1505907:TEU RS07605
gene id: 1505907:TEU_RS07605
uniprot id: A0A097QUT2
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.

1505907:TEU RS09590
gene id: 1505907:TEU_RS09590
uniprot id: A0A097QVV1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1505907:TEU RS08985
gene id: 1505907:TEU_RS08985
uniprot id: A0A097QVI1
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1505907:TEU RS02065
gene id: 1505907:TEU_RS02065
uniprot id: A0A097QRX3
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS07640
gene id: 1505907:TEU_RS07640
uniprot id: A0A097QUV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm

1505907:TEU RS09290
gene id: 1505907:TEU_RS09290
uniprot id: A0A097QVQ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1505907:TEU RS06095
gene id: 1505907:TEU_RS06095
uniprot id: A0A097QU25
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1505907:TEU RS10225
gene id: 1505907:TEU_RS10225
uniprot id: A0A097QW53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1505907:TEU RS00190
gene id: 1505907:TEU_RS00190
uniprot id: A0A097QQY8
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: In the C-terminal section; belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: In the N-terminal section; belongs to the MobA family.

1505907:TEU RS09850
gene id: 1505907:TEU_RS09850
uniprot id: A0A097QW00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS19 family.
messages: May be involved in maturation of the 30S ribosomal subunit.
messages: Part of the 30S ribosomal subunit.

1505907:TEU RS09580
gene id: 1505907:TEU_RS09580
uniprot id: A0A097QVX7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1505907:TEU RS00270
gene id: 1505907:TEU_RS00270
uniprot id: A0A097QQY2
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS08570
gene id: 1505907:TEU_RS08570
uniprot id: A0A097QVA4
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1505907:TEU RS10600
gene id: 1505907:TEU_RS10600
uniprot id: A0A097QWE7
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS11290
gene id: 1505907:TEU_RS11290
uniprot id: A0A097QWP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1505907:TEU RS09100
gene id: 1505907:TEU_RS09100
uniprot id: A0A097QVK9
names: Similarity
messages: Belongs to the peptidase U62 family.

1505907:TEU RS10815
gene id: 1505907:TEU_RS10815
uniprot id: A0A097QWK7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1505907:TEU RS07720
gene id: 1505907:TEU_RS07720
uniprot id: A0A097QUV6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1505907:TEU RS08090
gene id: 1505907:TEU_RS08090
uniprot id: A0A097QV22
names: Similarity
messages: Belongs to the RuvB family.

1505907:TEU RS03470
gene id: 1505907:TEU_RS03470
uniprot id: A0A097QSQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1505907:TEU RS08710
gene id: 1505907:TEU_RS08710
uniprot id: A0A097QVE9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Homotetramer.

1505907:TEU RS01085
gene id: 1505907:TEU_RS01085
uniprot id: A0A097QRF7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1505907:TEU RS10950
gene id: 1505907:TEU_RS10950
uniprot id: A0A097QWL6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1505907:TEU RS03045
gene id: 1505907:TEU_RS03045
uniprot id: A0A097QSE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecF.

1505907:TEU RS01640
gene id: 1505907:TEU_RS01640
uniprot id: A0A097QRR9
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1505907:TEU RS04920
gene id: 1505907:TEU_RS04920
uniprot id: A0A097QTF5
names: Similarity
messages: Belongs to the GbsR family.

1505907:TEU RS00235
gene id: 1505907:TEU_RS00235
uniprot id: A0A097QQY5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Because the Archaea possessing a type III RuBisCO are all anaerobic, it is most likely that only the carboxylase activity of RuBisCO, and not the competitive oxygenase activity (by which RuBP reacts with O(2) to form one molecule of 3-phosphoglycerate and one molecule of 2-phosphoglycolate), is biologically relevant in these strains.
messages: Belongs to the RuBisCO large chain family. Type III subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3-phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase.
messages: Homodimer or homodecamer. In contrast to form I RuBisCO, the form III RuBisCO is composed solely of large subunits.

1505907:TEU RS06440
gene id: 1505907:TEU_RS06440
uniprot id: A0A097QU50
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds at least 2 Zn(2+) per subunit.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1505907:TEU RS01925
gene id: 1505907:TEU_RS01925
uniprot id: A0A097QRU9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1505907:TEU RS02330
gene id: 1505907:TEU_RS02330
uniprot id: A0A097QS21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

1505907:TEU RS06455
gene id: 1505907:TEU_RS06455
uniprot id: A0A097QU71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Participates in transcription termination.

1505907:TEU RS01340
gene id: 1505907:TEU_RS01340
uniprot id: A0A097QRJ2
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1505907:TEU RS03130
gene id: 1505907:TEU_RS03130
uniprot id: A0A097QSI5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

1505907:TEU RS03435
gene id: 1505907:TEU_RS03435
uniprot id: A0A097QSQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1505907:TEU RS10635
gene id: 1505907:TEU_RS10635
uniprot id: A0A097QWE1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1505907:TEU RS08900
gene id: 1505907:TEU_RS08900
uniprot id: A0A097QVG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1505907:TEU RS03050
gene id: 1505907:TEU_RS03050
uniprot id: A0A097QSG6
names: Function
messages: Part of a potassium transport system.

1505907:TEU RS03480
gene id: 1505907:TEU_RS03480
uniprot id: A0A097QSM8
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

1505907:TEU RS03590
gene id: 1505907:TEU_RS03590
uniprot id: A0A097QSS4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1505907:TEU RS03210
gene id: 1505907:TEU_RS03210
uniprot id: A0A097QSK2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

1505907:TEU RS00870
gene id: 1505907:TEU_RS00870
uniprot id: A0A097QRA5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1505907:TEU RS10050
gene id: 1505907:TEU_RS10050
uniprot id: A0A097QW65
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1505907:TEU RS10435
gene id: 1505907:TEU_RS10435
uniprot id: A0A097QWB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe).

1505907:TEU RS10555
gene id: 1505907:TEU_RS10555
uniprot id: A0A097QWD2
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.

1505907:TEU RS03405
gene id: 1505907:TEU_RS03405
uniprot id: A0A097QSL4
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS03595
gene id: 1505907:TEU_RS03595
uniprot id: A0A097QSP6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1505907:TEU RS02370
gene id: 1505907:TEU_RS02370
uniprot id: A0A097QS39
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1505907:TEU RS08935
gene id: 1505907:TEU_RS08935
uniprot id: A0A097QVH8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1505907:TEU RS06820
gene id: 1505907:TEU_RS06820
uniprot id: A0A097QUD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

1505907:TEU RS01195
gene id: 1505907:TEU_RS01195
uniprot id: A0A097QRG3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

1505907:TEU RS01515
gene id: 1505907:TEU_RS01515
uniprot id: A0A097QRP7
names: Similarity
messages: Belongs to the carbamate kinase family.

1505907:TEU RS01955
gene id: 1505907:TEU_RS01955
uniprot id: A0A097QRV3
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS03150
gene id: 1505907:TEU_RS03150
uniprot id: A0A097QSI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1505907:TEU RS07310
gene id: 1505907:TEU_RS07310
uniprot id: A0A097QUM4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

1505907:TEU RS05215
gene id: 1505907:TEU_RS05215
uniprot id: A0A097QTL1
names: Similarity
messages: Belongs to the enolase family.

1505907:TEU RS00330
gene id: 1505907:TEU_RS00330
uniprot id: A0A097QR12
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS00130
gene id: 1505907:TEU_RS00130
uniprot id: A0A097QQW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

1505907:TEU RS04650
gene id: 1505907:TEU_RS04650
uniprot id: A0A097QT88
names: Subcellular Location Annotation
messages: Nucleus

1505907:TEU RS10205
gene id: 1505907:TEU_RS10205
uniprot id: A0A097QW71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1505907:TEU RS05980
gene id: 1505907:TEU_RS05980
uniprot id: A0A097QTY1
names: Similarity
messages: Belongs to the HypD family.

1505907:TEU RS00380
gene id: 1505907:TEU_RS00380
uniprot id: A0A097QR22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP19 family.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

1505907:TEU RS10675
gene id: 1505907:TEU_RS10675
uniprot id: A0A097QWF0
names: Function
names: Similarity
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
messages: Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO.

1505907:TEU RS10995
gene id: 1505907:TEU_RS10995
uniprot id: A0A097QWK9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1505907:TEU RS01680
gene id: 1505907:TEU_RS01680
uniprot id: A0A097QRQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAC-alpha family.
messages: Contacts the emerging nascent chain on the ribosome.
messages: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.

1505907:TEU RS03060
gene id: 1505907:TEU_RS03060
uniprot id: A0A097QSF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

1505907:TEU RS07205
gene id: 1505907:TEU_RS07205
uniprot id: A0A097QUK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1505907:TEU RS05560
gene id: 1505907:TEU_RS05560
uniprot id: A0A097QTP8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1505907:TEU RS07525
gene id: 1505907:TEU_RS07525
uniprot id: A0A097QUR8
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family.
messages: Part of the 30S ribosomal subunit.

1505907:TEU RS07650
gene id: 1505907:TEU_RS07650
uniprot id: A0A097QUT9
names: Similarity
messages: Belongs to the UPF0235 family.

1505907:TEU RS09935
gene id: 1505907:TEU_RS09935
uniprot id: A0A097QW10
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1505907:TEU RS06755
gene id: 1505907:TEU_RS06755
uniprot id: A0A097QUC8
names: Function
messages: Probably involved in the biogenesis of the ribosome.

1505907:TEU RS05315
gene id: 1505907:TEU_RS05315
uniprot id: A0A097QTM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

1505907:TEU RS03755
gene id: 1505907:TEU_RS03755
uniprot id: A0A097QSR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

1505907:TEU RS03415
gene id: 1505907:TEU_RS03415
uniprot id: A0A097QSK5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1505907:TEU RS00690
gene id: 1505907:TEU_RS00690
uniprot id: A0A097QR63
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1505907:TEU RS02345
gene id: 1505907:TEU_RS02345
uniprot id: A0A097QS34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

1505907:TEU RS05875
gene id: 1505907:TEU_RS05875
uniprot id: A0A097QTV2
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1505907:TEU RS10785
gene id: 1505907:TEU_RS10785
uniprot id: A0A097QWG6
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS10315
gene id: 1505907:TEU_RS10315
uniprot id: A0A097QW92
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1505907:TEU RS02575
gene id: 1505907:TEU_RS02575
uniprot id: A0A097QS68
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS04805
gene id: 1505907:TEU_RS04805
uniprot id: A0A097QTD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1505907:TEU RS09790
gene id: 1505907:TEU_RS09790
uniprot id: A0A097QW16
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS04070
gene id: 1505907:TEU_RS04070
uniprot id: A0A097QSZ7
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

1505907:TEU RS02145
gene id: 1505907:TEU_RS02145
uniprot id: A0A097QRY8
names: Similarity
messages: Belongs to the MoaD family.

1505907:TEU RS04705
gene id: 1505907:TEU_RS04705
uniprot id: A0A097QTB2
names: Similarity
messages: Belongs to the ZPR1 family.

1505907:TEU RS09215
gene id: 1505907:TEU_RS09215
uniprot id: A0A097QVN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1505907:TEU RS09145
gene id: 1505907:TEU_RS09145
uniprot id: A0A097QVL1
names: Similarity
messages: Belongs to the pyruvate kinase family.

1505907:TEU RS02150
gene id: 1505907:TEU_RS02150
uniprot id: A0A097QS03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-archaeol synthase family.
messages: Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
messages: Cell membrane

1505907:TEU RS09185
gene id: 1505907:TEU_RS09185
uniprot id: A0A097QVN2
names: Similarity
messages: Belongs to the NodU/CmcH family.

1505907:TEU RS05210
gene id: 1505907:TEU_RS05210
uniprot id: A0A097QTL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1505907:TEU RS01880
gene id: 1505907:TEU_RS01880
uniprot id: A0A097QRT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

1505907:TEU RS02300
gene id: 1505907:TEU_RS02300
uniprot id: A0A097QS26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DNA polymerase II family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

1505907:TEU RS03430
gene id: 1505907:TEU_RS03430
uniprot id: A0A097QSL9
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

1505907:TEU RS08675
gene id: 1505907:TEU_RS08675
uniprot id: A0A097QVD5
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS07655
gene id: 1505907:TEU_RS07655
uniprot id: A0A097QUU3
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS03070
gene id: 1505907:TEU_RS03070
uniprot id: A0A097QSE7
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1505907:TEU RS05700
gene id: 1505907:TEU_RS05700
uniprot id: A0A097QTT7
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

1505907:TEU RS04980
gene id: 1505907:TEU_RS04980
uniprot id: A0A097QTE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1505907:TEU RS08355
gene id: 1505907:TEU_RS08355
uniprot id: A0A097QV66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1505907:TEU RS09070
gene id: 1505907:TEU_RS09070
uniprot id: A0A097QVK5
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS06660
gene id: 1505907:TEU_RS06660
uniprot id: A0A097QU88
names: Similarity
messages: Belongs to the arginase family.

1505907:TEU RS00360
gene id: 1505907:TEU_RS00360
uniprot id: A0A097QR01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1505907:TEU RS08590
gene id: 1505907:TEU_RS08590
uniprot id: A0A097QVC4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1505907:TEU RS04350
gene id: 1505907:TEU_RS04350
uniprot id: A0A097QT36
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

1505907:TEU RS08805
gene id: 1505907:TEU_RS08805
uniprot id: A0A097QVF5
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1505907:TEU RS11240
gene id: 1505907:TEU_RS11240
uniprot id: A0A097QWP5
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1505907:TEU RS08755
gene id: 1505907:TEU_RS08755
uniprot id: A0A097QVF2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

1505907:TEU RS07725
gene id: 1505907:TEU_RS07725
uniprot id: A0A097QUV4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily.
messages: Has ATPase and non-specific DNA-binding activities.

1505907:TEU RS01025
gene id: 1505907:TEU_RS01025
uniprot id: A0A097QRC3
names: Function
names: Similarity
messages: Belongs to the FAU-1 family.
messages: Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences.

1505907:TEU RS01700
gene id: 1505907:TEU_RS01700
uniprot id: A0A097QRQ6
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1505907:TEU RS02495
gene id: 1505907:TEU_RS02495
uniprot id: A0A097QS51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1505907:TEU RS05105
gene id: 1505907:TEU_RS05105
uniprot id: A0A097QTH2
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS02860
gene id: 1505907:TEU_RS02860
uniprot id: A0A097QSC7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1505907:TEU RS07540
gene id: 1505907:TEU_RS07540
uniprot id: A0A097QUR9
names: Similarity
messages: Belongs to the UPF0212 family.

1505907:TEU RS06775
gene id: 1505907:TEU_RS06775
uniprot id: A0A097QWV0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1505907:TEU RS02890
gene id: 1505907:TEU_RS02890
uniprot id: A0A097QSB4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1505907:TEU RS10330
gene id: 1505907:TEU_RS10330
uniprot id: A0A097QW95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Membrane

1505907:TEU RS04940
gene id: 1505907:TEU_RS04940
uniprot id: A0A097QTF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1505907:TEU RS06825
gene id: 1505907:TEU_RS06825
uniprot id: A0A097QUC1
names: Similarity
messages: Belongs to the UPF0440 family.

1505907:TEU RS00420
gene id: 1505907:TEU_RS00420
uniprot id: A0A097QR18
names: Subcellular Location Annotation
messages: Cell membrane

1505907:TEU RS02650
gene id: 1505907:TEU_RS02650
uniprot id: A0A097QS86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

1505907:TEU RS10400
gene id: 1505907:TEU_RS10400
uniprot id: A0A097QW88
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the UPF0165 family.

1505907:TEU RS10690
gene id: 1505907:TEU_RS10690
uniprot id: A0A097QWG2
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

1505907:TEU RS07115
gene id: 1505907:TEU_RS07115
uniprot id: A0A097QUI6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the asparaginase 1 family. GatD subfamily.
messages: Heterodimer of GatD and GatE.

1505907:TEU RS09250
gene id: 1505907:TEU_RS09250
uniprot id: A0A097QVN9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1505907:TEU RS08285
gene id: 1505907:TEU_RS08285
uniprot id: A0A097QV58
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS00725
gene id: 1505907:TEU_RS00725
uniprot id: A0A097QR70
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1505907:TEU RS07305
gene id: 1505907:TEU_RS07305
uniprot id: A0A097QUQ1
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS05015
gene id: 1505907:TEU_RS05015
uniprot id: A0A097QTG4
names: Similarity
messages: Belongs to the SUI1 family.

1505907:TEU RS00335
gene id: 1505907:TEU_RS00335
uniprot id: A0A097QQZ6
names: Similarity
messages: Belongs to the UPF0200 family.

1505907:TEU RS05085
gene id: 1505907:TEU_RS05085
uniprot id: A0A097QTG2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1505907:TEU RS03185
gene id: 1505907:TEU_RS03185
uniprot id: A0A097QSH8
names: Similarity
messages: Belongs to the UPF0216 family.

1505907:TEU RS04515
gene id: 1505907:TEU_RS04515
uniprot id: A0A097QT70
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

1505907:TEU RS00220
gene id: 1505907:TEU_RS00220
uniprot id: A0A097QQX5
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

1505907:TEU RS08920
gene id: 1505907:TEU_RS08920
uniprot id: A0A097QVI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
messages: Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.

1505907:TEU RS05620
gene id: 1505907:TEU_RS05620
uniprot id: A0A097QTT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SPT5 family.
messages: Belongs to the archaeal Spt5 family.
messages: Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).
messages: Stimulates transcription elongation.

1505907:TEU RS04665
gene id: 1505907:TEU_RS04665
uniprot id: A0A097QT90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-beta/eIF-5 family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

1505907:TEU RS05975
gene id: 1505907:TEU_RS05975
uniprot id: A0A097QTX4
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

1505907:TEU RS00135
gene id: 1505907:TEU_RS00135
uniprot id: A0A097QQV8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1505907:TEU RS07830
gene id: 1505907:TEU_RS07830
uniprot id: A0A097QUX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1505907:TEU RS00090
gene id: 1505907:TEU_RS00090
uniprot id: A0A097QQU9
names: Subunit
messages: Homodimer.

1505907:TEU RS07745
gene id: 1505907:TEU_RS07745
uniprot id: A0A097QUX8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-64 and Arg-67) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription.

1505907:TEU RS05220
gene id: 1505907:TEU_RS05220
uniprot id: A0A097QTI8
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1505907:TEU RS06810
gene id: 1505907:TEU_RS06810
uniprot id: A0A097QUD3
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

1505907:TEU RS00340
gene id: 1505907:TEU_RS00340
uniprot id: A0A097QR15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. Hel308 subfamily.
messages: DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
messages: Monomer.

1505907:TEU RS02940
gene id: 1505907:TEU_RS02940
uniprot id: A0A097QSC4
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS05005
gene id: 1505907:TEU_RS05005
uniprot id: A0A097QTF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head.
messages: Part of the 30S ribosomal subunit.

1505907:TEU RS06790
gene id: 1505907:TEU_RS06790
uniprot id: A0A097QUC4
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS08050
gene id: 1505907:TEU_RS08050
uniprot id: A0A097QV14
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1505907:TEU RS06310
gene id: 1505907:TEU_RS06310
uniprot id: A0A097QU26
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1505907:TEU RS05960
gene id: 1505907:TEU_RS05960
uniprot id: A0A097QTX5
names: Similarity
messages: Belongs to the HypE family.

1505907:TEU RS04215
gene id: 1505907:TEU_RS04215
uniprot id: A0A097QT18
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1505907:TEU RS10275
gene id: 1505907:TEU_RS10275
uniprot id: A0A097QW63
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
messages: Homodimer.

1505907:TEU RS07710
gene id: 1505907:TEU_RS07710
uniprot id: A0A097QUV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Forms a Heterooligomeric complex of two stacked eight-membered rings.
messages: Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity.

1505907:TEU RS08885
gene id: 1505907:TEU_RS08885
uniprot id: A0A097QVH0
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.

1505907:TEU RS08055
gene id: 1505907:TEU_RS08055
uniprot id: A0A097QV30
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS06990
gene id: 1505907:TEU_RS06990
uniprot id: A0A097QUG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

1505907:TEU RS05615
gene id: 1505907:TEU_RS05615
uniprot id: A0A097QTS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY (alpha), SecG (beta) and SecE (gamma) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Membrane

1505907:TEU RS07845
gene id: 1505907:TEU_RS07845
uniprot id: A0A097QUX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1505907:TEU RS02510
gene id: 1505907:TEU_RS02510
uniprot id: A0A097QS69
names: Similarity
messages: Belongs to the PstS family.

1505907:TEU RS01430
gene id: 1505907:TEU_RS01430
uniprot id: A0A097QRN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1505907:TEU RS09585
gene id: 1505907:TEU_RS09585
uniprot id: A0A097QVU9
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS09115
gene id: 1505907:TEU_RS09115
uniprot id: A0A097QVL8
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1505907:TEU RS01470
gene id: 1505907:TEU_RS01470
uniprot id: A0A097QRL2
names: Similarity
messages: Belongs to the UPF0147 family.

1505907:TEU RS09400
gene id: 1505907:TEU_RS09400
uniprot id: A0A097QVR5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Part of the 30S ribosomal subunit.

1505907:TEU RS09255
gene id: 1505907:TEU_RS09255
uniprot id: A0A097QVP0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

1505907:TEU RS07535
gene id: 1505907:TEU_RS07535
uniprot id: A0A097QUU1
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1505907:TEU RS05460
gene id: 1505907:TEU_RS05460
uniprot id: A0A097QTP9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeal MetE family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. The physiological methyl donor is unknown.

1505907:TEU RS00440
gene id: 1505907:TEU_RS00440
uniprot id: A0A097QR34
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1505907:TEU RS09180
gene id: 1505907:TEU_RS09180
uniprot id: A0A097QVM5
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1505907:TEU RS00245
gene id: 1505907:TEU_RS00245
uniprot id: A0A097QQZ7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

1505907:TEU RS05090
gene id: 1505907:TEU_RS05090
uniprot id: A0A097QTI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1505907:TEU RS09140
gene id: 1505907:TEU_RS09140
uniprot id: A0A097QVM3
names: Function
names: Similarity
messages: Belongs to the adenylate cyclase family. DacZ subfamily.
messages: Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.

1505907:TEU RS06905
gene id: 1505907:TEU_RS06905
uniprot id: A0A097QUE8
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1505907:TEU RS00695
gene id: 1505907:TEU_RS00695
uniprot id: A0A097QR79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1505907:TEU RS04725
gene id: 1505907:TEU_RS04725
uniprot id: A0A097QTB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp41 subfamily.
messages: Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm

1505907:TEU RS03135
gene id: 1505907:TEU_RS03135
uniprot id: A0A097QSH0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1505907:TEU RS08760
gene id: 1505907:TEU_RS08760
uniprot id: A0A097QVE1
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

1505907:TEU RS00900
gene id: 1505907:TEU_RS00900
uniprot id: A0A097QRA3
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1505907:TEU RS09285
gene id: 1505907:TEU_RS09285
uniprot id: A0A097QVQ3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the THI4 family.
messages: Homooctamer; tetramer of dimers.
messages: Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1505907:TEU RS00590
gene id: 1505907:TEU_RS00590
uniprot id: A0A097QR59
names: Similarity
messages: Belongs to the NOP5/NOP56 family.

1505907:TEU RS05400
gene id: 1505907:TEU_RS05400
uniprot id: A0A097QTN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1505907:TEU RS07885
gene id: 1505907:TEU_RS07885
uniprot id: A0A097QUY0
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

1505907:TEU RS00780
gene id: 1505907:TEU_RS00780
uniprot id: A0A097QR99
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1505907:TEU RS02025
gene id: 1505907:TEU_RS02025
uniprot id: A0A097QRX2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1505907:TEU RS02930
gene id: 1505907:TEU_RS02930
uniprot id: A0A097QSD2
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS09030
gene id: 1505907:TEU_RS09030
uniprot id: A0A097QVK2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1505907:TEU RS03925
gene id: 1505907:TEU_RS03925
uniprot id: A0A097QSX3
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS31 family.
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 30S ribosomal subunit.

1505907:TEU RS05110
gene id: 1505907:TEU_RS05110
uniprot id: A0A097QTG7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

1505907:TEU RS08700
gene id: 1505907:TEU_RS08700
uniprot id: A0A097QVE0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
messages: Monomer.
messages: The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity.

1505907:TEU RS04050
gene id: 1505907:TEU_RS04050
uniprot id: A0A097QSY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1505907:TEU RS00790
gene id: 1505907:TEU_RS00790
uniprot id: A0A097QR87
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS05690
gene id: 1505907:TEU_RS05690
uniprot id: A0A097QTR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm

1505907:TEU RS06020
gene id: 1505907:TEU_RS06020
uniprot id: A0A097QTY2
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS08520
gene id: 1505907:TEU_RS08520
uniprot id: A0A097QV95
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1505907:TEU RS09890
gene id: 1505907:TEU_RS09890
uniprot id: A0A097QW37
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1505907:TEU RS03825
gene id: 1505907:TEU_RS03825
uniprot id: A0A097QSS1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1505907:TEU RS10320
gene id: 1505907:TEU_RS10320
uniprot id: A0A097QWB4
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

1505907:TEU RS10460
gene id: 1505907:TEU_RS10460
uniprot id: A0A097QWC0
names: Function
names: Similarity
messages: Belongs to the 2-phosphoglycerate kinase family.
messages: Catalyzes the phosphorylation of 2-phosphoglycerate to 2,3-diphosphoglycerate. Involved in the biosynthesis of cyclic 2,3-bisphosphoglycerate, a thermoprotectant.

1505907:TEU RS00910
gene id: 1505907:TEU_RS00910
uniprot id: A0A097QRA6
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1505907:TEU RS01960
gene id: 1505907:TEU_RS01960
uniprot id: A0A097QRU6
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS01255
gene id: 1505907:TEU_RS01255
uniprot id: A0A097QRH3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1505907:TEU RS00705
gene id: 1505907:TEU_RS00705
uniprot id: A0A097QR86
names: Similarity
messages: Belongs to the GARS family.

1505907:TEU RS05230
gene id: 1505907:TEU_RS05230
uniprot id: A0A097QTI6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL40 family.

1505907:TEU RS07185
gene id: 1505907:TEU_RS07185
uniprot id: A0A097QUJ9
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the archaeal N-glycosylase/DNA lyase (AGOG) family.
messages: Contains two alpha-helical subdomains, with the 8-oxoguanine binding site located in a cleft at their interface. Contains a helix-hairpin-helix (HhH) structural motif and a Gly/Pro-rich sequence followed by a conserved Asp (HhH-GPD motif).
messages: DNA repair enzyme that is part of the base excision repair (BER) pathway; protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine (GO), from single- and double-stranded DNA substrates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1505907:TEU RS02205
gene id: 1505907:TEU_RS02205
uniprot id: A0A097QS13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1505907:TEU RS00175
gene id: 1505907:TEU_RS00175
uniprot id: A0A097QQY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1505907:TEU RS04985
gene id: 1505907:TEU_RS04985
uniprot id: A0A097QTE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29.

1505907:TEU RS00645
gene id: 1505907:TEU_RS00645
uniprot id: A0A097QR54
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

1505907:TEU RS09450
gene id: 1505907:TEU_RS09450
uniprot id: A0A097QVT1
names: Similarity
messages: Belongs to the RutC family.

1505907:TEU RS09390
gene id: 1505907:TEU_RS09390
uniprot id: A0A097QVS3
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS08470
gene id: 1505907:TEU_RS08470
uniprot id: A0A097QV84
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1505907:TEU RS01250
gene id: 1505907:TEU_RS01250
uniprot id: A0A097QRI4
names: Similarity
messages: Belongs to the BtpA family.

1505907:TEU RS01860
gene id: 1505907:TEU_RS01860
uniprot id: A0A097QRT0
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS02505
gene id: 1505907:TEU_RS02505
uniprot id: A0A097QS61
names: Similarity
messages: Belongs to the alkaline phosphatase family.

1505907:TEU RS02385
gene id: 1505907:TEU_RS02385
uniprot id: A0A097QS29
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1505907:TEU RS05515
gene id: 1505907:TEU_RS05515
uniprot id: A0A097QTR1
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Probably part of the ribosome quality control system (RQC). May mediate the addition of alanine residues (Ala tailing) to incompletely synthesized nascent chains from stalled ribosomes, leading to their degradation.

1505907:TEU RS04735
gene id: 1505907:TEU_RS04735
uniprot id: A0A097QTA4
names: Similarity
messages: Belongs to the SDO1/SBDS family.

1505907:TEU RS05060
gene id: 1505907:TEU_RS05060
uniprot id: A0A097QTF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1505907:TEU RS06970
gene id: 1505907:TEU_RS06970
uniprot id: A0A097QUI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.
messages: Homodimer.
messages: Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.

1505907:TEU RS08020
gene id: 1505907:TEU_RS08020
uniprot id: A0A097QV08
names: Similarity
messages: Belongs to the AAA ATPase family.

1505907:TEU RS09460
gene id: 1505907:TEU_RS09460
uniprot id: A0A097QVS6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S16 family. Archaeal LonB subfamily.
messages: Cell membrane
messages: Homohexamer. Organized in a ring with a central cavity.
messages: Membrane

1505907:TEU RS02435
gene id: 1505907:TEU_RS02435
uniprot id: A0A097QS40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm

1505907:TEU RS09625
gene id: 1505907:TEU_RS09625
uniprot id: A0A097QVV8
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS10760
gene id: 1505907:TEU_RS10760
uniprot id: A0A097QWG0
names: Similarity
messages: Belongs to the UPF0179 family.

1505907:TEU RS03040
gene id: 1505907:TEU_RS03040
uniprot id: A0A097QSH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecD.

1505907:TEU RS04230
gene id: 1505907:TEU_RS04230
uniprot id: A0A097QT15
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

1505907:TEU RS03490
gene id: 1505907:TEU_RS03490
uniprot id: A0A097QSM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

1505907:TEU RS01720
gene id: 1505907:TEU_RS01720
uniprot id: A0A097QRQ9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1505907:TEU RS06945
gene id: 1505907:TEU_RS06945
uniprot id: A0A097QUI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1505907:TEU RS00890
gene id: 1505907:TEU_RS00890
uniprot id: A0A097QRC1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1505907:TEU RS01380
gene id: 1505907:TEU_RS01380
uniprot id: A0A097QRM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1505907:TEU RS02320
gene id: 1505907:TEU_RS02320
uniprot id: A0A097QS30
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS03645
gene id: 1505907:TEU_RS03645
uniprot id: A0A097QSQ5
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1505907:TEU RS01105
gene id: 1505907:TEU_RS01105
uniprot id: A0A097QRE0
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MRE11/RAD32 family.
messages: Binds 2 manganese ions per subunit.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nuclease activity is regulated by Rad50.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity.

1505907:TEU RS10860
gene id: 1505907:TEU_RS10860
uniprot id: A0A097QWI1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1505907:TEU RS03425
gene id: 1505907:TEU_RS03425
uniprot id: A0A097QSP4
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS05605
gene id: 1505907:TEU_RS05605
uniprot id: A0A097QTQ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DtdA deacylase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
messages: Monomer.

1505907:TEU RS05355
gene id: 1505907:TEU_RS05355
uniprot id: A0A097QTN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Cytoplasm
messages: Homodimer.

1505907:TEU RS02055
gene id: 1505907:TEU_RS02055
uniprot id: A0A097QRX4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1505907:TEU RS03085
gene id: 1505907:TEU_RS03085
uniprot id: A0A097QSG0
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit.

1505907:TEU RS01070
gene id: 1505907:TEU_RS01070
uniprot id: A0A097QRD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcL subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

1505907:TEU RS00830
gene id: 1505907:TEU_RS00830
uniprot id: A0A097QRA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Forms a Heterooligomeric complex of two stacked eight-membered rings.
messages: Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity.

1505907:TEU RS08295
gene id: 1505907:TEU_RS08295
uniprot id: A0A097QV65
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1505907:TEU RS01715
gene id: 1505907:TEU_RS01715
uniprot id: A0A097QRT1
names: Similarity
messages: Belongs to the UPF0111 family.

1505907:TEU RS09865
gene id: 1505907:TEU_RS09865
uniprot id: A0A097QW31
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

1505907:TEU RS08080
gene id: 1505907:TEU_RS08080
uniprot id: A0A097QV35
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1505907:TEU RS05805
gene id: 1505907:TEU_RS05805
uniprot id: A0A097QTV0
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1505907:TEU RS07715
gene id: 1505907:TEU_RS07715
uniprot id: A0A097QUX3
names: Similarity
messages: Belongs to the protein kinase superfamily. BUD32 family.

1505907:TEU RS07790
gene id: 1505907:TEU_RS07790
uniprot id: A0A097QUW4
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.
messages: Belongs to the radical SAM superfamily. NifB family.

1505907:TEU RS06360
gene id: 1505907:TEU_RS06360
uniprot id: A0A097QU72
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

1505907:TEU RS03625
gene id: 1505907:TEU_RS03625
uniprot id: A0A097QSU3
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

1505907:TEU RS06625
gene id: 1505907:TEU_RS06625
uniprot id: A0A097QU83
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

1505907:TEU RS05305
gene id: 1505907:TEU_RS05305
uniprot id: A0A097QTK3
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.

1505907:TEU RS05240
gene id: 1505907:TEU_RS05240
uniprot id: A0A097QTL4
names: Similarity
messages: Belongs to the FUN14 family.

1505907:TEU RS06675
gene id: 1505907:TEU_RS06675
uniprot id: A0A097QUA6
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Catalyzes the dephosphorylation of D,L-glyceraldehyde 3-phosphate in vitro.

1505907:TEU RS04125
gene id: 1505907:TEU_RS04125
uniprot id: A0A097QT05
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1505907:TEU RS02310
gene id: 1505907:TEU_RS02310
uniprot id: A0A097QS12
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

1505907:TEU RS00880
gene id: 1505907:TEU_RS00880
uniprot id: A0A097QRB3
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1505907:TEU RS05480
gene id: 1505907:TEU_RS05480
uniprot id: A0A097QTN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1505907:TEU RS01550
gene id: 1505907:TEU_RS01550
uniprot id: A0A097QRM4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FBP aldolase/phosphatase family.
messages: Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
messages: Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.
messages: Homooctamer; dimer of tetramers.

1505907:TEU RS00630
gene id: 1505907:TEU_RS00630
uniprot id: A0A097QR61
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

1505907:TEU RS06170
gene id: 1505907:TEU_RS06170
uniprot id: A0A097QU18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.
messages: Membrane

1505907:TEU RS03145
gene id: 1505907:TEU_RS03145
uniprot id: A0A097QSF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1505907:TEU RS05470
gene id: 1505907:TEU_RS05470
uniprot id: A0A097QTQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1505907:TEU RS05075
gene id: 1505907:TEU_RS05075
uniprot id: A0A097QTI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1505907:TEU RS05525
gene id: 1505907:TEU_RS05525
uniprot id: A0A097QTS0
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

1505907:TEU RS05065
gene id: 1505907:TEU_RS05065
uniprot id: A0A097QTH3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

1505907:TEU RS01740
gene id: 1505907:TEU_RS01740
uniprot id: A0A097QRR0
names: Similarity
messages: Belongs to the malic enzymes family.

1505907:TEU RS00720
gene id: 1505907:TEU_RS00720
uniprot id: A0A097QR85
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1505907:TEU RS07155
gene id: 1505907:TEU_RS07155
uniprot id: A0A097QUJ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1505907:TEU RS10215
gene id: 1505907:TEU_RS10215
uniprot id: A0A097QW72
names: Similarity
messages: Belongs to the UPF0252 family.

1505907:TEU RS01405
gene id: 1505907:TEU_RS01405
uniprot id: A0A097QRN1
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS09535
gene id: 1505907:TEU_RS09535
uniprot id: A0A097QVU2
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS04100
gene id: 1505907:TEU_RS04100
uniprot id: A0A097QT00
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1505907:TEU RS09320
gene id: 1505907:TEU_RS09320
uniprot id: A0A097QVQ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1505907:TEU RS00165
gene id: 1505907:TEU_RS00165
uniprot id: A0A097QQY3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal FAD synthase family.
messages: Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1505907:TEU RS04205
gene id: 1505907:TEU_RS04205
uniprot id: A0A097QT11
names: Function
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of both single-stranded RNA (ssRNA) and single-stranded DNA (ssDNA). Exhibits a strong preference for ssRNA.

1505907:TEU RS06465
gene id: 1505907:TEU_RS06465
uniprot id: A0A097QU54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.
messages: Part of the 30S ribosomal subunit.

1505907:TEU RS04200
gene id: 1505907:TEU_RS04200
uniprot id: A0A097QT14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. DGGGP synthase subfamily.
messages: Cell membrane
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

1505907:TEU RS02490
gene id: 1505907:TEU_RS02490
uniprot id: A0A097QS45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1505907:TEU RS10155
gene id: 1505907:TEU_RS10155
uniprot id: A0A097QW45
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1505907:TEU RS04720
gene id: 1505907:TEU_RS04720
uniprot id: A0A097QTA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp42 subfamily.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.

1505907:TEU RS05670
gene id: 1505907:TEU_RS05670
uniprot id: A0A097QTT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DnaG primase family.
messages: Forms a ternary complex with MCM helicase and DNA. Component of the archaeal exosome complex.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.

1505907:TEU RS08375
gene id: 1505907:TEU_RS08375
uniprot id: A0A097QV87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm
messages: Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
messages: Heterodimer of two subunits, one of which binds GTP.

1505907:TEU RS00855
gene id: 1505907:TEU_RS00855
uniprot id: A0A097QR95
names: Function
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.

1505907:TEU RS06365
gene id: 1505907:TEU_RS06365
uniprot id: A0A097QU36
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1505907:TEU RS00655
gene id: 1505907:TEU_RS00655
uniprot id: A0A097QR67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1505907:TEU RS01625
gene id: 1505907:TEU_RS01625
uniprot id: A0A097QRP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1505907:TEU RS01015
gene id: 1505907:TEU_RS01015
uniprot id: A0A097QRC6
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family. RadB subfamily.
messages: Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange.

1505907:TEU RS05610
gene id: 1505907:TEU_RS05610
uniprot id: A0A097QTS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1505907:TEU RS03095
gene id: 1505907:TEU_RS03095
uniprot id: A0A097QSF1
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1505907:TEU RS11000
gene id: 1505907:TEU_RS11000
uniprot id: A0A097QWM7
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

1505907:TEU RS10800
gene id: 1505907:TEU_RS10800
uniprot id: A0A097QWG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Nucleus

1505907:TEU RS10480
gene id: 1505907:TEU_RS10480
uniprot id: A0A097QWA4
names: Similarity
messages: Belongs to the HsdR family.

1505907:TEU RS09830
gene id: 1505907:TEU_RS09830
uniprot id: A0A097QVZ3
names: Function
names: Similarity
messages: Belongs to the eIF-6 family.
messages: Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.

1505907:TEU RS02960
gene id: 1505907:TEU_RS02960
uniprot id: A0A097QSG1
names: Cofactor
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1505907:TEU RS01075
gene id: 1505907:TEU_RS01075
uniprot id: A0A097QRF1
names: Similarity
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.

1505907:TEU RS09000
gene id: 1505907:TEU_RS09000
uniprot id: A0A097QVJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1505907:TEU RS07695
gene id: 1505907:TEU_RS07695
uniprot id: A0A097QUV1
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1505907:TEU RS07150
gene id: 1505907:TEU_RS07150
uniprot id: A0A097QUM2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1505907:TEU RS03420
gene id: 1505907:TEU_RS03420
uniprot id: A0A097QSP2
names: Similarity
messages: Belongs to the UPF0146 family.

1505907:TEU RS00230
gene id: 1505907:TEU_RS00230
uniprot id: A0A097QQZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

1505907:TEU RS02975
gene id: 1505907:TEU_RS02975
uniprot id: A0A097QSE9
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS10970
gene id: 1505907:TEU_RS10970
uniprot id: A0A097QWK4
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS09820
gene id: 1505907:TEU_RS09820
uniprot id: A0A097QVY3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

1505907:TEU RS03830
gene id: 1505907:TEU_RS03830
uniprot id: A0A097QSW5
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS11225
gene id: 1505907:TEU_RS11225
uniprot id: A0A097QWP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

1505907:TEU RS04490
gene id: 1505907:TEU_RS04490
uniprot id: A0A097QT80
names: Similarity
messages: Belongs to the peptidase S8 family.

1505907:TEU RS06530
gene id: 1505907:TEU_RS06530
uniprot id: A0A097QU69
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1505907:TEU RS06430
gene id: 1505907:TEU_RS06430
uniprot id: A0A097QU67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1505907:TEU RS05740
gene id: 1505907:TEU_RS05740
uniprot id: A0A097QTU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1505907:TEU RS00650
gene id: 1505907:TEU_RS00650
uniprot id: A0A097QR74
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates.

1505907:TEU RS09160
gene id: 1505907:TEU_RS09160
uniprot id: A0A097QVM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1505907:TEU RS01950
gene id: 1505907:TEU_RS01950
uniprot id: A0A097QRV6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1505907:TEU RS03180
gene id: 1505907:TEU_RS03180
uniprot id: A0A097QSJ5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1505907:TEU RS00635
gene id: 1505907:TEU_RS00635
uniprot id: A0A097QR57
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1505907:TEU RS01635
gene id: 1505907:TEU_RS01635
uniprot id: A0A097QRN7
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1505907:TEU RS07285
gene id: 1505907:TEU_RS07285
uniprot id: A0A097QUL8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M54 family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic, whereas the other seems to have a structural role.
messages: Monomer.
messages: Probable zinc metalloprotease whose natural substrate is unknown.

1505907:TEU RS01130
gene id: 1505907:TEU_RS01130
uniprot id: A0A097QRE4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1505907:TEU RS03900
gene id: 1505907:TEU_RS03900
uniprot id: A0A097QSX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1505907:TEU RS03915
gene id: 1505907:TEU_RS03915
uniprot id: A0A097QSY0
names: Function
names: Similarity
messages: Belongs to the GTP-dependent DPCK family.
messages: Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).

1505907:TEU RS00500
gene id: 1505907:TEU_RS00500
uniprot id: A0A097QR43
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

1505907:TEU RS05990
gene id: 1505907:TEU_RS05990
uniprot id: A0A097QU04
names: Similarity
messages: Belongs to the HupF/HypC family.

1505907:TEU RS02110
gene id: 1505907:TEU_RS02110
uniprot id: A0A097QRY2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1505907:TEU RS04645
gene id: 1505907:TEU_RS04645
uniprot id: A0A097QTA0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1505907:TEU RS06950
gene id: 1505907:TEU_RS06950
uniprot id: A0A097QUF8
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1505907:TEU RS08310
gene id: 1505907:TEU_RS08310
uniprot id: A0A097QV64
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1505907:TEU RS08270
gene id: 1505907:TEU_RS08270
uniprot id: A0A097QV60
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS08720
gene id: 1505907:TEU_RS08720
uniprot id: A0A097QVD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
messages: Belongs to the TiaS family.
messages: Cytoplasm

1505907:TEU RS06410
gene id: 1505907:TEU_RS06410
uniprot id: A0A097QU82
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily.
messages: Binds 1 FAD per subunit.
messages: Is involved in the reduction of 2,3-digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains.
messages: Reduction reaction proceeds via syn addition of hydrogen for double bonds.

1505907:TEU RS02325
gene id: 1505907:TEU_RS02325
uniprot id: A0A097QS32
names: Caution
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family.
messages: Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1505907:TEU RS08615
gene id: 1505907:TEU_RS08615
uniprot id: A0A097QVC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1505907:TEU RS05080
gene id: 1505907:TEU_RS05080
uniprot id: A0A097QTG6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Part of the 30S ribosomal subunit. Contacts protein S4.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1505907:TEU RS04600
gene id: 1505907:TEU_RS04600
uniprot id: A0A097QT78
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1505907:TEU RS02765
gene id: 1505907:TEU_RS02765
uniprot id: A0A097QSC3
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

1505907:TEU RS07135
gene id: 1505907:TEU_RS07135
uniprot id: A0A097QUI7
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1505907:TEU RS00505
gene id: 1505907:TEU_RS00505
uniprot id: A0A097QR35
names: Function
names: Subunit
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

1505907:TEU RS05880
gene id: 1505907:TEU_RS05880
uniprot id: A0A097QTW3
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS01120
gene id: 1505907:TEU_RS01120
uniprot id: A0A097QRE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1505907:TEU RS07600
gene id: 1505907:TEU_RS07600
uniprot id: A0A097QUS8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

1505907:TEU RS07610
gene id: 1505907:TEU_RS07610
uniprot id: A0A097QUT1
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS05540
gene id: 1505907:TEU_RS05540
uniprot id: A0A097QTR4
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS10045
gene id: 1505907:TEU_RS10045
uniprot id: A0A097QW39
names: Function
names: Similarity
messages: Belongs to the THEP1 NTPase family.
messages: Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency.

1505907:TEU RS09315
gene id: 1505907:TEU_RS09315
uniprot id: A0A097QVQ8
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1505907:TEU RS10820
gene id: 1505907:TEU_RS10820
uniprot id: A0A097QWH1
names: Similarity
messages: Belongs to the SfsA family.

1505907:TEU RS04945
gene id: 1505907:TEU_RS04945
uniprot id: A0A097QTG0
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS09305
gene id: 1505907:TEU_RS09305
uniprot id: A0A097QVQ0
names: Function
names: Similarity
messages: Belongs to the archaeal IMP cyclohydrolase family.
messages: Catalyzes the cyclization of 5-formylamidoimidazole-4-carboxamide ribonucleotide to IMP.

1505907:TEU RS04885
gene id: 1505907:TEU_RS04885
uniprot id: A0A097QTF0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1505907:TEU RS03640
gene id: 1505907:TEU_RS03640
uniprot id: A0A097QST4
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
messages: Homodimer.

1505907:TEU RS06975
gene id: 1505907:TEU_RS06975
uniprot id: A0A097QUG2
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS05345
gene id: 1505907:TEU_RS05345
uniprot id: A0A097QTK4
names: Similarity
messages: Belongs to the MEMO1 family.

1505907:TEU RS00185
gene id: 1505907:TEU_RS00185
uniprot id: A0A097QQW8
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1505907:TEU RS02870
gene id: 1505907:TEU_RS02870
uniprot id: A0A097QSD1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1505907:TEU RS09035
gene id: 1505907:TEU_RS09035
uniprot id: A0A097QVJ1
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1505907:TEU RS06070
gene id: 1505907:TEU_RS06070
uniprot id: A0A097QU19
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1505907:TEU RS03065
gene id: 1505907:TEU_RS03065
uniprot id: A0A097QSI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane

1505907:TEU RS08205
gene id: 1505907:TEU_RS08205
uniprot id: A0A097QV49
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS01610
gene id: 1505907:TEU_RS01610
uniprot id: A0A097QRN2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TFE family.
messages: Monomer. Interaction with RNA polymerase subunits RpoF and RpoE is necessary for Tfe stimulatory transcription activity. Able to interact with Tbp and RNA polymerase in the absence of DNA promoter. Interacts both with the preinitiation and elongation complexes.
messages: The winged helix domain is involved in binding to DNA in the preinitiation complex.
messages: Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.

1505907:TEU RS01570
gene id: 1505907:TEU_RS01570
uniprot id: A0A097QRM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1505907:TEU RS01590
gene id: 1505907:TEU_RS01590
uniprot id: A0A097QRR1
names: Similarity
messages: Belongs to the acylphosphatase family.

1505907:TEU RS00745
gene id: 1505907:TEU_RS00745
uniprot id: A0A097QR88
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1505907:TEU RS08530
gene id: 1505907:TEU_RS08530
uniprot id: A0A097QVA3
names: Similarity
messages: Belongs to the UPF0127 family.

1505907:TEU RS03540
gene id: 1505907:TEU_RS03540
uniprot id: A0A097QSN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1505907:TEU RS07635
gene id: 1505907:TEU_RS07635
uniprot id: A0A097QUT6
names: Similarity
messages: Belongs to the snRNP Sm proteins family.

1505907:TEU RS11410
gene id: 1505907:TEU_RS11410
uniprot id: A0A097QWW2
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1505907:TEU RS00905
gene id: 1505907:TEU_RS00905
uniprot id: A0A097QRB8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Cytoplasm
messages: Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.

1505907:TEU RS01035
gene id: 1505907:TEU_RS01035
uniprot id: A0A097QRD4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1505907:TEU RS03955
gene id: 1505907:TEU_RS03955
uniprot id: A0A097QSX5
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS05045
gene id: 1505907:TEU_RS05045
uniprot id: A0A097QTH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1505907:TEU RS00760
gene id: 1505907:TEU_RS00760
uniprot id: A0A097QR83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1505907:TEU RS01895
gene id: 1505907:TEU_RS01895
uniprot id: A0A097QRV9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.

1505907:TEU RS10010
gene id: 1505907:TEU_RS10010
uniprot id: A0A097QW33
names: Similarity
messages: Belongs to the UPF0251 family.

1505907:TEU RS03570
gene id: 1505907:TEU_RS03570
uniprot id: A0A097QSP1
names: Function
names: Similarity
messages: Belongs to the UPF0330 family.
messages: Possibly the antitoxin component of a toxin-antitoxin (TA) module.

1505907:TEU RS10515
gene id: 1505907:TEU_RS10515
uniprot id: A0A097QWD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRISPR system Cmr5 family.
messages: Cytoplasm

1505907:TEU RS09295
gene id: 1505907:TEU_RS09295
uniprot id: A0A097QVP1
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1505907:TEU RS08915
gene id: 1505907:TEU_RS08915
uniprot id: A0A097QVH5
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

1505907:TEU RS06120
gene id: 1505907:TEU_RS06120
uniprot id: A0A097QU08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1505907:TEU RS10425
gene id: 1505907:TEU_RS10425
uniprot id: A0A097QWD5
names: Similarity
messages: Belongs to the AOR/FOR family.

1505907:TEU RS02215
gene id: 1505907:TEU_RS02215
uniprot id: A0A097QS09
names: Similarity
messages: Belongs to the UPF0310 family.

1505907:TEU RS02305
gene id: 1505907:TEU_RS02305
uniprot id: A0A097QS16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

1505907:TEU RS09350
gene id: 1505907:TEU_RS09350
uniprot id: A0A097QVQ4
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

1505907:TEU RS07905
gene id: 1505907:TEU_RS07905
uniprot id: A0A097QV01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1505907:TEU RS02170
gene id: 1505907:TEU_RS02170
uniprot id: A0A097QRZ4
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS03935
gene id: 1505907:TEU_RS03935
uniprot id: A0A097QSU7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TYW1 family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
messages: Cytoplasm
messages: Monomer.

1505907:TEU RS06325
gene id: 1505907:TEU_RS06325
uniprot id: A0A097QU44
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal-type GPI family.
messages: Cytoplasm
messages: Homodimer.

1505907:TEU RS05510
gene id: 1505907:TEU_RS05510
uniprot id: A0A097QTN8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

1505907:TEU RS01310
gene id: 1505907:TEU_RS01310
uniprot id: A0A097QRI8
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

1505907:TEU RS11250
gene id: 1505907:TEU_RS11250
uniprot id: A0A097QWQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aTrm56 family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.

1505907:TEU RS05160
gene id: 1505907:TEU_RS05160
uniprot id: A0A097QTI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1505907:TEU RS00895
gene id: 1505907:TEU_RS00895
uniprot id: A0A097QRB1
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS03170
gene id: 1505907:TEU_RS03170
uniprot id: A0A097QSG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1505907:TEU RS01525
gene id: 1505907:TEU_RS01525
uniprot id: A0A097QRM0
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.

1505907:TEU RS09665
gene id: 1505907:TEU_RS09665
uniprot id: A0A097QVV9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeal riboflavin kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1505907:TEU RS01110
gene id: 1505907:TEU_RS01110
uniprot id: A0A097QRG2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SMC family. RAD50 subfamily.
messages: Binds 1 zinc ion per homodimer.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.
messages: The two conserved Cys that bind zinc constitute the zinc-hook, which separates the large intramolecular coiled coil regions. The 2 Cys residues coordinate one molecule of zinc with the help of the 2 Cys residues of the zinc-hook of another Rad50 molecule, thereby forming a V-shaped homodimer.

1505907:TEU RS06490
gene id: 1505907:TEU_RS06490
uniprot id: A0A097QU58
names: Similarity
messages: Belongs to the AOR/FOR family.

1505907:TEU RS11340
gene id: 1505907:TEU_RS11340
uniprot id: A0A097QWQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

1505907:TEU RS07500
gene id: 1505907:TEU_RS07500
uniprot id: A0A097QUR3
names: Similarity
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1505907:TEU RS06230
gene id: 1505907:TEU_RS06230
uniprot id: A0A097QU20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1505907:TEU RS05845
gene id: 1505907:TEU_RS05845
uniprot id: A0A097QTU3
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1505907:TEU RS04465
gene id: 1505907:TEU_RS04465
uniprot id: A0A097QT76
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1505907:TEU RS06125
gene id: 1505907:TEU_RS06125
uniprot id: A0A097QU30
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1505907:TEU RS03105
gene id: 1505907:TEU_RS03105
uniprot id: A0A097QSI0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1505907:TEU RS04560
gene id: 1505907:TEU_RS04560
uniprot id: A0A097QT89
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1505907:TEU RS10015
gene id: 1505907:TEU_RS10015
uniprot id: A0A097QW25
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

1505907:TEU RS08410
gene id: 1505907:TEU_RS08410
uniprot id: A0A097QV85
names: Similarity
messages: Belongs to the UPF0107 family.

1505907:TEU RS05985
gene id: 1505907:TEU_RS05985
uniprot id: A0A097QTY0
names: Similarity
messages: Belongs to the HupF/HypC family.

1505907:TEU RS07570
gene id: 1505907:TEU_RS07570
uniprot id: A0A097QUS4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Potential transporter for phosphate.

1505907:TEU RS03905
gene id: 1505907:TEU_RS03905
uniprot id: A0A097QSX0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Forms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.
messages: Nucleus
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure.

1505907:TEU RS00150
gene id: 1505907:TEU_RS00150
uniprot id: A0A097QQX9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1505907:TEU RS06550
gene id: 1505907:TEU_RS06550
uniprot id: A0A097QU68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1505907:TEU RS00065
gene id: 1505907:TEU_RS00065
uniprot id: A0A097QQU4
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS05735
gene id: 1505907:TEU_RS05735
uniprot id: A0A097QTS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1505907:TEU RS02175
gene id: 1505907:TEU_RS02175
uniprot id: A0A097QS08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1505907:TEU RS02750
gene id: 1505907:TEU_RS02750
uniprot id: A0A097QSA5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1505907:TEU RS05170
gene id: 1505907:TEU_RS05170
uniprot id: A0A097QTJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

1505907:TEU RS09680
gene id: 1505907:TEU_RS09680
uniprot id: A0A097QVW5
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase 2 family.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

1505907:TEU RS07215
gene id: 1505907:TEU_RS07215
uniprot id: A0A097QUK6
names: Similarity
messages: Belongs to the peptidase S49 family.

1505907:TEU RS07120
gene id: 1505907:TEU_RS07120
uniprot id: A0A097QUL7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the GatB/GatE family. GatE subfamily.
messages: Heterodimer of GatD and GatE.

1505907:TEU RS00320
gene id: 1505907:TEU_RS00320
uniprot id: A0A097QQZ9
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS02630
gene id: 1505907:TEU_RS02630
uniprot id: A0A097QS83
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

1505907:TEU RS05575
gene id: 1505907:TEU_RS05575
uniprot id: A0A097QTR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1505907:TEU RS01735
gene id: 1505907:TEU_RS01735
uniprot id: A0A097QRQ8
names: Similarity
messages: Belongs to the class-I fumarase family.

1505907:TEU RS05375
gene id: 1505907:TEU_RS05375
uniprot id: A0A097QTN4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer.

1505907:TEU RS11300
gene id: 1505907:TEU_RS11300
uniprot id: A0A097QWU2
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS10140
gene id: 1505907:TEU_RS10140
uniprot id: A0A097QW51
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1505907:TEU RS06910
gene id: 1505907:TEU_RS06910
uniprot id: A0A097QUF0
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS09575
gene id: 1505907:TEU_RS09575
uniprot id: A0A097QVV0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1505907:TEU RS01190
gene id: 1505907:TEU_RS01190
uniprot id: A0A097QRH6
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Heterooligomer of catalytic and regulatory chains.

1505907:TEU RS05185
gene id: 1505907:TEU_RS05185
uniprot id: A0A097QTK6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

1505907:TEU RS03945
gene id: 1505907:TEU_RS03945
uniprot id: A0A097QSU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

1505907:TEU RS10630
gene id: 1505907:TEU_RS10630
uniprot id: A0A097QWF2
names: Function
names: Similarity
messages: Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently.
messages: Belongs to the archease family.

1505907:TEU RS08875
gene id: 1505907:TEU_RS08875
uniprot id: A0A097QVG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1505907:TEU RS03075
gene id: 1505907:TEU_RS03075
uniprot id: A0A097QSH2
names: Function
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1505907:TEU RS06700
gene id: 1505907:TEU_RS06700
uniprot id: A0A097QUB1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1505907:TEU RS09565
gene id: 1505907:TEU_RS09565
uniprot id: A0A097QVU7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1505907:TEU RS05715
gene id: 1505907:TEU_RS05715
uniprot id: A0A097QTS1
names: Similarity
messages: Belongs to the thymidylate kinase family.

1505907:TEU RS01600
gene id: 1505907:TEU_RS01600
uniprot id: A0A097QRN5
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1505907:TEU RS05925
gene id: 1505907:TEU_RS05925
uniprot id: A0A097QTW2
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS05650
gene id: 1505907:TEU_RS05650
uniprot id: A0A097QTU1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1505907:TEU RS06445
gene id: 1505907:TEU_RS06445
uniprot id: A0A097QU57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms part of the jaw domain.
messages: Part of the RNA polymerase complex.

1505907:TEU RS08405
gene id: 1505907:TEU_RS08405
uniprot id: A0A097QV73
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS10030
gene id: 1505907:TEU_RS10030
uniprot id: A0A097QW21
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.
messages: Belongs to the histone-like Alba family.
messages: Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.
messages: Chromosome
messages: Cytoplasm
messages: Homotetramer.

1505907:TEU RS06765
gene id: 1505907:TEU_RS06765
uniprot id: A0A097QUD6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1505907:TEU RS04975
gene id: 1505907:TEU_RS04975
uniprot id: A0A097QTG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e.

1505907:TEU RS01580
gene id: 1505907:TEU_RS01580
uniprot id: A0A097QRN0
names: Similarity
messages: Belongs to the UPF0215 family.

1505907:TEU RS04130
gene id: 1505907:TEU_RS04130
uniprot id: A0A097QT02
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1505907:TEU RS05440
gene id: 1505907:TEU_RS05440
uniprot id: A0A097QTP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

1505907:TEU RS06715
gene id: 1505907:TEU_RS06715
uniprot id: A0A097QUA5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

1505907:TEU RS07020
gene id: 1505907:TEU_RS07020
uniprot id: A0A097QUJ7
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS05125
gene id: 1505907:TEU_RS05125
uniprot id: A0A097QTJ6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
messages: Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1505907:TEU RS04895
gene id: 1505907:TEU_RS04895
uniprot id: A0A097QTD0
names: Similarity
messages: Belongs to the UPF0045 family.

1505907:TEU RS10695
gene id: 1505907:TEU_RS10695
uniprot id: A0A097QWE9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1505907:TEU RS07030
gene id: 1505907:TEU_RS07030
uniprot id: A0A097QUH0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1505907:TEU RS08290
gene id: 1505907:TEU_RS08290
uniprot id: A0A097QV59
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1505907:TEU RS05095
gene id: 1505907:TEU_RS05095
uniprot id: A0A097QTJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1505907:TEU RS07190
gene id: 1505907:TEU_RS07190
uniprot id: A0A097QUK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta-RFA-P synthase family.
messages: Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
messages: Homodimer.

1505907:TEU RS10305
gene id: 1505907:TEU_RS10305
uniprot id: A0A097QW91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6B family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

1505907:TEU RS01930
gene id: 1505907:TEU_RS01930
uniprot id: A0A097QRU8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1505907:TEU RS05335
gene id: 1505907:TEU_RS05335
uniprot id: A0A097QTN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
messages: Cytoplasm

1505907:TEU RS06720
gene id: 1505907:TEU_RS06720
uniprot id: A0A097QUC5
names: Function
names: Similarity
messages: Belongs to the archaeal SPP-like hydrolase family.
messages: Catalyzes the dephosphorylation of 2-phosphoglycolate.

1505907:TEU RS10735
gene id: 1505907:TEU_RS10735
uniprot id: A0A097QWF5
names: Caution
names: Function
names: Similarity
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1505907:TEU RS07965
gene id: 1505907:TEU_RS07965
uniprot id: A0A097QUZ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

1505907:TEU RS06620
gene id: 1505907:TEU_RS06620
uniprot id: A0A097QUC2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Both the DNA unwinding and positive supercoiling activities require the cooperation of both domains. The cooperative action between the helicase-like and the topoisomerase domains is specific. The helicase-like domain probably does not directly unwind DNA but acts more likely by driving ATP-dependent conformational changes within the whole enzyme, functioning more like a protein motor. The 'latch' region of the N-terminal domain plays a regulatory role in the enzyme, repressing topoisomerase activity in the absence of ATP and therefore preventing the enzyme from acting as an ATP-independent relaxing enzyme; it also helps to coordinate nucleotide hydrolysis by the ATPase domain with the supercoiling activity of the topoisomerase domain.
messages: In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
messages: In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily.
messages: Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
messages: Monomer.
messages: This enzyme is the only unique feature of hyperthermophilic bacteria/archaea discovered so far. It appears to be essential for adaptation to life at high temperatures.

1505907:TEU RS09195
gene id: 1505907:TEU_RS09195
uniprot id: A0A097QVM1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1505907:TEU RS08335
gene id: 1505907:TEU_RS08335
uniprot id: A0A097QV69
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1505907:TEU RS02955
gene id: 1505907:TEU_RS02955
uniprot id: A0A097QSD7
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1505907:TEU RS05705
gene id: 1505907:TEU_RS05705
uniprot id: A0A097QTT6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1505907:TEU RS06560
gene id: 1505907:TEU_RS06560
uniprot id: A0A097QU90
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1505907:TEU RS04025
gene id: 1505907:TEU_RS04025
uniprot id: A0A097QSY6
names: Similarity
messages: Belongs to the peptidase C56 family.

1505907:TEU RS01585
gene id: 1505907:TEU_RS01585
uniprot id: A0A097QRM7
names: Similarity
messages: Belongs to the CutA family.

1505907:TEU RS05120
gene id: 1505907:TEU_RS05120
uniprot id: A0A097QTJ4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

1505907:TEU RS07160
gene id: 1505907:TEU_RS07160
uniprot id: A0A097QUJ2
names: Caution
names: Function
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1505907:TEU RS04225
gene id: 1505907:TEU_RS04225
uniprot id: A0A097QT19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC61-beta family.
messages: Cell membrane
messages: Component of the protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. Can form oligomers of the heterotrimer.
messages: Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.
messages: Membrane

1505907:TEU RS01505
gene id: 1505907:TEU_RS01505
uniprot id: A0A097QRL7
names: Similarity
messages: Belongs to the archaeosine synthase type 1 family.

1505907:TEU RS00445
gene id: 1505907:TEU_RS00445
uniprot id: A0A097QR25
names: Cofactor
names: Similarity
messages: Belongs to the PdaD family.
messages: Binds 1 pyruvoyl group covalently per subunit.

1505907:TEU RS02585
gene id: 1505907:TEU_RS02585
uniprot id: A0A097QS76
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1505907:TEU RS01545
gene id: 1505907:TEU_RS01545
uniprot id: A0A097QRM3
names: Similarity
messages: Belongs to the AOR/FOR family.

1505907:TEU RS10925
gene id: 1505907:TEU_RS10925
uniprot id: A0A097QWL1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1505907:TEU RS07630
gene id: 1505907:TEU_RS07630
uniprot id: A0A097QUT8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

1505907:TEU RS03660
gene id: 1505907:TEU_RS03660
uniprot id: A0A097QSP7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1505907:TEU RS07090
gene id: 1505907:TEU_RS07090
uniprot id: A0A097QUI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure.

1505907:TEU RS08635
gene id: 1505907:TEU_RS08635
uniprot id: A0A097QVD2
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS10360
gene id: 1505907:TEU_RS10360
uniprot id: A0A097QW89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

1505907:TEU RS04995
gene id: 1505907:TEU_RS04995
uniprot id: A0A097QTG9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1505907:TEU RS05030
gene id: 1505907:TEU_RS05030
uniprot id: A0A097QTF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.

1505907:TEU RS08525
gene id: 1505907:TEU_RS08525
uniprot id: A0A097QVA5
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1505907:TEU RS10545
gene id: 1505907:TEU_RS10545
uniprot id: A0A097QWC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1505907:TEU RS09425
gene id: 1505907:TEU_RS09425
uniprot id: A0A097QVS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

1505907:TEU RS00490
gene id: 1505907:TEU_RS00490
uniprot id: A0A097QR41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1505907:TEU RS10830
gene id: 1505907:TEU_RS10830
uniprot id: A0A097QWH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 'phage' integrase family. XerA subfamily.
messages: Cytoplasm
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1505907:TEU RS04145
gene id: 1505907:TEU_RS04145
uniprot id: A0A097QT08
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1505907:TEU RS00005
gene id: 1505907:TEU_RS00005
uniprot id: A0A097QWT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1505907:TEU RS01730
gene id: 1505907:TEU_RS01730
uniprot id: A0A097QRR2
names: Similarity
messages: Belongs to the class-I fumarase family.

1505907:TEU RS06940
gene id: 1505907:TEU_RS06940
uniprot id: A0A097QUF5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

1505907:TEU RS02580
gene id: 1505907:TEU_RS02580
uniprot id: A0A097QS72
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS06595
gene id: 1505907:TEU_RS06595
uniprot id: A0A097QUB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1505907:TEU RS05055
gene id: 1505907:TEU_RS05055
uniprot id: A0A097QTG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

1505907:TEU RS03440
gene id: 1505907:TEU_RS03440
uniprot id: A0A097QSL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1505907:TEU RS10615
gene id: 1505907:TEU_RS10615
uniprot id: A0A097QWE2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1505907:TEU RS05035
gene id: 1505907:TEU_RS05035
uniprot id: A0A097QTF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: Located at the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1505907:TEU RS05115
gene id: 1505907:TEU_RS05115
uniprot id: A0A097QTI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

1505907:TEU RS05380
gene id: 1505907:TEU_RS05380
uniprot id: A0A097QTN5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1505907:TEU RS08535
gene id: 1505907:TEU_RS08535
uniprot id: A0A097QVB2
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1505907:TEU RS06710
gene id: 1505907:TEU_RS06710
uniprot id: A0A097QUA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTH2 family.
messages: Cytoplasm
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1505907:TEU RS00400
gene id: 1505907:TEU_RS00400
uniprot id: A0A097QR08
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1505907:TEU RS04960
gene id: 1505907:TEU_RS04960
uniprot id: A0A097QTF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diphthine synthase family.
messages: Homodimer.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.

1505907:TEU RS03495
gene id: 1505907:TEU_RS03495
uniprot id: A0A097QSQ8
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

1505907:TEU RS03455
gene id: 1505907:TEU_RS03455
uniprot id: A0A097QSM3
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

1505907:TEU RS00425
gene id: 1505907:TEU_RS00425
uniprot id: A0A097QR13
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS04990
gene id: 1505907:TEU_RS04990
uniprot id: A0A097QTF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1505907:TEU RS04480
gene id: 1505907:TEU_RS04480
uniprot id: A0A097QT63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched-chain polyamine synthase family.
messages: Cytoplasm
messages: Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.

1505907:TEU RS03560
gene id: 1505907:TEU_RS03560
uniprot id: A0A097QSR8
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

1505907:TEU RS04855
gene id: 1505907:TEU_RS04855
uniprot id: A0A097QTE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1505907:TEU RS00800
gene id: 1505907:TEU_RS00800
uniprot id: A0A097QR84
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1505907:TEU RS07590
gene id: 1505907:TEU_RS07590
uniprot id: A0A097QUU9
names: Similarity
messages: Belongs to the peptidase M24B family.

1505907:TEU RS10455
gene id: 1505907:TEU_RS10455
uniprot id: A0A097QW99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclic 2,3-diphosphoglycerate synthetase family.
messages: Catalyzes the formation of cyclic 2,3-diphosphoglycerate (cDPG) by formation of an intramolecular phosphoanhydride bond at the expense of ATP.
messages: Cytoplasm

1505907:TEU RS10745
gene id: 1505907:TEU_RS10745
uniprot id: A0A097QWF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1505907:TEU RS07270
gene id: 1505907:TEU_RS07270
uniprot id: A0A097QUL5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.
messages: Belongs to the Holliday junction resolvase Hjc family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.

1505907:TEU RS00815
gene id: 1505907:TEU_RS00815
uniprot id: A0A097QR91
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72.

1505907:TEU RS06435
gene id: 1505907:TEU_RS06435
uniprot id: A0A097QU87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1505907:TEU RS10645
gene id: 1505907:TEU_RS10645
uniprot id: A0A097QWH5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

1505907:TEU RS09060
gene id: 1505907:TEU_RS09060
uniprot id: A0A097QVJ6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1505907:TEU RS02040
gene id: 1505907:TEU_RS02040
uniprot id: A0A097QRW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1505907:TEU RS05665
gene id: 1505907:TEU_RS05665
uniprot id: A0A097QTT2
names: Similarity
messages: Belongs to the UPF0292 family.

1505907:TEU RS06935
gene id: 1505907:TEU_RS06935
uniprot id: A0A097QUF3
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS06300
gene id: 1505907:TEU_RS06300
uniprot id: A0A097QU38
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS00755
gene id: 1505907:TEU_RS00755
uniprot id: A0A097QR94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1505907:TEU RS04740
gene id: 1505907:TEU_RS04740
uniprot id: A0A097QTA1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1505907:TEU RS05530
gene id: 1505907:TEU_RS05530
uniprot id: A0A097QTP1
names: Similarity
messages: Belongs to the P(II) protein family.

1505907:TEU RS01670
gene id: 1505907:TEU_RS01670
uniprot id: A0A097QRP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1505907:TEU RS10905
gene id: 1505907:TEU_RS10905
uniprot id: A0A097QWI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

1505907:TEU RS05025
gene id: 1505907:TEU_RS05025
uniprot id: A0A097QTH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1505907:TEU RS07105
gene id: 1505907:TEU_RS07105
uniprot id: A0A097QUI2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.
messages: Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

1505907:TEU RS07230
gene id: 1505907:TEU_RS07230
uniprot id: A0A097QUK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1505907:TEU RS02520
gene id: 1505907:TEU_RS02520
uniprot id: A0A097QS58
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS10945
gene id: 1505907:TEU_RS10945
uniprot id: A0A097QWJ9
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS05360
gene id: 1505907:TEU_RS05360
uniprot id: A0A097QTN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isopentenyl phosphate kinase family.
messages: Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids.
messages: Homodimer.

1505907:TEU RS02735
gene id: 1505907:TEU_RS02735
uniprot id: A0A097QSA2
names: Function
names: Similarity
messages: Belongs to the group II decarboxylase family. MfnA subfamily.
messages: Catalyzes the decarboxylation of L-aspartate to produce beta-alanine.

1505907:TEU RS01660
gene id: 1505907:TEU_RS01660
uniprot id: A0A097QRP2
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1505907:TEU RS00060
gene id: 1505907:TEU_RS00060
uniprot id: A0A097QQW2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1505907:TEU RS10700
gene id: 1505907:TEU_RS10700
uniprot id: A0A097QWF4
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS05630
gene id: 1505907:TEU_RS05630
uniprot id: A0A097QTR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. Probably involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.
messages: Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.

1505907:TEU RS06335
gene id: 1505907:TEU_RS06335
uniprot id: A0A097QU66
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1505907:TEU RS01345
gene id: 1505907:TEU_RS01345
uniprot id: A0A097QRJ0
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72.

1505907:TEU RS00255
gene id: 1505907:TEU_RS00255
uniprot id: A0A097QR00
names: Similarity
messages: Belongs to the UPF0128 family.

1505907:TEU RS01710
gene id: 1505907:TEU_RS01710
uniprot id: A0A097QRQ4
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1505907:TEU RS06875
gene id: 1505907:TEU_RS06875
uniprot id: A0A097QUE6
names: Similarity
messages: Belongs to the AOR/FOR family.

1505907:TEU RS00585
gene id: 1505907:TEU_RS00585
uniprot id: A0A097QR47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.
messages: Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.
messages: Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

1505907:TEU RS07145
gene id: 1505907:TEU_RS07145
uniprot id: A0A097QUJ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

1505907:TEU RS06075
gene id: 1505907:TEU_RS06075
uniprot id: A0A097QTZ0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1505907:TEU RS05410
gene id: 1505907:TEU_RS05410
uniprot id: A0A097QTP0
names: Similarity
messages: Belongs to the peptidase M24B family.

1505907:TEU RS00875
gene id: 1505907:TEU_RS00875
uniprot id: A0A097QR98
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1505907:TEU RS07240
gene id: 1505907:TEU_RS07240
uniprot id: A0A097QUL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSL4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. Interacts with DnaG.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.

1505907:TEU RS06145
gene id: 1505907:TEU_RS06145
uniprot id: A0A097QU13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.
messages: Membrane

1505907:TEU RS01465
gene id: 1505907:TEU_RS01465
uniprot id: A0A097QRL1
names: Subunit
messages: Homotetramer.

1505907:TEU RS05285
gene id: 1505907:TEU_RS05285
uniprot id: A0A097QTJ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

1505907:TEU RS09135
gene id: 1505907:TEU_RS09135
uniprot id: A0A097QVM2
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1505907:TEU RS04685
gene id: 1505907:TEU_RS04685
uniprot id: A0A097QT92
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1505907:TEU RS06750
gene id: 1505907:TEU_RS06750
uniprot id: A0A097QUA9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1505907:TEU RS07565
gene id: 1505907:TEU_RS07565
uniprot id: A0A097QUU6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeosine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.

1505907:TEU RS07095
gene id: 1505907:TEU_RS07095
uniprot id: A0A097QUL2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

1505907:TEU RS00955
gene id: 1505907:TEU_RS00955
uniprot id: A0A097QRC8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1505907:TEU RS06060
gene id: 1505907:TEU_RS06060
uniprot id: A0A097QTZ7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1505907:TEU RS06760
gene id: 1505907:TEU_RS06760
uniprot id: A0A097QUC0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1505907:TEU RS06665
gene id: 1505907:TEU_RS06665
uniprot id: A0A097QU95
names: Similarity
messages: Belongs to the HPS/KGPDC family. HPS subfamily.
messages: Belongs to the SIS family. PHI subfamily.

1505907:TEU RS01175
gene id: 1505907:TEU_RS01175
uniprot id: A0A097QRF4
names: Similarity
messages: Belongs to the UPF0047 family.

1505907:TEU RS09210
gene id: 1505907:TEU_RS09210
uniprot id: A0A097QVN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1505907:TEU RS08860
gene id: 1505907:TEU_RS08860
uniprot id: A0A097QVG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Cytoplasm
messages: Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
messages: Part of the 50S ribosomal subunit. Probably part of the RNase P complex.

1505907:TEU RS06115
gene id: 1505907:TEU_RS06115
uniprot id: A0A097QU06
names: Similarity
messages: Belongs to the UPF0175 family.

1505907:TEU RS06340
gene id: 1505907:TEU_RS06340
uniprot id: A0A097QU31
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1505907:TEU RS00460
gene id: 1505907:TEU_RS00460
uniprot id: A0A097QR36
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS06330
gene id: 1505907:TEU_RS06330
uniprot id: A0A097QU43
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADP-dependent glucokinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the ADP-dependent phosphorylation of D-glucose to D-glucose 6-phosphate and glucosamine to glucosamine 6-phosphate.
messages: Cytoplasm

1505907:TEU RS06450
gene id: 1505907:TEU_RS06450
uniprot id: A0A097QU70
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

1505907:TEU RS01695
gene id: 1505907:TEU_RS01695
uniprot id: A0A097QRQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

1505907:TEU RS11260
gene id: 1505907:TEU_RS11260
uniprot id: A0A097QWP0
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Catalyzes the dephosphorylation of D,L-glyceraldehyde 3-phosphate in vitro.

1505907:TEU RS05595
gene id: 1505907:TEU_RS05595
uniprot id: A0A097QTT0
names: Function
names: Similarity
messages: Belongs to the HARP family.
messages: RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.

1505907:TEU RS03445
gene id: 1505907:TEU_RS03445
uniprot id: A0A097QSP8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

1505907:TEU RS11390
gene id: 1505907:TEU_RS11390
uniprot id: A0A097QWU5
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1505907:TEU RS03090
gene id: 1505907:TEU_RS03090
uniprot id: A0A097QSI9
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.

1505907:TEU RS03525
gene id: 1505907:TEU_RS03525
uniprot id: A0A097QSM4
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1505907:TEU RS10375
gene id: 1505907:TEU_RS10375
uniprot id: A0A097QW83
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

1505907:TEU RS05190
gene id: 1505907:TEU_RS05190
uniprot id: A0A097QTI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1505907:TEU RS00085
gene id: 1505907:TEU_RS00085
uniprot id: A0A097QQW7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family. WtpA subfamily.

1505907:TEU RS06485
gene id: 1505907:TEU_RS06485
uniprot id: A0A097QU96
names: Caution
names: Function
names: Similarity
messages: Belongs to the Nre family.
messages: Involved in DNA damage repair.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1505907:TEU RS09710
gene id: 1505907:TEU_RS09710
uniprot id: A0A097QW03
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1505907:TEU RS07895
gene id: 1505907:TEU_RS07895
uniprot id: A0A097QUY3
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1505907:TEU RS01410
gene id: 1505907:TEU_RS01410
uniprot id: A0A097QRK3
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. PoK subfamily.
messages: Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway.

1505907:TEU RS11335
gene id: 1505907:TEU_RS11335
uniprot id: A0A097QWT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

1505907:TEU RS10385
gene id: 1505907:TEU_RS10385
uniprot id: A0A097QW93
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. TrmY family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.

1505907:TEU RS08865
gene id: 1505907:TEU_RS08865
uniprot id: A0A097QVH3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

1505907:TEU RS06260
gene id: 1505907:TEU_RS06260
uniprot id: A0A097QU24
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS07050
gene id: 1505907:TEU_RS07050
uniprot id: A0A097QUH5
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1505907:TEU RS08640
gene id: 1505907:TEU_RS08640
uniprot id: A0A097QVD4
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS01420
gene id: 1505907:TEU_RS01420
uniprot id: A0A097QRK5
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

1505907:TEU RS01650
gene id: 1505907:TEU_RS01650
uniprot id: A0A097QRP6
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1505907:TEU RS03535
gene id: 1505907:TEU_RS03535
uniprot id: A0A097QSR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1505907:TEU RS04435
gene id: 1505907:TEU_RS04435
uniprot id: A0A097QT53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal phosphopantothenate synthetase family.
messages: Catalyzes the condensation of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway.
messages: Homodimer.

1505907:TEU RS00575
gene id: 1505907:TEU_RS00575
uniprot id: A0A097QR58
names: Similarity
messages: Belongs to the thiolase-like superfamily. UPF0219 family.

1505907:TEU RS08305
gene id: 1505907:TEU_RS08305
uniprot id: A0A097QV57
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1505907:TEU RS06540
gene id: 1505907:TEU_RS06540
uniprot id: A0A097QU84
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1505907:TEU RS05100
gene id: 1505907:TEU_RS05100
uniprot id: A0A097QTI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal adenylate kinase family.
messages: Cytoplasm

1505907:TEU RS09800
gene id: 1505907:TEU_RS09800
uniprot id: A0A097QVZ1
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family.

1505907:TEU RS00530
gene id: 1505907:TEU_RS00530
uniprot id: A0A097QR39
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.

1505907:TEU RS00605
gene id: 1505907:TEU_RS00605
uniprot id: A0A097QR55
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. R15P isomerase subfamily.
messages: Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO. Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO.
messages: Reaction proceeds via a cis-phosphoenolate intermediate.

1505907:TEU RS04270
gene id: 1505907:TEU_RS04270
uniprot id: A0A097QT21
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS03920
gene id: 1505907:TEU_RS03920
uniprot id: A0A097QST6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

1505907:TEU RS03820
gene id: 1505907:TEU_RS03820
uniprot id: A0A097QSW9
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1505907:TEU RS10590
gene id: 1505907:TEU_RS10590
uniprot id: A0A097QWG5
names: Similarity
messages: Belongs to the IMPACT family.

1505907:TEU RS07825
gene id: 1505907:TEU_RS07825
uniprot id: A0A097QUW9
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS03910
gene id: 1505907:TEU_RS03910
uniprot id: A0A097QSU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Spt4 family.
messages: Heterodimer composed of Spt4 and Spt5.
messages: Stimulates transcription elongation.

1505907:TEU RS09175
gene id: 1505907:TEU_RS09175
uniprot id: A0A097QVM4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1505907:TEU RS09695
gene id: 1505907:TEU_RS09695
uniprot id: A0A097QVX0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1505907:TEU RS03995
gene id: 1505907:TEU_RS03995
uniprot id: A0A097QSV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1505907:TEU RS10145
gene id: 1505907:TEU_RS10145
uniprot id: A0A097QW62
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1505907:TEU RS05040
gene id: 1505907:TEU_RS05040
uniprot id: A0A097QTG8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

1505907:TEU RS10105
gene id: 1505907:TEU_RS10105
uniprot id: A0A097QW36
names: Similarity
messages: Belongs to the UPF0248 family.

1505907:TEU RS07755
gene id: 1505907:TEU_RS07755
uniprot id: A0A097QUV9
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Catalyzes the dephosphorylation of D,L-glyceraldehyde 3-phosphate in vitro.

1505907:TEU RS06425
gene id: 1505907:TEU_RS06425
uniprot id: A0A097QU65
names: Similarity
messages: Belongs to the glutaredoxin family.

1505907:TEU RS08395
gene id: 1505907:TEU_RS08395
uniprot id: A0A097QV86
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS06515
gene id: 1505907:TEU_RS06515
uniprot id: A0A097QU80
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1505907:TEU RS05545
gene id: 1505907:TEU_RS05545
uniprot id: A0A097QTR2
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

1505907:TEU RS11345
gene id: 1505907:TEU_RS11345
uniprot id: A0A097QWR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

1505907:TEU RS04235
gene id: 1505907:TEU_RS04235
uniprot id: A0A097QT38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

1505907:TEU RS03710
gene id: 1505907:TEU_RS03710
uniprot id: A0A097QSV8
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS08545
gene id: 1505907:TEU_RS08545
uniprot id: A0A097QVA0
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1505907:TEU RS07740
gene id: 1505907:TEU_RS07740
uniprot id: A0A097QUV8
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS09755
gene id: 1505907:TEU_RS09755
uniprot id: A0A097QVX8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1505907:TEU RS02625
gene id: 1505907:TEU_RS02625
uniprot id: A0A097QS80
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1505907:TEU RS01280
gene id: 1505907:TEU_RS01280
uniprot id: A0A097QRH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S16 family.
messages: Membrane

1505907:TEU RS01665
gene id: 1505907:TEU_RS01665
uniprot id: A0A097QRS3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Potential transporter for phosphate.

1505907:TEU RS00735
gene id: 1505907:TEU_RS00735
uniprot id: A0A097QR82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1505907:TEU RS02895
gene id: 1505907:TEU_RS02895
uniprot id: A0A097QSD3
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS09165
gene id: 1505907:TEU_RS09165
uniprot id: A0A097QVM8
names: Similarity
messages: Belongs to the UPF0166 family.

1505907:TEU RS03080
gene id: 1505907:TEU_RS03080
uniprot id: A0A097QSH5
names: Function
names: Similarity
messages: Belongs to the V-ATPase F subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1505907:TEU RS02535
gene id: 1505907:TEU_RS02535
uniprot id: A0A097QS74
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1505907:TEU RS01875
gene id: 1505907:TEU_RS01875
uniprot id: A0A097QRT9
names: Similarity
messages: Belongs to the UPF0111 family.

1505907:TEU RS04770
gene id: 1505907:TEU_RS04770
uniprot id: A0A097QTB9
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

1505907:TEU RS07245
gene id: 1505907:TEU_RS07245
uniprot id: A0A097QUL0
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1505907:TEU RS02185
gene id: 1505907:TEU_RS02185
uniprot id: A0A097QRZ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Monomer. Component of the KEOPS complex that consists of Kae1, Bud32, Cgi121 and Pcc1; the whole complex dimerizes.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.

1505907:TEU RS07950
gene id: 1505907:TEU_RS07950
uniprot id: A0A097QUZ4
names: Similarity
messages: Belongs to the peptidase S9C family.

1505907:TEU RS01940
gene id: 1505907:TEU_RS01940
uniprot id: A0A097QRU7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1505907:TEU RS01165
gene id: 1505907:TEU_RS01165
uniprot id: A0A097QRH1
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

1505907:TEU RS10355
gene id: 1505907:TEU_RS10355
uniprot id: A0A097QWA1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1505907:TEU RS02390
gene id: 1505907:TEU_RS02390
uniprot id: A0A097QS36
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1505907:TEU RS05640
gene id: 1505907:TEU_RS05640
uniprot id: A0A097QTS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

1505907:TEU RS08505
gene id: 1505907:TEU_RS08505
uniprot id: A0A097QV98
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1505907:TEU RS06350
gene id: 1505907:TEU_RS06350
uniprot id: A0A097QU51
names: Function
names: Similarity
messages: Belongs to the NOP10 family.
messages: Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.

1505907:TEU RS10300
gene id: 1505907:TEU_RS10300
uniprot id: A0A097QW68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6A family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

1505907:TEU RS00325
gene id: 1505907:TEU_RS00325
uniprot id: A0A097QQZ2
names: Similarity
messages: Belongs to the UPF0201 family.

1505907:TEU RS07415
gene id: 1505907:TEU_RS07415
uniprot id: A0A097QUP2
names: Similarity
messages: Belongs to the HerA family.

1505907:TEU RS04875
gene id: 1505907:TEU_RS04875
uniprot id: A0A097QTD6
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

1505907:TEU RS05625
gene id: 1505907:TEU_RS05625
uniprot id: A0A097QTQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1505907:TEU RS11255
gene id: 1505907:TEU_RS11255
uniprot id: A0A097QWR9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Binds 2 Mg(2+) or Mn(2+) ions per subunit.
messages: Catalyzes the formation of archaetidylinositol phosphate (AIP) from CDP-archaeol (CDP-ArOH or CDP-2,3-bis-(O-phytanyl)-sn-glycerol) and 1L-myo-inositol 1-phosphate (IP or 1D-myo-inositol 3-phosphate). AIP is a precursor of archaetidyl-myo-inositol (AI), an ether-type inositol phospholipid ubiquitously distributed in archaea membranes and essential for glycolipid biosynthesis in archaea.
messages: Cell membrane

1505907:TEU RS05010
gene id: 1505907:TEU_RS05010
uniprot id: A0A097QTE7
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1505907:TEU RS07705
gene id: 1505907:TEU_RS07705
uniprot id: A0A097QUV5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1505907:TEU RS04450
gene id: 1505907:TEU_RS04450
uniprot id: A0A097QT52
names: Similarity
messages: Belongs to the UPF0282 family.

1505907:TEU RS01090
gene id: 1505907:TEU_RS01090
uniprot id: A0A097QRE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA-intron endonuclease family. Archaeal short subfamily.
messages: Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
messages: Homotetramer; although the tetramer contains four active sites, only two participate in the cleavage. Therefore, it should be considered as a dimer of dimers.

1505907:TEU RS07690
gene id: 1505907:TEU_RS07690
uniprot id: A0A097QUW8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1505907:TEU RS06460
gene id: 1505907:TEU_RS06460
uniprot id: A0A097QU92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Part of the 30S ribosomal subunit.
messages: With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.

1505907:TEU RS05050
gene id: 1505907:TEU_RS05050
uniprot id: A0A097QTH9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles.
messages: Part of the 30S ribosomal subunit.

1505907:TEU RS00785
gene id: 1505907:TEU_RS00785
uniprot id: A0A097QR92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1505907:TEU RS03205
gene id: 1505907:TEU_RS03205
uniprot id: A0A097QSJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase small subunit family.
messages: Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1505907:TEU RS04355
gene id: 1505907:TEU_RS04355
uniprot id: A0A097QT56
names: Similarity
messages: Belongs to the UPF0145 family.

1505907:TEU RS10210
gene id: 1505907:TEU_RS10210
uniprot id: A0A097QW59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1505907:TEU RS05635
gene id: 1505907:TEU_RS05635
uniprot id: A0A097QTS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

1505907:TEU RS04015
gene id: 1505907:TEU_RS04015
uniprot id: A0A097QSY8
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS01985
gene id: 1505907:TEU_RS01985
uniprot id: A0A097QRV1
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS01365
gene id: 1505907:TEU_RS01365
uniprot id: A0A097QRJ6
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS10410
gene id: 1505907:TEU_RS10410
uniprot id: A0A097QWB2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

1505907:TEU RS07380
gene id: 1505907:TEU_RS07380
uniprot id: A0A097QUN5
names: Similarity
messages: Belongs to the MCM family.

1505907:TEU RS00770
gene id: 1505907:TEU_RS00770
uniprot id: A0A097QR97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

1505907:TEU RS05175
gene id: 1505907:TEU_RS05175
uniprot id: A0A097QTK5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the RNA polymerase complex.

1505907:TEU RS01140
gene id: 1505907:TEU_RS01140
uniprot id: A0A097QRF3
names: Similarity
messages: Belongs to the threonine synthase family.

1505907:TEU RS06085
gene id: 1505907:TEU_RS06085
uniprot id: A0A097QU02
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1505907:TEU RS06080
gene id: 1505907:TEU_RS06080
uniprot id: A0A097QTZ4
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS07680
gene id: 1505907:TEU_RS07680
uniprot id: A0A097QUV0
names: Subcellular Location Annotation
messages: Cytoplasm

1505907:TEU RS07660
gene id: 1505907:TEU_RS07660
uniprot id: A0A097QUU2
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.
messages: Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.

1505907:TEU RS00045
gene id: 1505907:TEU_RS00045
uniprot id: A0A097QQV2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
messages: Binds 1 zinc ion per subunit.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

1505907:TEU RS09415
gene id: 1505907:TEU_RS09415
uniprot id: A0A097QVS8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS1 family.

1505907:TEU RS09810
gene id: 1505907:TEU_RS09810
uniprot id: A0A097QVZ0
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS01265
gene id: 1505907:TEU_RS01265
uniprot id: A0A097QRI2
names: Similarity
messages: Belongs to the peptidase U62 family.

1505907:TEU RS08065
gene id: 1505907:TEU_RS08065
uniprot id: A0A097QV17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1505907:TEU RS09855
gene id: 1505907:TEU_RS09855
uniprot id: A0A097QVZ8
names: Similarity
messages: Belongs to the PDCD5 family.

1505907:TEU RS00640
gene id: 1505907:TEU_RS00640
uniprot id: A0A097QR69
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the UPF0165 family.

1505907:TEU RS10485
gene id: 1505907:TEU_RS10485
uniprot id: A0A097QWC6
names: Similarity
messages: Belongs to the HypE family.

1505907:TEU RS07260
gene id: 1505907:TEU_RS07260
uniprot id: A0A097QUL3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1505907:TEU RS00485
gene id: 1505907:TEU_RS00485
uniprot id: A0A097QR27
names: Similarity
messages: Belongs to the UPF0173 family.

1505907:TEU RS08490
gene id: 1505907:TEU_RS08490
uniprot id: A0A097QVA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1505907:TEU RS00995
gene id: 1505907:TEU_RS00995
uniprot id: A0A097QRD6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class III (archaeal) subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1505907:TEU RS05680
gene id: 1505907:TEU_RS05680
uniprot id: A0A097QTU7
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

1505907:TEU RS08895
gene id: 1505907:TEU_RS08895
uniprot id: A0A097QVH7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1505907:TEU RS07000
gene id: 1505907:TEU_RS07000
uniprot id: A0A097QUG5
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1505907:TEU RS05165
gene id: 1505907:TEU_RS05165
uniprot id: A0A097QTH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1505907:TEU RS09510
gene id: 1505907:TEU_RS09510
uniprot id: A0A097QVU0
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1505907:TEU RS08255
gene id: 1505907:TEU_RS08255
uniprot id: A0A097QV46
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

1505907:TEU RS05655
gene id: 1505907:TEU_RS05655
uniprot id: A0A097QTQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

1505907:TEU RS04305
gene id: 1505907:TEU_RS04305
uniprot id: A0A097QT33
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1505907:TEU RS06400
gene id: 1505907:TEU_RS06400
uniprot id: A0A097QU60
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1505907:TEU RS04605
gene id: 1505907:TEU_RS04605
uniprot id: A0A097QT82
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.

1505907:TEU RS06140
gene id: 1505907:TEU_RS06140
uniprot id: A0A097QU05
names: Similarity
messages: Belongs to the GbsR family.

1505907:TEU RS01655
gene id: 1505907:TEU_RS01655
uniprot id: A0A097QRP5
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1505907:TEU RS00105
gene id: 1505907:TEU_RS00105
uniprot id: A0A097QQV4
names: Similarity
messages: Belongs to the UPF0047 family.

1505907:TEU RS09540
gene id: 1505907:TEU_RS09540
uniprot id: A0A097QVU4
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS04870
gene id: 1505907:TEU_RS04870
uniprot id: A0A097QTC4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1505907:TEU RS09720
gene id: 1505907:TEU_RS09720
uniprot id: A0A097QVW7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1505907:TEU RS02875
gene id: 1505907:TEU_RS02875
uniprot id: A0A097QSC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1505907:TEU RS08795
gene id: 1505907:TEU_RS08795
uniprot id: A0A097QVE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1505907:TEU RS05195
gene id: 1505907:TEU_RS05195
uniprot id: A0A097QTI2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1505907:TEU RS09740
gene id: 1505907:TEU_RS09740
uniprot id: A0A097QW08
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

1505907:TEU RS01915
gene id: 1505907:TEU_RS01915
uniprot id: A0A097QRU0
names: Similarity
messages: Belongs to the FrhG family.

1505907:TEU RS03025
gene id: 1505907:TEU_RS03025
uniprot id: A0A097QSG2
names: Similarity
messages: Belongs to the UPF0273 family.

1505907:TEU RS02540
gene id: 1505907:TEU_RS02540
uniprot id: A0A097QS55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1505907:TEU RS04340
gene id: 1505907:TEU_RS04340
uniprot id: A0A097QT35
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family.
messages: Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).

1505907:TEU RS04420
gene id: 1505907:TEU_RS04420
uniprot id: A0A097QT49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1505907:TEU RS01445
gene id: 1505907:TEU_RS01445
uniprot id: A0A097QRK9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1505907:TEU RS09825
gene id: 1505907:TEU_RS09825
uniprot id: A0A097QVZ6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Belongs to the ribosomal protein L31e family.

1505907:TEU RS09955
gene id: 1505907:TEU_RS09955
uniprot id: A0A097QW09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1505907:TEU RS05920
gene id: 1505907:TEU_RS05920
uniprot id: A0A097QTW0
names: Similarity
messages: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family.

1505907:TEU RS00365
gene id: 1505907:TEU_RS00365
uniprot id: A0A097QR19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1505907:TEU RS05000
gene id: 1505907:TEU_RS05000
uniprot id: A0A097QTH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1505907:TEU RS02165
gene id: 1505907:TEU_RS02165
uniprot id: A0A097QRY5
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C5 position of cytosine 72 in several tRNAs.

1505907:TEU RS09200
gene id: 1505907:TEU_RS09200
uniprot id: A0A097QVM9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1505907:TEU RS09900
gene id: 1505907:TEU_RS09900
uniprot id: A0A097QW12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin alpha subunit family.
messages: Belongs to the prefoldin subunit alpha family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

1505907:TEU RS09835
gene id: 1505907:TEU_RS09835
uniprot id: A0A097QVZ5
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL20 family.
messages: Part of the 50S ribosomal subunit. Binds 23S rRNA.

1505907:TEU RS07180
gene id: 1505907:TEU_RS07180
uniprot id: A0A097QUK0
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS06150
gene id: 1505907:TEU_RS06150
uniprot id: A0A097QU11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1505907:TEU RS10655
gene id: 1505907:TEU_RS10655
uniprot id: A0A097QWF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1505907:TEU RS06545
gene id: 1505907:TEU_RS06545
uniprot id: A0A097QUA4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

1505907:TEU RS05370
gene id: 1505907:TEU_RS05370
uniprot id: A0A097QTK9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1505907:TEU RS00455
gene id: 1505907:TEU_RS00455
uniprot id: A0A097QR21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1505907:TEU RS03465
gene id: 1505907:TEU_RS03465
uniprot id: A0A097QSL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1505907:TEU RS01795
gene id: 1505907:TEU_RS01795
uniprot id: A0A097QRS0
names: Similarity
messages: Belongs to the peptidase S9C family.

1505907:TEU RS07280
gene id: 1505907:TEU_RS07280
uniprot id: A0A097QUL9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1505907:TEU RS09870
gene id: 1505907:TEU_RS09870
uniprot id: A0A097QVZ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.

1505907:TEU RS00080
gene id: 1505907:TEU_RS00080
uniprot id: A0A097QQU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1505907:TEU RS10840
gene id: 1505907:TEU_RS10840
uniprot id: A0A097QWL2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carbohydrate kinase PfkC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor.
messages: Cytoplasm

1505907:TEU RS05200
gene id: 1505907:TEU_RS05200
uniprot id: A0A097QTK2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1505907:TEU RS08870
gene id: 1505907:TEU_RS08870
uniprot id: A0A097QVH4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL24 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14.

1505907:TEU RS06980
gene id: 1505907:TEU_RS06980
uniprot id: A0A097QUG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Cytoplasm
messages: Functions by promoting the formation of the first peptide bond.

1505907:TEU RS04630
gene id: 1505907:TEU_RS04630
uniprot id: A0A097QT86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm

1505907:TEU RS04730
gene id: 1505907:TEU_RS04730
uniprot id: A0A097QTB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRP4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome.

1505907:TEU RS07080
gene id: 1505907:TEU_RS07080
uniprot id: A0A097QUH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1505907:TEU RS01370
gene id: 1505907:TEU_RS01370
uniprot id: A0A097QRJ7
names: Subcellular Location Annotation
messages: Membrane

1505907:TEU RS06745
gene id: 1505907:TEU_RS06745
uniprot id: A0A097QUA7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1505907:TEU RS08245
gene id: 1505907:TEU_RS08245
uniprot id: A0A097QV55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1505907:TEU RS01230
gene id: 1505907:TEU_RS01230
uniprot id: A0A097QRH0
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1505907:TEU RS05420
gene id: 1505907:TEU_RS05420
uniprot id: A0A097QTP7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

1505907:TEU RS06785
gene id: 1505907:TEU_RS06785
uniprot id: A0A097QUD0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1505907:TEU RS06355
gene id: 1505907:TEU_RS06355
uniprot id: A0A097QU48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-alpha family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

1505907:TEU RS04950
gene id: 1505907:TEU_RS04950
uniprot id: A0A097QTE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane