153493:H3L98 RS09780
gene id: 153493:H3L98_RS09780
uniprot id: A0A7D7MXE1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

153493:H3L98 RS10010
gene id: 153493:H3L98_RS10010
uniprot id: A0A3P2A2N0
names: Subcellular Location Annotation
messages: Membrane

153493:H3L98 RS08905
gene id: 153493:H3L98_RS08905
uniprot id: A0A7D7MVU5
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

153493:H3L98 RS07715
gene id: 153493:H3L98_RS07715
uniprot id: A0A7D7S6N0
names: Subcellular Location Annotation
messages: Membrane

153493:H3L98 RS10130
gene id: 153493:H3L98_RS10130
uniprot id: A0A3P2A2K9
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

153493:H3L98 RS10640
gene id: 153493:H3L98_RS10640
uniprot id: A0A3P2A443
names: Similarity
messages: Belongs to the GbsR family.

153493:H3L98 RS06550
gene id: 153493:H3L98_RS06550
uniprot id: A0A7D7MV58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

153493:H3L98 RS08215
gene id: 153493:H3L98_RS08215
uniprot id: A0A7D7MX09
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

153493:H3L98 RS06800
gene id: 153493:H3L98_RS06800
uniprot id: A0A7D7RZ61
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

153493:H3L98 RS05215
gene id: 153493:H3L98_RS05215
uniprot id: A0A3P2A6L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

153493:H3L98 RS01470
gene id: 153493:H3L98_RS01470
uniprot id: A0A3P2A370
names: Subcellular Location Annotation
messages: Cell inner membrane

153493:H3L98 RS01235
gene id: 153493:H3L98_RS01235
uniprot id: A0A7D7N2M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

153493:H3L98 RS07225
gene id: 153493:H3L98_RS07225
uniprot id: A0A7D7MV95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

153493:H3L98 RS07695
gene id: 153493:H3L98_RS07695
uniprot id: A0A7D7RWT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

153493:H3L98 RS00715
gene id: 153493:H3L98_RS00715
uniprot id: A0A7D7MXW4
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

153493:H3L98 RS01395
gene id: 153493:H3L98_RS01395
uniprot id: A0A7D7MUB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

153493:H3L98 RS10065
gene id: 153493:H3L98_RS10065
uniprot id: A0A7D7RXF6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

153493:H3L98 RS01755
gene id: 153493:H3L98_RS01755
uniprot id: A0A3P2A5F8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

153493:H3L98 RS06480
gene id: 153493:H3L98_RS06480
uniprot id: A0A7D7S3U9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

153493:H3L98 RS07235
gene id: 153493:H3L98_RS07235
uniprot id: A0A7D7MT64
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

153493:H3L98 RS06765
gene id: 153493:H3L98_RS06765
uniprot id: A0A3P2A8A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

153493:H3L98 RS07085
gene id: 153493:H3L98_RS07085
uniprot id: A0A3P2ABP6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

153493:H3L98 RS07175
gene id: 153493:H3L98_RS07175
uniprot id: A0A3P2A8A5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

153493:H3L98 RS09110
gene id: 153493:H3L98_RS09110
uniprot id: A0A7D7MZ80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

153493:H3L98 RS01915
gene id: 153493:H3L98_RS01915
uniprot id: A0A7D7MYX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

153493:H3L98 RS07690
gene id: 153493:H3L98_RS07690
uniprot id: A0A7D7S6S4
names: Similarity
messages: Belongs to the PrpF family.

153493:H3L98 RS00540
gene id: 153493:H3L98_RS00540
uniprot id: A0A7D7T099
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

153493:H3L98 RS00675
gene id: 153493:H3L98_RS00675
uniprot id: A0A7D7MYM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

153493:H3L98 RS01750
gene id: 153493:H3L98_RS01750
uniprot id: A0A7D7RLI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

153493:H3L98 RS09820
gene id: 153493:H3L98_RS09820
uniprot id: A0A7D7S7B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

153493:H3L98 RS01790
gene id: 153493:H3L98_RS01790
uniprot id: A0A7D7S7V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

153493:H3L98 RS09085
gene id: 153493:H3L98_RS09085
uniprot id: A0A7D7N3B6
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

153493:H3L98 RS00710
gene id: 153493:H3L98_RS00710
uniprot id: A0A3P2A327
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

153493:H3L98 RS08945
gene id: 153493:H3L98_RS08945
uniprot id: A0A7D7RZT6
names: Subcellular Location Annotation
messages: Membrane

153493:H3L98 RS06940
gene id: 153493:H3L98_RS06940
uniprot id: A0A3P2ABS6
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

153493:H3L98 RS04600
gene id: 153493:H3L98_RS04600
uniprot id: A0A7D7SGN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

153493:H3L98 RS01835
gene id: 153493:H3L98_RS01835
uniprot id: A0A7D7MY02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

153493:H3L98 RS02075
gene id: 153493:H3L98_RS02075
uniprot id: A0A7D7MWP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

153493:H3L98 RS00440
gene id: 153493:H3L98_RS00440
uniprot id: A0A7D7N1W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

153493:H3L98 RS10725
gene id: 153493:H3L98_RS10725
uniprot id: A0A7D7MU14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

153493:H3L98 RS08890
gene id: 153493:H3L98_RS08890
uniprot id: A0A7D7MUH7
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

153493:H3L98 RS07380
gene id: 153493:H3L98_RS07380
uniprot id: A0A7D7SEW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

153493:H3L98 RS02900
gene id: 153493:H3L98_RS02900
uniprot id: A0A3P2A2A9
names: Similarity
messages: Belongs to the YjdM family.

153493:H3L98 RS09170
gene id: 153493:H3L98_RS09170
uniprot id: A0A7D7RZV4
names: Function
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.

153493:H3L98 RS03910
gene id: 153493:H3L98_RS03910
uniprot id: A0A7D7N4W4
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

153493:H3L98 RS00550
gene id: 153493:H3L98_RS00550
uniprot id: A0A7D7N1X6
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

153493:H3L98 RS03500
gene id: 153493:H3L98_RS03500
uniprot id: A0A7D7MVN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

153493:H3L98 RS00995
gene id: 153493:H3L98_RS00995
uniprot id: A0A7D7T0B9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

153493:H3L98 RS05860
gene id: 153493:H3L98_RS05860
uniprot id: A0A7D7MYE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

153493:H3L98 RS03520
gene id: 153493:H3L98_RS03520
uniprot id: A0A7D7RLX1
names: Subcellular Location Annotation
messages: Membrane

153493:H3L98 RS08860
gene id: 153493:H3L98_RS08860
uniprot id: A0A7D7N392
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

153493:H3L98 RS01825
gene id: 153493:H3L98_RS01825
uniprot id: A0A7D7N0A6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

153493:H3L98 RS09305
gene id: 153493:H3L98_RS09305
uniprot id: A0A7D7N259
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

153493:H3L98 RS00845
gene id: 153493:H3L98_RS00845
uniprot id: A0A7D7RW32
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

153493:H3L98 RS04055
gene id: 153493:H3L98_RS04055
uniprot id: A0A7D7N2J4
names: Subcellular Location Annotation
messages: Membrane

153493:H3L98 RS06700
gene id: 153493:H3L98_RS06700
uniprot id: A0A3P2A8J5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

153493:H3L98 RS07330
gene id: 153493:H3L98_RS07330
uniprot id: A0A7D7MWV0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS00140
gene id: 153493:H3L98_RS00140
uniprot id: A0A7D7RYX8
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

153493:H3L98 RS07560
gene id: 153493:H3L98_RS07560
uniprot id: A0A7D7MVC1
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

153493:H3L98 RS03795
gene id: 153493:H3L98_RS03795
uniprot id: A0A7D7N4V5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Cell surface
messages: Membrane

153493:H3L98 RS03800
gene id: 153493:H3L98_RS03800
uniprot id: A0A3P2A3F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

153493:H3L98 RS02310
gene id: 153493:H3L98_RS02310
uniprot id: A0A7D7RWG0
names: Similarity
messages: Belongs to the NAD synthetase family.

153493:H3L98 RS07150
gene id: 153493:H3L98_RS07150
uniprot id: A0A7D7RZA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

153493:H3L98 RS02190
gene id: 153493:H3L98_RS02190
uniprot id: A0A7D7MUJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Slam family.
messages: Cell outer membrane
messages: Membrane

153493:H3L98 RS07635
gene id: 153493:H3L98_RS07635
uniprot id: A0A7D7N1Q6
names: Similarity
messages: Belongs to the UPF0237 family.

153493:H3L98 RS09945
gene id: 153493:H3L98_RS09945
uniprot id: A0A7D7RXE5
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

153493:H3L98 RS02085
gene id: 153493:H3L98_RS02085
uniprot id: A0A3P2A8G8
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

153493:H3L98 RS01320
gene id: 153493:H3L98_RS01320
uniprot id: A0A7D7S0C6
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

153493:H3L98 RS03125
gene id: 153493:H3L98_RS03125
uniprot id: A0A7D7REG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

153493:H3L98 RS01695
gene id: 153493:H3L98_RS01695
uniprot id: A0A7D7T0F9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

153493:H3L98 RS00615
gene id: 153493:H3L98_RS00615
uniprot id: A0A7D7MU38
names: Similarity
messages: Belongs to the IMPACT family.

153493:H3L98 RS00740
gene id: 153493:H3L98_RS00740
uniprot id: A0A7D7RXR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

153493:H3L98 RS08430
gene id: 153493:H3L98_RS08430
uniprot id: A0A7D7MZ25
names: Similarity
messages: Belongs to the phosphohexose mutase family.

153493:H3L98 RS05235
gene id: 153493:H3L98_RS05235
uniprot id: A0A7D7T0Z3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

153493:H3L98 RS01415
gene id: 153493:H3L98_RS01415
uniprot id: A0A3P2A580
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

153493:H3L98 RS10090
gene id: 153493:H3L98_RS10090
uniprot id: A0A7D7S7C7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

153493:H3L98 RS05205
gene id: 153493:H3L98_RS05205
uniprot id: A0A7D7S8T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

153493:H3L98 RS06385
gene id: 153493:H3L98_RS06385
uniprot id: A0A7D7N2L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BexD/CtrA/VexA family.
messages: Cell outer membrane
messages: Membrane

153493:H3L98 RS08605
gene id: 153493:H3L98_RS08605
uniprot id: A0A7D7RX18
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

153493:H3L98 RS03960
gene id: 153493:H3L98_RS03960
uniprot id: A0A7D7RM16
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

153493:H3L98 RS08930
gene id: 153493:H3L98_RS08930
uniprot id: A0A7D7RX45
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

153493:H3L98 RS10600
gene id: 153493:H3L98_RS10600
uniprot id: A0A7D7MZ81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

153493:H3L98 RS00385
gene id: 153493:H3L98_RS00385
uniprot id: A0A7D7RVY9
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

153493:H3L98 RS02325
gene id: 153493:H3L98_RS02325
uniprot id: A0A7D7S5T3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS10735
gene id: 153493:H3L98_RS10735
uniprot id: A0A7D7S7K2
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

153493:H3L98 RS09710
gene id: 153493:H3L98_RS09710
uniprot id: A0A3P2A5U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

153493:H3L98 RS04365
gene id: 153493:H3L98_RS04365
uniprot id: A0A7D7MV16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

153493:H3L98 RS08185
gene id: 153493:H3L98_RS08185
uniprot id: A0A7D7N195
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

153493:H3L98 RS03090
gene id: 153493:H3L98_RS03090
uniprot id: A0A7D7N2H8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS06145
gene id: 153493:H3L98_RS06145
uniprot id: A0A7D7SZI6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

153493:H3L98 RS00345
gene id: 153493:H3L98_RS00345
uniprot id: A0A3P2A5H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

153493:H3L98 RS07210
gene id: 153493:H3L98_RS07210
uniprot id: A0A7D7MWU3
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

153493:H3L98 RS05590
gene id: 153493:H3L98_RS05590
uniprot id: A0A7D7S8X7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

153493:H3L98 RS01250
gene id: 153493:H3L98_RS01250
uniprot id: A0A7D7N002
names: Subcellular Location Annotation
messages: Membrane

153493:H3L98 RS00130
gene id: 153493:H3L98_RS00130
uniprot id: A0A7D7S3J8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

153493:H3L98 RS08420
gene id: 153493:H3L98_RS08420
uniprot id: A0A7D7MXX0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS09830
gene id: 153493:H3L98_RS09830
uniprot id: A0A3P2A5S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

153493:H3L98 RS04770
gene id: 153493:H3L98_RS04770
uniprot id: A0A7D7N536
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

153493:H3L98 RS01065
gene id: 153493:H3L98_RS01065
uniprot id: A0A7D7RW59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

153493:H3L98 RS01315
gene id: 153493:H3L98_RS01315
uniprot id: A0A7D7SFV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

153493:H3L98 RS04920
gene id: 153493:H3L98_RS04920
uniprot id: A0A7D7N316
names: Similarity
messages: Belongs to the peptidase U62 family.

153493:H3L98 RS08655
gene id: 153493:H3L98_RS08655
uniprot id: A0A7D7MXZ5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

153493:H3L98 RS10030
gene id: 153493:H3L98_RS10030
uniprot id: A0A7D7RDM1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS05020
gene id: 153493:H3L98_RS05020
uniprot id: A0A7D7N2T7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

153493:H3L98 RS08065
gene id: 153493:H3L98_RS08065
uniprot id: A0A7D7N331
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

153493:H3L98 RS01970
gene id: 153493:H3L98_RS01970
uniprot id: A0A7D7RY08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

153493:H3L98 RS09140
gene id: 153493:H3L98_RS09140
uniprot id: A0A7D7MTP6
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

153493:H3L98 RS01405
gene id: 153493:H3L98_RS01405
uniprot id: A0A3P2A364
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

153493:H3L98 RS08365
gene id: 153493:H3L98_RS08365
uniprot id: A0A7D7RV66
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS07455
gene id: 153493:H3L98_RS07455
uniprot id: A0A7D7RCX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

153493:H3L98 RS04670
gene id: 153493:H3L98_RS04670
uniprot id: A0A7D7N2R0
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

153493:H3L98 RS02960
gene id: 153493:H3L98_RS02960
uniprot id: A0A7D7RYY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

153493:H3L98 RS00905
gene id: 153493:H3L98_RS00905
uniprot id: A0A7D7N1U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

153493:H3L98 RS06055
gene id: 153493:H3L98_RS06055
uniprot id: A0A3P2A887
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters.

153493:H3L98 RS09590
gene id: 153493:H3L98_RS09590
uniprot id: A0A7D7RXA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

153493:H3L98 RS02525
gene id: 153493:H3L98_RS02525
uniprot id: A0A7D7MY52
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS04570
gene id: 153493:H3L98_RS04570
uniprot id: A0A7D7MV33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

153493:H3L98 RS04550
gene id: 153493:H3L98_RS04550
uniprot id: A0A7D7S185
names: Similarity
messages: Belongs to the peptidase M24B family.

153493:H3L98 RS06490
gene id: 153493:H3L98_RS06490
uniprot id: A0A7D7RZ37
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

153493:H3L98 RS00405
gene id: 153493:H3L98_RS00405
uniprot id: A0A7D7S585
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

153493:H3L98 RS07720
gene id: 153493:H3L98_RS07720
uniprot id: A0A7D7SZS3
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

153493:H3L98 RS07445
gene id: 153493:H3L98_RS07445
uniprot id: A0A7D7MU39
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

153493:H3L98 RS05420
gene id: 153493:H3L98_RS05420
uniprot id: A0A7D7S8V3
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

153493:H3L98 RS09425
gene id: 153493:H3L98_RS09425
uniprot id: A0A7D7N1F0
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

153493:H3L98 RS01900
gene id: 153493:H3L98_RS01900
uniprot id: A0A3P2A581
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

153493:H3L98 RS08940
gene id: 153493:H3L98_RS08940
uniprot id: A0A7D7SFA3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

153493:H3L98 RS03880
gene id: 153493:H3L98_RS03880
uniprot id: A0A7D7SGH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

153493:H3L98 RS03820
gene id: 153493:H3L98_RS03820
uniprot id: A0A7D7N0S1
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

153493:H3L98 RS08715
gene id: 153493:H3L98_RS08715
uniprot id: A0A7D7RX28
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

153493:H3L98 RS06430
gene id: 153493:H3L98_RS06430
uniprot id: A0A7D7MVF8
names: Subcellular Location Annotation
messages: Membrane

153493:H3L98 RS06420
gene id: 153493:H3L98_RS06420
uniprot id: A0A7D7MWN8
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

153493:H3L98 RS08830
gene id: 153493:H3L98_RS08830
uniprot id: A0A3P2A7X8
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

153493:H3L98 RS08305
gene id: 153493:H3L98_RS08305
uniprot id: A0A7D7MXV8
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.

153493:H3L98 RS02970
gene id: 153493:H3L98_RS02970
uniprot id: A0A7D7N2H1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

153493:H3L98 RS03515
gene id: 153493:H3L98_RS03515
uniprot id: A0A7D7MX36
names: Subcellular Location Annotation
messages: Membrane

153493:H3L98 RS08955
gene id: 153493:H3L98_RS08955
uniprot id: A0A7D7SZZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

153493:H3L98 RS07775
gene id: 153493:H3L98_RS07775
uniprot id: A0A7D7MVH9
names: Similarity
messages: Belongs to the BolA/IbaG family.

153493:H3L98 RS07855
gene id: 153493:H3L98_RS07855
uniprot id: A0A7D7N1S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

153493:H3L98 RS07165
gene id: 153493:H3L98_RS07165
uniprot id: A0A7D7S6I9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

153493:H3L98 RS08235
gene id: 153493:H3L98_RS08235
uniprot id: A0A7D7MTG7
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

153493:H3L98 RS00695
gene id: 153493:H3L98_RS00695
uniprot id: A0A7D7MXR1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

153493:H3L98 RS10770
gene id: 153493:H3L98_RS10770
uniprot id: A0A7D7N3X8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

153493:H3L98 RS05545
gene id: 153493:H3L98_RS05545
uniprot id: A0A7D7RYT7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

153493:H3L98 RS04980
gene id: 153493:H3L98_RS04980
uniprot id: A0A7D7S101
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

153493:H3L98 RS04060
gene id: 153493:H3L98_RS04060
uniprot id: A0A7D7N0U1
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

153493:H3L98 RS04515
gene id: 153493:H3L98_RS04515
uniprot id: A0A7D7N2T9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS01680
gene id: 153493:H3L98_RS01680
uniprot id: A0A7D7S0E9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

153493:H3L98 RS01005
gene id: 153493:H3L98_RS01005
uniprot id: A0A3P2A0S7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

153493:H3L98 RS05975
gene id: 153493:H3L98_RS05975
uniprot id: A0A7D7MTI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS04250
gene id: 153493:H3L98_RS04250
uniprot id: A0A7D7S8N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

153493:H3L98 RS03860
gene id: 153493:H3L98_RS03860
uniprot id: A0A3P2A3C4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

153493:H3L98 RS09350
gene id: 153493:H3L98_RS09350
uniprot id: A0A7D7RKY2
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

153493:H3L98 RS02740
gene id: 153493:H3L98_RS02740
uniprot id: A0A7D7MXX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

153493:H3L98 RS08870
gene id: 153493:H3L98_RS08870
uniprot id: A0A7D7N216
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

153493:H3L98 RS09975
gene id: 153493:H3L98_RS09975
uniprot id: A0A7D7S7B9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

153493:H3L98 RS03640
gene id: 153493:H3L98_RS03640
uniprot id: A0A7D7S8F1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

153493:H3L98 RS02845
gene id: 153493:H3L98_RS02845
uniprot id: A0A7D7MVC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

153493:H3L98 RS05320
gene id: 153493:H3L98_RS05320
uniprot id: A0A7D7S6S7
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

153493:H3L98 RS03280
gene id: 153493:H3L98_RS03280
uniprot id: A0A3P2A1L7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

153493:H3L98 RS05220
gene id: 153493:H3L98_RS05220
uniprot id: A0A7D7SGT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

153493:H3L98 RS09220
gene id: 153493:H3L98_RS09220
uniprot id: A0A7D7MUK6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

153493:H3L98 RS06210
gene id: 153493:H3L98_RS06210
uniprot id: A0A7D7RUE8
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

153493:H3L98 RS01720
gene id: 153493:H3L98_RS01720
uniprot id: A0A7D7N212
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

153493:H3L98 RS04890
gene id: 153493:H3L98_RS04890
uniprot id: A0A7D7N3B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

153493:H3L98 RS09450
gene id: 153493:H3L98_RS09450
uniprot id: A0A7D7MVY2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

153493:H3L98 RS00470
gene id: 153493:H3L98_RS00470
uniprot id: A0A7D7MV04
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

153493:H3L98 RS07270
gene id: 153493:H3L98_RS07270
uniprot id: A0A7D7S6J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

153493:H3L98 RS07620
gene id: 153493:H3L98_RS07620
uniprot id: A0A7D7SZR5
names: Similarity
messages: Belongs to the DprA/Smf family.

153493:H3L98 RS01990
gene id: 153493:H3L98_RS01990
uniprot id: A0A7D7S7W5
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

153493:H3L98 RS03845
gene id: 153493:H3L98_RS03845
uniprot id: A0A7D7MXA1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

153493:H3L98 RS09195
gene id: 153493:H3L98_RS09195
uniprot id: A0A7D7N1H5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Cell surface
messages: Membrane

153493:H3L98 RS01895
gene id: 153493:H3L98_RS01895
uniprot id: A0A7D7T0H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

153493:H3L98 RS00430
gene id: 153493:H3L98_RS00430
uniprot id: A0A7D7N194
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein.
messages: Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.

153493:H3L98 RS09970
gene id: 153493:H3L98_RS09970
uniprot id: A0A7D7S011
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

153493:H3L98 RS06730
gene id: 153493:H3L98_RS06730
uniprot id: A0A7D7MXH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

153493:H3L98 RS01775
gene id: 153493:H3L98_RS01775
uniprot id: A0A7D7S5L6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

153493:H3L98 RS05565
gene id: 153493:H3L98_RS05565
uniprot id: A0A7D7S144
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

153493:H3L98 RS05885
gene id: 153493:H3L98_RS05885
uniprot id: A0A7D7RK55
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

153493:H3L98 RS07540
gene id: 153493:H3L98_RS07540
uniprot id: A0A7D7MYV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

153493:H3L98 RS07705
gene id: 153493:H3L98_RS07705
uniprot id: A0A7D7SF13
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

153493:H3L98 RS08920
gene id: 153493:H3L98_RS08920
uniprot id: A0A7D7RVC5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

153493:H3L98 RS01815
gene id: 153493:H3L98_RS01815
uniprot id: A0A7D7MYW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

153493:H3L98 RS01345
gene id: 153493:H3L98_RS01345
uniprot id: A0A7D7N2M7
names: Subcellular Location Annotation
messages: Membrane

153493:H3L98 RS08705
gene id: 153493:H3L98_RS08705
uniprot id: A0A7D7RVA1
names: Subcellular Location Annotation
messages: Membrane

153493:H3L98 RS05245
gene id: 153493:H3L98_RS05245
uniprot id: A0A7D7N2Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

153493:H3L98 RS02245
gene id: 153493:H3L98_RS02245
uniprot id: A0A7D7N4D8
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

153493:H3L98 RS09385
gene id: 153493:H3L98_RS09385
uniprot id: A0A7D7RZX0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS09520
gene id: 153493:H3L98_RS09520
uniprot id: A0A7D7N277
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

153493:H3L98 RS03130
gene id: 153493:H3L98_RS03130
uniprot id: A0A3P2A3R1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

153493:H3L98 RS06720
gene id: 153493:H3L98_RS06720
uniprot id: A0A7D7N0X0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.

153493:H3L98 RS02275
gene id: 153493:H3L98_RS02275
uniprot id: A0A3P2A6C3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

153493:H3L98 RS01905
gene id: 153493:H3L98_RS01905
uniprot id: A0A3P2A8K0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

153493:H3L98 RS07545
gene id: 153493:H3L98_RS07545
uniprot id: A0A3P2A8Q4
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

153493:H3L98 RS00600
gene id: 153493:H3L98_RS00600
uniprot id: A0A7D7RF13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

153493:H3L98 RS01355
gene id: 153493:H3L98_RS01355
uniprot id: A0A7D7MYS8
names: Similarity
messages: Belongs to the peptidase M10B family.

153493:H3L98 RS07500
gene id: 153493:H3L98_RS07500
uniprot id: A0A7D7RZD7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

153493:H3L98 RS01855
gene id: 153493:H3L98_RS01855
uniprot id: A0A7D7MUG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

153493:H3L98 RS05870
gene id: 153493:H3L98_RS05870
uniprot id: A0A7D7MWJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

153493:H3L98 RS07435
gene id: 153493:H3L98_RS07435
uniprot id: A0A7D7MYT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. Tam family.
messages: Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
messages: Cytoplasm

153493:H3L98 RS06615
gene id: 153493:H3L98_RS06615
uniprot id: A0A7D7N2N5
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

153493:H3L98 RS04815
gene id: 153493:H3L98_RS04815
uniprot id: A0A3P2A8X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

153493:H3L98 RS06735
gene id: 153493:H3L98_RS06735
uniprot id: A0A3P2A9L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

153493:H3L98 RS08390
gene id: 153493:H3L98_RS08390
uniprot id: A0A7D7RZP3
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

153493:H3L98 RS05955
gene id: 153493:H3L98_RS05955
uniprot id: A0A7D7N1C5
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

153493:H3L98 RS01220
gene id: 153493:H3L98_RS01220
uniprot id: A0A7D7T0D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

153493:H3L98 RS09440
gene id: 153493:H3L98_RS09440
uniprot id: A0A7D7MXB0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

153493:H3L98 RS06415
gene id: 153493:H3L98_RS06415
uniprot id: A0A7D7MTT8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

153493:H3L98 RS10075
gene id: 153493:H3L98_RS10075
uniprot id: A0A7D7SFI5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

153493:H3L98 RS03100
gene id: 153493:H3L98_RS03100
uniprot id: A0A7D7MZ65
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

153493:H3L98 RS05370
gene id: 153493:H3L98_RS05370
uniprot id: A0A7D7N2W6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.

153493:H3L98 RS01715
gene id: 153493:H3L98_RS01715
uniprot id: A0A7D7MYV3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

153493:H3L98 RS00145
gene id: 153493:H3L98_RS00145
uniprot id: A0A3P2A1F1
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

153493:H3L98 RS02615
gene id: 153493:H3L98_RS02615
uniprot id: A0A7D7N2E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

153493:H3L98 RS05175
gene id: 153493:H3L98_RS05175
uniprot id: A0A3P2A345
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

153493:H3L98 RS08455
gene id: 153493:H3L98_RS08455
uniprot id: A0A7D7RKN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

153493:H3L98 RS09250
gene id: 153493:H3L98_RS09250
uniprot id: A0A3P2A7J3
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.

153493:H3L98 RS09445
gene id: 153493:H3L98_RS09445
uniprot id: A0A7D7RDG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

153493:H3L98 RS09050
gene id: 153493:H3L98_RS09050
uniprot id: A0A7D7S736
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

153493:H3L98 RS05505
gene id: 153493:H3L98_RS05505
uniprot id: A0A3P2A926
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

153493:H3L98 RS07370
gene id: 153493:H3L98_RS07370
uniprot id: A0A7D7RWQ6
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

153493:H3L98 RS00890
gene id: 153493:H3L98_RS00890
uniprot id: A0A7D7N202
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

153493:H3L98 RS04750
gene id: 153493:H3L98_RS04750
uniprot id: A0A7D7S8I1
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

153493:H3L98 RS07250
gene id: 153493:H3L98_RS07250
uniprot id: A0A7D7RWP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell inner membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

153493:H3L98 RS06775
gene id: 153493:H3L98_RS06775
uniprot id: A0A3P2A8C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

153493:H3L98 RS08195
gene id: 153493:H3L98_RS08195
uniprot id: A0A7D7MXU8
names: Similarity
messages: Belongs to the citrate synthase family.

153493:H3L98 RS05825
gene id: 153493:H3L98_RS05825
uniprot id: A0A7D7SZG6
names: Subcellular Location Annotation
messages: Mitochondrion

153493:H3L98 RS04505
gene id: 153493:H3L98_RS04505
uniprot id: A0A7D7T0V7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

153493:H3L98 RS07520
gene id: 153493:H3L98_RS07520
uniprot id: A0A7D7N126
names: Subcellular Location Annotation
messages: Membrane

153493:H3L98 RS01760
gene id: 153493:H3L98_RS01760
uniprot id: A0A3P2AAI0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

153493:H3L98 RS10170
gene id: 153493:H3L98_RS10170
uniprot id: A0A7D7RXG7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

153493:H3L98 RS06835
gene id: 153493:H3L98_RS06835
uniprot id: A0A7D7MXI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.
messages: The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.

153493:H3L98 RS02645
gene id: 153493:H3L98_RS02645
uniprot id: A0A7D7MY62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Membrane

153493:H3L98 RS01265
gene id: 153493:H3L98_RS01265
uniprot id: A0A7D7RDY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

153493:H3L98 RS00880
gene id: 153493:H3L98_RS00880
uniprot id: A0A7D7T0B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

153493:H3L98 RS08415
gene id: 153493:H3L98_RS08415
uniprot id: A0A7D7N1X7
names: Similarity
messages: Belongs to the peptidase S11 family.

153493:H3L98 RS05995
gene id: 153493:H3L98_RS05995
uniprot id: A0A7D7RK64
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

153493:H3L98 RS04245
gene id: 153493:H3L98_RS04245
uniprot id: A0A3P2A2J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

153493:H3L98 RS04460
gene id: 153493:H3L98_RS04460
uniprot id: A0A7D7RM50
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

153493:H3L98 RS08510
gene id: 153493:H3L98_RS08510
uniprot id: A0A7D7S6X0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

153493:H3L98 RS05775
gene id: 153493:H3L98_RS05775
uniprot id: A0A3P2A748
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

153493:H3L98 RS09435
gene id: 153493:H3L98_RS09435
uniprot id: A0A7D7MUN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

153493:H3L98 RS07740
gene id: 153493:H3L98_RS07740
uniprot id: A0A7D7MXQ5
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

153493:H3L98 RS08120
gene id: 153493:H3L98_RS08120
uniprot id: A0A7D7MVM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

153493:H3L98 RS02250
gene id: 153493:H3L98_RS02250
uniprot id: A0A7D7N2Z8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

153493:H3L98 RS05745
gene id: 153493:H3L98_RS05745
uniprot id: A0A7D7N0L6
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

153493:H3L98 RS05255
gene id: 153493:H3L98_RS05255
uniprot id: A0A7D7MZM8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

153493:H3L98 RS02490
gene id: 153493:H3L98_RS02490
uniprot id: A0A7D7N4F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

153493:H3L98 RS07960
gene id: 153493:H3L98_RS07960
uniprot id: A0A7D7N322
names: Similarity
messages: Belongs to the YfgM family.

153493:H3L98 RS09775
gene id: 153493:H3L98_RS09775
uniprot id: A0A7D7MUQ6
names: Subcellular Location Annotation
messages: Membrane

153493:H3L98 RS01875
gene id: 153493:H3L98_RS01875
uniprot id: A0A3P2A8L8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

153493:H3L98 RS08840
gene id: 153493:H3L98_RS08840
uniprot id: A0A7D7SF97
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

153493:H3L98 RS09400
gene id: 153493:H3L98_RS09400
uniprot id: A0A3P2A8Y1
names: Similarity
messages: Belongs to the GSP E family.

153493:H3L98 RS03790
gene id: 153493:H3L98_RS03790
uniprot id: A0A7D7T0S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

153493:H3L98 RS00580
gene id: 153493:H3L98_RS00580
uniprot id: A0A7D7MV12
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

153493:H3L98 RS09345
gene id: 153493:H3L98_RS09345
uniprot id: A0A7D7MVX5
names: Similarity
messages: Belongs to the HesB/IscA family.

153493:H3L98 RS00530
gene id: 153493:H3L98_RS00530
uniprot id: A0A7D7MYZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

153493:H3L98 RS01080
gene id: 153493:H3L98_RS01080
uniprot id: A0A7D7RXT3
names: Subcellular Location Annotation
messages: Membrane

153493:H3L98 RS09225
gene id: 153493:H3L98_RS09225
uniprot id: A0A3P2ABA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

153493:H3L98 RS05645
gene id: 153493:H3L98_RS05645
uniprot id: A0A3P2A714
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

153493:H3L98 RS06220
gene id: 153493:H3L98_RS06220
uniprot id: A0A7D7RWF9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

153493:H3L98 RS06325
gene id: 153493:H3L98_RS06325
uniprot id: A0A7D7RK88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

153493:H3L98 RS06785
gene id: 153493:H3L98_RS06785
uniprot id: A0A7D7RWL1
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

153493:H3L98 RS09545
gene id: 153493:H3L98_RS09545
uniprot id: A0A7D7MZB9
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

153493:H3L98 RS04005
gene id: 153493:H3L98_RS04005
uniprot id: A0A7D7T0T3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

153493:H3L98 RS03510
gene id: 153493:H3L98_RS03510
uniprot id: A0A7D7REJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

153493:H3L98 RS02580
gene id: 153493:H3L98_RS02580
uniprot id: A0A7D7RY53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

153493:H3L98 RS02925
gene id: 153493:H3L98_RS02925
uniprot id: A0A7D7RY81
names: Subcellular Location Annotation
messages: Membrane

153493:H3L98 RS05265
gene id: 153493:H3L98_RS05265
uniprot id: A0A7D7N2V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

153493:H3L98 RS00650
gene id: 153493:H3L98_RS00650
uniprot id: A0A7D7S7K8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

153493:H3L98 RS01040
gene id: 153493:H3L98_RS01040
uniprot id: A0A7D7MXT3
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

153493:H3L98 RS08755
gene id: 153493:H3L98_RS08755
uniprot id: A0A7D7N1D7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

153493:H3L98 RS05595
gene id: 153493:H3L98_RS05595
uniprot id: A0A7D7N3H0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Cell surface
messages: Membrane
messages: Periplasm
messages: Secreted

153493:H3L98 RS02855
gene id: 153493:H3L98_RS02855
uniprot id: A0A7D7N2X3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

153493:H3L98 RS01120
gene id: 153493:H3L98_RS01120
uniprot id: A0A7D7RYV1
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

153493:H3L98 RS06130
gene id: 153493:H3L98_RS06130
uniprot id: A0A7D7SEM6
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

153493:H3L98 RS07400
gene id: 153493:H3L98_RS07400
uniprot id: A0A7D7SZQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

153493:H3L98 RS01465
gene id: 153493:H3L98_RS01465
uniprot id: A0A7D7N2N6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

153493:H3L98 RS07180
gene id: 153493:H3L98_RS07180
uniprot id: A0A3P2AD89
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

153493:H3L98 RS08495
gene id: 153493:H3L98_RS08495
uniprot id: A0A7D7S4G8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

153493:H3L98 RS10765
gene id: 153493:H3L98_RS10765
uniprot id: A0A7D7T087
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family. HpaC subfamily.

153493:H3L98 RS10000
gene id: 153493:H3L98_RS10000
uniprot id: A0A7D7MYC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

153493:H3L98 RS03945
gene id: 153493:H3L98_RS03945
uniprot id: A0A7D7MYF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

153493:H3L98 RS01710
gene id: 153493:H3L98_RS01710
uniprot id: A0A7D7N2P7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

153493:H3L98 RS06260
gene id: 153493:H3L98_RS06260
uniprot id: A0A7D7SZJ4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS10540
gene id: 153493:H3L98_RS10540
uniprot id: A0A7D7N3V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

153493:H3L98 RS07415
gene id: 153493:H3L98_RS07415
uniprot id: A0A7D7N1N8
names: Similarity
messages: Belongs to the citrate synthase family.

153493:H3L98 RS04880
gene id: 153493:H3L98_RS04880
uniprot id: A0A7D7N548
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

153493:H3L98 RS05270
gene id: 153493:H3L98_RS05270
uniprot id: A0A7D7N153
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

153493:H3L98 RS04875
gene id: 153493:H3L98_RS04875
uniprot id: A0A7D7T0X6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

153493:H3L98 RS07230
gene id: 153493:H3L98_RS07230
uniprot id: A0A7D7RKE6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

153493:H3L98 RS00760
gene id: 153493:H3L98_RS00760
uniprot id: A0A7D7S7M0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

153493:H3L98 RS02035
gene id: 153493:H3L98_RS02035
uniprot id: A0A7D7N2R6
names: Similarity
messages: Belongs to the opacity porin family.

153493:H3L98 RS09635
gene id: 153493:H3L98_RS09635
uniprot id: A0A7D7MY95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

153493:H3L98 RS02200
gene id: 153493:H3L98_RS02200
uniprot id: A0A7D7S849
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

153493:H3L98 RS07100
gene id: 153493:H3L98_RS07100
uniprot id: A0A7D7MV88
names: Similarity
messages: Belongs to the CmpA/NrtA family.

153493:H3L98 RS05670
gene id: 153493:H3L98_RS05670
uniprot id: A0A7D7S6W1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

153493:H3L98 RS09765
gene id: 153493:H3L98_RS09765
uniprot id: A0A7D7N1I3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

153493:H3L98 RS10775
gene id: 153493:H3L98_RS10775
uniprot id: A0A7D7RMP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

153493:H3L98 RS07280
gene id: 153493:H3L98_RS07280
uniprot id: A0A7D7N2W8
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

153493:H3L98 RS08530
gene id: 153493:H3L98_RS08530
uniprot id: A0A7D7N1Y2
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

153493:H3L98 RS02115
gene id: 153493:H3L98_RS02115
uniprot id: A0A7D7S0H1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

153493:H3L98 RS05725
gene id: 153493:H3L98_RS05725
uniprot id: A0A7D7N2E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

153493:H3L98 RS08465
gene id: 153493:H3L98_RS08465
uniprot id: A0A3P2A4N0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

153493:H3L98 RS07275
gene id: 153493:H3L98_RS07275
uniprot id: A0A7D7SZP7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS08205
gene id: 153493:H3L98_RS08205
uniprot id: A0A3P2A666
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

153493:H3L98 RS06375
gene id: 153493:H3L98_RS06375
uniprot id: A0A7D7S6C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

153493:H3L98 RS07645
gene id: 153493:H3L98_RS07645
uniprot id: A0A7D7N116
names: Subcellular Location Annotation
messages: Membrane

153493:H3L98 RS05695
gene id: 153493:H3L98_RS05695
uniprot id: A0A7D7N5G8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

153493:H3L98 RS06515
gene id: 153493:H3L98_RS06515
uniprot id: A0A7D7N1F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

153493:H3L98 RS01485
gene id: 153493:H3L98_RS01485
uniprot id: A0A7D7N022
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

153493:H3L98 RS09715
gene id: 153493:H3L98_RS09715
uniprot id: A0A3P2A716
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

153493:H3L98 RS05625
gene id: 153493:H3L98_RS05625
uniprot id: A0A7D7MYY3
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

153493:H3L98 RS01180
gene id: 153493:H3L98_RS01180
uniprot id: A0A7D7MU85
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

153493:H3L98 RS03690
gene id: 153493:H3L98_RS03690
uniprot id: A0A7D7N2M6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

153493:H3L98 RS10220
gene id: 153493:H3L98_RS10220
uniprot id: A0A7D7N1L7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

153493:H3L98 RS05935
gene id: 153493:H3L98_RS05935
uniprot id: A0A7D7S675
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS04300
gene id: 153493:H3L98_RS04300
uniprot id: A0A7D7N4Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

153493:H3L98 RS10035
gene id: 153493:H3L98_RS10035
uniprot id: A0A7D7MW28
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

153493:H3L98 RS10080
gene id: 153493:H3L98_RS10080
uniprot id: A0A7D7S014
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

153493:H3L98 RS06605
gene id: 153493:H3L98_RS06605
uniprot id: A0A7D7S6E5
names: Similarity
messages: Belongs to the P(II) protein family.

153493:H3L98 RS00655
gene id: 153493:H3L98_RS00655
uniprot id: A0A7D7T0A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

153493:H3L98 RS02290
gene id: 153493:H3L98_RS02290
uniprot id: A0A7D7REA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

153493:H3L98 RS02390
gene id: 153493:H3L98_RS02390
uniprot id: A0A7D7N0E1
names: Subcellular Location Annotation
messages: Membrane

153493:H3L98 RS10560
gene id: 153493:H3L98_RS10560
uniprot id: A0A7D7MYI0
names: Similarity
messages: Belongs to the ArsC family.

153493:H3L98 RS05170
gene id: 153493:H3L98_RS05170
uniprot id: A0A7D7MW46
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

153493:H3L98 RS01730
gene id: 153493:H3L98_RS01730
uniprot id: A0A3P2A5I9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

153493:H3L98 RS09145
gene id: 153493:H3L98_RS09145
uniprot id: A0A3P2A691
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS03015
gene id: 153493:H3L98_RS03015
uniprot id: A0A3P2A270
names: Similarity
messages: Belongs to the Fur family.

153493:H3L98 RS03525
gene id: 153493:H3L98_RS03525
uniprot id: A0A7D7N1G4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS07710
gene id: 153493:H3L98_RS07710
uniprot id: A0A7D7RZF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

153493:H3L98 RS05105
gene id: 153493:H3L98_RS05105
uniprot id: A0A7D7SGT0
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

153493:H3L98 RS08730
gene id: 153493:H3L98_RS08730
uniprot id: A0A7D7SF87
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

153493:H3L98 RS08275
gene id: 153493:H3L98_RS08275
uniprot id: A0A7D7S6S2
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

153493:H3L98 RS09105
gene id: 153493:H3L98_RS09105
uniprot id: A0A7D7N1C8
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

153493:H3L98 RS06180
gene id: 153493:H3L98_RS06180
uniprot id: A0A7D7MTQ3
names: Similarity
messages: Belongs to the threonine synthase family.

153493:H3L98 RS03885
gene id: 153493:H3L98_RS03885
uniprot id: A0A7D7S0T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

153493:H3L98 RS07730
gene id: 153493:H3L98_RS07730
uniprot id: A0A7D7N147
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

153493:H3L98 RS05950
gene id: 153493:H3L98_RS05950
uniprot id: A0A7D7N0P7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

153493:H3L98 RS03380
gene id: 153493:H3L98_RS03380
uniprot id: A0A7D7MZX2
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

153493:H3L98 RS01975
gene id: 153493:H3L98_RS01975
uniprot id: A0A7D7S5R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

153493:H3L98 RS08070
gene id: 153493:H3L98_RS08070
uniprot id: A0A7D7N181
names: Similarity
messages: Belongs to the SAICAR synthetase family.

153493:H3L98 RS01110
gene id: 153493:H3L98_RS01110
uniprot id: A0A7D7S7P8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

153493:H3L98 RS08480
gene id: 153493:H3L98_RS08480
uniprot id: A0A7D7RX04
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

153493:H3L98 RS06755
gene id: 153493:H3L98_RS06755
uniprot id: A0A3P2A8I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

153493:H3L98 RS03385
gene id: 153493:H3L98_RS03385
uniprot id: A0A7D7MYA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

153493:H3L98 RS05470
gene id: 153493:H3L98_RS05470
uniprot id: A0A7D7N3F7
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

153493:H3L98 RS07015
gene id: 153493:H3L98_RS07015
uniprot id: A0A7D7RWM6
names: Similarity
messages: Belongs to the PhoH family.

153493:H3L98 RS03865
gene id: 153493:H3L98_RS03865
uniprot id: A0A3P2A6U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

153493:H3L98 RS08645
gene id: 153493:H3L98_RS08645
uniprot id: A0A3P2A6F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

153493:H3L98 RS07930
gene id: 153493:H3L98_RS07930
uniprot id: A0A7D7SF27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

153493:H3L98 RS00575
gene id: 153493:H3L98_RS00575
uniprot id: A0A7D7MZP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

153493:H3L98 RS03990
gene id: 153493:H3L98_RS03990
uniprot id: A0A7D7SGJ4
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

153493:H3L98 RS00885
gene id: 153493:H3L98_RS00885
uniprot id: A0A7D7N423
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

153493:H3L98 RS03875
gene id: 153493:H3L98_RS03875
uniprot id: A0A7D7S692
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Membrane

153493:H3L98 RS08110
gene id: 153493:H3L98_RS08110
uniprot id: A0A7D7MWZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

153493:H3L98 RS05260
gene id: 153493:H3L98_RS05260
uniprot id: A0A7D7RMJ4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

153493:H3L98 RS10070
gene id: 153493:H3L98_RS10070
uniprot id: A0A7D7S4Z3
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

153493:H3L98 RS05075
gene id: 153493:H3L98_RS05075
uniprot id: A0A7D7RMA5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

153493:H3L98 RS05810
gene id: 153493:H3L98_RS05810
uniprot id: A0A7D7SEK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

153493:H3L98 RS03305
gene id: 153493:H3L98_RS03305
uniprot id: A0A7D7S8D0
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

153493:H3L98 RS01525
gene id: 153493:H3L98_RS01525
uniprot id: A0A7D7S7U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

153493:H3L98 RS02865
gene id: 153493:H3L98_RS02865
uniprot id: A0A7D7N2A5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

153493:H3L98 RS05930
gene id: 153493:H3L98_RS05930
uniprot id: A0A7D7RZ00
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

153493:H3L98 RS07490
gene id: 153493:H3L98_RS07490
uniprot id: A0A7D7S488
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

153493:H3L98 RS04590
gene id: 153493:H3L98_RS04590
uniprot id: A0A7D7RYL0
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

153493:H3L98 RS01845
gene id: 153493:H3L98_RS01845
uniprot id: A0A3P2A6V8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

153493:H3L98 RS10045
gene id: 153493:H3L98_RS10045
uniprot id: A0A7D7RL39
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

153493:H3L98 RS03610
gene id: 153493:H3L98_RS03610
uniprot id: A0A7D7MYC3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

153493:H3L98 RS05140
gene id: 153493:H3L98_RS05140
uniprot id: A0A7D7N568
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

153493:H3L98 RS03135
gene id: 153493:H3L98_RS03135
uniprot id: A0A3P2A2K4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

153493:H3L98 RS10645
gene id: 153493:H3L98_RS10645
uniprot id: A0A7D7S052
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

153493:H3L98 RS00720
gene id: 153493:H3L98_RS00720
uniprot id: A0A7D7MU43
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS07350
gene id: 153493:H3L98_RS07350
uniprot id: A0A7D7RKF2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

153493:H3L98 RS07625
gene id: 153493:H3L98_RS07625
uniprot id: A0A7D7N2Z6
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

153493:H3L98 RS08580
gene id: 153493:H3L98_RS08580
uniprot id: A0A7D7MVS1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

153493:H3L98 RS02320
gene id: 153493:H3L98_RS02320
uniprot id: A0A7D7RY32
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

153493:H3L98 RS05480
gene id: 153493:H3L98_RS05480
uniprot id: A0A7D7N2X5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.

153493:H3L98 RS08085
gene id: 153493:H3L98_RS08085
uniprot id: A0A7D7MXT6
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

153493:H3L98 RS05690
gene id: 153493:H3L98_RS05690
uniprot id: A0A7D7T114
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

153493:H3L98 RS02060
gene id: 153493:H3L98_RS02060
uniprot id: A0A7D7MY23
names: Similarity
messages: Belongs to the UDPGP type 2 family.

153493:H3L98 RS01385
gene id: 153493:H3L98_RS01385
uniprot id: A0A7D7MWH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

153493:H3L98 RS01055
gene id: 153493:H3L98_RS01055
uniprot id: A0A7D7RLD8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

153493:H3L98 RS06930
gene id: 153493:H3L98_RS06930
uniprot id: A0A7D7RZ77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

153493:H3L98 RS10150
gene id: 153493:H3L98_RS10150
uniprot id: A0A7D7RL50
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

153493:H3L98 RS04440
gene id: 153493:H3L98_RS04440
uniprot id: A0A7D7MVZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

153493:H3L98 RS04445
gene id: 153493:H3L98_RS04445
uniprot id: A0A7D7MYI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

153493:H3L98 RS04340
gene id: 153493:H3L98_RS04340
uniprot id: A0A7D7MVY3
names: Similarity
messages: Belongs to the GST superfamily.

153493:H3L98 RS00640
gene id: 153493:H3L98_RS00640
uniprot id: A0A3P2A547
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

153493:H3L98 RS05210
gene id: 153493:H3L98_RS05210
uniprot id: A0A7D7RYQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

153493:H3L98 RS08935
gene id: 153493:H3L98_RS08935
uniprot id: A0A7D7S4K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

153493:H3L98 RS01455
gene id: 153493:H3L98_RS01455
uniprot id: A0A7D7N463
names: Similarity
messages: Belongs to the DprA/Smf family.

153493:H3L98 RS03365
gene id: 153493:H3L98_RS03365
uniprot id: A0A7D7N0N3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

153493:H3L98 RS04825
gene id: 153493:H3L98_RS04825
uniprot id: A0A7D7N3K5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

153493:H3L98 RS09285
gene id: 153493:H3L98_RS09285
uniprot id: A0A7D7S751
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

153493:H3L98 RS02000
gene id: 153493:H3L98_RS02000
uniprot id: A0A3P2AAJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

153493:H3L98 RS08680
gene id: 153493:H3L98_RS08680
uniprot id: A0A7D7RD65
names: Subcellular Location Annotation
messages: Membrane

153493:H3L98 RS10665
gene id: 153493:H3L98_RS10665
uniprot id: A0A3P2A698
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

153493:H3L98 RS05485
gene id: 153493:H3L98_RS05485
uniprot id: A0A7D7N179
names: Similarity
messages: Belongs to the polysaccharide synthase family.

153493:H3L98 RS03375
gene id: 153493:H3L98_RS03375
uniprot id: A0A7D7MVM7
names: Subcellular Location Annotation
messages: Membrane

153493:H3L98 RS10660
gene id: 153493:H3L98_RS10660
uniprot id: A0A7D7N3W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

153493:H3L98 RS06650
gene id: 153493:H3L98_RS06650
uniprot id: A0A7D7MWQ6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS03105
gene id: 153493:H3L98_RS03105
uniprot id: A0A7D7N2C3
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

153493:H3L98 RS10675
gene id: 153493:H3L98_RS10675
uniprot id: A0A7D7MYI9
names: Subcellular Location Annotation
messages: Membrane

153493:H3L98 RS05295
gene id: 153493:H3L98_RS05295
uniprot id: A0A7D7RMC4
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

153493:H3L98 RS06315
gene id: 153493:H3L98_RS06315
uniprot id: A0A7D7RCN7
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

153493:H3L98 RS04775
gene id: 153493:H3L98_RS04775
uniprot id: A0A3P2A598
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

153493:H3L98 RS00755
gene id: 153493:H3L98_RS00755
uniprot id: A0A7D7S089
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

153493:H3L98 RS06780
gene id: 153493:H3L98_RS06780
uniprot id: A0A3P2AA90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

153493:H3L98 RS07665
gene id: 153493:H3L98_RS07665
uniprot id: A0A7D7RCY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

153493:H3L98 RS02335
gene id: 153493:H3L98_RS02335
uniprot id: A0A7D7S0I4
names: Similarity
messages: Belongs to the GARS family.

153493:H3L98 RS04595
gene id: 153493:H3L98_RS04595
uniprot id: A0A3P2A5N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

153493:H3L98 RS09095
gene id: 153493:H3L98_RS09095
uniprot id: A0A7D7N236
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

153493:H3L98 RS02145
gene id: 153493:H3L98_RS02145
uniprot id: A0A7D7MYZ4
names: Subcellular Location Annotation
messages: Membrane

153493:H3L98 RS03805
gene id: 153493:H3L98_RS03805
uniprot id: A0A3P2A509
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

153493:H3L98 RS03270
gene id: 153493:H3L98_RS03270
uniprot id: A0A7D7MYA0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

153493:H3L98 RS08875
gene id: 153493:H3L98_RS08875
uniprot id: A0A7D7MY19
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

153493:H3L98 RS06035
gene id: 153493:H3L98_RS06035
uniprot id: A0A7D7S689
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

153493:H3L98 RS01925
gene id: 153493:H3L98_RS01925
uniprot id: A0A7D7N0B2
names: Subcellular Location Annotation
messages: Membrane

153493:H3L98 RS01985
gene id: 153493:H3L98_RS01985
uniprot id: A0A7D7S0G6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

153493:H3L98 RS05845
gene id: 153493:H3L98_RS05845
uniprot id: A0A7D7N1B7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS01865
gene id: 153493:H3L98_RS01865
uniprot id: A0A3P2A567
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

153493:H3L98 RS03350
gene id: 153493:H3L98_RS03350
uniprot id: A0A3P2A0Z8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS05100
gene id: 153493:H3L98_RS05100
uniprot id: A0A7D7S6Q8
names: Subcellular Location Annotation
messages: Membrane

153493:H3L98 RS07580
gene id: 153493:H3L98_RS07580
uniprot id: A0A7D7RV03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

153493:H3L98 RS07965
gene id: 153493:H3L98_RS07965
uniprot id: A0A7D7N167
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

153493:H3L98 RS04540
gene id: 153493:H3L98_RS04540
uniprot id: A0A7D7MW02
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

153493:H3L98 RS07260
gene id: 153493:H3L98_RS07260
uniprot id: A0A7D7SEV4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

153493:H3L98 RS10650
gene id: 153493:H3L98_RS10650
uniprot id: A0A7D7S7H5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

153493:H3L98 RS06015
gene id: 153493:H3L98_RS06015
uniprot id: A0A3P2AC34
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

153493:H3L98 RS06525
gene id: 153493:H3L98_RS06525
uniprot id: A0A7D7N0S0
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

153493:H3L98 RS05580
gene id: 153493:H3L98_RS05580
uniprot id: A0A7D7N5F7
names: Similarity
messages: Belongs to the HepT RNase toxin family.

153493:H3L98 RS05640
gene id: 153493:H3L98_RS05640
uniprot id: A0A7D7N5K3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

153493:H3L98 RS08135
gene id: 153493:H3L98_RS08135
uniprot id: A0A7D7RV47
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

153493:H3L98 RS09280
gene id: 153493:H3L98_RS09280
uniprot id: A0A7D7RZW1
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Belongs to the trans-sulfuration enzymes family.

153493:H3L98 RS05190
gene id: 153493:H3L98_RS05190
uniprot id: A0A7D7RMB5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

153493:H3L98 RS07255
gene id: 153493:H3L98_RS07255
uniprot id: A0A7D7S468
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

153493:H3L98 RS03120
gene id: 153493:H3L98_RS03120
uniprot id: A0A7D7MY91
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

153493:H3L98 RS04360
gene id: 153493:H3L98_RS04360
uniprot id: A0A7D7RM42
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

153493:H3L98 RS07535
gene id: 153493:H3L98_RS07535
uniprot id: A0A7D7N106
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

153493:H3L98 RS02540
gene id: 153493:H3L98_RS02540
uniprot id: A0A7D7MWT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

153493:H3L98 RS05735
gene id: 153493:H3L98_RS05735
uniprot id: A0A7D7N1B0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

153493:H3L98 RS01675
gene id: 153493:H3L98_RS01675
uniprot id: A0A7D7SFY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

153493:H3L98 RS07820
gene id: 153493:H3L98_RS07820
uniprot id: A0A7D7RZ13
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

153493:H3L98 RS06045
gene id: 153493:H3L98_RS06045
uniprot id: A0A7D7N2I3
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

153493:H3L98 RS07815
gene id: 153493:H3L98_RS07815
uniprot id: A0A7D7SF20
names: Similarity
messages: Belongs to the RutC family.

153493:H3L98 RS00480
gene id: 153493:H3L98_RS00480
uniprot id: A0A7D7RDT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

153493:H3L98 RS07070
gene id: 153493:H3L98_RS07070
uniprot id: A0A7D7MYR1
names: Subcellular Location Annotation
messages: Membrane

153493:H3L98 RS09615
gene id: 153493:H3L98_RS09615
uniprot id: A0A7D7T025
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

153493:H3L98 RS01980
gene id: 153493:H3L98_RS01980
uniprot id: A0A3P2A6T3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

153493:H3L98 RS08125
gene id: 153493:H3L98_RS08125
uniprot id: A0A3P2A4K0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

153493:H3L98 RS08335
gene id: 153493:H3L98_RS08335
uniprot id: A0A7D7RD28
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

153493:H3L98 RS09135
gene id: 153493:H3L98_RS09135
uniprot id: A0A7D7RKU4
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

153493:H3L98 RS04645
gene id: 153493:H3L98_RS04645
uniprot id: A0A7D7T0W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

153493:H3L98 RS09150
gene id: 153493:H3L98_RS09150
uniprot id: A0A7D7S745
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
messages: Homodimer.

153493:H3L98 RS03030
gene id: 153493:H3L98_RS03030
uniprot id: A0A7D7MUQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

153493:H3L98 RS08670
gene id: 153493:H3L98_RS08670
uniprot id: A0A7D7MUG2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

153493:H3L98 RS06770
gene id: 153493:H3L98_RS06770
uniprot id: A0A7D7MT16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

153493:H3L98 RS06410
gene id: 153493:H3L98_RS06410
uniprot id: A0A7D7MYK0
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

153493:H3L98 RS00965
gene id: 153493:H3L98_RS00965
uniprot id: A0A3P2A5T6
names: Similarity
messages: Belongs to the band 7/mec-2 family.

153493:H3L98 RS06505
gene id: 153493:H3L98_RS06505
uniprot id: A0A7D7N2M4
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

153493:H3L98 RS03345
gene id: 153493:H3L98_RS03345
uniprot id: A0A7D7N2J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

153493:H3L98 RS06125
gene id: 153493:H3L98_RS06125
uniprot id: A0A7D7S3T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

153493:H3L98 RS06625
gene id: 153493:H3L98_RS06625
uniprot id: A0A7D7N1G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

153493:H3L98 RS00490
gene id: 153493:H3L98_RS00490
uniprot id: A0A7D7RLA0
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 104 family.
messages: Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes.

153493:H3L98 RS01360
gene id: 153493:H3L98_RS01360
uniprot id: A0A7D7N1Y1
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

153493:H3L98 RS09670
gene id: 153493:H3L98_RS09670
uniprot id: A0A7D7MVZ8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

153493:H3L98 RS03815
gene id: 153493:H3L98_RS03815
uniprot id: A0A7D7N2I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

153493:H3L98 RS07005
gene id: 153493:H3L98_RS07005
uniprot id: A0A7D7RUR0
names: Subcellular Location Annotation
messages: Membrane

153493:H3L98 RS06665
gene id: 153493:H3L98_RS06665
uniprot id: A0A7D7RKB0
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

153493:H3L98 RS05830
gene id: 153493:H3L98_RS05830
uniprot id: A0A7D7N2F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

153493:H3L98 RS00865
gene id: 153493:H3L98_RS00865
uniprot id: A0A3P2A0E3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

153493:H3L98 RS09570
gene id: 153493:H3L98_RS09570
uniprot id: A0A7D7RKZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

153493:H3L98 RS03095
gene id: 153493:H3L98_RS03095
uniprot id: A0A7D7N2Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

153493:H3L98 RS01820
gene id: 153493:H3L98_RS01820
uniprot id: A0A7D7N219
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

153493:H3L98 RS06530
gene id: 153493:H3L98_RS06530
uniprot id: A0A7D7MYK8
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

153493:H3L98 RS01165
gene id: 153493:H3L98_RS01165
uniprot id: A0A7D7RDX5
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

153493:H3L98 RS06280
gene id: 153493:H3L98_RS06280
uniprot id: A0A7D7N1E5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS05425
gene id: 153493:H3L98_RS05425
uniprot id: A0A7D7S913
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

153493:H3L98 RS09900
gene id: 153493:H3L98_RS09900
uniprot id: A0A7D7MUR9
names: Subcellular Location Annotation
messages: Membrane

153493:H3L98 RS09490
gene id: 153493:H3L98_RS09490
uniprot id: A0A7D7RZX7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

153493:H3L98 RS03070
gene id: 153493:H3L98_RS03070
uniprot id: A0A7D7S0N1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

153493:H3L98 RS07315
gene id: 153493:H3L98_RS07315
uniprot id: A0A7D7N0Y4
names: Similarity
messages: Belongs to the DEAD box helicase family.

153493:H3L98 RS04965
gene id: 153493:H3L98_RS04965
uniprot id: A0A7D7RYN7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

153493:H3L98 RS01765
gene id: 153493:H3L98_RS01765
uniprot id: A0A3P2A588
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

153493:H3L98 RS08165
gene id: 153493:H3L98_RS08165
uniprot id: A0A7D7S6R5
names: Similarity
messages: Belongs to the UPF0246 family.

153493:H3L98 RS05160
gene id: 153493:H3L98_RS05160
uniprot id: A0A7D7N2U5
names: Similarity
messages: Belongs to the ArsC family.

153493:H3L98 RS03915
gene id: 153493:H3L98_RS03915
uniprot id: A0A7D7N2P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

153493:H3L98 RS04795
gene id: 153493:H3L98_RS04795
uniprot id: A0A7D7N103
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

153493:H3L98 RS01030
gene id: 153493:H3L98_RS01030
uniprot id: A0A7D7MV50
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

153493:H3L98 RS02480
gene id: 153493:H3L98_RS02480
uniprot id: A0A7D7S7Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

153493:H3L98 RS06585
gene id: 153493:H3L98_RS06585
uniprot id: A0A7D7S3V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

153493:H3L98 RS06105
gene id: 153493:H3L98_RS06105
uniprot id: A0A7D7MST2
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

153493:H3L98 RS00435
gene id: 153493:H3L98_RS00435
uniprot id: A0A7D7N3Y9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein.
messages: Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.

153493:H3L98 RS00425
gene id: 153493:H3L98_RS00425
uniprot id: A0A7D7T094
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

153493:H3L98 RS02170
gene id: 153493:H3L98_RS02170
uniprot id: A0A7D7RE98
names: Similarity
messages: Belongs to the nitroreductase family.

153493:H3L98 RS03440
gene id: 153493:H3L98_RS03440
uniprot id: A0A3P2A289
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

153493:H3L98 RS03170
gene id: 153493:H3L98_RS03170
uniprot id: A0A7D7SGA2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

153493:H3L98 RS09825
gene id: 153493:H3L98_RS09825
uniprot id: A0A7D7RXD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

153493:H3L98 RS02625
gene id: 153493:H3L98_RS02625
uniprot id: A0A7D7MZ27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

153493:H3L98 RS01785
gene id: 153493:H3L98_RS01785
uniprot id: A0A3P2A6S2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

153493:H3L98 RS09620
gene id: 153493:H3L98_RS09620
uniprot id: A0A7D7N3I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

153493:H3L98 RS02395
gene id: 153493:H3L98_RS02395
uniprot id: A0A7D7MVI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

153493:H3L98 RS07570
gene id: 153493:H3L98_RS07570
uniprot id: A0A7D7MT93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

153493:H3L98 RS02315
gene id: 153493:H3L98_RS02315
uniprot id: A0A7D7S861
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

153493:H3L98 RS08500
gene id: 153493:H3L98_RS08500
uniprot id: A0A7D7SF69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

153493:H3L98 RS00115
gene id: 153493:H3L98_RS00115
uniprot id: A0A7D7RU79
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

153493:H3L98 RS09735
gene id: 153493:H3L98_RS09735
uniprot id: A0A7D7T031
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

153493:H3L98 RS06850
gene id: 153493:H3L98_RS06850
uniprot id: A0A3P2A8G2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

153493:H3L98 RS01880
gene id: 153493:H3L98_RS01880
uniprot id: A0A7D7SG07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

153493:H3L98 RS09040
gene id: 153493:H3L98_RS09040
uniprot id: A0A3P2A673
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

153493:H3L98 RS02555
gene id: 153493:H3L98_RS02555
uniprot id: A0A3P2A178
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

153493:H3L98 RS07345
gene id: 153493:H3L98_RS07345
uniprot id: A0A7D7MVA4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

153493:H3L98 RS08650
gene id: 153493:H3L98_RS08650
uniprot id: A0A7D7N1Z7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

153493:H3L98 RS03835
gene id: 153493:H3L98_RS03835
uniprot id: A0A7D7REL8
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

153493:H3L98 RS08595
gene id: 153493:H3L98_RS08595
uniprot id: A0A7D7RV91
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

153493:H3L98 RS01515
gene id: 153493:H3L98_RS01515
uniprot id: A0A7D7MUC2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

153493:H3L98 RS02935
gene id: 153493:H3L98_RS02935
uniprot id: A0A7D7SG83
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

153493:H3L98 RS01780
gene id: 153493:H3L98_RS01780
uniprot id: A0A3P2A5I0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

153493:H3L98 RS04430
gene id: 153493:H3L98_RS04430
uniprot id: A0A7D7N2N2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

153493:H3L98 RS05800
gene id: 153493:H3L98_RS05800
uniprot id: A0A7D7RWD0
names: Similarity
messages: Belongs to the UPF0758 family.

153493:H3L98 RS05345
gene id: 153493:H3L98_RS05345
uniprot id: A0A3P2ACG1
names: Similarity
messages: Belongs to the UPF0145 family.

153493:H3L98 RS06790
gene id: 153493:H3L98_RS06790
uniprot id: A0A7D7S3X3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

153493:H3L98 RS09080
gene id: 153493:H3L98_RS09080
uniprot id: A0A3P2A6D1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

153493:H3L98 RS03965
gene id: 153493:H3L98_RS03965
uniprot id: A0A3P2A3I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

153493:H3L98 RS02415
gene id: 153493:H3L98_RS02415
uniprot id: A0A7D7RLN5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

153493:H3L98 RS09950
gene id: 153493:H3L98_RS09950
uniprot id: A0A7D7S4Y3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

153493:H3L98 RS02570
gene id: 153493:H3L98_RS02570
uniprot id: A0A7D7S877
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS05250
gene id: 153493:H3L98_RS05250
uniprot id: A0A7D7N3E1
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

153493:H3L98 RS07850
gene id: 153493:H3L98_RS07850
uniprot id: A0A7D7N157
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

153493:H3L98 RS04395
gene id: 153493:H3L98_RS04395
uniprot id: A0A7D7S0W8
names: Similarity
messages: Belongs to the UPF0102 family.

153493:H3L98 RS09805
gene id: 153493:H3L98_RS09805
uniprot id: A0A7D7MVL4
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

153493:H3L98 RS10115
gene id: 153493:H3L98_RS10115
uniprot id: A0A7D7MYD6
names: Similarity
messages: Belongs to the glutathione peroxidase family.

153493:H3L98 RS08005
gene id: 153493:H3L98_RS08005
uniprot id: A0A7D7MVM3
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

153493:H3L98 RS01000
gene id: 153493:H3L98_RS01000
uniprot id: A0A7D7N434
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

153493:H3L98 RS02920
gene id: 153493:H3L98_RS02920
uniprot id: A0A7D7S8A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

153493:H3L98 RS04065
gene id: 153493:H3L98_RS04065
uniprot id: A0A7D7MVX0
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

153493:H3L98 RS07800
gene id: 153493:H3L98_RS07800
uniprot id: A0A7D7RWU7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

153493:H3L98 RS08210
gene id: 153493:H3L98_RS08210
uniprot id: A0A3P2A5V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

153493:H3L98 RS03355
gene id: 153493:H3L98_RS03355
uniprot id: A0A7D7MZ84
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

153493:H3L98 RS10580
gene id: 153493:H3L98_RS10580
uniprot id: A0A7D7MXL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

153493:H3L98 RS03395
gene id: 153493:H3L98_RS03395
uniprot id: A0A7D7MX28
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

153493:H3L98 RS05415
gene id: 153493:H3L98_RS05415
uniprot id: A0A7D7RX81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

153493:H3L98 RS01590
gene id: 153493:H3L98_RS01590
uniprot id: A0A7D7T0F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

153493:H3L98 RS07470
gene id: 153493:H3L98_RS07470
uniprot id: A0A7D7MT83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

153493:H3L98 RS00860
gene id: 153493:H3L98_RS00860
uniprot id: A0A7D7S5E2
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

153493:H3L98 RS02670
gene id: 153493:H3L98_RS02670
uniprot id: A0A7D7RWJ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

153493:H3L98 RS01795
gene id: 153493:H3L98_RS01795
uniprot id: A0A3P2A6W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

153493:H3L98 RS04235
gene id: 153493:H3L98_RS04235
uniprot id: A0A7D7MV05
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

153493:H3L98 RS10135
gene id: 153493:H3L98_RS10135
uniprot id: A0A7D7MXI0
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

153493:H3L98 RS05760
gene id: 153493:H3L98_RS05760
uniprot id: A0A3P2AC91
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

153493:H3L98 RS03645
gene id: 153493:H3L98_RS03645
uniprot id: A0A7D7RYD8
names: Similarity
messages: Belongs to the UPF0250 family.

153493:H3L98 RS03925
gene id: 153493:H3L98_RS03925
uniprot id: A0A7D7MZD1
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

153493:H3L98 RS09465
gene id: 153493:H3L98_RS09465
uniprot id: A0A7D7RVJ4
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

153493:H3L98 RS08225
gene id: 153493:H3L98_RS08225
uniprot id: A0A7D7MVP1
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Homodimer.

153493:H3L98 RS01290
gene id: 153493:H3L98_RS01290
uniprot id: A0A7D7MUA1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

153493:H3L98 RS00985
gene id: 153493:H3L98_RS00985
uniprot id: A0A3P2A0U7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

153493:H3L98 RS05180
gene id: 153493:H3L98_RS05180
uniprot id: A0A7D7REW8
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

153493:H3L98 RS07025
gene id: 153493:H3L98_RS07025
uniprot id: A0A7D7SET3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

153493:H3L98 RS10700
gene id: 153493:H3L98_RS10700
uniprot id: A0A7D7MUY9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

153493:H3L98 RS00455
gene id: 153493:H3L98_RS00455
uniprot id: A0A7D7MYK6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

153493:H3L98 RS02875
gene id: 153493:H3L98_RS02875
uniprot id: A0A7D7MVK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

153493:H3L98 RS09505
gene id: 153493:H3L98_RS09505
uniprot id: A0A7D7T021
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

153493:H3L98 RS04255
gene id: 153493:H3L98_RS04255
uniprot id: A0A7D7RYI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

153493:H3L98 RS08960
gene id: 153493:H3L98_RS08960
uniprot id: A0A7D7N3A3
names: Similarity
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.

153493:H3L98 RS01850
gene id: 153493:H3L98_RS01850
uniprot id: A0A3P2A6K4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

153493:H3L98 RS06965
gene id: 153493:H3L98_RS06965
uniprot id: A0A7D7N0V9
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

153493:H3L98 RS09725
gene id: 153493:H3L98_RS09725
uniprot id: A0A7D7RZZ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

153493:H3L98 RS08810
gene id: 153493:H3L98_RS08810
uniprot id: A0A7D7RKR9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

153493:H3L98 RS03505
gene id: 153493:H3L98_RS03505
uniprot id: A0A7D7MYB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

153493:H3L98 RS07515
gene id: 153493:H3L98_RS07515
uniprot id: A0A7D7N2Y7
names: Function
names: Similarity
messages: Belongs to the GMC oxidoreductase family.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.

153493:H3L98 RS00915
gene id: 153493:H3L98_RS00915
uniprot id: A0A7D7MV41
names: Subcellular Location Annotation
messages: Membrane

153493:H3L98 RS00795
gene id: 153493:H3L98_RS00795
uniprot id: A0A7D7MZV0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS05165
gene id: 153493:H3L98_RS05165
uniprot id: A0A7D7N140
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS01500
gene id: 153493:H3L98_RS01500
uniprot id: A0A7D7RDZ8
names: Similarity
messages: Belongs to the peptidase M1 family.

153493:H3L98 RS03035
gene id: 153493:H3L98_RS03035
uniprot id: A0A7D7RWM7
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

153493:H3L98 RS09205
gene id: 153493:H3L98_RS09205
uniprot id: A0A7D7MY49
names: Similarity
messages: Belongs to the pyruvate kinase family.

153493:H3L98 RS02640
gene id: 153493:H3L98_RS02640
uniprot id: A0A7D7MVJ8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

153493:H3L98 RS08380
gene id: 153493:H3L98_RS08380
uniprot id: A0A7D7S4G0
names: Subcellular Location Annotation
messages: Membrane

153493:H3L98 RS06810
gene id: 153493:H3L98_RS06810
uniprot id: A0A7D7S6G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

153493:H3L98 RS10610
gene id: 153493:H3L98_RS10610
uniprot id: A0A7D7MU05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

153493:H3L98 RS06725
gene id: 153493:H3L98_RS06725
uniprot id: A0A7D7N1H6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

153493:H3L98 RS09485
gene id: 153493:H3L98_RS09485
uniprot id: A0A7D7SFE5
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS05835
gene id: 153493:H3L98_RS05835
uniprot id: A0A3P2A741
names: Subcellular Location Annotation
messages: Membrane

153493:H3L98 RS00745
gene id: 153493:H3L98_RS00745
uniprot id: A0A7D7S5D3
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

153493:H3L98 RS10740
gene id: 153493:H3L98_RS10740
uniprot id: A0A7D7RXM1
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

153493:H3L98 RS03420
gene id: 153493:H3L98_RS03420
uniprot id: A0A7D7RYB6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

153493:H3L98 RS07640
gene id: 153493:H3L98_RS07640
uniprot id: A0A7D7MXP0
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

153493:H3L98 RS05005
gene id: 153493:H3L98_RS05005
uniprot id: A0A7D7N2X2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

153493:H3L98 RS10050
gene id: 153493:H3L98_RS10050
uniprot id: A0A7D7MTW8
names: Subcellular Location Annotation
messages: Membrane

153493:H3L98 RS08505
gene id: 153493:H3L98_RS08505
uniprot id: A0A7D7RZQ1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS02225
gene id: 153493:H3L98_RS02225
uniprot id: A0A7D7SG35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Slam family.
messages: Cell outer membrane
messages: Membrane

153493:H3L98 RS06330
gene id: 153493:H3L98_RS06330
uniprot id: A0A3P2A6W1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

153493:H3L98 RS07265
gene id: 153493:H3L98_RS07265
uniprot id: A0A7D7RZB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

153493:H3L98 RS09325
gene id: 153493:H3L98_RS09325
uniprot id: A0A3P2A6V1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

153493:H3L98 RS08010
gene id: 153493:H3L98_RS08010
uniprot id: A0A7D7RKK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

153493:H3L98 RS03290
gene id: 153493:H3L98_RS03290
uniprot id: A0A7D7MUS5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

153493:H3L98 RS06695
gene id: 153493:H3L98_RS06695
uniprot id: A0A7D7SEQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

153493:H3L98 RS03710
gene id: 153493:H3L98_RS03710
uniprot id: A0A3P2A3F7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

153493:H3L98 RS03410
gene id: 153493:H3L98_RS03410
uniprot id: A0A7D7RWQ8
names: Subcellular Location Annotation
messages: Membrane

153493:H3L98 RS03265
gene id: 153493:H3L98_RS03265
uniprot id: A0A3P2A536
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

153493:H3L98 RS06295
gene id: 153493:H3L98_RS06295
uniprot id: A0A7D7MYI8
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

153493:H3L98 RS07830
gene id: 153493:H3L98_RS07830
uniprot id: A0A7D7RZF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

153493:H3L98 RS09625
gene id: 153493:H3L98_RS09625
uniprot id: A0A7D7N1M5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

153493:H3L98 RS10445
gene id: 153493:H3L98_RS10445
uniprot id: A0A7D7MYH0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

153493:H3L98 RS05655
gene id: 153493:H3L98_RS05655
uniprot id: A0A7D7RXA0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

153493:H3L98 RS10120
gene id: 153493:H3L98_RS10120
uniprot id: A0A3P2A447
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

153493:H3L98 RS00665
gene id: 153493:H3L98_RS00665
uniprot id: A0A3P2A2Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

153493:H3L98 RS03190
gene id: 153493:H3L98_RS03190
uniprot id: A0A7D7T0P2
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS04425
gene id: 153493:H3L98_RS04425
uniprot id: A0A3P2A3P6
names: Subcellular Location Annotation
messages: Cytoplasm

153493:H3L98 RS09990
gene id: 153493:H3L98_RS09990
uniprot id: A0A7D7N1Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

153493:H3L98 RS02950
gene id: 153493:H3L98_RS02950
uniprot id: A0A7D7T0N3
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS09100
gene id: 153493:H3L98_RS09100
uniprot id: A0A3P2A7H5
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

153493:H3L98 RS09300
gene id: 153493:H3L98_RS09300
uniprot id: A0A3P2A6Z9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

153493:H3L98 RS08515
gene id: 153493:H3L98_RS08515
uniprot id: A0A7D7SZW6
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

153493:H3L98 RS07000
gene id: 153493:H3L98_RS07000
uniprot id: A0A7D7MT37
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

153493:H3L98 RS08470
gene id: 153493:H3L98_RS08470
uniprot id: A0A3P2A5X3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

153493:H3L98 RS07755
gene id: 153493:H3L98_RS07755
uniprot id: A0A3P2A958
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS04500
gene id: 153493:H3L98_RS04500
uniprot id: A0A7D7S8G7
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

153493:H3L98 RS08355
gene id: 153493:H3L98_RS08355
uniprot id: A0A7D7RKN0
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

153493:H3L98 RS09335
gene id: 153493:H3L98_RS09335
uniprot id: A0A7D7MXA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

153493:H3L98 RS02160
gene id: 153493:H3L98_RS02160
uniprot id: A0A7D7MVH2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

153493:H3L98 RS01480
gene id: 153493:H3L98_RS01480
uniprot id: A0A7D7N1Z5
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

153493:H3L98 RS08925
gene id: 153493:H3L98_RS08925
uniprot id: A0A3P2A7R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

153493:H3L98 RS05110
gene id: 153493:H3L98_RS05110
uniprot id: A0A7D7S108
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

153493:H3L98 RS02195
gene id: 153493:H3L98_RS02195
uniprot id: A0A7D7RWF0
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

153493:H3L98 RS07510
gene id: 153493:H3L98_RS07510
uniprot id: A0A7D7SZR0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Binds 2 potassium ions per subunit.
messages: Dimer of dimers.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS09675
gene id: 153493:H3L98_RS09675
uniprot id: A0A3P2A5Y4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

153493:H3L98 RS01810
gene id: 153493:H3L98_RS01810
uniprot id: A0A3P2AAH0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

153493:H3L98 RS02915
gene id: 153493:H3L98_RS02915
uniprot id: A0A7D7RWL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

153493:H3L98 RS02905
gene id: 153493:H3L98_RS02905
uniprot id: A0A7D7RLR7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

153493:H3L98 RS06240
gene id: 153493:H3L98_RS06240
uniprot id: A0A7D7S6B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

153493:H3L98 RS00150
gene id: 153493:H3L98_RS00150
uniprot id: A0A7D7SZF4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

153493:H3L98 RS09455
gene id: 153493:H3L98_RS09455
uniprot id: A0A3P2A8Z3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

153493:H3L98 RS02120
gene id: 153493:H3L98_RS02120
uniprot id: A0A7D7S7X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

153493:H3L98 RS05600
gene id: 153493:H3L98_RS05600
uniprot id: A0A7D7MZU7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

153493:H3L98 RS07200
gene id: 153493:H3L98_RS07200
uniprot id: A0A7D7MYS0
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

153493:H3L98 RS05355
gene id: 153493:H3L98_RS05355
uniprot id: A0A7D7N300
names: Similarity
messages: Belongs to the polysaccharide synthase family.

153493:H3L98 RS06925
gene id: 153493:H3L98_RS06925
uniprot id: A0A3P2A831
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS05665
gene id: 153493:H3L98_RS05665
uniprot id: A0A7D7RYU5
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

153493:H3L98 RS00565
gene id: 153493:H3L98_RS00565
uniprot id: A0A3P2A208
names: Subcellular Location Annotation
messages: Cytoplasm

153493:H3L98 RS09645
gene id: 153493:H3L98_RS09645
uniprot id: A0A7D7MZD4
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.

153493:H3L98 RS02050
gene id: 153493:H3L98_RS02050
uniprot id: A0A7D7N0C0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

153493:H3L98 RS01020
gene id: 153493:H3L98_RS01020
uniprot id: A0A7D7N1V2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

153493:H3L98 RS03260
gene id: 153493:H3L98_RS03260
uniprot id: A0A7D7N0M0
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

153493:H3L98 RS04225
gene id: 153493:H3L98_RS04225
uniprot id: A0A7D7MXC5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS06230
gene id: 153493:H3L98_RS06230
uniprot id: A0A7D7SEN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

153493:H3L98 RS10100
gene id: 153493:H3L98_RS10100
uniprot id: A0A3P2A630
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

153493:H3L98 RS06565
gene id: 153493:H3L98_RS06565
uniprot id: A0A7D7RUI2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS08015
gene id: 153493:H3L98_RS08015
uniprot id: A0A7D7MTE2
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

153493:H3L98 RS01770
gene id: 153493:H3L98_RS01770
uniprot id: A0A3P2A5B7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

153493:H3L98 RS06395
gene id: 153493:H3L98_RS06395
uniprot id: A0A7D7N1F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

153493:H3L98 RS01300
gene id: 153493:H3L98_RS01300
uniprot id: A0A7D7S7T7
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

153493:H3L98 RS08115
gene id: 153493:H3L98_RS08115
uniprot id: A0A7D7RD12
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

153493:H3L98 RS03705
gene id: 153493:H3L98_RS03705
uniprot id: A0A7D7N2G5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

153493:H3L98 RS01205
gene id: 153493:H3L98_RS01205
uniprot id: A0A7D7SFV1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

153493:H3L98 RS05500
gene id: 153493:H3L98_RS05500
uniprot id: A0A3P2A7B7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

153493:H3L98 RS03470
gene id: 153493:H3L98_RS03470
uniprot id: A0A7D7N2L1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

153493:H3L98 RS03295
gene id: 153493:H3L98_RS03295
uniprot id: A0A7D7N353
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

153493:H3L98 RS02105
gene id: 153493:H3L98_RS02105
uniprot id: A0A7D7S5R7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

153493:H3L98 RS04170
gene id: 153493:H3L98_RS04170
uniprot id: A0A3P2A2V3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS04910
gene id: 153493:H3L98_RS04910
uniprot id: A0A7D7N119
names: Similarity
messages: Belongs to the peptidase M16 family.

153493:H3L98 RS08295
gene id: 153493:H3L98_RS08295
uniprot id: A0A7D7N1A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

153493:H3L98 RS04330
gene id: 153493:H3L98_RS04330
uniprot id: A0A7D7N0W8
names: Similarity
messages: Belongs to the RutC family.

153493:H3L98 RS01115
gene id: 153493:H3L98_RS01115
uniprot id: A0A7D7T0C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

153493:H3L98 RS06545
gene id: 153493:H3L98_RS06545
uniprot id: A0A3P2A9S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

153493:H3L98 RS00120
gene id: 153493:H3L98_RS00120
uniprot id: A0A7D7S6B0
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

153493:H3L98 RS00355
gene id: 153493:H3L98_RS00355
uniprot id: A0A7D7MUZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

153493:H3L98 RS01595
gene id: 153493:H3L98_RS01595
uniprot id: A0A7D7N477
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

153493:H3L98 RS10755
gene id: 153493:H3L98_RS10755
uniprot id: A0A3P2A2U4
names: Similarity
messages: Belongs to the UPF0434 family.

153493:H3L98 RS08170
gene id: 153493:H3L98_RS08170
uniprot id: A0A3P2A9R5
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

153493:H3L98 RS08675
gene id: 153493:H3L98_RS08675
uniprot id: A0A7D7MX58
names: Subcellular Location Annotation
messages: Cytoplasm

153493:H3L98 RS04535
gene id: 153493:H3L98_RS04535
uniprot id: A0A7D7N0Y8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

153493:H3L98 RS05225
gene id: 153493:H3L98_RS05225
uniprot id: A0A7D7S116
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

153493:H3L98 RS10720
gene id: 153493:H3L98_RS10720
uniprot id: A0A7D7RL84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

153493:H3L98 RS06400
gene id: 153493:H3L98_RS06400
uniprot id: A0A3P2A6U1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

153493:H3L98 RS09865
gene id: 153493:H3L98_RS09865
uniprot id: A0A7D7N1P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

153493:H3L98 RS09090
gene id: 153493:H3L98_RS09090
uniprot id: A0A7D7N1G5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

153493:H3L98 RS05135
gene id: 153493:H3L98_RS05135
uniprot id: A0A7D7T0Y8
names: Similarity
messages: Belongs to the HSP15 family.

153493:H3L98 RS09690
gene id: 153493:H3L98_RS09690
uniprot id: A0A7D7MTT6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS03895
gene id: 153493:H3L98_RS03895
uniprot id: A0A7D7T0S8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

153493:H3L98 RS01995
gene id: 153493:H3L98_RS01995
uniprot id: A0A7D7T0I0
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

153493:H3L98 RS01705
gene id: 153493:H3L98_RS01705
uniprot id: A0A3P2A5G9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

153493:H3L98 RS01085
gene id: 153493:H3L98_RS01085
uniprot id: A0A3P2A5N3
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

153493:H3L98 RS06235
gene id: 153493:H3L98_RS06235
uniprot id: A0A7D7RZ19
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

153493:H3L98 RS00825
gene id: 153493:H3L98_RS00825
uniprot id: A0A7D7RDV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

153493:H3L98 RS09330
gene id: 153493:H3L98_RS09330
uniprot id: A0A7D7N3P4
names: Similarity
messages: Belongs to the peptidase U62 family.

153493:H3L98 RS09640
gene id: 153493:H3L98_RS09640
uniprot id: A0A7D7N1G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

153493:H3L98 RS10140
gene id: 153493:H3L98_RS10140
uniprot id: A0A7D7RDM8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS07875
gene id: 153493:H3L98_RS07875
uniprot id: A0A7D7MU79
names: Subcellular Location Annotation
messages: Membrane

153493:H3L98 RS06425
gene id: 153493:H3L98_RS06425
uniprot id: A0A7D7RCP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Membrane

153493:H3L98 RS02040
gene id: 153493:H3L98_RS02040
uniprot id: A0A7D7MYY1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

153493:H3L98 RS01230
gene id: 153493:H3L98_RS01230
uniprot id: A0A7D7N234
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

153493:H3L98 RS05945
gene id: 153493:H3L98_RS05945
uniprot id: A0A7D7N2H0
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

153493:H3L98 RS03210
gene id: 153493:H3L98_RS03210
uniprot id: A0A3P2A5G2
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

153493:H3L98 RS02685
gene id: 153493:H3L98_RS02685
uniprot id: A0A7D7RY63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Homotetramer.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

153493:H3L98 RS02285
gene id: 153493:H3L98_RS02285
uniprot id: A0A7D7MY41
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

153493:H3L98 RS02410
gene id: 153493:H3L98_RS02410
uniprot id: A0A7D7MWS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

153493:H3L98 RS08865
gene id: 153493:H3L98_RS08865
uniprot id: A0A7D7N1E6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

153493:H3L98 RS01860
gene id: 153493:H3L98_RS01860
uniprot id: A0A3P2AAF9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

153493:H3L98 RS06155
gene id: 153493:H3L98_RS06155
uniprot id: A0A7D7N0R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

153493:H3L98 RS04180
gene id: 153493:H3L98_RS04180
uniprot id: A0A7D7N371
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

153493:H3L98 RS00610
gene id: 153493:H3L98_RS00610
uniprot id: A0A7D7RLA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinone-dependent D-lactate dehydrogenase family.
messages: Catalyzes the oxidation of D-lactate to pyruvate.
messages: Cell inner membrane

153493:H3L98 RS07870
gene id: 153493:H3L98_RS07870
uniprot id: A0A7D7MYX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

153493:H3L98 RS00135
gene id: 153493:H3L98_RS00135
uniprot id: A0A7D7SEI7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

153493:H3L98 RS06495
gene id: 153493:H3L98_RS06495
uniprot id: A0A7D7S6D6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

153493:H3L98 RS08095
gene id: 153493:H3L98_RS08095
uniprot id: A0A7D7MYZ7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

153493:H3L98 RS01940
gene id: 153493:H3L98_RS01940
uniprot id: A0A7D7RE79
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

153493:H3L98 RS02605
gene id: 153493:H3L98_RS02605
uniprot id: A0A7D7T0L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

153493:H3L98 RS02835
gene id: 153493:H3L98_RS02835
uniprot id: A0A7D7T0M6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

153493:H3L98 RS01740
gene id: 153493:H3L98_RS01740
uniprot id: A0A3P2A5A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

153493:H3L98 RS00850
gene id: 153493:H3L98_RS00850
uniprot id: A0A7D7S7Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

153493:H3L98 RS09815
gene id: 153493:H3L98_RS09815
uniprot id: A0A7D7RVN3
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

153493:H3L98 RS07955
gene id: 153493:H3L98_RS07955
uniprot id: A0A7D7SZT5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

153493:H3L98 RS07080
gene id: 153493:H3L98_RS07080
uniprot id: A0A7D7MU07
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

153493:H3L98 RS06085
gene id: 153493:H3L98_RS06085
uniprot id: A0A3P2A6Z6
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

153493:H3L98 RS08805
gene id: 153493:H3L98_RS08805
uniprot id: A0A7D7MVT9
names: Similarity
messages: Belongs to the YciI family.

153493:H3L98 RS02045
gene id: 153493:H3L98_RS02045
uniprot id: A0A7D7N240
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

153493:H3L98 RS07285
gene id: 153493:H3L98_RS07285
uniprot id: A0A7D7MWD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

153493:H3L98 RS04350
gene id: 153493:H3L98_RS04350
uniprot id: A0A3P2A5X0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

153493:H3L98 RS09580
gene id: 153493:H3L98_RS09580
uniprot id: A0A7D7RVK5
names: Similarity
messages: Belongs to the fabD family.

153493:H3L98 RS09360
gene id: 153493:H3L98_RS09360
uniprot id: A0A7D7RVH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

153493:H3L98 RS00505
gene id: 153493:H3L98_RS00505
uniprot id: A0A7D7S7M3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

153493:H3L98 RS07530
gene id: 153493:H3L98_RS07530
uniprot id: A0A7D7MXN0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

153493:H3L98 RS10615
gene id: 153493:H3L98_RS10615
uniprot id: A0A7D7RVX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

153493:H3L98 RS01090
gene id: 153493:H3L98_RS01090
uniprot id: A0A7D7SFT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

153493:H3L98 RS10210
gene id: 153493:H3L98_RS10210
uniprot id: A0A7D7N2B9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

153493:H3L98 RS04985
gene id: 153493:H3L98_RS04985
uniprot id: A0A7D7S8K2
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

153493:H3L98 RS07805
gene id: 153493:H3L98_RS07805
uniprot id: A0A7D7S4B5
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

153493:H3L98 RS05060
gene id: 153493:H3L98_RS05060
uniprot id: A0A3P2A4N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

153493:H3L98 RS09720
gene id: 153493:H3L98_RS09720
uniprot id: A0A7D7SFG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

153493:H3L98 RS06040
gene id: 153493:H3L98_RS06040
uniprot id: A0A7D7SZI0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

153493:H3L98 RS01035
gene id: 153493:H3L98_RS01035
uniprot id: A0A7D7MVB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

153493:H3L98 RS01375
gene id: 153493:H3L98_RS01375
uniprot id: A0A7D7MXW8
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

153493:H3L98 RS05495
gene id: 153493:H3L98_RS05495
uniprot id: A0A7D7S703
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

153493:H3L98 RS08835
gene id: 153493:H3L98_RS08835
uniprot id: A0A3P2A7M5
names: Cofactor
messages: Can also use Mn(2+) ion.

153493:H3L98 RS03300
gene id: 153493:H3L98_RS03300
uniprot id: A0A7D7RWP7
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

153493:H3L98 RS06205
gene id: 153493:H3L98_RS06205
uniprot id: A0A7D7MSU0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

153493:H3L98 RS04845
gene id: 153493:H3L98_RS04845
uniprot id: A0A7D7RYM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

153493:H3L98 RS02585
gene id: 153493:H3L98_RS02585
uniprot id: A0A7D7S5V8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

153493:H3L98 RS05490
gene id: 153493:H3L98_RS05490
uniprot id: A0A7D7RZ01
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS06670
gene id: 153493:H3L98_RS06670
uniprot id: A0A7D7MSX6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS01340
gene id: 153493:H3L98_RS01340
uniprot id: A0A3P2A7C9
names: Similarity
messages: Belongs to the SlyX family.

153493:H3L98 RS04715
gene id: 153493:H3L98_RS04715
uniprot id: A0A7D7S8Q2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

153493:H3L98 RS04990
gene id: 153493:H3L98_RS04990
uniprot id: A0A7D7T0Y1
names: Function
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane
messages: Periplasm
messages: Transfers electrons from cytochrome c551 to cytochrome oxidase.

153493:H3L98 RS07240
gene id: 153493:H3L98_RS07240
uniprot id: A0A7D7RUX0
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

153493:H3L98 RS01060
gene id: 153493:H3L98_RS01060
uniprot id: A0A7D7MU78
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

153493:H3L98 RS03060
gene id: 153493:H3L98_RS03060
uniprot id: A0A7D7S604
names: Similarity
messages: Belongs to the Smg family.

153493:H3L98 RS07995
gene id: 153493:H3L98_RS07995
uniprot id: A0A7D7MWY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

153493:H3L98 RS04270
gene id: 153493:H3L98_RS04270
uniprot id: A0A7D7RYZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

153493:H3L98 RS01620
gene id: 153493:H3L98_RS01620
uniprot id: A0A7D7N091
names: Similarity
messages: Belongs to the plasmid replication initiation factor family.

153493:H3L98 RS02355
gene id: 153493:H3L98_RS02355
uniprot id: A0A7D7N4E8
names: Similarity
messages: Belongs to the DEAD box helicase family.

153493:H3L98 RS09370
gene id: 153493:H3L98_RS09370
uniprot id: A0A7D7RX92
names: Similarity
messages: Belongs to the peptidase S41A family.

153493:H3L98 RS01555
gene id: 153493:H3L98_RS01555
uniprot id: A0A7D7RXX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

153493:H3L98 RS06745
gene id: 153493:H3L98_RS06745
uniprot id: A0A7D7MTX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

153493:H3L98 RS06380
gene id: 153493:H3L98_RS06380
uniprot id: A0A7D7SZJ9
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

153493:H3L98 RS02610
gene id: 153493:H3L98_RS02610
uniprot id: A0A7D7N4H1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS08240
gene id: 153493:H3L98_RS08240
uniprot id: A0A7D7RV54
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

153493:H3L98 RS06390
gene id: 153493:H3L98_RS06390
uniprot id: A0A7D7N0T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

153493:H3L98 RS01170
gene id: 153493:H3L98_RS01170
uniprot id: A0A7D7MWE9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

153493:H3L98 RS06620
gene id: 153493:H3L98_RS06620
uniprot id: A0A7D7N0W1
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

153493:H3L98 RS06915
gene id: 153493:H3L98_RS06915
uniprot id: A0A7D7RWM0
names: Similarity
messages: Belongs to the pirin family.

153493:H3L98 RS08520
gene id: 153493:H3L98_RS08520
uniprot id: A0A7D7N372
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

153493:H3L98 RS00895
gene id: 153493:H3L98_RS00895
uniprot id: A0A7D7N2K9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

153493:H3L98 RS06855
gene id: 153493:H3L98_RS06855
uniprot id: A0A7D7MWS1
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

153493:H3L98 RS10590
gene id: 153493:H3L98_RS10590
uniprot id: A0A7D7MW75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Membrane

153493:H3L98 RS00485
gene id: 153493:H3L98_RS00485
uniprot id: A0A7D7MW98
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

153493:H3L98 RS05395
gene id: 153493:H3L98_RS05395
uniprot id: A0A7D7MXT8
names: Subcellular Location Annotation
messages: Membrane

153493:H3L98 RS06435
gene id: 153493:H3L98_RS06435
uniprot id: A0A3P2A8N3
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

153493:H3L98 RS04480
gene id: 153493:H3L98_RS04480
uniprot id: A0A7D7RYK0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

153493:H3L98 RS05795
gene id: 153493:H3L98_RS05795
uniprot id: A0A7D7S6D0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

153493:H3L98 RS03405
gene id: 153493:H3L98_RS03405
uniprot id: A0A7D7MUT5
names: Similarity
messages: Belongs to the LOG family.

153493:H3L98 RS01805
gene id: 153493:H3L98_RS01805
uniprot id: A0A7D7N286
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

153493:H3L98 RS03950
gene id: 153493:H3L98_RS03950
uniprot id: A0A7D7REN1
names: Similarity
messages: Belongs to the peptidase M16 family.

153493:H3L98 RS08575
gene id: 153493:H3L98_RS08575
uniprot id: A0A3P2A9V7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

153493:H3L98 RS01830
gene id: 153493:H3L98_RS01830
uniprot id: A0A7D7MVF4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

153493:H3L98 RS09245
gene id: 153493:H3L98_RS09245
uniprot id: A0A7D7RKX7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

153493:H3L98 RS04160
gene id: 153493:H3L98_RS04160
uniprot id: A0A7D7S8E7
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

153493:H3L98 RS03050
gene id: 153493:H3L98_RS03050
uniprot id: A0A7D7RY90
names: Similarity
messages: Belongs to the catalase family.

153493:H3L98 RS07395
gene id: 153493:H3L98_RS07395
uniprot id: A0A3P2ADP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

153493:H3L98 RS04000
gene id: 153493:H3L98_RS04000
uniprot id: A0A7D7S8D6
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

153493:H3L98 RS04400
gene id: 153493:H3L98_RS04400
uniprot id: A0A7D7S8F9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

153493:H3L98 RS05660
gene id: 153493:H3L98_RS05660
uniprot id: A0A3P2A766
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

153493:H3L98 RS04185
gene id: 153493:H3L98_RS04185
uniprot id: A0A7D7MZF0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

153493:H3L98 RS02150
gene id: 153493:H3L98_RS02150
uniprot id: A0A7D7N246
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

153493:H3L98 RS05715
gene id: 153493:H3L98_RS05715
uniprot id: A0A7D7MZV7
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

153493:H3L98 RS08150
gene id: 153493:H3L98_RS08150
uniprot id: A0A3P2A676
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

153493:H3L98 RS05115
gene id: 153493:H3L98_RS05115
uniprot id: A0A7D7S8L2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS08855
gene id: 153493:H3L98_RS08855
uniprot id: A0A7D7SZY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

153493:H3L98 RS03185
gene id: 153493:H3L98_RS03185
uniprot id: A0A7D7S837
names: Function
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane
messages: Periplasm
messages: Transfers electrons from cytochrome c551 to cytochrome oxidase.

153493:H3L98 RS01135
gene id: 153493:H3L98_RS01135
uniprot id: A0A7D7N2M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

153493:H3L98 RS08525
gene id: 153493:H3L98_RS08525
uniprot id: A0A7D7N1C1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

153493:H3L98 RS10165
gene id: 153493:H3L98_RS10165
uniprot id: A0A7D7S7E2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS08975
gene id: 153493:H3L98_RS08975
uniprot id: A0A7D7N226
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

153493:H3L98 RS07750
gene id: 153493:H3L98_RS07750
uniprot id: A0A7D7MYW8
names: Subcellular Location Annotation
messages: Membrane

153493:H3L98 RS10025
gene id: 153493:H3L98_RS10025
uniprot id: A0A7D7MXG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

153493:H3L98 RS07245
gene id: 153493:H3L98_RS07245
uniprot id: A0A3P2A7X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

153493:H3L98 RS02590
gene id: 153493:H3L98_RS02590
uniprot id: A0A7D7SG57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

153493:H3L98 RS09730
gene id: 153493:H3L98_RS09730
uniprot id: A0A7D7S796
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

153493:H3L98 RS10785
gene id: 153493:H3L98_RS10785
uniprot id: A0A7D7N2F4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

153493:H3L98 RS04435
gene id: 153493:H3L98_RS04435
uniprot id: A0A7D7N0X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

153493:H3L98 RS04800
gene id: 153493:H3L98_RS04800
uniprot id: A0A3P2A740
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

153493:H3L98 RS09155
gene id: 153493:H3L98_RS09155
uniprot id: A0A7D7RX65
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

153493:H3L98 RS09705
gene id: 153493:H3L98_RS09705
uniprot id: A0A7D7S7A0
names: Similarity
messages: Belongs to the TrpC family.

153493:H3L98 RS06475
gene id: 153493:H3L98_RS06475
uniprot id: A0A7D7RWI1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

153493:H3L98 RS07880
gene id: 153493:H3L98_RS07880
uniprot id: A0A7D7MWY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

153493:H3L98 RS06705
gene id: 153493:H3L98_RS06705
uniprot id: A0A7D7S6F6
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

153493:H3L98 RS08625
gene id: 153493:H3L98_RS08625
uniprot id: A0A7D7S6Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

153493:H3L98 RS05780
gene id: 153493:H3L98_RS05780
uniprot id: A0A7D7MSR0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

153493:H3L98 RS10155
gene id: 153493:H3L98_RS10155
uniprot id: A0A7D7MTX5
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

153493:H3L98 RS02400
gene id: 153493:H3L98_RS02400
uniprot id: A0A7D7MY47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Slam family.
messages: Cell outer membrane
messages: Membrane

153493:H3L98 RS03485
gene id: 153493:H3L98_RS03485
uniprot id: A0A7D7N2E8
names: Similarity
messages: Belongs to the opacity porin family.

153493:H3L98 RS08270
gene id: 153493:H3L98_RS08270
uniprot id: A0A7D7RZJ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

153493:H3L98 RS02255
gene id: 153493:H3L98_RS02255
uniprot id: A0A7D7N2B7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

153493:H3L98 RS06120
gene id: 153493:H3L98_RS06120
uniprot id: A0A7D7RWF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

153493:H3L98 RS03175
gene id: 153493:H3L98_RS03175
uniprot id: A0A7D7S8V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

153493:H3L98 RS06455
gene id: 153493:H3L98_RS06455
uniprot id: A0A7D7RUH3
names: Similarity
messages: Belongs to the TrpF family.

153493:H3L98 RS09200
gene id: 153493:H3L98_RS09200
uniprot id: A0A7D7N244
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

153493:H3L98 RS08900
gene id: 153493:H3L98_RS08900
uniprot id: A0A7D7RD89
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

153493:H3L98 RS03045
gene id: 153493:H3L98_RS03045
uniprot id: A0A7D7S8B3
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

153493:H3L98 RS03310
gene id: 153493:H3L98_RS03310
uniprot id: A0A7D7RYA8
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

153493:H3L98 RS06095
gene id: 153493:H3L98_RS06095
uniprot id: A0A3P2A725
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

153493:H3L98 RS07865
gene id: 153493:H3L98_RS07865
uniprot id: A0A3P2A939
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

153493:H3L98 RS06715
gene id: 153493:H3L98_RS06715
uniprot id: A0A7D7N2Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Cell inner membrane
messages: Membrane

153493:H3L98 RS07975
gene id: 153493:H3L98_RS07975
uniprot id: A0A7D7MXS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

153493:H3L98 RS03680
gene id: 153493:H3L98_RS03680
uniprot id: A0A3P2A3G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

153493:H3L98 RS01885
gene id: 153493:H3L98_RS01885
uniprot id: A0A7D7S0G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

153493:H3L98 RS03480
gene id: 153493:H3L98_RS03480
uniprot id: A0A7D7MZ89
names: Similarity
messages: Belongs to the opacity porin family.

153493:H3L98 RS08200
gene id: 153493:H3L98_RS08200
uniprot id: A0A7D7N160
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

153493:H3L98 RS02460
gene id: 153493:H3L98_RS02460
uniprot id: A0A7D7RY41
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

153493:H3L98 RS09180
gene id: 153493:H3L98_RS09180
uniprot id: A0A7D7N3A6
names: Similarity
messages: Belongs to the UPF0053 family.

153493:H3L98 RS10790
gene id: 153493:H3L98_RS10790
uniprot id: A0A3P2A358
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

153493:H3L98 RS07980
gene id: 153493:H3L98_RS07980
uniprot id: A0A7D7N141
names: Similarity
messages: Belongs to the aspartokinase family.

153493:H3L98 RS06750
gene id: 153493:H3L98_RS06750
uniprot id: A0A3P2A857
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

153493:H3L98 RS01240
gene id: 153493:H3L98_RS01240
uniprot id: A0A7D7MYS1
names: Similarity
messages: Belongs to the pirin family.

153493:H3L98 RS07075
gene id: 153493:H3L98_RS07075
uniprot id: A0A7D7N5L0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

153493:H3L98 RS08000
gene id: 153493:H3L98_RS08000
uniprot id: A0A3P2A4K5
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

153493:H3L98 RS09650
gene id: 153493:H3L98_RS09650
uniprot id: A0A7D7MUP5
names: Subcellular Location Annotation
messages: Membrane

153493:H3L98 RS04565
gene id: 153493:H3L98_RS04565
uniprot id: A0A7D7RM59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

153493:H3L98 RS09070
gene id: 153493:H3L98_RS09070
uniprot id: A0A7D7RZU4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

153493:H3L98 RS03460
gene id: 153493:H3L98_RS03460
uniprot id: A0A7D7N4S0
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

153493:H3L98 RS01010
gene id: 153493:H3L98_RS01010
uniprot id: A0A3P2A0S9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

153493:H3L98 RS03850
gene id: 153493:H3L98_RS03850
uniprot id: A0A7D7RM03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

153493:H3L98 RS03810
gene id: 153493:H3L98_RS03810
uniprot id: A0A7D7MZB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

153493:H3L98 RS04285
gene id: 153493:H3L98_RS04285
uniprot id: A0A7D7S0V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

153493:H3L98 RS06170
gene id: 153493:H3L98_RS06170
uniprot id: A0A7D7N0P6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

153493:H3L98 RS07190
gene id: 153493:H3L98_RS07190
uniprot id: A0A7D7MXK9
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

153493:H3L98 RS09630
gene id: 153493:H3L98_RS09630
uniprot id: A0A7D7N285
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

153493:H3L98 RS04870
gene id: 153493:H3L98_RS04870
uniprot id: A0A7D7S8J1
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

153493:H3L98 RS09790
gene id: 153493:H3L98_RS09790
uniprot id: A0A7D7RDJ9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

153493:H3L98 RS04205
gene id: 153493:H3L98_RS04205
uniprot id: A0A7D7N0V6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

153493:H3L98 RS07355
gene id: 153493:H3L98_RS07355
uniprot id: A0A7D7MT75
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

153493:H3L98 RS08735
gene id: 153493:H3L98_RS08735
uniprot id: A0A7D7RZR4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

153493:H3L98 RS06885
gene id: 153493:H3L98_RS06885
uniprot id: A0A7D7MT23
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

153493:H3L98 RS09020
gene id: 153493:H3L98_RS09020
uniprot id: A0A7D7MVV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

153493:H3L98 RS10760
gene id: 153493:H3L98_RS10760
uniprot id: A0A7D7S7I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

153493:H3L98 RS05980
gene id: 153493:H3L98_RS05980
uniprot id: A0A7D7MWJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

153493:H3L98 RS04580
gene id: 153493:H3L98_RS04580
uniprot id: A0A3P2A276
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

153493:H3L98 RS08990
gene id: 153493:H3L98_RS08990
uniprot id: A0A7D7N1C0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

153493:H3L98 RS08985
gene id: 153493:H3L98_RS08985
uniprot id: A0A7D7MY30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

153493:H3L98 RS06150
gene id: 153493:H3L98_RS06150
uniprot id: A0A3P2A6S6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

153493:H3L98 RS03275
gene id: 153493:H3L98_RS03275
uniprot id: A0A7D7REH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

153493:H3L98 RS09910
gene id: 153493:H3L98_RS09910
uniprot id: A0A7D7RDL2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

153493:H3L98 RS09470
gene id: 153493:H3L98_RS09470
uniprot id: A0A7D7S779
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

153493:H3L98 RS03455
gene id: 153493:H3L98_RS03455
uniprot id: A0A7D7T0Q4
names: Similarity
messages: Belongs to the YkuD family.

153493:H3L98 RS05050
gene id: 153493:H3L98_RS05050
uniprot id: A0A7D7MW39
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

153493:H3L98 RS01200
gene id: 153493:H3L98_RS01200
uniprot id: A0A7D7S5H5
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

153493:H3L98 RS06365
gene id: 153493:H3L98_RS06365
uniprot id: A0A7D7SEP0
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

153493:H3L98 RS04240
gene id: 153493:H3L98_RS04240
uniprot id: A0A7D7S900
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

153493:H3L98 RS03870
gene id: 153493:H3L98_RS03870
uniprot id: A0A3P2A3N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

153493:H3L98 RS03390
gene id: 153493:H3L98_RS03390
uniprot id: A0A7D7REI0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

153493:H3L98 RS09405
gene id: 153493:H3L98_RS09405
uniprot id: A0A7D7N3F4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

153493:H3L98 RS06645
gene id: 153493:H3L98_RS06645
uniprot id: A0A7D7MTW1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

153493:H3L98 RS08775
gene id: 153493:H3L98_RS08775
uniprot id: A0A7D7MUG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

153493:H3L98 RS02165
gene id: 153493:H3L98_RS02165
uniprot id: A0A7D7MY32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

153493:H3L98 RS05535
gene id: 153493:H3L98_RS05535
uniprot id: A0A7D7RX93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane
messages: Homododecamer. Tetramer of trimer.
messages: Required for type IV pilus biogenesis and competence. Could function as a pore for exit of the pilus but also as a channel for entry of heme and antimicrobial agents and uptake of transforming DNA.

153493:H3L98 RS02265
gene id: 153493:H3L98_RS02265
uniprot id: A0A7D7MZ03
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

153493:H3L98 RS10705
gene id: 153493:H3L98_RS10705
uniprot id: A0A7D7MXM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

153493:H3L98 RS05855
gene id: 153493:H3L98_RS05855
uniprot id: A0A7D7N0M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

153493:H3L98 RS09920
gene id: 153493:H3L98_RS09920
uniprot id: A0A7D7RL29
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

153493:H3L98 RS08055
gene id: 153493:H3L98_RS08055
uniprot id: A0A3P2A4Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

153493:H3L98 RS03450
gene id: 153493:H3L98_RS03450
uniprot id: A0A7D7S855
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

153493:H3L98 RS08310
gene id: 153493:H3L98_RS08310
uniprot id: A0A7D7N357
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

153493:H3L98 RS06540
gene id: 153493:H3L98_RS06540
uniprot id: A0A3P2AAE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

153493:H3L98 RS10095
gene id: 153493:H3L98_RS10095
uniprot id: A0A3P2A2L7
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

153493:H3L98 RS08825
gene id: 153493:H3L98_RS08825
uniprot id: A0A7D7S716
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

153493:H3L98 RS04490
gene id: 153493:H3L98_RS04490
uniprot id: A0A7D7SGM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

153493:H3L98 RS09075
gene id: 153493:H3L98_RS09075
uniprot id: A0A3P2A9J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

153493:H3L98 RS00680
gene id: 153493:H3L98_RS00680
uniprot id: A0A7D7N1T1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

153493:H3L98 RS06760
gene id: 153493:H3L98_RS06760
uniprot id: A0A3P2ABV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

153493:H3L98 RS05765
gene id: 153493:H3L98_RS05765
uniprot id: A0A7D7RCH7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

153493:H3L98 RS00840
gene id: 153493:H3L98_RS00840
uniprot id: A0A7D7MU52
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

153493:H3L98 RS01725
gene id: 153493:H3L98_RS01725
uniprot id: A0A3P2A8P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.