1504:CP523 RS14510
gene id: 1504:CP523_RS14510
uniprot id: A0A386PJX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1504:CP523 RS07565
gene id: 1504:CP523_RS07565
uniprot id: A0A386PE49
names: Similarity
messages: Belongs to the peptidase S16 family.

1504:CP523 RS03200
gene id: 1504:CP523_RS03200
uniprot id: A0A386PG81
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1504:CP523 RS01065
gene id: 1504:CP523_RS01065
uniprot id: A0A386PCU2
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1504:CP523 RS04805
gene id: 1504:CP523_RS04805
uniprot id: A0A386PI46
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.

1504:CP523 RS12985
gene id: 1504:CP523_RS12985
uniprot id: A0A386PHI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

1504:CP523 RS06810
gene id: 1504:CP523_RS06810
uniprot id: A0A386PEF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1504:CP523 RS14515
gene id: 1504:CP523_RS14515
uniprot id: A0A386PL30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1504:CP523 RS08770
gene id: 1504:CP523_RS08770
uniprot id: A0A386PHZ6
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1504:CP523 RS07115
gene id: 1504:CP523_RS07115
uniprot id: A0A386PG71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1504:CP523 RS08495
gene id: 1504:CP523_RS08495
uniprot id: A0A386PHC0
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1504:CP523 RS01150
gene id: 1504:CP523_RS01150
uniprot id: A0A386PG55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1504:CP523 RS10750
gene id: 1504:CP523_RS10750
uniprot id: A0A386PGD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1504:CP523 RS09040
gene id: 1504:CP523_RS09040
uniprot id: A0A386PFH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1504:CP523 RS09025
gene id: 1504:CP523_RS09025
uniprot id: A0A386PGJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1504:CP523 RS08405
gene id: 1504:CP523_RS08405
uniprot id: A0A386PGW8
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

1504:CP523 RS13530
gene id: 1504:CP523_RS13530
uniprot id: A0A386PJI5
names: Similarity
messages: Belongs to the peptidase M18 family.

1504:CP523 RS14825
gene id: 1504:CP523_RS14825
uniprot id: A0A386PLF8
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

1504:CP523 RS00380
gene id: 1504:CP523_RS00380
uniprot id: A0A386PDD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1504:CP523 RS15220
gene id: 1504:CP523_RS15220
uniprot id: A0A386PJJ8
names: Similarity
messages: Belongs to the peptidase S11 family.

1504:CP523 RS03555
gene id: 1504:CP523_RS03555
uniprot id: A0A386PG06
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1504:CP523 RS10635
gene id: 1504:CP523_RS10635
uniprot id: A0A386PIV5
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS01650
gene id: 1504:CP523_RS01650
uniprot id: A0A386PD52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1504:CP523 RS02970
gene id: 1504:CP523_RS02970
uniprot id: A0A386PF47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1504:CP523 RS02055
gene id: 1504:CP523_RS02055
uniprot id: A0A386PL76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1504:CP523 RS13400
gene id: 1504:CP523_RS13400
uniprot id: A0A386PIU4
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS08960
gene id: 1504:CP523_RS08960
uniprot id: A0A386PH70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1504:CP523 RS13040
gene id: 1504:CP523_RS13040
uniprot id: A0A386PLG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1504:CP523 RS06560
gene id: 1504:CP523_RS06560
uniprot id: A0A386PDR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1504:CP523 RS09965
gene id: 1504:CP523_RS09965
uniprot id: A0A386PIK4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1504:CP523 RS14355
gene id: 1504:CP523_RS14355
uniprot id: A0A386PHF8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1504:CP523 RS08115
gene id: 1504:CP523_RS08115
uniprot id: A0A386PJL7
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1504:CP523 RS09595
gene id: 1504:CP523_RS09595
uniprot id: A0A386PF34
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1504:CP523 RS09115
gene id: 1504:CP523_RS09115
uniprot id: A0A386PET9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1504:CP523 RS02015
gene id: 1504:CP523_RS02015
uniprot id: A0A386PC28
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

1504:CP523 RS00945
gene id: 1504:CP523_RS00945
uniprot id: A0A386PDN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1504:CP523 RS15085
gene id: 1504:CP523_RS15085
uniprot id: A0A386PHR0
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1504:CP523 RS00145
gene id: 1504:CP523_RS00145
uniprot id: A0A386PD86
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1504:CP523 RS02800
gene id: 1504:CP523_RS02800
uniprot id: A0A386PDA8
names: Similarity
messages: Belongs to the UPF0473 family.

1504:CP523 RS02020
gene id: 1504:CP523_RS02020
uniprot id: A0A386PE61
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

1504:CP523 RS03450
gene id: 1504:CP523_RS03450
uniprot id: A0A386PFY4
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS07195
gene id: 1504:CP523_RS07195
uniprot id: A0A386PFP1
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1504:CP523 RS12035
gene id: 1504:CP523_RS12035
uniprot id: A0A386PK65
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

1504:CP523 RS04495
gene id: 1504:CP523_RS04495
uniprot id: A0A386PEW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Membrane

1504:CP523 RS07095
gene id: 1504:CP523_RS07095
uniprot id: A0A386PI14
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS09475
gene id: 1504:CP523_RS09475
uniprot id: A0A386PF13
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS00650
gene id: 1504:CP523_RS00650
uniprot id: A0A386PAU9
names: Similarity
messages: Belongs to the ribF family.

1504:CP523 RS13605
gene id: 1504:CP523_RS13605
uniprot id: A0A386PKZ7
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1504:CP523 RS10615
gene id: 1504:CP523_RS10615
uniprot id: A0A386PI16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1504:CP523 RS07915
gene id: 1504:CP523_RS07915
uniprot id: A0A386PH23
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1504:CP523 RS11140
gene id: 1504:CP523_RS11140
uniprot id: A0A386PHS2
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1504:CP523 RS05930
gene id: 1504:CP523_RS05930
uniprot id: A0A386PFL1
names: Similarity
messages: Belongs to the peptidase M18 family.

1504:CP523 RS09015
gene id: 1504:CP523_RS09015
uniprot id: A0A386PER9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1504:CP523 RS10940
gene id: 1504:CP523_RS10940
uniprot id: A0A386PHM2
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS00775
gene id: 1504:CP523_RS00775
uniprot id: A0A386PE05
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1504:CP523 RS07575
gene id: 1504:CP523_RS07575
uniprot id: A0A386PFU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

1504:CP523 RS10510
gene id: 1504:CP523_RS10510
uniprot id: A0A386PHZ8
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

1504:CP523 RS12465
gene id: 1504:CP523_RS12465
uniprot id: A0A386PIY3
names: Similarity
messages: Belongs to the EutP/PduV family.

1504:CP523 RS10115
gene id: 1504:CP523_RS10115
uniprot id: A0A386PF88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

1504:CP523 RS02070
gene id: 1504:CP523_RS02070
uniprot id: A0A386PC37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1504:CP523 RS00480
gene id: 1504:CP523_RS00480
uniprot id: A0A386PBA9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1504:CP523 RS14195
gene id: 1504:CP523_RS14195
uniprot id: A0A386PKY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1504:CP523 RS01230
gene id: 1504:CP523_RS01230
uniprot id: A0A386PCX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1504:CP523 RS00465
gene id: 1504:CP523_RS00465
uniprot id: A0A386PBV9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

1504:CP523 RS03215
gene id: 1504:CP523_RS03215
uniprot id: A0A386PC74
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1504:CP523 RS12155
gene id: 1504:CP523_RS12155
uniprot id: A0A386PIU3
names: Similarity
messages: Belongs to the UPF0473 family.

1504:CP523 RS13600
gene id: 1504:CP523_RS13600
uniprot id: A0A386PH07
names: Similarity
messages: Belongs to the pyruvate kinase family.

1504:CP523 RS15655
gene id: 1504:CP523_RS15655
uniprot id: A0A386PKE2
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS06085
gene id: 1504:CP523_RS06085
uniprot id: A0A386PFN5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1504:CP523 RS12025
gene id: 1504:CP523_RS12025
uniprot id: A0A386PH14
names: Function
names: Similarity
messages: Belongs to the V-ATPase F subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1504:CP523 RS02810
gene id: 1504:CP523_RS02810
uniprot id: A0A386PH05
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1504:CP523 RS01235
gene id: 1504:CP523_RS01235
uniprot id: A0A386PB77
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1504:CP523 RS12450
gene id: 1504:CP523_RS12450
uniprot id: A0A386PJ15
names: Function
names: PTM
names: Similarity
messages: Belongs to the glycyl radical enzyme (GRE) family. CutC subfamily.
messages: Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde.
messages: Requires the activating protein CutD to generate the key active site glycyl radical on Gly-821 that is involved in catalysis.

1504:CP523 RS11875
gene id: 1504:CP523_RS11875
uniprot id: A0A386PK44
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1504:CP523 RS09920
gene id: 1504:CP523_RS09920
uniprot id: A0A386PKC2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1504:CP523 RS00500
gene id: 1504:CP523_RS00500
uniprot id: A0A386PCI9
names: Similarity
messages: Belongs to the peptidase S8 family.

1504:CP523 RS02725
gene id: 1504:CP523_RS02725
uniprot id: A0A386PFZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

1504:CP523 RS08325
gene id: 1504:CP523_RS08325
uniprot id: A0A386PHR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

1504:CP523 RS08845
gene id: 1504:CP523_RS08845
uniprot id: A0A386PEP9
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS05915
gene id: 1504:CP523_RS05915
uniprot id: A0A386PG88
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS14880
gene id: 1504:CP523_RS14880
uniprot id: A0A386PHM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1504:CP523 RS08175
gene id: 1504:CP523_RS08175
uniprot id: A0A386PF20
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1504:CP523 RS06915
gene id: 1504:CP523_RS06915
uniprot id: A0A386PGN6
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1504:CP523 RS14400
gene id: 1504:CP523_RS14400
uniprot id: A0A386PJW0
names: Caution
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1504:CP523 RS10890
gene id: 1504:CP523_RS10890
uniprot id: A0A386PHL1
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1504:CP523 RS10670
gene id: 1504:CP523_RS10670
uniprot id: A0A386PI29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1504:CP523 RS02235
gene id: 1504:CP523_RS02235
uniprot id: A0A386PFR2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1504:CP523 RS15190
gene id: 1504:CP523_RS15190
uniprot id: A0A386PKQ8
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1504:CP523 RS12765
gene id: 1504:CP523_RS12765
uniprot id: A0A386PLD9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1504:CP523 RS06905
gene id: 1504:CP523_RS06905
uniprot id: A0A386PJ62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1504:CP523 RS07605
gene id: 1504:CP523_RS07605
uniprot id: A0A386PE59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1504:CP523 RS15120
gene id: 1504:CP523_RS15120
uniprot id: A0A386PK70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS05435
gene id: 1504:CP523_RS05435
uniprot id: A0A386PHB2
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1504:CP523 RS03545
gene id: 1504:CP523_RS03545
uniprot id: A0A386PEC4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1504:CP523 RS00820
gene id: 1504:CP523_RS00820
uniprot id: A0A386PEK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1504:CP523 RS02780
gene id: 1504:CP523_RS02780
uniprot id: A0A386PBZ5
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1504:CP523 RS15195
gene id: 1504:CP523_RS15195
uniprot id: A0A386PHV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

1504:CP523 RS13425
gene id: 1504:CP523_RS13425
uniprot id: A0A386PKP6
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1504:CP523 RS11060
gene id: 1504:CP523_RS11060
uniprot id: A0A386PIJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1504:CP523 RS01770
gene id: 1504:CP523_RS01770
uniprot id: A0A386PF32
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1504:CP523 RS12725
gene id: 1504:CP523_RS12725
uniprot id: A0A386PJ58
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1504:CP523 RS06870
gene id: 1504:CP523_RS06870
uniprot id: A0A386PHW3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS12020
gene id: 1504:CP523_RS12020
uniprot id: A0A386PL53
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.

1504:CP523 RS12990
gene id: 1504:CP523_RS12990
uniprot id: A0A386PJ99
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

1504:CP523 RS03850
gene id: 1504:CP523_RS03850
uniprot id: A0A386PF59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1504:CP523 RS07175
gene id: 1504:CP523_RS07175
uniprot id: A0A386PE03
names: Similarity
messages: Belongs to the DEAD box helicase family.

1504:CP523 RS02325
gene id: 1504:CP523_RS02325
uniprot id: A0A386PGR8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1504:CP523 RS12295
gene id: 1504:CP523_RS12295
uniprot id: A0A386PIZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

1504:CP523 RS02290
gene id: 1504:CP523_RS02290
uniprot id: A0A386PBQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1504:CP523 RS00940
gene id: 1504:CP523_RS00940
uniprot id: A0A386PBJ7
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1504:CP523 RS12955
gene id: 1504:CP523_RS12955
uniprot id: A0A386PJ48
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1504:CP523 RS11885
gene id: 1504:CP523_RS11885
uniprot id: A0A386PIQ7
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1504:CP523 RS00720
gene id: 1504:CP523_RS00720
uniprot id: A0A386PC13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1504:CP523 RS12270
gene id: 1504:CP523_RS12270
uniprot id: A0A386PKF0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1504:CP523 RS10715
gene id: 1504:CP523_RS10715
uniprot id: A0A386PFK4
names: Similarity
messages: Belongs to the peptidase S11 family.

1504:CP523 RS02190
gene id: 1504:CP523_RS02190
uniprot id: A0A386PBP0
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1504:CP523 RS00710
gene id: 1504:CP523_RS00710
uniprot id: A0A386PAX0
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS13025
gene id: 1504:CP523_RS13025
uniprot id: A0A386PJ18
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1504:CP523 RS08520
gene id: 1504:CP523_RS08520
uniprot id: A0A386PEJ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1504:CP523 RS02320
gene id: 1504:CP523_RS02320
uniprot id: A0A386PES5
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

1504:CP523 RS11020
gene id: 1504:CP523_RS11020
uniprot id: A0A386PFR7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1504:CP523 RS14225
gene id: 1504:CP523_RS14225
uniprot id: A0A386PKK4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1504:CP523 RS03965
gene id: 1504:CP523_RS03965
uniprot id: A0A386PCJ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1504:CP523 RS00925
gene id: 1504:CP523_RS00925
uniprot id: A0A386PCB3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1504:CP523 RS08995
gene id: 1504:CP523_RS08995
uniprot id: A0A386PHK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1504:CP523 RS12220
gene id: 1504:CP523_RS12220
uniprot id: A0A386PKE7
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1504:CP523 RS14745
gene id: 1504:CP523_RS14745
uniprot id: A0A386PL59
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

1504:CP523 RS01780
gene id: 1504:CP523_RS01780
uniprot id: A0A386PEI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1504:CP523 RS07275
gene id: 1504:CP523_RS07275
uniprot id: A0A386PH93
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

1504:CP523 RS00055
gene id: 1504:CP523_RS00055
uniprot id: A0A386PAK1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1504:CP523 RS01375
gene id: 1504:CP523_RS01375
uniprot id: A0A386PI72
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS02270
gene id: 1504:CP523_RS02270
uniprot id: A0A386PGR2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1504:CP523 RS02145
gene id: 1504:CP523_RS02145
uniprot id: A0A386PDE0
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1504:CP523 RS09235
gene id: 1504:CP523_RS09235
uniprot id: A0A386PK40
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1504:CP523 RS01020
gene id: 1504:CP523_RS01020
uniprot id: A0A386PB40
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1504:CP523 RS14030
gene id: 1504:CP523_RS14030
uniprot id: A0A386PI20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1504:CP523 RS00610
gene id: 1504:CP523_RS00610
uniprot id: A0A386PEH2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1504:CP523 RS08395
gene id: 1504:CP523_RS08395
uniprot id: A0A386PIJ0
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

1504:CP523 RS03045
gene id: 1504:CP523_RS03045
uniprot id: A0A386PG54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1504:CP523 RS06900
gene id: 1504:CP523_RS06900
uniprot id: A0A386PH35
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

1504:CP523 RS04000
gene id: 1504:CP523_RS04000
uniprot id: A0A386PD18
names: Similarity
messages: Belongs to the sigma-54 factor family.

1504:CP523 RS01440
gene id: 1504:CP523_RS01440
uniprot id: A0A386PBB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1504:CP523 RS09455
gene id: 1504:CP523_RS09455
uniprot id: A0A386PK76
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1504:CP523 RS14265
gene id: 1504:CP523_RS14265
uniprot id: A0A386PL87
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1504:CP523 RS01790
gene id: 1504:CP523_RS01790
uniprot id: A0A386PBZ2
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1504:CP523 RS02650
gene id: 1504:CP523_RS02650
uniprot id: A0A386PEY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1504:CP523 RS07950
gene id: 1504:CP523_RS07950
uniprot id: A0A386PIC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1504:CP523 RS13650
gene id: 1504:CP523_RS13650
uniprot id: A0A386PJG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

1504:CP523 RS14765
gene id: 1504:CP523_RS14765
uniprot id: A0A386PLF4
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS00815
gene id: 1504:CP523_RS00815
uniprot id: A0A386PB01
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

1504:CP523 RS09585
gene id: 1504:CP523_RS09585
uniprot id: A0A386PHV4
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1504:CP523 RS03165
gene id: 1504:CP523_RS03165
uniprot id: A0A386PC64
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1504:CP523 RS13755
gene id: 1504:CP523_RS13755
uniprot id: A0A386PJH7
names: Similarity
messages: Belongs to the peptidase S11 family.

1504:CP523 RS08900
gene id: 1504:CP523_RS08900
uniprot id: A0A386PEQ9
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival.

1504:CP523 RS05220
gene id: 1504:CP523_RS05220
uniprot id: A0A386PF96
names: Similarity
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.

1504:CP523 RS09100
gene id: 1504:CP523_RS09100
uniprot id: A0A386PIS4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

1504:CP523 RS15690
gene id: 1504:CP523_RS15690
uniprot id: A0A386PLR9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1504:CP523 RS12030
gene id: 1504:CP523_RS12030
uniprot id: A0A386PIW6
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

1504:CP523 RS11780
gene id: 1504:CP523_RS11780
uniprot id: A0A386PG50
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

1504:CP523 RS02675
gene id: 1504:CP523_RS02675
uniprot id: A0A386PBX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1504:CP523 RS09145
gene id: 1504:CP523_RS09145
uniprot id: A0A386PHN0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1504:CP523 RS04095
gene id: 1504:CP523_RS04095
uniprot id: A0A386PHQ9
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1504:CP523 RS10680
gene id: 1504:CP523_RS10680
uniprot id: A0A386PJN3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1504:CP523 RS05800
gene id: 1504:CP523_RS05800
uniprot id: A0A386PIS2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1504:CP523 RS14555
gene id: 1504:CP523_RS14555
uniprot id: A0A386PKP9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS07695
gene id: 1504:CP523_RS07695
uniprot id: A0A386PJG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1504:CP523 RS00840
gene id: 1504:CP523_RS00840
uniprot id: A0A386PBH3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1504:CP523 RS03190
gene id: 1504:CP523_RS03190
uniprot id: A0A386PCM9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1504:CP523 RS13965
gene id: 1504:CP523_RS13965
uniprot id: A0A386PKG5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1504:CP523 RS00700
gene id: 1504:CP523_RS00700
uniprot id: A0A386PAW4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1504:CP523 RS03635
gene id: 1504:CP523_RS03635
uniprot id: A0A386PF15
names: Similarity
messages: Belongs to the peptidase S8 family.

1504:CP523 RS05925
gene id: 1504:CP523_RS05925
uniprot id: A0A386PDF9
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS08885
gene id: 1504:CP523_RS08885
uniprot id: A0A386PHH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

1504:CP523 RS07595
gene id: 1504:CP523_RS07595
uniprot id: A0A386PGY1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1504:CP523 RS02210
gene id: 1504:CP523_RS02210
uniprot id: A0A386PD02
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1504:CP523 RS01485
gene id: 1504:CP523_RS01485
uniprot id: A0A386PD20
names: Similarity
messages: Belongs to the CobH/CbiC family.

1504:CP523 RS09250
gene id: 1504:CP523_RS09250
uniprot id: A0A386PIU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1504:CP523 RS01850
gene id: 1504:CP523_RS01850
uniprot id: A0A386PE35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

1504:CP523 RS10320
gene id: 1504:CP523_RS10320
uniprot id: A0A386PG48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1504:CP523 RS12835
gene id: 1504:CP523_RS12835
uniprot id: A0A386PKG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0397 family.
messages: Cell membrane

1504:CP523 RS02550
gene id: 1504:CP523_RS02550
uniprot id: A0A386PGV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1504:CP523 RS00765
gene id: 1504:CP523_RS00765
uniprot id: A0A386PEJ8
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1504:CP523 RS06755
gene id: 1504:CP523_RS06755
uniprot id: A0A386PDU3
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS09300
gene id: 1504:CP523_RS09300
uniprot id: A0A386PIV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1504:CP523 RS14315
gene id: 1504:CP523_RS14315
uniprot id: A0A386PL96
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1504:CP523 RS00600
gene id: 1504:CP523_RS00600
uniprot id: A0A386PCK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1504:CP523 RS13050
gene id: 1504:CP523_RS13050
uniprot id: A0A386PJA8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1504:CP523 RS01260
gene id: 1504:CP523_RS01260
uniprot id: A0A386PBQ6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1504:CP523 RS03320
gene id: 1504:CP523_RS03320
uniprot id: A0A386PC90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1504:CP523 RS01845
gene id: 1504:CP523_RS01845
uniprot id: A0A386PKJ2
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1504:CP523 RS09170
gene id: 1504:CP523_RS09170
uniprot id: A0A386PJ05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1504:CP523 RS14570
gene id: 1504:CP523_RS14570
uniprot id: A0A386PIB6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1504:CP523 RS12195
gene id: 1504:CP523_RS12195
uniprot id: A0A386PIY5
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS02635
gene id: 1504:CP523_RS02635
uniprot id: A0A386PBW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1504:CP523 RS08510
gene id: 1504:CP523_RS08510
uniprot id: A0A386PEK1
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

1504:CP523 RS15410
gene id: 1504:CP523_RS15410
uniprot id: A0A386PLF2
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS06520
gene id: 1504:CP523_RS06520
uniprot id: A0A386PDQ5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1504:CP523 RS02815
gene id: 1504:CP523_RS02815
uniprot id: A0A386PCG7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS07155
gene id: 1504:CP523_RS07155
uniprot id: A0A386PEK5
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1504:CP523 RS03740
gene id: 1504:CP523_RS03740
uniprot id: A0A386PF37
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS09060
gene id: 1504:CP523_RS09060
uniprot id: A0A386PH90
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1504:CP523 RS10605
gene id: 1504:CP523_RS10605
uniprot id: A0A386PJH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1504:CP523 RS00850
gene id: 1504:CP523_RS00850
uniprot id: A0A386PF36
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1504:CP523 RS15520
gene id: 1504:CP523_RS15520
uniprot id: A0A386PKA9
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS07075
gene id: 1504:CP523_RS07075
uniprot id: A0A386PH61
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS06365
gene id: 1504:CP523_RS06365
uniprot id: A0A386PDN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

1504:CP523 RS12930
gene id: 1504:CP523_RS12930
uniprot id: A0A386PLF5
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1504:CP523 RS10215
gene id: 1504:CP523_RS10215
uniprot id: A0A386PFB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1504:CP523 RS12010
gene id: 1504:CP523_RS12010
uniprot id: A0A386PI99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane

1504:CP523 RS00640
gene id: 1504:CP523_RS00640
uniprot id: A0A386PDH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1504:CP523 RS09085
gene id: 1504:CP523_RS09085
uniprot id: A0A386PK14
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1504:CP523 RS00440
gene id: 1504:CP523_RS00440
uniprot id: A0A386PAR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1504:CP523 RS07980
gene id: 1504:CP523_RS07980
uniprot id: A0A386PH31
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type II sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

1504:CP523 RS12045
gene id: 1504:CP523_RS12045
uniprot id: A0A386PIS8
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS14935
gene id: 1504:CP523_RS14935
uniprot id: A0A386PLH0
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1504:CP523 RS03510
gene id: 1504:CP523_RS03510
uniprot id: A0A386PDQ3
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS00895
gene id: 1504:CP523_RS00895
uniprot id: A0A386PDM7
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1504:CP523 RS14475
gene id: 1504:CP523_RS14475
uniprot id: A0A386PHF5
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

1504:CP523 RS15770
gene id: 1504:CP523_RS15770
uniprot id: A0A386PLJ6
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS01925
gene id: 1504:CP523_RS01925
uniprot id: A0A386PDA2
names: Similarity
messages: Belongs to the CvfB family.

1504:CP523 RS07670
gene id: 1504:CP523_RS07670
uniprot id: A0A386PE71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

1504:CP523 RS00575
gene id: 1504:CP523_RS00575
uniprot id: A0A386PFV3
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1504:CP523 RS08275
gene id: 1504:CP523_RS08275
uniprot id: A0A386PHQ5
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS10200
gene id: 1504:CP523_RS10200
uniprot id: A0A386PJB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1504:CP523 RS09590
gene id: 1504:CP523_RS09590
uniprot id: A0A386PJ32
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1504:CP523 RS08490
gene id: 1504:CP523_RS08490
uniprot id: A0A386PF76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1504:CP523 RS03455
gene id: 1504:CP523_RS03455
uniprot id: A0A386PDP2
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS02380
gene id: 1504:CP523_RS02380
uniprot id: A0A386PET5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1504:CP523 RS09580
gene id: 1504:CP523_RS09580
uniprot id: A0A386PFS4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1504:CP523 RS03750
gene id: 1504:CP523_RS03750
uniprot id: A0A386PCF7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1504:CP523 RS09245
gene id: 1504:CP523_RS09245
uniprot id: A0A386PHQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1504:CP523 RS10630
gene id: 1504:CP523_RS10630
uniprot id: A0A386PHF6
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1504:CP523 RS01110
gene id: 1504:CP523_RS01110
uniprot id: A0A386PDR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1504:CP523 RS06950
gene id: 1504:CP523_RS06950
uniprot id: A0A386PDW0
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS06430
gene id: 1504:CP523_RS06430
uniprot id: A0A386PGW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1504:CP523 RS09405
gene id: 1504:CP523_RS09405
uniprot id: A0A386PIW7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

1504:CP523 RS02605
gene id: 1504:CP523_RS02605
uniprot id: A0A386PGW6
names: Subcellular Location Annotation
messages: Cytoplasm

1504:CP523 RS09070
gene id: 1504:CP523_RS09070
uniprot id: A0A386PIY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1504:CP523 RS09205
gene id: 1504:CP523_RS09205
uniprot id: A0A386PEW7
names: Similarity
messages: Belongs to the class-I fumarase family.

1504:CP523 RS09570
gene id: 1504:CP523_RS09570
uniprot id: A0A386PIG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1504:CP523 RS09670
gene id: 1504:CP523_RS09670
uniprot id: A0A386PGZ1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1504:CP523 RS08260
gene id: 1504:CP523_RS08260
uniprot id: A0A386PEE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1504:CP523 RS06495
gene id: 1504:CP523_RS06495
uniprot id: A0A386PEA2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1504:CP523 RS00910
gene id: 1504:CP523_RS00910
uniprot id: A0A386PCR4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1504:CP523 RS10420
gene id: 1504:CP523_RS10420
uniprot id: A0A386PG68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

1504:CP523 RS06315
gene id: 1504:CP523_RS06315
uniprot id: A0A386PGU2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1504:CP523 RS12760
gene id: 1504:CP523_RS12760
uniprot id: A0A386PJT9
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1504:CP523 RS06515
gene id: 1504:CP523_RS06515
uniprot id: A0A386PFY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1504:CP523 RS07545
gene id: 1504:CP523_RS07545
uniprot id: A0A386PGX1
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1504:CP523 RS08480
gene id: 1504:CP523_RS08480
uniprot id: A0A386PHV0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1504:CP523 RS12515
gene id: 1504:CP523_RS12515
uniprot id: A0A386PIY7
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1504:CP523 RS02705
gene id: 1504:CP523_RS02705
uniprot id: A0A386PGY6
names: Similarity
messages: Belongs to the bacterial flagellin family.

1504:CP523 RS09140
gene id: 1504:CP523_RS09140
uniprot id: A0A386PFJ9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1504:CP523 RS00495
gene id: 1504:CP523_RS00495
uniprot id: A0A386PAS1
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1504:CP523 RS11880
gene id: 1504:CP523_RS11880
uniprot id: A0A386PG84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1504:CP523 RS14600
gene id: 1504:CP523_RS14600
uniprot id: A0A386PKY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1504:CP523 RS03310
gene id: 1504:CP523_RS03310
uniprot id: A0A386PC78
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1504:CP523 RS02625
gene id: 1504:CP523_RS02625
uniprot id: A0A386PBW6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1504:CP523 RS03945
gene id: 1504:CP523_RS03945
uniprot id: A0A386PHM9
names: Subcellular Location Annotation
messages: Cytoplasm

1504:CP523 RS00905
gene id: 1504:CP523_RS00905
uniprot id: A0A386PB17
names: Similarity
messages: Belongs to the asp23 family.

1504:CP523 RS14610
gene id: 1504:CP523_RS14610
uniprot id: A0A386PLC7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1504:CP523 RS10785
gene id: 1504:CP523_RS10785
uniprot id: A0A386PJQ0
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

1504:CP523 RS11900
gene id: 1504:CP523_RS11900
uniprot id: A0A386PK89
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1504:CP523 RS10625
gene id: 1504:CP523_RS10625
uniprot id: A0A386PJM5
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

1504:CP523 RS15755
gene id: 1504:CP523_RS15755
uniprot id: A0A386PM85
names: Similarity
messages: Belongs to the peptidase S24 family.

1504:CP523 RS11425
gene id: 1504:CP523_RS11425
uniprot id: A0A386PIN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1504:CP523 RS01090
gene id: 1504:CP523_RS01090
uniprot id: A0A386PCE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1504:CP523 RS03820
gene id: 1504:CP523_RS03820
uniprot id: A0A386PCH4
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1504:CP523 RS03830
gene id: 1504:CP523_RS03830
uniprot id: A0A386PDW5
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1504:CP523 RS11635
gene id: 1504:CP523_RS11635
uniprot id: A0A386PK16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1504:CP523 RS09770
gene id: 1504:CP523_RS09770
uniprot id: A0A386PF50
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1504:CP523 RS06345
gene id: 1504:CP523_RS06345
uniprot id: A0A386PI87
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1504:CP523 RS13395
gene id: 1504:CP523_RS13395
uniprot id: A0A386PKW7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS13560
gene id: 1504:CP523_RS13560
uniprot id: A0A386PIW5
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1504:CP523 RS00490
gene id: 1504:CP523_RS00490
uniprot id: A0A386PEX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1504:CP523 RS02175
gene id: 1504:CP523_RS02175
uniprot id: A0A386PC56
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1504:CP523 RS10295
gene id: 1504:CP523_RS10295
uniprot id: A0A386PFC1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1504:CP523 RS06575
gene id: 1504:CP523_RS06575
uniprot id: A0A386PHS4
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS14480
gene id: 1504:CP523_RS14480
uniprot id: A0A386PLB4
names: Similarity
messages: Belongs to the DEAD box helicase family.

1504:CP523 RS04035
gene id: 1504:CP523_RS04035
uniprot id: A0A386PE08
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1504:CP523 RS11545
gene id: 1504:CP523_RS11545
uniprot id: A0A386PIL1
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1504:CP523 RS11740
gene id: 1504:CP523_RS11740
uniprot id: A0A386PIT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1504:CP523 RS01220
gene id: 1504:CP523_RS01220
uniprot id: A0A386PF98
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1504:CP523 RS12005
gene id: 1504:CP523_RS12005
uniprot id: A0A386PKA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

1504:CP523 RS14930
gene id: 1504:CP523_RS14930
uniprot id: A0A386PHN1
names: Similarity
messages: Belongs to the UPF0749 family.

1504:CP523 RS04975
gene id: 1504:CP523_RS04975
uniprot id: A0A386PFS8
names: Similarity
messages: Belongs to the CpsD/CapB family.

1504:CP523 RS10305
gene id: 1504:CP523_RS10305
uniprot id: A0A386PH85
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1504:CP523 RS11345
gene id: 1504:CP523_RS11345
uniprot id: A0A386PFX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1504:CP523 RS08350
gene id: 1504:CP523_RS08350
uniprot id: A0A386PEH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1504:CP523 RS14560
gene id: 1504:CP523_RS14560
uniprot id: A0A386PLX4
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

1504:CP523 RS02050
gene id: 1504:CP523_RS02050
uniprot id: A0A386PCW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1504:CP523 RS02515
gene id: 1504:CP523_RS02515
uniprot id: A0A386PFV4
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1504:CP523 RS14840
gene id: 1504:CP523_RS14840
uniprot id: A0A386PK36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1504:CP523 RS01835
gene id: 1504:CP523_RS01835
uniprot id: A0A386PGI3
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

1504:CP523 RS10170
gene id: 1504:CP523_RS10170
uniprot id: A0A386PJE7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1504:CP523 RS12900
gene id: 1504:CP523_RS12900
uniprot id: A0A386PJ38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.
messages: Homotetramer.

1504:CP523 RS01915
gene id: 1504:CP523_RS01915
uniprot id: A0A386PI49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1504:CP523 RS02095
gene id: 1504:CP523_RS02095
uniprot id: A0A386PBM6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1504:CP523 RS08965
gene id: 1504:CP523_RS08965
uniprot id: A0A386PER1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1504:CP523 RS02905
gene id: 1504:CP523_RS02905
uniprot id: A0A386PFP0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1504:CP523 RS11815
gene id: 1504:CP523_RS11815
uniprot id: A0A386PGY2
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS15090
gene id: 1504:CP523_RS15090
uniprot id: A0A386PLJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1504:CP523 RS14140
gene id: 1504:CP523_RS14140
uniprot id: A0A386PJS0
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1504:CP523 RS00985
gene id: 1504:CP523_RS00985
uniprot id: A0A386PE36
names: Similarity
messages: Belongs to the RemA family.

1504:CP523 RS03385
gene id: 1504:CP523_RS03385
uniprot id: A0A386PC99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1504:CP523 RS10735
gene id: 1504:CP523_RS10735
uniprot id: A0A386PHH6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1504:CP523 RS12660
gene id: 1504:CP523_RS12660
uniprot id: A0A386PLC6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1504:CP523 RS12810
gene id: 1504:CP523_RS12810
uniprot id: A0A386PJU6
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1504:CP523 RS14605
gene id: 1504:CP523_RS14605
uniprot id: A0A386PHG9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1504:CP523 RS05935
gene id: 1504:CP523_RS05935
uniprot id: A0A386PDG3
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS02720
gene id: 1504:CP523_RS02720
uniprot id: A0A386PEJ1
names: Similarity
messages: Belongs to the FlgM family.

1504:CP523 RS00625
gene id: 1504:CP523_RS00625
uniprot id: A0A386PDY0
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1504:CP523 RS02910
gene id: 1504:CP523_RS02910
uniprot id: A0A386PDC8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1504:CP523 RS00595
gene id: 1504:CP523_RS00595
uniprot id: A0A386PAT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

1504:CP523 RS06090
gene id: 1504:CP523_RS06090
uniprot id: A0A386PDI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1504:CP523 RS00565
gene id: 1504:CP523_RS00565
uniprot id: A0A386PBX8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1504:CP523 RS13045
gene id: 1504:CP523_RS13045
uniprot id: A0A386PHJ4
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS08040
gene id: 1504:CP523_RS08040
uniprot id: A0A386PEB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1504:CP523 RS11960
gene id: 1504:CP523_RS11960
uniprot id: A0A386PJG4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1504:CP523 RS01460
gene id: 1504:CP523_RS01460
uniprot id: A0A386PGB2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1504:CP523 RS09735
gene id: 1504:CP523_RS09735
uniprot id: A0A386PKB5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1504:CP523 RS07705
gene id: 1504:CP523_RS07705
uniprot id: A0A386PH02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1504:CP523 RS06025
gene id: 1504:CP523_RS06025
uniprot id: A0A386PHK3
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1504:CP523 RS00790
gene id: 1504:CP523_RS00790
uniprot id: A0A386PDK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1504:CP523 RS14240
gene id: 1504:CP523_RS14240
uniprot id: A0A386PJT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1504:CP523 RS15155
gene id: 1504:CP523_RS15155
uniprot id: A0A386PJJ2
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1504:CP523 RS03780
gene id: 1504:CP523_RS03780
uniprot id: A0A386PFJ5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1504:CP523 RS00040
gene id: 1504:CP523_RS00040
uniprot id: A0A386PB23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers).

1504:CP523 RS06370
gene id: 1504:CP523_RS06370
uniprot id: A0A386PHN5
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1504:CP523 RS11015
gene id: 1504:CP523_RS11015
uniprot id: A0A386PJQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1504:CP523 RS01160
gene id: 1504:CP523_RS01160
uniprot id: A0A386PDS1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1504:CP523 RS11320
gene id: 1504:CP523_RS11320
uniprot id: A0A386PGP7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1504:CP523 RS00740
gene id: 1504:CP523_RS00740
uniprot id: A0A386PDJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1504:CP523 RS04985
gene id: 1504:CP523_RS04985
uniprot id: A0A386PD08
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1504:CP523 RS15100
gene id: 1504:CP523_RS15100
uniprot id: A0A386PKW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1504:CP523 RS00825
gene id: 1504:CP523_RS00825
uniprot id: A0A386PC93
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1504:CP523 RS05110
gene id: 1504:CP523_RS05110
uniprot id: A0A386PF77
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1504:CP523 RS09030
gene id: 1504:CP523_RS09030
uniprot id: A0A386PI52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1504:CP523 RS03670
gene id: 1504:CP523_RS03670
uniprot id: A0A386PDT3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1504:CP523 RS10155
gene id: 1504:CP523_RS10155
uniprot id: A0A386PFB2
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1504:CP523 RS11925
gene id: 1504:CP523_RS11925
uniprot id: A0A386PIV2
names: Similarity
messages: Belongs to the Fur family.

1504:CP523 RS00800
gene id: 1504:CP523_RS00800
uniprot id: A0A386PM98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1504:CP523 RS04015
gene id: 1504:CP523_RS04015
uniprot id: A0A386PCK2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS02640
gene id: 1504:CP523_RS02640
uniprot id: A0A386PFJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1504:CP523 RS02370
gene id: 1504:CP523_RS02370
uniprot id: A0A386PKJ1
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

1504:CP523 RS11945
gene id: 1504:CP523_RS11945
uniprot id: A0A386PG74
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1504:CP523 RS10895
gene id: 1504:CP523_RS10895
uniprot id: A0A386PIZ2
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1504:CP523 RS10110
gene id: 1504:CP523_RS10110
uniprot id: A0A386PHR9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS11725
gene id: 1504:CP523_RS11725
uniprot id: A0A386PJD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1504:CP523 RS08745
gene id: 1504:CP523_RS08745
uniprot id: A0A386PEM9
names: Similarity
messages: Belongs to the peptidase S66 family.

1504:CP523 RS01555
gene id: 1504:CP523_RS01555
uniprot id: A0A386PEE4
names: Similarity
messages: Belongs to the peptidase S66 family.

1504:CP523 RS14750
gene id: 1504:CP523_RS14750
uniprot id: A0A386PHM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3.A.1.2.3) family.
messages: Cell membrane
messages: Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system.
messages: The complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

1504:CP523 RS00685
gene id: 1504:CP523_RS00685
uniprot id: A0A386PBE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1504:CP523 RS08990
gene id: 1504:CP523_RS08990
uniprot id: A0A386PFF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1504:CP523 RS08920
gene id: 1504:CP523_RS08920
uniprot id: A0A386PIR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1504:CP523 RS11965
gene id: 1504:CP523_RS11965
uniprot id: A0A386PL46
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS06195
gene id: 1504:CP523_RS06195
uniprot id: A0A386PDK5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1504:CP523 RS06420
gene id: 1504:CP523_RS06420
uniprot id: A0A386PHP8
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1504:CP523 RS11465
gene id: 1504:CP523_RS11465
uniprot id: A0A386PJ86
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS13990
gene id: 1504:CP523_RS13990
uniprot id: A0A386PH88
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

1504:CP523 RS06585
gene id: 1504:CP523_RS06585
uniprot id: A0A386PGZ2
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS13800
gene id: 1504:CP523_RS13800
uniprot id: A0A386PH57
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS14940
gene id: 1504:CP523_RS14940
uniprot id: A0A386PJG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1504:CP523 RS05215
gene id: 1504:CP523_RS05215
uniprot id: A0A386PD46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1504:CP523 RS14165
gene id: 1504:CP523_RS14165
uniprot id: A0A386PL69
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS00960
gene id: 1504:CP523_RS00960
uniprot id: A0A386PCS4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1504:CP523 RS13795
gene id: 1504:CP523_RS13795
uniprot id: A0A386PKU2
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1504:CP523 RS02535
gene id: 1504:CP523_RS02535
uniprot id: A0A386PFH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1504:CP523 RS13735
gene id: 1504:CP523_RS13735
uniprot id: A0A386PHX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1504:CP523 RS03995
gene id: 1504:CP523_RS03995
uniprot id: A0A386PHN7
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1504:CP523 RS01505
gene id: 1504:CP523_RS01505
uniprot id: A0A386PED5
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1504:CP523 RS00805
gene id: 1504:CP523_RS00805
uniprot id: A0A386PB04
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1504:CP523 RS14290
gene id: 1504:CP523_RS14290
uniprot id: A0A386PJU4
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1504:CP523 RS08640
gene id: 1504:CP523_RS08640
uniprot id: A0A386PIL4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1504:CP523 RS15110
gene id: 1504:CP523_RS15110
uniprot id: A0A386PM29
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1504:CP523 RS11970
gene id: 1504:CP523_RS11970
uniprot id: A0A386PH04
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS13685
gene id: 1504:CP523_RS13685
uniprot id: A0A386PHW7
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS09995
gene id: 1504:CP523_RS09995
uniprot id: A0A386PKQ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1504:CP523 RS08265
gene id: 1504:CP523_RS08265
uniprot id: A0A386PII1
names: Similarity
messages: Belongs to the UPF0735 family.

1504:CP523 RS02570
gene id: 1504:CP523_RS02570
uniprot id: A0A386PFW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1504:CP523 RS01205
gene id: 1504:CP523_RS01205
uniprot id: A0A386PG64
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

1504:CP523 RS15180
gene id: 1504:CP523_RS15180
uniprot id: A0A386PJ31
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1504:CP523 RS04835
gene id: 1504:CP523_RS04835
uniprot id: A0A386PCY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1504:CP523 RS06460
gene id: 1504:CP523_RS06460
uniprot id: A0A386PFX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1504:CP523 RS08255
gene id: 1504:CP523_RS08255
uniprot id: A0A386PGT1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

1504:CP523 RS03605
gene id: 1504:CP523_RS03605
uniprot id: A0A386PG18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1504:CP523 RS11570
gene id: 1504:CP523_RS11570
uniprot id: A0A386PL01
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1504:CP523 RS12275
gene id: 1504:CP523_RS12275
uniprot id: A0A386PIE5
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1504:CP523 RS15500
gene id: 1504:CP523_RS15500
uniprot id: A0A386PIR0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1504:CP523 RS00785
gene id: 1504:CP523_RS00785
uniprot id: A0A386PBG3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1504:CP523 RS12750
gene id: 1504:CP523_RS12750
uniprot id: A0A386PKN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1504:CP523 RS02765
gene id: 1504:CP523_RS02765
uniprot id: A0A386PCF8
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1504:CP523 RS09935
gene id: 1504:CP523_RS09935
uniprot id: A0A386PJ67
names: Similarity
messages: Belongs to the peptidase U62 family.

1504:CP523 RS10210
gene id: 1504:CP523_RS10210
uniprot id: A0A386PHT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1504:CP523 RS02375
gene id: 1504:CP523_RS02375
uniprot id: A0A386PD33
names: Similarity
messages: Belongs to the peptidase S16 family.

1504:CP523 RS09090
gene id: 1504:CP523_RS09090
uniprot id: A0A386PFI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1504:CP523 RS13460
gene id: 1504:CP523_RS13460
uniprot id: A0A386PLL3
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

1504:CP523 RS03050
gene id: 1504:CP523_RS03050
uniprot id: A0A386PC39
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1504:CP523 RS08225
gene id: 1504:CP523_RS08225
uniprot id: A0A386PHP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1504:CP523 RS10885
gene id: 1504:CP523_RS10885
uniprot id: A0A386PJR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1504:CP523 RS15185
gene id: 1504:CP523_RS15185
uniprot id: A0A386PLC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

1504:CP523 RS14310
gene id: 1504:CP523_RS14310
uniprot id: A0A386PHC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1504:CP523 RS09765
gene id: 1504:CP523_RS09765
uniprot id: A0A386PHM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1504:CP523 RS01595
gene id: 1504:CP523_RS01595
uniprot id: A0A386PF04
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1504:CP523 RS06485
gene id: 1504:CP523_RS06485
uniprot id: A0A386PGX4
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS03920
gene id: 1504:CP523_RS03920
uniprot id: A0A386PEK0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1504:CP523 RS08805
gene id: 1504:CP523_RS08805
uniprot id: A0A386PEN5
names: Similarity
messages: Belongs to the CtsR family.

1504:CP523 RS15675
gene id: 1504:CP523_RS15675
uniprot id: A0A386PKE0
names: Function
messages: May be involved in the biosynthesis of molybdopterin.

1504:CP523 RS10070
gene id: 1504:CP523_RS10070
uniprot id: A0A386PJC9
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

1504:CP523 RS00690
gene id: 1504:CP523_RS00690
uniprot id: A0A386PDI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1504:CP523 RS13525
gene id: 1504:CP523_RS13525
uniprot id: A0A386PHU0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1504:CP523 RS14875
gene id: 1504:CP523_RS14875
uniprot id: A0A386PK00
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1504:CP523 RS02895
gene id: 1504:CP523_RS02895
uniprot id: A0A386PDS5
names: Similarity
messages: Belongs to the Fur family.

1504:CP523 RS07420
gene id: 1504:CP523_RS07420
uniprot id: A0A386PFT0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS02820
gene id: 1504:CP523_RS02820
uniprot id: A0A386PEL3
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

1504:CP523 RS09400
gene id: 1504:CP523_RS09400
uniprot id: A0A386PHS9
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS15600
gene id: 1504:CP523_RS15600
uniprot id: A0A386PIS6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS01080
gene id: 1504:CP523_RS01080
uniprot id: A0A386PEQ5
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1504:CP523 RS00845
gene id: 1504:CP523_RS00845
uniprot id: A0A386PDL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1504:CP523 RS11180
gene id: 1504:CP523_RS11180
uniprot id: A0A386PFT5
names: Similarity
messages: Belongs to the aerolysin family.

1504:CP523 RS13380
gene id: 1504:CP523_RS13380
uniprot id: A0A386PLR6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1504:CP523 RS00735
gene id: 1504:CP523_RS00735
uniprot id: A0A386PBF4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS12945
gene id: 1504:CP523_RS12945
uniprot id: A0A386PKI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1504:CP523 RS02495
gene id: 1504:CP523_RS02495
uniprot id: A0A386PEV6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1504:CP523 RS02835
gene id: 1504:CP523_RS02835
uniprot id: A0A386PDR5
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

1504:CP523 RS14470
gene id: 1504:CP523_RS14470
uniprot id: A0A386PJU2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1504:CP523 RS10910
gene id: 1504:CP523_RS10910
uniprot id: A0A386PIG6
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1504:CP523 RS11005
gene id: 1504:CP523_RS11005
uniprot id: A0A386PGI5
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1504:CP523 RS06135
gene id: 1504:CP523_RS06135
uniprot id: A0A386PFP7
names: Similarity
messages: Belongs to the SfsA family.

1504:CP523 RS11010
gene id: 1504:CP523_RS11010
uniprot id: A0A386PII3
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1504:CP523 RS07400
gene id: 1504:CP523_RS07400
uniprot id: A0A386PE34
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1504:CP523 RS14760
gene id: 1504:CP523_RS14760
uniprot id: A0A386PHK2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1504:CP523 RS08010
gene id: 1504:CP523_RS08010
uniprot id: A0A386PFZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1504:CP523 RS01145
gene id: 1504:CP523_RS01145
uniprot id: A0A386PE67
names: Similarity
messages: Belongs to the UPF0473 family.

1504:CP523 RS00725
gene id: 1504:CP523_RS00725
uniprot id: A0A386PDZ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1504:CP523 RS01045
gene id: 1504:CP523_RS01045
uniprot id: A0A386PBL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1504:CP523 RS03520
gene id: 1504:CP523_RS03520
uniprot id: A0A386PHE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

1504:CP523 RS02710
gene id: 1504:CP523_RS02710
uniprot id: A0A386PCE7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1504:CP523 RS06360
gene id: 1504:CP523_RS06360
uniprot id: A0A386PFU2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS02360
gene id: 1504:CP523_RS02360
uniprot id: A0A386PBS2
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1504:CP523 RS09740
gene id: 1504:CP523_RS09740
uniprot id: A0A386PFW7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS10770
gene id: 1504:CP523_RS10770
uniprot id: A0A386PFL3
names: Similarity
messages: Belongs to the DapA family.

1504:CP523 RS00665
gene id: 1504:CP523_RS00665
uniprot id: A0A386PEI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1504:CP523 RS02700
gene id: 1504:CP523_RS02700
uniprot id: A0A386PEZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

1504:CP523 RS02005
gene id: 1504:CP523_RS02005
uniprot id: A0A386PEL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1504:CP523 RS12695
gene id: 1504:CP523_RS12695
uniprot id: A0A386PKM1
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS06450
gene id: 1504:CP523_RS06450
uniprot id: A0A386PHS7
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS00655
gene id: 1504:CP523_RS00655
uniprot id: A0A386PCL6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1504:CP523 RS00920
gene id: 1504:CP523_RS00920
uniprot id: A0A386PEM8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1504:CP523 RS05095
gene id: 1504:CP523_RS05095
uniprot id: A0A386PFV2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1504:CP523 RS00975
gene id: 1504:CP523_RS00975
uniprot id: A0A386PEN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1504:CP523 RS14835
gene id: 1504:CP523_RS14835
uniprot id: A0A386PKT4
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

1504:CP523 RS08540
gene id: 1504:CP523_RS08540
uniprot id: A0A386PJT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1504:CP523 RS11890
gene id: 1504:CP523_RS11890
uniprot id: A0A386PLQ9
names: Similarity
messages: Belongs to the peptidase S16 family.

1504:CP523 RS15125
gene id: 1504:CP523_RS15125
uniprot id: A0A386PLB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1504:CP523 RS12530
gene id: 1504:CP523_RS12530
uniprot id: A0A386PII7
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1504:CP523 RS14350
gene id: 1504:CP523_RS14350
uniprot id: A0A386PL10
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS09000
gene id: 1504:CP523_RS09000
uniprot id: A0A386PIQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1504:CP523 RS02060
gene id: 1504:CP523_RS02060
uniprot id: A0A386PEN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1504:CP523 RS02195
gene id: 1504:CP523_RS02195
uniprot id: A0A386PDF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1504:CP523 RS05865
gene id: 1504:CP523_RS05865
uniprot id: A0A386PG78
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1504:CP523 RS06580
gene id: 1504:CP523_RS06580
uniprot id: A0A386PFE0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1504:CP523 RS12190
gene id: 1504:CP523_RS12190
uniprot id: A0A386PH45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

1504:CP523 RS06180
gene id: 1504:CP523_RS06180
uniprot id: A0A386PHN2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1504:CP523 RS08935
gene id: 1504:CP523_RS08935
uniprot id: A0A386PJZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1504:CP523 RS01785
gene id: 1504:CP523_RS01785
uniprot id: A0A386PGH2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1504:CP523 RS09065
gene id: 1504:CP523_RS09065
uniprot id: A0A386PES9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1504:CP523 RS13705
gene id: 1504:CP523_RS13705
uniprot id: A0A386PJG7
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1504:CP523 RS11400
gene id: 1504:CP523_RS11400
uniprot id: A0A386PK10
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1504:CP523 RS01670
gene id: 1504:CP523_RS01670
uniprot id: A0A386PCQ3
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1504:CP523 RS11415
gene id: 1504:CP523_RS11415
uniprot id: A0A386PKX6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS08670
gene id: 1504:CP523_RS08670
uniprot id: A0A386PHY7
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1504:CP523 RS01140
gene id: 1504:CP523_RS01140
uniprot id: A0A386PCF2
names: Similarity
messages: Belongs to the Fur family.

1504:CP523 RS02545
gene id: 1504:CP523_RS02545
uniprot id: A0A386PEW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1504:CP523 RS14230
gene id: 1504:CP523_RS14230
uniprot id: A0A386PLU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1504:CP523 RS02125
gene id: 1504:CP523_RS02125
uniprot id: A0A386PE80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

1504:CP523 RS13975
gene id: 1504:CP523_RS13975
uniprot id: A0A386PI13
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1504:CP523 RS10080
gene id: 1504:CP523_RS10080
uniprot id: A0A386PIM1
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1504:CP523 RS08795
gene id: 1504:CP523_RS08795
uniprot id: A0A386PEN9
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1504:CP523 RS03610
gene id: 1504:CP523_RS03610
uniprot id: A0A386PDS3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1504:CP523 RS07285
gene id: 1504:CP523_RS07285
uniprot id: A0A386PEM5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1504:CP523 RS11525
gene id: 1504:CP523_RS11525
uniprot id: A0A386PGT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1504:CP523 RS15695
gene id: 1504:CP523_RS15695
uniprot id: A0A386PJS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1504:CP523 RS15130
gene id: 1504:CP523_RS15130
uniprot id: A0A386PHU3
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1504:CP523 RS10610
gene id: 1504:CP523_RS10610
uniprot id: A0A386PFI5
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1504:CP523 RS12390
gene id: 1504:CP523_RS12390
uniprot id: A0A386PL97
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1504:CP523 RS03680
gene id: 1504:CP523_RS03680
uniprot id: A0A386PHH4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1504:CP523 RS09125
gene id: 1504:CP523_RS09125
uniprot id: A0A386PGL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1504:CP523 RS03205
gene id: 1504:CP523_RS03205
uniprot id: A0A386PC62
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1504:CP523 RS02540
gene id: 1504:CP523_RS02540
uniprot id: A0A386PD61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1504:CP523 RS09045
gene id: 1504:CP523_RS09045
uniprot id: A0A386PHL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1504:CP523 RS02155
gene id: 1504:CP523_RS02155
uniprot id: A0A386PFA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1504:CP523 RS03355
gene id: 1504:CP523_RS03355
uniprot id: A0A386PEW0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DbpA subfamily.
messages: Contains an N-terminal domain that binds non-specifically to RNA and a C-terminal domain that binds specifically and tightly to hairpin 92 of 23S rRNA.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes.

1504:CP523 RS15105
gene id: 1504:CP523_RS15105
uniprot id: A0A386PMF5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1504:CP523 RS11410
gene id: 1504:CP523_RS11410
uniprot id: A0A386PJ78
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1504:CP523 RS10105
gene id: 1504:CP523_RS10105
uniprot id: A0A386PFA3
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS07590
gene id: 1504:CP523_RS07590
uniprot id: A0A386PES8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS11775
gene id: 1504:CP523_RS11775
uniprot id: A0A386PG66
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

1504:CP523 RS08125
gene id: 1504:CP523_RS08125
uniprot id: A0A386PH59
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1504:CP523 RS13970
gene id: 1504:CP523_RS13970
uniprot id: A0A386PLR7
names: Function
names: Similarity
messages: Belongs to the PyrI family.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

1504:CP523 RS03655
gene id: 1504:CP523_RS03655
uniprot id: A0A386PEE7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1504:CP523 RS04590
gene id: 1504:CP523_RS04590
uniprot id: A0A386PFY9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1504:CP523 RS07080
gene id: 1504:CP523_RS07080
uniprot id: A0A386PJ87
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1504:CP523 RS02850
gene id: 1504:CP523_RS02850
uniprot id: A0A386PDB7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1504:CP523 RS14405
gene id: 1504:CP523_RS14405
uniprot id: A0A386PL17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1504:CP523 RS01130
gene id: 1504:CP523_RS01130
uniprot id: A0A386PB58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1504:CP523 RS08970
gene id: 1504:CP523_RS08970
uniprot id: A0A386PIS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1504:CP523 RS10685
gene id: 1504:CP523_RS10685
uniprot id: A0A386PHG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1504:CP523 RS05115
gene id: 1504:CP523_RS05115
uniprot id: A0A386PD34
names: Similarity
messages: Belongs to the CpsD/CapB family.

1504:CP523 RS13010
gene id: 1504:CP523_RS13010
uniprot id: A0A386PJ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1504:CP523 RS09650
gene id: 1504:CP523_RS09650
uniprot id: A0A386PHK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1504:CP523 RS04285
gene id: 1504:CP523_RS04285
uniprot id: A0A386PES2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS13490
gene id: 1504:CP523_RS13490
uniprot id: A0A386PJD3
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS00695
gene id: 1504:CP523_RS00695
uniprot id: A0A386PF08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1504:CP523 RS06435
gene id: 1504:CP523_RS06435
uniprot id: A0A386PJ09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1504:CP523 RS02890
gene id: 1504:CP523_RS02890
uniprot id: A0A386PC14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1504:CP523 RS12395
gene id: 1504:CP523_RS12395
uniprot id: A0A386PH79
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

1504:CP523 RS00150
gene id: 1504:CP523_RS00150
uniprot id: A0A386PEQ2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1504:CP523 RS01000
gene id: 1504:CP523_RS01000
uniprot id: A0A386PDP8
names: Similarity
messages: Belongs to the asparaginase 1 family.

1504:CP523 RS08650
gene id: 1504:CP523_RS08650
uniprot id: A0A386PH19
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1504:CP523 RS06475
gene id: 1504:CP523_RS06475
uniprot id: A0A386PHQ4
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS08090
gene id: 1504:CP523_RS08090
uniprot id: A0A386PEC2
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1504:CP523 RS10015
gene id: 1504:CP523_RS10015
uniprot id: A0A386PJB7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1504:CP523 RS08570
gene id: 1504:CP523_RS08570
uniprot id: A0A386PEK6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1504:CP523 RS02010
gene id: 1504:CP523_RS02010
uniprot id: A0A386PGL2
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1504:CP523 RS09080
gene id: 1504:CP523_RS09080
uniprot id: A0A386PI70
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1504:CP523 RS04045
gene id: 1504:CP523_RS04045
uniprot id: A0A386PHP5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1504:CP523 RS03935
gene id: 1504:CP523_RS03935
uniprot id: A0A386PDY6
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS05160
gene id: 1504:CP523_RS05160
uniprot id: A0A386PF87
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.

1504:CP523 RS04100
gene id: 1504:CP523_RS04100
uniprot id: A0A386PD39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1504:CP523 RS09655
gene id: 1504:CP523_RS09655
uniprot id: A0A386PF30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1504:CP523 RS02560
gene id: 1504:CP523_RS02560
uniprot id: A0A386PCC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1504:CP523 RS01155
gene id: 1504:CP523_RS01155
uniprot id: A0A386PBN6
names: Similarity
messages: Belongs to the UPF0297 family.

1504:CP523 RS01015
gene id: 1504:CP523_RS01015
uniprot id: A0A386PCT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1504:CP523 RS02590
gene id: 1504:CP523_RS02590
uniprot id: A0A386PFI0
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1504:CP523 RS07085
gene id: 1504:CP523_RS07085
uniprot id: A0A386PEJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1504:CP523 RS08205
gene id: 1504:CP523_RS08205
uniprot id: A0A386PED9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1504:CP523 RS00750
gene id: 1504:CP523_RS00750
uniprot id: A0A386PAY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.

1504:CP523 RS07065
gene id: 1504:CP523_RS07065
uniprot id: A0A386PHZ2
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS08550
gene id: 1504:CP523_RS08550
uniprot id: A0A386PHC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

1504:CP523 RS03115
gene id: 1504:CP523_RS03115
uniprot id: A0A386PC54
names: Similarity
messages: Belongs to the peptidase S33 family.

1504:CP523 RS10125
gene id: 1504:CP523_RS10125
uniprot id: A0A386PH52
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1504:CP523 RS10340
gene id: 1504:CP523_RS10340
uniprot id: A0A386PHW1
names: Subcellular Location Annotation
messages: cell wall

1504:CP523 RS01710
gene id: 1504:CP523_RS01710
uniprot id: A0A386PBG4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1504:CP523 RS15115
gene id: 1504:CP523_RS15115
uniprot id: A0A386PIK9
names: Similarity
messages: Belongs to the TlyA family.

1504:CP523 RS14960
gene id: 1504:CP523_RS14960
uniprot id: A0A386PK46
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1504:CP523 RS14755
gene id: 1504:CP523_RS14755
uniprot id: A0A386PJY1
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS07860
gene id: 1504:CP523_RS07860
uniprot id: A0A386PE90
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1504:CP523 RS09055
gene id: 1504:CP523_RS09055
uniprot id: A0A386PET7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1504:CP523 RS14955
gene id: 1504:CP523_RS14955
uniprot id: A0A386PII6
names: Subcellular Location Annotation
messages: Cytoplasm

1504:CP523 RS05920
gene id: 1504:CP523_RS05920
uniprot id: A0A386PHI6
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS00560
gene id: 1504:CP523_RS00560
uniprot id: A0A386PEG0
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

1504:CP523 RS06095
gene id: 1504:CP523_RS06095
uniprot id: A0A386PHI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1504:CP523 RS15445
gene id: 1504:CP523_RS15445
uniprot id: A0A386PM55
names: Similarity
messages: Belongs to the manganese catalase family.

1504:CP523 RS12975
gene id: 1504:CP523_RS12975
uniprot id: A0A386PJX1
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1504:CP523 RS12440
gene id: 1504:CP523_RS12440
uniprot id: A0A386PLA0
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1504:CP523 RS00125
gene id: 1504:CP523_RS00125
uniprot id: A0A386PBP2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1504:CP523 RS03195
gene id: 1504:CP523_RS03195
uniprot id: A0A386PET0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

1504:CP523 RS11260
gene id: 1504:CP523_RS11260
uniprot id: A0A386PGN3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1504:CP523 RS05475
gene id: 1504:CP523_RS05475
uniprot id: A0A386PDU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1504:CP523 RS12950
gene id: 1504:CP523_RS12950
uniprot id: A0A386PGQ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1504:CP523 RS10820
gene id: 1504:CP523_RS10820
uniprot id: A0A386PFM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1504:CP523 RS10430
gene id: 1504:CP523_RS10430
uniprot id: A0A386PJF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1504:CP523 RS13700
gene id: 1504:CP523_RS13700
uniprot id: A0A386PH37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1504:CP523 RS08665
gene id: 1504:CP523_RS08665
uniprot id: A0A386PGB9
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1504:CP523 RS02740
gene id: 1504:CP523_RS02740
uniprot id: A0A386PBY7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1504:CP523 RS01225
gene id: 1504:CP523_RS01225
uniprot id: A0A386PB70
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1504:CP523 RS04050
gene id: 1504:CP523_RS04050
uniprot id: A0A386PD29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1504:CP523 RS11120
gene id: 1504:CP523_RS11120
uniprot id: A0A386PFT7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1504:CP523 RS07140
gene id: 1504:CP523_RS07140
uniprot id: A0A386PLB1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1504:CP523 RS12060
gene id: 1504:CP523_RS12060
uniprot id: A0A386PKB1
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

1504:CP523 RS14725
gene id: 1504:CP523_RS14725
uniprot id: A0A386PKS3
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1504:CP523 RS07680
gene id: 1504:CP523_RS07680
uniprot id: A0A386PFW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1504:CP523 RS02500
gene id: 1504:CP523_RS02500
uniprot id: A0A386PGU8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1504:CP523 RS01210
gene id: 1504:CP523_RS01210
uniprot id: A0A386PBP7
names: Function
names: Similarity
names: Subunit
messages: Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
messages: Belongs to the HutP family.
messages: Homohexamer.

1504:CP523 RS12165
gene id: 1504:CP523_RS12165
uniprot id: A0A386PGA9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS01250
gene id: 1504:CP523_RS01250
uniprot id: A0A386PE84
names: Similarity
messages: Belongs to the fabD family.

1504:CP523 RS10755
gene id: 1504:CP523_RS10755
uniprot id: A0A386PID4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1504:CP523 RS07585
gene id: 1504:CP523_RS07585
uniprot id: A0A386PJE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1504:CP523 RS00075
gene id: 1504:CP523_RS00075
uniprot id: A0A386PBM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1504:CP523 RS09155
gene id: 1504:CP523_RS09155
uniprot id: A0A386PEV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

1504:CP523 RS12210
gene id: 1504:CP523_RS12210
uniprot id: A0A386PIV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

1504:CP523 RS14800
gene id: 1504:CP523_RS14800
uniprot id: A0A386PK22
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1504:CP523 RS14775
gene id: 1504:CP523_RS14775
uniprot id: A0A386PJD2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

1504:CP523 RS02385
gene id: 1504:CP523_RS02385
uniprot id: A0A386PGS7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1504:CP523 RS00970
gene id: 1504:CP523_RS00970
uniprot id: A0A386PB30
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS00160
gene id: 1504:CP523_RS00160
uniprot id: A0A386PCD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1504:CP523 RS10120
gene id: 1504:CP523_RS10120
uniprot id: A0A386PJD8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1504:CP523 RS09210
gene id: 1504:CP523_RS09210
uniprot id: A0A386PHC1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1504:CP523 RS14215
gene id: 1504:CP523_RS14215
uniprot id: A0A386PL77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1504:CP523 RS01265
gene id: 1504:CP523_RS01265
uniprot id: A0A386PDT9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1504:CP523 RS02925
gene id: 1504:CP523_RS02925
uniprot id: A0A386PH27
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS05355
gene id: 1504:CP523_RS05355
uniprot id: A0A386PDS4
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

1504:CP523 RS07540
gene id: 1504:CP523_RS07540
uniprot id: A0A386PER5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1504:CP523 RS08950
gene id: 1504:CP523_RS08950
uniprot id: A0A386PIP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1504:CP523 RS02305
gene id: 1504:CP523_RS02305
uniprot id: A0A386PFD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1504:CP523 RS09510
gene id: 1504:CP523_RS09510
uniprot id: A0A386PJ55
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS14690
gene id: 1504:CP523_RS14690
uniprot id: A0A386PK03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1504:CP523 RS01285
gene id: 1504:CP523_RS01285
uniprot id: A0A386PB87
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1504:CP523 RS04060
gene id: 1504:CP523_RS04060
uniprot id: A0A386PGN2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1504:CP523 RS00155
gene id: 1504:CP523_RS00155
uniprot id: A0A386PAL6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1504:CP523 RS01755
gene id: 1504:CP523_RS01755
uniprot id: A0A386PBG2
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

1504:CP523 RS14910
gene id: 1504:CP523_RS14910
uniprot id: A0A386PK39
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS10840
gene id: 1504:CP523_RS10840
uniprot id: A0A386PHK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1504:CP523 RS01365
gene id: 1504:CP523_RS01365
uniprot id: A0A386PDV9
names: Function
names: Similarity
names: Subunit
messages: In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.
messages: Monomer.
messages: Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine.

1504:CP523 RS09215
gene id: 1504:CP523_RS09215
uniprot id: A0A386PEV5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1504:CP523 RS09005
gene id: 1504:CP523_RS09005
uniprot id: A0A386PES6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1504:CP523 RS06355
gene id: 1504:CP523_RS06355
uniprot id: A0A386PDN6
names: Similarity
messages: Belongs to the pyruvate kinase family.

1504:CP523 RS08535
gene id: 1504:CP523_RS08535
uniprot id: A0A386PHW0
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS12300
gene id: 1504:CP523_RS12300
uniprot id: A0A386PKA1
names: Similarity
messages: Belongs to the YjdM family.

1504:CP523 RS06975
gene id: 1504:CP523_RS06975
uniprot id: A0A386PEH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1504:CP523 RS02955
gene id: 1504:CP523_RS02955
uniprot id: A0A386PC27
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1504:CP523 RS08955
gene id: 1504:CP523_RS08955
uniprot id: A0A386PER8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1504:CP523 RS02825
gene id: 1504:CP523_RS02825
uniprot id: A0A386PG19
names: Similarity
messages: Belongs to the RecJ family.

1504:CP523 RS04145
gene id: 1504:CP523_RS04145
uniprot id: A0A386PHS1
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1504:CP523 RS07840
gene id: 1504:CP523_RS07840
uniprot id: A0A386PIA9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS00770
gene id: 1504:CP523_RS00770
uniprot id: A0A386PC84
names: Similarity
messages: Belongs to the UPF0102 family.

1504:CP523 RS03940
gene id: 1504:CP523_RS03940
uniprot id: A0A386PFM3
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS01765
gene id: 1504:CP523_RS01765
uniprot id: A0A386PBH5
names: Similarity
messages: Belongs to the GARS family.

1504:CP523 RS13925
gene id: 1504:CP523_RS13925
uniprot id: A0A386PI04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1504:CP523 RS09680
gene id: 1504:CP523_RS09680
uniprot id: A0A386PKA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS09700
gene id: 1504:CP523_RS09700
uniprot id: A0A386PJ50
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1504:CP523 RS09130
gene id: 1504:CP523_RS09130
uniprot id: A0A386PI82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1504:CP523 RS03760
gene id: 1504:CP523_RS03760
uniprot id: A0A386PCG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1504:CP523 RS14925
gene id: 1504:CP523_RS14925
uniprot id: A0A386PK07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

1504:CP523 RS00585
gene id: 1504:CP523_RS00585
uniprot id: A0A386PDG5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

1504:CP523 RS15670
gene id: 1504:CP523_RS15670
uniprot id: A0A386PI35
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1504:CP523 RS00230
gene id: 1504:CP523_RS00230
uniprot id: A0A386PEA1
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1504:CP523 RS06415
gene id: 1504:CP523_RS06415
uniprot id: A0A386PDN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1504:CP523 RS01980
gene id: 1504:CP523_RS01980
uniprot id: A0A386PDA9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1504:CP523 RS02160
gene id: 1504:CP523_RS02160
uniprot id: A0A386PCZ2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1504:CP523 RS12250
gene id: 1504:CP523_RS12250
uniprot id: A0A386PK95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1504:CP523 RS15030
gene id: 1504:CP523_RS15030
uniprot id: A0A386PK29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1504:CP523 RS03525
gene id: 1504:CP523_RS03525
uniprot id: A0A386PCT5
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1504:CP523 RS12435
gene id: 1504:CP523_RS12435
uniprot id: A0A386PJN9
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1504:CP523 RS00810
gene id: 1504:CP523_RS00810
uniprot id: A0A386PCP6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1504:CP523 RS14345
gene id: 1504:CP523_RS14345
uniprot id: A0A386PJV0
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1504:CP523 RS08660
gene id: 1504:CP523_RS08660
uniprot id: A0A386PIN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1504:CP523 RS09135
gene id: 1504:CP523_RS09135
uniprot id: A0A386PK24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1504:CP523 RS09265
gene id: 1504:CP523_RS09265
uniprot id: A0A386PEW5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

1504:CP523 RS07635
gene id: 1504:CP523_RS07635
uniprot id: A0A386PJF8
names: Similarity
messages: Belongs to the ParB family.

1504:CP523 RS01290
gene id: 1504:CP523_RS01290
uniprot id: A0A386PEU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1504:CP523 RS00995
gene id: 1504:CP523_RS00995
uniprot id: A0A386PBK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1504:CP523 RS11550
gene id: 1504:CP523_RS11550
uniprot id: A0A386PG15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1504:CP523 RS14210
gene id: 1504:CP523_RS14210
uniprot id: A0A386PHA8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1504:CP523 RS13980
gene id: 1504:CP523_RS13980
uniprot id: A0A386PJP8
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1504:CP523 RS03160
gene id: 1504:CP523_RS03160
uniprot id: A0A386PE55
names: Similarity
messages: Belongs to the RutC family.

1504:CP523 RS07675
gene id: 1504:CP523_RS07675
uniprot id: A0A386PI90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1504:CP523 RS08700
gene id: 1504:CP523_RS08700
uniprot id: A0A386PHE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1504:CP523 RS12040
gene id: 1504:CP523_RS12040
uniprot id: A0A386PGB1
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1504:CP523 RS15420
gene id: 1504:CP523_RS15420
uniprot id: A0A386PK91
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

1504:CP523 RS12815
gene id: 1504:CP523_RS12815
uniprot id: A0A386PLD0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1504:CP523 RS07440
gene id: 1504:CP523_RS07440
uniprot id: A0A386PGW2
names: Similarity
messages: Belongs to the peptidase S8 family.

1504:CP523 RS10855
gene id: 1504:CP523_RS10855
uniprot id: A0A386PGF6
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1504:CP523 RS12285
gene id: 1504:CP523_RS12285
uniprot id: A0A386PL84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YdjC deacetylase family.
messages: Homodimer.
messages: Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides.

1504:CP523 RS02275
gene id: 1504:CP523_RS02275
uniprot id: A0A386PC75
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1504:CP523 RS00175
gene id: 1504:CP523_RS00175
uniprot id: A0A386PBQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1504:CP523 RS01540
gene id: 1504:CP523_RS01540
uniprot id: A0A386PBD3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

1504:CP523 RS10150
gene id: 1504:CP523_RS10150
uniprot id: A0A386PJA5
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1504:CP523 RS12015
gene id: 1504:CP523_RS12015
uniprot id: A0A386PJH4
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1504:CP523 RS09880
gene id: 1504:CP523_RS09880
uniprot id: A0A386PH13
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

1504:CP523 RS10485
gene id: 1504:CP523_RS10485
uniprot id: A0A386PG79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1504:CP523 RS08850
gene id: 1504:CP523_RS08850
uniprot id: A0A386PH50
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1504:CP523 RS07650
gene id: 1504:CP523_RS07650
uniprot id: A0A386PGY9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1504:CP523 RS00730
gene id: 1504:CP523_RS00730
uniprot id: A0A386PFX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1504:CP523 RS08925
gene id: 1504:CP523_RS08925
uniprot id: A0A386PGH0
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1504:CP523 RS05265
gene id: 1504:CP523_RS05265
uniprot id: A0A386PD55
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS08310
gene id: 1504:CP523_RS08310
uniprot id: A0A386PEF8
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1504:CP523 RS14630
gene id: 1504:CP523_RS14630
uniprot id: A0A386PIC6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1504:CP523 RS07655
gene id: 1504:CP523_RS07655
uniprot id: A0A386PI94
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1504:CP523 RS00835
gene id: 1504:CP523_RS00835
uniprot id: A0A386PFZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1504:CP523 RS10190
gene id: 1504:CP523_RS10190
uniprot id: A0A386PG27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1504:CP523 RS02680
gene id: 1504:CP523_RS02680
uniprot id: A0A386PDN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1504:CP523 RS15095
gene id: 1504:CP523_RS15095
uniprot id: A0A386PJI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1504:CP523 RS07660
gene id: 1504:CP523_RS07660
uniprot id: A0A386PE68
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS08500
gene id: 1504:CP523_RS08500
uniprot id: A0A386PIK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1504:CP523 RS10235
gene id: 1504:CP523_RS10235
uniprot id: A0A386PKG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS14635
gene id: 1504:CP523_RS14635
uniprot id: A0A386PJZ6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1504:CP523 RS09340
gene id: 1504:CP523_RS09340
uniprot id: A0A386PFN8
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1504:CP523 RS06175
gene id: 1504:CP523_RS06175
uniprot id: A0A386PIA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1504:CP523 RS01040
gene id: 1504:CP523_RS01040
uniprot id: A0A386PG32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1504:CP523 RS10710
gene id: 1504:CP523_RS10710
uniprot id: A0A386PJJ6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1504:CP523 RS03875
gene id: 1504:CP523_RS03875
uniprot id: A0A386PG72
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS03865
gene id: 1504:CP523_RS03865
uniprot id: A0A386PEI7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1504:CP523 RS12505
gene id: 1504:CP523_RS12505
uniprot id: A0A386PKC5
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

1504:CP523 RS12905
gene id: 1504:CP523_RS12905
uniprot id: A0A386PGN7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1504:CP523 RS08415
gene id: 1504:CP523_RS08415
uniprot id: A0A386PIK1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1504:CP523 RS15080
gene id: 1504:CP523_RS15080
uniprot id: A0A386PK41
names: Similarity
messages: Belongs to the asp23 family.

1504:CP523 RS10465
gene id: 1504:CP523_RS10465
uniprot id: A0A386PHB6
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1504:CP523 RS00860
gene id: 1504:CP523_RS00860
uniprot id: A0A386PCQ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1504:CP523 RS00605
gene id: 1504:CP523_RS00605
uniprot id: A0A386PAV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1504:CP523 RS14250
gene id: 1504:CP523_RS14250
uniprot id: A0A386PHE2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1504:CP523 RS05250
gene id: 1504:CP523_RS05250
uniprot id: A0A386PDQ1
names: Similarity
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.

1504:CP523 RS03990
gene id: 1504:CP523_RS03990
uniprot id: A0A386PFN6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1504:CP523 RS07220
gene id: 1504:CP523_RS07220
uniprot id: A0A386PEL5
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1504:CP523 RS14270
gene id: 1504:CP523_RS14270
uniprot id: A0A386PJ63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS10805
gene id: 1504:CP523_RS10805
uniprot id: A0A386PGE6
names: Similarity
messages: Belongs to the creatininase superfamily.

1504:CP523 RS01890
gene id: 1504:CP523_RS01890
uniprot id: A0A386PEJ7
names: Similarity
messages: Belongs to the thioredoxin family.

1504:CP523 RS09180
gene id: 1504:CP523_RS09180
uniprot id: A0A386PI92
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1504:CP523 RS01100
gene id: 1504:CP523_RS01100
uniprot id: A0A386PG42
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1504:CP523 RS12360
gene id: 1504:CP523_RS12360
uniprot id: A0A386PGG1
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1504:CP523 RS13770
gene id: 1504:CP523_RS13770
uniprot id: A0A386PIZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

1504:CP523 RS05360
gene id: 1504:CP523_RS05360
uniprot id: A0A386PG03
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

1504:CP523 RS00745
gene id: 1504:CP523_RS00745
uniprot id: A0A386PF17
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1504:CP523 RS08005
gene id: 1504:CP523_RS08005
uniprot id: A0A386PID1
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS12510
gene id: 1504:CP523_RS12510
uniprot id: A0A386PGI7
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1504:CP523 RS04980
gene id: 1504:CP523_RS04980
uniprot id: A0A386PH32
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS03580
gene id: 1504:CP523_RS03580
uniprot id: A0A386PF05
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1504:CP523 RS06525
gene id: 1504:CP523_RS06525
uniprot id: A0A386PHR6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1504:CP523 RS03480
gene id: 1504:CP523_RS03480
uniprot id: A0A386PKJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1504:CP523 RS02615
gene id: 1504:CP523_RS02615
uniprot id: A0A386PEH0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1504:CP523 RS02530
gene id: 1504:CP523_RS02530
uniprot id: A0A386PBU4
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1504:CP523 RS08525
gene id: 1504:CP523_RS08525
uniprot id: A0A386PIL6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1504:CP523 RS13765
gene id: 1504:CP523_RS13765
uniprot id: A0A386PL18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

1504:CP523 RS14450
gene id: 1504:CP523_RS14450
uniprot id: A0A386PI95
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1504:CP523 RS10915
gene id: 1504:CP523_RS10915
uniprot id: A0A386PJN4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1504:CP523 RS02865
gene id: 1504:CP523_RS02865
uniprot id: A0A386PH17
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS02205
gene id: 1504:CP523_RS02205
uniprot id: A0A386PFA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

1504:CP523 RS14965
gene id: 1504:CP523_RS14965
uniprot id: A0A386PL92
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

1504:CP523 RS13945
gene id: 1504:CP523_RS13945
uniprot id: A0A386PJK2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS03465
gene id: 1504:CP523_RS03465
uniprot id: A0A386PHD4
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1504:CP523 RS01430
gene id: 1504:CP523_RS01430
uniprot id: A0A386PBB0
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS15430
gene id: 1504:CP523_RS15430
uniprot id: A0A386PLN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

1504:CP523 RS14740
gene id: 1504:CP523_RS14740
uniprot id: A0A386PK13
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1504:CP523 RS14050
gene id: 1504:CP523_RS14050
uniprot id: A0A386PJM0
names: Similarity
messages: Belongs to the IMPACT family.

1504:CP523 RS02120
gene id: 1504:CP523_RS02120
uniprot id: A0A386PC47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
messages: Cytoplasm

1504:CP523 RS09230
gene id: 1504:CP523_RS09230
uniprot id: A0A386PIA2
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1504:CP523 RS13465
gene id: 1504:CP523_RS13465
uniprot id: A0A386PHT0
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS14245
gene id: 1504:CP523_RS14245
uniprot id: A0A386PKZ0
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1504:CP523 RS13730
gene id: 1504:CP523_RS13730
uniprot id: A0A386PLP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1504:CP523 RS09105
gene id: 1504:CP523_RS09105
uniprot id: A0A386PEU9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1504:CP523 RS00760
gene id: 1504:CP523_RS00760
uniprot id: A0A386PAY6
names: Similarity
messages: Belongs to the DprA/Smf family.

1504:CP523 RS13940
gene id: 1504:CP523_RS13940
uniprot id: A0A386PH78
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1504:CP523 RS04185
gene id: 1504:CP523_RS04185
uniprot id: A0A386PGE0
names: Similarity
messages: Belongs to the thioredoxin family.

1504:CP523 RS10695
gene id: 1504:CP523_RS10695
uniprot id: A0A386PKN5
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1504:CP523 RS00865
gene id: 1504:CP523_RS00865
uniprot id: A0A386PB15
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1504:CP523 RS00780
gene id: 1504:CP523_RS00780
uniprot id: A0A386PFY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1504:CP523 RS10130
gene id: 1504:CP523_RS10130
uniprot id: A0A386PIM8
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1504:CP523 RS14790
gene id: 1504:CP523_RS14790
uniprot id: A0A386PLZ4
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

1504:CP523 RS15175
gene id: 1504:CP523_RS15175
uniprot id: A0A386PK78
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1504:CP523 RS10180
gene id: 1504:CP523_RS10180
uniprot id: A0A386PIN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1504:CP523 RS11075
gene id: 1504:CP523_RS11075
uniprot id: A0A386PIC5
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

1504:CP523 RS07090
gene id: 1504:CP523_RS07090
uniprot id: A0A386PGQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1504:CP523 RS14900
gene id: 1504:CP523_RS14900
uniprot id: A0A386PM07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1504:CP523 RS13500
gene id: 1504:CP523_RS13500
uniprot id: A0A386PKY0
names: Similarity
messages: Belongs to the UPF0473 family.

1504:CP523 RS10075
gene id: 1504:CP523_RS10075
uniprot id: A0A386PH42
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

1504:CP523 RS08825
gene id: 1504:CP523_RS08825
uniprot id: A0A386PJX4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1504:CP523 RS15780
gene id: 1504:CP523_RS15780
uniprot id: A0A386PKH0
names: Similarity
messages: Belongs to the UPF0371 family.

1504:CP523 RS14125
gene id: 1504:CP523_RS14125
uniprot id: A0A386PKI8
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1504:CP523 RS10560
gene id: 1504:CP523_RS10560
uniprot id: A0A386PI06
names: Similarity
messages: Belongs to the PspA/IM30 family.

1504:CP523 RS00470
gene id: 1504:CP523_RS00470
uniprot id: A0A386PDV4
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

1504:CP523 RS06850
gene id: 1504:CP523_RS06850
uniprot id: A0A386PG33
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1504:CP523 RS09225
gene id: 1504:CP523_RS09225
uniprot id: A0A386PGN8
names: Similarity
messages: Belongs to the ArsC family.

1504:CP523 RS11235
gene id: 1504:CP523_RS11235
uniprot id: A0A386PJY3
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS11720
gene id: 1504:CP523_RS11720
uniprot id: A0A386PI54
names: Function
names: Similarity
messages: Belongs to the IolE/MocC family.
messages: Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).

1504:CP523 RS05470
gene id: 1504:CP523_RS05470
uniprot id: A0A386PIH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1504:CP523 RS00980
gene id: 1504:CP523_RS00980
uniprot id: A0A386PCC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1504:CP523 RS13450
gene id: 1504:CP523_RS13450
uniprot id: A0A386PIV1
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS15820
gene id: 1504:CP523_RS15820
uniprot id: A0A386PLK5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1504:CP523 RS10800
gene id: 1504:CP523_RS10800
uniprot id: A0A386PKQ0
names: Similarity
messages: Belongs to the EamA transporter family.

1504:CP523 RS07560
gene id: 1504:CP523_RS07560
uniprot id: A0A386PGE8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1504:CP523 RS03265
gene id: 1504:CP523_RS03265
uniprot id: A0A386PE78
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1504:CP523 RS12380
gene id: 1504:CP523_RS12380
uniprot id: A0A386PIG4
names: Subcellular Location Annotation
messages: cell wall

1504:CP523 RS10595
gene id: 1504:CP523_RS10595
uniprot id: A0A386PGA4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1504:CP523 RS08410
gene id: 1504:CP523_RS08410
uniprot id: A0A386PEH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

1504:CP523 RS07550
gene id: 1504:CP523_RS07550
uniprot id: A0A386PI74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1504:CP523 RS14670
gene id: 1504:CP523_RS14670
uniprot id: A0A386PKR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1504:CP523 RS06965
gene id: 1504:CP523_RS06965
uniprot id: A0A386PH46
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS03720
gene id: 1504:CP523_RS03720
uniprot id: A0A386PDU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Cell membrane
messages: Membrane

1504:CP523 RS03065
gene id: 1504:CP523_RS03065
uniprot id: A0A386PFR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

1504:CP523 RS12125
gene id: 1504:CP523_RS12125
uniprot id: A0A386PJI8
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1504:CP523 RS02115
gene id: 1504:CP523_RS02115
uniprot id: A0A386PGN4
names: Similarity
messages: Belongs to the aldose epimerase family.

1504:CP523 RS09020
gene id: 1504:CP523_RS09020
uniprot id: A0A386PIT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1504:CP523 RS04055
gene id: 1504:CP523_RS04055
uniprot id: A0A386PFA5
names: Similarity
messages: Belongs to the EamA transporter family.

1504:CP523 RS14425
gene id: 1504:CP523_RS14425
uniprot id: A0A386PHE6
names: Similarity
messages: Belongs to the peptidase M16 family.

1504:CP523 RS02285
gene id: 1504:CP523_RS02285
uniprot id: A0A386PFS1
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1504:CP523 RS13805
gene id: 1504:CP523_RS13805
uniprot id: A0A386PJI4
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS04195
gene id: 1504:CP523_RS04195
uniprot id: A0A386PFT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1504:CP523 RS15700
gene id: 1504:CP523_RS15700
uniprot id: A0A386PL45
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1504:CP523 RS09620
gene id: 1504:CP523_RS09620
uniprot id: A0A386PIH4
names: Similarity
messages: Belongs to the SIS family. AgaS subfamily.

1504:CP523 RS09035
gene id: 1504:CP523_RS09035
uniprot id: A0A386PK06
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1504:CP523 RS06425
gene id: 1504:CP523_RS06425
uniprot id: A0A386PFB5
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1504:CP523 RS14695
gene id: 1504:CP523_RS14695
uniprot id: A0A386PL52
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1504:CP523 RS02200
gene id: 1504:CP523_RS02200
uniprot id: A0A386PBP5
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1504:CP523 RS14890
gene id: 1504:CP523_RS14890
uniprot id: A0A386PJF1
names: Similarity
messages: Belongs to the transpeptidase family.

1504:CP523 RS11660
gene id: 1504:CP523_RS11660
uniprot id: A0A386PI42
names: Similarity
messages: Belongs to the RNase H family.

1504:CP523 RS10255
gene id: 1504:CP523_RS10255
uniprot id: A0A386PFD5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS02790
gene id: 1504:CP523_RS02790
uniprot id: A0A386PBZ8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1504:CP523 RS00885
gene id: 1504:CP523_RS00885
uniprot id: A0A386PG00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1504:CP523 RS08815
gene id: 1504:CP523_RS08815
uniprot id: A0A386PGE9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1504:CP523 RS07305
gene id: 1504:CP523_RS07305
uniprot id: A0A386PE11
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1504:CP523 RS05170
gene id: 1504:CP523_RS05170
uniprot id: A0A386PD43
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1504:CP523 RS08645
gene id: 1504:CP523_RS08645
uniprot id: A0A386PEM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1504:CP523 RS11500
gene id: 1504:CP523_RS11500
uniprot id: A0A386PG08
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS06470
gene id: 1504:CP523_RS06470
uniprot id: A0A386PDP6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1504:CP523 RS15685
gene id: 1504:CP523_RS15685
uniprot id: A0A386PI07
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1504:CP523 RS10580
gene id: 1504:CP523_RS10580
uniprot id: A0A386PHD5
names: Similarity
messages: Belongs to the pyruvate kinase family.

1504:CP523 RS06750
gene id: 1504:CP523_RS06750
uniprot id: A0A386PG21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1504:CP523 RS03985
gene id: 1504:CP523_RS03985
uniprot id: A0A386PDZ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1504:CP523 RS03845
gene id: 1504:CP523_RS03845
uniprot id: A0A386PCZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1504:CP523 RS01135
gene id: 1504:CP523_RS01135
uniprot id: A0A386PER4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1504:CP523 RS05985
gene id: 1504:CP523_RS05985
uniprot id: A0A386PFM1
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1504:CP523 RS02620
gene id: 1504:CP523_RS02620
uniprot id: A0A386PFX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1504:CP523 RS08945
gene id: 1504:CP523_RS08945
uniprot id: A0A386PHJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1504:CP523 RS11405
gene id: 1504:CP523_RS11405
uniprot id: A0A386PHY3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

1504:CP523 RS08430
gene id: 1504:CP523_RS08430
uniprot id: A0A386PJS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1504:CP523 RS03860
gene id: 1504:CP523_RS03860
uniprot id: A0A386PCH9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1504:CP523 RS12845
gene id: 1504:CP523_RS12845
uniprot id: A0A386PJ29
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS15200
gene id: 1504:CP523_RS15200
uniprot id: A0A386PK60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

1504:CP523 RS06480
gene id: 1504:CP523_RS06480
uniprot id: A0A386PFC3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1504:CP523 RS15800
gene id: 1504:CP523_RS15800
uniprot id: A0A386PL62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1504:CP523 RS01775
gene id: 1504:CP523_RS01775
uniprot id: A0A386PCS0
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS04545
gene id: 1504:CP523_RS04545
uniprot id: A0A386PGW1
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS01175
gene id: 1504:CP523_RS01175
uniprot id: A0A386PCW4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS05120
gene id: 1504:CP523_RS05120
uniprot id: A0A386PH08
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS02730
gene id: 1504:CP523_RS02730
uniprot id: A0A386PBY5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

1504:CP523 RS07290
gene id: 1504:CP523_RS07290
uniprot id: A0A386PGT8
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS11420
gene id: 1504:CP523_RS11420
uniprot id: A0A386PGR6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1504:CP523 RS14465
gene id: 1504:CP523_RS14465
uniprot id: A0A386PHI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

1504:CP523 RS14045
gene id: 1504:CP523_RS14045
uniprot id: A0A386PH99
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1504:CP523 RS09945
gene id: 1504:CP523_RS09945
uniprot id: A0A386PHN9
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1504:CP523 RS07890
gene id: 1504:CP523_RS07890
uniprot id: A0A386PFX0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of AddA and AddB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.

1504:CP523 RS07525
gene id: 1504:CP523_RS07525
uniprot id: A0A386PFT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

1504:CP523 RS05420
gene id: 1504:CP523_RS05420
uniprot id: A0A386PIG9
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1504:CP523 RS08915
gene id: 1504:CP523_RS08915
uniprot id: A0A386PEQ1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1504:CP523 RS03665
gene id: 1504:CP523_RS03665
uniprot id: A0A386PG28
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS02695
gene id: 1504:CP523_RS02695
uniprot id: A0A386PD90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1504:CP523 RS08470
gene id: 1504:CP523_RS08470
uniprot id: A0A386PG87
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1504:CP523 RS05740
gene id: 1504:CP523_RS05740
uniprot id: A0A386PDY2
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1504:CP523 RS00635
gene id: 1504:CP523_RS00635
uniprot id: A0A386PBD7
names: Similarity
messages: Belongs to the peptidase M16 family.

1504:CP523 RS07395
gene id: 1504:CP523_RS07395
uniprot id: A0A386PI56
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1504:CP523 RS10185
gene id: 1504:CP523_RS10185
uniprot id: A0A386PKG1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1504:CP523 RS00755
gene id: 1504:CP523_RS00755
uniprot id: A0A386PCN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1504:CP523 RS00705
gene id: 1504:CP523_RS00705
uniprot id: A0A386PCM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1504:CP523 RS06375
gene id: 1504:CP523_RS06375
uniprot id: A0A386PFA4
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS05105
gene id: 1504:CP523_RS05105
uniprot id: A0A386PD27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1504:CP523 RS00955
gene id: 1504:CP523_RS00955
uniprot id: A0A386PB27
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1504:CP523 RS02255
gene id: 1504:CP523_RS02255
uniprot id: A0A386PFB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1504:CP523 RS06105
gene id: 1504:CP523_RS06105
uniprot id: A0A386PGR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1504:CP523 RS15725
gene id: 1504:CP523_RS15725
uniprot id: A0A386PI45
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1504:CP523 RS01335
gene id: 1504:CP523_RS01335
uniprot id: A0A386PB97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1504:CP523 RS01030
gene id: 1504:CP523_RS01030
uniprot id: A0A386PCD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1504:CP523 RS11150
gene id: 1504:CP523_RS11150
uniprot id: A0A386PKU5
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1504:CP523 RS12965
gene id: 1504:CP523_RS12965
uniprot id: A0A386PKR3
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1504:CP523 RS12970
gene id: 1504:CP523_RS12970
uniprot id: A0A386PIN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1504:CP523 RS02475
gene id: 1504:CP523_RS02475
uniprot id: A0A386PDJ9
names: Similarity
messages: Belongs to the UPF0735 family.

1504:CP523 RS03630
gene id: 1504:CP523_RS03630
uniprot id: A0A386PCV4
names: Similarity
messages: Belongs to the peptidase S8 family.

1504:CP523 RS07570
gene id: 1504:CP523_RS07570
uniprot id: A0A386PI71
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1504:CP523 RS08750
gene id: 1504:CP523_RS08750
uniprot id: A0A386PH33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1504:CP523 RS07130
gene id: 1504:CP523_RS07130
uniprot id: A0A386PFM9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1504:CP523 RS10205
gene id: 1504:CP523_RS10205
uniprot id: A0A386PFC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1504:CP523 RS08515
gene id: 1504:CP523_RS08515
uniprot id: A0A386PGZ5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS00315
gene id: 1504:CP523_RS00315
uniprot id: A0A386PEU3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1504:CP523 RS01425
gene id: 1504:CP523_RS01425
uniprot id: A0A386PFD2
names: Subcellular Location Annotation
messages: Cell membrane

1504:CP523 RS01125
gene id: 1504:CP523_RS01125
uniprot id: A0A386PCV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1504:CP523 RS11785
gene id: 1504:CP523_RS11785
uniprot id: A0A386PG50
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

1504:CP523 RS14025
gene id: 1504:CP523_RS14025
uniprot id: A0A386PK26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1504:CP523 RS06990
gene id: 1504:CP523_RS06990
uniprot id: A0A386PDX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1504:CP523 RS01465
gene id: 1504:CP523_RS01465
uniprot id: A0A386PBU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the precorrin methyltransferase family.
messages: Homodimer.
messages: Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway.

1504:CP523 RS09280
gene id: 1504:CP523_RS09280
uniprot id: A0A386PIB2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1504:CP523 RS11240
gene id: 1504:CP523_RS11240
uniprot id: A0A386PHU7
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

1504:CP523 RS09075
gene id: 1504:CP523_RS09075
uniprot id: A0A386PGK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1504:CP523 RS02035
gene id: 1504:CP523_RS02035
uniprot id: A0A386PDB9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

1504:CP523 RS12890
gene id: 1504:CP523_RS12890
uniprot id: A0A386PKH3
names: Similarity
messages: Belongs to the ThiD family.

1504:CP523 RS15750
gene id: 1504:CP523_RS15750
uniprot id: A0A386PL54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1504:CP523 RS14015
gene id: 1504:CP523_RS14015
uniprot id: A0A386PKH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1504:CP523 RS06505
gene id: 1504:CP523_RS06505
uniprot id: A0A386PHT4
names: Similarity
messages: Belongs to the peptidase S41A family.

1504:CP523 RS09050
gene id: 1504:CP523_RS09050
uniprot id: A0A386PIR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1504:CP523 RS01070
gene id: 1504:CP523_RS01070
uniprot id: A0A386PB50
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1504:CP523 RS02565
gene id: 1504:CP523_RS02565
uniprot id: A0A386PEG2
names: Similarity
messages: Belongs to the MotB family.

1504:CP523 RS14055
gene id: 1504:CP523_RS14055
uniprot id: A0A386PH81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1504:CP523 RS08760
gene id: 1504:CP523_RS08760
uniprot id: A0A386PIN9
names: Similarity
messages: Belongs to the peptidase M20A family.

1504:CP523 RS11040
gene id: 1504:CP523_RS11040
uniprot id: A0A386PHP4
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1504:CP523 RS12235
gene id: 1504:CP523_RS12235
uniprot id: A0A386PL78
names: Subcellular Location Annotation
messages: Cytoplasm

1504:CP523 RS07645
gene id: 1504:CP523_RS07645
uniprot id: A0A386PIB3
names: Similarity
messages: Belongs to the ParB family.

1504:CP523 RS08870
gene id: 1504:CP523_RS08870
uniprot id: A0A386PI19
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1504:CP523 RS07125
gene id: 1504:CP523_RS07125
uniprot id: A0A386PI02
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1504:CP523 RS01995
gene id: 1504:CP523_RS01995
uniprot id: A0A386PF74
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1504:CP523 RS06910
gene id: 1504:CP523_RS06910
uniprot id: A0A386PEG5
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1504:CP523 RS12315
gene id: 1504:CP523_RS12315
uniprot id: A0A386PIW4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1504:CP523 RS08930
gene id: 1504:CP523_RS08930
uniprot id: A0A386PI33
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1504:CP523 RS14865
gene id: 1504:CP523_RS14865
uniprot id: A0A386PHP3
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1504:CP523 RS11565
gene id: 1504:CP523_RS11565
uniprot id: A0A386PJB0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS04125
gene id: 1504:CP523_RS04125
uniprot id: A0A386PCN4
names: Similarity
messages: Belongs to the UPF0229 family.

1504:CP523 RS07295
gene id: 1504:CP523_RS07295
uniprot id: A0A386PI40
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1504:CP523 RS14120
gene id: 1504:CP523_RS14120
uniprot id: A0A386PJ36
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1504:CP523 RS06510
gene id: 1504:CP523_RS06510
uniprot id: A0A386PDR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

1504:CP523 RS01095
gene id: 1504:CP523_RS01095
uniprot id: A0A386PE58
names: Similarity
messages: Belongs to the GSP E family.

1504:CP523 RS01195
gene id: 1504:CP523_RS01195
uniprot id: A0A386PCG0
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1504:CP523 RS09295
gene id: 1504:CP523_RS09295
uniprot id: A0A386PHR1
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1504:CP523 RS14460
gene id: 1504:CP523_RS14460
uniprot id: A0A386PL25
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1504:CP523 RS09175
gene id: 1504:CP523_RS09175
uniprot id: A0A386PGM6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1504:CP523 RS08355
gene id: 1504:CP523_RS08355
uniprot id: A0A386PGV8
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1504:CP523 RS09200
gene id: 1504:CP523_RS09200
uniprot id: A0A386PIT8
names: Similarity
messages: Belongs to the class-I fumarase family.

1504:CP523 RS09095
gene id: 1504:CP523_RS09095
uniprot id: A0A386PHM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1504:CP523 RS12495
gene id: 1504:CP523_RS12495
uniprot id: A0A386PH98
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1504:CP523 RS01490
gene id: 1504:CP523_RS01490
uniprot id: A0A386PBC4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1504:CP523 RS00325
gene id: 1504:CP523_RS00325
uniprot id: A0A386PCF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1504:CP523 RS01215
gene id: 1504:CP523_RS01215
uniprot id: A0A386PDT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1504:CP523 RS02250
gene id: 1504:CP523_RS02250
uniprot id: A0A386PBQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1504:CP523 RS01165
gene id: 1504:CP523_RS01165
uniprot id: A0A386PF89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1504:CP523 RS08560
gene id: 1504:CP523_RS08560
uniprot id: A0A386PEL0
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS14200
gene id: 1504:CP523_RS14200
uniprot id: A0A386PHD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1504:CP523 RS11440
gene id: 1504:CP523_RS11440
uniprot id: A0A386PIJ4
names: Similarity
messages: Belongs to the GerABKA family.

1504:CP523 RS12895
gene id: 1504:CP523_RS12895
uniprot id: A0A386PGP8
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1504:CP523 RS09160
gene id: 1504:CP523_RS09160
uniprot id: A0A386PHB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

1504:CP523 RS00795
gene id: 1504:CP523_RS00795
uniprot id: A0A386PF27
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1504:CP523 RS00670
gene id: 1504:CP523_RS00670
uniprot id: A0A386PC00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1504:CP523 RS12825
gene id: 1504:CP523_RS12825
uniprot id: A0A386PHF3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1504:CP523 RS14205
gene id: 1504:CP523_RS14205
uniprot id: A0A386PJP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1504:CP523 RS14615
gene id: 1504:CP523_RS14615
uniprot id: A0A386PJB1
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS02280
gene id: 1504:CP523_RS02280
uniprot id: A0A386PEB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1504:CP523 RS08280
gene id: 1504:CP523_RS08280
uniprot id: A0A386PJP4
names: Similarity
messages: Belongs to the peptidase M24B family.

1504:CP523 RS10145
gene id: 1504:CP523_RS10145
uniprot id: A0A386PI28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1504:CP523 RS09630
gene id: 1504:CP523_RS09630
uniprot id: A0A386PFU0
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1504:CP523 RS02460
gene id: 1504:CP523_RS02460
uniprot id: A0A386PEE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1504:CP523 RS01345
gene id: 1504:CP523_RS01345
uniprot id: A0A386PCI6
names: Similarity
messages: Belongs to the transpeptidase family.

1504:CP523 RS09255
gene id: 1504:CP523_RS09255
uniprot id: A0A386PEX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1504:CP523 RS07715
gene id: 1504:CP523_RS07715
uniprot id: A0A386PE77
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1504:CP523 RS12455
gene id: 1504:CP523_RS12455
uniprot id: A0A386PKB9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes activation of the choline trimethylamine-lyase CutC under anaerobic conditions by generation of an organic free radical on a glycine residue, via an homolytic cleavage of S-adenosyl-L-methionine (SAM).

1504:CP523 RS10195
gene id: 1504:CP523_RS10195
uniprot id: A0A386PI39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1504:CP523 RS01010
gene id: 1504:CP523_RS01010
uniprot id: A0A386PB37
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

1504:CP523 RS10135
gene id: 1504:CP523_RS10135
uniprot id: A0A386PKF4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1504:CP523 RS09120
gene id: 1504:CP523_RS09120
uniprot id: A0A386PIZ6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1504:CP523 RS14430
gene id: 1504:CP523_RS14430
uniprot id: A0A386PLB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1504:CP523 RS13725
gene id: 1504:CP523_RS13725
uniprot id: A0A386PK80
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1504:CP523 RS10795
gene id: 1504:CP523_RS10795
uniprot id: A0A386PIX8
names: Similarity
messages: Belongs to the CdaR family.

1504:CP523 RS03980
gene id: 1504:CP523_RS03980
uniprot id: A0A386PG95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1504:CP523 RS01050
gene id: 1504:CP523_RS01050
uniprot id: A0A386PDQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1504:CP523 RS02630
gene id: 1504:CP523_RS02630
uniprot id: A0A386PDM6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1504:CP523 RS03590
gene id: 1504:CP523_RS03590
uniprot id: A0A386PCC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1504:CP523 RS14920
gene id: 1504:CP523_RS14920
uniprot id: A0A386PHQ6
names: Similarity
messages: Belongs to the UPF0749 family.

1504:CP523 RS07135
gene id: 1504:CP523_RS07135
uniprot id: A0A386PH73
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS09335
gene id: 1504:CP523_RS09335
uniprot id: A0A386PK57
names: Subcellular Location Annotation
messages: Membrane

1504:CP523 RS11155
gene id: 1504:CP523_RS11155
uniprot id: A0A386PGL3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1504:CP523 RS09575
gene id: 1504:CP523_RS09575
uniprot id: A0A386PK92
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1504:CP523 RS08855
gene id: 1504:CP523_RS08855
uniprot id: A0A386PEP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

1504:CP523 RS09150
gene id: 1504:CP523_RS09150
uniprot id: A0A386PIT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1504:CP523 RS02870
gene id: 1504:CP523_RS02870
uniprot id: A0A386PCH7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1504:CP523 RS02030
gene id: 1504:CP523_RS02030
uniprot id: A0A386PBL0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

1504:CP523 RS00285
gene id: 1504:CP523_RS00285
uniprot id: A0A386PEB2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1504:CP523 RS01060
gene id: 1504:CP523_RS01060
uniprot id: A0A386PB46
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1504:CP523 RS01295
gene id: 1504:CP523_RS01295
uniprot id: A0A386PCI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1504:CP523 RS09665
gene id: 1504:CP523_RS09665
uniprot id: A0A386PJ82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

1504:CP523 RS11000
gene id: 1504:CP523_RS11000
uniprot id: A0A386PKS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1504:CP523 RS10525
gene id: 1504:CP523_RS10525
uniprot id: A0A386PHC6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1504:CP523 RS06610
gene id: 1504:CP523_RS06610
uniprot id: A0A386PDS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1504:CP523 RS07970
gene id: 1504:CP523_RS07970
uniprot id: A0A386PJJ3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

1504:CP523 RS03725
gene id: 1504:CP523_RS03725
uniprot id: A0A386PFI4
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1504:CP523 RS14990
gene id: 1504:CP523_RS14990
uniprot id: A0A386PLH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1504:CP523 RS01435
gene id: 1504:CP523_RS01435
uniprot id: A0A386PD10
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1504:CP523 RS14420
gene id: 1504:CP523_RS14420
uniprot id: A0A386PJT1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1504:CP523 RS05230
gene id: 1504:CP523_RS05230
uniprot id: A0A386PH29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1504:CP523 RS05210
gene id: 1504:CP523_RS05210
uniprot id: A0A386PH72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1504:CP523 RS13435
gene id: 1504:CP523_RS13435
uniprot id: A0A386PJC5
names: Similarity
messages: Belongs to the UPF0237 family.