1531429:JI75 RS02775
gene id: 1531429:JI75_RS02775
uniprot id: A0A0A8B319
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1531429:JI75 RS03960
gene id: 1531429:JI75_RS03960
uniprot id: A0A0A8B9Z9
names: Similarity
messages: Belongs to the UPF0234 family.

1531429:JI75 RS06075
gene id: 1531429:JI75_RS06075
uniprot id: A0A0A8B660
names: Similarity
messages: Belongs to the YggT family.

1531429:JI75 RS02235
gene id: 1531429:JI75_RS02235
uniprot id: A0A0A8B4F1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1531429:JI75 RS03105
gene id: 1531429:JI75_RS03105
uniprot id: A0A0A8B9J5
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1531429:JI75 RS03840
gene id: 1531429:JI75_RS03840
uniprot id: A0A0A8B3G8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1531429:JI75 RS08115
gene id: 1531429:JI75_RS08115
uniprot id: A0A0A8B771
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1531429:JI75 RS03015
gene id: 1531429:JI75_RS03015
uniprot id: A0A0A8B323
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1531429:JI75 RS03420
gene id: 1531429:JI75_RS03420
uniprot id: A0A0A8B3A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1531429:JI75 RS08110
gene id: 1531429:JI75_RS08110
uniprot id: A0A0A8BBX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1531429:JI75 RS04005
gene id: 1531429:JI75_RS04005
uniprot id: A0A0A8B3K5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1531429:JI75 RS08510
gene id: 1531429:JI75_RS08510
uniprot id: A0A0A8BC29
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1531429:JI75 RS03350
gene id: 1531429:JI75_RS03350
uniprot id: A0A0A8B9N6
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1531429:JI75 RS08260
gene id: 1531429:JI75_RS08260
uniprot id: A0A0A8BBZ6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1531429:JI75 RS04855
gene id: 1531429:JI75_RS04855
uniprot id: A0A0A8B461
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

1531429:JI75 RS01825
gene id: 1531429:JI75_RS01825
uniprot id: A0A0A8B2D0
names: Similarity
messages: Belongs to the DEAD box helicase family.

1531429:JI75 RS03790
gene id: 1531429:JI75_RS03790
uniprot id: A0A0A8B373
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1531429:JI75 RS02960
gene id: 1531429:JI75_RS02960
uniprot id: A0A0A8B349
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1531429:JI75 RS05340
gene id: 1531429:JI75_RS05340
uniprot id: A0A0A8B4D4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1531429:JI75 RS03440
gene id: 1531429:JI75_RS03440
uniprot id: A0A0A8B4X9
names: Subcellular Location Annotation
messages: Membrane

1531429:JI75 RS02655
gene id: 1531429:JI75_RS02655
uniprot id: A0A0A8B9D4
names: Similarity
messages: Belongs to the pirin family.

1531429:JI75 RS03010
gene id: 1531429:JI75_RS03010
uniprot id: A0A0A8B360
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1531429:JI75 RS01870
gene id: 1531429:JI75_RS01870
uniprot id: A0A0A8B956
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1531429:JI75 RS03415
gene id: 1531429:JI75_RS03415
uniprot id: A0A0A8B3D2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1531429:JI75 RS05180
gene id: 1531429:JI75_RS05180
uniprot id: A0A0A8B3V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

1531429:JI75 RS00825
gene id: 1531429:JI75_RS00825
uniprot id: A0A0A8B3P7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1531429:JI75 RS00555
gene id: 1531429:JI75_RS00555
uniprot id: A0A0A8B3K3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1531429:JI75 RS03095
gene id: 1531429:JI75_RS03095
uniprot id: A0A0A8B340
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1531429:JI75 RS06840
gene id: 1531429:JI75_RS06840
uniprot id: A0A0A8B4M9
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1531429:JI75 RS03215
gene id: 1531429:JI75_RS03215
uniprot id: A0A0A8B4T7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1531429:JI75 RS06855
gene id: 1531429:JI75_RS06855
uniprot id: A0A0A8B524
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1531429:JI75 RS07170
gene id: 1531429:JI75_RS07170
uniprot id: A0A0A8B584
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

1531429:JI75 RS08305
gene id: 1531429:JI75_RS08305
uniprot id: A0A0A8B495
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1531429:JI75 RS05540
gene id: 1531429:JI75_RS05540
uniprot id: A0A0A8B495
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1531429:JI75 RS03130
gene id: 1531429:JI75_RS03130
uniprot id: A0A0A8B9K0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1531429:JI75 RS08285
gene id: 1531429:JI75_RS08285
uniprot id: A0A0A8BC00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1531429:JI75 RS05690
gene id: 1531429:JI75_RS05690
uniprot id: A0A0A8BAR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1531429:JI75 RS03725
gene id: 1531429:JI75_RS03725
uniprot id: A0A0A8B3I3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1531429:JI75 RS01210
gene id: 1531429:JI75_RS01210
uniprot id: A0A0A8B3V6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1531429:JI75 RS04550
gene id: 1531429:JI75_RS04550
uniprot id: A0A0A8B5L6
names: Subcellular Location Annotation
messages: Membrane

1531429:JI75 RS03855
gene id: 1531429:JI75_RS03855
uniprot id: A0A0A8B540
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1531429:JI75 RS02610
gene id: 1531429:JI75_RS02610
uniprot id: A0A0A8B4J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1531429:JI75 RS03715
gene id: 1531429:JI75_RS03715
uniprot id: A0A0A8B515
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

1531429:JI75 RS00465
gene id: 1531429:JI75_RS00465
uniprot id: A0A0A8B3J1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1531429:JI75 RS03890
gene id: 1531429:JI75_RS03890
uniprot id: A0A0A8B3L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

1531429:JI75 RS03710
gene id: 1531429:JI75_RS03710
uniprot id: A0A0A8B9T8
names: Similarity
messages: Belongs to the ribF family.

1531429:JI75 RS02685
gene id: 1531429:JI75_RS02685
uniprot id: A0A0A8B9D7
names: Similarity
messages: Belongs to the DEAD box helicase family.

1531429:JI75 RS08530
gene id: 1531429:JI75_RS08530
uniprot id: A0A0A8B5U8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1531429:JI75 RS05555
gene id: 1531429:JI75_RS05555
uniprot id: A0A0A8B5Z3
names: Similarity
messages: Belongs to the amidinotransferase family.

1531429:JI75 RS02585
gene id: 1531429:JI75_RS02585
uniprot id: A0A0A8B2Z2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1531429:JI75 RS03340
gene id: 1531429:JI75_RS03340
uniprot id: A0A0A8B385
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1531429:JI75 RS04930
gene id: 1531429:JI75_RS04930
uniprot id: A0A0A8B3S8
names: Similarity
messages: Belongs to the ArsC family.

1531429:JI75 RS04660
gene id: 1531429:JI75_RS04660
uniprot id: A0A0A8B439
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1531429:JI75 RS07790
gene id: 1531429:JI75_RS07790
uniprot id: A0A0A8B732
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1531429:JI75 RS00530
gene id: 1531429:JI75_RS00530
uniprot id: A0A0A8B3K0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1531429:JI75 RS06860
gene id: 1531429:JI75_RS06860
uniprot id: A0A0A8B4X1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1531429:JI75 RS01725
gene id: 1531429:JI75_RS01725
uniprot id: A0A0A8B489
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1531429:JI75 RS03675
gene id: 1531429:JI75_RS03675
uniprot id: A0A0A8B351
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1531429:JI75 RS08490
gene id: 1531429:JI75_RS08490
uniprot id: A0A0A8B5E2
names: Similarity
messages: Belongs to the AOR/FOR family.

1531429:JI75 RS02695
gene id: 1531429:JI75_RS02695
uniprot id: A0A0A8B4L1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1531429:JI75 RS06750
gene id: 1531429:JI75_RS06750
uniprot id: A0A0A8B503
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1531429:JI75 RS06280
gene id: 1531429:JI75_RS06280
uniprot id: A0A0A8B4R6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1531429:JI75 RS00170
gene id: 1531429:JI75_RS00170
uniprot id: A0A0A8B1R8
names: Cofactor
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.

1531429:JI75 RS05740
gene id: 1531429:JI75_RS05740
uniprot id: A0A0A8B4J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1531429:JI75 RS06520
gene id: 1531429:JI75_RS06520
uniprot id: A0A0A8B4Q1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1531429:JI75 RS03405
gene id: 1531429:JI75_RS03405
uniprot id: A0A0A8B9P4
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1531429:JI75 RS06225
gene id: 1531429:JI75_RS06225
uniprot id: A0A0A8B4Q7
names: Similarity
messages: Belongs to the peptidase C40 family.

1531429:JI75 RS02820
gene id: 1531429:JI75_RS02820
uniprot id: A0A0A8B2P2
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1531429:JI75 RS07585
gene id: 1531429:JI75_RS07585
uniprot id: A0A0A8B534
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1531429:JI75 RS03030
gene id: 1531429:JI75_RS03030
uniprot id: A0A0A8B4Q6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1531429:JI75 RS02605
gene id: 1531429:JI75_RS02605
uniprot id: A0A0A8B9C9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1531429:JI75 RS07945
gene id: 1531429:JI75_RS07945
uniprot id: A0A0A8B5K9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1531429:JI75 RS01650
gene id: 1531429:JI75_RS01650
uniprot id: A0A0A8B2M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1531429:JI75 RS03530
gene id: 1531429:JI75_RS03530
uniprot id: A0A0A8B4Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

1531429:JI75 RS08435
gene id: 1531429:JI75_RS08435
uniprot id: A0A0A8B5D5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1531429:JI75 RS06810
gene id: 1531429:JI75_RS06810
uniprot id: A0A0A8B4V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1531429:JI75 RS04035
gene id: 1531429:JI75_RS04035
uniprot id: A0A0A8B3B6
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1531429:JI75 RS07505
gene id: 1531429:JI75_RS07505
uniprot id: A0A0A8B5H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1531429:JI75 RS02130
gene id: 1531429:JI75_RS02130
uniprot id: A0A0A8B982
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1531429:JI75 RS00115
gene id: 1531429:JI75_RS00115
uniprot id: A0A0A8B1Q7
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1531429:JI75 RS06245
gene id: 1531429:JI75_RS06245
uniprot id: A0A0A8B683
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1531429:JI75 RS04625
gene id: 1531429:JI75_RS04625
uniprot id: A0A0A8BAE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1531429:JI75 RS03250
gene id: 1531429:JI75_RS03250
uniprot id: A0A0A8B370
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1531429:JI75 RS08465
gene id: 1531429:JI75_RS08465
uniprot id: A0A0A8B5D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1531429:JI75 RS06135
gene id: 1531429:JI75_RS06135
uniprot id: A0A0A8B669
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1531429:JI75 RS05170
gene id: 1531429:JI75_RS05170
uniprot id: A0A0A8B4B1
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the nitrate reductase NapAB complex composed of NapA and NapB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.
messages: Secreted

1531429:JI75 RS03430
gene id: 1531429:JI75_RS03430
uniprot id: A0A0A8B9P9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1531429:JI75 RS03810
gene id: 1531429:JI75_RS03810
uniprot id: A0A0A8B3G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1531429:JI75 RS05630
gene id: 1531429:JI75_RS05630
uniprot id: A0A0A8B407
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1531429:JI75 RS08335
gene id: 1531429:JI75_RS08335
uniprot id: A0A0A8BC07
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1531429:JI75 RS03895
gene id: 1531429:JI75_RS03895
uniprot id: A0A0A8B3I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1531429:JI75 RS07120
gene id: 1531429:JI75_RS07120
uniprot id: A0A0A8BBH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1531429:JI75 RS01620
gene id: 1531429:JI75_RS01620
uniprot id: A0A0A8B471
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.

1531429:JI75 RS05080
gene id: 1531429:JI75_RS05080
uniprot id: A0A0A8B3U4
names: Subcellular Location Annotation
messages: Membrane

1531429:JI75 RS05130
gene id: 1531429:JI75_RS05130
uniprot id: A0A0A8B3V0
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1531429:JI75 RS08610
gene id: 1531429:JI75_RS08610
uniprot id: A0A0A8B7D8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1531429:JI75 RS04135
gene id: 1531429:JI75_RS04135
uniprot id: A0A0A8B3S1
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1531429:JI75 RS03235
gene id: 1531429:JI75_RS03235
uniprot id: A0A0A8B9L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1531429:JI75 RS00495
gene id: 1531429:JI75_RS00495
uniprot id: A0A0A8B3J6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1531429:JI75 RS03115
gene id: 1531429:JI75_RS03115
uniprot id: A0A0A8B380
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1531429:JI75 RS01010
gene id: 1531429:JI75_RS01010
uniprot id: A0A0A8B3S3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1531429:JI75 RS04095
gene id: 1531429:JI75_RS04095
uniprot id: A0A0A8BA32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1531429:JI75 RS01555
gene id: 1531429:JI75_RS01555
uniprot id: A0A0A8B463
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1531429:JI75 RS02630
gene id: 1531429:JI75_RS02630
uniprot id: A0A0A8B9D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1531429:JI75 RS03325
gene id: 1531429:JI75_RS03325
uniprot id: A0A0A8B9N1
names: Cofactor
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN covalently per subunit.

1531429:JI75 RS02200
gene id: 1531429:JI75_RS02200
uniprot id: A0A0A8B2G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1531429:JI75 RS01720
gene id: 1531429:JI75_RS01720
uniprot id: A0A0A8B941
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1531429:JI75 RS01805
gene id: 1531429:JI75_RS01805
uniprot id: A0A0A8B950
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1531429:JI75 RS01885
gene id: 1531429:JI75_RS01885
uniprot id: A0A0A8B2K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1531429:JI75 RS05575
gene id: 1531429:JI75_RS05575
uniprot id: A0A0A8BAQ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

1531429:JI75 RS03085
gene id: 1531429:JI75_RS03085
uniprot id: A0A0A8B376
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1531429:JI75 RS02735
gene id: 1531429:JI75_RS02735
uniprot id: A0A0A8B4L6
names: Subcellular Location Annotation
messages: Membrane

1531429:JI75 RS06905
gene id: 1531429:JI75_RS06905
uniprot id: A0A0A8B536
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1531429:JI75 RS04555
gene id: 1531429:JI75_RS04555
uniprot id: A0A0A8B425
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1531429:JI75 RS01530
gene id: 1531429:JI75_RS01530
uniprot id: A0A0A8B2H1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1531429:JI75 RS04540
gene id: 1531429:JI75_RS04540
uniprot id: A0A0A8B3N3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1531429:JI75 RS05220
gene id: 1531429:JI75_RS05220
uniprot id: A0A0A8B3V8
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1531429:JI75 RS03940
gene id: 1531429:JI75_RS03940
uniprot id: A0A0A8B3M4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1531429:JI75 RS05590
gene id: 1531429:JI75_RS05590
uniprot id: A0A0A8B4A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1531429:JI75 RS06375
gene id: 1531429:JI75_RS06375
uniprot id: A0A0A8B4S6
names: Similarity
messages: Belongs to the DapA family.

1531429:JI75 RS05135
gene id: 1531429:JI75_RS05135
uniprot id: A0A0A8BAK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1531429:JI75 RS05995
gene id: 1531429:JI75_RS05995
uniprot id: A0A0A8B4M8
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1531429:JI75 RS01745
gene id: 1531429:JI75_RS01745
uniprot id: A0A0A8B945
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1531429:JI75 RS06275
gene id: 1531429:JI75_RS06275
uniprot id: A0A0A8B688
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1531429:JI75 RS00850
gene id: 1531429:JI75_RS00850
uniprot id: A0A0A8B224
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1531429:JI75 RS08095
gene id: 1531429:JI75_RS08095
uniprot id: A0A0A8B5N1
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1531429:JI75 RS01915
gene id: 1531429:JI75_RS01915
uniprot id: A0A0A8B2D8
names: Similarity
messages: Belongs to the Fur family.

1531429:JI75 RS01140
gene id: 1531429:JI75_RS01140
uniprot id: A0A0A8B8T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

1531429:JI75 RS07730
gene id: 1531429:JI75_RS07730
uniprot id: A0A0A8BBT9
names: Similarity
messages: Belongs to the HypD family.

1531429:JI75 RS06895
gene id: 1531429:JI75_RS06895
uniprot id: A0A0A8BBB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1531429:JI75 RS02940
gene id: 1531429:JI75_RS02940
uniprot id: A0A0A8B2R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1531429:JI75 RS03000
gene id: 1531429:JI75_RS03000
uniprot id: A0A0A8B9H6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1531429:JI75 RS08460
gene id: 1531429:JI75_RS08460
uniprot id: A0A0A8B5M2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1531429:JI75 RS00330
gene id: 1531429:JI75_RS00330
uniprot id: A0A0A8B1U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1531429:JI75 RS03315
gene id: 1531429:JI75_RS03315
uniprot id: A0A0A8B381
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1531429:JI75 RS02885
gene id: 1531429:JI75_RS02885
uniprot id: A0A0A8B2Z7
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1531429:JI75 RS04900
gene id: 1531429:JI75_RS04900
uniprot id: A0A0A8B3S4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1531429:JI75 RS01690
gene id: 1531429:JI75_RS01690
uniprot id: A0A0A8B2B2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1531429:JI75 RS06220
gene id: 1531429:JI75_RS06220
uniprot id: A0A0A8B679
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1531429:JI75 RS03205
gene id: 1531429:JI75_RS03205
uniprot id: A0A0A8B2X4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1531429:JI75 RS07235
gene id: 1531429:JI75_RS07235
uniprot id: A0A0A8B597
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1531429:JI75 RS04715
gene id: 1531429:JI75_RS04715
uniprot id: A0A0A8B447
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1531429:JI75 RS00285
gene id: 1531429:JI75_RS00285
uniprot id: A0A0A8B8A8
names: Similarity
messages: Belongs to the UPF0237 family.

1531429:JI75 RS02970
gene id: 1531429:JI75_RS02970
uniprot id: A0A0A8B2R9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1531429:JI75 RS01080
gene id: 1531429:JI75_RS01080
uniprot id: A0A0A8B3T4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1531429:JI75 RS00690
gene id: 1531429:JI75_RS00690
uniprot id: A0A0A8B1S8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1531429:JI75 RS04065
gene id: 1531429:JI75_RS04065
uniprot id: A0A0A8B3B9
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

1531429:JI75 RS07135
gene id: 1531429:JI75_RS07135
uniprot id: A0A0A8B6P7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1531429:JI75 RS03765
gene id: 1531429:JI75_RS03765
uniprot id: A0A0A8B9V3
names: Similarity
messages: Belongs to the barstar family.

1531429:JI75 RS00950
gene id: 1531429:JI75_RS00950
uniprot id: A0A0A8B1W6
names: Subcellular Location Annotation
messages: Membrane

1531429:JI75 RS01565
gene id: 1531429:JI75_RS01565
uniprot id: A0A0A8B2H4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1531429:JI75 RS05895
gene id: 1531429:JI75_RS05895
uniprot id: A0A0A8BAU0
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1531429:JI75 RS03545
gene id: 1531429:JI75_RS03545
uniprot id: A0A0A8B332
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1531429:JI75 RS05840
gene id: 1531429:JI75_RS05840
uniprot id: A0A0A8B4K7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1531429:JI75 RS00015
gene id: 1531429:JI75_RS00015
uniprot id: A0A0A8B1T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1531429:JI75 RS01550
gene id: 1531429:JI75_RS01550
uniprot id: A0A0A8B923
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1531429:JI75 RS05875
gene id: 1531429:JI75_RS05875
uniprot id: A0A0A8B637
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1531429:JI75 RS02250
gene id: 1531429:JI75_RS02250
uniprot id: A0A0A8B2H2
names: Similarity
messages: Belongs to the class-I fumarase family.

1531429:JI75 RS02550
gene id: 1531429:JI75_RS02550
uniprot id: A0A0A8B4I7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1531429:JI75 RS06300
gene id: 1531429:JI75_RS06300
uniprot id: A0A0A8B4L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

1531429:JI75 RS07670
gene id: 1531429:JI75_RS07670
uniprot id: A0A0A8B718
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1531429:JI75 RS01125
gene id: 1531429:JI75_RS01125
uniprot id: A0A0A8B270
names: Subcellular Location Annotation
messages: Membrane

1531429:JI75 RS00165
gene id: 1531429:JI75_RS00165
uniprot id: A0A0A8B1U9
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1531429:JI75 RS05275
gene id: 1531429:JI75_RS05275
uniprot id: A0A0A8B458
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1531429:JI75 RS01230
gene id: 1531429:JI75_RS01230
uniprot id: A0A0A8B8U9
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1531429:JI75 RS07570
gene id: 1531429:JI75_RS07570
uniprot id: A0A0A8B704
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1531429:JI75 RS05110
gene id: 1531429:JI75_RS05110
uniprot id: A0A0A8BAJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1531429:JI75 RS08240
gene id: 1531429:JI75_RS08240
uniprot id: A0A0A8B784
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1531429:JI75 RS07840
gene id: 1531429:JI75_RS07840
uniprot id: A0A0A8B5E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1531429:JI75 RS02020
gene id: 1531429:JI75_RS02020
uniprot id: A0A0A8B2R7
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1531429:JI75 RS03695
gene id: 1531429:JI75_RS03695
uniprot id: A0A0A8B3H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1531429:JI75 RS00030
gene id: 1531429:JI75_RS00030
uniprot id: A0A0A8B1G3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1531429:JI75 RS00735
gene id: 1531429:JI75_RS00735
uniprot id: A0A0A8B3N5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1531429:JI75 RS04890
gene id: 1531429:JI75_RS04890
uniprot id: A0A0A8B465
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1531429:JI75 RS06680
gene id: 1531429:JI75_RS06680
uniprot id: A0A0A8B4S9
names: Subcellular Location Annotation
messages: Membrane

1531429:JI75 RS05990
gene id: 1531429:JI75_RS05990
uniprot id: A0A0A8B653
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

1531429:JI75 RS08315
gene id: 1531429:JI75_RS08315
uniprot id: A0A0A8B797
names: Subcellular Location Annotation
messages: Membrane

1531429:JI75 RS05580
gene id: 1531429:JI75_RS05580
uniprot id: A0A0A8B5Z7
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1531429:JI75 RS03220
gene id: 1531429:JI75_RS03220
uniprot id: A0A0A8B3A0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1531429:JI75 RS08290
gene id: 1531429:JI75_RS08290
uniprot id: A0A0A8B793
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1531429:JI75 RS00960
gene id: 1531429:JI75_RS00960
uniprot id: A0A0A8B8P8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1531429:JI75 RS04085
gene id: 1531429:JI75_RS04085
uniprot id: A0A0A8B3M1
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1531429:JI75 RS04045
gene id: 1531429:JI75_RS04045
uniprot id: A0A0A8B580
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1531429:JI75 RS06675
gene id: 1531429:JI75_RS06675
uniprot id: A0A0A8B4Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1531429:JI75 RS03175
gene id: 1531429:JI75_RS03175
uniprot id: A0A0A8B2W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1531429:JI75 RS05660
gene id: 1531429:JI75_RS05660
uniprot id: A0A0A8B411
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1531429:JI75 RS00945
gene id: 1531429:JI75_RS00945
uniprot id: A0A0A8B243
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1531429:JI75 RS02255
gene id: 1531429:JI75_RS02255
uniprot id: A0A0A8B996
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1531429:JI75 RS05425
gene id: 1531429:JI75_RS05425
uniprot id: A0A0A8B5X7
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1531429:JI75 RS00565
gene id: 1531429:JI75_RS00565
uniprot id: A0A0A8B1X8
names: Subcellular Location Annotation
messages: Membrane

1531429:JI75 RS04805
gene id: 1531429:JI75_RS04805
uniprot id: A0A0A8BAG4
names: Subcellular Location Annotation
messages: Membrane

1531429:JI75 RS01220
gene id: 1531429:JI75_RS01220
uniprot id: A0A0A8B288
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1531429:JI75 RS04020
gene id: 1531429:JI75_RS04020
uniprot id: A0A0A8B574
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1531429:JI75 RS05715
gene id: 1531429:JI75_RS05715
uniprot id: A0A0A8B4C4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1531429:JI75 RS07635
gene id: 1531429:JI75_RS07635
uniprot id: A0A0A8B712
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1531429:JI75 RS03690
gene id: 1531429:JI75_RS03690
uniprot id: A0A0A8B511
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1531429:JI75 RS06365
gene id: 1531429:JI75_RS06365
uniprot id: A0A0A8BB04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1531429:JI75 RS06925
gene id: 1531429:JI75_RS06925
uniprot id: A0A0A8B6K9
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1531429:JI75 RS01400
gene id: 1531429:JI75_RS01400
uniprot id: A0A0A8B401
names: Subcellular Location Annotation
messages: Cytoplasm

1531429:JI75 RS03870
gene id: 1531429:JI75_RS03870
uniprot id: A0A0A8B3H4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1531429:JI75 RS00840
gene id: 1531429:JI75_RS00840
uniprot id: A0A0A8B259
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1531429:JI75 RS05265
gene id: 1531429:JI75_RS05265
uniprot id: A0A0A8B5V9
names: Similarity
messages: Belongs to the CobT family.

1531429:JI75 RS02975
gene id: 1531429:JI75_RS02975
uniprot id: A0A0A8B9H2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1531429:JI75 RS06175
gene id: 1531429:JI75_RS06175
uniprot id: A0A0A8B493
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1531429:JI75 RS07330
gene id: 1531429:JI75_RS07330
uniprot id: A0A0A8BBM0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1531429:JI75 RS07185
gene id: 1531429:JI75_RS07185
uniprot id: A0A0A8BBI7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1531429:JI75 RS04835
gene id: 1531429:JI75_RS04835
uniprot id: A0A0A8B3R6
names: Subcellular Location Annotation
messages: Membrane

1531429:JI75 RS01310
gene id: 1531429:JI75_RS01310
uniprot id: A0A0A8B2A7
names: Subcellular Location Annotation
messages: Membrane

1531429:JI75 RS00715
gene id: 1531429:JI75_RS00715
uniprot id: A0A0A8B208
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1531429:JI75 RS00315
gene id: 1531429:JI75_RS00315
uniprot id: A0A0A8B8B3
names: Similarity
messages: Belongs to the TelA family.

1531429:JI75 RS03780
gene id: 1531429:JI75_RS03780
uniprot id: A0A0A8B3J3
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1531429:JI75 RS06250
gene id: 1531429:JI75_RS06250
uniprot id: A0A0A8B4R2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1531429:JI75 RS01265
gene id: 1531429:JI75_RS01265
uniprot id: A0A0A8B3W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1531429:JI75 RS06590
gene id: 1531429:JI75_RS06590
uniprot id: A0A0A8B4X2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

1531429:JI75 RS00370
gene id: 1531429:JI75_RS00370
uniprot id: A0A0A8B3H7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1531429:JI75 RS06835
gene id: 1531429:JI75_RS06835
uniprot id: A0A0A8B4W5
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1531429:JI75 RS06915
gene id: 1531429:JI75_RS06915
uniprot id: A0A0A8B4P4
names: Similarity
messages: Belongs to the ETF-QO/FixC family.

1531429:JI75 RS00610
gene id: 1531429:JI75_RS00610
uniprot id: A0A0A8B227
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1531429:JI75 RS06510
gene id: 1531429:JI75_RS06510
uniprot id: A0A0A8B6C8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1531429:JI75 RS03935
gene id: 1531429:JI75_RS03935
uniprot id: A0A0A8B558
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1531429:JI75 RS01730
gene id: 1531429:JI75_RS01730
uniprot id: A0A0A8B2N7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1531429:JI75 RS08320
gene id: 1531429:JI75_RS08320
uniprot id: A0A0A8B5R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1531429:JI75 RS01240
gene id: 1531429:JI75_RS01240
uniprot id: A0A0A8B2C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1531429:JI75 RS01520
gene id: 1531429:JI75_RS01520
uniprot id: A0A0A8B459
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1531429:JI75 RS02915
gene id: 1531429:JI75_RS02915
uniprot id: A0A0A8B2Q8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1531429:JI75 RS00460
gene id: 1531429:JI75_RS00460
uniprot id: A0A0A8B8E8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1531429:JI75 RS02900
gene id: 1531429:JI75_RS02900
uniprot id: A0A0A8B4N7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1531429:JI75 RS03155
gene id: 1531429:JI75_RS03155
uniprot id: A0A0A8B9K4
names: Similarity
messages: Belongs to the asp23 family.

1531429:JI75 RS07360
gene id: 1531429:JI75_RS07360
uniprot id: A0A0A8B4Y0
names: Similarity
messages: Belongs to the DtxR/MntR family.

1531429:JI75 RS07805
gene id: 1531429:JI75_RS07805
uniprot id: A0A0A8B5E4
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1531429:JI75 RS08430
gene id: 1531429:JI75_RS08430
uniprot id: A0A0A8B5L7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1531429:JI75 RS03195
gene id: 1531429:JI75_RS03195
uniprot id: A0A0A8B359
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1531429:JI75 RS01100
gene id: 1531429:JI75_RS01100
uniprot id: A0A0A8B1Y8
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

1531429:JI75 RS07090
gene id: 1531429:JI75_RS07090
uniprot id: A0A0A8BBG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Membrane

1531429:JI75 RS01385
gene id: 1531429:JI75_RS01385
uniprot id: A0A0A8B2C7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1531429:JI75 RS04970
gene id: 1531429:JI75_RS04970
uniprot id: A0A0A8B477
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1531429:JI75 RS07485
gene id: 1531429:JI75_RS07485
uniprot id: A0A0A8B5A6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1531429:JI75 RS03610
gene id: 1531429:JI75_RS03610
uniprot id: A0A0A8B502
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1531429:JI75 RS03025
gene id: 1531429:JI75_RS03025
uniprot id: A0A0A8B9I2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1531429:JI75 RS04195
gene id: 1531429:JI75_RS04195
uniprot id: A0A0A8BA50
names: Similarity
messages: Belongs to the UPF0102 family.

1531429:JI75 RS08325
gene id: 1531429:JI75_RS08325
uniprot id: A0A0A8B5J9
names: Similarity
messages: Belongs to the peptidase M18 family.

1531429:JI75 RS05845
gene id: 1531429:JI75_RS05845
uniprot id: A0A0A8B4E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1531429:JI75 RS02140
gene id: 1531429:JI75_RS02140
uniprot id: A0A0A8B2T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1531429:JI75 RS01985
gene id: 1531429:JI75_RS01985
uniprot id: A0A0A8B2R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

1531429:JI75 RS04115
gene id: 1531429:JI75_RS04115
uniprot id: A0A0A8B3C8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1531429:JI75 RS04075
gene id: 1531429:JI75_RS04075
uniprot id: A0A0A8B585
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1531429:JI75 RS00110
gene id: 1531429:JI75_RS00110
uniprot id: A0A0A8B1U0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1531429:JI75 RS07195
gene id: 1531429:JI75_RS07195
uniprot id: A0A0A8B591
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

1531429:JI75 RS00970
gene id: 1531429:JI75_RS00970
uniprot id: A0A0A8B279
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1531429:JI75 RS06265
gene id: 1531429:JI75_RS06265
uniprot id: A0A0A8BAY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1531429:JI75 RS06500
gene id: 1531429:JI75_RS06500
uniprot id: A0A0A8B4F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

1531429:JI75 RS00730
gene id: 1531429:JI75_RS00730
uniprot id: A0A0A8B8K8
names: Similarity
messages: Belongs to the Fur family.

1531429:JI75 RS06260
gene id: 1531429:JI75_RS06260
uniprot id: A0A0A8B4B0
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1531429:JI75 RS01365
gene id: 1531429:JI75_RS01365
uniprot id: A0A0A8B245
names: Subcellular Location Annotation
messages: Membrane

1531429:JI75 RS05270
gene id: 1531429:JI75_RS05270
uniprot id: A0A0A8B4C5
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1531429:JI75 RS03560
gene id: 1531429:JI75_RS03560
uniprot id: A0A0A8B3F5
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1531429:JI75 RS03600
gene id: 1531429:JI75_RS03600
uniprot id: A0A0A8B342
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1531429:JI75 RS06950
gene id: 1531429:JI75_RS06950
uniprot id: A0A0A8B6L6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1531429:JI75 RS04470
gene id: 1531429:JI75_RS04470
uniprot id: A0A0A8B404
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

1531429:JI75 RS01270
gene id: 1531429:JI75_RS01270
uniprot id: A0A0A8B2D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1531429:JI75 RS07980
gene id: 1531429:JI75_RS07980
uniprot id: A0A0A8B5F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1531429:JI75 RS06165
gene id: 1531429:JI75_RS06165
uniprot id: A0A0A8B4Q0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1531429:JI75 RS08310
gene id: 1531429:JI75_RS08310
uniprot id: A0A0A8BC02
names: Similarity
messages: Belongs to the carbamate kinase family.

1531429:JI75 RS06050
gene id: 1531429:JI75_RS06050
uniprot id: A0A0A8B656
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

1531429:JI75 RS04675
gene id: 1531429:JI75_RS04675
uniprot id: A0A0A8B3P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1531429:JI75 RS04015
gene id: 1531429:JI75_RS04015
uniprot id: A0A0A8BA12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1531429:JI75 RS03905
gene id: 1531429:JI75_RS03905
uniprot id: A0A0A8B9Y6
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1531429:JI75 RS06130
gene id: 1531429:JI75_RS06130
uniprot id: A0A0A8BAW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1531429:JI75 RS05245
gene id: 1531429:JI75_RS05245
uniprot id: A0A0A8B3W2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1531429:JI75 RS01375
gene id: 1531429:JI75_RS01375
uniprot id: A0A0A8B3Z6
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1531429:JI75 RS08005
gene id: 1531429:JI75_RS08005
uniprot id: A0A0A8B5L9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1531429:JI75 RS02910
gene id: 1531429:JI75_RS02910
uniprot id: A0A0A8B302
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1531429:JI75 RS00790
gene id: 1531429:JI75_RS00790
uniprot id: A0A0A8B254
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1531429:JI75 RS02920
gene id: 1531429:JI75_RS02920
uniprot id: A0A0A8B9G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1531429:JI75 RS08220
gene id: 1531429:JI75_RS08220
uniprot id: A0A0A8B5I4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1531429:JI75 RS08345
gene id: 1531429:JI75_RS08345
uniprot id: A0A0A8B5S3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1531429:JI75 RS03785
gene id: 1531429:JI75_RS03785
uniprot id: A0A0A8B3F8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1531429:JI75 RS02100
gene id: 1531429:JI75_RS02100
uniprot id: A0A0A8B2F4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1531429:JI75 RS07915
gene id: 1531429:JI75_RS07915
uniprot id: A0A0A8B573
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1531429:JI75 RS03815
gene id: 1531429:JI75_RS03815
uniprot id: A0A0A8B378
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1531429:JI75 RS03920
gene id: 1531429:JI75_RS03920
uniprot id: A0A0A8B3I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1531429:JI75 RS07100
gene id: 1531429:JI75_RS07100
uniprot id: A0A0A8B575
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

1531429:JI75 RS01315
gene id: 1531429:JI75_RS01315
uniprot id: A0A0A8B230
names: Subcellular Location Annotation
messages: Membrane

1531429:JI75 RS01090
gene id: 1531429:JI75_RS01090
uniprot id: A0A0A8B296
names: Subcellular Location Annotation
messages: Cytoplasm

1531429:JI75 RS05215
gene id: 1531429:JI75_RS05215
uniprot id: A0A0A8B448
names: Similarity
messages: Belongs to the CobH/CbiC family.

1531429:JI75 RS05570
gene id: 1531429:JI75_RS05570
uniprot id: A0A0A8B3Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1531429:JI75 RS07610
gene id: 1531429:JI75_RS07610
uniprot id: A0A0A8B5I0
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1531429:JI75 RS05820
gene id: 1531429:JI75_RS05820
uniprot id: A0A0A8B4E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1531429:JI75 RS03800
gene id: 1531429:JI75_RS03800
uniprot id: A0A0A8B528
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1531429:JI75 RS07190
gene id: 1531429:JI75_RS07190
uniprot id: A0A0A8B6Q9
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

1531429:JI75 RS01225
gene id: 1531429:JI75_RS01225
uniprot id: A0A0A8B213
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1531429:JI75 RS07865
gene id: 1531429:JI75_RS07865
uniprot id: A0A0A8B5E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1531429:JI75 RS04795
gene id: 1531429:JI75_RS04795
uniprot id: A0A0A8B3R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1531429:JI75 RS02085
gene id: 1531429:JI75_RS02085
uniprot id: A0A0A8B4D1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1531429:JI75 RS04935
gene id: 1531429:JI75_RS04935
uniprot id: A0A0A8BAH9
names: Subcellular Location Annotation
messages: Membrane

1531429:JI75 RS01060
gene id: 1531429:JI75_RS01060
uniprot id: A0A0A8B290
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1531429:JI75 RS02615
gene id: 1531429:JI75_RS02615
uniprot id: A0A0A8B2Z6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1531429:JI75 RS02935
gene id: 1531429:JI75_RS02935
uniprot id: A0A0A8B308
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1531429:JI75 RS07245
gene id: 1531429:JI75_RS07245
uniprot id: A0A0A8B4V5
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1531429:JI75 RS00400
gene id: 1531429:JI75_RS00400
uniprot id: A0A0A8B8D3
names: Cofactor
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN covalently per subunit.

1531429:JI75 RS03290
gene id: 1531429:JI75_RS03290
uniprot id: A0A0A8B374
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1531429:JI75 RS02360
gene id: 1531429:JI75_RS02360
uniprot id: A0A0A8B2R2
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1531429:JI75 RS01630
gene id: 1531429:JI75_RS01630
uniprot id: A0A0A8B2H8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1531429:JI75 RS07075
gene id: 1531429:JI75_RS07075
uniprot id: A0A0A8B570
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1531429:JI75 RS02240
gene id: 1531429:JI75_RS02240
uniprot id: A0A0A8B2U7
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1531429:JI75 RS03065
gene id: 1531429:JI75_RS03065
uniprot id: A0A0A8B333
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1531429:JI75 RS06145
gene id: 1531429:JI75_RS06145
uniprot id: A0A0A8B4J0
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1531429:JI75 RS05435
gene id: 1531429:JI75_RS05435
uniprot id: A0A0A8B483
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1531429:JI75 RS06405
gene id: 1531429:JI75_RS06405
uniprot id: A0A0A8B4N1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1531429:JI75 RS06255
gene id: 1531429:JI75_RS06255
uniprot id: A0A0A8B4K9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1531429:JI75 RS00280
gene id: 1531429:JI75_RS00280
uniprot id: A0A0A8B1K2
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1531429:JI75 RS01030
gene id: 1531429:JI75_RS01030
uniprot id: A0A0A8B1X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Cell wall formation.
messages: Cytoplasm

1531429:JI75 RS04110
gene id: 1531429:JI75_RS04110
uniprot id: A0A0A8B3M6
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1531429:JI75 RS03615
gene id: 1531429:JI75_RS03615
uniprot id: A0A0A8B3G5
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

1531429:JI75 RS06890
gene id: 1531429:JI75_RS06890
uniprot id: A0A0A8B4N9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1531429:JI75 RS02985
gene id: 1531429:JI75_RS02985
uniprot id: A0A0A8B354
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1531429:JI75 RS06525
gene id: 1531429:JI75_RS06525
uniprot id: A0A0A8B4G1
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1531429:JI75 RS02860
gene id: 1531429:JI75_RS02860
uniprot id: A0A0A8B9F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1531429:JI75 RS01095
gene id: 1531429:JI75_RS01095
uniprot id: A0A0A8B265
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1531429:JI75 RS03740
gene id: 1531429:JI75_RS03740
uniprot id: A0A0A8B9U6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1531429:JI75 RS03865
gene id: 1531429:JI75_RS03865
uniprot id: A0A0A8B3K8
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1531429:JI75 RS04650
gene id: 1531429:JI75_RS04650
uniprot id: A0A0A8BAF0
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

1531429:JI75 RS06065
gene id: 1531429:JI75_RS06065
uniprot id: A0A0A8B470
names: Similarity
messages: Belongs to the UPF0235 family.

1531429:JI75 RS09320
gene id: 1531429:JI75_RS09320
uniprot id: A0A0A8B4K3
names: Similarity
messages: Belongs to the peptidase S41A family.

1531429:JI75 RS00375
gene id: 1531429:JI75_RS00375
uniprot id: A0A0A8B1Y2
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

1531429:JI75 RS07285
gene id: 1531429:JI75_RS07285
uniprot id: A0A0A8B5A7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

1531429:JI75 RS03845
gene id: 1531429:JI75_RS03845
uniprot id: A0A0A8B383
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1531429:JI75 RS07155
gene id: 1531429:JI75_RS07155
uniprot id: A0A0A8BBH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1531429:JI75 RS07875
gene id: 1531429:JI75_RS07875
uniprot id: A0A0A8B568
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1531429:JI75 RS02225
gene id: 1531429:JI75_RS02225
uniprot id: A0A0A8B2G9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

1531429:JI75 RS06885
gene id: 1531429:JI75_RS06885
uniprot id: A0A0A8B4X6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1531429:JI75 RS07785
gene id: 1531429:JI75_RS07785
uniprot id: A0A0A8BBU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1531429:JI75 RS02965
gene id: 1531429:JI75_RS02965
uniprot id: A0A0A8B313
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1531429:JI75 RS06400
gene id: 1531429:JI75_RS06400
uniprot id: A0A0A8B4T3
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1531429:JI75 RS04955
gene id: 1531429:JI75_RS04955
uniprot id: A0A0A8B3T2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1531429:JI75 RS06095
gene id: 1531429:JI75_RS06095
uniprot id: A0A0A8B475
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1531429:JI75 RS05530
gene id: 1531429:JI75_RS05530
uniprot id: A0A0A8B5Z0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1531429:JI75 RS01330
gene id: 1531429:JI75_RS01330
uniprot id: A0A0A8B2E6
names: Subcellular Location Annotation
messages: Membrane

1531429:JI75 RS06080
gene id: 1531429:JI75_RS06080
uniprot id: A0A0A8B4N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1531429:JI75 RS07030
gene id: 1531429:JI75_RS07030
uniprot id: A0A0A8BBE8
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1531429:JI75 RS00130
gene id: 1531429:JI75_RS00130
uniprot id: A0A0A8B3D4
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1531429:JI75 RS05605
gene id: 1531429:JI75_RS05605
uniprot id: A0A0A8B602
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1531429:JI75 RS01075
gene id: 1531429:JI75_RS01075
uniprot id: A0A0A8B8R7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1531429:JI75 RS06475
gene id: 1531429:JI75_RS06475
uniprot id: A0A0A8BB21
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1531429:JI75 RS05420
gene id: 1531429:JI75_RS05420
uniprot id: A0A0A8BAN3
names: Subcellular Location Annotation
messages: Membrane

1531429:JI75 RS05945
gene id: 1531429:JI75_RS05945
uniprot id: A0A0A8B4G2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1531429:JI75 RS00585
gene id: 1531429:JI75_RS00585
uniprot id: A0A0A8B221
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1531429:JI75 RS01785
gene id: 1531429:JI75_RS01785
uniprot id: A0A0A8B2P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1531429:JI75 RS01640
gene id: 1531429:JI75_RS01640
uniprot id: A0A0A8B932
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1531429:JI75 RS03335
gene id: 1531429:JI75_RS03335
uniprot id: A0A0A8B3B7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1531429:JI75 RS05535
gene id: 1531429:JI75_RS05535
uniprot id: A0A0A8BC02
names: Similarity
messages: Belongs to the carbamate kinase family.

1531429:JI75 RS06980
gene id: 1531429:JI75_RS06980
uniprot id: A0A0A8B553
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1531429:JI75 RS06445
gene id: 1531429:JI75_RS06445
uniprot id: A0A0A8BB16
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1531429:JI75 RS03820
gene id: 1531429:JI75_RS03820
uniprot id: A0A0A8B9W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1531429:JI75 RS05105
gene id: 1531429:JI75_RS05105
uniprot id: A0A0A8B3U7
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1531429:JI75 RS00925
gene id: 1531429:JI75_RS00925
uniprot id: A0A0A8B1W2
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1531429:JI75 RS01215
gene id: 1531429:JI75_RS01215
uniprot id: A0A0A8B2C3
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1531429:JI75 RS07220
gene id: 1531429:JI75_RS07220
uniprot id: A0A0A8B4U8
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1531429:JI75 RS05870
gene id: 1531429:JI75_RS05870
uniprot id: A0A0A8BAT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1531429:JI75 RS00365
gene id: 1531429:JI75_RS00365
uniprot id: A0A0A8B8C7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1531429:JI75 RS02135
gene id: 1531429:JI75_RS02135
uniprot id: A0A0A8B4D7
names: Similarity
messages: Belongs to the NAD synthetase family.

1531429:JI75 RS00670
gene id: 1531429:JI75_RS00670
uniprot id: A0A0A8B8J6
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

1531429:JI75 RS09290
gene id: 1531429:JI75_RS09290
uniprot id: A0A0A8B406
names: Similarity
messages: Belongs to the polypeptide deformylase family.

1531429:JI75 RS03240
gene id: 1531429:JI75_RS03240
uniprot id: A0A0A8B4U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1531429:JI75 RS03775
gene id: 1531429:JI75_RS03775
uniprot id: A0A0A8B523
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1531429:JI75 RS04655
gene id: 1531429:JI75_RS04655
uniprot id: A0A0A8B5N2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1531429:JI75 RS07175
gene id: 1531429:JI75_RS07175
uniprot id: A0A0A8B531
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1531429:JI75 RS00985
gene id: 1531429:JI75_RS00985
uniprot id: A0A0A8B251
names: Subcellular Location Annotation
messages: Membrane

1531429:JI75 RS04730
gene id: 1531429:JI75_RS04730
uniprot id: A0A0A8BAF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1531429:JI75 RS05455
gene id: 1531429:JI75_RS05455
uniprot id: A0A0A8B5Y2
names: Subcellular Location Annotation
messages: Membrane

1531429:JI75 RS02980
gene id: 1531429:JI75_RS02980
uniprot id: A0A0A8B4P9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1531429:JI75 RS07040
gene id: 1531429:JI75_RS07040
uniprot id: A0A0A8B564
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1531429:JI75 RS05485
gene id: 1531429:JI75_RS05485
uniprot id: A0A0A8B5Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1531429:JI75 RS08000
gene id: 1531429:JI75_RS08000
uniprot id: A0A0A8B755
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1531429:JI75 RS06960
gene id: 1531429:JI75_RS06960
uniprot id: A0A0A8B4Z2
names: Subcellular Location Annotation
messages: Membrane

1531429:JI75 RS01810
gene id: 1531429:JI75_RS01810
uniprot id: A0A0A8B4A1
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1531429:JI75 RS08100
gene id: 1531429:JI75_RS08100
uniprot id: A0A0A8B5G9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1531429:JI75 RS00260
gene id: 1531429:JI75_RS00260
uniprot id: A0A0A8B3F6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

1531429:JI75 RS03190
gene id: 1531429:JI75_RS03190
uniprot id: A0A0A8B396
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1531429:JI75 RS05450
gene id: 1531429:JI75_RS05450
uniprot id: A0A0A8BAN7
names: Subcellular Location Annotation
messages: Membrane

1531429:JI75 RS04735
gene id: 1531429:JI75_RS04735
uniprot id: A0A0A8B5P4
names: Similarity
messages: Belongs to the P(II) protein family.

1531429:JI75 RS03005
gene id: 1531429:JI75_RS03005
uniprot id: A0A0A8B4Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1531429:JI75 RS05550
gene id: 1531429:JI75_RS05550
uniprot id: A0A0A8BAP8
names: Subcellular Location Annotation
messages: Membrane

1531429:JI75 RS05100
gene id: 1531429:JI75_RS05100
uniprot id: A0A0A8B435
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1531429:JI75 RS02245
gene id: 1531429:JI75_RS02245
uniprot id: A0A0A8B2Q1
names: Similarity
messages: Belongs to the class-I fumarase family.

1531429:JI75 RS07320
gene id: 1531429:JI75_RS07320
uniprot id: A0A0A8B562
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1531429:JI75 RS04240
gene id: 1531429:JI75_RS04240
uniprot id: A0A0A8B3T9
names: Function
names: Similarity
messages: Abolishes the inhibitory effect of tetracyclin on protein synthesis by a non-covalent modification of the ribosomes.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1531429:JI75 RS07015
gene id: 1531429:JI75_RS07015
uniprot id: A0A0A8B501
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1531429:JI75 RS05545
gene id: 1531429:JI75_RS05545
uniprot id: A0A0A8B3Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

1531429:JI75 RS01120
gene id: 1531429:JI75_RS01120
uniprot id: A0A0A8B2A3
names: Similarity
messages: Belongs to the UPF0473 family.

1531429:JI75 RS01655
gene id: 1531429:JI75_RS01655
uniprot id: A0A0A8B2I2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1531429:JI75 RS00145
gene id: 1531429:JI75_RS00145
uniprot id: A0A0A8B1H9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1531429:JI75 RS05385
gene id: 1531429:JI75_RS05385
uniprot id: A0A0A8B3X6
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

1531429:JI75 RS03590
gene id: 1531429:JI75_RS03590
uniprot id: A0A0A8B3C4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1531429:JI75 RS04495
gene id: 1531429:JI75_RS04495
uniprot id: A0A0A8B5L0
names: Subcellular Location Annotation
messages: Membrane

1531429:JI75 RS03230
gene id: 1531429:JI75_RS03230
uniprot id: A0A0A8B2X9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1531429:JI75 RS06235
gene id: 1531429:JI75_RS06235
uniprot id: A0A0A8B4A4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1531429:JI75 RS00185
gene id: 1531429:JI75_RS00185
uniprot id: A0A0A8B3E4
names: Subcellular Location Annotation
messages: Membrane

1531429:JI75 RS01560
gene id: 1531429:JI75_RS01560
uniprot id: A0A0A8B2L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1531429:JI75 RS01525
gene id: 1531429:JI75_RS01525
uniprot id: A0A0A8B2L2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1531429:JI75 RS01760
gene id: 1531429:JI75_RS01760
uniprot id: A0A0A8B2J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1531429:JI75 RS07740
gene id: 1531429:JI75_RS07740
uniprot id: A0A0A8B5J3
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

1531429:JI75 RS07325
gene id: 1531429:JI75_RS07325
uniprot id: A0A0A8B4X4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1531429:JI75 RS07910
gene id: 1531429:JI75_RS07910
uniprot id: A0A0A8B5F1
names: Subcellular Location Annotation
messages: Membrane

1531429:JI75 RS01495
gene id: 1531429:JI75_RS01495
uniprot id: A0A0A8B2K7
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1531429:JI75 RS05230
gene id: 1531429:JI75_RS05230
uniprot id: A0A0A8B5V5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1531429:JI75 RS01970
gene id: 1531429:JI75_RS01970
uniprot id: A0A0A8B966
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

1531429:JI75 RS01475
gene id: 1531429:JI75_RS01475
uniprot id: A0A0A8B287
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1531429:JI75 RS03555
gene id: 1531429:JI75_RS03555
uniprot id: A0A0A8B4Z3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1531429:JI75 RS06070
gene id: 1531429:JI75_RS06070
uniprot id: A0A0A8BAV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

1531429:JI75 RS03370
gene id: 1531429:JI75_RS03370
uniprot id: A0A0A8B306
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1531429:JI75 RS00525
gene id: 1531429:JI75_RS00525
uniprot id: A0A0A8B8G1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1531429:JI75 RS06735
gene id: 1531429:JI75_RS06735
uniprot id: A0A0A8B4K6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1531429:JI75 RS07845
gene id: 1531429:JI75_RS07845
uniprot id: A0A0A8B565
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1531429:JI75 RS02045
gene id: 1531429:JI75_RS02045
uniprot id: A0A0A8B972
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1531429:JI75 RS00150
gene id: 1531429:JI75_RS00150
uniprot id: A0A0A8B892
names: Similarity
messages: Belongs to the GARS family.

1531429:JI75 RS08075
gene id: 1531429:JI75_RS08075
uniprot id: A0A0A8B5G7
names: Subcellular Location Annotation
messages: Membrane

1531429:JI75 RS01440
gene id: 1531429:JI75_RS01440
uniprot id: A0A0A8B2G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1531429:JI75 RS03750
gene id: 1531429:JI75_RS03750
uniprot id: A0A0A8B3I8
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1531429:JI75 RS07180
gene id: 1531429:JI75_RS07180
uniprot id: A0A0A8B4U1
names: Similarity
messages: Belongs to the TlyA family.

1531429:JI75 RS05880
gene id: 1531429:JI75_RS05880
uniprot id: A0A0A8B4L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1531429:JI75 RS04950
gene id: 1531429:JI75_RS04950
uniprot id: A0A0A8B418
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1531429:JI75 RS05225
gene id: 1531429:JI75_RS05225
uniprot id: A0A0A8BAL2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1531429:JI75 RS01895
gene id: 1531429:JI75_RS01895
uniprot id: A0A0A8B960
names: Subcellular Location Annotation
messages: Membrane

1531429:JI75 RS05310
gene id: 1531429:JI75_RS05310
uniprot id: A0A0A8B3W8
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1531429:JI75 RS02790
gene id: 1531429:JI75_RS02790
uniprot id: A0A0A8B9E7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1531429:JI75 RS02030
gene id: 1531429:JI75_RS02030
uniprot id: A0A0A8B2E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

1531429:JI75 RS06100
gene id: 1531429:JI75_RS06100
uniprot id: A0A0A8BAW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1531429:JI75 RS01860
gene id: 1531429:JI75_RS01860
uniprot id: A0A0A8B2K5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1531429:JI75 RS01980
gene id: 1531429:JI75_RS01980
uniprot id: A0A0A8B4B9
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1531429:JI75 RS00360
gene id: 1531429:JI75_RS00360
uniprot id: A0A0A8B1M0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

1531429:JI75 RS03655
gene id: 1531429:JI75_RS03655
uniprot id: A0A0A8B3H0
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1531429:JI75 RS05620
gene id: 1531429:JI75_RS05620
uniprot id: A0A0A8B4H5
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1531429:JI75 RS07340
gene id: 1531429:JI75_RS07340
uniprot id: A0A0A8B5C2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1531429:JI75 RS08390
gene id: 1531429:JI75_RS08390
uniprot id: A0A0A8B7B0
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1531429:JI75 RS00915
gene id: 1531429:JI75_RS00915
uniprot id: A0A0A8B268
names: Similarity
messages: Belongs to the HypE family.

1531429:JI75 RS05655
gene id: 1531429:JI75_RS05655
uniprot id: A0A0A8B4B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1531429:JI75 RS02995
gene id: 1531429:JI75_RS02995
uniprot id: A0A0A8B2S5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1531429:JI75 RS05600
gene id: 1531429:JI75_RS05600
uniprot id: A0A0A8BAQ6
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1531429:JI75 RS04745
gene id: 1531429:JI75_RS04745
uniprot id: A0A0A8B402
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1531429:JI75 RS05565
gene id: 1531429:JI75_RS05565
uniprot id: A0A0A8B4A0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1531429:JI75 RS02120
gene id: 1531429:JI75_RS02120
uniprot id: A0A0A8B2N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1531429:JI75 RS08235
gene id: 1531429:JI75_RS08235
uniprot id: A0A0A8BBZ2
names: Similarity
messages: Belongs to the asp23 family.

1531429:JI75 RS02770
gene id: 1531429:JI75_RS02770
uniprot id: A0A0A8B4M0
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1531429:JI75 RS01660
gene id: 1531429:JI75_RS01660
uniprot id: A0A0A8B2A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1531429:JI75 RS00125
gene id: 1531429:JI75_RS00125
uniprot id: A0A0A8B887
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1531429:JI75 RS05980
gene id: 1531429:JI75_RS05980
uniprot id: A0A0A8B457
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

1531429:JI75 RS04100
gene id: 1531429:JI75_RS04100
uniprot id: A0A0A8B590
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1531429:JI75 RS05480
gene id: 1531429:JI75_RS05480
uniprot id: A0A0A8BAP1
names: Similarity
messages: Belongs to the peptidase C1 family.

1531429:JI75 RS08270
gene id: 1531429:JI75_RS08270
uniprot id: A0A0A8B5Q8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

1531429:JI75 RS03395
gene id: 1531429:JI75_RS03395
uniprot id: A0A0A8B397
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1531429:JI75 RS06440
gene id: 1531429:JI75_RS06440
uniprot id: A0A0A8B4E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1531429:JI75 RS03150
gene id: 1531429:JI75_RS03150
uniprot id: A0A0A8B2W1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1531429:JI75 RS00930
gene id: 1531429:JI75_RS00930
uniprot id: A0A0A8B8P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1531429:JI75 RS00270
gene id: 1531429:JI75_RS00270
uniprot id: A0A0A8B1W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1531429:JI75 RS02930
gene id: 1531429:JI75_RS02930
uniprot id: A0A0A8B344
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1531429:JI75 RS05650
gene id: 1531429:JI75_RS05650
uniprot id: A0A0A8B4I0
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1531429:JI75 RS06320
gene id: 1531429:JI75_RS06320
uniprot id: A0A0A8B694
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1531429:JI75 RS04720
gene id: 1531429:JI75_RS04720
uniprot id: A0A0A8B400
names: Similarity
messages: Belongs to the UPF0045 family.

1531429:JI75 RS04965
gene id: 1531429:JI75_RS04965
uniprot id: A0A0A8B5S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1531429:JI75 RS01325
gene id: 1531429:JI75_RS01325
uniprot id: A0A0A8B3Y2
names: Subcellular Location Annotation
messages: Membrane

1531429:JI75 RS02145
gene id: 1531429:JI75_RS02145
uniprot id: A0A0A8B2N9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1531429:JI75 RS08405
gene id: 1531429:JI75_RS08405
uniprot id: A0A0A8B5D0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1531429:JI75 RS07665
gene id: 1531429:JI75_RS07665
uniprot id: A0A0A8BBT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1531429:JI75 RS01880
gene id: 1531429:JI75_RS01880
uniprot id: A0A0A8B2Q3
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1531429:JI75 RS02945
gene id: 1531429:JI75_RS02945
uniprot id: A0A0A8B9G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Cytoplasm

1531429:JI75 RS01625
gene id: 1531429:JI75_RS01625
uniprot id: A0A0A8B2M6
names: Similarity
messages: Belongs to the peptidase C40 family.

1531429:JI75 RS00920
gene id: 1531429:JI75_RS00920
uniprot id: A0A0A8B236
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1531429:JI75 RS06875
gene id: 1531429:JI75_RS06875
uniprot id: A0A0A8B6J6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

1531429:JI75 RS06385
gene id: 1531429:JI75_RS06385
uniprot id: A0A0A8B4D2
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

1531429:JI75 RS02895
gene id: 1531429:JI75_RS02895
uniprot id: A0A0A8B9F9
names: Subcellular Location Annotation
messages: Membrane

1531429:JI75 RS04880
gene id: 1531429:JI75_RS04880
uniprot id: A0A0A8BAH1
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

1531429:JI75 RS03885
gene id: 1531429:JI75_RS03885
uniprot id: A0A0A8B546
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1531429:JI75 RS01795
gene id: 1531429:JI75_RS01795
uniprot id: A0A0A8B2C5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1531429:JI75 RS00010
gene id: 1531429:JI75_RS00010
uniprot id: A0A0A8B3C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1531429:JI75 RS07880
gene id: 1531429:JI75_RS07880
uniprot id: A0A0A8BBV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1531429:JI75 RS04465
gene id: 1531429:JI75_RS04465
uniprot id: A0A0A8B5I1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1531429:JI75 RS03640
gene id: 1531429:JI75_RS03640
uniprot id: A0A0A8B9S7
names: Subcellular Location Annotation
messages: Membrane

1531429:JI75 RS00345
gene id: 1531429:JI75_RS00345
uniprot id: A0A0A8B3H2
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1531429:JI75 RS01875
gene id: 1531429:JI75_RS01875
uniprot id: A0A0A8B4A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1531429:JI75 RS03305
gene id: 1531429:JI75_RS03305
uniprot id: A0A0A8B4V2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1531429:JI75 RS05665
gene id: 1531429:JI75_RS05665
uniprot id: A0A0A8BAR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1531429:JI75 RS01500
gene id: 1531429:JI75_RS01500
uniprot id: A0A0A8B2G8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1531429:JI75 RS02780
gene id: 1531429:JI75_RS02780
uniprot id: A0A0A8B2Y1
names: Similarity
messages: Belongs to the ArsC family.

1531429:JI75 RS05930
gene id: 1531429:JI75_RS05930
uniprot id: A0A0A8B644
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1531429:JI75 RS08585
gene id: 1531429:JI75_RS08585
uniprot id: A0A0A8B7D3
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1531429:JI75 RS03035
gene id: 1531429:JI75_RS03035
uniprot id: A0A0A8B366
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1531429:JI75 RS07735
gene id: 1531429:JI75_RS07735
uniprot id: A0A0A8B724
names: Similarity
messages: Belongs to the HupF/HypC family.

1531429:JI75 RS06090
gene id: 1531429:JI75_RS06090
uniprot id: A0A0A8B4I1
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1531429:JI75 RS00890
gene id: 1531429:JI75_RS00890
uniprot id: A0A0A8B264
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1531429:JI75 RS04985
gene id: 1531429:JI75_RS04985
uniprot id: A0A0A8BAI5
names: Similarity
messages: Belongs to the glutamine synthetase family.

1531429:JI75 RS06730
gene id: 1531429:JI75_RS06730
uniprot id: A0A0A8B4U0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1531429:JI75 RS08415
gene id: 1531429:JI75_RS08415
uniprot id: A0A0A8B7B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

1531429:JI75 RS06900
gene id: 1531429:JI75_RS06900
uniprot id: A0A0A8B6K2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1531429:JI75 RS03045
gene id: 1531429:JI75_RS03045
uniprot id: A0A0A8B2T7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1531429:JI75 RS07970
gene id: 1531429:JI75_RS07970
uniprot id: A0A0A8B751
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1531429:JI75 RS05720
gene id: 1531429:JI75_RS05720
uniprot id: A0A0A8B419
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1531429:JI75 RS06785
gene id: 1531429:JI75_RS06785
uniprot id: A0A0A8B4V3
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1531429:JI75 RS06435
gene id: 1531429:JI75_RS06435
uniprot id: A0A0A8B4N8
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1531429:JI75 RS03210
gene id: 1531429:JI75_RS03210
uniprot id: A0A0A8B9L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1531429:JI75 RS06790
gene id: 1531429:JI75_RS06790
uniprot id: A0A0A8B4L7
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1531429:JI75 RS06550
gene id: 1531429:JI75_RS06550
uniprot id: A0A0A8B4G7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1531429:JI75 RS07595
gene id: 1531429:JI75_RS07595
uniprot id: A0A0A8B708
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1531429:JI75 RS00055
gene id: 1531429:JI75_RS00055
uniprot id: A0A0A8B3C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1531429:JI75 RS03075
gene id: 1531429:JI75_RS03075
uniprot id: A0A0A8B9J2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1531429:JI75 RS05115
gene id: 1531429:JI75_RS05115
uniprot id: A0A0A8B5U0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1531429:JI75 RS08230
gene id: 1531429:JI75_RS08230
uniprot id: A0A0A8B5A2
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1531429:JI75 RS02270
gene id: 1531429:JI75_RS02270
uniprot id: A0A0A8B2Q5
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1531429:JI75 RS05635
gene id: 1531429:JI75_RS05635
uniprot id: A0A0A8BAQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1531429:JI75 RS03125
gene id: 1531429:JI75_RS03125
uniprot id: A0A0A8B2V5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1531429:JI75 RS05905
gene id: 1531429:JI75_RS05905
uniprot id: A0A0A8B4L4
names: Similarity
messages: Belongs to the glutamine synthetase family.

1531429:JI75 RS04010
gene id: 1531429:JI75_RS04010
uniprot id: A0A0A8B3B1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1531429:JI75 RS06395
gene id: 1531429:JI75_RS06395
uniprot id: A0A0A8B6A9
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1531429:JI75 RS08250
gene id: 1531429:JI75_RS08250
uniprot id: A0A0A8B5I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1531429:JI75 RS06920
gene id: 1531429:JI75_RS06920
uniprot id: A0A0A8BBB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1531429:JI75 RS06170
gene id: 1531429:JI75_RS06170
uniprot id: A0A0A8B4J5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1531429:JI75 RS00570
gene id: 1531429:JI75_RS00570
uniprot id: A0A0A8B1Q8
names: Similarity
messages: Belongs to the creatininase superfamily.

1531429:JI75 RS03040
gene id: 1531429:JI75_RS03040
uniprot id: A0A0A8B328
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1531429:JI75 RS03760
gene id: 1531429:JI75_RS03760
uniprot id: A0A0A8B369
names: Similarity
messages: Belongs to the FBPase class 2 family.

1531429:JI75 RS05235
gene id: 1531429:JI75_RS05235
uniprot id: A0A0A8B4C0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1531429:JI75 RS04130
gene id: 1531429:JI75_RS04130
uniprot id: A0A0A8B598
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1531429:JI75 RS07085
gene id: 1531429:JI75_RS07085
uniprot id: A0A0A8B4S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

1531429:JI75 RS06120
gene id: 1531429:JI75_RS06120
uniprot id: A0A0A8B481
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1531429:JI75 RS02850
gene id: 1531429:JI75_RS02850
uniprot id: A0A0A8B2Z1
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

1531429:JI75 RS06115
gene id: 1531429:JI75_RS06115
uniprot id: A0A0A8B4I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1531429:JI75 RS05925
gene id: 1531429:JI75_RS05925
uniprot id: A0A0A8BAU3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1531429:JI75 RS02990
gene id: 1531429:JI75_RS02990
uniprot id: A0A0A8B318
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1531429:JI75 RS05940
gene id: 1531429:JI75_RS05940
uniprot id: A0A0A8B4L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1531429:JI75 RS04030
gene id: 1531429:JI75_RS04030
uniprot id: A0A0A8B3L0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1531429:JI75 RS00020
gene id: 1531429:JI75_RS00020
uniprot id: A0A0A8B1P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1531429:JI75 RS01070
gene id: 1531429:JI75_RS01070
uniprot id: A0A0A8B1Y0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1531429:JI75 RS06230
gene id: 1531429:JI75_RS06230
uniprot id: A0A0A8B4K5
names: Similarity
messages: Belongs to the peptidase C40 family.

1531429:JI75 RS02590
gene id: 1531429:JI75_RS02590
uniprot id: A0A0A8B2U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1531429:JI75 RS07480
gene id: 1531429:JI75_RS07480
uniprot id: A0A0A8B5F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1531429:JI75 RS08125
gene id: 1531429:JI75_RS08125
uniprot id: A0A0A8B5H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1531429:JI75 RS03225
gene id: 1531429:JI75_RS03225
uniprot id: A0A0A8B364
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

1531429:JI75 RS00470
gene id: 1531429:JI75_RS00470
uniprot id: A0A0A8B1Z8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1531429:JI75 RS03365
gene id: 1531429:JI75_RS03365
uniprot id: A0A0A8B391
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1531429:JI75 RS07385
gene id: 1531429:JI75_RS07385
uniprot id: A0A0A8B4Y6
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1531429:JI75 RS02800
gene id: 1531429:JI75_RS02800
uniprot id: A0A0A8B325
names: Similarity
messages: Belongs to the thioredoxin family.

1531429:JI75 RS01735
gene id: 1531429:JI75_RS01735
uniprot id: A0A0A8B2J2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1531429:JI75 RS08070
gene id: 1531429:JI75_RS08070
uniprot id: A0A0A8B5M6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1531429:JI75 RS01470
gene id: 1531429:JI75_RS01470
uniprot id: A0A0A8B2G4
names: Similarity
messages: Belongs to the asparagine synthetase family.

1531429:JI75 RS07810
gene id: 1531429:JI75_RS07810
uniprot id: A0A0A8B560
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1531429:JI75 RS05890
gene id: 1531429:JI75_RS05890
uniprot id: A0A0A8B441
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1531429:JI75 RS00225
gene id: 1531429:JI75_RS00225
uniprot id: A0A0A8B1V9
names: Subcellular Location Annotation
messages: Membrane

1531429:JI75 RS01185
gene id: 1531429:JI75_RS01185
uniprot id: A0A0A8B2B5
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1531429:JI75 RS06690
gene id: 1531429:JI75_RS06690
uniprot id: A0A0A8BB61
names: Similarity
messages: Belongs to the universal stress protein A family.

1531429:JI75 RS00910
gene id: 1531429:JI75_RS00910
uniprot id: A0A0A8B3Q7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

1531429:JI75 RS02210
gene id: 1531429:JI75_RS02210
uniprot id: A0A0A8B4E7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1531429:JI75 RS03975
gene id: 1531429:JI75_RS03975
uniprot id: A0A0A8B3J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1531429:JI75 RS07010
gene id: 1531429:JI75_RS07010
uniprot id: A0A0A8B559
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1531429:JI75 RS00550
gene id: 1531429:JI75_RS00550
uniprot id: A0A0A8B8G9
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1531429:JI75 RS06930
gene id: 1531429:JI75_RS06930
uniprot id: A0A0A8B541
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1531429:JI75 RS00295
gene id: 1531429:JI75_RS00295
uniprot id: A0A0A8B1X0
names: Subcellular Location Annotation
messages: Membrane

1531429:JI75 RS02760
gene id: 1531429:JI75_RS02760
uniprot id: A0A0A8B2N3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1531429:JI75 RS00435
gene id: 1531429:JI75_RS00435
uniprot id: A0A0A8B1Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1531429:JI75 RS01750
gene id: 1531429:JI75_RS01750
uniprot id: A0A0A8B491
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1531429:JI75 RS02875
gene id: 1531429:JI75_RS02875
uniprot id: A0A0A8B4N4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1531429:JI75 RS00275
gene id: 1531429:JI75_RS00275
uniprot id: A0A0A8B1T2
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1531429:JI75 RS04295
gene id: 1531429:JI75_RS04295
uniprot id: A0A0A8B3U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1531429:JI75 RS01480
gene id: 1531429:JI75_RS01480
uniprot id: A0A0A8B917
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1531429:JI75 RS06345
gene id: 1531429:JI75_RS06345
uniprot id: A0A0A8B698
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1531429:JI75 RS02765
gene id: 1531429:JI75_RS02765
uniprot id: A0A0A8B9E4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1531429:JI75 RS03950
gene id: 1531429:JI75_RS03950
uniprot id: A0A0A8B3A3
names: Function
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.

1531429:JI75 RS01995
gene id: 1531429:JI75_RS01995
uniprot id: A0A0A8B2M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1531429:JI75 RS07825
gene id: 1531429:JI75_RS07825
uniprot id: A0A0A8B736
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1531429:JI75 RS06185
gene id: 1531429:JI75_RS06185
uniprot id: A0A0A8B674
names: Similarity
messages: Belongs to the asparagine synthetase family.

1531429:JI75 RS02660
gene id: 1531429:JI75_RS02660
uniprot id: A0A0A8B4K4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1531429:JI75 RS05885
gene id: 1531429:JI75_RS05885
uniprot id: A0A0A8B4F0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1531429:JI75 RS06160
gene id: 1531429:JI75_RS06160
uniprot id: A0A0A8B672
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1531429:JI75 RS06935
gene id: 1531429:JI75_RS06935
uniprot id: A0A0A8B4Y8
names: Subcellular Location Annotation
messages: Membrane

1531429:JI75 RS03020
gene id: 1531429:JI75_RS03020
uniprot id: A0A0A8B2T1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1531429:JI75 RS07055
gene id: 1531429:JI75_RS07055
uniprot id: A0A0A8B4R7
names: Subcellular Location Annotation
messages: cell wall

1531429:JI75 RS02055
gene id: 1531429:JI75_RS02055
uniprot id: A0A0A8B4C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1531429:JI75 RS07990
gene id: 1531429:JI75_RS07990
uniprot id: A0A0A8BBW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1531429:JI75 RS00725
gene id: 1531429:JI75_RS00725
uniprot id: A0A0A8B1T4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1531429:JI75 RS07225
gene id: 1531429:JI75_RS07225
uniprot id: A0A0A8BBJ4
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1531429:JI75 RS02925
gene id: 1531429:JI75_RS02925
uniprot id: A0A0A8B4P1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1531429:JI75 RS03050
gene id: 1531429:JI75_RS03050
uniprot id: A0A0A8B9I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1531429:JI75 RS08580
gene id: 1531429:JI75_RS08580
uniprot id: A0A0A8BC37
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1531429:JI75 RS05090
gene id: 1531429:JI75_RS05090
uniprot id: A0A0A8B5T6
names: Similarity
messages: Belongs to the ELP3 family.

1531429:JI75 RS00805
gene id: 1531429:JI75_RS00805
uniprot id: A0A0A8B1U4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1531429:JI75 RS02125
gene id: 1531429:JI75_RS02125
uniprot id: A0A0A8B2F8
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1531429:JI75 RS03745
gene id: 1531429:JI75_RS03745
uniprot id: A0A0A8B520
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1531429:JI75 RS03705
gene id: 1531429:JI75_RS03705
uniprot id: A0A0A8B358
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1531429:JI75 RS03080
gene id: 1531429:JI75_RS03080
uniprot id: A0A0A8B4R5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1531429:JI75 RS01670
gene id: 1531429:JI75_RS01670
uniprot id: A0A0A8B480
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1531429:JI75 RS00120
gene id: 1531429:JI75_RS00120
uniprot id: A0A0A8B1H4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1531429:JI75 RS06515
gene id: 1531429:JI75_RS06515
uniprot id: A0A0A8B4V4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1531429:JI75 RS06970
gene id: 1531429:JI75_RS06970
uniprot id: A0A0A8BBD4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1531429:JI75 RS05405
gene id: 1531429:JI75_RS05405
uniprot id: A0A0A8B4E3
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

1531429:JI75 RS01360
gene id: 1531429:JI75_RS01360
uniprot id: A0A0A8B2C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

1531429:JI75 RS07590
gene id: 1531429:JI75_RS07590
uniprot id: A0A0A8BBS6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1531429:JI75 RS03410
gene id: 1531429:JI75_RS03410
uniprot id: A0A0A8B4X5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1531429:JI75 RS01110
gene id: 1531429:JI75_RS01110
uniprot id: A0A0A8B3U0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1531429:JI75 RS03915
gene id: 1531429:JI75_RS03915
uniprot id: A0A0A8B3L8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1531429:JI75 RS00775
gene id: 1531429:JI75_RS00775
uniprot id: A0A0A8B8L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1531429:JI75 RS01665
gene id: 1531429:JI75_RS01665
uniprot id: A0A0A8B935
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1531429:JI75 RS03245
gene id: 1531429:JI75_RS03245
uniprot id: A0A0A8B3A4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1531429:JI75 RS06800
gene id: 1531429:JI75_RS06800
uniprot id: A0A0A8B6H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1531429:JI75 RS02560
gene id: 1531429:JI75_RS02560
uniprot id: A0A0A8B2U5
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1531429:JI75 RS05290
gene id: 1531429:JI75_RS05290
uniprot id: A0A0A8BAL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1531429:JI75 RS04105
gene id: 1531429:JI75_RS04105
uniprot id: A0A0A8B3R4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1531429:JI75 RS03485
gene id: 1531429:JI75_RS03485
uniprot id: A0A0A8B3E5
names: Subcellular Location Annotation
messages: Membrane

1531429:JI75 RS06140
gene id: 1531429:JI75_RS06140
uniprot id: A0A0A8B4P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.