08850
gene id: 1542390:KX01_RS08850
uniprot id: A0A1J0KTV6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1542390:KX01 RS03715
gene id: 1542390:KX01_RS03715
uniprot id: A0A1J0KRA2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

1542390:KX01 RS03030
gene id: 1542390:KX01_RS03030
uniprot id: A0A1J0KRG4
names: Similarity
messages: Belongs to the GSP E family.

1542390:KX01 RS06605
gene id: 1542390:KX01_RS06605
uniprot id: A0A1J0KSN7
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS00485
gene id: 1542390:KX01_RS00485
uniprot id: A0A1J0KTZ0
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1542390:KX01 RS02195
gene id: 1542390:KX01_RS02195
uniprot id: A0A1J0KT89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1542390:KX01 RS03640
gene id: 1542390:KX01_RS03640
uniprot id: A0A1J0KSR7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1542390:KX01 RS07775
gene id: 1542390:KX01_RS07775
uniprot id: A0A1J0KRT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1542390:KX01 RS00125
gene id: 1542390:KX01_RS00125
uniprot id: A0A1J0KSI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1542390:KX01 RS06280
gene id: 1542390:KX01_RS06280
uniprot id: A0A1J0KS87
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

1542390:KX01 RS08430
gene id: 1542390:KX01_RS08430
uniprot id: A0A1J0KVF2
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS07380
gene id: 1542390:KX01_RS07380
uniprot id: A0A1J0KWD3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1542390:KX01 RS01515
gene id: 1542390:KX01_RS01515
uniprot id: A0A1J0KV30
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS00970
gene id: 1542390:KX01_RS00970
uniprot id: A0A1J0KTN1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1542390:KX01 RS03365
gene id: 1542390:KX01_RS03365
uniprot id: A0A1J0KUV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1542390:KX01 RS08915
gene id: 1542390:KX01_RS08915
uniprot id: A0A1J0KU45
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1542390:KX01 RS07850
gene id: 1542390:KX01_RS07850
uniprot id: A0A1J0KTN7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1542390:KX01 RS03455
gene id: 1542390:KX01_RS03455
uniprot id: A0A1J0KWH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1542390:KX01 RS01215
gene id: 1542390:KX01_RS01215
uniprot id: A0A1J0KRQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1542390:KX01 RS07310
gene id: 1542390:KX01_RS07310
uniprot id: A0A1J0KSM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1542390:KX01 RS04400
gene id: 1542390:KX01_RS04400
uniprot id: A0A1J0KU88
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

1542390:KX01 RS02910
gene id: 1542390:KX01_RS02910
uniprot id: A0A1J0KR87
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1542390:KX01 RS05370
gene id: 1542390:KX01_RS05370
uniprot id: A0A1J0KRD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1542390:KX01 RS08585
gene id: 1542390:KX01_RS08585
uniprot id: A0A1J0KRZ4
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1542390:KX01 RS03170
gene id: 1542390:KX01_RS03170
uniprot id: A0A1J0KVE3
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS06800
gene id: 1542390:KX01_RS06800
uniprot id: A0A1J0KR92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1542390:KX01 RS06085
gene id: 1542390:KX01_RS06085
uniprot id: A0A1J0KUX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1542390:KX01 RS01460
gene id: 1542390:KX01_RS01460
uniprot id: A0A1J0KRD4
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1542390:KX01 RS02805
gene id: 1542390:KX01_RS02805
uniprot id: A0A1J0KUH1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1542390:KX01 RS03405
gene id: 1542390:KX01_RS03405
uniprot id: A0A1J0KS95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1542390:KX01 RS06475
gene id: 1542390:KX01_RS06475
uniprot id: A0A1J0KVF1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1542390:KX01 RS01190
gene id: 1542390:KX01_RS01190
uniprot id: A0A1J0KTA3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1542390:KX01 RS00930
gene id: 1542390:KX01_RS00930
uniprot id: A0A1J0KVL9
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1542390:KX01 RS03415
gene id: 1542390:KX01_RS03415
uniprot id: A0A1J0KV49
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1542390:KX01 RS09105
gene id: 1542390:KX01_RS09105
uniprot id: A0A1J0KVG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1542390:KX01 RS00390
gene id: 1542390:KX01_RS00390
uniprot id: A0A1J0KUJ3
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1542390:KX01 RS03990
gene id: 1542390:KX01_RS03990
uniprot id: A0A1J0KUN3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

1542390:KX01 RS03060
gene id: 1542390:KX01_RS03060
uniprot id: A0A1J0KRX2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1542390:KX01 RS02670
gene id: 1542390:KX01_RS02670
uniprot id: A0A1J0KWF1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1542390:KX01 RS01800
gene id: 1542390:KX01_RS01800
uniprot id: A0A1J0KRI1
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1542390:KX01 RS04865
gene id: 1542390:KX01_RS04865
uniprot id: A0A1J0KUD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1542390:KX01 RS05065
gene id: 1542390:KX01_RS05065
uniprot id: A0A1J0KUW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1542390:KX01 RS09110
gene id: 1542390:KX01_RS09110
uniprot id: A0A1J0KSN2
names: Similarity
messages: Belongs to the peptidase M16 family.

1542390:KX01 RS00175
gene id: 1542390:KX01_RS00175
uniprot id: A0A1J0KUM4
names: Similarity
messages: Belongs to the GARS family.
messages: Belongs to the SAICAR synthetase family.

1542390:KX01 RS03115
gene id: 1542390:KX01_RS03115
uniprot id: A0A1J0KS02
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1542390:KX01 RS05565
gene id: 1542390:KX01_RS05565
uniprot id: A0A1J0KV93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

1542390:KX01 RS08125
gene id: 1542390:KX01_RS08125
uniprot id: A0A1J0KR58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1542390:KX01 RS06885
gene id: 1542390:KX01_RS06885
uniprot id: A0A1J0KVK7
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1542390:KX01 RS06755
gene id: 1542390:KX01_RS06755
uniprot id: A0A1J0KT12
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1542390:KX01 RS03540
gene id: 1542390:KX01_RS03540
uniprot id: A0A1J0KVC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1542390:KX01 RS08985
gene id: 1542390:KX01_RS08985
uniprot id: A0A1J0KR64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1542390:KX01 RS00260
gene id: 1542390:KX01_RS00260
uniprot id: A0A1J0KU22
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1542390:KX01 RS05410
gene id: 1542390:KX01_RS05410
uniprot id: A0A1J0KV26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1542390:KX01 RS03010
gene id: 1542390:KX01_RS03010
uniprot id: A0A1J0KVW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1542390:KX01 RS00300
gene id: 1542390:KX01_RS00300
uniprot id: A0A1J0KUM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1542390:KX01 RS04810
gene id: 1542390:KX01_RS04810
uniprot id: A0A1J0KUU0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1542390:KX01 RS07970
gene id: 1542390:KX01_RS07970
uniprot id: A0A1J0KS31
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1542390:KX01 RS04280
gene id: 1542390:KX01_RS04280
uniprot id: A0A1J0KRY1
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS02620
gene id: 1542390:KX01_RS02620
uniprot id: A0A1J0KVF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1542390:KX01 RS04735
gene id: 1542390:KX01_RS04735
uniprot id: A0A1J0KVX8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1542390:KX01 RS08975
gene id: 1542390:KX01_RS08975
uniprot id: A0A1J0KR82
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

1542390:KX01 RS05130
gene id: 1542390:KX01_RS05130
uniprot id: A0A1J0KT99
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1542390:KX01 RS01165
gene id: 1542390:KX01_RS01165
uniprot id: A0A1J0KW59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1542390:KX01 RS06180
gene id: 1542390:KX01_RS06180
uniprot id: A0A1J0KU48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1542390:KX01 RS02835
gene id: 1542390:KX01_RS02835
uniprot id: A0A1J0KU82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1542390:KX01 RS03200
gene id: 1542390:KX01_RS03200
uniprot id: A0A1J0KRN2
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS00660
gene id: 1542390:KX01_RS00660
uniprot id: A0A1J0KSH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1542390:KX01 RS05665
gene id: 1542390:KX01_RS05665
uniprot id: A0A1J0KVF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1542390:KX01 RS09055
gene id: 1542390:KX01_RS09055
uniprot id: A0A1J0KR96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1542390:KX01 RS01010
gene id: 1542390:KX01_RS01010
uniprot id: A0A1J0KSQ7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1542390:KX01 RS09180
gene id: 1542390:KX01_RS09180
uniprot id: A0A1J0KVW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1542390:KX01 RS04040
gene id: 1542390:KX01_RS04040
uniprot id: A0A1J0KTQ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1542390:KX01 RS02950
gene id: 1542390:KX01_RS02950
uniprot id: A0A1J0KTB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1542390:KX01 RS04740
gene id: 1542390:KX01_RS04740
uniprot id: A0A1J0KVG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1542390:KX01 RS02685
gene id: 1542390:KX01_RS02685
uniprot id: A0A1J0KVC6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

1542390:KX01 RS08835
gene id: 1542390:KX01_RS08835
uniprot id: A0A1J0KRQ7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1542390:KX01 RS07010
gene id: 1542390:KX01_RS07010
uniprot id: A0A1J0KV37
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS03765
gene id: 1542390:KX01_RS03765
uniprot id: A0A1J0KU31
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1542390:KX01 RS03645
gene id: 1542390:KX01_RS03645
uniprot id: A0A1J0KVZ7
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1542390:KX01 RS09100
gene id: 1542390:KX01_RS09100
uniprot id: A0A1J0KUZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1542390:KX01 RS00190
gene id: 1542390:KX01_RS00190
uniprot id: A0A1J0KS21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1542390:KX01 RS00570
gene id: 1542390:KX01_RS00570
uniprot id: A0A1J0KRM2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1542390:KX01 RS08580
gene id: 1542390:KX01_RS08580
uniprot id: A0A1J0KWC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1542390:KX01 RS00655
gene id: 1542390:KX01_RS00655
uniprot id: A0A1J0KW18
names: Similarity
messages: Belongs to the YfgM family.

1542390:KX01 RS00625
gene id: 1542390:KX01_RS00625
uniprot id: A0A1J0KSF8
names: Similarity
messages: Belongs to the MlaA family.

1542390:KX01 RS06175
gene id: 1542390:KX01_RS06175
uniprot id: A0A1J0KRN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1542390:KX01 RS03335
gene id: 1542390:KX01_RS03335
uniprot id: A0A1J0KSL7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1542390:KX01 RS03210
gene id: 1542390:KX01_RS03210
uniprot id: A0A1J0KSE1
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1542390:KX01 RS05220
gene id: 1542390:KX01_RS05220
uniprot id: A0A1J0KTC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1542390:KX01 RS08395
gene id: 1542390:KX01_RS08395
uniprot id: A0A1J0KRR1
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS02750
gene id: 1542390:KX01_RS02750
uniprot id: A0A1J0KRM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

1542390:KX01 RS07150
gene id: 1542390:KX01_RS07150
uniprot id: A0A1J0KT93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1542390:KX01 RS06810
gene id: 1542390:KX01_RS06810
uniprot id: A0A1J0KSH0
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1542390:KX01 RS03015
gene id: 1542390:KX01_RS03015
uniprot id: A0A1J0KVA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1542390:KX01 RS00145
gene id: 1542390:KX01_RS00145
uniprot id: A0A1J0KT68
names: Similarity
messages: Belongs to the ParB family.

1542390:KX01 RS06860
gene id: 1542390:KX01_RS06860
uniprot id: A0A1J0KSN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1542390:KX01 RS01475
gene id: 1542390:KX01_RS01475
uniprot id: A0A1J0KRC9
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS02945
gene id: 1542390:KX01_RS02945
uniprot id: A0A1J0KTX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1542390:KX01 RS02560
gene id: 1542390:KX01_RS02560
uniprot id: A0A1J0KRH5
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1542390:KX01 RS00265
gene id: 1542390:KX01_RS00265
uniprot id: A0A1J0KSB7
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS01300
gene id: 1542390:KX01_RS01300
uniprot id: A0A1J0KVB4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1542390:KX01 RS04645
gene id: 1542390:KX01_RS04645
uniprot id: A0A1J0KUE7
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1542390:KX01 RS04770
gene id: 1542390:KX01_RS04770
uniprot id: A0A1J0KRQ5
names: Similarity
messages: Belongs to the pyruvate kinase family.

1542390:KX01 RS07630
gene id: 1542390:KX01_RS07630
uniprot id: A0A1J0KUW5
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1542390:KX01 RS05070
gene id: 1542390:KX01_RS05070
uniprot id: A0A1J0KVW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

1542390:KX01 RS05815
gene id: 1542390:KX01_RS05815
uniprot id: A0A1J0KTM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1542390:KX01 RS07805
gene id: 1542390:KX01_RS07805
uniprot id: A0A1J0KVH0
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.

1542390:KX01 RS06255
gene id: 1542390:KX01_RS06255
uniprot id: A0A1J0KTJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1542390:KX01 RS05670
gene id: 1542390:KX01_RS05670
uniprot id: A0A1J0KSQ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1542390:KX01 RS05885
gene id: 1542390:KX01_RS05885
uniprot id: A0A1J0KRT6
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

1542390:KX01 RS00670
gene id: 1542390:KX01_RS00670
uniprot id: A0A1J0KVF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1542390:KX01 RS05135
gene id: 1542390:KX01_RS05135
uniprot id: A0A1J0KS43
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1542390:KX01 RS03970
gene id: 1542390:KX01_RS03970
uniprot id: A0A1J0KSM5
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS08710
gene id: 1542390:KX01_RS08710
uniprot id: A0A1J0KSZ1
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1542390:KX01 RS05340
gene id: 1542390:KX01_RS05340
uniprot id: A0A1J0KVN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1542390:KX01 RS03490
gene id: 1542390:KX01_RS03490
uniprot id: A0A1J0KW30
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS03370
gene id: 1542390:KX01_RS03370
uniprot id: A0A1J0KVY0
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

1542390:KX01 RS01070
gene id: 1542390:KX01_RS01070
uniprot id: A0A1J0KR91
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS00470
gene id: 1542390:KX01_RS00470
uniprot id: A0A1J0KRK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1542390:KX01 RS01910
gene id: 1542390:KX01_RS01910
uniprot id: A0A1J0KVA7
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1542390:KX01 RS08705
gene id: 1542390:KX01_RS08705
uniprot id: A0A1J0KSH7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1542390:KX01 RS05480
gene id: 1542390:KX01_RS05480
uniprot id: A0A1J0KU74
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1542390:KX01 RS06340
gene id: 1542390:KX01_RS06340
uniprot id: A0A1J0KW92
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1542390:KX01 RS07305
gene id: 1542390:KX01_RS07305
uniprot id: A0A1J0KVS0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1542390:KX01 RS03270
gene id: 1542390:KX01_RS03270
uniprot id: A0A1J0KT04
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1542390:KX01 RS00860
gene id: 1542390:KX01_RS00860
uniprot id: A0A1J0KUH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1542390:KX01 RS07485
gene id: 1542390:KX01_RS07485
uniprot id: A0A1J0KTU7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1542390:KX01 RS05470
gene id: 1542390:KX01_RS05470
uniprot id: A0A1J0KVI8
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1542390:KX01 RS07845
gene id: 1542390:KX01_RS07845
uniprot id: A0A1J0KVJ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

1542390:KX01 RS08660
gene id: 1542390:KX01_RS08660
uniprot id: A0A1J0KTR2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1542390:KX01 RS08610
gene id: 1542390:KX01_RS08610
uniprot id: A0A1J0KUQ9
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS02720
gene id: 1542390:KX01_RS02720
uniprot id: A0A1J0KRJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1542390:KX01 RS06625
gene id: 1542390:KX01_RS06625
uniprot id: A0A1J0KV79
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1542390:KX01 RS02415
gene id: 1542390:KX01_RS02415
uniprot id: A0A1J0KS47
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1542390:KX01 RS05765
gene id: 1542390:KX01_RS05765
uniprot id: A0A1J0KU41
names: Similarity
messages: Belongs to the UPF0145 family.

1542390:KX01 RS03700
gene id: 1542390:KX01_RS03700
uniprot id: A0A1J0KSE2
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1542390:KX01 RS07210
gene id: 1542390:KX01_RS07210
uniprot id: A0A1J0KVU9
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS02825
gene id: 1542390:KX01_RS02825
uniprot id: A0A1J0KS20
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1542390:KX01 RS07405
gene id: 1542390:KX01_RS07405
uniprot id: A0A1J0KSR0
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1542390:KX01 RS07835
gene id: 1542390:KX01_RS07835
uniprot id: A0A1J0KUK1
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1542390:KX01 RS00430
gene id: 1542390:KX01_RS00430
uniprot id: A0A1J0KTE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1542390:KX01 RS02525
gene id: 1542390:KX01_RS02525
uniprot id: A0A1J0KVC4
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS03720
gene id: 1542390:KX01_RS03720
uniprot id: A0A1J0KSH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1542390:KX01 RS01440
gene id: 1542390:KX01_RS01440
uniprot id: A0A1J0KTX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

1542390:KX01 RS02875
gene id: 1542390:KX01_RS02875
uniprot id: A0A1J0KVQ5
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1542390:KX01 RS05980
gene id: 1542390:KX01_RS05980
uniprot id: A0A1J0KVZ8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1542390:KX01 RS05680
gene id: 1542390:KX01_RS05680
uniprot id: A0A1J0KU65
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1542390:KX01 RS01790
gene id: 1542390:KX01_RS01790
uniprot id: A0A1J0KUH3
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1542390:KX01 RS00640
gene id: 1542390:KX01_RS00640
uniprot id: A0A1J0KRY0
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1542390:KX01 RS03855
gene id: 1542390:KX01_RS03855
uniprot id: A0A1J0KTH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1542390:KX01 RS00770
gene id: 1542390:KX01_RS00770
uniprot id: A0A1J0KU46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1542390:KX01 RS01680
gene id: 1542390:KX01_RS01680
uniprot id: A0A1J0KVY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Protein-1 exporter (TC 3.A.1.109) family.
messages: Membrane

1542390:KX01 RS04080
gene id: 1542390:KX01_RS04080
uniprot id: A0A1J0KR77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1542390:KX01 RS04090
gene id: 1542390:KX01_RS04090
uniprot id: A0A1J0KTD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1542390:KX01 RS03085
gene id: 1542390:KX01_RS03085
uniprot id: A0A1J0KS69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1542390:KX01 RS06060
gene id: 1542390:KX01_RS06060
uniprot id: A0A1J0KVH5
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1542390:KX01 RS06970
gene id: 1542390:KX01_RS06970
uniprot id: A0A1J0KRJ9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1542390:KX01 RS03345
gene id: 1542390:KX01_RS03345
uniprot id: A0A1J0KSS8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1542390:KX01 RS08555
gene id: 1542390:KX01_RS08555
uniprot id: A0A1J0KSA5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1542390:KX01 RS05460
gene id: 1542390:KX01_RS05460
uniprot id: A0A1J0KSP5
names: Similarity
messages: Belongs to the LOG family.

1542390:KX01 RS01955
gene id: 1542390:KX01_RS01955
uniprot id: A0A1J0KW56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1542390:KX01 RS04275
gene id: 1542390:KX01_RS04275
uniprot id: A0A1J0KSK6
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS04820
gene id: 1542390:KX01_RS04820
uniprot id: A0A1J0KVD0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1542390:KX01 RS07000
gene id: 1542390:KX01_RS07000
uniprot id: A0A1J0KSZ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1542390:KX01 RS04950
gene id: 1542390:KX01_RS04950
uniprot id: A0A1J0KV09
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

1542390:KX01 RS02800
gene id: 1542390:KX01_RS02800
uniprot id: A0A1J0KUK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1542390:KX01 RS08365
gene id: 1542390:KX01_RS08365
uniprot id: A0A1J0KTN2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1542390:KX01 RS07490
gene id: 1542390:KX01_RS07490
uniprot id: A0A1J0KV43
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1542390:KX01 RS04350
gene id: 1542390:KX01_RS04350
uniprot id: A0A1J0KUC9
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS07925
gene id: 1542390:KX01_RS07925
uniprot id: A0A1J0KUZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1542390:KX01 RS00235
gene id: 1542390:KX01_RS00235
uniprot id: A0A1J0KWF5
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS01935
gene id: 1542390:KX01_RS01935
uniprot id: A0A1J0KVD5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1542390:KX01 RS09010
gene id: 1542390:KX01_RS09010
uniprot id: A0A1J0KU07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1542390:KX01 RS04755
gene id: 1542390:KX01_RS04755
uniprot id: A0A1J0KUT5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1542390:KX01 RS06630
gene id: 1542390:KX01_RS06630
uniprot id: A0A1J0KV01
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1542390:KX01 RS01005
gene id: 1542390:KX01_RS01005
uniprot id: A0A1J0KW66
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1542390:KX01 RS08020
gene id: 1542390:KX01_RS08020
uniprot id: A0A1J0KUG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1542390:KX01 RS04795
gene id: 1542390:KX01_RS04795
uniprot id: A0A1J0KUS2
names: Similarity
messages: Belongs to the thioredoxin family.

1542390:KX01 RS05240
gene id: 1542390:KX01_RS05240
uniprot id: A0A1J0KU35
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1542390:KX01 RS02760
gene id: 1542390:KX01_RS02760
uniprot id: A0A1J0KSP3
names: Similarity
messages: Belongs to the threonine synthase family.

1542390:KX01 RS02690
gene id: 1542390:KX01_RS02690
uniprot id: A0A1J0KR53
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1542390:KX01 RS00865
gene id: 1542390:KX01_RS00865
uniprot id: A0A1J0KRI7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1542390:KX01 RS05625
gene id: 1542390:KX01_RS05625
uniprot id: A0A1J0KWI1
names: Caution
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1542390:KX01 RS03865
gene id: 1542390:KX01_RS03865
uniprot id: A0A1J0KTS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1542390:KX01 RS05940
gene id: 1542390:KX01_RS05940
uniprot id: A0A1J0KV94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

1542390:KX01 RS06230
gene id: 1542390:KX01_RS06230
uniprot id: A0A1J0KS62
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1542390:KX01 RS06875
gene id: 1542390:KX01_RS06875
uniprot id: A0A1J0KUE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1542390:KX01 RS01160
gene id: 1542390:KX01_RS01160
uniprot id: A0A1J0KVT1
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1542390:KX01 RS07700
gene id: 1542390:KX01_RS07700
uniprot id: A0A1J0KSY1
names: Similarity
messages: Belongs to the catalase family.

1542390:KX01 RS00765
gene id: 1542390:KX01_RS00765
uniprot id: A0A1J0KTS1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1542390:KX01 RS01545
gene id: 1542390:KX01_RS01545
uniprot id: A0A1J0KSK9
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS03315
gene id: 1542390:KX01_RS03315
uniprot id: A0A1J0KVB3
names: Subcellular Location Annotation
messages: Membrane

1542390:KX01 RS06250
gene id: 1542390:KX01_RS06250
uniprot id: A0A1J0KT50
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1542390:KX01 RS03295
gene id: 1542390:KX01_RS03295
uniprot id: A0A1J0KRS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1542390:KX01 RS01220
gene id: 1542390:KX01_RS01220
uniprot id: A0A1J0KV48
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.