1470434:AZF00 RS08230
gene id: 1470434:AZF00_RS08230
uniprot id: A0A127M521
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

1470434:AZF00 RS16725
gene id: 1470434:AZF00_RS16725
uniprot id: A0A127M9B8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1470434:AZF00 RS00185
gene id: 1470434:AZF00_RS00185
uniprot id: A0A127M0Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

1470434:AZF00 RS16970
gene id: 1470434:AZF00_RS16970
uniprot id: A0A127M9N8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1470434:AZF00 RS04045
gene id: 1470434:AZF00_RS04045
uniprot id: A0A127M2R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

1470434:AZF00 RS02265
gene id: 1470434:AZF00_RS02265
uniprot id: A0A127M1U2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1470434:AZF00 RS08300
gene id: 1470434:AZF00_RS08300
uniprot id: A0A127M4V8
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

1470434:AZF00 RS08425
gene id: 1470434:AZF00_RS08425
uniprot id: A0A127M509
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS15075
gene id: 1470434:AZF00_RS15075
uniprot id: A0A127M8F4
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS09560
gene id: 1470434:AZF00_RS09560
uniprot id: A0A127M5J4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1470434:AZF00 RS18370
gene id: 1470434:AZF00_RS18370
uniprot id: A0A127MAE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

1470434:AZF00 RS03830
gene id: 1470434:AZF00_RS03830
uniprot id: A0A127M2M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

1470434:AZF00 RS00235
gene id: 1470434:AZF00_RS00235
uniprot id: A0A127M0S3
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

1470434:AZF00 RS13400
gene id: 1470434:AZF00_RS13400
uniprot id: A0A127M7T9
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1470434:AZF00 RS04150
gene id: 1470434:AZF00_RS04150
uniprot id: A0A127M2T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS14105
gene id: 1470434:AZF00_RS14105
uniprot id: A0A127M812
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1470434:AZF00 RS06965
gene id: 1470434:AZF00_RS06965
uniprot id: A0A127M486
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1470434:AZF00 RS14585
gene id: 1470434:AZF00_RS14585
uniprot id: A0A127M8B4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS17610
gene id: 1470434:AZF00_RS17610
uniprot id: A0A127M9W9
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1470434:AZF00 RS08510
gene id: 1470434:AZF00_RS08510
uniprot id: A0A127M500
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1470434:AZF00 RS04730
gene id: 1470434:AZF00_RS04730
uniprot id: A0A127M344
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

1470434:AZF00 RS08095
gene id: 1470434:AZF00_RS08095
uniprot id: A0A127M4T1
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1470434:AZF00 RS09565
gene id: 1470434:AZF00_RS09565
uniprot id: A0A127M5K4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

1470434:AZF00 RS01330
gene id: 1470434:AZF00_RS01330
uniprot id: A0A127M1C4
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1470434:AZF00 RS07070
gene id: 1470434:AZF00_RS07070
uniprot id: A0A127M4B0
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1470434:AZF00 RS01715
gene id: 1470434:AZF00_RS01715
uniprot id: A0A127MAH2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1470434:AZF00 RS02940
gene id: 1470434:AZF00_RS02940
uniprot id: A0A127M265
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1470434:AZF00 RS15500
gene id: 1470434:AZF00_RS15500
uniprot id: A0A127M8N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1470434:AZF00 RS03455
gene id: 1470434:AZF00_RS03455
uniprot id: A0A127M2G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1470434:AZF00 RS18670
gene id: 1470434:AZF00_RS18670
uniprot id: A0A127MAC6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1470434:AZF00 RS16560
gene id: 1470434:AZF00_RS16560
uniprot id: A0A127M987
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1470434:AZF00 RS16965
gene id: 1470434:AZF00_RS16965
uniprot id: A0A127M9G7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1470434:AZF00 RS09845
gene id: 1470434:AZF00_RS09845
uniprot id: A0A127MAT0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1470434:AZF00 RS07380
gene id: 1470434:AZF00_RS07380
uniprot id: A0A127M4H5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1470434:AZF00 RS08825
gene id: 1470434:AZF00_RS08825
uniprot id: A0A127M591
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane

1470434:AZF00 RS18380
gene id: 1470434:AZF00_RS18380
uniprot id: A0A127MAA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1470434:AZF00 RS04250
gene id: 1470434:AZF00_RS04250
uniprot id: A0A127M2U9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1470434:AZF00 RS08985
gene id: 1470434:AZF00_RS08985
uniprot id: A0A127MAR3
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS05410
gene id: 1470434:AZF00_RS05410
uniprot id: A0A127M3H2
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.

1470434:AZF00 RS07720
gene id: 1470434:AZF00_RS07720
uniprot id: A0A127M4W1
names: Similarity
messages: Belongs to the UPF0260 family.

1470434:AZF00 RS01595
gene id: 1470434:AZF00_RS01595
uniprot id: A0A127M1H3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS04490
gene id: 1470434:AZF00_RS04490
uniprot id: A0A127M2Y6
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS13700
gene id: 1470434:AZF00_RS13700
uniprot id: A0A127M7T1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1470434:AZF00 RS13895
gene id: 1470434:AZF00_RS13895
uniprot id: A0A127M7W5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS18155
gene id: 1470434:AZF00_RS18155
uniprot id: A0A127MA73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1470434:AZF00 RS00460
gene id: 1470434:AZF00_RS00460
uniprot id: A0A127M0V7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1470434:AZF00 RS11715
gene id: 1470434:AZF00_RS11715
uniprot id: A0A127M6N5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1470434:AZF00 RS17065
gene id: 1470434:AZF00_RS17065
uniprot id: A0A127M9I5
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1470434:AZF00 RS15860
gene id: 1470434:AZF00_RS15860
uniprot id: A0A127M8X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS01965
gene id: 1470434:AZF00_RS01965
uniprot id: A0A127M1Q6
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1470434:AZF00 RS02290
gene id: 1470434:AZF00_RS02290
uniprot id: A0A127M1W9
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1470434:AZF00 RS02495
gene id: 1470434:AZF00_RS02495
uniprot id: A0A127M1Z3
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS11510
gene id: 1470434:AZF00_RS11510
uniprot id: A0A127M6N3
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

1470434:AZF00 RS10790
gene id: 1470434:AZF00_RS10790
uniprot id: A0A127M6C4
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS00690
gene id: 1470434:AZF00_RS00690
uniprot id: A0A127M106
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1470434:AZF00 RS10275
gene id: 1470434:AZF00_RS10275
uniprot id: A0A127M635
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1470434:AZF00 RS17730
gene id: 1470434:AZF00_RS17730
uniprot id: A0A127M9Y9
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1470434:AZF00 RS16845
gene id: 1470434:AZF00_RS16845
uniprot id: A0A127M9I0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1470434:AZF00 RS09545
gene id: 1470434:AZF00_RS09545
uniprot id: A0A127M5L9
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

1470434:AZF00 RS09220
gene id: 1470434:AZF00_RS09220
uniprot id: A0A127M5G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1470434:AZF00 RS03650
gene id: 1470434:AZF00_RS03650
uniprot id: A0A127M2J6
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1470434:AZF00 RS02085
gene id: 1470434:AZF00_RS02085
uniprot id: A0A127M1S5
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1470434:AZF00 RS05305
gene id: 1470434:AZF00_RS05305
uniprot id: A0A127M3C3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1470434:AZF00 RS09210
gene id: 1470434:AZF00_RS09210
uniprot id: A0A127M5F1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1470434:AZF00 RS10255
gene id: 1470434:AZF00_RS10255
uniprot id: A0A127M5W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1470434:AZF00 RS18645
gene id: 1470434:AZF00_RS18645
uniprot id: A0A127MAE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1470434:AZF00 RS14650
gene id: 1470434:AZF00_RS14650
uniprot id: A0A127M8C5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1470434:AZF00 RS08295
gene id: 1470434:AZF00_RS08295
uniprot id: A0A127M4X8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS09500
gene id: 1470434:AZF00_RS09500
uniprot id: A0A127M5Q4
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1470434:AZF00 RS12460
gene id: 1470434:AZF00_RS12460
uniprot id: A0A127M723
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1470434:AZF00 RS07495
gene id: 1470434:AZF00_RS07495
uniprot id: A0A127M4I9
names: Similarity
messages: Belongs to the GSP E family.

1470434:AZF00 RS09610
gene id: 1470434:AZF00_RS09610
uniprot id: A0A127M5R9
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

1470434:AZF00 RS07575
gene id: 1470434:AZF00_RS07575
uniprot id: A0A127M4K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

1470434:AZF00 RS07205
gene id: 1470434:AZF00_RS07205
uniprot id: A0A127M4D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1470434:AZF00 RS13790
gene id: 1470434:AZF00_RS13790
uniprot id: A0A127M7X9
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS13485
gene id: 1470434:AZF00_RS13485
uniprot id: A0A127M7N1
names: Similarity
messages: Belongs to the GSP E family.

1470434:AZF00 RS04525
gene id: 1470434:AZF00_RS04525
uniprot id: A0A127M315
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1470434:AZF00 RS10315
gene id: 1470434:AZF00_RS10315
uniprot id: A0A127M5X3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1470434:AZF00 RS11420
gene id: 1470434:AZF00_RS11420
uniprot id: A0A127M6Q6
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

1470434:AZF00 RS15775
gene id: 1470434:AZF00_RS15775
uniprot id: A0A127M8Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1470434:AZF00 RS06880
gene id: 1470434:AZF00_RS06880
uniprot id: A0A127M4A6
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1470434:AZF00 RS17175
gene id: 1470434:AZF00_RS17175
uniprot id: A0A127M9R7
names: Similarity
messages: Belongs to the RelE toxin family.

1470434:AZF00 RS12195
gene id: 1470434:AZF00_RS12195
uniprot id: A0A127M730
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1470434:AZF00 RS02130
gene id: 1470434:AZF00_RS02130
uniprot id: A0A127M1T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1470434:AZF00 RS18595
gene id: 1470434:AZF00_RS18595
uniprot id: A0A127MAD7
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS06100
gene id: 1470434:AZF00_RS06100
uniprot id: A0A127M3U3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1470434:AZF00 RS07545
gene id: 1470434:AZF00_RS07545
uniprot id: A0A127M4K1
names: Similarity
messages: Belongs to the peptidase A24 family.

1470434:AZF00 RS11970
gene id: 1470434:AZF00_RS11970
uniprot id: A0A127M702
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1470434:AZF00 RS06460
gene id: 1470434:AZF00_RS06460
uniprot id: A0A127M432
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1470434:AZF00 RS01310
gene id: 1470434:AZF00_RS01310
uniprot id: A0A127M1A6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1470434:AZF00 RS00250
gene id: 1470434:AZF00_RS00250
uniprot id: A0A127M0R8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1470434:AZF00 RS16610
gene id: 1470434:AZF00_RS16610
uniprot id: A0A127M9A4
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

1470434:AZF00 RS11355
gene id: 1470434:AZF00_RS11355
uniprot id: A0A127M6J3
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1470434:AZF00 RS01845
gene id: 1470434:AZF00_RS01845
uniprot id: A0A127M1L4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1470434:AZF00 RS15875
gene id: 1470434:AZF00_RS15875
uniprot id: A0A127M916
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1470434:AZF00 RS17940
gene id: 1470434:AZF00_RS17940
uniprot id: A0A127M9Z0
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1470434:AZF00 RS18655
gene id: 1470434:AZF00_RS18655
uniprot id: A0A127MAC2
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS00580
gene id: 1470434:AZF00_RS00580
uniprot id: A0A127M0X6
names: Similarity
messages: Belongs to the CFA/CMAS family.

1470434:AZF00 RS11905
gene id: 1470434:AZF00_RS11905
uniprot id: A0A127M6X0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1470434:AZF00 RS14265
gene id: 1470434:AZF00_RS14265
uniprot id: A0A127M835
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1470434:AZF00 RS15660
gene id: 1470434:AZF00_RS15660
uniprot id: A0A127M8X5
names: Cofactor
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group I subfamily.
messages: Binds 1 heme group per subunit.

1470434:AZF00 RS02250
gene id: 1470434:AZF00_RS02250
uniprot id: A0A127M1U4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1470434:AZF00 RS16320
gene id: 1470434:AZF00_RS16320
uniprot id: A0A127M971
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1470434:AZF00 RS00065
gene id: 1470434:AZF00_RS00065
uniprot id: A0A127M0P0
names: Similarity
messages: Belongs to the pirin family.

1470434:AZF00 RS17675
gene id: 1470434:AZF00_RS17675
uniprot id: A0A127M9W7
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1470434:AZF00 RS14565
gene id: 1470434:AZF00_RS14565
uniprot id: A0A127M8B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

1470434:AZF00 RS09485
gene id: 1470434:AZF00_RS09485
uniprot id: A0A127M5J5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1470434:AZF00 RS04450
gene id: 1470434:AZF00_RS04450
uniprot id: A0A127MAN6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS06225
gene id: 1470434:AZF00_RS06225
uniprot id: A0A127M3T7
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS08640
gene id: 1470434:AZF00_RS08640
uniprot id: A0A127M549
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS10645
gene id: 1470434:AZF00_RS10645
uniprot id: A0A127MAR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

1470434:AZF00 RS17010
gene id: 1470434:AZF00_RS17010
uniprot id: A0A127M9K8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
messages: Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS10860
gene id: 1470434:AZF00_RS10860
uniprot id: A0A127M6C9
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS08325
gene id: 1470434:AZF00_RS08325
uniprot id: A0A127M505
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1470434:AZF00 RS12485
gene id: 1470434:AZF00_RS12485
uniprot id: A0A127M782
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS09265
gene id: 1470434:AZF00_RS09265
uniprot id: A0A127M5I7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1470434:AZF00 RS09960
gene id: 1470434:AZF00_RS09960
uniprot id: A0A127M5T9
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1470434:AZF00 RS07385
gene id: 1470434:AZF00_RS07385
uniprot id: A0A127M4H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1470434:AZF00 RS01265
gene id: 1470434:AZF00_RS01265
uniprot id: A0A127M1A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS14600
gene id: 1470434:AZF00_RS14600
uniprot id: A0A127M883
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1470434:AZF00 RS17165
gene id: 1470434:AZF00_RS17165
uniprot id: A0A127M9J9
names: Similarity
messages: Belongs to the YoeB family.

1470434:AZF00 RS02240
gene id: 1470434:AZF00_RS02240
uniprot id: A0A127M1V7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1470434:AZF00 RS07295
gene id: 1470434:AZF00_RS07295
uniprot id: A0A127M4G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS07225
gene id: 1470434:AZF00_RS07225
uniprot id: A0A127M4F6
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1470434:AZF00 RS11845
gene id: 1470434:AZF00_RS11845
uniprot id: A0A127M6V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1470434:AZF00 RS08285
gene id: 1470434:AZF00_RS08285
uniprot id: A0A127M532
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1470434:AZF00 RS09550
gene id: 1470434:AZF00_RS09550
uniprot id: A0A127M5R1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1470434:AZF00 RS12355
gene id: 1470434:AZF00_RS12355
uniprot id: A0A127M759
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1470434:AZF00 RS05725
gene id: 1470434:AZF00_RS05725
uniprot id: A0A127M3N9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1470434:AZF00 RS02035
gene id: 1470434:AZF00_RS02035
uniprot id: A0A127M1Q2
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

1470434:AZF00 RS01900
gene id: 1470434:AZF00_RS01900
uniprot id: A0A127M1N5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1470434:AZF00 RS14085
gene id: 1470434:AZF00_RS14085
uniprot id: A0A127M7Y5
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS01985
gene id: 1470434:AZF00_RS01985
uniprot id: A0A127M1Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1470434:AZF00 RS17805
gene id: 1470434:AZF00_RS17805
uniprot id: A0A127M9W2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1470434:AZF00 RS05950
gene id: 1470434:AZF00_RS05950
uniprot id: A0A127M3Y8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

1470434:AZF00 RS17975
gene id: 1470434:AZF00_RS17975
uniprot id: A0A127MA03
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1470434:AZF00 RS16410
gene id: 1470434:AZF00_RS16410
uniprot id: A0A127M9A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1470434:AZF00 RS09950
gene id: 1470434:AZF00_RS09950
uniprot id: A0A127M5T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

1470434:AZF00 RS03380
gene id: 1470434:AZF00_RS03380
uniprot id: A0A127M2F4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1470434:AZF00 RS02100
gene id: 1470434:AZF00_RS02100
uniprot id: A0A127M1Q3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1470434:AZF00 RS15630
gene id: 1470434:AZF00_RS15630
uniprot id: A0A127M8T5
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1470434:AZF00 RS12455
gene id: 1470434:AZF00_RS12455
uniprot id: A0A127M742
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1470434:AZF00 RS16555
gene id: 1470434:AZF00_RS16555
uniprot id: A0A127MAY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1470434:AZF00 RS03975
gene id: 1470434:AZF00_RS03975
uniprot id: A0A127M2R0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1470434:AZF00 RS11130
gene id: 1470434:AZF00_RS11130
uniprot id: A0A127M6H2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1470434:AZF00 RS06795
gene id: 1470434:AZF00_RS06795
uniprot id: A0A127M454
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1470434:AZF00 RS03600
gene id: 1470434:AZF00_RS03600
uniprot id: A0A127MAI7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1470434:AZF00 RS07835
gene id: 1470434:AZF00_RS07835
uniprot id: A0A127M4S0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1470434:AZF00 RS05160
gene id: 1470434:AZF00_RS05160
uniprot id: A0A127M3B9
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

1470434:AZF00 RS13930
gene id: 1470434:AZF00_RS13930
uniprot id: A0A127M7V7
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1470434:AZF00 RS14160
gene id: 1470434:AZF00_RS14160
uniprot id: A0A127M814
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS09585
gene id: 1470434:AZF00_RS09585
uniprot id: A0A127M5N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

1470434:AZF00 RS07680
gene id: 1470434:AZF00_RS07680
uniprot id: A0A127M4M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1470434:AZF00 RS12205
gene id: 1470434:AZF00_RS12205
uniprot id: A0A127M705
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1470434:AZF00 RS01935
gene id: 1470434:AZF00_RS01935
uniprot id: A0A127M1P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

1470434:AZF00 RS12020
gene id: 1470434:AZF00_RS12020
uniprot id: A0A127M712
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS15175
gene id: 1470434:AZF00_RS15175
uniprot id: A0A127M8M6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS07245
gene id: 1470434:AZF00_RS07245
uniprot id: A0A127M4J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1470434:AZF00 RS13805
gene id: 1470434:AZF00_RS13805
uniprot id: A0A127M7U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1470434:AZF00 RS13880
gene id: 1470434:AZF00_RS13880
uniprot id: A0A127M7V4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1470434:AZF00 RS15155
gene id: 1470434:AZF00_RS15155
uniprot id: A0A127M8K4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1470434:AZF00 RS07935
gene id: 1470434:AZF00_RS07935
uniprot id: A0A127M4T3
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS15450
gene id: 1470434:AZF00_RS15450
uniprot id: A0A127M8S6
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1470434:AZF00 RS02200
gene id: 1470434:AZF00_RS02200
uniprot id: A0A127M1R2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1470434:AZF00 RS15325
gene id: 1470434:AZF00_RS15325
uniprot id: A0A127M8M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SelU family.
messages: Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
messages: Monomer.

1470434:AZF00 RS06280
gene id: 1470434:AZF00_RS06280
uniprot id: A0A127M3U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1470434:AZF00 RS18045
gene id: 1470434:AZF00_RS18045
uniprot id: A0A127MA89
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1470434:AZF00 RS00070
gene id: 1470434:AZF00_RS00070
uniprot id: A0A127M0N9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1470434:AZF00 RS04195
gene id: 1470434:AZF00_RS04195
uniprot id: A0A127M2T9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1470434:AZF00 RS07470
gene id: 1470434:AZF00_RS07470
uniprot id: A0A127M4I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

1470434:AZF00 RS10720
gene id: 1470434:AZF00_RS10720
uniprot id: A0A127M6A7
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1470434:AZF00 RS12480
gene id: 1470434:AZF00_RS12480
uniprot id: A0A127M757
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1470434:AZF00 RS17970
gene id: 1470434:AZF00_RS17970
uniprot id: A0A127M9Z5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1470434:AZF00 RS06925
gene id: 1470434:AZF00_RS06925
uniprot id: A0A127M490
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1470434:AZF00 RS04420
gene id: 1470434:AZF00_RS04420
uniprot id: A0A127MAK2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1470434:AZF00 RS01060
gene id: 1470434:AZF00_RS01060
uniprot id: A0A127MAJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1470434:AZF00 RS09520
gene id: 1470434:AZF00_RS09520
uniprot id: A0A127M5M4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1470434:AZF00 RS00205
gene id: 1470434:AZF00_RS00205
uniprot id: A0A127M0Q4
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.

1470434:AZF00 RS04080
gene id: 1470434:AZF00_RS04080
uniprot id: A0A127M2S7
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS08355
gene id: 1470434:AZF00_RS08355
uniprot id: A0A127M4W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

1470434:AZF00 RS10535
gene id: 1470434:AZF00_RS10535
uniprot id: A0A127M673
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS12070
gene id: 1470434:AZF00_RS12070
uniprot id: A0A127M725
names: Similarity
messages: Belongs to the pyruvate kinase family.

1470434:AZF00 RS03480
gene id: 1470434:AZF00_RS03480
uniprot id: A0A127M2G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1470434:AZF00 RS12950
gene id: 1470434:AZF00_RS12950
uniprot id: A0A127M7G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS02170
gene id: 1470434:AZF00_RS02170
uniprot id: A0A127M1R9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1470434:AZF00 RS14525
gene id: 1470434:AZF00_RS14525
uniprot id: A0A127M877
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1470434:AZF00 RS12380
gene id: 1470434:AZF00_RS12380
uniprot id: A0A127M778
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

1470434:AZF00 RS00985
gene id: 1470434:AZF00_RS00985
uniprot id: A0A127M160
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1470434:AZF00 RS06575
gene id: 1470434:AZF00_RS06575
uniprot id: A0A127M421
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1470434:AZF00 RS02210
gene id: 1470434:AZF00_RS02210
uniprot id: A0A127M1T2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1470434:AZF00 RS10510
gene id: 1470434:AZF00_RS10510
uniprot id: A0A127M674
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1470434:AZF00 RS11520
gene id: 1470434:AZF00_RS11520
uniprot id: A0A127M6M7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1470434:AZF00 RS05705
gene id: 1470434:AZF00_RS05705
uniprot id: A0A127M3P3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1470434:AZF00 RS14530
gene id: 1470434:AZF00_RS14530
uniprot id: A0A127M8C2
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1470434:AZF00 RS01335
gene id: 1470434:AZF00_RS01335
uniprot id: A0A127M1D3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1470434:AZF00 RS10895
gene id: 1470434:AZF00_RS10895
uniprot id: A0A127M6B3
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1470434:AZF00 RS17425
gene id: 1470434:AZF00_RS17425
uniprot id: A0A127M9Q3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1470434:AZF00 RS03665
gene id: 1470434:AZF00_RS03665
uniprot id: A0A127M2J3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1470434:AZF00 RS08170
gene id: 1470434:AZF00_RS08170
uniprot id: A0A127M4X3
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

1470434:AZF00 RS17205
gene id: 1470434:AZF00_RS17205
uniprot id: A0A127M9K4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1470434:AZF00 RS14625
gene id: 1470434:AZF00_RS14625
uniprot id: A0A127M8C0
names: Similarity
messages: Belongs to the UPF0102 family.

1470434:AZF00 RS01200
gene id: 1470434:AZF00_RS01200
uniprot id: A0A127M198
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TraY family.
messages: Cytoplasm

1470434:AZF00 RS14815
gene id: 1470434:AZF00_RS14815
uniprot id: A0A127M8G6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1470434:AZF00 RS12440
gene id: 1470434:AZF00_RS12440
uniprot id: A0A127MAT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1470434:AZF00 RS01275
gene id: 1470434:AZF00_RS01275
uniprot id: A0A127M1B5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1470434:AZF00 RS04030
gene id: 1470434:AZF00_RS04030
uniprot id: A0A127M2R9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1470434:AZF00 RS16160
gene id: 1470434:AZF00_RS16160
uniprot id: A0A127M968
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P-Pant transferase superfamily. EntD family.
messages: EntB, EntD, EntE, and EntF form a multienzyme complex called enterobactin synthase.
messages: Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo-domains of both EntB (ArCP domain) and EntF (PCP domain) to yield their holo-forms which make them competent for the activation of 2,3-dihydroxybenzoate (DHB) and L-serine, respectively.

1470434:AZF00 RS00135
gene id: 1470434:AZF00_RS00135
uniprot id: A0A127M0P4
names: Similarity
messages: Belongs to the SCO1/2 family.

1470434:AZF00 RS11490
gene id: 1470434:AZF00_RS11490
uniprot id: A0A127M6K6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

1470434:AZF00 RS11270
gene id: 1470434:AZF00_RS11270
uniprot id: A0A127M6I1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1470434:AZF00 RS15575
gene id: 1470434:AZF00_RS15575
uniprot id: A0A127M8X1
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS05600
gene id: 1470434:AZF00_RS05600
uniprot id: A0A127M3I3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS09940
gene id: 1470434:AZF00_RS09940
uniprot id: A0A127M5U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1470434:AZF00 RS07190
gene id: 1470434:AZF00_RS07190
uniprot id: A0A127MAV2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1470434:AZF00 RS07695
gene id: 1470434:AZF00_RS07695
uniprot id: A0A127M4T8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1470434:AZF00 RS05115
gene id: 1470434:AZF00_RS05115
uniprot id: A0A127M3E2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1470434:AZF00 RS11365
gene id: 1470434:AZF00_RS11365
uniprot id: A0A127M6M4
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 104 family.
messages: Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes.

1470434:AZF00 RS11080
gene id: 1470434:AZF00_RS11080
uniprot id: A0A127M6D5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1470434:AZF00 RS16765
gene id: 1470434:AZF00_RS16765
uniprot id: A0A127M9F1
names: Similarity
messages: Belongs to the pirin family.

1470434:AZF00 RS05430
gene id: 1470434:AZF00_RS05430
uniprot id: A0A127M3G5
names: Similarity
messages: Belongs to the CobH/CbiC family.

1470434:AZF00 RS16235
gene id: 1470434:AZF00_RS16235
uniprot id: A0A127M942
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1470434:AZF00 RS00230
gene id: 1470434:AZF00_RS00230
uniprot id: A0A127M0R1
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

1470434:AZF00 RS06600
gene id: 1470434:AZF00_RS06600
uniprot id: A0A127M413
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1470434:AZF00 RS02145
gene id: 1470434:AZF00_RS02145
uniprot id: A0A127M1S6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1470434:AZF00 RS14195
gene id: 1470434:AZF00_RS14195
uniprot id: A0A127M808
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1470434:AZF00 RS00710
gene id: 1470434:AZF00_RS00710
uniprot id: A0A127M119
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1470434:AZF00 RS07210
gene id: 1470434:AZF00_RS07210
uniprot id: A0A127M4D9
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1470434:AZF00 RS09895
gene id: 1470434:AZF00_RS09895
uniprot id: A0A127M5S0
names: Subcellular Location Annotation
messages: nucleolus

1470434:AZF00 RS09145
gene id: 1470434:AZF00_RS09145
uniprot id: A0A127M5E6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1470434:AZF00 RS11390
gene id: 1470434:AZF00_RS11390
uniprot id: A0A127M6K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1470434:AZF00 RS08210
gene id: 1470434:AZF00_RS08210
uniprot id: A0A127M4Z6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1470434:AZF00 RS11840
gene id: 1470434:AZF00_RS11840
uniprot id: A0A127M6X1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1470434:AZF00 RS06785
gene id: 1470434:AZF00_RS06785
uniprot id: A0A127M469
names: Similarity
messages: Belongs to the CvfB family.

1470434:AZF00 RS06095
gene id: 1470434:AZF00_RS06095
uniprot id: A0A127M3T1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1470434:AZF00 RS03370
gene id: 1470434:AZF00_RS03370
uniprot id: A0A127M2F0
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1470434:AZF00 RS07165
gene id: 1470434:AZF00_RS07165
uniprot id: A0A127M4E7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1470434:AZF00 RS00825
gene id: 1470434:AZF00_RS00825
uniprot id: A0A127M138
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1470434:AZF00 RS07060
gene id: 1470434:AZF00_RS07060
uniprot id: A0A127M4B6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1470434:AZF00 RS14540
gene id: 1470434:AZF00_RS14540
uniprot id: A0A127M876
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1470434:AZF00 RS04410
gene id: 1470434:AZF00_RS04410
uniprot id: A0A127M2Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1470434:AZF00 RS03460
gene id: 1470434:AZF00_RS03460
uniprot id: A0A127M2F5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1470434:AZF00 RS05855
gene id: 1470434:AZF00_RS05855
uniprot id: A0A127M3S1
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS12230
gene id: 1470434:AZF00_RS12230
uniprot id: A0A127M728
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1470434:AZF00 RS14690
gene id: 1470434:AZF00_RS14690
uniprot id: A0A127M881
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1470434:AZF00 RS16930
gene id: 1470434:AZF00_RS16930
uniprot id: A0A127M9I2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1470434:AZF00 RS14520
gene id: 1470434:AZF00_RS14520
uniprot id: A0A127M853
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1470434:AZF00 RS07200
gene id: 1470434:AZF00_RS07200
uniprot id: A0A127M4E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1470434:AZF00 RS18170
gene id: 1470434:AZF00_RS18170
uniprot id: A0A127MA57
names: Similarity
messages: Belongs to the UPF0246 family.

1470434:AZF00 RS16185
gene id: 1470434:AZF00_RS16185
uniprot id: A0A127M905
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1470434:AZF00 RS02195
gene id: 1470434:AZF00_RS02195
uniprot id: A0A127M1T6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1470434:AZF00 RS09115
gene id: 1470434:AZF00_RS09115
uniprot id: A0A127M5C7
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

1470434:AZF00 RS00125
gene id: 1470434:AZF00_RS00125
uniprot id: A0A127M0P7
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS03585
gene id: 1470434:AZF00_RS03585
uniprot id: A0A127M2I1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1470434:AZF00 RS13175
gene id: 1470434:AZF00_RS13175
uniprot id: A0A127M7K5
names: Similarity
messages: Belongs to the Dps family.

1470434:AZF00 RS04100
gene id: 1470434:AZF00_RS04100
uniprot id: A0A127M2S8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1470434:AZF00 RS12170
gene id: 1470434:AZF00_RS12170
uniprot id: A0A127M717
names: Similarity
messages: Belongs to the DapA family.

1470434:AZF00 RS11195
gene id: 1470434:AZF00_RS11195
uniprot id: A0A127M6H4
names: Subcellular Location Annotation
messages: Cytoplasm

1470434:AZF00 RS04560
gene id: 1470434:AZF00_RS04560
uniprot id: A0A127M313
names: Similarity
messages: Belongs to the UPF0229 family.

1470434:AZF00 RS12490
gene id: 1470434:AZF00_RS12490
uniprot id: A0A127M756
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS07895
gene id: 1470434:AZF00_RS07895
uniprot id: A0A127M4Q9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

1470434:AZF00 RS05395
gene id: 1470434:AZF00_RS05395
uniprot id: A0A127M3G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS14595
gene id: 1470434:AZF00_RS14595
uniprot id: A0A127M8H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1470434:AZF00 RS11915
gene id: 1470434:AZF00_RS11915
uniprot id: A0A127M6V9
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1470434:AZF00 RS14660
gene id: 1470434:AZF00_RS14660
uniprot id: A0A127M8I3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1470434:AZF00 RS16755
gene id: 1470434:AZF00_RS16755
uniprot id: A0A127M9J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1470434:AZF00 RS01550
gene id: 1470434:AZF00_RS01550
uniprot id: A0A127M1H4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1470434:AZF00 RS15275
gene id: 1470434:AZF00_RS15275
uniprot id: A0A127M8J1
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS14345
gene id: 1470434:AZF00_RS14345
uniprot id: A0A127M872
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1470434:AZF00 RS18435
gene id: 1470434:AZF00_RS18435
uniprot id: A0A127MAA7
names: Function
messages: Catalyzes the oxidation of D-lactate to pyruvate.

1470434:AZF00 RS01505
gene id: 1470434:AZF00_RS01505
uniprot id: A0A127M1E6
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

1470434:AZF00 RS09480
gene id: 1470434:AZF00_RS09480
uniprot id: A0A127M5M1
names: Similarity
messages: Belongs to the GcvT family.

1470434:AZF00 RS03435
gene id: 1470434:AZF00_RS03435
uniprot id: A0A127M2H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1470434:AZF00 RS09810
gene id: 1470434:AZF00_RS09810
uniprot id: A0A127M5R6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1470434:AZF00 RS10750
gene id: 1470434:AZF00_RS10750
uniprot id: A0A127M656
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1470434:AZF00 RS03285
gene id: 1470434:AZF00_RS03285
uniprot id: A0A127M2E0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1470434:AZF00 RS15485
gene id: 1470434:AZF00_RS15485
uniprot id: A0A127M8N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS00630
gene id: 1470434:AZF00_RS00630
uniprot id: A0A127M0Y7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1470434:AZF00 RS13015
gene id: 1470434:AZF00_RS13015
uniprot id: A0A127M7H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS02150
gene id: 1470434:AZF00_RS02150
uniprot id: A0A127M1Q0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1470434:AZF00 RS14975
gene id: 1470434:AZF00_RS14975
uniprot id: A0A127M8G4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1470434:AZF00 RS04825
gene id: 1470434:AZF00_RS04825
uniprot id: A0A127M374
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS15895
gene id: 1470434:AZF00_RS15895
uniprot id: A0A127M8Z0
names: Similarity
messages: Belongs to the histone deacetylase family.

1470434:AZF00 RS16255
gene id: 1470434:AZF00_RS16255
uniprot id: A0A127M973
names: Similarity
messages: Belongs to the UPF0178 family.

1470434:AZF00 RS15095
gene id: 1470434:AZF00_RS15095
uniprot id: A0A127M8I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1470434:AZF00 RS16855
gene id: 1470434:AZF00_RS16855
uniprot id: A0A127M9E3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1470434:AZF00 RS10175
gene id: 1470434:AZF00_RS10175
uniprot id: A0A127M5X0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1470434:AZF00 RS02235
gene id: 1470434:AZF00_RS02235
uniprot id: A0A127MAQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1470434:AZF00 RS14440
gene id: 1470434:AZF00_RS14440
uniprot id: A0A127M858
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1470434:AZF00 RS16590
gene id: 1470434:AZF00_RS16590
uniprot id: A0A127M9G6
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1470434:AZF00 RS06315
gene id: 1470434:AZF00_RS06315
uniprot id: A0A127M450
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1470434:AZF00 RS14250
gene id: 1470434:AZF00_RS14250
uniprot id: A0A127M819
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1470434:AZF00 RS12410
gene id: 1470434:AZF00_RS12410
uniprot id: A0A127M749
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1470434:AZF00 RS09770
gene id: 1470434:AZF00_RS09770
uniprot id: A0A127M5V1
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1470434:AZF00 RS03360
gene id: 1470434:AZF00_RS03360
uniprot id: A0A127M2F2
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS13300
gene id: 1470434:AZF00_RS13300
uniprot id: A0A127M7K6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1470434:AZF00 RS18055
gene id: 1470434:AZF00_RS18055
uniprot id: A0A127MA38
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1470434:AZF00 RS02635
gene id: 1470434:AZF00_RS02635
uniprot id: A0A127M208
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1470434:AZF00 RS12615
gene id: 1470434:AZF00_RS12615
uniprot id: A0A127M769
names: Similarity
messages: Belongs to the GST superfamily.

1470434:AZF00 RS15640
gene id: 1470434:AZF00_RS15640
uniprot id: A0A127M8S3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1470434:AZF00 RS11215
gene id: 1470434:AZF00_RS11215
uniprot id: A0A127M6G9
names: Similarity
messages: Belongs to the SUI1 family.

1470434:AZF00 RS14770
gene id: 1470434:AZF00_RS14770
uniprot id: A0A127M8B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1470434:AZF00 RS12405
gene id: 1470434:AZF00_RS12405
uniprot id: A0A127M768
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1470434:AZF00 RS08330
gene id: 1470434:AZF00_RS08330
uniprot id: A0A127M4Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1470434:AZF00 RS13480
gene id: 1470434:AZF00_RS13480
uniprot id: A0A127M7N2
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS07330
gene id: 1470434:AZF00_RS07330
uniprot id: A0A127M4F0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1470434:AZF00 RS08370
gene id: 1470434:AZF00_RS08370
uniprot id: A0A127M527
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS02125
gene id: 1470434:AZF00_RS02125
uniprot id: A0A127M1Q4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1470434:AZF00 RS01300
gene id: 1470434:AZF00_RS01300
uniprot id: A0A127M1C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

1470434:AZF00 RS11385
gene id: 1470434:AZF00_RS11385
uniprot id: A0A127M6N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1470434:AZF00 RS18505
gene id: 1470434:AZF00_RS18505
uniprot id: A0A127MAA3
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1470434:AZF00 RS05325
gene id: 1470434:AZF00_RS05325
uniprot id: A0A127M3H8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1470434:AZF00 RS14645
gene id: 1470434:AZF00_RS14645
uniprot id: A0A127M8E3
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

1470434:AZF00 RS06055
gene id: 1470434:AZF00_RS06055
uniprot id: A0A127M407
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS17690
gene id: 1470434:AZF00_RS17690
uniprot id: A0A127MB79
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1470434:AZF00 RS05590
gene id: 1470434:AZF00_RS05590
uniprot id: A0A127M3L0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1470434:AZF00 RS05680
gene id: 1470434:AZF00_RS05680
uniprot id: A0A127M3K2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

1470434:AZF00 RS05335
gene id: 1470434:AZF00_RS05335
uniprot id: A0A127M3D8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1470434:AZF00 RS09820
gene id: 1470434:AZF00_RS09820
uniprot id: A0A127M5W1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1470434:AZF00 RS12185
gene id: 1470434:AZF00_RS12185
uniprot id: A0A127M6X5
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1470434:AZF00 RS03425
gene id: 1470434:AZF00_RS03425
uniprot id: A0A127M2F7
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1470434:AZF00 RS17390
gene id: 1470434:AZF00_RS17390
uniprot id: A0A127M9T0
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1470434:AZF00 RS00150
gene id: 1470434:AZF00_RS00150
uniprot id: A0A127M0Q7
names: Similarity
messages: Belongs to the Fur family.

1470434:AZF00 RS18775
gene id: 1470434:AZF00_RS18775
uniprot id: A0A127MAE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1470434:AZF00 RS00830
gene id: 1470434:AZF00_RS00830
uniprot id: A0A127M128
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1470434:AZF00 RS16505
gene id: 1470434:AZF00_RS16505
uniprot id: A0A127M978
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1470434:AZF00 RS05105
gene id: 1470434:AZF00_RS05105
uniprot id: A0A127M3C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1470434:AZF00 RS00700
gene id: 1470434:AZF00_RS00700
uniprot id: A0A127M121
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

1470434:AZF00 RS13695
gene id: 1470434:AZF00_RS13695
uniprot id: A0A127M7Q9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1470434:AZF00 RS05805
gene id: 1470434:AZF00_RS05805
uniprot id: A0A127M3Q6
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

1470434:AZF00 RS04570
gene id: 1470434:AZF00_RS04570
uniprot id: A0A127M318
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1470434:AZF00 RS13715
gene id: 1470434:AZF00_RS13715
uniprot id: A0A127M7T4
names: Function
names: Miscellaneous
names: Similarity
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.

1470434:AZF00 RS05610
gene id: 1470434:AZF00_RS05610
uniprot id: A0A127M3L3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1470434:AZF00 RS01190
gene id: 1470434:AZF00_RS01190
uniprot id: A0A127M182
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1470434:AZF00 RS08365
gene id: 1470434:AZF00_RS08365
uniprot id: A0A127M583
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1470434:AZF00 RS07010
gene id: 1470434:AZF00_RS07010
uniprot id: A0A127M4B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1470434:AZF00 RS04835
gene id: 1470434:AZF00_RS04835
uniprot id: A0A127M375
names: Similarity
messages: Belongs to the cytochrome P450 family.

1470434:AZF00 RS13795
gene id: 1470434:AZF00_RS13795
uniprot id: A0A127M7T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Membrane

1470434:AZF00 RS16205
gene id: 1470434:AZF00_RS16205
uniprot id: A0A127M925
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1470434:AZF00 RS05455
gene id: 1470434:AZF00_RS05455
uniprot id: A0A127M3I9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1470434:AZF00 RS01925
gene id: 1470434:AZF00_RS01925
uniprot id: A0A127M1Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1470434:AZF00 RS17470
gene id: 1470434:AZF00_RS17470
uniprot id: A0A127M9S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

1470434:AZF00 RS06960
gene id: 1470434:AZF00_RS06960
uniprot id: A0A127M497
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS13595
gene id: 1470434:AZF00_RS13595
uniprot id: A0A127M7U0
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1470434:AZF00 RS11300
gene id: 1470434:AZF00_RS11300
uniprot id: A0A127M6I8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1470434:AZF00 RS12200
gene id: 1470434:AZF00_RS12200
uniprot id: A0A127M724
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1470434:AZF00 RS09215
gene id: 1470434:AZF00_RS09215
uniprot id: A0A127MAP6
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1470434:AZF00 RS10240
gene id: 1470434:AZF00_RS10240
uniprot id: A0A127M616
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1470434:AZF00 RS16065
gene id: 1470434:AZF00_RS16065
uniprot id: A0A127M8Z8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

1470434:AZF00 RS14875
gene id: 1470434:AZF00_RS14875
uniprot id: A0A127M8B9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1470434:AZF00 RS09765
gene id: 1470434:AZF00_RS09765
uniprot id: A0A127M5U1
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

1470434:AZF00 RS13330
gene id: 1470434:AZF00_RS13330
uniprot id: A0A127M7N3
names: Similarity
messages: Belongs to the WrbA family.

1470434:AZF00 RS05880
gene id: 1470434:AZF00_RS05880
uniprot id: A0A127M3N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1470434:AZF00 RS06360
gene id: 1470434:AZF00_RS06360
uniprot id: A0A127MAM1
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1470434:AZF00 RS00170
gene id: 1470434:AZF00_RS00170
uniprot id: A0A127MAH5
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1470434:AZF00 RS15680
gene id: 1470434:AZF00_RS15680
uniprot id: A0A127M8U5
names: Similarity
messages: In the C-terminal section; belongs to the glutathionylspermidine synthase preATP-grasp family.

1470434:AZF00 RS07360
gene id: 1470434:AZF00_RS07360
uniprot id: A0A127M4H3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1470434:AZF00 RS15140
gene id: 1470434:AZF00_RS15140
uniprot id: A0A127MAX8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1470434:AZF00 RS16760
gene id: 1470434:AZF00_RS16760
uniprot id: A0A127M9E6
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1470434:AZF00 RS15220
gene id: 1470434:AZF00_RS15220
uniprot id: A0A127M8G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1470434:AZF00 RS03535
gene id: 1470434:AZF00_RS03535
uniprot id: A0A127M2G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1470434:AZF00 RS07455
gene id: 1470434:AZF00_RS07455
uniprot id: A0A127M4I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1470434:AZF00 RS00665
gene id: 1470434:AZF00_RS00665
uniprot id: A0A127M0Z8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

1470434:AZF00 RS15045
gene id: 1470434:AZF00_RS15045
uniprot id: A0A127M8H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

1470434:AZF00 RS12955
gene id: 1470434:AZF00_RS12955
uniprot id: A0A127M7E2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1470434:AZF00 RS10850
gene id: 1470434:AZF00_RS10850
uniprot id: A0A127M676
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1470434:AZF00 RS17285
gene id: 1470434:AZF00_RS17285
uniprot id: A0A127M9Q6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1470434:AZF00 RS14320
gene id: 1470434:AZF00_RS14320
uniprot id: A0A127M845
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

1470434:AZF00 RS19605
gene id: 1470434:AZF00_RS19605
uniprot id: A0A127M6A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1470434:AZF00 RS11160
gene id: 1470434:AZF00_RS11160
uniprot id: A0A127M6F7
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS12520
gene id: 1470434:AZF00_RS12520
uniprot id: A0A127M788
names: Similarity
messages: Belongs to the ArsC family.

1470434:AZF00 RS14800
gene id: 1470434:AZF00_RS14800
uniprot id: A0A127M8B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

1470434:AZF00 RS01625
gene id: 1470434:AZF00_RS01625
uniprot id: A0A127M1G0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1470434:AZF00 RS18580
gene id: 1470434:AZF00_RS18580
uniprot id: A0A127MAE8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1470434:AZF00 RS13670
gene id: 1470434:AZF00_RS13670
uniprot id: A0A127M7R6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1470434:AZF00 RS17625
gene id: 1470434:AZF00_RS17625
uniprot id: A0A127M9V7
names: Similarity
messages: Belongs to the UPF0111 family.

1470434:AZF00 RS14870
gene id: 1470434:AZF00_RS14870
uniprot id: A0A127M8H1
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1470434:AZF00 RS00115
gene id: 1470434:AZF00_RS00115
uniprot id: A0A127M0Q1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS03195
gene id: 1470434:AZF00_RS03195
uniprot id: A0A127M2C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1470434:AZF00 RS05935
gene id: 1470434:AZF00_RS05935
uniprot id: A0A127MAP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1470434:AZF00 RS02000
gene id: 1470434:AZF00_RS02000
uniprot id: A0A127M1Q5
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS11545
gene id: 1470434:AZF00_RS11545
uniprot id: A0A127MAS8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1470434:AZF00 RS09225
gene id: 1470434:AZF00_RS09225
uniprot id: A0A127M5E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1470434:AZF00 RS02185
gene id: 1470434:AZF00_RS02185
uniprot id: A0A127M1U7
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1470434:AZF00 RS00085
gene id: 1470434:AZF00_RS00085
uniprot id: A0A127M0N6
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS12255
gene id: 1470434:AZF00_RS12255
uniprot id: A0A127M718
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1470434:AZF00 RS18150
gene id: 1470434:AZF00_RS18150
uniprot id: A0A127MB75
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1470434:AZF00 RS14590
gene id: 1470434:AZF00_RS14590
uniprot id: A0A127M880
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

1470434:AZF00 RS13885
gene id: 1470434:AZF00_RS13885
uniprot id: A0A127M7Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1470434:AZF00 RS03445
gene id: 1470434:AZF00_RS03445
uniprot id: A0A127M2F6
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1470434:AZF00 RS14380
gene id: 1470434:AZF00_RS14380
uniprot id: A0A127M852
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1470434:AZF00 RS13045
gene id: 1470434:AZF00_RS13045
uniprot id: A0A127M7G1
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS15030
gene id: 1470434:AZF00_RS15030
uniprot id: A0A127M8F1
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1470434:AZF00 RS17700
gene id: 1470434:AZF00_RS17700
uniprot id: A0A127MB30
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS02080
gene id: 1470434:AZF00_RS02080
uniprot id: A0A127MAK5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS14445
gene id: 1470434:AZF00_RS14445
uniprot id: A0A127M8F6
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1470434:AZF00 RS03470
gene id: 1470434:AZF00_RS03470
uniprot id: A0A127MAI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1470434:AZF00 RS11305
gene id: 1470434:AZF00_RS11305
uniprot id: A0A127M6I2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1470434:AZF00 RS10030
gene id: 1470434:AZF00_RS10030
uniprot id: A0A127M5W6
names: Similarity
messages: Belongs to the YciI family.

1470434:AZF00 RS13635
gene id: 1470434:AZF00_RS13635
uniprot id: A0A127M7Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1470434:AZF00 RS07290
gene id: 1470434:AZF00_RS07290
uniprot id: A0A127M4G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1470434:AZF00 RS09680
gene id: 1470434:AZF00_RS09680
uniprot id: A0A127M5T0
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1470434:AZF00 RS14910
gene id: 1470434:AZF00_RS14910
uniprot id: A0A127M8H7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1470434:AZF00 RS10470
gene id: 1470434:AZF00_RS10470
uniprot id: A0A127M601
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

1470434:AZF00 RS18295
gene id: 1470434:AZF00_RS18295
uniprot id: A0A127MA56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1470434:AZF00 RS17230
gene id: 1470434:AZF00_RS17230
uniprot id: A0A127M9P6
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1470434:AZF00 RS07105
gene id: 1470434:AZF00_RS07105
uniprot id: A0A127M4D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1470434:AZF00 RS02340
gene id: 1470434:AZF00_RS02340
uniprot id: A0A127M1W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1470434:AZF00 RS12640
gene id: 1470434:AZF00_RS12640
uniprot id: A0A127M784
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS09600
gene id: 1470434:AZF00_RS09600
uniprot id: A0A127M5M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

1470434:AZF00 RS17810
gene id: 1470434:AZF00_RS17810
uniprot id: A0A127M9X2
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

1470434:AZF00 RS07480
gene id: 1470434:AZF00_RS07480
uniprot id: A0A127M4J5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1470434:AZF00 RS05665
gene id: 1470434:AZF00_RS05665
uniprot id: A0A127M3N2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1470434:AZF00 RS07400
gene id: 1470434:AZF00_RS07400
uniprot id: A0A127M4M3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1470434:AZF00 RS01065
gene id: 1470434:AZF00_RS01065
uniprot id: A0A127M164
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BexD/CtrA/VexA family.
messages: Cell outer membrane
messages: Membrane

1470434:AZF00 RS09735
gene id: 1470434:AZF00_RS09735
uniprot id: A0A127M5P6
names: Similarity
messages: Belongs to the UPF0045 family.

1470434:AZF00 RS16200
gene id: 1470434:AZF00_RS16200
uniprot id: A0A127M962
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1470434:AZF00 RS04665
gene id: 1470434:AZF00_RS04665
uniprot id: A0A127M311
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1470434:AZF00 RS02005
gene id: 1470434:AZF00_RS02005
uniprot id: A0A127M1P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1470434:AZF00 RS12065
gene id: 1470434:AZF00_RS12065
uniprot id: A0A127M6Z7
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS07365
gene id: 1470434:AZF00_RS07365
uniprot id: A0A127M4G5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1470434:AZF00 RS03985
gene id: 1470434:AZF00_RS03985
uniprot id: A0A127M2Q8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1470434:AZF00 RS14970
gene id: 1470434:AZF00_RS14970
uniprot id: A0A127M8H0
names: Similarity
messages: Belongs to the PhoH family.

1470434:AZF00 RS03820
gene id: 1470434:AZF00_RS03820
uniprot id: A0A127M2M9
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1470434:AZF00 RS09525
gene id: 1470434:AZF00_RS09525
uniprot id: A0A127M5R5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1470434:AZF00 RS16840
gene id: 1470434:AZF00_RS16840
uniprot id: A0A127M9L1
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

1470434:AZF00 RS05710
gene id: 1470434:AZF00_RS05710
uniprot id: A0A127M3J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1470434:AZF00 RS17370
gene id: 1470434:AZF00_RS17370
uniprot id: A0A127M9P3
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1470434:AZF00 RS03045
gene id: 1470434:AZF00_RS03045
uniprot id: A0A127M285
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1470434:AZF00 RS04945
gene id: 1470434:AZF00_RS04945
uniprot id: A0A127MAK7
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

1470434:AZF00 RS04135
gene id: 1470434:AZF00_RS04135
uniprot id: A0A127M2U1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1470434:AZF00 RS04965
gene id: 1470434:AZF00_RS04965
uniprot id: A0A127M376
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1470434:AZF00 RS11425
gene id: 1470434:AZF00_RS11425
uniprot id: A0A127M6M8
names: Caution
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS16475
gene id: 1470434:AZF00_RS16475
uniprot id: A0A127M9E7
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1470434:AZF00 RS04125
gene id: 1470434:AZF00_RS04125
uniprot id: A0A127M2S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS11630
gene id: 1470434:AZF00_RS11630
uniprot id: A0A127M6Q1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1470434:AZF00 RS03640
gene id: 1470434:AZF00_RS03640
uniprot id: A0A127M2K0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1470434:AZF00 RS10410
gene id: 1470434:AZF00_RS10410
uniprot id: A0A127M5Z1
names: Similarity
messages: Belongs to the AHA1 family.

1470434:AZF00 RS05100
gene id: 1470434:AZF00_RS05100
uniprot id: A0A127M3B0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1470434:AZF00 RS14555
gene id: 1470434:AZF00_RS14555
uniprot id: A0A127M897
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1470434:AZF00 RS14145
gene id: 1470434:AZF00_RS14145
uniprot id: A0A127M7Z9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1470434:AZF00 RS12765
gene id: 1470434:AZF00_RS12765
uniprot id: A0A127M7E5
names: Similarity
messages: Belongs to the cytochrome P450 family.

1470434:AZF00 RS10655
gene id: 1470434:AZF00_RS10655
uniprot id: A0A127MAR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1470434:AZF00 RS15165
gene id: 1470434:AZF00_RS15165
uniprot id: A0A127M8G3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1470434:AZF00 RS02950
gene id: 1470434:AZF00_RS02950
uniprot id: A0A127M269
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1470434:AZF00 RS10715
gene id: 1470434:AZF00_RS10715
uniprot id: A0A127M696
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

1470434:AZF00 RS06510
gene id: 1470434:AZF00_RS06510
uniprot id: A0A127M427
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1470434:AZF00 RS08865
gene id: 1470434:AZF00_RS08865
uniprot id: A0A127MAS7
names: Similarity
messages: Belongs to the FrmR/RcnR family.

1470434:AZF00 RS14140
gene id: 1470434:AZF00_RS14140
uniprot id: A0A127M7Z4
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1470434:AZF00 RS08055
gene id: 1470434:AZF00_RS08055
uniprot id: A0A127M520
names: Similarity
messages: Belongs to the PhzF family.

1470434:AZF00 RS15395
gene id: 1470434:AZF00_RS15395
uniprot id: A0A127M8T0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1470434:AZF00 RS09755
gene id: 1470434:AZF00_RS09755
uniprot id: A0A127M5P0
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS06570
gene id: 1470434:AZF00_RS06570
uniprot id: A0A127M414
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

1470434:AZF00 RS05960
gene id: 1470434:AZF00_RS05960
uniprot id: A0A127M3U0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1470434:AZF00 RS17800
gene id: 1470434:AZF00_RS17800
uniprot id: A0A127M9Y8
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS11190
gene id: 1470434:AZF00_RS11190
uniprot id: A0A127M6F5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1470434:AZF00 RS15510
gene id: 1470434:AZF00_RS15510
uniprot id: A0A127M8T7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1470434:AZF00 RS16220
gene id: 1470434:AZF00_RS16220
uniprot id: A0A127M946
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1470434:AZF00 RS16630
gene id: 1470434:AZF00_RS16630
uniprot id: A0A127M9G0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1470434:AZF00 RS14920
gene id: 1470434:AZF00_RS14920
uniprot id: A0A127M8D3
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1470434:AZF00 RS00320
gene id: 1470434:AZF00_RS00320
uniprot id: A0A127MAF3
names: Similarity
messages: Belongs to the Gfa family.

1470434:AZF00 RS10635
gene id: 1470434:AZF00_RS10635
uniprot id: A0A127M637
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

1470434:AZF00 RS17705
gene id: 1470434:AZF00_RS17705
uniprot id: A0A127M9V6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1470434:AZF00 RS17965
gene id: 1470434:AZF00_RS17965
uniprot id: A0A127MA00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1470434:AZF00 RS15770
gene id: 1470434:AZF00_RS15770
uniprot id: A0A127M901
names: Similarity
messages: Belongs to the MotB family.

1470434:AZF00 RS08090
gene id: 1470434:AZF00_RS08090
uniprot id: A0A127M4U3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1470434:AZF00 RS18100
gene id: 1470434:AZF00_RS18100
uniprot id: A0A127MAA1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1470434:AZF00 RS04235
gene id: 1470434:AZF00_RS04235
uniprot id: A0A127M2V7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1470434:AZF00 RS07405
gene id: 1470434:AZF00_RS07405
uniprot id: A0A127M4H9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1470434:AZF00 RS02860
gene id: 1470434:AZF00_RS02860
uniprot id: A0A127MAI5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1470434:AZF00 RS05420
gene id: 1470434:AZF00_RS05420
uniprot id: A0A127M3G4
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

1470434:AZF00 RS01775
gene id: 1470434:AZF00_RS01775
uniprot id: A0A127M1M1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1470434:AZF00 RS14510
gene id: 1470434:AZF00_RS14510
uniprot id: A0A127M8A1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

1470434:AZF00 RS15025
gene id: 1470434:AZF00_RS15025
uniprot id: A0A127MB35
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1470434:AZF00 RS02725
gene id: 1470434:AZF00_RS02725
uniprot id: A0A127M209
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

1470434:AZF00 RS04005
gene id: 1470434:AZF00_RS04005
uniprot id: A0A127M2Q5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1470434:AZF00 RS01820
gene id: 1470434:AZF00_RS01820
uniprot id: A0A127M1K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

1470434:AZF00 RS07700
gene id: 1470434:AZF00_RS07700
uniprot id: A0A127M4N3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1470434:AZF00 RS05925
gene id: 1470434:AZF00_RS05925
uniprot id: A0A127M3T2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1470434:AZF00 RS10740
gene id: 1470434:AZF00_RS10740
uniprot id: A0A127M6B5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1470434:AZF00 RS11110
gene id: 1470434:AZF00_RS11110
uniprot id: A0A127M6E6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1470434:AZF00 RS11585
gene id: 1470434:AZF00_RS11585
uniprot id: A0A127M6P8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1470434:AZF00 RS00100
gene id: 1470434:AZF00_RS00100
uniprot id: A0A127M0P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

1470434:AZF00 RS03920
gene id: 1470434:AZF00_RS03920
uniprot id: A0A127M2P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS04975
gene id: 1470434:AZF00_RS04975
uniprot id: A0A127M380
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1470434:AZF00 RS08525
gene id: 1470434:AZF00_RS08525
uniprot id: A0A127M557
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS11070
gene id: 1470434:AZF00_RS11070
uniprot id: A0A127M6H7
names: Similarity
messages: Belongs to the BolA/IbaG family.

1470434:AZF00 RS06815
gene id: 1470434:AZF00_RS06815
uniprot id: A0A127M463
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1470434:AZF00 RS11645
gene id: 1470434:AZF00_RS11645
uniprot id: A0A127M6R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1470434:AZF00 RS11985
gene id: 1470434:AZF00_RS11985
uniprot id: A0A127M6T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS07625
gene id: 1470434:AZF00_RS07625
uniprot id: A0A127M4L7
names: Similarity
messages: Belongs to the UPF0276 family.

1470434:AZF00 RS07885
gene id: 1470434:AZF00_RS07885
uniprot id: A0A127M4S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1470434:AZF00 RS17980
gene id: 1470434:AZF00_RS17980
uniprot id: A0A127MA65
names: Similarity
messages: Belongs to the RutC family.

1470434:AZF00 RS01565
gene id: 1470434:AZF00_RS01565
uniprot id: A0A127M1I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1470434:AZF00 RS00270
gene id: 1470434:AZF00_RS00270
uniprot id: A0A127M0S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1470434:AZF00 RS18555
gene id: 1470434:AZF00_RS18555
uniprot id: A0A127MAA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1470434:AZF00 RS09325
gene id: 1470434:AZF00_RS09325
uniprot id: A0A127M5H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS18210
gene id: 1470434:AZF00_RS18210
uniprot id: A0A127MA43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1470434:AZF00 RS16940
gene id: 1470434:AZF00_RS16940
uniprot id: A0A127M9G1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1470434:AZF00 RS14710
gene id: 1470434:AZF00_RS14710
uniprot id: A0A127M896
names: Similarity
messages: Belongs to the BolA/IbaG family.

1470434:AZF00 RS16860
gene id: 1470434:AZF00_RS16860
uniprot id: A0A127M9L7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1470434:AZF00 RS08580
gene id: 1470434:AZF00_RS08580
uniprot id: A0A127M539
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1470434:AZF00 RS17400
gene id: 1470434:AZF00_RS17400
uniprot id: A0A127M9P2
names: Similarity
messages: Belongs to the YggT family.

1470434:AZF00 RS16920
gene id: 1470434:AZF00_RS16920
uniprot id: A0A127M9M7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1470434:AZF00 RS17780
gene id: 1470434:AZF00_RS17780
uniprot id: A0A127M9Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1470434:AZF00 RS09040
gene id: 1470434:AZF00_RS09040
uniprot id: A0A127M5J1
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

1470434:AZF00 RS15405
gene id: 1470434:AZF00_RS15405
uniprot id: A0A127M8M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1470434:AZF00 RS10560
gene id: 1470434:AZF00_RS10560
uniprot id: A0A127MAT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1470434:AZF00 RS05440
gene id: 1470434:AZF00_RS05440
uniprot id: A0A127M3F7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1470434:AZF00 RS03365
gene id: 1470434:AZF00_RS03365
uniprot id: A0A127M2D7
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1470434:AZF00 RS18425
gene id: 1470434:AZF00_RS18425
uniprot id: A0A127MA82
names: Similarity
messages: Belongs to the peptidase C56 family.

1470434:AZF00 RS12525
gene id: 1470434:AZF00_RS12525
uniprot id: A0A127M786
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS04245
gene id: 1470434:AZF00_RS04245
uniprot id: A0A127M2V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

1470434:AZF00 RS16365
gene id: 1470434:AZF00_RS16365
uniprot id: A0A127M9C6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1470434:AZF00 RS04810
gene id: 1470434:AZF00_RS04810
uniprot id: A0A127M347
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1470434:AZF00 RS01830
gene id: 1470434:AZF00_RS01830
uniprot id: A0A127M1M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1470434:AZF00 RS08350
gene id: 1470434:AZF00_RS08350
uniprot id: A0A127M4Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1470434:AZF00 RS07410
gene id: 1470434:AZF00_RS07410
uniprot id: A0A127M4J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1470434:AZF00 RS15990
gene id: 1470434:AZF00_RS15990
uniprot id: A0A127M927
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1470434:AZF00 RS00605
gene id: 1470434:AZF00_RS00605
uniprot id: A0A127M100
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS16450
gene id: 1470434:AZF00_RS16450
uniprot id: A0A127M974
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1470434:AZF00 RS11380
gene id: 1470434:AZF00_RS11380
uniprot id: A0A127MB01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1470434:AZF00 RS17170
gene id: 1470434:AZF00_RS17170
uniprot id: A0A127MAZ5
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1470434:AZF00 RS03295
gene id: 1470434:AZF00_RS03295
uniprot id: A0A127M2C9
names: Similarity
messages: Belongs to the HsdR family.

1470434:AZF00 RS15100
gene id: 1470434:AZF00_RS15100
uniprot id: A0A127M8J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1470434:AZF00 RS07560
gene id: 1470434:AZF00_RS07560
uniprot id: A0A127M4L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1470434:AZF00 RS12280
gene id: 1470434:AZF00_RS12280
uniprot id: A0A127M733
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1470434:AZF00 RS14880
gene id: 1470434:AZF00_RS14880
uniprot id: A0A127M8K5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1470434:AZF00 RS11470
gene id: 1470434:AZF00_RS11470
uniprot id: A0A127MAU8
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1470434:AZF00 RS09300
gene id: 1470434:AZF00_RS09300
uniprot id: A0A127MAQ2
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1470434:AZF00 RS09445
gene id: 1470434:AZF00_RS09445
uniprot id: A0A127M5P3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1470434:AZF00 RS08085
gene id: 1470434:AZF00_RS08085
uniprot id: A0A127M4V6
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1470434:AZF00 RS02220
gene id: 1470434:AZF00_RS02220
uniprot id: A0A127M1T0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1470434:AZF00 RS09450
gene id: 1470434:AZF00_RS09450
uniprot id: A0A127M5K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1470434:AZF00 RS14820
gene id: 1470434:AZF00_RS14820
uniprot id: A0A127M8B6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1470434:AZF00 RS09275
gene id: 1470434:AZF00_RS09275
uniprot id: A0A127M5H3
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1470434:AZF00 RS14355
gene id: 1470434:AZF00_RS14355
uniprot id: A0A127M842
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

1470434:AZF00 RS17770
gene id: 1470434:AZF00_RS17770
uniprot id: A0A127M9W0
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1470434:AZF00 RS04645
gene id: 1470434:AZF00_RS04645
uniprot id: A0A127M319
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1470434:AZF00 RS00130
gene id: 1470434:AZF00_RS00130
uniprot id: A0A127M0P6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1470434:AZF00 RS18605
gene id: 1470434:AZF00_RS18605
uniprot id: A0A127MAB1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1470434:AZF00 RS05020
gene id: 1470434:AZF00_RS05020
uniprot id: A0A127M385
names: Similarity
messages: Belongs to the LOG family.

1470434:AZF00 RS04535
gene id: 1470434:AZF00_RS04535
uniprot id: A0A127M2Z6
names: Similarity
messages: Belongs to the HIBADH-related family.

1470434:AZF00 RS00650
gene id: 1470434:AZF00_RS00650
uniprot id: A0A127M0Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1470434:AZF00 RS00815
gene id: 1470434:AZF00_RS00815
uniprot id: A0A127M141
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

1470434:AZF00 RS05210
gene id: 1470434:AZF00_RS05210
uniprot id: A0A127M3C6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

1470434:AZF00 RS11535
gene id: 1470434:AZF00_RS11535
uniprot id: A0A127M6S4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS00480
gene id: 1470434:AZF00_RS00480
uniprot id: A0A127M0X1
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1470434:AZF00 RS17685
gene id: 1470434:AZF00_RS17685
uniprot id: A0A127M9U3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1470434:AZF00 RS09645
gene id: 1470434:AZF00_RS09645
uniprot id: A0A127M5P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

1470434:AZF00 RS08120
gene id: 1470434:AZF00_RS08120
uniprot id: A0A127M4W4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1470434:AZF00 RS05205
gene id: 1470434:AZF00_RS05205
uniprot id: A0A127M3F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS05750
gene id: 1470434:AZF00_RS05750
uniprot id: A0A127M3N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS04925
gene id: 1470434:AZF00_RS04925
uniprot id: A0A127M365
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

1470434:AZF00 RS00850
gene id: 1470434:AZF00_RS00850
uniprot id: A0A127M126
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1470434:AZF00 RS09260
gene id: 1470434:AZF00_RS09260
uniprot id: A0A127M5M3
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1470434:AZF00 RS01680
gene id: 1470434:AZF00_RS01680
uniprot id: A0A127M1I5
names: Similarity
messages: Belongs to the GPAT/DAPAT family.

1470434:AZF00 RS00925
gene id: 1470434:AZF00_RS00925
uniprot id: A0A127M136
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1470434:AZF00 RS09505
gene id: 1470434:AZF00_RS09505
uniprot id: A0A127M5K9
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1470434:AZF00 RS18355
gene id: 1470434:AZF00_RS18355
uniprot id: A0A127MAD6
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1470434:AZF00 RS06910
gene id: 1470434:AZF00_RS06910
uniprot id: A0A127M480
names: Similarity
messages: Belongs to the peptidase M1 family.

1470434:AZF00 RS03340
gene id: 1470434:AZF00_RS03340
uniprot id: A0A127M2D8
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1470434:AZF00 RS03935
gene id: 1470434:AZF00_RS03935
uniprot id: A0A127M2P9
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1470434:AZF00 RS07990
gene id: 1470434:AZF00_RS07990
uniprot id: A0A127M4V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1470434:AZF00 RS16250
gene id: 1470434:AZF00_RS16250
uniprot id: A0A127M984
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1470434:AZF00 RS00685
gene id: 1470434:AZF00_RS00685
uniprot id: A0A127M0Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1470434:AZF00 RS12340
gene id: 1470434:AZF00_RS12340
uniprot id: A0A127M709
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1470434:AZF00 RS07880
gene id: 1470434:AZF00_RS07880
uniprot id: A0A127M4T7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1470434:AZF00 RS13665
gene id: 1470434:AZF00_RS13665
uniprot id: A0A127M7Z1
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

1470434:AZF00 RS15330
gene id: 1470434:AZF00_RS15330
uniprot id: A0A127M8K7
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1470434:AZF00 RS10460
gene id: 1470434:AZF00_RS10460
uniprot id: A0A127M659
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1470434:AZF00 RS14490
gene id: 1470434:AZF00_RS14490
uniprot id: A0A127M869
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

1470434:AZF00 RS13875
gene id: 1470434:AZF00_RS13875
uniprot id: A0A127M7V0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

1470434:AZF00 RS17580
gene id: 1470434:AZF00_RS17580
uniprot id: A0A127M9U5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1470434:AZF00 RS01235
gene id: 1470434:AZF00_RS01235
uniprot id: A0A127M1B6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1470434:AZF00 RS02230
gene id: 1470434:AZF00_RS02230
uniprot id: A0A127M1R8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1470434:AZF00 RS15250
gene id: 1470434:AZF00_RS15250
uniprot id: A0A127M8L9
names: Subcellular Location Annotation
messages: Cytoplasm

1470434:AZF00 RS08780
gene id: 1470434:AZF00_RS08780
uniprot id: A0A127M567
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1470434:AZF00 RS07140
gene id: 1470434:AZF00_RS07140
uniprot id: A0A127M4D4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1470434:AZF00 RS08545
gene id: 1470434:AZF00_RS08545
uniprot id: A0A127M584
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1470434:AZF00 RS10325
gene id: 1470434:AZF00_RS10325
uniprot id: A0A127M634
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

1470434:AZF00 RS07660
gene id: 1470434:AZF00_RS07660
uniprot id: A0A127M4T9
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS07040
gene id: 1470434:AZF00_RS07040
uniprot id: A0A127M4A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1470434:AZF00 RS17815
gene id: 1470434:AZF00_RS17815
uniprot id: A0A127M9W5
names: Caution
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS01700
gene id: 1470434:AZF00_RS01700
uniprot id: A0A127M1K6
names: Similarity
messages: Belongs to the peptidase S33 family.

1470434:AZF00 RS08460
gene id: 1470434:AZF00_RS08460
uniprot id: A0A127M531
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1470434:AZF00 RS03415
gene id: 1470434:AZF00_RS03415
uniprot id: A0A127M2G0
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1470434:AZF00 RS05735
gene id: 1470434:AZF00_RS05735
uniprot id: A0A127M3L1
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1470434:AZF00 RS05845
gene id: 1470434:AZF00_RS05845
uniprot id: A0A127M3W4
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1470434:AZF00 RS12515
gene id: 1470434:AZF00_RS12515
uniprot id: A0A127M740
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS16335
gene id: 1470434:AZF00_RS16335
uniprot id: A0A127M960
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1470434:AZF00 RS14480
gene id: 1470434:AZF00_RS14480
uniprot id: A0A127M8A6
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

1470434:AZF00 RS11910
gene id: 1470434:AZF00_RS11910
uniprot id: A0A127M6U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1470434:AZF00 RS08345
gene id: 1470434:AZF00_RS08345
uniprot id: A0A127M502
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1470434:AZF00 RS16225
gene id: 1470434:AZF00_RS16225
uniprot id: A0A127M947
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1470434:AZF00 RS00030
gene id: 1470434:AZF00_RS00030
uniprot id: A0A127M0M6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1470434:AZF00 RS01395
gene id: 1470434:AZF00_RS01395
uniprot id: A0A127M1C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

1470434:AZF00 RS12155
gene id: 1470434:AZF00_RS12155
uniprot id: A0A127M6Z6
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1470434:AZF00 RS03050
gene id: 1470434:AZF00_RS03050
uniprot id: A0A127M2A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1470434:AZF00 RS17620
gene id: 1470434:AZF00_RS17620
uniprot id: A0A127MA10
names: Similarity
messages: Belongs to the GSP E family.

1470434:AZF00 RS11375
gene id: 1470434:AZF00_RS11375
uniprot id: A0A127M6J0
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS09850
gene id: 1470434:AZF00_RS09850
uniprot id: A0A127M5U5
names: Similarity
messages: Belongs to the citrate synthase family.

1470434:AZF00 RS12805
gene id: 1470434:AZF00_RS12805
uniprot id: A0A127M7B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS08250
gene id: 1470434:AZF00_RS08250
uniprot id: A0A127M4Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1470434:AZF00 RS11560
gene id: 1470434:AZF00_RS11560
uniprot id: A0A127M6R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1470434:AZF00 RS02120
gene id: 1470434:AZF00_RS02120
uniprot id: A0A127M1S2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1470434:AZF00 RS00310
gene id: 1470434:AZF00_RS00310
uniprot id: A0A127M0S5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1470434:AZF00 RS07965
gene id: 1470434:AZF00_RS07965
uniprot id: A0A127M4S9
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1470434:AZF00 RS02405
gene id: 1470434:AZF00_RS02405
uniprot id: A0A127M1Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1470434:AZF00 RS00425
gene id: 1470434:AZF00_RS00425
uniprot id: A0A127M0W1
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS10500
gene id: 1470434:AZF00_RS10500
uniprot id: A0A127M661
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS17385
gene id: 1470434:AZF00_RS17385
uniprot id: A0A127M9V8
names: Similarity
messages: Belongs to the GSP E family.

1470434:AZF00 RS11440
gene id: 1470434:AZF00_RS11440
uniprot id: A0A127M6N8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1470434:AZF00 RS07490
gene id: 1470434:AZF00_RS07490
uniprot id: A0A127M4H7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1470434:AZF00 RS01340
gene id: 1470434:AZF00_RS01340
uniprot id: A0A127M1B2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1470434:AZF00 RS14390
gene id: 1470434:AZF00_RS14390
uniprot id: A0A127M8E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

1470434:AZF00 RS02855
gene id: 1470434:AZF00_RS02855
uniprot id: A0A127M258
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1470434:AZF00 RS02095
gene id: 1470434:AZF00_RS02095
uniprot id: A0A127M1P2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1470434:AZF00 RS16990
gene id: 1470434:AZF00_RS16990
uniprot id: A0A127M9H2
names: Subcellular Location Annotation
messages: Cytoplasm

1470434:AZF00 RS14275
gene id: 1470434:AZF00_RS14275
uniprot id: A0A127M8C1
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1470434:AZF00 RS11175
gene id: 1470434:AZF00_RS11175
uniprot id: A0A127M6K2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1470434:AZF00 RS13360
gene id: 1470434:AZF00_RS13360
uniprot id: A0A127M7N9
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS07920
gene id: 1470434:AZF00_RS07920
uniprot id: A0A127M4R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

1470434:AZF00 RS06035
gene id: 1470434:AZF00_RS06035
uniprot id: A0A127M3V3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1470434:AZF00 RS11060
gene id: 1470434:AZF00_RS11060
uniprot id: A0A127M6H0
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1470434:AZF00 RS06115
gene id: 1470434:AZF00_RS06115
uniprot id: A0A127M3W7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1470434:AZF00 RS06330
gene id: 1470434:AZF00_RS06330
uniprot id: A0A127M3V6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1470434:AZF00 RS01040
gene id: 1470434:AZF00_RS01040
uniprot id: A0A127M170
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1470434:AZF00 RS16625
gene id: 1470434:AZF00_RS16625
uniprot id: A0A127M996
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1470434:AZF00 RS18220
gene id: 1470434:AZF00_RS18220
uniprot id: A0A127MA67
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.
messages: Belongs to the rubredoxin family.

1470434:AZF00 RS08155
gene id: 1470434:AZF00_RS08155
uniprot id: A0A127M540
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1470434:AZF00 RS06560
gene id: 1470434:AZF00_RS06560
uniprot id: A0A127M440
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1470434:AZF00 RS07425
gene id: 1470434:AZF00_RS07425
uniprot id: A0A127M4L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1470434:AZF00 RS12395
gene id: 1470434:AZF00_RS12395
uniprot id: A0A127M716
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

1470434:AZF00 RS03490
gene id: 1470434:AZF00_RS03490
uniprot id: A0A127M2G6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1470434:AZF00 RS07530
gene id: 1470434:AZF00_RS07530
uniprot id: A0A127M4K5
names: Similarity
messages: Belongs to the bacterial secretin family.

1470434:AZF00 RS14745
gene id: 1470434:AZF00_RS14745
uniprot id: A0A127M8A8
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1470434:AZF00 RS07565
gene id: 1470434:AZF00_RS07565
uniprot id: A0A127M4M2
names: Similarity
messages: Belongs to the peptidase M16 family.

1470434:AZF00 RS00555
gene id: 1470434:AZF00_RS00555
uniprot id: A0A127M0Y9
names: Similarity
messages: Belongs to the HSP15 family.

1470434:AZF00 RS04425
gene id: 1470434:AZF00_RS04425
uniprot id: A0A127M2X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

1470434:AZF00 RS07705
gene id: 1470434:AZF00_RS07705
uniprot id: A0A127M4N7
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1470434:AZF00 RS06205
gene id: 1470434:AZF00_RS06205
uniprot id: A0A127M3W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

1470434:AZF00 RS01255
gene id: 1470434:AZF00_RS01255
uniprot id: A0A127M1B0
names: Similarity
messages: Belongs to the cytochrome P450 family.

1470434:AZF00 RS16175
gene id: 1470434:AZF00_RS16175
uniprot id: A0A127M918
names: Similarity
messages: Belongs to the cytochrome P450 family.

1470434:AZF00 RS05785
gene id: 1470434:AZF00_RS05785
uniprot id: A0A127M3M3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1470434:AZF00 RS12175
gene id: 1470434:AZF00_RS12175
uniprot id: A0A127M737
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS04585
gene id: 1470434:AZF00_RS04585
uniprot id: A0A127M304
names: Subcellular Location Annotation
messages: Cell inner membrane

1470434:AZF00 RS14475
gene id: 1470434:AZF00_RS14475
uniprot id: A0A127M870
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1470434:AZF00 RS06045
gene id: 1470434:AZF00_RS06045
uniprot id: A0A127M3S0
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

1470434:AZF00 RS10405
gene id: 1470434:AZF00_RS10405
uniprot id: A0A127M641
names: Similarity
messages: Belongs to the fatty acyl-CoA reductase family.

1470434:AZF00 RS10705
gene id: 1470434:AZF00_RS10705
uniprot id: A0A127M647
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1470434:AZF00 RS16485
gene id: 1470434:AZF00_RS16485
uniprot id: A0A127M9A5
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1470434:AZF00 RS03865
gene id: 1470434:AZF00_RS03865
uniprot id: A0A127M2N8
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

1470434:AZF00 RS08335
gene id: 1470434:AZF00_RS08335
uniprot id: A0A127MAN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1470434:AZF00 RS14230
gene id: 1470434:AZF00_RS14230
uniprot id: A0A127M859
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1470434:AZF00 RS04025
gene id: 1470434:AZF00_RS04025
uniprot id: A0A127M2S0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1470434:AZF00 RS04065
gene id: 1470434:AZF00_RS04065
uniprot id: A0A127M2R1
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1470434:AZF00 RS01520
gene id: 1470434:AZF00_RS01520
uniprot id: A0A127M1G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1470434:AZF00 RS18585
gene id: 1470434:AZF00_RS18585
uniprot id: A0A127MAB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1470434:AZF00 RS08360
gene id: 1470434:AZF00_RS08360
uniprot id: A0A127M513
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1470434:AZF00 RS18145
gene id: 1470434:AZF00_RS18145
uniprot id: A0A127MA88
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1470434:AZF00 RS17380
gene id: 1470434:AZF00_RS17380
uniprot id: A0A127M9P1
names: Similarity
messages: Belongs to the GSP E family.

1470434:AZF00 RS01600
gene id: 1470434:AZF00_RS01600
uniprot id: A0A127M1I4
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1470434:AZF00 RS14575
gene id: 1470434:AZF00_RS14575
uniprot id: A0A127M885
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1470434:AZF00 RS01180
gene id: 1470434:AZF00_RS01180
uniprot id: A0A127M194
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1470434:AZF00 RS05350
gene id: 1470434:AZF00_RS05350
uniprot id: A0A127M3G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PilY1 family.
messages: Fimbrium

1470434:AZF00 RS02215
gene id: 1470434:AZF00_RS02215
uniprot id: A0A127M1T4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1470434:AZF00 RS03410
gene id: 1470434:AZF00_RS03410
uniprot id: A0A127M2E5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1470434:AZF00 RS17735
gene id: 1470434:AZF00_RS17735
uniprot id: A0A127M9V2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1470434:AZF00 RS02395
gene id: 1470434:AZF00_RS02395
uniprot id: A0A127M1V0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1470434:AZF00 RS15000
gene id: 1470434:AZF00_RS15000
uniprot id: A0A127M8D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

1470434:AZF00 RS17340
gene id: 1470434:AZF00_RS17340
uniprot id: A0A127M9R9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1470434:AZF00 RS10815
gene id: 1470434:AZF00_RS10815
uniprot id: A0A127M6A6
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS09760
gene id: 1470434:AZF00_RS09760
uniprot id: A0A127M5Q9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1470434:AZF00 RS03475
gene id: 1470434:AZF00_RS03475
uniprot id: A0A127M2H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1470434:AZF00 RS05025
gene id: 1470434:AZF00_RS05025
uniprot id: A0A127M391
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1470434:AZF00 RS09470
gene id: 1470434:AZF00_RS09470
uniprot id: A0A127M5K2
names: Similarity
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1470434:AZF00 RS02460
gene id: 1470434:AZF00_RS02460
uniprot id: A0A127M1Z6
names: Similarity
messages: Belongs to the universal stress protein A family.

1470434:AZF00 RS18125
gene id: 1470434:AZF00_RS18125
uniprot id: A0A127MA30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS11650
gene id: 1470434:AZF00_RS11650
uniprot id: A0A127M6N0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

1470434:AZF00 RS08145
gene id: 1470434:AZF00_RS08145
uniprot id: A0A127M4U4
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1470434:AZF00 RS09955
gene id: 1470434:AZF00_RS09955
uniprot id: A0A127M5W5
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

1470434:AZF00 RS17490
gene id: 1470434:AZF00_RS17490
uniprot id: A0A127M9R3
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

1470434:AZF00 RS02285
gene id: 1470434:AZF00_RS02285
uniprot id: A0A127M1S9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1470434:AZF00 RS00095
gene id: 1470434:AZF00_RS00095
uniprot id: A0A127M0Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1470434:AZF00 RS14100
gene id: 1470434:AZF00_RS14100
uniprot id: A0A127MB31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1470434:AZF00 RS04520
gene id: 1470434:AZF00_RS04520
uniprot id: A0A127M301
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1470434:AZF00 RS04300
gene id: 1470434:AZF00_RS04300
uniprot id: A0A127M2W1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1470434:AZF00 RS02155
gene id: 1470434:AZF00_RS02155
uniprot id: A0A127M1R1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1470434:AZF00 RS14560
gene id: 1470434:AZF00_RS14560
uniprot id: A0A127M8A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

1470434:AZF00 RS08125
gene id: 1470434:AZF00_RS08125
uniprot id: A0A127M4U0
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

1470434:AZF00 RS12220
gene id: 1470434:AZF00_RS12220
uniprot id: A0A127M727
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1470434:AZF00 RS04060
gene id: 1470434:AZF00_RS04060
uniprot id: A0A127M2T8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS12120
gene id: 1470434:AZF00_RS12120
uniprot id: A0A127M704
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1470434:AZF00 RS14150
gene id: 1470434:AZF00_RS14150
uniprot id: A0A127M840
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1470434:AZF00 RS11580
gene id: 1470434:AZF00_RS11580
uniprot id: A0A127M6N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

1470434:AZF00 RS08410
gene id: 1470434:AZF00_RS08410
uniprot id: A0A127M523
names: Similarity
messages: Belongs to the YkuD family.

1470434:AZF00 RS18510
gene id: 1470434:AZF00_RS18510
uniprot id: A0A127MA96
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1470434:AZF00 RS00840
gene id: 1470434:AZF00_RS00840
uniprot id: A0A127M122
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

1470434:AZF00 RS13890
gene id: 1470434:AZF00_RS13890
uniprot id: A0A127M7X5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1470434:AZF00 RS13195
gene id: 1470434:AZF00_RS13195
uniprot id: A0A127M7K2
names: Function
messages: Binds zinc. Could be an important component of the zinc-balancing mechanism.

1470434:AZF00 RS10190
gene id: 1470434:AZF00_RS10190
uniprot id: A0A127M5U7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1470434:AZF00 RS05790
gene id: 1470434:AZF00_RS05790
uniprot id: A0A127M3M8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

1470434:AZF00 RS12535
gene id: 1470434:AZF00_RS12535
uniprot id: A0A127M795
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS18735
gene id: 1470434:AZF00_RS18735
uniprot id: A0A127MAL1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1470434:AZF00 RS08010
gene id: 1470434:AZF00_RS08010
uniprot id: A0A127M4T0
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS08695
gene id: 1470434:AZF00_RS08695
uniprot id: A0A127M587
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1470434:AZF00 RS04495
gene id: 1470434:AZF00_RS04495
uniprot id: A0A127M2Y4
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-55 and Arg-58) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1470434:AZF00 RS05940
gene id: 1470434:AZF00_RS05940
uniprot id: A0A127M3Q0
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1470434:AZF00 RS02040
gene id: 1470434:AZF00_RS02040
uniprot id: A0A127M1R4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1470434:AZF00 RS18660
gene id: 1470434:AZF00_RS18660
uniprot id: A0A127MAD2
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1470434:AZF00 RS01990
gene id: 1470434:AZF00_RS01990
uniprot id: A0A127M1N2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

1470434:AZF00 RS09980
gene id: 1470434:AZF00_RS09980
uniprot id: A0A127M5X8
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1470434:AZF00 RS15105
gene id: 1470434:AZF00_RS15105
uniprot id: A0A127M8E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1470434:AZF00 RS08225
gene id: 1470434:AZF00_RS08225
uniprot id: A0A127M4X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS14890
gene id: 1470434:AZF00_RS14890
uniprot id: A0A127M8F2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.

1470434:AZF00 RS00550
gene id: 1470434:AZF00_RS00550
uniprot id: A0A127M0W8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1470434:AZF00 RS02785
gene id: 1470434:AZF00_RS02785
uniprot id: A0A127M256
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1470434:AZF00 RS10695
gene id: 1470434:AZF00_RS10695
uniprot id: A0A127M687
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1470434:AZF00 RS07450
gene id: 1470434:AZF00_RS07450
uniprot id: A0A127M4N4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

1470434:AZF00 RS12795
gene id: 1470434:AZF00_RS12795
uniprot id: A0A127M7B0
names: Similarity
messages: Belongs to the cytochrome P450 family.

1470434:AZF00 RS07655
gene id: 1470434:AZF00_RS07655
uniprot id: A0A127M4L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1470434:AZF00 RS12090
gene id: 1470434:AZF00_RS12090
uniprot id: A0A127M713
names: Similarity
messages: Belongs to the glutamine synthetase family.

1470434:AZF00 RS10165
gene id: 1470434:AZF00_RS10165
uniprot id: A0A127M5Y8
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

1470434:AZF00 RS06995
gene id: 1470434:AZF00_RS06995
uniprot id: A0A127M492
names: Similarity
messages: Belongs to the GSP C family.

1470434:AZF00 RS10800
gene id: 1470434:AZF00_RS10800
uniprot id: A0A127M666
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS02090
gene id: 1470434:AZF00_RS02090
uniprot id: A0A127M1R6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1470434:AZF00 RS15830
gene id: 1470434:AZF00_RS15830
uniprot id: A0A127M8W1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

1470434:AZF00 RS06325
gene id: 1470434:AZF00_RS06325
uniprot id: A0A127M405
names: Similarity
messages: Belongs to the UPF0434 family.

1470434:AZF00 RS07800
gene id: 1470434:AZF00_RS07800
uniprot id: A0A127M4Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1470434:AZF00 RS09615
gene id: 1470434:AZF00_RS09615
uniprot id: A0A127M5N6
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1470434:AZF00 RS10120
gene id: 1470434:AZF00_RS10120
uniprot id: A0A127M5W0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1470434:AZF00 RS02295
gene id: 1470434:AZF00_RS02295
uniprot id: A0A127M1W6
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1470434:AZF00 RS18625
gene id: 1470434:AZF00_RS18625
uniprot id: A0A127MAJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1470434:AZF00 RS13755
gene id: 1470434:AZF00_RS13755
uniprot id: A0A127M7X3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1470434:AZF00 RS08480
gene id: 1470434:AZF00_RS08480
uniprot id: A0A127M518
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1470434:AZF00 RS01510
gene id: 1470434:AZF00_RS01510
uniprot id: A0A127M1H8
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1470434:AZF00 RS03495
gene id: 1470434:AZF00_RS03495
uniprot id: A0A127M2H1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1470434:AZF00 RS11360
gene id: 1470434:AZF00_RS11360
uniprot id: A0A127M6P6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS07865
gene id: 1470434:AZF00_RS07865
uniprot id: A0A127M4Q1
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1470434:AZF00 RS02330
gene id: 1470434:AZF00_RS02330
uniprot id: A0A127M1V2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1470434:AZF00 RS06010
gene id: 1470434:AZF00_RS06010
uniprot id: A0A127M3T8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1470434:AZF00 RS07815
gene id: 1470434:AZF00_RS07815
uniprot id: A0A127M4P1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1470434:AZF00 RS10555
gene id: 1470434:AZF00_RS10555
uniprot id: A0A127M638
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1470434:AZF00 RS16875
gene id: 1470434:AZF00_RS16875
uniprot id: A0A127M9H0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1470434:AZF00 RS01765
gene id: 1470434:AZF00_RS01765
uniprot id: A0A127M1J2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1470434:AZF00 RS04890
gene id: 1470434:AZF00_RS04890
uniprot id: A0A127M377
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1470434:AZF00 RS04185
gene id: 1470434:AZF00_RS04185
uniprot id: A0A127M2V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

1470434:AZF00 RS15110
gene id: 1470434:AZF00_RS15110
uniprot id: A0A127M8F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1470434:AZF00 RS03355
gene id: 1470434:AZF00_RS03355
uniprot id: A0A127M2D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1470434:AZF00 RS09990
gene id: 1470434:AZF00_RS09990
uniprot id: A0A127M5V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

1470434:AZF00 RS09965
gene id: 1470434:AZF00_RS09965
uniprot id: A0A127M5Q7
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1470434:AZF00 RS09530
gene id: 1470434:AZF00_RS09530
uniprot id: A0A127M5N2
names: Similarity
messages: Belongs to the fabD family.

1470434:AZF00 RS06660
gene id: 1470434:AZF00_RS06660
uniprot id: A0A127M422
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1470434:AZF00 RS12975
gene id: 1470434:AZF00_RS12975
uniprot id: A0A127M7H9
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1470434:AZF00 RS02400
gene id: 1470434:AZF00_RS02400
uniprot id: A0A127M1Z2
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1470434:AZF00 RS02205
gene id: 1470434:AZF00_RS02205
uniprot id: A0A127M1S0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1470434:AZF00 RS02225
gene id: 1470434:AZF00_RS02225
uniprot id: A0A127M1U0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1470434:AZF00 RS13230
gene id: 1470434:AZF00_RS13230
uniprot id: A0A127M7J0
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1470434:AZF00 RS05585
gene id: 1470434:AZF00_RS05585
uniprot id: A0A127M3R4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS00010
gene id: 1470434:AZF00_RS00010
uniprot id: A0A127M0M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

1470434:AZF00 RS14705
gene id: 1470434:AZF00_RS14705
uniprot id: A0A127M8C7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS00835
gene id: 1470434:AZF00_RS00835
uniprot id: A0A127M130
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1470434:AZF00 RS06270
gene id: 1470434:AZF00_RS06270
uniprot id: A0A127M3Y6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1470434:AZF00 RS14665
gene id: 1470434:AZF00_RS14665
uniprot id: A0A127M895
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1470434:AZF00 RS04800
gene id: 1470434:AZF00_RS04800
uniprot id: A0A127M350
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

1470434:AZF00 RS15425
gene id: 1470434:AZF00_RS15425
uniprot id: A0A127M8M7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1470434:AZF00 RS03870
gene id: 1470434:AZF00_RS03870
uniprot id: A0A127M2N6
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

1470434:AZF00 RS12445
gene id: 1470434:AZF00_RS12445
uniprot id: A0A127M787
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1470434:AZF00 RS07005
gene id: 1470434:AZF00_RS07005
uniprot id: A0A127M4C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

1470434:AZF00 RS11475
gene id: 1470434:AZF00_RS11475
uniprot id: A0A127M6M2
names: Function
names: Similarity
messages: Belongs to the peptidase M16 family.
messages: Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin.

1470434:AZF00 RS07525
gene id: 1470434:AZF00_RS07525
uniprot id: A0A127M4P3
names: Similarity
messages: Belongs to the GSP E family.

1470434:AZF00 RS16535
gene id: 1470434:AZF00_RS16535
uniprot id: A0A127M9B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1470434:AZF00 RS16925
gene id: 1470434:AZF00_RS16925
uniprot id: A0A127M9H1
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1470434:AZF00 RS15295
gene id: 1470434:AZF00_RS15295
uniprot id: A0A127M8P7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1470434:AZF00 RS10300
gene id: 1470434:AZF00_RS10300
uniprot id: A0A127M633
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1470434:AZF00 RS05695
gene id: 1470434:AZF00_RS05695
uniprot id: A0A127M3M7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1470434:AZF00 RS05155
gene id: 1470434:AZF00_RS05155
uniprot id: A0A127M3E5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1470434:AZF00 RS18710
gene id: 1470434:AZF00_RS18710
uniprot id: A0A127MAG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1470434:AZF00 RS06990
gene id: 1470434:AZF00_RS06990
uniprot id: A0A127M496
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1470434:AZF00 RS10290
gene id: 1470434:AZF00_RS10290
uniprot id: A0A127M627
names: Similarity
messages: Belongs to the threonine synthase family.

1470434:AZF00 RS02245
gene id: 1470434:AZF00_RS02245
uniprot id: A0A127M1V5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1470434:AZF00 RS07960
gene id: 1470434:AZF00_RS07960
uniprot id: A0A127M4U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1470434:AZF00 RS01975
gene id: 1470434:AZF00_RS01975
uniprot id: A0A127M1R7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1470434:AZF00 RS01280
gene id: 1470434:AZF00_RS01280
uniprot id: A0A127M1B4
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS06215
gene id: 1470434:AZF00_RS06215
uniprot id: A0A127M3X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS13150
gene id: 1470434:AZF00_RS13150
uniprot id: A0A127M7L1
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

1470434:AZF00 RS00410
gene id: 1470434:AZF00_RS00410
uniprot id: A0A127M0U6
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1470434:AZF00 RS07000
gene id: 1470434:AZF00_RS07000
uniprot id: A0A127M4E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

1470434:AZF00 RS04265
gene id: 1470434:AZF00_RS04265
uniprot id: A0A127M2V3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1470434:AZF00 RS14965
gene id: 1470434:AZF00_RS14965
uniprot id: A0A127MAW4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1470434:AZF00 RS01915
gene id: 1470434:AZF00_RS01915
uniprot id: A0A127M1P4
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1470434:AZF00 RS03825
gene id: 1470434:AZF00_RS03825
uniprot id: A0A127M2N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1470434:AZF00 RS04230
gene id: 1470434:AZF00_RS04230
uniprot id: A0A127M2W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1470434:AZF00 RS17150
gene id: 1470434:AZF00_RS17150
uniprot id: A0A127M9K0
names: Similarity
messages: Belongs to the thioesterase PaaI family.

1470434:AZF00 RS05910
gene id: 1470434:AZF00_RS05910
uniprot id: A0A127M3M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1470434:AZF00 RS05005
gene id: 1470434:AZF00_RS05005
uniprot id: A0A127M3C9
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1470434:AZF00 RS03015
gene id: 1470434:AZF00_RS03015
uniprot id: A0A127M270
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1470434:AZF00 RS16510
gene id: 1470434:AZF00_RS16510
uniprot id: A0A127M9E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1470434:AZF00 RS09160
gene id: 1470434:AZF00_RS09160
uniprot id: A0A127M5D6
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS07915
gene id: 1470434:AZF00_RS07915
uniprot id: A0A127M4R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1470434:AZF00 RS16325
gene id: 1470434:AZF00_RS16325
uniprot id: A0A127M970
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1470434:AZF00 RS02475
gene id: 1470434:AZF00_RS02475
uniprot id: A0A127M1W8
names: Similarity
messages: Belongs to the FrmR/RcnR family.

1470434:AZF00 RS04900
gene id: 1470434:AZF00_RS04900
uniprot id: A0A127MAK3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS14680
gene id: 1470434:AZF00_RS14680
uniprot id: A0A127MAW9
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1470434:AZF00 RS10570
gene id: 1470434:AZF00_RS10570
uniprot id: A0A127M680
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1470434:AZF00 RS05615
gene id: 1470434:AZF00_RS05615
uniprot id: A0A127M3M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1470434:AZF00 RS07925
gene id: 1470434:AZF00_RS07925
uniprot id: A0A127M4Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1470434:AZF00 RS18705
gene id: 1470434:AZF00_RS18705
uniprot id: A0A127MAF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1470434:AZF00 RS01120
gene id: 1470434:AZF00_RS01120
uniprot id: A0A127M177
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1470434:AZF00 RS14915
gene id: 1470434:AZF00_RS14915
uniprot id: A0A127M8C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1470434:AZF00 RS04540
gene id: 1470434:AZF00_RS04540
uniprot id: A0A127M2Z8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1470434:AZF00 RS01615
gene id: 1470434:AZF00_RS01615
uniprot id: A0A127M1I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1470434:AZF00 RS06530
gene id: 1470434:AZF00_RS06530
uniprot id: A0A127M419
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1470434:AZF00 RS08100
gene id: 1470434:AZF00_RS08100
uniprot id: A0A127M4V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

1470434:AZF00 RS13540
gene id: 1470434:AZF00_RS13540
uniprot id: A0A127M7Q0
names: Similarity
messages: Belongs to the bacterial secretin family.

1470434:AZF00 RS02795
gene id: 1470434:AZF00_RS02795
uniprot id: A0A127M230
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1470434:AZF00 RS16985
gene id: 1470434:AZF00_RS16985
uniprot id: A0A127M9G4
names: Similarity
messages: Belongs to the PhoH family.

1470434:AZF00 RS04935
gene id: 1470434:AZF00_RS04935
uniprot id: A0A127M382
names: Similarity
messages: Belongs to the GARS family.

1470434:AZF00 RS14940
gene id: 1470434:AZF00_RS14940
uniprot id: A0A127M8D1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS07325
gene id: 1470434:AZF00_RS07325
uniprot id: A0A127MAM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1470434:AZF00 RS06060
gene id: 1470434:AZF00_RS06060
uniprot id: A0A127M3U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS15055
gene id: 1470434:AZF00_RS15055
uniprot id: A0A127M8E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1470434:AZF00 RS03390
gene id: 1470434:AZF00_RS03390
uniprot id: A0A127M2E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1470434:AZF00 RS08990
gene id: 1470434:AZF00_RS08990
uniprot id: A0A127M5D9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1470434:AZF00 RS06735
gene id: 1470434:AZF00_RS06735
uniprot id: A0A127M452
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1470434:AZF00 RS17410
gene id: 1470434:AZF00_RS17410
uniprot id: A0A127M9R8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

1470434:AZF00 RS08290
gene id: 1470434:AZF00_RS08290
uniprot id: A0A127M4Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

1470434:AZF00 RS05120
gene id: 1470434:AZF00_RS05120
uniprot id: A0A127M3A6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS02270
gene id: 1470434:AZF00_RS02270
uniprot id: A0A127M1U3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1470434:AZF00 RS09000
gene id: 1470434:AZF00_RS09000
uniprot id: A0A127M5C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1470434:AZF00 RS03565
gene id: 1470434:AZF00_RS03565
uniprot id: A0A127M2I7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

1470434:AZF00 RS06655
gene id: 1470434:AZF00_RS06655
uniprot id: A0A127M464
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1470434:AZF00 RS04860
gene id: 1470434:AZF00_RS04860
uniprot id: A0A127M356
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS01890
gene id: 1470434:AZF00_RS01890
uniprot id: A0A127M1L3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1470434:AZF00 RS16695
gene id: 1470434:AZF00_RS16695
uniprot id: A0A127M9B0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1470434:AZF00 RS10215
gene id: 1470434:AZF00_RS10215
uniprot id: A0A127M622
names: Similarity
messages: Belongs to the transposase 7 family.

1470434:AZF00 RS01645
gene id: 1470434:AZF00_RS01645
uniprot id: A0A127M1I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS06585
gene id: 1470434:AZF00_RS06585
uniprot id: A0A127M488
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS12320
gene id: 1470434:AZF00_RS12320
uniprot id: A0A127M729
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1470434:AZF00 RS03420
gene id: 1470434:AZF00_RS03420
uniprot id: A0A127M2E8
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS14000
gene id: 1470434:AZF00_RS14000
uniprot id: A0A127M7Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

1470434:AZF00 RS04905
gene id: 1470434:AZF00_RS04905
uniprot id: A0A127M378
names: Similarity
messages: Belongs to the TrpC family.

1470434:AZF00 RS07420
gene id: 1470434:AZF00_RS07420
uniprot id: A0A127M4H4
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS14735
gene id: 1470434:AZF00_RS14735
uniprot id: A0A127M8D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

1470434:AZF00 RS07945
gene id: 1470434:AZF00_RS07945
uniprot id: A0A127M4S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1470434:AZF00 RS00670
gene id: 1470434:AZF00_RS00670
uniprot id: A0A127M101
names: Similarity
messages: Belongs to the thioredoxin family.

1470434:AZF00 RS08880
gene id: 1470434:AZF00_RS08880
uniprot id: A0A127M5A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1470434:AZF00 RS10610
gene id: 1470434:AZF00_RS10610
uniprot id: A0A127M681
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS11625
gene id: 1470434:AZF00_RS11625
uniprot id: A0A127M6S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1470434:AZF00 RS00275
gene id: 1470434:AZF00_RS00275
uniprot id: A0A127M0T7
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1470434:AZF00 RS15225
gene id: 1470434:AZF00_RS15225
uniprot id: A0A127MAZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

1470434:AZF00 RS12310
gene id: 1470434:AZF00_RS12310
uniprot id: A0A127M726
names: Subcellular Location Annotation
messages: Cell inner membrane

1470434:AZF00 RS00075
gene id: 1470434:AZF00_RS00075
uniprot id: A0A127M0N7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1470434:AZF00 RS04830
gene id: 1470434:AZF00_RS04830
uniprot id: A0A127M362
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1470434:AZF00 RS05890
gene id: 1470434:AZF00_RS05890
uniprot id: A0A127M3P8
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1470434:AZF00 RS09805
gene id: 1470434:AZF00_RS09805
uniprot id: A0A127M5Q0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1470434:AZF00 RS07025
gene id: 1470434:AZF00_RS07025
uniprot id: A0A127M4F2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

1470434:AZF00 RS15060
gene id: 1470434:AZF00_RS15060
uniprot id: A0A127M8F0
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1470434:AZF00 RS13335
gene id: 1470434:AZF00_RS13335
uniprot id: A0A127M7N0
names: Similarity
messages: Belongs to the ArsC family.

1470434:AZF00 RS00920
gene id: 1470434:AZF00_RS00920
uniprot id: A0A127M161
names: Similarity
messages: Belongs to the P(II) protein family.

1470434:AZF00 RS13450
gene id: 1470434:AZF00_RS13450
uniprot id: A0A127M7M8
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1470434:AZF00 RS14500
gene id: 1470434:AZF00_RS14500
uniprot id: A0A127M871
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1470434:AZF00 RS18640
gene id: 1470434:AZF00_RS18640
uniprot id: A0A127MAJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1470434:AZF00 RS08660
gene id: 1470434:AZF00_RS08660
uniprot id: A0A127M565
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS02260
gene id: 1470434:AZF00_RS02260
uniprot id: A0A127M1S8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1470434:AZF00 RS03280
gene id: 1470434:AZF00_RS03280
uniprot id: A0A127M2C5
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1470434:AZF00 RS16795
gene id: 1470434:AZF00_RS16795
uniprot id: A0A127M9H4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1470434:AZF00 RS16620
gene id: 1470434:AZF00_RS16620
uniprot id: A0A127M9A0
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1470434:AZF00 RS06025
gene id: 1470434:AZF00_RS06025
uniprot id: A0A127M3P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1470434:AZF00 RS15995
gene id: 1470434:AZF00_RS15995
uniprot id: A0A127M8Y9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1470434:AZF00 RS06920
gene id: 1470434:AZF00_RS06920
uniprot id: A0A127M4E1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1470434:AZF00 RS16215
gene id: 1470434:AZF00_RS16215
uniprot id: A0A127M983
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1470434:AZF00 RS05870
gene id: 1470434:AZF00_RS05870
uniprot id: A0A127M3R2
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

1470434:AZF00 RS16660
gene id: 1470434:AZF00_RS16660
uniprot id: A0A127M9D2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1470434:AZF00 RS00385
gene id: 1470434:AZF00_RS00385
uniprot id: A0A127M0V5
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS08500
gene id: 1470434:AZF00_RS08500
uniprot id: A0A127M536
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1470434:AZF00 RS18000
gene id: 1470434:AZF00_RS18000
uniprot id: A0A127MA26
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1470434:AZF00 RS01970
gene id: 1470434:AZF00_RS01970
uniprot id: A0A127M1M9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1470434:AZF00 RS04225
gene id: 1470434:AZF00_RS04225
uniprot id: A0A127M2V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1470434:AZF00 RS00390
gene id: 1470434:AZF00_RS00390
uniprot id: A0A127M0U0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

1470434:AZF00 RS16030
gene id: 1470434:AZF00_RS16030
uniprot id: A0A127M8Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1470434:AZF00 RS16690
gene id: 1470434:AZF00_RS16690
uniprot id: A0A127M9F5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1470434:AZF00 RS18310
gene id: 1470434:AZF00_RS18310
uniprot id: A0A127MAA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1470434:AZF00 RS16955
gene id: 1470434:AZF00_RS16955
uniprot id: A0A127M9N0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1470434:AZF00 RS05895
gene id: 1470434:AZF00_RS05895
uniprot id: A0A127M3X4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1470434:AZF00 RS03910
gene id: 1470434:AZF00_RS03910
uniprot id: A0A127M2N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1470434:AZF00 RS13185
gene id: 1470434:AZF00_RS13185
uniprot id: A0A127M7L9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1470434:AZF00 RS06450
gene id: 1470434:AZF00_RS06450
uniprot id: A0A127M3X9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1470434:AZF00 RS11245
gene id: 1470434:AZF00_RS11245
uniprot id: A0A127M6G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS10245
gene id: 1470434:AZF00_RS10245
uniprot id: A0A127M603
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1470434:AZF00 RS03630
gene id: 1470434:AZF00_RS03630
uniprot id: A0A127MAJ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1470434:AZF00 RS10110
gene id: 1470434:AZF00_RS10110
uniprot id: A0A127M5X7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1470434:AZF00 RS04545
gene id: 1470434:AZF00_RS04545
uniprot id: A0A127M2Z7
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1470434:AZF00 RS16100
gene id: 1470434:AZF00_RS16100
uniprot id: A0A127M963
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1470434:AZF00 RS16190
gene id: 1470434:AZF00_RS16190
uniprot id: A0A127M922
names: Function
names: Similarity
messages: Belongs to the transposase IS30 family.
messages: Required for the transposition of the insertion element.

1470434:AZF00 RS11615
gene id: 1470434:AZF00_RS11615
uniprot id: A0A127M6Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1470434:AZF00 RS18255
gene id: 1470434:AZF00_RS18255
uniprot id: A0A127MA93
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1470434:AZF00 RS12575
gene id: 1470434:AZF00_RS12575
uniprot id: A0A127M793
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1470434:AZF00 RS13260
gene id: 1470434:AZF00_RS13260
uniprot id: A0A127M7N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1470434:AZF00 RS02160
gene id: 1470434:AZF00_RS02160
uniprot id: A0A127M1S1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1470434:AZF00 RS00180
gene id: 1470434:AZF00_RS00180
uniprot id: A0A127M0Q9
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1470434:AZF00 RS10000
gene id: 1470434:AZF00_RS10000
uniprot id: A0A127M5T8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1470434:AZF00 RS16545
gene id: 1470434:AZF00_RS16545
uniprot id: A0A127M997
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1470434:AZF00 RS08665
gene id: 1470434:AZF00_RS08665
uniprot id: A0A127M542
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

1470434:AZF00 RS14515
gene id: 1470434:AZF00_RS14515
uniprot id: A0A127M893
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1470434:AZF00 RS02110
gene id: 1470434:AZF00_RS02110
uniprot id: A0A127M1R5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1470434:AZF00 RS17200
gene id: 1470434:AZF00_RS17200
uniprot id: A0A127M9M8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

1470434:AZF00 RS08625
gene id: 1470434:AZF00_RS08625
uniprot id: A0A127M5C8
names: Similarity
messages: Belongs to the transposase 7 family.

1470434:AZF00 RS02325
gene id: 1470434:AZF00_RS02325
uniprot id: A0A127MAK0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1470434:AZF00 RS12960
gene id: 1470434:AZF00_RS12960
uniprot id: A0A127M7H6
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1470434:AZF00 RS16540
gene id: 1470434:AZF00_RS16540
uniprot id: A0A127M986
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1470434:AZF00 RS05310
gene id: 1470434:AZF00_RS05310
uniprot id: A0A127M3D9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1470434:AZF00 RS02915
gene id: 1470434:AZF00_RS02915
uniprot id: A0A127M267
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1470434:AZF00 RS07790
gene id: 1470434:AZF00_RS07790
uniprot id: A0A127M4N9
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1470434:AZF00 RS05565
gene id: 1470434:AZF00_RS05565
uniprot id: A0A127M3L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

1470434:AZF00 RS11280
gene id: 1470434:AZF00_RS11280
uniprot id: A0A127M6L7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1470434:AZF00 RS00380
gene id: 1470434:AZF00_RS00380
uniprot id: A0A127M0U8
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS00015
gene id: 1470434:AZF00_RS00015
uniprot id: A0A127M0N1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS16355
gene id: 1470434:AZF00_RS16355
uniprot id: A0A127M998
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1470434:AZF00 RS13800
gene id: 1470434:AZF00_RS13800
uniprot id: A0A127M7U1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1470434:AZF00 RS08420
gene id: 1470434:AZF00_RS08420
uniprot id: A0A127M537
names: Similarity
messages: Belongs to the MlaA family.

1470434:AZF00 RS08245
gene id: 1470434:AZF00_RS08245
uniprot id: A0A127M4V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1470434:AZF00 RS01895
gene id: 1470434:AZF00_RS01895
uniprot id: A0A127M1M4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1470434:AZF00 RS14545
gene id: 1470434:AZF00_RS14545
uniprot id: A0A127M8G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1470434:AZF00 RS06890
gene id: 1470434:AZF00_RS06890
uniprot id: A0A127M476
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS18740
gene id: 1470434:AZF00_RS18740
uniprot id: A0A127MAH9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1470434:AZF00 RS07015
gene id: 1470434:AZF00_RS07015
uniprot id: A0A127M499
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

1470434:AZF00 RS08875
gene id: 1470434:AZF00_RS08875
uniprot id: A0A127M588
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1470434:AZF00 RS02175
gene id: 1470434:AZF00_RS02175
uniprot id: A0A127M1T1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1470434:AZF00 RS19460
gene id: 1470434:AZF00_RS19460
uniprot id: A0A127M444
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1470434:AZF00 RS06445
gene id: 1470434:AZF00_RS06445
uniprot id: A0A127M3Y2
names: Similarity
messages: Belongs to the peptidase S33 family.

1470434:AZF00 RS03560
gene id: 1470434:AZF00_RS03560
uniprot id: A0A127M2H4
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

1470434:AZF00 RS13035
gene id: 1470434:AZF00_RS13035
uniprot id: A0A127M7H4
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1470434:AZF00 RS06535
gene id: 1470434:AZF00_RS06535
uniprot id: A0A127M479
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1470434:AZF00 RS01910
gene id: 1470434:AZF00_RS01910
uniprot id: A0A127M1N0
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1470434:AZF00 RS09180
gene id: 1470434:AZF00_RS09180
uniprot id: A0A127M5F4
names: Similarity
messages: Belongs to the peptidase S49 family.

1470434:AZF00 RS09170
gene id: 1470434:AZF00_RS09170
uniprot id: A0A127M5D8
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS14570
gene id: 1470434:AZF00_RS14570
uniprot id: A0A127M864
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1470434:AZF00 RS10660
gene id: 1470434:AZF00_RS10660
uniprot id: A0A127M6A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1470434:AZF00 RS16675
gene id: 1470434:AZF00_RS16675
uniprot id: A0A127M9A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1470434:AZF00 RS06470
gene id: 1470434:AZF00_RS06470
uniprot id: A0A127M401
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

1470434:AZF00 RS04970
gene id: 1470434:AZF00_RS04970
uniprot id: A0A127M379
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1470434:AZF00 RS05660
gene id: 1470434:AZF00_RS05660
uniprot id: A0A127M3L8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS17325
gene id: 1470434:AZF00_RS17325
uniprot id: A0A127M9M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1470434:AZF00 RS17360
gene id: 1470434:AZF00_RS17360
uniprot id: A0A127M9Q7
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1470434:AZF00 RS13710
gene id: 1470434:AZF00_RS13710
uniprot id: A0A127M7U2
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1470434:AZF00 RS13475
gene id: 1470434:AZF00_RS13475
uniprot id: A0A127M7S8
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS07795
gene id: 1470434:AZF00_RS07795
uniprot id: A0A127M4U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1470434:AZF00 RS16360
gene id: 1470434:AZF00_RS16360
uniprot id: A0A127M959
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1470434:AZF00 RS10115
gene id: 1470434:AZF00_RS10115
uniprot id: A0A127M5Z4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1470434:AZF00 RS03635
gene id: 1470434:AZF00_RS03635
uniprot id: A0A127M2J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1470434:AZF00 RS05520
gene id: 1470434:AZF00_RS05520
uniprot id: A0A127MAU2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1470434:AZF00 RS08870
gene id: 1470434:AZF00_RS08870
uniprot id: A0A127M5B9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1470434:AZF00 RS15945
gene id: 1470434:AZF00_RS15945
uniprot id: A0A127M935
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1470434:AZF00 RS18675
gene id: 1470434:AZF00_RS18675
uniprot id: A0A127MAD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1470434:AZF00 RS00080
gene id: 1470434:AZF00_RS00080
uniprot id: A0A127M0N4
names: Similarity
messages: Belongs to the DinB family.

1470434:AZF00 RS09155
gene id: 1470434:AZF00_RS09155
uniprot id: A0A127M5G8
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS09440
gene id: 1470434:AZF00_RS09440
uniprot id: A0A127M5K6
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1470434:AZF00 RS13995
gene id: 1470434:AZF00_RS13995
uniprot id: A0A127M7Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1470434:AZF00 RS03500
gene id: 1470434:AZF00_RS03500
uniprot id: A0A127M2I2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1470434:AZF00 RS06595
gene id: 1470434:AZF00_RS06595
uniprot id: A0A127M458
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS09580
gene id: 1470434:AZF00_RS09580
uniprot id: A0A127M5S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1470434:AZF00 RS09740
gene id: 1470434:AZF00_RS09740
uniprot id: A0A127M5T6
names: Subcellular Location Annotation
messages: Cytoplasm

1470434:AZF00 RS00140
gene id: 1470434:AZF00_RS00140
uniprot id: A0A127M0P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1470434:AZF00 RS14050
gene id: 1470434:AZF00_RS14050
uniprot id: A0A127M7Z5
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

1470434:AZF00 RS02350
gene id: 1470434:AZF00_RS02350
uniprot id: A0A127M1X9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1470434:AZF00 RS04305
gene id: 1470434:AZF00_RS04305
uniprot id: A0A127M2V9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS18420
gene id: 1470434:AZF00_RS18420
uniprot id: A0A127MAB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS06235
gene id: 1470434:AZF00_RS06235
uniprot id: A0A127M3X8
names: Similarity
messages: Belongs to the cytochrome P450 family.

1470434:AZF00 RS05380
gene id: 1470434:AZF00_RS05380
uniprot id: A0A127M3I5
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1470434:AZF00 RS14255
gene id: 1470434:AZF00_RS14255
uniprot id: A0A127M857
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1470434:AZF00 RS09465
gene id: 1470434:AZF00_RS09465
uniprot id: A0A127M5I0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1470434:AZF00 RS14210
gene id: 1470434:AZF00_RS14210
uniprot id: A0A127M823
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PilY1 family.
messages: Fimbrium

1470434:AZF00 RS07150
gene id: 1470434:AZF00_RS07150
uniprot id: A0A127M4C5
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1470434:AZF00 RS14240
gene id: 1470434:AZF00_RS14240
uniprot id: A0A127MAX1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1470434:AZF00 RS08200
gene id: 1470434:AZF00_RS08200
uniprot id: A0A127M4X5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1470434:AZF00 RS02280
gene id: 1470434:AZF00_RS02280
uniprot id: A0A127M1V1
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1470434:AZF00 RS04040
gene id: 1470434:AZF00_RS04040
uniprot id: A0A127M2R7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1470434:AZF00 RS09200
gene id: 1470434:AZF00_RS09200
uniprot id: A0A127M5L8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1470434:AZF00 RS07940
gene id: 1470434:AZF00_RS07940
uniprot id: A0A127M4S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1470434:AZF00 RS03795
gene id: 1470434:AZF00_RS03795
uniprot id: A0A127M2L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS02845
gene id: 1470434:AZF00_RS02845
uniprot id: A0A127M243
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1470434:AZF00 RS17320
gene id: 1470434:AZF00_RS17320
uniprot id: A0A127M9N3
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

1470434:AZF00 RS16330
gene id: 1470434:AZF00_RS16330
uniprot id: A0A127M950
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1470434:AZF00 RS12360
gene id: 1470434:AZF00_RS12360
uniprot id: A0A127M739
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1470434:AZF00 RS04805
gene id: 1470434:AZF00_RS04805
uniprot id: A0A127M349
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

1470434:AZF00 RS01295
gene id: 1470434:AZF00_RS01295
uniprot id: A0A127M1D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1470434:AZF00 RS09995
gene id: 1470434:AZF00_RS09995
uniprot id: A0A127M5X2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribosome modulation factor family.
messages: Cytoplasm
messages: During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).

1470434:AZF00 RS12500
gene id: 1470434:AZF00_RS12500
uniprot id: A0A127M798
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1470434:AZF00 RS00305
gene id: 1470434:AZF00_RS00305
uniprot id: A0A127M0S7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1470434:AZF00 RS08550
gene id: 1470434:AZF00_RS08550
uniprot id: A0A127M543
names: Similarity
messages: Belongs to the GST superfamily.

1470434:AZF00 RS07475
gene id: 1470434:AZF00_RS07475
uniprot id: A0A127M4N2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1470434:AZF00 RS14795
gene id: 1470434:AZF00_RS14795
uniprot id: A0A127M899
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1470434:AZF00 RS07030
gene id: 1470434:AZF00_RS07030
uniprot id: A0A127M4C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

1470434:AZF00 RS16520
gene id: 1470434:AZF00_RS16520
uniprot id: A0A127M985
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1470434:AZF00 RS01525
gene id: 1470434:AZF00_RS01525
uniprot id: A0A127M1E0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1470434:AZF00 RS11025
gene id: 1470434:AZF00_RS11025
uniprot id: A0A127M6C6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1470434:AZF00 RS14375
gene id: 1470434:AZF00_RS14375
uniprot id: A0A127M889
names: Similarity
messages: Belongs to the UPF0234 family.

1470434:AZF00 RS08315
gene id: 1470434:AZF00_RS08315
uniprot id: A0A127M517
names: Subcellular Location Annotation
messages: Cytoplasm

1470434:AZF00 RS13205
gene id: 1470434:AZF00_RS13205
uniprot id: A0A127M7I9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1470434:AZF00 RS16585
gene id: 1470434:AZF00_RS16585
uniprot id: A0A127M994
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1470434:AZF00 RS11855
gene id: 1470434:AZF00_RS11855
uniprot id: A0A127M6W0
names: Similarity
messages: Belongs to the thioesterase PaaI family.

1470434:AZF00 RS09930
gene id: 1470434:AZF00_RS09930
uniprot id: A0A127M5X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1470434:AZF00 RS07045
gene id: 1470434:AZF00_RS07045
uniprot id: A0A127M4A0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1470434:AZF00 RS15185
gene id: 1470434:AZF00_RS15185
uniprot id: A0A127M8Q2
names: Similarity
messages: Belongs to the SfsA family.

1470434:AZF00 RS18635
gene id: 1470434:AZF00_RS18635
uniprot id: A0A127MAC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1470434:AZF00 RS14495
gene id: 1470434:AZF00_RS14495
uniprot id: A0A127M8G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

1470434:AZF00 RS09435
gene id: 1470434:AZF00_RS09435
uniprot id: A0A127M5L1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1470434:AZF00 RS07370
gene id: 1470434:AZF00_RS07370
uniprot id: A0A127M4L0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1470434:AZF00 RS00660
gene id: 1470434:AZF00_RS00660
uniprot id: A0A127M110
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

1470434:AZF00 RS06525
gene id: 1470434:AZF00_RS06525
uniprot id: A0A127M410
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS11885
gene id: 1470434:AZF00_RS11885
uniprot id: A0A127M6R3
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1470434:AZF00 RS17630
gene id: 1470434:AZF00_RS17630
uniprot id: A0A127M9V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1470434:AZF00 RS09455
gene id: 1470434:AZF00_RS09455
uniprot id: A0A127M5I3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1470434:AZF00 RS18780
gene id: 1470434:AZF00_RS18780
uniprot id: A0A127MAF2
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1470434:AZF00 RS15810
gene id: 1470434:AZF00_RS15810
uniprot id: A0A127M8T4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1470434:AZF00 RS09195
gene id: 1470434:AZF00_RS09195
uniprot id: A0A127M5G0
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1470434:AZF00 RS14155
gene id: 1470434:AZF00_RS14155
uniprot id: A0A127M820
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1470434:AZF00 RS01840
gene id: 1470434:AZF00_RS01840
uniprot id: A0A127M1K1
names: Cofactor
messages: Can also use Mn(2+) ion.

1470434:AZF00 RS13565
gene id: 1470434:AZF00_RS13565
uniprot id: A0A127M7Q1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1470434:AZF00 RS10640
gene id: 1470434:AZF00_RS10640
uniprot id: A0A127M671
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1470434:AZF00 RS06400
gene id: 1470434:AZF00_RS06400
uniprot id: A0A127M3X0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1470434:AZF00 RS18695
gene id: 1470434:AZF00_RS18695
uniprot id: A0A127MAK9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS14605
gene id: 1470434:AZF00_RS14605
uniprot id: A0A127MB25
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1470434:AZF00 RS15080
gene id: 1470434:AZF00_RS15080
uniprot id: A0A127M8N1
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS09075
gene id: 1470434:AZF00_RS09075
uniprot id: A0A127M5B4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1470434:AZF00 RS01535
gene id: 1470434:AZF00_RS01535
uniprot id: A0A127M1F7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1470434:AZF00 RS10395
gene id: 1470434:AZF00_RS10395
uniprot id: A0A127M602
names: Similarity
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.

1470434:AZF00 RS15635
gene id: 1470434:AZF00_RS15635
uniprot id: A0A127M8T8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1470434:AZF00 RS18630
gene id: 1470434:AZF00_RS18630
uniprot id: A0A127MAF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1470434:AZF00 RS14360
gene id: 1470434:AZF00_RS14360
uniprot id: A0A127M830
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1470434:AZF00 RS10915
gene id: 1470434:AZF00_RS10915
uniprot id: A0A127M6D1
names: Similarity
messages: Belongs to the UPF0047 family.

1470434:AZF00 RS10550
gene id: 1470434:AZF00_RS10550
uniprot id: A0A127M672
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS02505
gene id: 1470434:AZF00_RS02505
uniprot id: A0A127M211
names: Similarity
messages: Belongs to the cytochrome P450 family.

1470434:AZF00 RS06620
gene id: 1470434:AZF00_RS06620
uniprot id: A0A127M460
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1470434:AZF00 RS12390
gene id: 1470434:AZF00_RS12390
uniprot id: A0A127M715
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

1470434:AZF00 RS05300
gene id: 1470434:AZF00_RS05300
uniprot id: A0A127M3F4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1470434:AZF00 RS10095
gene id: 1470434:AZF00_RS10095
uniprot id: A0A127M5X5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS15825
gene id: 1470434:AZF00_RS15825
uniprot id: A0A127M8Z7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1470434:AZF00 RS10795
gene id: 1470434:AZF00_RS10795
uniprot id: A0A127M6A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

1470434:AZF00 RS16570
gene id: 1470434:AZF00_RS16570
uniprot id: A0A127M9D6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1470434:AZF00 RS11635
gene id: 1470434:AZF00_RS11635
uniprot id: A0A127M6Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1470434:AZF00 RS04655
gene id: 1470434:AZF00_RS04655
uniprot id: A0A127M316
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1470434:AZF00 RS17615
gene id: 1470434:AZF00_RS17615
uniprot id: A0A127M9T2
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1470434:AZF00 RS04475
gene id: 1470434:AZF00_RS04475
uniprot id: A0A127M305
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1470434:AZF00 RS00755
gene id: 1470434:AZF00_RS00755
uniprot id: A0A127MAN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

1470434:AZF00 RS09360
gene id: 1470434:AZF00_RS09360
uniprot id: A0A127M5I6
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1470434:AZF00 RS01070
gene id: 1470434:AZF00_RS01070
uniprot id: A0A127M166
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1470434:AZF00 RS01130
gene id: 1470434:AZF00_RS01130
uniprot id: A0A127M184
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1470434:AZF00 RS06665
gene id: 1470434:AZF00_RS06665
uniprot id: A0A127M417
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1470434:AZF00 RS04400
gene id: 1470434:AZF00_RS04400
uniprot id: A0A127M2Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

1470434:AZF00 RS19440
gene id: 1470434:AZF00_RS19440
uniprot id: A0A127M3A9
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1470434:AZF00 RS10040
gene id: 1470434:AZF00_RS10040
uniprot id: A0A127M5Z9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1470434:AZF00 RS11065
gene id: 1470434:AZF00_RS11065
uniprot id: A0A127M6G3
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1470434:AZF00 RS06125
gene id: 1470434:AZF00_RS06125
uniprot id: A0A127M3R6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1470434:AZF00 RS12370
gene id: 1470434:AZF00_RS12370
uniprot id: A0A127M734
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1470434:AZF00 RS13025
gene id: 1470434:AZF00_RS13025
uniprot id: A0A127M7I7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1470434:AZF00 RS06040
gene id: 1470434:AZF00_RS06040
uniprot id: A0A127M3R9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1470434:AZF00 RS14135
gene id: 1470434:AZF00_RS14135
uniprot id: A0A127M7Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1470434:AZF00 RS15265
gene id: 1470434:AZF00_RS15265
uniprot id: A0A127M8K2
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

1470434:AZF00 RS14550
gene id: 1470434:AZF00_RS14550
uniprot id: A0A127M878
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1470434:AZF00 RS11575
gene id: 1470434:AZF00_RS11575
uniprot id: A0A127M6S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1470434:AZF00 RS01685
gene id: 1470434:AZF00_RS01685
uniprot id: A0A127M1I8
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1470434:AZF00 RS18335
gene id: 1470434:AZF00_RS18335
uniprot id: A0A127MA63
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS13740
gene id: 1470434:AZF00_RS13740
uniprot id: A0A127M7S4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1470434:AZF00 RS03615
gene id: 1470434:AZF00_RS03615
uniprot id: A0A127M2I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1470434:AZF00 RS18725
gene id: 1470434:AZF00_RS18725
uniprot id: A0A127MAD5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1470434:AZF00 RS19560
gene id: 1470434:AZF00_RS19560
uniprot id: A0A127M248
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1470434:AZF00 RS01320
gene id: 1470434:AZF00_RS01320
uniprot id: A0A127M1B8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1470434:AZF00 RS06555
gene id: 1470434:AZF00_RS06555
uniprot id: A0A127M400
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1470434:AZF00 RS00970
gene id: 1470434:AZF00_RS00970
uniprot id: A0A127M171
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1470434:AZF00 RS04500
gene id: 1470434:AZF00_RS04500
uniprot id: A0A127M2Z1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1470434:AZF00 RS12505
gene id: 1470434:AZF00_RS12505
uniprot id: A0A127M765
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1470434:AZF00 RS08105
gene id: 1470434:AZF00_RS08105
uniprot id: A0A127M530
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1470434:AZF00 RS10305
gene id: 1470434:AZF00_RS10305
uniprot id: A0A127M615
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1470434:AZF00 RS01885
gene id: 1470434:AZF00_RS01885
uniprot id: A0A127M1N1
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS07430
gene id: 1470434:AZF00_RS07430
uniprot id: A0A127M4I5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1470434:AZF00 RS14290
gene id: 1470434:AZF00_RS14290
uniprot id: A0A127M862
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

1470434:AZF00 RS06185
gene id: 1470434:AZF00_RS06185
uniprot id: A0A127MAL4
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

1470434:AZF00 RS18795
gene id: 1470434:AZF00_RS18795
uniprot id: A0A127MAF4
names: Similarity
messages: Belongs to the DprA/Smf family.

1470434:AZF00 RS13815
gene id: 1470434:AZF00_RS13815
uniprot id: A0A127M7W4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS00485
gene id: 1470434:AZF00_RS00485
uniprot id: A0A127M0W4
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1470434:AZF00 RS13605
gene id: 1470434:AZF00_RS13605
uniprot id: A0A127M7R8
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS14725
gene id: 1470434:AZF00_RS14725
uniprot id: A0A127M8D4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

1470434:AZF00 RS03395
gene id: 1470434:AZF00_RS03395
uniprot id: A0A127M2E6
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1470434:AZF00 RS03020
gene id: 1470434:AZF00_RS03020
uniprot id: A0A127M287
names: Function
names: Similarity
messages: Belongs to the vsr family.
messages: May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.

1470434:AZF00 RS15595
gene id: 1470434:AZF00_RS15595
uniprot id: A0A127M8S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS00845
gene id: 1470434:AZF00_RS00845
uniprot id: A0A127M124
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1470434:AZF00 RS05145
gene id: 1470434:AZF00_RS05145
uniprot id: A0A127M3A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1470434:AZF00 RS01610
gene id: 1470434:AZF00_RS01610
uniprot id: A0A127M1J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1470434:AZF00 RS15925
gene id: 1470434:AZF00_RS15925
uniprot id: A0A127M8X3
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS09815
gene id: 1470434:AZF00_RS09815
uniprot id: A0A127M5V3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1470434:AZF00 RS18315
gene id: 1470434:AZF00_RS18315
uniprot id: A0A127MA62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS04115
gene id: 1470434:AZF00_RS04115
uniprot id: A0A127M2U8
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1470434:AZF00 RS11480
gene id: 1470434:AZF00_RS11480
uniprot id: A0A127M6R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1470434:AZF00 RS02300
gene id: 1470434:AZF00_RS02300
uniprot id: A0A127M1V4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1470434:AZF00 RS08070
gene id: 1470434:AZF00_RS08070
uniprot id: A0A127M4T5
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS13020
gene id: 1470434:AZF00_RS13020
uniprot id: A0A127M7E9
names: Similarity
messages: Belongs to the pyruvate kinase family.

1470434:AZF00 RS01000
gene id: 1470434:AZF00_RS01000
uniprot id: A0A127M153
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

1470434:AZF00 RS11975
gene id: 1470434:AZF00_RS11975
uniprot id: A0A127M6X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

1470434:AZF00 RS04720
gene id: 1470434:AZF00_RS04720
uniprot id: A0A127M345
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1470434:AZF00 RS04050
gene id: 1470434:AZF00_RS04050
uniprot id: A0A127M2Q9
names: Similarity
messages: Belongs to the GPAT/DAPAT family.

1470434:AZF00 RS13685
gene id: 1470434:AZF00_RS13685
uniprot id: A0A127M7V9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

1470434:AZF00 RS05000
gene id: 1470434:AZF00_RS05000
uniprot id: A0A127M394
names: Similarity
messages: Belongs to the thioredoxin family.

1470434:AZF00 RS01305
gene id: 1470434:AZF00_RS01305
uniprot id: A0A127M1C1
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1470434:AZF00 RS04205
gene id: 1470434:AZF00_RS04205
uniprot id: A0A127M2T5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1470434:AZF00 RS03575
gene id: 1470434:AZF00_RS03575
uniprot id: A0A127M2I6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

1470434:AZF00 RS14260
gene id: 1470434:AZF00_RS14260
uniprot id: A0A127MAX7
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1470434:AZF00 RS13055
gene id: 1470434:AZF00_RS13055
uniprot id: A0A127M7F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1470434:AZF00 RS01215
gene id: 1470434:AZF00_RS01215
uniprot id: A0A127M195
names: Similarity
messages: Belongs to the HepT RNase toxin family.

1470434:AZF00 RS06895
gene id: 1470434:AZF00_RS06895
uniprot id: A0A127M4B3
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS12450
gene id: 1470434:AZF00_RS12450
uniprot id: A0A127M752
names: Similarity
messages: Belongs to the Skp family.

1470434:AZF00 RS18035
gene id: 1470434:AZF00_RS18035
uniprot id: A0A127MA52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1470434:AZF00 RS10615
gene id: 1470434:AZF00_RS10615
uniprot id: A0A127M652
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

1470434:AZF00 RS11640
gene id: 1470434:AZF00_RS11640
uniprot id: A0A127M6U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1470434:AZF00 RS11295
gene id: 1470434:AZF00_RS11295
uniprot id: A0A127M6I7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1470434:AZF00 RS04240
gene id: 1470434:AZF00_RS04240
uniprot id: A0A127M2W4
names: Function
names: Similarity
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.

1470434:AZF00 RS07440
gene id: 1470434:AZF00_RS07440
uniprot id: A0A127M4G8
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1470434:AZF00 RS15085
gene id: 1470434:AZF00_RS15085
uniprot id: A0A127M8H5
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

1470434:AZF00 RS02345
gene id: 1470434:AZF00_RS02345
uniprot id: A0A127M1T9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS14825
gene id: 1470434:AZF00_RS14825
uniprot id: A0A127M8J9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1470434:AZF00 RS10285
gene id: 1470434:AZF00_RS10285
uniprot id: A0A127M610
names: Similarity
messages: Belongs to the RecJ family.

1470434:AZF00 RS16810
gene id: 1470434:AZF00_RS16810
uniprot id: A0A127M9F3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1470434:AZF00 RS17500
gene id: 1470434:AZF00_RS17500
uniprot id: A0A127M9R1
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1470434:AZF00 RS15245
gene id: 1470434:AZF00_RS15245
uniprot id: A0A127M8Q6
names: Similarity
messages: Belongs to the DEAD box helicase family.

1470434:AZF00 RS03885
gene id: 1470434:AZF00_RS03885
uniprot id: A0A127M2N3
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1470434:AZF00 RS07590
gene id: 1470434:AZF00_RS07590
uniprot id: A0A127M4L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1470434:AZF00 RS14235
gene id: 1470434:AZF00_RS14235
uniprot id: A0A127M813
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1470434:AZF00 RS00955
gene id: 1470434:AZF00_RS00955
uniprot id: A0A127M146
names: Similarity
messages: Belongs to the P(II) protein family.

1470434:AZF00 RS03760
gene id: 1470434:AZF00_RS03760
uniprot id: A0A127M2L9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1470434:AZF00 RS09985
gene id: 1470434:AZF00_RS09985
uniprot id: A0A127M5Y9
names: Subcellular Location Annotation
messages: Cytoplasm

1470434:AZF00 RS18300
gene id: 1470434:AZF00_RS18300
uniprot id: A0A127MA64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1470434:AZF00 RS08030
gene id: 1470434:AZF00_RS08030
uniprot id: A0A127M4Y5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1470434:AZF00 RS16530
gene id: 1470434:AZF00_RS16530
uniprot id: A0A127M9A8
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1470434:AZF00 RS12885
gene id: 1470434:AZF00_RS12885
uniprot id: A0A127M7B9
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1470434:AZF00 RS14295
gene id: 1470434:AZF00_RS14295
uniprot id: A0A127M866
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1470434:AZF00 RS17775
gene id: 1470434:AZF00_RS17775
uniprot id: A0A127MA25
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1470434:AZF00 RS15065
gene id: 1470434:AZF00_RS15065
uniprot id: A0A127M8L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1470434:AZF00 RS04850
gene id: 1470434:AZF00_RS04850
uniprot id: A0A127M357
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1470434:AZF00 RS13810
gene id: 1470434:AZF00_RS13810
uniprot id: A0A127M7Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1470434:AZF00 RS01185
gene id: 1470434:AZF00_RS01185
uniprot id: A0A127M1A7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1470434:AZF00 RS06515
gene id: 1470434:AZF00_RS06515
uniprot id: A0A127M442
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS00625
gene id: 1470434:AZF00_RS00625
uniprot id: A0A127M0Y4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS08175
gene id: 1470434:AZF00_RS08175
uniprot id: A0A127M4V9
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1470434:AZF00 RS14055
gene id: 1470434:AZF00_RS14055
uniprot id: A0A127M865
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1470434:AZF00 RS01135
gene id: 1470434:AZF00_RS01135
uniprot id: A0A127M1A2
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS04505
gene id: 1470434:AZF00_RS04505
uniprot id: A0A127M2Y0
names: Similarity
messages: Belongs to the PhzF family.

1470434:AZF00 RS09355
gene id: 1470434:AZF00_RS09355
uniprot id: A0A127M5F7
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1470434:AZF00 RS13735
gene id: 1470434:AZF00_RS13735
uniprot id: A0A127M7W9
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1470434:AZF00 RS07515
gene id: 1470434:AZF00_RS07515
uniprot id: A0A127M4J9
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS12385
gene id: 1470434:AZF00_RS12385
uniprot id: A0A127M747
names: Similarity
messages: Belongs to the HesB/IscA family.

1470434:AZF00 RS02930
gene id: 1470434:AZF00_RS02930
uniprot id: A0A127M273
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

1470434:AZF00 RS02610
gene id: 1470434:AZF00_RS02610
uniprot id: A0A127M210
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1470434:AZF00 RS06120
gene id: 1470434:AZF00_RS06120
uniprot id: A0A127M3R7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1470434:AZF00 RS10530
gene id: 1470434:AZF00_RS10530
uniprot id: A0A127M649
names: Similarity
messages: Belongs to the TrpF family.

1470434:AZF00 RS04375
gene id: 1470434:AZF00_RS04375
uniprot id: A0A127M2W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1470434:AZF00 RS10125
gene id: 1470434:AZF00_RS10125
uniprot id: A0A127M5Z5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1470434:AZF00 RS18785
gene id: 1470434:AZF00_RS18785
uniprot id: A0A127MAM2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1470434:AZF00 RS15435
gene id: 1470434:AZF00_RS15435
uniprot id: A0A127M8M1
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1470434:AZF00 RS13110
gene id: 1470434:AZF00_RS13110
uniprot id: A0A127M7G8
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS11900
gene id: 1470434:AZF00_RS11900
uniprot id: A0A127M6U6
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1470434:AZF00 RS09365
gene id: 1470434:AZF00_RS09365
uniprot id: A0A127M5P2
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1470434:AZF00 RS00090
gene id: 1470434:AZF00_RS00090
uniprot id: A0A127M0N5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1470434:AZF00 RS08485
gene id: 1470434:AZF00_RS08485
uniprot id: A0A127M535
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1470434:AZF00 RS08935
gene id: 1470434:AZF00_RS08935
uniprot id: A0A127M5B1
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1470434:AZF00 RS05230
gene id: 1470434:AZF00_RS05230
uniprot id: A0A127M3D6
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1470434:AZF00 RS04140
gene id: 1470434:AZF00_RS04140
uniprot id: A0A127M2T2
names: Similarity
messages: Belongs to the peptidase S45 family.

1470434:AZF00 RS15215
gene id: 1470434:AZF00_RS15215
uniprot id: A0A127M8G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1470434:AZF00 RS12035
gene id: 1470434:AZF00_RS12035
uniprot id: A0A127M6U8
names: Function
names: Similarity
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: In the C-terminal section; belongs to the radical SAM superfamily. CofH family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. CofG family.

1470434:AZF00 RS12330
gene id: 1470434:AZF00_RS12330
uniprot id: A0A127M767
names: Similarity
messages: Belongs to the YfgM family.

1470434:AZF00 RS10525
gene id: 1470434:AZF00_RS10525
uniprot id: A0A127M620
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1470434:AZF00 RS07350
gene id: 1470434:AZF00_RS07350
uniprot id: A0A127M4H2
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS04610
gene id: 1470434:AZF00_RS04610
uniprot id: A0A127M303
names: Similarity
messages: Belongs to the cytochrome P450 family.

1470434:AZF00 RS05730
gene id: 1470434:AZF00_RS05730
uniprot id: A0A127M3K8
names: Similarity
messages: Belongs to the cytochrome P450 family.

1470434:AZF00 RS07185
gene id: 1470434:AZF00_RS07185
uniprot id: A0A127M4I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1470434:AZF00 RS04795
gene id: 1470434:AZF00_RS04795
uniprot id: A0A127M346
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

1470434:AZF00 RS11170
gene id: 1470434:AZF00_RS11170
uniprot id: A0A127M6F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1470434:AZF00 RS16890
gene id: 1470434:AZF00_RS16890
uniprot id: A0A127M9F4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1470434:AZF00 RS11370
gene id: 1470434:AZF00_RS11370
uniprot id: A0A127M6J6
names: Similarity
messages: Belongs to the SCO1/2 family.

1470434:AZF00 RS03385
gene id: 1470434:AZF00_RS03385
uniprot id: A0A127M2F3
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1470434:AZF00 RS17995
gene id: 1470434:AZF00_RS17995
uniprot id: A0A127MA79
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1470434:AZF00 RS13075
gene id: 1470434:AZF00_RS13075
uniprot id: A0A127M7J6
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1470434:AZF00 RS09725
gene id: 1470434:AZF00_RS09725
uniprot id: A0A127M5T1
names: Similarity
messages: Belongs to the UPF0270 family.

1470434:AZF00 RS13975
gene id: 1470434:AZF00_RS13975
uniprot id: A0A127M7V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1470434:AZF00 RS12140
gene id: 1470434:AZF00_RS12140
uniprot id: A0A127M6W9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1470434:AZF00 RS16915
gene id: 1470434:AZF00_RS16915
uniprot id: A0A127M9F8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1470434:AZF00 RS17375
gene id: 1470434:AZF00_RS17375
uniprot id: A0A127M9N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1470434:AZF00 RS08340
gene id: 1470434:AZF00_RS08340
uniprot id: A0A127M545
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1470434:AZF00 RS03485
gene id: 1470434:AZF00_RS03485
uniprot id: A0A127M2G1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1470434:AZF00 RS14945
gene id: 1470434:AZF00_RS14945
uniprot id: A0A127M8L3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.

1470434:AZF00 RS15585
gene id: 1470434:AZF00_RS15585
uniprot id: A0A127M8S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS11165
gene id: 1470434:AZF00_RS11165
uniprot id: A0A127M6F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1470434:AZF00 RS12425
gene id: 1470434:AZF00_RS12425
uniprot id: A0A127M745
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1470434:AZF00 RS16880
gene id: 1470434:AZF00_RS16880
uniprot id: A0A127MB20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS05270
gene id: 1470434:AZF00_RS05270
uniprot id: A0A127M3D5
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1470434:AZF00 RS07755
gene id: 1470434:AZF00_RS07755
uniprot id: A0A127M4P6
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1470434:AZF00 RS15475
gene id: 1470434:AZF00_RS15475
uniprot id: A0A127M8R1
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1470434:AZF00 RS00490
gene id: 1470434:AZF00_RS00490
uniprot id: A0A127M0X5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1470434:AZF00 RS11800
gene id: 1470434:AZF00_RS11800
uniprot id: A0A127M6U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1470434:AZF00 RS13730
gene id: 1470434:AZF00_RS13730
uniprot id: A0A127M7W0
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1470434:AZF00 RS03400
gene id: 1470434:AZF00_RS03400
uniprot id: A0A127M2F9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1470434:AZF00 RS00290
gene id: 1470434:AZF00_RS00290
uniprot id: A0A127M0T2
names: Similarity
messages: Belongs to the YciI family.

1470434:AZF00 RS00680
gene id: 1470434:AZF00_RS00680
uniprot id: A0A127M0Z4
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

1470434:AZF00 RS14385
gene id: 1470434:AZF00_RS14385
uniprot id: A0A127M848
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS04680
gene id: 1470434:AZF00_RS04680
uniprot id: A0A127M334
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1470434:AZF00 RS06550
gene id: 1470434:AZF00_RS06550
uniprot id: A0A127M402
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1470434:AZF00 RS12735
gene id: 1470434:AZF00_RS12735
uniprot id: A0A127M7C3
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS10320
gene id: 1470434:AZF00_RS10320
uniprot id: A0A127M614
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1470434:AZF00 RS11485
gene id: 1470434:AZF00_RS11485
uniprot id: A0A127M6N7
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1470434:AZF00 RS03660
gene id: 1470434:AZF00_RS03660
uniprot id: A0A127M2K5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1470434:AZF00 RS15495
gene id: 1470434:AZF00_RS15495
uniprot id: A0A127M8M4
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1470434:AZF00 RS03780
gene id: 1470434:AZF00_RS03780
uniprot id: A0A127M2L7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1470434:AZF00 RS05030
gene id: 1470434:AZF00_RS05030
uniprot id: A0A127M390
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS00020
gene id: 1470434:AZF00_RS00020
uniprot id: A0A127M0N2
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS07415
gene id: 1470434:AZF00_RS07415
uniprot id: A0A127M4H8
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1470434:AZF00 RS17765
gene id: 1470434:AZF00_RS17765
uniprot id: A0A127M9V5
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1470434:AZF00 RS16515
gene id: 1470434:AZF00_RS16515
uniprot id: A0A127M9C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1470434:AZF00 RS05655
gene id: 1470434:AZF00_RS05655
uniprot id: A0A127M3H7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

1470434:AZF00 RS02165
gene id: 1470434:AZF00_RS02165
uniprot id: A0A127M1S4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1470434:AZF00 RS16405
gene id: 1470434:AZF00_RS16405
uniprot id: A0A127M9C1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS05850
gene id: 1470434:AZF00_RS05850
uniprot id: A0A127M3Q8
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1470434:AZF00 RS13105
gene id: 1470434:AZF00_RS13105
uniprot id: A0A127M7H1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1470434:AZF00 RS04460
gene id: 1470434:AZF00_RS04460
uniprot id: A0A127M2Z3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1470434:AZF00 RS01590
gene id: 1470434:AZF00_RS01590
uniprot id: A0A127M1H7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1470434:AZF00 RS04960
gene id: 1470434:AZF00_RS04960
uniprot id: A0A127M384
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1470434:AZF00 RS13760
gene id: 1470434:AZF00_RS13760
uniprot id: A0A127M7V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1470434:AZF00 RS19725
gene id: 1470434:AZF00_RS19725
uniprot id: A0A127M6L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

1470434:AZF00 RS16260
gene id: 1470434:AZF00_RS16260
uniprot id: A0A127M938
names: Caution
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS03405
gene id: 1470434:AZF00_RS03405
uniprot id: A0A127M2E9
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS17855
gene id: 1470434:AZF00_RS17855
uniprot id: A0A127M9X4
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1470434:AZF00 RS01100
gene id: 1470434:AZF00_RS01100
uniprot id: A0A127M178
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1470434:AZF00 RS05990
gene id: 1470434:AZF00_RS05990
uniprot id: A0A127M3R3
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1470434:AZF00 RS08060
gene id: 1470434:AZF00_RS08060
uniprot id: A0A127M4W9
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1470434:AZF00 RS08475
gene id: 1470434:AZF00_RS08475
uniprot id: A0A127M548
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1470434:AZF00 RS10865
gene id: 1470434:AZF00_RS10865
uniprot id: A0A127M6B8
names: Similarity
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.

1470434:AZF00 RS03450
gene id: 1470434:AZF00_RS03450
uniprot id: A0A127M2F8
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1470434:AZF00 RS10630
gene id: 1470434:AZF00_RS10630
uniprot id: A0A127M629
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1470434:AZF00 RS15430
gene id: 1470434:AZF00_RS15430
uniprot id: A0A127M8N9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

1470434:AZF00 RS06520
gene id: 1470434:AZF00_RS06520
uniprot id: A0A127M404
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS02310
gene id: 1470434:AZF00_RS02310
uniprot id: A0A127M1T5
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1470434:AZF00 RS00575
gene id: 1470434:AZF00_RS00575
uniprot id: A0A127M0X8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1470434:AZF00 RS06415
gene id: 1470434:AZF00_RS06415
uniprot id: A0A127M3Y4
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1470434:AZF00 RS17870
gene id: 1470434:AZF00_RS17870
uniprot id: A0A127M9Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

1470434:AZF00 RS09130
gene id: 1470434:AZF00_RS09130
uniprot id: A0A127M5E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1470434:AZF00 RS07890
gene id: 1470434:AZF00_RS07890
uniprot id: A0A127M4R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1470434:AZF00 RS18765
gene id: 1470434:AZF00_RS18765
uniprot id: A0A127MAE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1470434:AZF00 RS03625
gene id: 1470434:AZF00_RS03625
uniprot id: A0A127M2I4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1470434:AZF00 RS06850
gene id: 1470434:AZF00_RS06850
uniprot id: A0A127M467
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1470434:AZF00 RS05905
gene id: 1470434:AZF00_RS05905
uniprot id: A0A127M3S9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1470434:AZF00 RS12600
gene id: 1470434:AZF00_RS12600
uniprot id: A0A127M7B5
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1470434:AZF00 RS12180
gene id: 1470434:AZF00_RS12180
uniprot id: A0A127M719
names: Similarity
messages: Belongs to the Gfa family.

1470434:AZF00 RS14700
gene id: 1470434:AZF00_RS14700
uniprot id: A0A127M8F9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1470434:AZF00 RS14655
gene id: 1470434:AZF00_RS14655
uniprot id: A0A127M886
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1470434:AZF00 RS15440
gene id: 1470434:AZF00_RS15440
uniprot id: A0A127M8N0
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1470434:AZF00 RS06745
gene id: 1470434:AZF00_RS06745
uniprot id: A0A127M449
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1470434:AZF00 RS01225
gene id: 1470434:AZF00_RS01225
uniprot id: A0A127M1A5
names: Similarity
messages: Belongs to the HepT RNase toxin family.

1470434:AZF00 RS08925
gene id: 1470434:AZF00_RS08925
uniprot id: A0A127M5C9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1470434:AZF00 RS04160
gene id: 1470434:AZF00_RS04160
uniprot id: A0A127M2S3
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1470434:AZF00 RS07055
gene id: 1470434:AZF00_RS07055
uniprot id: A0A127M4D3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1470434:AZF00 RS06760
gene id: 1470434:AZF00_RS06760
uniprot id: A0A127M487
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS06645
gene id: 1470434:AZF00_RS06645
uniprot id: A0A127M494
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1470434:AZF00 RS07520
gene id: 1470434:AZF00_RS07520
uniprot id: A0A127M4J4
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS19445
gene id: 1470434:AZF00_RS19445
uniprot id: A0A127M3A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1470434:AZF00 RS09785
gene id: 1470434:AZF00_RS09785
uniprot id: A0A127M5Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1470434:AZF00 RS03695
gene id: 1470434:AZF00_RS03695
uniprot id: A0A127M2J4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1470434:AZF00 RS08240
gene id: 1470434:AZF00_RS08240
uniprot id: A0A127M4W7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1470434:AZF00 RS08860
gene id: 1470434:AZF00_RS08860
uniprot id: A0A127M5G7
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS08655
gene id: 1470434:AZF00_RS08655
uniprot id: A0A127M5A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1470434:AZF00 RS03545
gene id: 1470434:AZF00_RS03545
uniprot id: A0A127M2H9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1470434:AZF00 RS08380
gene id: 1470434:AZF00_RS08380
uniprot id: A0A127M516
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Maintains high levels of reduced glutathione.

1470434:AZF00 RS02255
gene id: 1470434:AZF00_RS02255
uniprot id: A0A127M1S3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1470434:AZF00 RS02180
gene id: 1470434:AZF00_RS02180
uniprot id: A0A127M1R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1470434:AZF00 RS13320
gene id: 1470434:AZF00_RS13320
uniprot id: A0A127M7K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S49 family.
messages: Cell inner membrane

1470434:AZF00 RS05630
gene id: 1470434:AZF00_RS05630
uniprot id: A0A127M3K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1470434:AZF00 RS12375
gene id: 1470434:AZF00_RS12375
uniprot id: A0A127M751
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

1470434:AZF00 RS05810
gene id: 1470434:AZF00_RS05810
uniprot id: A0A127M3K5
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1470434:AZF00 RS08700
gene id: 1470434:AZF00_RS08700
uniprot id: A0A127M559
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1470434:AZF00 RS09540
gene id: 1470434:AZF00_RS09540
uniprot id: A0A127M5P1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1470434:AZF00 RS09830
gene id: 1470434:AZF00_RS09830
uniprot id: A0A127M5S2
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1470434:AZF00 RS05110
gene id: 1470434:AZF00_RS05110
uniprot id: A0A127M3B2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1470434:AZF00 RS05635
gene id: 1470434:AZF00_RS05635
uniprot id: A0A127M3S4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1470434:AZF00 RS17505
gene id: 1470434:AZF00_RS17505
uniprot id: A0A127M9X6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1470434:AZF00 RS13050
gene id: 1470434:AZF00_RS13050
uniprot id: A0A127M7F8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

1470434:AZF00 RS03335
gene id: 1470434:AZF00_RS03335
uniprot id: A0A127M2D5
names: Similarity
messages: Belongs to the GppA/Ppx family.

1470434:AZF00 RS05605
gene id: 1470434:AZF00_RS05605
uniprot id: A0A127M3H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1470434:AZF00 RS02190
gene id: 1470434:AZF00_RS02190
uniprot id: A0A127M1U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1470434:AZF00 RS11835
gene id: 1470434:AZF00_RS11835
uniprot id: A0A127M6Q5
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1470434:AZF00 RS08375
gene id: 1470434:AZF00_RS08375
uniprot id: A0A127M4Z9
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

1470434:AZF00 RS10620
gene id: 1470434:AZF00_RS10620
uniprot id: A0A127M685
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1470434:AZF00 RS03645
gene id: 1470434:AZF00_RS03645
uniprot id: A0A127M2I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1470434:AZF00 RS07870
gene id: 1470434:AZF00_RS07870
uniprot id: A0A127M4Q3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1470434:AZF00 RS18650
gene id: 1470434:AZF00_RS18650
uniprot id: A0A127MAF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1470434:AZF00 RS12990
gene id: 1470434:AZF00_RS12990
uniprot id: A0A127M7D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAN1 family.
messages: Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
messages: Nucleus

1470434:AZF00 RS14760
gene id: 1470434:AZF00_RS14760
uniprot id: A0A127M8A4
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1470434:AZF00 RS07875
gene id: 1470434:AZF00_RS07875
uniprot id: A0A127M4Z1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1470434:AZF00 RS05320
gene id: 1470434:AZF00_RS05320
uniprot id: A0A127M3E6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1470434:AZF00 RS17465
gene id: 1470434:AZF00_RS17465
uniprot id: A0A127M9Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

1470434:AZF00 RS10520
gene id: 1470434:AZF00_RS10520
uniprot id: A0A127M611
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1470434:AZF00 RS02540
gene id: 1470434:AZF00_RS02540
uniprot id: A0A127M1Z5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1470434:AZF00 RS17530
gene id: 1470434:AZF00_RS17530
uniprot id: A0A127M9T5
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1470434:AZF00 RS06845
gene id: 1470434:AZF00_RS06845
uniprot id: A0A127M466
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1470434:AZF00 RS02140
gene id: 1470434:AZF00_RS02140
uniprot id: A0A127MAH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1470434:AZF00 RS15565
gene id: 1470434:AZF00_RS15565
uniprot id: A0A127M8U6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1470434:AZF00 RS13925
gene id: 1470434:AZF00_RS13925
uniprot id: A0A127M7U6
names: Similarity
messages: Belongs to the cytochrome P450 family.

1470434:AZF00 RS09295
gene id: 1470434:AZF00_RS09295
uniprot id: A0A127M5F2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

1470434:AZF00 RS10195
gene id: 1470434:AZF00_RS10195
uniprot id: A0A127M5V7
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS09590
gene id: 1470434:AZF00_RS09590
uniprot id: A0A127M5L5
names: Similarity
messages: Belongs to the DsrF/TusC family.

1470434:AZF00 RS16700
gene id: 1470434:AZF00_RS16700
uniprot id: A0A127M9I8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1470434:AZF00 RS05620
gene id: 1470434:AZF00_RS05620
uniprot id: A0A127M3J9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1470434:AZF00 RS14695
gene id: 1470434:AZF00_RS14695
uniprot id: A0A127M8A0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1470434:AZF00 RS07265
gene id: 1470434:AZF00_RS07265
uniprot id: A0A127M4D8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1470434:AZF00 RS14810
gene id: 1470434:AZF00_RS14810
uniprot id: A0A127M8H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1470434:AZF00 RS02815
gene id: 1470434:AZF00_RS02815
uniprot id: A0A127M247
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS15410
gene id: 1470434:AZF00_RS15410
uniprot id: A0A127M8U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1470434:AZF00 RS11655
gene id: 1470434:AZF00_RS11655
uniprot id: A0A127M6M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1470434:AZF00 RS18610
gene id: 1470434:AZF00_RS18610
uniprot id: A0A127MAC1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1470434:AZF00 RS00545
gene id: 1470434:AZF00_RS00545
uniprot id: A0A127M0Y8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1470434:AZF00 RS11345
gene id: 1470434:AZF00_RS11345
uniprot id: A0A127M6M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1470434:AZF00 RS14505
gene id: 1470434:AZF00_RS14505
uniprot id: A0A127M887
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1470434:AZF00 RS16440
gene id: 1470434:AZF00_RS16440
uniprot id: A0A127M966
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

1470434:AZF00 RS04320
gene id: 1470434:AZF00_RS04320
uniprot id: A0A127M2W0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS16370
gene id: 1470434:AZF00_RS16370
uniprot id: A0A127M979
names: Similarity
messages: Belongs to the peptidase C56 family.

1470434:AZF00 RS04190
gene id: 1470434:AZF00_RS04190
uniprot id: A0A127M2U7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1470434:AZF00 RS16085
gene id: 1470434:AZF00_RS16085
uniprot id: A0A127M953
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS06340
gene id: 1470434:AZF00_RS06340
uniprot id: A0A127M3Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1470434:AZF00 RS17445
gene id: 1470434:AZF00_RS17445
uniprot id: A0A127M9W6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1470434:AZF00 RS07160
gene id: 1470434:AZF00_RS07160
uniprot id: A0A127M4I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1470434:AZF00 RS16460
gene id: 1470434:AZF00_RS16460
uniprot id: A0A127M9D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1470434:AZF00 RS14895
gene id: 1470434:AZF00_RS14895
uniprot id: A0A127M8G2
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1470434:AZF00 RS11100
gene id: 1470434:AZF00_RS11100
uniprot id: A0A127M6E5
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS05625
gene id: 1470434:AZF00_RS05625
uniprot id: A0A127M3J7
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1470434:AZF00 RS17125
gene id: 1470434:AZF00_RS17125
uniprot id: A0A127M9J2
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

1470434:AZF00 RS03590
gene id: 1470434:AZF00_RS03590
uniprot id: A0A127M2J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1470434:AZF00 RS01620
gene id: 1470434:AZF00_RS01620
uniprot id: A0A127M1H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1470434:AZF00 RS10045
gene id: 1470434:AZF00_RS10045
uniprot id: A0A127M5W9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS10295
gene id: 1470434:AZF00_RS10295
uniprot id: A0A127M5Y6
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1470434:AZF00 RS07850
gene id: 1470434:AZF00_RS07850
uniprot id: A0A127M4W0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase involved in purine salvage.

1470434:AZF00 RS08915
gene id: 1470434:AZF00_RS08915
uniprot id: A0A127M5B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1470434:AZF00 RS12415
gene id: 1470434:AZF00_RS12415
uniprot id: A0A127M772
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1470434:AZF00 RS12555
gene id: 1470434:AZF00_RS12555
uniprot id: A0A127M777
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1470434:AZF00 RS16230
gene id: 1470434:AZF00_RS16230
uniprot id: A0A127M924
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

1470434:AZF00 RS16645
gene id: 1470434:AZF00_RS16645
uniprot id: A0A127M9A3
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1470434:AZF00 RS09650
gene id: 1470434:AZF00_RS09650
uniprot id: A0A127M5M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1470434:AZF00 RS06335
gene id: 1470434:AZF00_RS06335
uniprot id: A0A127M3V9
names: Similarity
messages: Belongs to the aspartokinase family.

1470434:AZF00 RS10855
gene id: 1470434:AZF00_RS10855
uniprot id: A0A127M693
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1470434:AZF00 RS01110
gene id: 1470434:AZF00_RS01110
uniprot id: A0A127M172
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1470434:AZF00 RS12470
gene id: 1470434:AZF00_RS12470
uniprot id: A0A127M771
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1470434:AZF00 RS05295
gene id: 1470434:AZF00_RS05295
uniprot id: A0A127M3G0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1470434:AZF00 RS10515
gene id: 1470434:AZF00_RS10515
uniprot id: A0A127M660
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1470434:AZF00 RS01205
gene id: 1470434:AZF00_RS01205
uniprot id: A0A127M196
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1470434:AZF00 RS07585
gene id: 1470434:AZF00_RS07585
uniprot id: A0A127M4L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1470434:AZF00 RS14535
gene id: 1470434:AZF00_RS14535
uniprot id: A0A127M8B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1470434:AZF00 RS10590
gene id: 1470434:AZF00_RS10590
uniprot id: A0A127M658
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS02490
gene id: 1470434:AZF00_RS02490
uniprot id: A0A127M1X7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1470434:AZF00 RS16895
gene id: 1470434:AZF00_RS16895
uniprot id: A0A127M9E9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1470434:AZF00 RS16415
gene id: 1470434:AZF00_RS16415
uniprot id: A0A127M967
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1470434:AZF00 RS07280
gene id: 1470434:AZF00_RS07280
uniprot id: A0A127MAM3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1470434:AZF00 RS01850
gene id: 1470434:AZF00_RS01850
uniprot id: A0A127M1L9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1470434:AZF00 RS16315
gene id: 1470434:AZF00_RS16315
uniprot id: A0A127M9B3
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1470434:AZF00 RS06175
gene id: 1470434:AZF00_RS06175
uniprot id: A0A127M3S5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1470434:AZF00 RS14995
gene id: 1470434:AZF00_RS14995
uniprot id: A0A127M8D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1470434:AZF00 RS02135
gene id: 1470434:AZF00_RS02135
uniprot id: A0A127M1T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1470434:AZF00 RS15400
gene id: 1470434:AZF00_RS15400
uniprot id: A0A127M8R5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1470434:AZF00 RS12430
gene id: 1470434:AZF00_RS12430
uniprot id: A0A127M764
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1470434:AZF00 RS12495
gene id: 1470434:AZF00_RS12495
uniprot id: A0A127M775
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1470434:AZF00 RS10935
gene id: 1470434:AZF00_RS10935
uniprot id: A0A127M6A9
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1470434:AZF00 RS02780
gene id: 1470434:AZF00_RS02780
uniprot id: A0A127M242
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1470434:AZF00 RS12715
gene id: 1470434:AZF00_RS12715
uniprot id: A0A127M796
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1470434:AZF00 RS03610
gene id: 1470434:AZF00_RS03610
uniprot id: A0A127M2I3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

1470434:AZF00 RS15515
gene id: 1470434:AZF00_RS15515
uniprot id: A0A127M8P6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1470434:AZF00 RS01570
gene id: 1470434:AZF00_RS01570
uniprot id: A0A127M1H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1470434:AZF00 RS14740
gene id: 1470434:AZF00_RS14740
uniprot id: A0A127M888
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

1470434:AZF00 RS12325
gene id: 1470434:AZF00_RS12325
uniprot id: A0A127M736
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1470434:AZF00 RS16735
gene id: 1470434:AZF00_RS16735
uniprot id: A0A127M9I9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1470434:AZF00 RS12010
gene id: 1470434:AZF00_RS12010
uniprot id: A0A127M6W6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1470434:AZF00 RS04940
gene id: 1470434:AZF00_RS04940
uniprot id: A0A127M398
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1470434:AZF00 RS09790
gene id: 1470434:AZF00_RS09790
uniprot id: A0A127M5U3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1470434:AZF00 RS18715
gene id: 1470434:AZF00_RS18715
uniprot id: A0A127MAD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1470434:AZF00 RS07275
gene id: 1470434:AZF00_RS07275
uniprot id: A0A127M4K3
names: Similarity
messages: Belongs to the peptidase M18 family.

1470434:AZF00 RS04010
gene id: 1470434:AZF00_RS04010
uniprot id: A0A127M2T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS14850
gene id: 1470434:AZF00_RS14850
uniprot id: A0A127M8A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

1470434:AZF00 RS04310
gene id: 1470434:AZF00_RS04310
uniprot id: A0A127M2V1
names: Similarity
messages: Belongs to the glutamate synthase family.

1470434:AZF00 RS13245
gene id: 1470434:AZF00_RS13245
uniprot id: A0A127MAU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

1470434:AZF00 RS05885
gene id: 1470434:AZF00_RS05885
uniprot id: A0A127M3P1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1470434:AZF00 RS09795
gene id: 1470434:AZF00_RS09795
uniprot id: A0A127M5R2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1470434:AZF00 RS06675
gene id: 1470434:AZF00_RS06675
uniprot id: A0A127M462
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1470434:AZF00 RS01530
gene id: 1470434:AZF00_RS01530
uniprot id: A0A127M1F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1470434:AZF00 RS05830
gene id: 1470434:AZF00_RS05830
uniprot id: A0A127M3M5
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

1470434:AZF00 RS17405
gene id: 1470434:AZF00_RS17405
uniprot id: A0A127M9X3
names: Similarity
messages: Belongs to the UPF0235 family.

1470434:AZF00 RS03845
gene id: 1470434:AZF00_RS03845
uniprot id: A0A127M2M7
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1470434:AZF00 RS01390
gene id: 1470434:AZF00_RS01390
uniprot id: A0A127M1E2
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS09875
gene id: 1470434:AZF00_RS09875
uniprot id: A0A127M5W3
names: Similarity
messages: Belongs to the CinA family.

1470434:AZF00 RS01125
gene id: 1470434:AZF00_RS01125
uniprot id: A0A127M189
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1470434:AZF00 RS06825
gene id: 1470434:AZF00_RS06825
uniprot id: A0A127M4A3
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1470434:AZF00 RS01020
gene id: 1470434:AZF00_RS01020
uniprot id: A0A127M181
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1470434:AZF00 RS15050
gene id: 1470434:AZF00_RS15050
uniprot id: A0A127M8I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1470434:AZF00 RS16455
gene id: 1470434:AZF00_RS16455
uniprot id: A0A127M969
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1470434:AZF00 RS05470
gene id: 1470434:AZF00_RS05470
uniprot id: A0A127M3H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS02070
gene id: 1470434:AZF00_RS02070
uniprot id: A0A127M1T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1470434:AZF00 RS10180
gene id: 1470434:AZF00_RS10180
uniprot id: A0A127M609
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1470434:AZF00 RS06670
gene id: 1470434:AZF00_RS06670
uniprot id: A0A127M459
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1470434:AZF00 RS14855
gene id: 1470434:AZF00_RS14855
uniprot id: A0A127M8C6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1470434:AZF00 RS10585
gene id: 1470434:AZF00_RS10585
uniprot id: A0A127M625
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS02550
gene id: 1470434:AZF00_RS02550
uniprot id: A0A127M1Y7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1470434:AZF00 RS01575
gene id: 1470434:AZF00_RS01575
uniprot id: A0A127M1F0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1470434:AZF00 RS13690
gene id: 1470434:AZF00_RS13690
uniprot id: A0A127M7Q8
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

1470434:AZF00 RS09720
gene id: 1470434:AZF00_RS09720
uniprot id: A0A127M5M7
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1470434:AZF00 RS10495
gene id: 1470434:AZF00_RS10495
uniprot id: A0A127M639
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS06715
gene id: 1470434:AZF00_RS06715
uniprot id: A0A127M433
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS08645
gene id: 1470434:AZF00_RS08645
uniprot id: A0A127M562
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1470434:AZF00 RS01880
gene id: 1470434:AZF00_RS01880
uniprot id: A0A127M1N8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1470434:AZF00 RS15040
gene id: 1470434:AZF00_RS15040
uniprot id: A0A127M8H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1470434:AZF00 RS11995
gene id: 1470434:AZF00_RS11995
uniprot id: A0A127M6Y7
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1470434:AZF00 RS12745
gene id: 1470434:AZF00_RS12745
uniprot id: A0A127M7A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1470434:AZF00 RS01350
gene id: 1470434:AZF00_RS01350
uniprot id: A0A127M1D2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

1470434:AZF00 RS06750
gene id: 1470434:AZF00_RS06750
uniprot id: A0A127M4B4
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1470434:AZF00 RS01540
gene id: 1470434:AZF00_RS01540
uniprot id: A0A127M1G8
names: Similarity
messages: Belongs to the peptidase S41A family.

1470434:AZF00 RS06465
gene id: 1470434:AZF00_RS06465
uniprot id: A0A127M3Z4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1470434:AZF00 RS16430
gene id: 1470434:AZF00_RS16430
uniprot id: A0A127M992
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1470434:AZF00 RS07970
gene id: 1470434:AZF00_RS07970
uniprot id: A0A127M4S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1470434:AZF00 RS17695
gene id: 1470434:AZF00_RS17695
uniprot id: A0A127MB22
names: Similarity
messages: Belongs to the UPF0758 family.

1470434:AZF00 RS11710
gene id: 1470434:AZF00_RS11710
uniprot id: A0A127M6T6
names: Similarity
messages: Belongs to the UPF0145 family.

1470434:AZF00 RS15930
gene id: 1470434:AZF00_RS15930
uniprot id: A0A127M930
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1470434:AZF00 RS09945
gene id: 1470434:AZF00_RS09945
uniprot id: A0A127M5W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1470434:AZF00 RS10415
gene id: 1470434:AZF00_RS10415
uniprot id: A0A127M5Z3
names: Similarity
messages: Belongs to the asparaginase 1 family.

1470434:AZF00 RS03220
gene id: 1470434:AZF00_RS03220
uniprot id: A0A127M2B6
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1470434:AZF00 RS06980
gene id: 1470434:AZF00_RS06980
uniprot id: A0A127M498
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS09420
gene id: 1470434:AZF00_RS09420
uniprot id: A0A127M5Q1
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1470434:AZF00 RS05260
gene id: 1470434:AZF00_RS05260
uniprot id: A0A127M3D4
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS05580
gene id: 1470434:AZF00_RS05580
uniprot id: A0A127M3K3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1470434:AZF00 RS01940
gene id: 1470434:AZF00_RS01940
uniprot id: A0A127M1M2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1470434:AZF00 RS03290
gene id: 1470434:AZF00_RS03290
uniprot id: A0A127M2C7
names: Function
names: Subunit
messages: Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins.
messages: Homodimer.

1470434:AZF00 RS10490
gene id: 1470434:AZF00_RS10490
uniprot id: A0A127M667
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1470434:AZF00 RS12420
gene id: 1470434:AZF00_RS12420
uniprot id: A0A127MAV3
names: Subcellular Location Annotation
messages: Cytoplasm

1470434:AZF00 RS01690
gene id: 1470434:AZF00_RS01690
uniprot id: A0A127M1J5
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1470434:AZF00 RS17710
gene id: 1470434:AZF00_RS17710
uniprot id: A0A127M9U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1470434:AZF00 RS07435
gene id: 1470434:AZF00_RS07435
uniprot id: A0A127M4I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1470434:AZF00 RS01345
gene id: 1470434:AZF00_RS01345
uniprot id: A0A127M1E5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1470434:AZF00 RS01855
gene id: 1470434:AZF00_RS01855
uniprot id: A0A127M1M6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1470434:AZF00 RS16785
gene id: 1470434:AZF00_RS16785
uniprot id: A0A127M9C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS04180
gene id: 1470434:AZF00_RS04180
uniprot id: A0A127M2U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1470434:AZF00 RS04270
gene id: 1470434:AZF00_RS04270
uniprot id: A0A127M2U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1470434:AZF00 RS03520
gene id: 1470434:AZF00_RS03520
uniprot id: A0A127M2G3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1470434:AZF00 RS01995
gene id: 1470434:AZF00_RS01995
uniprot id: A0A127M1N9
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1470434:AZF00 RS07220
gene id: 1470434:AZF00_RS07220
uniprot id: A0A127M4F5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1470434:AZF00 RS13040
gene id: 1470434:AZF00_RS13040
uniprot id: A0A127M7J3
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1470434:AZF00 RS16910
gene id: 1470434:AZF00_RS16910
uniprot id: A0A127M9J1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1470434:AZF00 RS07860
gene id: 1470434:AZF00_RS07860
uniprot id: A0A127M4R4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1470434:AZF00 RS04455
gene id: 1470434:AZF00_RS04455
uniprot id: A0A127M2X0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1470434:AZF00 RS01560
gene id: 1470434:AZF00_RS01560
uniprot id: A0A127M1I7
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1470434:AZF00 RS05915
gene id: 1470434:AZF00_RS05915
uniprot id: A0A127M3M6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1470434:AZF00 RS03815
gene id: 1470434:AZF00_RS03815
uniprot id: A0A127MAM7
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1470434:AZF00 RS00105
gene id: 1470434:AZF00_RS00105
uniprot id: A0A127M0Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Membrane

1470434:AZF00 RS19565
gene id: 1470434:AZF00_RS19565
uniprot id: A0A127M259
names: Similarity
messages: Belongs to the rubredoxin family.

1470434:AZF00 RS18250
gene id: 1470434:AZF00_RS18250
uniprot id: A0A127MAB3
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS10650
gene id: 1470434:AZF00_RS10650
uniprot id: A0A127M686
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1470434:AZF00 RS11465
gene id: 1470434:AZF00_RS11465
uniprot id: A0A127M6M0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1470434:AZF00 RS04215
gene id: 1470434:AZF00_RS04215
uniprot id: A0A127M2T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1470434:AZF00 RS01025
gene id: 1470434:AZF00_RS01025
uniprot id: A0A127MAN9
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1470434:AZF00 RS05700
gene id: 1470434:AZF00_RS05700
uniprot id: A0A127MAN4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1470434:AZF00 RS15015
gene id: 1470434:AZF00_RS15015
uniprot id: A0A127M8D8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS00990
gene id: 1470434:AZF00_RS00990
uniprot id: A0A127M156
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1470434:AZF00 RS17525
gene id: 1470434:AZF00_RS17525
uniprot id: A0A127M9T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

1470434:AZF00 RS05645
gene id: 1470434:AZF00_RS05645
uniprot id: A0A127M3N1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1470434:AZF00 RS00005
gene id: 1470434:AZF00_RS00005
uniprot id: A0A127MAN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

1470434:AZF00 RS07240
gene id: 1470434:AZF00_RS07240
uniprot id: A0A127M4E4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1470434:AZF00 RS11610
gene id: 1470434:AZF00_RS11610
uniprot id: A0A127M6R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1470434:AZF00 RS06775
gene id: 1470434:AZF00_RS06775
uniprot id: A0A127M477
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1470434:AZF00 RS11660
gene id: 1470434:AZF00_RS11660
uniprot id: A0A127M6S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1470434:AZF00 RS11665
gene id: 1470434:AZF00_RS11665
uniprot id: A0A127M6R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1470434:AZF00 RS13440
gene id: 1470434:AZF00_RS13440
uniprot id: A0A127M7P9
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1470434:AZF00 RS10445
gene id: 1470434:AZF00_RS10445
uniprot id: A0A127M650
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1470434:AZF00 RS14765
gene id: 1470434:AZF00_RS14765
uniprot id: A0A127M8J0
names: Subcellular Location Annotation
messages: Cytoplasm

1470434:AZF00 RS14450
gene id: 1470434:AZF00_RS14450
uniprot id: A0A127M861
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1470434:AZF00 RS12475
gene id: 1470434:AZF00_RS12475
uniprot id: A0A127M776
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1470434:AZF00 RS07845
gene id: 1470434:AZF00_RS07845
uniprot id: A0A127M4P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1470434:AZF00 RS09835
gene id: 1470434:AZF00_RS09835
uniprot id: A0A127M5U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1470434:AZF00 RS00615
gene id: 1470434:AZF00_RS00615
uniprot id: A0A127M0Y6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1470434:AZF00 RS13745
gene id: 1470434:AZF00_RS13745
uniprot id: A0A127M7S3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1470434:AZF00 RS10565
gene id: 1470434:AZF00_RS10565
uniprot id: A0A127MAU0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1470434:AZF00 RS18615
gene id: 1470434:AZF00_RS18615
uniprot id: A0A127MAB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1470434:AZF00 RS12540
gene id: 1470434:AZF00_RS12540
uniprot id: A0A127M766
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1470434:AZF00 RS02105
gene id: 1470434:AZF00_RS02105
uniprot id: A0A127M1R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1470434:AZF00 RS17865
gene id: 1470434:AZF00_RS17865
uniprot id: A0A127M9X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1470434:AZF00 RS01785
gene id: 1470434:AZF00_RS01785
uniprot id: A0A127M1J1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1470434:AZF00 RS05080
gene id: 1470434:AZF00_RS05080
uniprot id: A0A127M3A5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1470434:AZF00 RS10135
gene id: 1470434:AZF00_RS10135
uniprot id: A0A127M5T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1470434:AZF00 RS05900
gene id: 1470434:AZF00_RS05900
uniprot id: A0A127M3R8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1470434:AZF00 RS12335
gene id: 1470434:AZF00_RS12335
uniprot id: A0A127M738
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1470434:AZF00 RS05865
gene id: 1470434:AZF00_RS05865
uniprot id: A0A127M3L7
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

1470434:AZF00 RS09515
gene id: 1470434:AZF00_RS09515
uniprot id: A0A127M5J8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1470434:AZF00 RS17070
gene id: 1470434:AZF00_RS17070
uniprot id: A0A127MAZ6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1470434:AZF00 RS06810
gene id: 1470434:AZF00_RS06810
uniprot id: A0A127M491
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1470434:AZF00 RS00265
gene id: 1470434:AZF00_RS00265
uniprot id: A0A127M0T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1470434:AZF00 RS11515
gene id: 1470434:AZF00_RS11515
uniprot id: A0A127M6R4
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1470434:AZF00 RS05090
gene id: 1470434:AZF00_RS05090
uniprot id: A0A127M397
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1470434:AZF00 RS03940
gene id: 1470434:AZF00_RS03940
uniprot id: A0A127M2P4
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1470434:AZF00 RS15755
gene id: 1470434:AZF00_RS15755
uniprot id: A0A127M8V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

1470434:AZF00 RS07665
gene id: 1470434:AZF00_RS07665
uniprot id: A0A127M4N6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1470434:AZF00 RS14670
gene id: 1470434:AZF00_RS14670
uniprot id: A0A127M8B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

1470434:AZF00 RS02440
gene id: 1470434:AZF00_RS02440
uniprot id: A0A127M1W7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1470434:AZF00 RS14245
gene id: 1470434:AZF00_RS14245
uniprot id: A0A127M810
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1470434:AZF00 RS15415
gene id: 1470434:AZF00_RS15415
uniprot id: A0A127M8Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

1470434:AZF00 RS04885
gene id: 1470434:AZF00_RS04885
uniprot id: A0A127MAM9
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1470434:AZF00 RS09840
gene id: 1470434:AZF00_RS09840
uniprot id: A0A127M5R3
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

1470434:AZF00 RS02335
gene id: 1470434:AZF00_RS02335
uniprot id: A0A127M1U9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1470434:AZF00 RS09150
gene id: 1470434:AZF00_RS09150
uniprot id: A0A127M5L0
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS09975
gene id: 1470434:AZF00_RS09975
uniprot id: A0A127M5V5
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS18620
gene id: 1470434:AZF00_RS18620
uniprot id: A0A127MAB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1470434:AZF00 RS07950
gene id: 1470434:AZF00_RS07950
uniprot id: A0A127M4X7
names: Subcellular Location Annotation
messages: Membrane

1470434:AZF00 RS02315
gene id: 1470434:AZF00_RS02315
uniprot id: A0A127M1T8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1470434:AZF00 RS14415
gene id: 1470434:AZF00_RS14415
uniprot id: A0A127M855
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1470434:AZF00 RS00865
gene id: 1470434:AZF00_RS00865
uniprot id: A0A127M151
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1470434:AZF00 RS07775
gene id: 1470434:AZF00_RS07775
uniprot id: A0A127M4Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1470434:AZF00 RS16425
gene id: 1470434:AZF00_RS16425
uniprot id: A0A127M990
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1470434:AZF00 RS17715
gene id: 1470434:AZF00_RS17715
uniprot id: A0A127M9V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

1470434:AZF00 RS06725
gene id: 1470434:AZF00_RS06725
uniprot id: A0A127M468
names: Similarity
messages: Belongs to the type III secretion exporter family.

1470434:AZF00 RS05930
gene id: 1470434:AZF00_RS05930
uniprot id: A0A127M3P5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

1470434:AZF00 RS02115
gene id: 1470434:AZF00_RS02115
uniprot id: A0A127M1Q9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1470434:AZF00 RS17365
gene id: 1470434:AZF00_RS17365
uniprot id: A0A127M9N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.