1461582:RZ44 RS04305
gene id: 1461582:RZ44_RS04305
uniprot id: A0A078LYS7
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1461582:RZ44 RS05180
gene id: 1461582:RZ44_RS05180
uniprot id: A0A078M805
names: Similarity
messages: Belongs to the peptidase S49 family.

1461582:RZ44 RS10455
gene id: 1461582:RZ44_RS10455
uniprot id: A0A078MC07
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1461582:RZ44 RS06560
gene id: 1461582:RZ44_RS06560
uniprot id: A0A078M5D8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1461582:RZ44 RS00420
gene id: 1461582:RZ44_RS00420
uniprot id: A0A078LY75
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS02270
gene id: 1461582:RZ44_RS02270
uniprot id: A0A078LW42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1461582:RZ44 RS03920
gene id: 1461582:RZ44_RS03920
uniprot id: A0A078M1E4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1461582:RZ44 RS01830
gene id: 1461582:RZ44_RS01830
uniprot id: A0A078LZ72
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS07280
gene id: 1461582:RZ44_RS07280
uniprot id: A0A078MB19
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1461582:RZ44 RS04805
gene id: 1461582:RZ44_RS04805
uniprot id: A0A078M790
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS05110
gene id: 1461582:RZ44_RS05110
uniprot id: A0A078M3D1
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1461582:RZ44 RS04495
gene id: 1461582:RZ44_RS04495
uniprot id: A0A078M4U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FemABX family.
messages: Cytoplasm

1461582:RZ44 RS00195
gene id: 1461582:RZ44_RS00195
uniprot id: A0A078LY22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1461582:RZ44 RS02570
gene id: 1461582:RZ44_RS02570
uniprot id: A0A078LZV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1461582:RZ44 RS02530
gene id: 1461582:RZ44_RS02530
uniprot id: A0A078LWF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1461582:RZ44 RS02990
gene id: 1461582:RZ44_RS02990
uniprot id: A0A078LX18
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1461582:RZ44 RS05250
gene id: 1461582:RZ44_RS05250
uniprot id: A0A078M3L1
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS10850
gene id: 1461582:RZ44_RS10850
uniprot id: A0A078MCF5
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1461582:RZ44 RS05300
gene id: 1461582:RZ44_RS05300
uniprot id: A0A078M639
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. HrtA family.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex hrt involved in hemin import. Responsible for energy coupling to the transport system.

1461582:RZ44 RS10040
gene id: 1461582:RZ44_RS10040
uniprot id: A0A078MDF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1461582:RZ44 RS04450
gene id: 1461582:RZ44_RS04450
uniprot id: A0A078M261
names: Similarity
messages: Belongs to the CvfB family.

1461582:RZ44 RS08090
gene id: 1461582:RZ44_RS08090
uniprot id: A0A078M4E1
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1461582:RZ44 RS03610
gene id: 1461582:RZ44_RS03610
uniprot id: A0A078M3V4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

1461582:RZ44 RS07410
gene id: 1461582:RZ44_RS07410
uniprot id: A0A078MB77
names: Similarity
messages: Belongs to the pyruvate kinase family.

1461582:RZ44 RS02185
gene id: 1461582:RZ44_RS02185
uniprot id: A0A078LW14
names: Function
names: Similarity
messages: Belongs to the BshC family.
messages: Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.

1461582:RZ44 RS05215
gene id: 1461582:RZ44_RS05215
uniprot id: A0A078M831
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1461582:RZ44 RS01420
gene id: 1461582:RZ44_RS01420
uniprot id: A0A078M1C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS09885
gene id: 1461582:RZ44_RS09885
uniprot id: A0A078MD68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1461582:RZ44 RS06450
gene id: 1461582:RZ44_RS06450
uniprot id: A0A078M9Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1461582:RZ44 RS08935
gene id: 1461582:RZ44_RS08935
uniprot id: A0A078M9E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1461582:RZ44 RS03670
gene id: 1461582:RZ44_RS03670
uniprot id: A0A078LXT8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1461582:RZ44 RS02965
gene id: 1461582:RZ44_RS02965
uniprot id: A0A078LX12
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS06465
gene id: 1461582:RZ44_RS06465
uniprot id: A0A078M1X2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1461582:RZ44 RS06625
gene id: 1461582:RZ44_RS06625
uniprot id: A0A078M281
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS07790
gene id: 1461582:RZ44_RS07790
uniprot id: A0A078M7H3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1461582:RZ44 RS00740
gene id: 1461582:RZ44_RS00740
uniprot id: A0A078LYE8
names: Function
messages: May be involved in multidrug export. Transmembrane domains (TMD) form a pore in the cell membrane and the ATP-binding domain (NBD) is responsible for energy generation.

1461582:RZ44 RS01365
gene id: 1461582:RZ44_RS01365
uniprot id: A0A078M331
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Cell membrane
messages: May form a heterooligomeric complex that consists of seven subunits: mnhA1, mnhB1, mnhC1, mnhD1, mnhE1, mnhF1 and mnhG1.
messages: Membrane

1461582:RZ44 RS03815
gene id: 1461582:RZ44_RS03815
uniprot id: A0A078M5R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1461582:RZ44 RS08615
gene id: 1461582:RZ44_RS08615
uniprot id: A0A078M8Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1461582:RZ44 RS04670
gene id: 1461582:RZ44_RS04670
uniprot id: A0A078M704
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1461582:RZ44 RS00990
gene id: 1461582:RZ44_RS00990
uniprot id: A0A078M2I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1461582:RZ44 RS02295
gene id: 1461582:RZ44_RS02295
uniprot id: A0A078LW54
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1461582:RZ44 RS07995
gene id: 1461582:RZ44_RS07995
uniprot id: A0A078M7M3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1461582:RZ44 RS09175
gene id: 1461582:RZ44_RS09175
uniprot id: A0A078M666
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS02770
gene id: 1461582:RZ44_RS02770
uniprot id: A0A078M0C4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1461582:RZ44 RS07605
gene id: 1461582:RZ44_RS07605
uniprot id: A0A078MBJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1461582:RZ44 RS03640
gene id: 1461582:RZ44_RS03640
uniprot id: A0A078M196
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1461582:RZ44 RS00855
gene id: 1461582:RZ44_RS00855
uniprot id: A0A078LV31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1461582:RZ44 RS10010
gene id: 1461582:RZ44_RS10010
uniprot id: A0A078MDD1
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1461582:RZ44 RS02200
gene id: 1461582:RZ44_RS02200
uniprot id: A0A078LW18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell membrane
messages: Essential cell division protein.
messages: Membrane

1461582:RZ44 RS07525
gene id: 1461582:RZ44_RS07525
uniprot id: A0A078M9B4
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1461582:RZ44 RS01400
gene id: 1461582:RZ44_RS01400
uniprot id: A0A078LVG2
names: Similarity
messages: Belongs to the TrpC family.

1461582:RZ44 RS06935
gene id: 1461582:RZ44_RS06935
uniprot id: A0A078M8G3
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1461582:RZ44 RS02710
gene id: 1461582:RZ44_RS02710
uniprot id: A0A078LWN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1461582:RZ44 RS04935
gene id: 1461582:RZ44_RS04935
uniprot id: A0A078M7N0
names: Function
names: Similarity
messages: Belongs to the thioredoxin family.
messages: Component of the thioredoxin-thioredoxin reductase system. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.

1461582:RZ44 RS10715
gene id: 1461582:RZ44_RS10715
uniprot id: A0A078MC68
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.

1461582:RZ44 RS03380
gene id: 1461582:RZ44_RS03380
uniprot id: A0A078M3L5
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1461582:RZ44 RS00515
gene id: 1461582:RZ44_RS00515
uniprot id: A0A078LYB3
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS04015
gene id: 1461582:RZ44_RS04015
uniprot id: A0A078M1L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1461582:RZ44 RS03295
gene id: 1461582:RZ44_RS03295
uniprot id: A0A078M3J4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1461582:RZ44 RS09785
gene id: 1461582:RZ44_RS09785
uniprot id: A0A078MAJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1461582:RZ44 RS02120
gene id: 1461582:RZ44_RS02120
uniprot id: A0A078M1W2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS04210
gene id: 1461582:RZ44_RS04210
uniprot id: A0A078M1U4
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS01165
gene id: 1461582:RZ44_RS01165
uniprot id: A0A078M2L8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Interacts with CtaA.
messages: Membrane

1461582:RZ44 RS06570
gene id: 1461582:RZ44_RS06570
uniprot id: A0A078M5E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS04330
gene id: 1461582:RZ44_RS04330
uniprot id: A0A078M1Y9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

1461582:RZ44 RS09395
gene id: 1461582:RZ44_RS09395
uniprot id: A0A078M9R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS09730
gene id: 1461582:RZ44_RS09730
uniprot id: A0A078MAP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1461582:RZ44 RS06215
gene id: 1461582:RZ44_RS06215
uniprot id: A0A078M7A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1461582:RZ44 RS04130
gene id: 1461582:RZ44_RS04130
uniprot id: A0A078M1R9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1461582:RZ44 RS04315
gene id: 1461582:RZ44_RS04315
uniprot id: A0A078M4J6
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1461582:RZ44 RS02755
gene id: 1461582:RZ44_RS02755
uniprot id: A0A078M2R0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1461582:RZ44 RS02730
gene id: 1461582:RZ44_RS02730
uniprot id: A0A078M029
names: Function
messages: May be involved in multidrug export. Transmembrane domains (TMD) form a pore in the cell membrane and the ATP-binding domain (NBD) is responsible for energy generation.

1461582:RZ44 RS04225
gene id: 1461582:RZ44_RS04225
uniprot id: A0A078M227
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1461582:RZ44 RS02735
gene id: 1461582:RZ44_RS02735
uniprot id: A0A078M4M1
names: Function
messages: May be involved in multidrug export. Transmembrane domains (TMD) form a pore in the cell membrane and the ATP-binding domain (NBD) is responsible for energy generation.

1461582:RZ44 RS06045
gene id: 1461582:RZ44_RS06045
uniprot id: A0A078M4I7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

1461582:RZ44 RS00415
gene id: 1461582:RZ44_RS00415
uniprot id: A0A078LYA0
names: Subcellular Location Annotation
messages: Cytoplasm

1461582:RZ44 RS05015
gene id: 1461582:RZ44_RS05015
uniprot id: A0A078M011
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS06000
gene id: 1461582:RZ44_RS06000
uniprot id: A0A078M945
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1461582:RZ44 RS09655
gene id: 1461582:RZ44_RS09655
uniprot id: A0A078M743
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS08585
gene id: 1461582:RZ44_RS08585
uniprot id: A0A078MD79
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1461582:RZ44 RS08810
gene id: 1461582:RZ44_RS08810
uniprot id: A0A078MBJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1461582:RZ44 RS07520
gene id: 1461582:RZ44_RS07520
uniprot id: A0A078M6V4
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

1461582:RZ44 RS03065
gene id: 1461582:RZ44_RS03065
uniprot id: A0A078M501
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1461582:RZ44 RS00890
gene id: 1461582:RZ44_RS00890
uniprot id: A0A078LYH5
names: Function
messages: May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.

1461582:RZ44 RS08620
gene id: 1461582:RZ44_RS08620
uniprot id: A0A078MD96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1461582:RZ44 RS10370
gene id: 1461582:RZ44_RS10370
uniprot id: A0A078ME19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1461582:RZ44 RS04105
gene id: 1461582:RZ44_RS04105
uniprot id: A0A078M1Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1461582:RZ44 RS04020
gene id: 1461582:RZ44_RS04020
uniprot id: A0A078M633
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1461582:RZ44 RS03975
gene id: 1461582:RZ44_RS03975
uniprot id: A0A078M5Y2
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1461582:RZ44 RS08860
gene id: 1461582:RZ44_RS08860
uniprot id: A0A078MDN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1461582:RZ44 RS01360
gene id: 1461582:RZ44_RS01360
uniprot id: A0A078LYW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS00945
gene id: 1461582:RZ44_RS00945
uniprot id: A0A078M110
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1461582:RZ44 RS03120
gene id: 1461582:RZ44_RS03120
uniprot id: A0A078LX51
names: Function
messages: May be involved in multidrug export. Transmembrane domains (TMD) form a pore in the cell membrane and the ATP-binding domain (NBD) is responsible for energy generation.

1461582:RZ44 RS03445
gene id: 1461582:RZ44_RS03445
uniprot id: A0A078M3N2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1461582:RZ44 RS02820
gene id: 1461582:RZ44_RS02820
uniprot id: A0A078M376
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1461582:RZ44 RS04500
gene id: 1461582:RZ44_RS04500
uniprot id: A0A078M6T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FemABX family.
messages: Cytoplasm

1461582:RZ44 RS00900
gene id: 1461582:RZ44_RS00900
uniprot id: A0A078M0Z4
names: Function
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

1461582:RZ44 RS10605
gene id: 1461582:RZ44_RS10605
uniprot id: A0A078MC91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.
messages: Homodimer and homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

1461582:RZ44 RS05660
gene id: 1461582:RZ44_RS05660
uniprot id: A0A078M401
names: Similarity
messages: Belongs to the isochorismate synthase family.

1461582:RZ44 RS03060
gene id: 1461582:RZ44_RS03060
uniprot id: A0A078M0G1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1461582:RZ44 RS08670
gene id: 1461582:RZ44_RS08670
uniprot id: A0A078M8Z3
names: Similarity
names: Subunit
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.
messages: Homodimer.

1461582:RZ44 RS10265
gene id: 1461582:RZ44_RS10265
uniprot id: A0A078MFY7
names: Function
messages: May be involved in multidrug export. Transmembrane domains (TMD) form a pore in the cell membrane and the ATP-binding domain (NBD) is responsible for energy generation.

1461582:RZ44 RS01525
gene id: 1461582:RZ44_RS01525
uniprot id: A0A078LYS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS06990
gene id: 1461582:RZ44_RS06990
uniprot id: A0A078M8J7
names: Similarity
messages: Belongs to the FBPase class 3 family.

1461582:RZ44 RS04385
gene id: 1461582:RZ44_RS04385
uniprot id: A0A078M6M4
names: Similarity
messages: Belongs to the TelA family.

1461582:RZ44 RS09765
gene id: 1461582:RZ44_RS09765
uniprot id: A0A078M7A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1461582:RZ44 RS10895
gene id: 1461582:RZ44_RS10895
uniprot id: A0A078MCP9
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1461582:RZ44 RS06665
gene id: 1461582:RZ44_RS06665
uniprot id: A0A078M5J1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1461582:RZ44 RS08865
gene id: 1461582:RZ44_RS08865
uniprot id: A0A078MBL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1461582:RZ44 RS10150
gene id: 1461582:RZ44_RS10150
uniprot id: A0A078M7X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

1461582:RZ44 RS03625
gene id: 1461582:RZ44_RS03625
uniprot id: A0A078LXR3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1461582:RZ44 RS10515
gene id: 1461582:RZ44_RS10515
uniprot id: A0A078MBU6
names: Similarity
messages: Belongs to the peptidase M23B family.

1461582:RZ44 RS02210
gene id: 1461582:RZ44_RS02210
uniprot id: A0A078M207
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS05190
gene id: 1461582:RZ44_RS05190
uniprot id: A0A078M5Y8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS06355
gene id: 1461582:RZ44_RS06355
uniprot id: A0A078M9J3
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS05415
gene id: 1461582:RZ44_RS05415
uniprot id: A0A078M682
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS08780
gene id: 1461582:RZ44_RS08780
uniprot id: A0A078M962
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1461582:RZ44 RS04830
gene id: 1461582:RZ44_RS04830
uniprot id: A0A078M2U4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1461582:RZ44 RS07920
gene id: 1461582:RZ44_RS07920
uniprot id: A0A078M7M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1461582:RZ44 RS02445
gene id: 1461582:RZ44_RS02445
uniprot id: A0A078M488
names: Similarity
messages: Belongs to the fabD family.

1461582:RZ44 RS06765
gene id: 1461582:RZ44_RS06765
uniprot id: A0A078M2G6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS10670
gene id: 1461582:RZ44_RS10670
uniprot id: A0A078MCC6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1461582:RZ44 RS10645
gene id: 1461582:RZ44_RS10645
uniprot id: A0A078MC25
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1461582:RZ44 RS06595
gene id: 1461582:RZ44_RS06595
uniprot id: A0A078M7U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FemABX family.
messages: Cytoplasm

1461582:RZ44 RS02590
gene id: 1461582:RZ44_RS02590
uniprot id: A0A078M2I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1461582:RZ44 RS02525
gene id: 1461582:RZ44_RS02525
uniprot id: A0A078M4A9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1461582:RZ44 RS03465
gene id: 1461582:RZ44_RS03465
uniprot id: A0A078M0V0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1461582:RZ44 RS04220
gene id: 1461582:RZ44_RS04220
uniprot id: A0A078LYP3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1461582:RZ44 RS02175
gene id: 1461582:RZ44_RS02175
uniprot id: A0A078LZE0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1461582:RZ44 RS04520
gene id: 1461582:RZ44_RS04520
uniprot id: A0A078M4W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1461582:RZ44 RS06525
gene id: 1461582:RZ44_RS06525
uniprot id: A0A078M5C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1461582:RZ44 RS09455
gene id: 1461582:RZ44_RS09455
uniprot id: A0A078MA51
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS05590
gene id: 1461582:RZ44_RS05590
uniprot id: A0A078M8E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1461582:RZ44 RS10770
gene id: 1461582:RZ44_RS10770
uniprot id: A0A078MGU4
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1461582:RZ44 RS02415
gene id: 1461582:RZ44_RS02415
uniprot id: A0A078M2A4
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1461582:RZ44 RS04795
gene id: 1461582:RZ44_RS04795
uniprot id: A0A078M783
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1461582:RZ44 RS03305
gene id: 1461582:RZ44_RS03305
uniprot id: A0A078M3J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1461582:RZ44 RS06580
gene id: 1461582:RZ44_RS06580
uniprot id: A0A078M9V5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS03275
gene id: 1461582:RZ44_RS03275
uniprot id: A0A078M0W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1461582:RZ44 RS10255
gene id: 1461582:RZ44_RS10255
uniprot id: A0A078MBK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1461582:RZ44 RS05710
gene id: 1461582:RZ44_RS05710
uniprot id: A0A078M0W4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS07075
gene id: 1461582:RZ44_RS07075
uniprot id: A0A078M2U9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1461582:RZ44 RS00700
gene id: 1461582:RZ44_RS00700
uniprot id: A0A078M0U8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

1461582:RZ44 RS03315
gene id: 1461582:RZ44_RS03315
uniprot id: A0A078M588
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1461582:RZ44 RS09680
gene id: 1461582:RZ44_RS09680
uniprot id: A0A078MCX3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS04120
gene id: 1461582:RZ44_RS04120
uniprot id: A0A078M1Z5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1461582:RZ44 RS08555
gene id: 1461582:RZ44_RS08555
uniprot id: A0A078MB71
names: Similarity
names: Subunit
messages: Belongs to the azoreductase type 2 family.
messages: Homotetramer.

1461582:RZ44 RS07725
gene id: 1461582:RZ44_RS07725
uniprot id: A0A078M9V7
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1461582:RZ44 RS04470
gene id: 1461582:RZ44_RS04470
uniprot id: A0A078LZ31
names: Similarity
messages: Belongs to the UPF0355 family.

1461582:RZ44 RS01115
gene id: 1461582:RZ44_RS01115
uniprot id: A0A078M2K5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1461582:RZ44 RS05235
gene id: 1461582:RZ44_RS05235
uniprot id: A0A078M3K9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1461582:RZ44 RS01995
gene id: 1461582:RZ44_RS01995
uniprot id: A0A078LZ56
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS02075
gene id: 1461582:RZ44_RS02075
uniprot id: A0A078M3R2
names: Similarity
messages: Belongs to the UPF0358 family.

1461582:RZ44 RS02095
gene id: 1461582:RZ44_RS02095
uniprot id: A0A078M1U9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Interacts with CtaA.
messages: Membrane

1461582:RZ44 RS06295
gene id: 1461582:RZ44_RS06295
uniprot id: A0A078M4P0
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1461582:RZ44 RS10530
gene id: 1461582:RZ44_RS10530
uniprot id: A0A078MGH8
names: Similarity
messages: Belongs to the UPF0045 family.

1461582:RZ44 RS07910
gene id: 1461582:RZ44_RS07910
uniprot id: A0A078M7I1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1461582:RZ44 RS03810
gene id: 1461582:RZ44_RS03810
uniprot id: A0A078LY35
names: Similarity
messages: Belongs to the GSP E family.

1461582:RZ44 RS07770
gene id: 1461582:RZ44_RS07770
uniprot id: A0A078M9Y5
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS07965
gene id: 1461582:RZ44_RS07965
uniprot id: A0A078M7Q4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.

1461582:RZ44 RS06910
gene id: 1461582:RZ44_RS06910
uniprot id: A0A078MAJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS06225
gene id: 1461582:RZ44_RS06225
uniprot id: A0A078M4W6
names: Similarity
messages: Belongs to the UDPGP type 1 family.

1461582:RZ44 RS10450
gene id: 1461582:RZ44_RS10450
uniprot id: A0A078MGD9
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1461582:RZ44 RS05805
gene id: 1461582:RZ44_RS05805
uniprot id: A0A078M8P5
names: Similarity
messages: Belongs to the DCK/DGK family.

1461582:RZ44 RS07650
gene id: 1461582:RZ44_RS07650
uniprot id: A0A078M771
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS02275
gene id: 1461582:RZ44_RS02275
uniprot id: A0A078LZP9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1461582:RZ44 RS00710
gene id: 1461582:RZ44_RS00710
uniprot id: A0A078LYE3
names: Similarity
messages: Belongs to the asparaginase 1 family.

1461582:RZ44 RS08255
gene id: 1461582:RZ44_RS08255
uniprot id: A0A078MAL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1461582:RZ44 RS03455
gene id: 1461582:RZ44_RS03455
uniprot id: A0A078M117
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1461582:RZ44 RS09750
gene id: 1461582:RZ44_RS09750
uniprot id: A0A078M787
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1461582:RZ44 RS06435
gene id: 1461582:RZ44_RS06435
uniprot id: A0A078M1V7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1461582:RZ44 RS02675
gene id: 1461582:RZ44_RS02675
uniprot id: A0A078M045
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1461582:RZ44 RS01645
gene id: 1461582:RZ44_RS01645
uniprot id: A0A078LVK0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1461582:RZ44 RS00435
gene id: 1461582:RZ44_RS00435
uniprot id: A0A078LUV8
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1461582:RZ44 RS00125
gene id: 1461582:RZ44_RS00125
uniprot id: A0A078M0H3
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1461582:RZ44 RS01370
gene id: 1461582:RZ44_RS01370
uniprot id: A0A078M1B7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1461582:RZ44 RS10815
gene id: 1461582:RZ44_RS10815
uniprot id: A0A078MER3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1461582:RZ44 RS03165
gene id: 1461582:RZ44_RS03165
uniprot id: A0A078M3G7
names: Similarity
messages: Belongs to the SCO1/2 family.

1461582:RZ44 RS00585
gene id: 1461582:RZ44_RS00585
uniprot id: A0A078LUY4
names: Similarity
messages: Belongs to the AB hydrolase superfamily.

1461582:RZ44 RS00305
gene id: 1461582:RZ44_RS00305
uniprot id: A0A078M0L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Set transporter family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS08930
gene id: 1461582:RZ44_RS08930
uniprot id: A0A078MBN6
names: Similarity
messages: Belongs to the ThiD family.

1461582:RZ44 RS07125
gene id: 1461582:RZ44_RS07125
uniprot id: A0A078MAT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for heme-iron. Responsible for the translocation of the substrate across the membrane.

1461582:RZ44 RS10435
gene id: 1461582:RZ44_RS10435
uniprot id: A0A078ME53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1461582:RZ44 RS10420
gene id: 1461582:RZ44_RS10420
uniprot id: A0A078MGC1
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

1461582:RZ44 RS07730
gene id: 1461582:RZ44_RS07730
uniprot id: A0A078M7E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1461582:RZ44 RS10595
gene id: 1461582:RZ44_RS10595
uniprot id: A0A078MEC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS10665
gene id: 1461582:RZ44_RS10665
uniprot id: A0A078MC37
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1461582:RZ44 RS03400
gene id: 1461582:RZ44_RS03400
uniprot id: A0A078M3L9
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1461582:RZ44 RS03720
gene id: 1461582:RZ44_RS03720
uniprot id: A0A078M170
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Fur family.
messages: Cytoplasm

1461582:RZ44 RS04095
gene id: 1461582:RZ44_RS04095
uniprot id: A0A078M689
names: Function
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1461582:RZ44 RS03420
gene id: 1461582:RZ44_RS03420
uniprot id: A0A078M5C0
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1461582:RZ44 RS09690
gene id: 1461582:RZ44_RS09690
uniprot id: A0A078MEX3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS09665
gene id: 1461582:RZ44_RS09665
uniprot id: A0A078MEW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RpoE family.
messages: Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors.

1461582:RZ44 RS05510
gene id: 1461582:RZ44_RS05510
uniprot id: A0A078M8B9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1461582:RZ44 RS07175
gene id: 1461582:RZ44_RS07175
uniprot id: A0A078MAW4
names: Similarity
messages: Belongs to the peptidase S66 family.

1461582:RZ44 RS08200
gene id: 1461582:RZ44_RS08200
uniprot id: A0A078MAH2
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1461582:RZ44 RS06470
gene id: 1461582:RZ44_RS06470
uniprot id: A0A078M9R0
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1461582:RZ44 RS06555
gene id: 1461582:RZ44_RS06555
uniprot id: A0A078M241
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1461582:RZ44 RS01110
gene id: 1461582:RZ44_RS01110
uniprot id: A0A078LYM6
names: Similarity
messages: Belongs to the ArsC family.

1461582:RZ44 RS06395
gene id: 1461582:RZ44_RS06395
uniprot id: A0A078M9L9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1461582:RZ44 RS01185
gene id: 1461582:RZ44_RS01185
uniprot id: A0A078LYN8
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1461582:RZ44 RS02080
gene id: 1461582:RZ44_RS02080
uniprot id: A0A078LVY0
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS09675
gene id: 1461582:RZ44_RS09675
uniprot id: A0A078MAC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1461582:RZ44 RS03945
gene id: 1461582:RZ44_RS03945
uniprot id: A0A078M1F4
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1461582:RZ44 RS05980
gene id: 1461582:RZ44_RS05980
uniprot id: A0A078M936
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

1461582:RZ44 RS06245
gene id: 1461582:RZ44_RS06245
uniprot id: A0A078M4M2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1461582:RZ44 RS07685
gene id: 1461582:RZ44_RS07685
uniprot id: A0A078M765
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1461582:RZ44 RS09010
gene id: 1461582:RZ44_RS09010
uniprot id: A0A078M9D4
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1461582:RZ44 RS02515
gene id: 1461582:RZ44_RS02515
uniprot id: A0A078LZU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1461582:RZ44 RS05295
gene id: 1461582:RZ44_RS05295
uniprot id: A0A078M859
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. HrtB subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (HrtA), two transmembrane proteins (HrtB) and a solute-binding protein.

1461582:RZ44 RS07850
gene id: 1461582:RZ44_RS07850
uniprot id: A0A078M7F1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

1461582:RZ44 RS07420
gene id: 1461582:RZ44_RS07420
uniprot id: A0A078MB82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell membrane

1461582:RZ44 RS00180
gene id: 1461582:RZ44_RS00180
uniprot id: A0A078LUQ6
names: Function
messages: Repressor of the lactose catabolism operon. Galactose-6-phosphate is the inducer.

1461582:RZ44 RS02645
gene id: 1461582:RZ44_RS02645
uniprot id: A0A078LWK3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1461582:RZ44 RS04410
gene id: 1461582:RZ44_RS04410
uniprot id: A0A078M4P2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1461582:RZ44 RS08815
gene id: 1461582:RZ44_RS08815
uniprot id: A0A078M971
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1461582:RZ44 RS06830
gene id: 1461582:RZ44_RS06830
uniprot id: A0A078M892
names: Similarity
messages: Belongs to the RutC family.

1461582:RZ44 RS08280
gene id: 1461582:RZ44_RS08280
uniprot id: A0A078MCM6
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS06290
gene id: 1461582:RZ44_RS06290
uniprot id: A0A078M7E2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS04185
gene id: 1461582:RZ44_RS04185
uniprot id: A0A078M1T7
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS00685
gene id: 1461582:RZ44_RS00685
uniprot id: A0A078LYE0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1461582:RZ44 RS10680
gene id: 1461582:RZ44_RS10680
uniprot id: A0A078MC46
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1461582:RZ44 RS01560
gene id: 1461582:RZ44_RS01560
uniprot id: A0A078M365
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1461582:RZ44 RS04840
gene id: 1461582:RZ44_RS04840
uniprot id: A0A078M2Z0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1461582:RZ44 RS10035
gene id: 1461582:RZ44_RS10035
uniprot id: A0A078M7Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1461582:RZ44 RS01380
gene id: 1461582:RZ44_RS01380
uniprot id: A0A078LYQ5
names: Function
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1461582:RZ44 RS02040
gene id: 1461582:RZ44_RS02040
uniprot id: A0A078LVW6
names: Similarity
messages: Belongs to the UPF0637 family.

1461582:RZ44 RS08680
gene id: 1461582:RZ44_RS08680
uniprot id: A0A078M8Z7
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. Can also catalyze the epimerization of carbon 2' of dihydroneopterin to dihydromonapterin.

1461582:RZ44 RS08010
gene id: 1461582:RZ44_RS08010
uniprot id: A0A078M7N6
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1461582:RZ44 RS06500
gene id: 1461582:RZ44_RS06500
uniprot id: A0A078M5A5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1461582:RZ44 RS10725
gene id: 1461582:RZ44_RS10725
uniprot id: A0A078MGS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS09375
gene id: 1461582:RZ44_RS09375
uniprot id: A0A078MCA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS06390
gene id: 1461582:RZ44_RS06390
uniprot id: A0A078M1T6
names: Similarity
names: Subunit
messages: Belongs to the azoreductase type 2 family.
messages: Homotetramer.

1461582:RZ44 RS01080
gene id: 1461582:RZ44_RS01080
uniprot id: A0A078LYJ2
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1461582:RZ44 RS01220
gene id: 1461582:RZ44_RS01220
uniprot id: A0A078M158
names: Similarity
messages: Belongs to the aldose epimerase family.

1461582:RZ44 RS03760
gene id: 1461582:RZ44_RS03760
uniprot id: A0A078LY06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS07060
gene id: 1461582:RZ44_RS07060
uniprot id: A0A078M674
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS10460
gene id: 1461582:RZ44_RS10460
uniprot id: A0A078ME65
names: Similarity
messages: Belongs to the GARS family.

1461582:RZ44 RS09140
gene id: 1461582:RZ44_RS09140
uniprot id: A0A078M9G7
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS07120
gene id: 1461582:RZ44_RS07120
uniprot id: A0A078M2V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for heme-iron. Responsible for the translocation of the substrate across the membrane.

1461582:RZ44 RS02705
gene id: 1461582:RZ44_RS02705
uniprot id: A0A078M4K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1461582:RZ44 RS01920
gene id: 1461582:RZ44_RS01920
uniprot id: A0A078LZ21
names: Function
names: Similarity
names: Subunit
messages: A non-essential component of RNA polymerase (RNAP).
messages: Belongs to the RNA polymerase subunit epsilon family.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunit. The core is associated with a delta subunit, and at least one of epsilon or omega. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1461582:RZ44 RS03520
gene id: 1461582:RZ44_RS03520
uniprot id: A0A078LXL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1461582:RZ44 RS06480
gene id: 1461582:RZ44_RS06480
uniprot id: A0A078M4Y7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1461582:RZ44 RS03650
gene id: 1461582:RZ44_RS03650
uniprot id: A0A078M142
names: Similarity
messages: Belongs to the SCO1/2 family.

1461582:RZ44 RS06850
gene id: 1461582:RZ44_RS06850
uniprot id: A0A078M5U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS04745
gene id: 1461582:RZ44_RS04745
uniprot id: A0A078M740
names: Similarity
messages: Belongs to the acyltransferase 3 family.

1461582:RZ44 RS08390
gene id: 1461582:RZ44_RS08390
uniprot id: A0A078M520
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS10585
gene id: 1461582:RZ44_RS10585
uniprot id: A0A078MGM0
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1461582:RZ44 RS03300
gene id: 1461582:RZ44_RS03300
uniprot id: A0A078M0N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1461582:RZ44 RS05090
gene id: 1461582:RZ44_RS05090
uniprot id: A0A078M3A9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS03575
gene id: 1461582:RZ44_RS03575
uniprot id: A0A078LXN5
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1461582:RZ44 RS03755
gene id: 1461582:RZ44_RS03755
uniprot id: A0A078M5N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1461582:RZ44 RS03750
gene id: 1461582:RZ44_RS03750
uniprot id: A0A078M179
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1461582:RZ44 RS01510
gene id: 1461582:RZ44_RS01510
uniprot id: A0A078M355
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1461582:RZ44 RS00475
gene id: 1461582:RZ44_RS00475
uniprot id: A0A078M2B0
names: Function
messages: May be involved in multidrug export. Transmembrane domains (TMD) form a pore in the cell membrane and the ATP-binding domain (NBD) is responsible for energy generation.

1461582:RZ44 RS09925
gene id: 1461582:RZ44_RS09925
uniprot id: A0A078MFD5
names: Function
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1461582:RZ44 RS09570
gene id: 1461582:RZ44_RS09570
uniprot id: A0A078MAG2
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS05060
gene id: 1461582:RZ44_RS05060
uniprot id: A0A078M026
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1461582:RZ44 RS10685
gene id: 1461582:RZ44_RS10685
uniprot id: A0A078MCD6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1461582:RZ44 RS02640
gene id: 1461582:RZ44_RS02640
uniprot id: A0A078M025
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1461582:RZ44 RS00315
gene id: 1461582:RZ44_RS00315
uniprot id: A0A078LY91
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1461582:RZ44 RS02485
gene id: 1461582:RZ44_RS02485
uniprot id: A0A078M2D4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1461582:RZ44 RS02025
gene id: 1461582:RZ44_RS02025
uniprot id: A0A078M3P3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1461582:RZ44 RS07915
gene id: 1461582:RZ44_RS07915
uniprot id: A0A078MA31
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1461582:RZ44 RS09900
gene id: 1461582:RZ44_RS09900
uniprot id: A0A078MFC2
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

1461582:RZ44 RS04535
gene id: 1461582:RZ44_RS04535
uniprot id: A0A078M4X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS00040
gene id: 1461582:RZ44_RS00040
uniprot id: A0A078LXZ0
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

1461582:RZ44 RS06455
gene id: 1461582:RZ44_RS06455
uniprot id: A0A078M1W6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

1461582:RZ44 RS10545
gene id: 1461582:RZ44_RS10545
uniprot id: A0A078M8N3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1461582:RZ44 RS09850
gene id: 1461582:RZ44_RS09850
uniprot id: A0A078MAX8
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS02000
gene id: 1461582:RZ44_RS02000
uniprot id: A0A078M3N4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1461582:RZ44 RS09755
gene id: 1461582:RZ44_RS09755
uniprot id: A0A078MD10
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1461582:RZ44 RS03215
gene id: 1461582:RZ44_RS03215
uniprot id: A0A078M557
names: Function
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.

1461582:RZ44 RS02550
gene id: 1461582:RZ44_RS02550
uniprot id: A0A078M4B8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1461582:RZ44 RS00405
gene id: 1461582:RZ44_RS00405
uniprot id: A0A078M0N1
names: Similarity
messages: Belongs to the LOG family.

1461582:RZ44 RS03910
gene id: 1461582:RZ44_RS03910
uniprot id: A0A078M469
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1461582:RZ44 RS04835
gene id: 1461582:RZ44_RS04835
uniprot id: A0A078M5F6
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS00530
gene id: 1461582:RZ44_RS00530
uniprot id: A0A078M0Q9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1461582:RZ44 RS06270
gene id: 1461582:RZ44_RS06270
uniprot id: A0A078M9D9
names: Similarity
messages: Belongs to the Dps family.

1461582:RZ44 RS00805
gene id: 1461582:RZ44_RS00805
uniprot id: A0A078LV22
names: Similarity
messages: Belongs to the EamA transporter family.

1461582:RZ44 RS09795
gene id: 1461582:RZ44_RS09795
uniprot id: A0A078M7B6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS03655
gene id: 1461582:RZ44_RS03655
uniprot id: A0A078M3X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1461582:RZ44 RS07575
gene id: 1461582:RZ44_RS07575
uniprot id: A0A078M719
names: Similarity
messages: Belongs to the EamA transporter family.

1461582:RZ44 RS05005
gene id: 1461582:RZ44_RS05005
uniprot id: A0A078M5S2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1461582:RZ44 RS00380
gene id: 1461582:RZ44_RS00380
uniprot id: A0A078M0M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS06550
gene id: 1461582:RZ44_RS06550
uniprot id: A0A078M7T2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1461582:RZ44 RS00275
gene id: 1461582:RZ44_RS00275
uniprot id: A0A078M280
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

1461582:RZ44 RS00170
gene id: 1461582:RZ44_RS00170
uniprot id: A0A078M263
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1461582:RZ44 RS09895
gene id: 1461582:RZ44_RS09895
uniprot id: A0A078MB07
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system. Labile antitoxin that binds to cognate MazF toxin and counteracts its endoribonuclease activity.
messages: Belongs to the MazE/EndoAI family.

1461582:RZ44 RS06260
gene id: 1461582:RZ44_RS06260
uniprot id: A0A078M4M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS03500
gene id: 1461582:RZ44_RS03500
uniprot id: A0A078M5E3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS01720
gene id: 1461582:RZ44_RS01720
uniprot id: A0A078LVL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS00960
gene id: 1461582:RZ44_RS00960
uniprot id: A0A078LYI9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1461582:RZ44 RS07860
gene id: 1461582:RZ44_RS07860
uniprot id: A0A078M7F5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS01900
gene id: 1461582:RZ44_RS01900
uniprot id: A0A078M3H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1461582:RZ44 RS10280
gene id: 1461582:RZ44_RS10280
uniprot id: A0A078M887
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1461582:RZ44 RS08140
gene id: 1461582:RZ44_RS08140
uniprot id: A0A078MCF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

1461582:RZ44 RS10620
gene id: 1461582:RZ44_RS10620
uniprot id: A0A078MEE0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1461582:RZ44 RS09920
gene id: 1461582:RZ44_RS09920
uniprot id: A0A078M7J3
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1461582:RZ44 RS08535
gene id: 1461582:RZ44_RS08535
uniprot id: A0A078M8U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

1461582:RZ44 RS09280
gene id: 1461582:RZ44_RS09280
uniprot id: A0A078M9K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1461582:RZ44 RS04820
gene id: 1461582:RZ44_RS04820
uniprot id: A0A078LZM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

1461582:RZ44 RS04815
gene id: 1461582:RZ44_RS04815
uniprot id: A0A078M795
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1461582:RZ44 RS10915
gene id: 1461582:RZ44_RS10915
uniprot id: A0A078MH25
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1461582:RZ44 RS01030
gene id: 1461582:RZ44_RS01030
uniprot id: A0A078LYI2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1461582:RZ44 RS10910
gene id: 1461582:RZ44_RS10910
uniprot id: A0A078M985
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Homodimer; disulfide-linked, upon oxidation. 5 homodimers assemble to form a ring-like decamer.

1461582:RZ44 RS06220
gene id: 1461582:RZ44_RS06220
uniprot id: A0A078M9A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1461582:RZ44 RS08465
gene id: 1461582:RZ44_RS08465
uniprot id: A0A078M568
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1461582:RZ44 RS07815
gene id: 1461582:RZ44_RS07815
uniprot id: A0A078M9Z9
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS01265
gene id: 1461582:RZ44_RS01265
uniprot id: A0A078M323
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS03155
gene id: 1461582:RZ44_RS03155
uniprot id: A0A078LX66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1461582:RZ44 RS00270
gene id: 1461582:RZ44_RS00270
uniprot id: A0A078LY40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1461582:RZ44 RS09310
gene id: 1461582:RZ44_RS09310
uniprot id: A0A078M6E8
names: Similarity
messages: Belongs to the creatininase superfamily.

1461582:RZ44 RS00910
gene id: 1461582:RZ44_RS00910
uniprot id: A0A078LYH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1461582:RZ44 RS09540
gene id: 1461582:RZ44_RS09540
uniprot id: A0A078MEQ9
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

1461582:RZ44 RS03085
gene id: 1461582:RZ44_RS03085
uniprot id: A0A078M0G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

1461582:RZ44 RS10075
gene id: 1461582:RZ44_RS10075
uniprot id: A0A078MDG9
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

1461582:RZ44 RS08625
gene id: 1461582:RZ44_RS08625
uniprot id: A0A078M8Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1461582:RZ44 RS06350
gene id: 1461582:RZ44_RS06350
uniprot id: A0A078M1R0
names: Similarity
messages: Belongs to the UPF0178 family.

1461582:RZ44 RS02470
gene id: 1461582:RZ44_RS02470
uniprot id: A0A078M493
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1461582:RZ44 RS01915
gene id: 1461582:RZ44_RS01915
uniprot id: A0A078M1N2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1461582:RZ44 RS08645
gene id: 1461582:RZ44_RS08645
uniprot id: A0A078M8Y1
names: Function
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1461582:RZ44 RS03480
gene id: 1461582:RZ44_RS03480
uniprot id: A0A078M5D7
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1461582:RZ44 RS08975
gene id: 1461582:RZ44_RS08975
uniprot id: A0A078M9F9
names: Similarity
messages: Belongs to the acyltransferase 3 family.

1461582:RZ44 RS00930
gene id: 1461582:RZ44_RS00930
uniprot id: A0A078LYH4
names: Similarity
names: Subunit
messages: Belongs to the thioredoxin family.
messages: Homodimer; disulfide-linked, upon oxidation. 5 homodimers assemble to form a ring-like decamer.

1461582:RZ44 RS09705
gene id: 1461582:RZ44_RS09705
uniprot id: A0A078MAM7
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1461582:RZ44 RS03680
gene id: 1461582:RZ44_RS03680
uniprot id: A0A078M3Y2
names: PTM
messages: Binds 1 heme c group covalently per subunit.

1461582:RZ44 RS08745
gene id: 1461582:RZ44_RS08745
uniprot id: A0A078MBG0
names: Similarity
messages: Belongs to the ClpA/ClpB family. ClpC subfamily.

1461582:RZ44 RS00440
gene id: 1461582:RZ44_RS00440
uniprot id: A0A078LYA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1461582:RZ44 RS05740
gene id: 1461582:RZ44_RS05740
uniprot id: A0A078M431
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.

1461582:RZ44 RS09835
gene id: 1461582:RZ44_RS09835
uniprot id: A0A078MF72
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1461582:RZ44 RS05285
gene id: 1461582:RZ44_RS05285
uniprot id: A0A078M3M6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1461582:RZ44 RS07330
gene id: 1461582:RZ44_RS07330
uniprot id: A0A078M6L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for heme-iron. Responsible for the translocation of the substrate across the membrane.

1461582:RZ44 RS08805
gene id: 1461582:RZ44_RS08805
uniprot id: A0A078MBI5
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival.

1461582:RZ44 RS03960
gene id: 1461582:RZ44_RS03960
uniprot id: A0A078M1M4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes.
messages: The active site is a redox-active disulfide bond.

1461582:RZ44 RS05935
gene id: 1461582:RZ44_RS05935
uniprot id: A0A078M8Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Membrane

1461582:RZ44 RS03025
gene id: 1461582:RZ44_RS03025
uniprot id: A0A078M4Y8
names: Similarity
messages: Belongs to the carbamate kinase family.

1461582:RZ44 RS02405
gene id: 1461582:RZ44_RS02405
uniprot id: A0A078LWA9
names: Function
names: Similarity
messages: Belongs to the asp23 family.
messages: May play a key role in alkaline pH tolerance.

1461582:RZ44 RS04855
gene id: 1461582:RZ44_RS04855
uniprot id: A0A078M5G7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1461582:RZ44 RS04735
gene id: 1461582:RZ44_RS04735
uniprot id: A0A078M735
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS06545
gene id: 1461582:RZ44_RS06545
uniprot id: A0A078M5D2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1461582:RZ44 RS03050
gene id: 1461582:RZ44_RS03050
uniprot id: A0A078M0N0
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1461582:RZ44 RS03410
gene id: 1461582:RZ44_RS03410
uniprot id: A0A078M3M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1461582:RZ44 RS05845
gene id: 1461582:RZ44_RS05845
uniprot id: A0A078M8R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1461582:RZ44 RS08075
gene id: 1461582:RZ44_RS08075
uniprot id: A0A078M7Y4
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1461582:RZ44 RS05855
gene id: 1461582:RZ44_RS05855
uniprot id: A0A078M161
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS01040
gene id: 1461582:RZ44_RS01040
uniprot id: A0A078M2J1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1461582:RZ44 RS03995
gene id: 1461582:RZ44_RS03995
uniprot id: A0A078M1P3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1461582:RZ44 RS11050
gene id: 1461582:RZ44_RS11050
uniprot id: A0A078M7T5
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1461582:RZ44 RS08260
gene id: 1461582:RZ44_RS08260
uniprot id: A0A078MCL5
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

1461582:RZ44 RS01950
gene id: 1461582:RZ44_RS01950
uniprot id: A0A078M1P7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1461582:RZ44 RS07040
gene id: 1461582:RZ44_RS07040
uniprot id: A0A078M665
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. HrtA family.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex hrt involved in hemin import. Responsible for energy coupling to the transport system.

1461582:RZ44 RS07085
gene id: 1461582:RZ44_RS07085
uniprot id: A0A078M685
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS05400
gene id: 1461582:RZ44_RS05400
uniprot id: A0A078M891
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

1461582:RZ44 RS07015
gene id: 1461582:RZ44_RS07015
uniprot id: A0A078M2T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS03090
gene id: 1461582:RZ44_RS03090
uniprot id: A0A078M0P5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1461582:RZ44 RS07490
gene id: 1461582:RZ44_RS07490
uniprot id: A0A078M991
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS06510
gene id: 1461582:RZ44_RS06510
uniprot id: A0A078M5B5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1461582:RZ44 RS05050
gene id: 1461582:RZ44_RS05050
uniprot id: A0A078M5T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1461582:RZ44 RS05580
gene id: 1461582:RZ44_RS05580
uniprot id: A0A078M6E0
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS06980
gene id: 1461582:RZ44_RS06980
uniprot id: A0A078MAN8
names: Similarity
messages: Belongs to the acyltransferase 3 family.

1461582:RZ44 RS09720
gene id: 1461582:RZ44_RS09720
uniprot id: A0A078M764
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1461582:RZ44 RS03775
gene id: 1461582:RZ44_RS03775
uniprot id: A0A078M191
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1461582:RZ44 RS01540
gene id: 1461582:RZ44_RS01540
uniprot id: A0A078M1E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1461582:RZ44 RS07285
gene id: 1461582:RZ44_RS07285
uniprot id: A0A078M6H0
names: Similarity
messages: Belongs to the universal stress protein A family.

1461582:RZ44 RS03770
gene id: 1461582:RZ44_RS03770
uniprot id: A0A078M412
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1461582:RZ44 RS01140
gene id: 1461582:RZ44_RS01140
uniprot id: A0A078M2L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1461582:RZ44 RS03430
gene id: 1461582:RZ44_RS03430
uniprot id: A0A078M107
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS07155
gene id: 1461582:RZ44_RS07155
uniprot id: A0A078M6B4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS02635
gene id: 1461582:RZ44_RS02635
uniprot id: A0A078LWJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1461582:RZ44 RS02265
gene id: 1461582:RZ44_RS02265
uniprot id: A0A078M3Y7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1461582:RZ44 RS01350
gene id: 1461582:RZ44_RS01350
uniprot id: A0A078LVF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS01840
gene id: 1461582:RZ44_RS01840
uniprot id: A0A078M1K8
names: Similarity
messages: Belongs to the peptidase C56 family.

1461582:RZ44 RS00725
gene id: 1461582:RZ44_RS00725
uniprot id: A0A078M0V2
names: Similarity
messages: Belongs to the AB hydrolase superfamily.

1461582:RZ44 RS00800
gene id: 1461582:RZ44_RS00800
uniprot id: A0A078M0W5
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1461582:RZ44 RS01285
gene id: 1461582:RZ44_RS01285
uniprot id: A0A078LYU5
names: Similarity
messages: Belongs to the HepT RNase toxin family.

1461582:RZ44 RS05850
gene id: 1461582:RZ44_RS05850
uniprot id: A0A078M475
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.

1461582:RZ44 RS06485
gene id: 1461582:RZ44_RS06485
uniprot id: A0A078M1Y5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1461582:RZ44 RS03955
gene id: 1461582:RZ44_RS03955
uniprot id: A0A078M483
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1461582:RZ44 RS10270
gene id: 1461582:RZ44_RS10270
uniprot id: A0A078MBL5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1461582:RZ44 RS03395
gene id: 1461582:RZ44_RS03395
uniprot id: A0A078M0Z8
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1461582:RZ44 RS02020
gene id: 1461582:RZ44_RS02020
uniprot id: A0A078LZ66
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS02500
gene id: 1461582:RZ44_RS02500
uniprot id: A0A078LWE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1461582:RZ44 RS01530
gene id: 1461582:RZ44_RS01530
uniprot id: A0A078LYZ2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1461582:RZ44 RS08460
gene id: 1461582:RZ44_RS08460
uniprot id: A0A078MCZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1461582:RZ44 RS03475
gene id: 1461582:RZ44_RS03475
uniprot id: A0A078LXJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1461582:RZ44 RS04055
gene id: 1461582:RZ44_RS04055
uniprot id: A0A078M668
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS05100
gene id: 1461582:RZ44_RS05100
uniprot id: A0A078M5V1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1461582:RZ44 RS03230
gene id: 1461582:RZ44_RS03230
uniprot id: A0A078M3I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1461582:RZ44 RS06320
gene id: 1461582:RZ44_RS06320
uniprot id: A0A078M1P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1461582:RZ44 RS03075
gene id: 1461582:RZ44_RS03075
uniprot id: A0A078M0P1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1461582:RZ44 RS07785
gene id: 1461582:RZ44_RS07785
uniprot id: A0A078M3U6
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1461582:RZ44 RS03900
gene id: 1461582:RZ44_RS03900
uniprot id: A0A078M5U8
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1461582:RZ44 RS02310
gene id: 1461582:RZ44_RS02310
uniprot id: A0A078LZK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1461582:RZ44 RS03250
gene id: 1461582:RZ44_RS03250
uniprot id: A0A078M0V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS06840
gene id: 1461582:RZ44_RS06840
uniprot id: A0A078M898
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS01600
gene id: 1461582:RZ44_RS01600
uniprot id: A0A078LYT5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1461582:RZ44 RS06960
gene id: 1461582:RZ44_RS06960
uniprot id: A0A078M2S1
names: Cofactor
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

1461582:RZ44 RS04700
gene id: 1461582:RZ44_RS04700
uniprot id: A0A078M583
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpsC/CapA family.
messages: Membrane

1461582:RZ44 RS04775
gene id: 1461582:RZ44_RS04775
uniprot id: A0A078M2R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1461582:RZ44 RS03740
gene id: 1461582:RZ44_RS03740
uniprot id: A0A078M175
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1461582:RZ44 RS04340
gene id: 1461582:RZ44_RS04340
uniprot id: A0A078M267
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS07870
gene id: 1461582:RZ44_RS07870
uniprot id: A0A078MC16
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS07680
gene id: 1461582:RZ44_RS07680
uniprot id: A0A078M9P8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1461582:RZ44 RS03335
gene id: 1461582:RZ44_RS03335
uniprot id: A0A078M0P9
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp.

1461582:RZ44 RS04505
gene id: 1461582:RZ44_RS04505
uniprot id: A0A078LZ49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FemABX family.
messages: Cytoplasm

1461582:RZ44 RS07935
gene id: 1461582:RZ44_RS07935
uniprot id: A0A078M443
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1461582:RZ44 RS06430
gene id: 1461582:RZ44_RS06430
uniprot id: A0A078M9P4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1461582:RZ44 RS01450
gene id: 1461582:RZ44_RS01450
uniprot id: A0A078LVG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0344 family.
messages: Cell membrane

1461582:RZ44 RS07750
gene id: 1461582:RZ44_RS07750
uniprot id: A0A078M7F0
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1461582:RZ44 RS01060
gene id: 1461582:RZ44_RS01060
uniprot id: A0A078LYL5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1461582:RZ44 RS05355
gene id: 1461582:RZ44_RS05355
uniprot id: A0A078M658
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1461582:RZ44 RS02465
gene id: 1461582:RZ44_RS02465
uniprot id: A0A078LZS2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1461582:RZ44 RS08715
gene id: 1461582:RZ44_RS08715
uniprot id: A0A078M919
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

1461582:RZ44 RS10640
gene id: 1461582:RZ44_RS10640
uniprot id: A0A078MEE9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1461582:RZ44 RS02560
gene id: 1461582:RZ44_RS02560
uniprot id: A0A078LZY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.

1461582:RZ44 RS04040
gene id: 1461582:RZ44_RS04040
uniprot id: A0A078M1N9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1461582:RZ44 RS08455
gene id: 1461582:RZ44_RS08455
uniprot id: A0A078M563
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1461582:RZ44 RS03915
gene id: 1461582:RZ44_RS03915
uniprot id: A0A078LY99
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1461582:RZ44 RS08210
gene id: 1461582:RZ44_RS08210
uniprot id: A0A078M4L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS01240
gene id: 1461582:RZ44_RS01240
uniprot id: A0A078M2P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS09725
gene id: 1461582:RZ44_RS09725
uniprot id: A0A078MEZ3
names: Similarity
messages: Belongs to the UPF0340 family.

1461582:RZ44 RS02425
gene id: 1461582:RZ44_RS02425
uniprot id: A0A078M480
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1461582:RZ44 RS08410
gene id: 1461582:RZ44_RS08410
uniprot id: A0A078MAW1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS04140
gene id: 1461582:RZ44_RS04140
uniprot id: A0A078LYL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1461582:RZ44 RS04370
gene id: 1461582:RZ44_RS04370
uniprot id: A0A078LYX0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Forms a 24-polypeptide structural core with octahedral symmetry. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

1461582:RZ44 RS07645
gene id: 1461582:RZ44_RS07645
uniprot id: A0A078M3G6
names: Similarity
messages: Belongs to the universal stress protein A family.

1461582:RZ44 RS01855
gene id: 1461582:RZ44_RS01855
uniprot id: A0A078LVQ0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS08110
gene id: 1461582:RZ44_RS08110
uniprot id: A0A078MAD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1461582:RZ44 RS01405
gene id: 1461582:RZ44_RS01405
uniprot id: A0A078LYQ9
names: Similarity
messages: Belongs to the TrpF family.

1461582:RZ44 RS04770
gene id: 1461582:RZ44_RS04770
uniprot id: A0A078M2R4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family. ParE type 2 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1461582:RZ44 RS10125
gene id: 1461582:RZ44_RS10125
uniprot id: A0A078MBB0
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1461582:RZ44 RS08350
gene id: 1461582:RZ44_RS08350
uniprot id: A0A078M8C5
names: Similarity
messages: Belongs to the arginase family.

1461582:RZ44 RS03255
gene id: 1461582:RZ44_RS03255
uniprot id: A0A078M3I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1461582:RZ44 RS08070
gene id: 1461582:RZ44_RS08070
uniprot id: A0A078MAA9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1461582:RZ44 RS09915
gene id: 1461582:RZ44_RS09915
uniprot id: A0A078MAT7
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).

1461582:RZ44 RS09745
gene id: 1461582:RZ44_RS09745
uniprot id: A0A078MD02
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS04630
gene id: 1461582:RZ44_RS04630
uniprot id: A0A078M531
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1461582:RZ44 RS04360
gene id: 1461582:RZ44_RS04360
uniprot id: A0A078M4L6
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS03560
gene id: 1461582:RZ44_RS03560
uniprot id: A0A078M5G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1461582:RZ44 RS01590
gene id: 1461582:RZ44_RS01590
uniprot id: A0A078M1F1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS02960
gene id: 1461582:RZ44_RS02960
uniprot id: A0A078M4W8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1461582:RZ44 RS06410
gene id: 1461582:RZ44_RS06410
uniprot id: A0A078M565
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

1461582:RZ44 RS01895
gene id: 1461582:RZ44_RS01895
uniprot id: A0A078LZ10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS06445
gene id: 1461582:RZ44_RS06445
uniprot id: A0A078M1W1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1461582:RZ44 RS10315
gene id: 1461582:RZ44_RS10315
uniprot id: A0A078MBS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1461582:RZ44 RS09515
gene id: 1461582:RZ44_RS09515
uniprot id: A0A078MCN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1461582:RZ44 RS01885
gene id: 1461582:RZ44_RS01885
uniprot id: A0A078LZ96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1461582:RZ44 RS09545
gene id: 1461582:RZ44_RS09545
uniprot id: A0A078MAF2
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS09615
gene id: 1461582:RZ44_RS09615
uniprot id: A0A078MEU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1461582:RZ44 RS10900
gene id: 1461582:RZ44_RS10900
uniprot id: A0A078MEX2
names: Similarity
messages: Belongs to the UPF0421 family.

1461582:RZ44 RS05460
gene id: 1461582:RZ44_RS05460
uniprot id: A0A078M697
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS07440
gene id: 1461582:RZ44_RS07440
uniprot id: A0A078M319
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS04145
gene id: 1461582:RZ44_RS04145
uniprot id: A0A078M6B2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1461582:RZ44 RS07135
gene id: 1461582:RZ44_RS07135
uniprot id: A0A078M8Q5
names: Similarity
messages: Belongs to the YjdM family.

1461582:RZ44 RS09065
gene id: 1461582:RZ44_RS09065
uniprot id: A0A078M9E6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS03270
gene id: 1461582:RZ44_RS03270
uniprot id: A0A078LXB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1461582:RZ44 RS05085
gene id: 1461582:RZ44_RS05085
uniprot id: A0A078M5U6
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

1461582:RZ44 RS06240
gene id: 1461582:RZ44_RS06240
uniprot id: A0A078M7C1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1461582:RZ44 RS08755
gene id: 1461582:RZ44_RS08755
uniprot id: A0A078M947
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1461582:RZ44 RS03440
gene id: 1461582:RZ44_RS03440
uniprot id: A0A078M112
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1461582:RZ44 RS02100
gene id: 1461582:RZ44_RS02100
uniprot id: A0A078LZI6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1461582:RZ44 RS03570
gene id: 1461582:RZ44_RS03570
uniprot id: A0A078M169
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1461582:RZ44 RS04045
gene id: 1461582:RZ44_RS04045
uniprot id: A0A078M4C7
names: Subunit
messages: Homodimer; disulfide-linked, upon oxidation. 5 homodimers assemble to form a ring-like decamer.

1461582:RZ44 RS04970
gene id: 1461582:RZ44_RS04970
uniprot id: A0A078M5R3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1461582:RZ44 RS08845
gene id: 1461582:RZ44_RS08845
uniprot id: A0A078M988
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1461582:RZ44 RS05975
gene id: 1461582:RZ44_RS05975
uniprot id: A0A078M1D8
names: Function
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.
messages: Reduces FMN, organic nitro compounds and disulfide DTNB. Involved in maintenance of the cellular redox state and the disulfide stress response.

1461582:RZ44 RS10950
gene id: 1461582:RZ44_RS10950
uniprot id: A0A078LY73
names: Similarity
messages: Belongs to the peptidase C40 family.

1461582:RZ44 RS03705
gene id: 1461582:RZ44_RS03705
uniprot id: A0A078LXX1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1461582:RZ44 RS00480
gene id: 1461582:RZ44_RS00480
uniprot id: A0A078M0P8
names: Function
messages: May be involved in multidrug export. Transmembrane domains (TMD) form a pore in the cell membrane and the ATP-binding domain (NBD) is responsible for energy generation.

1461582:RZ44 RS04765
gene id: 1461582:RZ44_RS04765
uniprot id: A0A078M750
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1461582:RZ44 RS01880
gene id: 1461582:RZ44_RS01880
uniprot id: A0A078LVQ8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

1461582:RZ44 RS06440
gene id: 1461582:RZ44_RS06440
uniprot id: A0A078M4W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1461582:RZ44 RS00245
gene id: 1461582:RZ44_RS00245
uniprot id: A0A078LY34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family. YeeN subfamily.
messages: Cytoplasm

1461582:RZ44 RS10475
gene id: 1461582:RZ44_RS10475
uniprot id: A0A078MGF4
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS00570
gene id: 1461582:RZ44_RS00570
uniprot id: A0A078LYA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1461582:RZ44 RS06475
gene id: 1461582:RZ44_RS06475
uniprot id: A0A078M1X8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1461582:RZ44 RS06255
gene id: 1461582:RZ44_RS06255
uniprot id: A0A078M9C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS03365
gene id: 1461582:RZ44_RS03365
uniprot id: A0A078LXF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1461582:RZ44 RS03310
gene id: 1461582:RZ44_RS03310
uniprot id: A0A078M0P3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1461582:RZ44 RS03125
gene id: 1461582:RZ44_RS03125
uniprot id: A0A078M0R0
names: Function
messages: May be involved in multidrug export. Transmembrane domains (TMD) form a pore in the cell membrane and the ATP-binding domain (NBD) is responsible for energy generation.

1461582:RZ44 RS07045
gene id: 1461582:RZ44_RS07045
uniprot id: A0A078MAQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. HrtB subfamily.
messages: Membrane
messages: Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (HrtA), two transmembrane proteins (HrtB) and a solute-binding protein.

1461582:RZ44 RS06635
gene id: 1461582:RZ44_RS06635
uniprot id: A0A078M584
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1461582:RZ44 RS10660
gene id: 1461582:RZ44_RS10660
uniprot id: A0A078MEF7
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1461582:RZ44 RS02300
gene id: 1461582:RZ44_RS02300
uniprot id: A0A078LZQ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

1461582:RZ44 RS00835
gene id: 1461582:RZ44_RS00835
uniprot id: A0A078LYG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for heme-iron. Responsible for the translocation of the substrate across the membrane.

1461582:RZ44 RS04980
gene id: 1461582:RZ44_RS04980
uniprot id: A0A078M5R6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1461582:RZ44 RS05175
gene id: 1461582:RZ44_RS05175
uniprot id: A0A078M084
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS00840
gene id: 1461582:RZ44_RS00840
uniprot id: A0A078LYH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for heme-iron. Responsible for the translocation of the substrate across the membrane.

1461582:RZ44 RS02480
gene id: 1461582:RZ44_RS02480
uniprot id: A0A078LZV9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1461582:RZ44 RS08085
gene id: 1461582:RZ44_RS08085
uniprot id: A0A078MCC1
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS05135
gene id: 1461582:RZ44_RS05135
uniprot id: A0A078M063
names: Similarity
messages: Belongs to the UPF0173 family.

1461582:RZ44 RS08015
gene id: 1461582:RZ44_RS08015
uniprot id: A0A078M494
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1461582:RZ44 RS03460
gene id: 1461582:RZ44_RS03460
uniprot id: A0A078LXI9
names: Similarity
messages: Belongs to the UPF0473 family.

1461582:RZ44 RS09355
gene id: 1461582:RZ44_RS09355
uniprot id: A0A078M9N9
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1461582:RZ44 RS09620
gene id: 1461582:RZ44_RS09620
uniprot id: A0A078MA99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1461582:RZ44 RS10700
gene id: 1461582:RZ44_RS10700
uniprot id: A0A078MC56
names: Similarity
messages: Belongs to the UPF0311 family.

1461582:RZ44 RS01070
gene id: 1461582:RZ44_RS01070
uniprot id: A0A078M130
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
messages: Cytoplasm

1461582:RZ44 RS07430
gene id: 1461582:RZ44_RS07430
uniprot id: A0A078M318
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1461582:RZ44 RS07600
gene id: 1461582:RZ44_RS07600
uniprot id: A0A078M3B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS09910
gene id: 1461582:RZ44_RS09910
uniprot id: A0A078MD81
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: Positive regulator of sigma-B activity. Non-phosphorylated RsbV binds to RsbW, preventing its association with sigma-B. When phosphorylated, releases RsbW, which is then free to complex with and inactivate sigma-B.

1461582:RZ44 RS02650
gene id: 1461582:RZ44_RS02650
uniprot id: A0A078M032
names: Similarity
messages: Belongs to the ribF family.

1461582:RZ44 RS08690
gene id: 1461582:RZ44_RS08690
uniprot id: A0A078MDE6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1461582:RZ44 RS08215
gene id: 1461582:RZ44_RS08215
uniprot id: A0A078MCJ4
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1461582:RZ44 RS02555
gene id: 1461582:RZ44_RS02555
uniprot id: A0A078LWG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1461582:RZ44 RS04850
gene id: 1461582:RZ44_RS04850
uniprot id: A0A078M2Z2
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1461582:RZ44 RS03510
gene id: 1461582:RZ44_RS03510
uniprot id: A0A078M143
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1461582:RZ44 RS10880
gene id: 1461582:RZ44_RS10880
uniprot id: A0A078MH01
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1461582:RZ44 RS09385
gene id: 1461582:RZ44_RS09385
uniprot id: A0A078M9Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS05075
gene id: 1461582:RZ44_RS05075
uniprot id: A0A078M034
names: Similarity
messages: Belongs to the citrate synthase family.

1461582:RZ44 RS09770
gene id: 1461582:RZ44_RS09770
uniprot id: A0A078MF33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1461582:RZ44 RS00255
gene id: 1461582:RZ44_RS00255
uniprot id: A0A078M0K2
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1461582:RZ44 RS06325
gene id: 1461582:RZ44_RS06325
uniprot id: A0A078M4Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1461582:RZ44 RS05725
gene id: 1461582:RZ44_RS05725
uniprot id: A0A078M8K8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1461582:RZ44 RS04705
gene id: 1461582:RZ44_RS04705
uniprot id: A0A078M2T0
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1461582:RZ44 RS01340
gene id: 1461582:RZ44_RS01340
uniprot id: A0A078M328
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS00300
gene id: 1461582:RZ44_RS00300
uniprot id: A0A078M284
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1461582:RZ44 RS06460
gene id: 1461582:RZ44_RS06460
uniprot id: A0A078M9Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1461582:RZ44 RS02005
gene id: 1461582:RZ44_RS02005
uniprot id: A0A078LVV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1461582:RZ44 RS07865
gene id: 1461582:RZ44_RS07865
uniprot id: A0A078MA14
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1461582:RZ44 RS03580
gene id: 1461582:RZ44_RS03580
uniprot id: A0A078M173
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1461582:RZ44 RS06805
gene id: 1461582:RZ44_RS06805
uniprot id: A0A078M879
names: Function
messages: May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.

1461582:RZ44 RS10885
gene id: 1461582:RZ44_RS10885
uniprot id: A0A078MCP4
names: Similarity
messages: Belongs to the UPF0374 family.

1461582:RZ44 RS04085
gene id: 1461582:RZ44_RS04085
uniprot id: A0A078M4D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1461582:RZ44 RS05620
gene id: 1461582:RZ44_RS05620
uniprot id: A0A078M3Y4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1461582:RZ44 RS09825
gene id: 1461582:RZ44_RS09825
uniprot id: A0A078MAM0
names: Similarity
messages: Belongs to the ThiD family.

1461582:RZ44 RS04440
gene id: 1461582:RZ44_RS04440
uniprot id: A0A078M6P7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS00765
gene id: 1461582:RZ44_RS00765
uniprot id: A0A078LYF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1461582:RZ44 RS07615
gene id: 1461582:RZ44_RS07615
uniprot id: A0A078M3D6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1461582:RZ44 RS04760
gene id: 1461582:RZ44_RS04760
uniprot id: A0A078M5B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS02980
gene id: 1461582:RZ44_RS02980
uniprot id: A0A078M0D3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring.
messages: Homotetramer.

1461582:RZ44 RS06845
gene id: 1461582:RZ44_RS06845
uniprot id: A0A078M5N4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS10870
gene id: 1461582:RZ44_RS10870
uniprot id: A0A078MGZ3
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS00320
gene id: 1461582:RZ44_RS00320
uniprot id: A0A078LY53
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1461582:RZ44 RS07180
gene id: 1461582:RZ44_RS07180
uniprot id: A0A078M6C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1461582:RZ44 RS08675
gene id: 1461582:RZ44_RS08675
uniprot id: A0A078M5L8
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1461582:RZ44 RS03355
gene id: 1461582:RZ44_RS03355
uniprot id: A0A078LXE9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS05515
gene id: 1461582:RZ44_RS05515
uniprot id: A0A078M0M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1461582:RZ44 RS08475
gene id: 1461582:RZ44_RS08475
uniprot id: A0A078MAZ1
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1461582:RZ44 RS08760
gene id: 1461582:RZ44_RS08760
uniprot id: A0A078MBG6
names: Similarity
messages: Belongs to the ycf81 family.

1461582:RZ44 RS06540
gene id: 1461582:RZ44_RS06540
uniprot id: A0A078M7S3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1461582:RZ44 RS04265
gene id: 1461582:RZ44_RS04265
uniprot id: A0A078M6H8
names: Subcellular Location Annotation
messages: Cytoplasm

1461582:RZ44 RS04100
gene id: 1461582:RZ44_RS04100
uniprot id: A0A078LYK2
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1461582:RZ44 RS08095
gene id: 1461582:RZ44_RS08095
uniprot id: A0A078MCC5
names: Caution
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1461582:RZ44 RS02375
gene id: 1461582:RZ44_RS02375
uniprot id: A0A078LZN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1461582:RZ44 RS07940
gene id: 1461582:RZ44_RS07940
uniprot id: A0A078MC48
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1461582:RZ44 RS01665
gene id: 1461582:RZ44_RS01665
uniprot id: A0A078M1G4
names: Subcellular Location Annotation
messages: Cell membrane

1461582:RZ44 RS05520
gene id: 1461582:RZ44_RS05520
uniprot id: A0A078M3V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1461582:RZ44 RS05390
gene id: 1461582:RZ44_RS05390
uniprot id: A0A078M671
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0478 family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS09295
gene id: 1461582:RZ44_RS09295
uniprot id: A0A078M9L4
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1461582:RZ44 RS02880
gene id: 1461582:RZ44_RS02880
uniprot id: A0A078M4U6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1461582:RZ44 RS07370
gene id: 1461582:RZ44_RS07370
uniprot id: A0A078M6P3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1461582:RZ44 RS02715
gene id: 1461582:RZ44_RS02715
uniprot id: A0A078M065
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

1461582:RZ44 RS08145
gene id: 1461582:RZ44_RS08145
uniprot id: A0A078MAF0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1461582:RZ44 RS03260
gene id: 1461582:RZ44_RS03260
uniprot id: A0A078M0M8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1461582:RZ44 RS07655
gene id: 1461582:RZ44_RS07655
uniprot id: A0A078M3H3
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS10960
gene id: 1461582:RZ44_RS10960
uniprot id: A0A078LVJ5
names: Similarity
messages: Belongs to the peptidase M23B family.

1461582:RZ44 RS08480
gene id: 1461582:RZ44_RS08480
uniprot id: A0A078M8K7
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1461582:RZ44 RS03985
gene id: 1461582:RZ44_RS03985
uniprot id: A0A078M496
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1461582:RZ44 RS04250
gene id: 1461582:RZ44_RS04250
uniprot id: A0A078M6H2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.

1461582:RZ44 RS00885
gene id: 1461582:RZ44_RS00885
uniprot id: A0A078LYG8
names: Similarity
messages: Belongs to the IMPACT family.

1461582:RZ44 RS04465
gene id: 1461582:RZ44_RS04465
uniprot id: A0A078M273
names: Similarity
messages: Belongs to the acyltransferase 3 family.

1461582:RZ44 RS05950
gene id: 1461582:RZ44_RS05950
uniprot id: A0A078M4E9
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1461582:RZ44 RS04965
gene id: 1461582:RZ44_RS04965
uniprot id: A0A078M347
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1461582:RZ44 RS08725
gene id: 1461582:RZ44_RS08725
uniprot id: A0A078M913
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1461582:RZ44 RS01465
gene id: 1461582:RZ44_RS01465
uniprot id: A0A078M1D2
names: Function
messages: May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.

1461582:RZ44 RS01355
gene id: 1461582:RZ44_RS01355
uniprot id: A0A078LYQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Membrane

1461582:RZ44 RS00745
gene id: 1461582:RZ44_RS00745
uniprot id: A0A078M2F2
names: Function
messages: May be involved in multidrug export. Transmembrane domains (TMD) form a pore in the cell membrane and the ATP-binding domain (NBD) is responsible for energy generation.

1461582:RZ44 RS09265
gene id: 1461582:RZ44_RS09265
uniprot id: A0A078ME09
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1461582:RZ44 RS07980
gene id: 1461582:RZ44_RS07980
uniprot id: A0A078MA53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1461582:RZ44 RS01870
gene id: 1461582:RZ44_RS01870
uniprot id: A0A078LZ00
names: Similarity
messages: Belongs to the arginase family.

1461582:RZ44 RS04050
gene id: 1461582:RZ44_RS04050
uniprot id: A0A078M1P4
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS02010
gene id: 1461582:RZ44_RS02010
uniprot id: A0A078LZE5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS04950
gene id: 1461582:RZ44_RS04950
uniprot id: A0A078M346
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS06265
gene id: 1461582:RZ44_RS06265
uniprot id: A0A078M1L0
names: Similarity
messages: Belongs to the DtxR/MntR family.

1461582:RZ44 RS10820
gene id: 1461582:RZ44_RS10820
uniprot id: A0A078MCK7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1461582:RZ44 RS07845
gene id: 1461582:RZ44_RS07845
uniprot id: A0A078M7J2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1461582:RZ44 RS03055
gene id: 1461582:RZ44_RS03055
uniprot id: A0A078M3E1
names: Similarity
messages: Belongs to the ketopantoate reductase family.

1461582:RZ44 RS06760
gene id: 1461582:RZ44_RS06760
uniprot id: A0A078MA66
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1461582:RZ44 RS03540
gene id: 1461582:RZ44_RS03540
uniprot id: A0A078M5F3
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS09855
gene id: 1461582:RZ44_RS09855
uniprot id: A0A078MD52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1461582:RZ44 RS09805
gene id: 1461582:RZ44_RS09805
uniprot id: A0A078M7C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1461582:RZ44 RS10285
gene id: 1461582:RZ44_RS10285
uniprot id: A0A078MBE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS06345
gene id: 1461582:RZ44_RS06345
uniprot id: A0A078M4R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS01550
gene id: 1461582:RZ44_RS01550
uniprot id: A0A078LYT1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MecA family.
messages: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
messages: Homodimer.
messages: The N-terminal domain probably binds unfolded/aggregated proteins; the C-terminal domain interacts with ClpC.

1461582:RZ44 RS10555
gene id: 1461582:RZ44_RS10555
uniprot id: A0A078M8P3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1461582:RZ44 RS04915
gene id: 1461582:RZ44_RS04915
uniprot id: A0A078M329
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1461582:RZ44 RS01035
gene id: 1461582:RZ44_RS01035
uniprot id: A0A078LYK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1461582:RZ44 RS02750
gene id: 1461582:RZ44_RS02750
uniprot id: A0A078M4M6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1461582:RZ44 RS04435
gene id: 1461582:RZ44_RS04435
uniprot id: A0A078M251
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1461582:RZ44 RS01000
gene id: 1461582:RZ44_RS01000
uniprot id: A0A078LYH9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1461582:RZ44 RS09340
gene id: 1461582:RZ44_RS09340
uniprot id: A0A078M9N0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS09840
gene id: 1461582:RZ44_RS09840
uniprot id: A0A078MAW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

1461582:RZ44 RS05635
gene id: 1461582:RZ44_RS05635
uniprot id: A0A078M8G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1461582:RZ44 RS10705
gene id: 1461582:RZ44_RS10705
uniprot id: A0A078M8V3
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1461582:RZ44 RS03690
gene id: 1461582:RZ44_RS03690
uniprot id: A0A078M5L5
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1461582:RZ44 RS02315
gene id: 1461582:RZ44_RS02315
uniprot id: A0A078M406
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

1461582:RZ44 RS03340
gene id: 1461582:RZ44_RS03340
uniprot id: A0A078M594
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1461582:RZ44 RS01605
gene id: 1461582:RZ44_RS01605
uniprot id: A0A078LZ07
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. YjcG family.

1461582:RZ44 RS07630
gene id: 1461582:RZ44_RS07630
uniprot id: A0A078M3F2
names: Similarity
messages: Belongs to the MQO family.

1461582:RZ44 RS09995
gene id: 1461582:RZ44_RS09995
uniprot id: A0A078M7M7
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1461582:RZ44 RS02325
gene id: 1461582:RZ44_RS02325
uniprot id: A0A078LZR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1461582:RZ44 RS06490
gene id: 1461582:RZ44_RS06490
uniprot id: A0A078M7P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1461582:RZ44 RS00090
gene id: 1461582:RZ44_RS00090
uniprot id: A0A078LXZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1461582:RZ44 RS04940
gene id: 1461582:RZ44_RS04940
uniprot id: A0A078M341
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1461582:RZ44 RS02220
gene id: 1461582:RZ44_RS02220
uniprot id: A0A078M3X2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. DivIB subfamily.
messages: Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
messages: Cell membrane

1461582:RZ44 RS06370
gene id: 1461582:RZ44_RS06370
uniprot id: A0A078M9K3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1461582:RZ44 RS05960
gene id: 1461582:RZ44_RS05960
uniprot id: A0A078M744
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1461582:RZ44 RS03425
gene id: 1461582:RZ44_RS03425
uniprot id: A0A078LXH6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1461582:RZ44 RS01235
gene id: 1461582:RZ44_RS01235
uniprot id: A0A078LYS2
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

1461582:RZ44 RS02565
gene id: 1461582:RZ44_RS02565
uniprot id: A0A078M2G9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1461582:RZ44 RS05000
gene id: 1461582:RZ44_RS05000
uniprot id: A0A078M364
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1461582:RZ44 RS03875
gene id: 1461582:RZ44_RS03875
uniprot id: A0A078M5T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1461582:RZ44 RS10425
gene id: 1461582:RZ44_RS10425
uniprot id: A0A078M8I7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1461582:RZ44 RS02580
gene id: 1461582:RZ44_RS02580
uniprot id: A0A078LWH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1461582:RZ44 RS07930
gene id: 1461582:RZ44_RS07930
uniprot id: A0A078M7N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA which binds and tethers DNA polymerases and other proteins to the DNA. The DNA replisome complex has a single clamp-loading complex (3 tau and 1 each of delta, delta', psi and chi subunits) which binds 3 Pol III cores (1 core on the leading strand and 2 on the lagging strand) each with a beta sliding clamp dimer. Additional proteins in the replisome are other copies of gamma, psi and chi, Ssb, DNA helicase and RNA primase.

1461582:RZ44 RS04380
gene id: 1461582:RZ44_RS04380
uniprot id: A0A078LYX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1461582:RZ44 RS05455
gene id: 1461582:RZ44_RS05455
uniprot id: A0A078M8A8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1461582:RZ44 RS05730
gene id: 1461582:RZ44_RS05730
uniprot id: A0A078M0X6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1461582:RZ44 RS06520
gene id: 1461582:RZ44_RS06520
uniprot id: A0A078M212
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1461582:RZ44 RS06230
gene id: 1461582:RZ44_RS06230
uniprot id: A0A078M7B7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

1461582:RZ44 RS09490
gene id: 1461582:RZ44_RS09490
uniprot id: A0A078MEL4
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1461582:RZ44 RS11105
gene id: 1461582:RZ44_RS11105
uniprot id: A0A078LWA4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1461582:RZ44 RS02450
gene id: 1461582:RZ44_RS02450
uniprot id: A0A078LWC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1461582:RZ44 RS01930
gene id: 1461582:RZ44_RS01930
uniprot id: A0A078M1N7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1461582:RZ44 RS08525
gene id: 1461582:RZ44_RS08525
uniprot id: A0A078M8S8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS00445
gene id: 1461582:RZ44_RS00445
uniprot id: A0A078LY82
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1461582:RZ44 RS01595
gene id: 1461582:RZ44_RS01595
uniprot id: A0A078LVJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1461582:RZ44 RS07890
gene id: 1461582:RZ44_RS07890
uniprot id: A0A078MA23
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

1461582:RZ44 RS03405
gene id: 1461582:RZ44_RS03405
uniprot id: A0A078M102
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1461582:RZ44 RS00080
gene id: 1461582:RZ44_RS00080
uniprot id: A0A078LUN6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1461582:RZ44 RS08325
gene id: 1461582:RZ44_RS08325
uniprot id: A0A078M8B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1461582:RZ44 RS07360
gene id: 1461582:RZ44_RS07360
uniprot id: A0A078M916
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1461582:RZ44 RS10020
gene id: 1461582:RZ44_RS10020
uniprot id: A0A078MB56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1461582:RZ44 RS10590
gene id: 1461582:RZ44_RS10590
uniprot id: A0A078MC83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1461582:RZ44 RS00950
gene id: 1461582:RZ44_RS00950
uniprot id: A0A078LV52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1461582:RZ44 RS03845
gene id: 1461582:RZ44_RS03845
uniprot id: A0A078M5S8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1461582:RZ44 RS08820
gene id: 1461582:RZ44_RS08820
uniprot id: A0A078M5S0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1461582:RZ44 RS03880
gene id: 1461582:RZ44_RS03880
uniprot id: A0A078LY71
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1461582:RZ44 RS08180
gene id: 1461582:RZ44_RS08180
uniprot id: A0A078MAF9
names: Function
names: Similarity
messages: Abolishes the inhibitory effect of tetracyclin on protein synthesis by a non-covalent modification of the ribosomes.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1461582:RZ44 RS05055
gene id: 1461582:RZ44_RS05055
uniprot id: A0A078M386
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Monomer.

1461582:RZ44 RS08050
gene id: 1461582:RZ44_RS08050
uniprot id: A0A078M4B6
names: Similarity
messages: Belongs to the UPF0355 family.

1461582:RZ44 RS02195
gene id: 1461582:RZ44_RS02195
uniprot id: A0A078M200
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1461582:RZ44 RS09040
gene id: 1461582:RZ44_RS09040
uniprot id: A0A078M9E1
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS04455
gene id: 1461582:RZ44_RS04455
uniprot id: A0A078M4S2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1461582:RZ44 RS01190
gene id: 1461582:RZ44_RS01190
uniprot id: A0A078M2M3
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1461582:RZ44 RS03695
gene id: 1461582:RZ44_RS03695
uniprot id: A0A078LXV8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1461582:RZ44 RS01650
gene id: 1461582:RZ44_RS01650
uniprot id: A0A078LYU2
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of L-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS09435
gene id: 1461582:RZ44_RS09435
uniprot id: A0A078M6M9
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1461582:RZ44 RS01975
gene id: 1461582:RZ44_RS01975
uniprot id: A0A078M3M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS09640
gene id: 1461582:RZ44_RS09640
uniprot id: A0A078MAA6
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1461582:RZ44 RS05225
gene id: 1461582:RZ44_RS05225
uniprot id: A0A078M3K5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS02420
gene id: 1461582:RZ44_RS02420
uniprot id: A0A078LZQ6
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1461582:RZ44 RS10445
gene id: 1461582:RZ44_RS10445
uniprot id: A0A078M8J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1461582:RZ44 RS00230
gene id: 1461582:RZ44_RS00230
uniprot id: A0A078M0J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1461582:RZ44 RS03930
gene id: 1461582:RZ44_RS03930
uniprot id: A0A078LYA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1461582:RZ44 RS03555
gene id: 1461582:RZ44_RS03555
uniprot id: A0A078M0Z5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1461582:RZ44 RS05150
gene id: 1461582:RZ44_RS05150
uniprot id: A0A078M7Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1461582:RZ44 RS04790
gene id: 1461582:RZ44_RS04790
uniprot id: A0A078LZK6
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1461582:RZ44 RS08870
gene id: 1461582:RZ44_RS08870
uniprot id: A0A078M9A0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1461582:RZ44 RS06785
gene id: 1461582:RZ44_RS06785
uniprot id: A0A078M5J8
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS01195
gene id: 1461582:RZ44_RS01195
uniprot id: A0A078M153
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1461582:RZ44 RS10430
gene id: 1461582:RZ44_RS10430
uniprot id: A0A078MBR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1461582:RZ44 RS09390
gene id: 1461582:RZ44_RS09390
uniprot id: A0A078MCB5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1461582:RZ44 RS08590
gene id: 1461582:RZ44_RS08590
uniprot id: A0A078M5I5
names: Function
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

1461582:RZ44 RS00470
gene id: 1461582:RZ44_RS00470
uniprot id: A0A078LY87
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1461582:RZ44 RS06615
gene id: 1461582:RZ44_RS06615
uniprot id: A0A078M277
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1461582:RZ44 RS01805
gene id: 1461582:RZ44_RS01805
uniprot id: A0A078M3C6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1461582:RZ44 RS02605
gene id: 1461582:RZ44_RS02605
uniprot id: A0A078M4F2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1461582:RZ44 RS01675
gene id: 1461582:RZ44_RS01675
uniprot id: A0A078LYU6
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS04550
gene id: 1461582:RZ44_RS04550
uniprot id: A0A078M2K3
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1461582:RZ44 RS05625
gene id: 1461582:RZ44_RS05625
uniprot id: A0A078M8G1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS03780
gene id: 1461582:RZ44_RS03780
uniprot id: A0A078M5Q2
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS02260
gene id: 1461582:RZ44_RS02260
uniprot id: A0A078LZH7
names: Subcellular Location Annotation
messages: Cytoplasm

1461582:RZ44 RS06285
gene id: 1461582:RZ44_RS06285
uniprot id: A0A078M4Z5
names: Similarity
messages: Belongs to the RNase H family.

1461582:RZ44 RS10635
gene id: 1461582:RZ44_RS10635
uniprot id: A0A078MCA7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1461582:RZ44 RS09480
gene id: 1461582:RZ44_RS09480
uniprot id: A0A078MA13
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1461582:RZ44 RS01105
gene id: 1461582:RZ44_RS01105
uniprot id: A0A078LYJ7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS09160
gene id: 1461582:RZ44_RS09160
uniprot id: A0A078M660
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS09685
gene id: 1461582:RZ44_RS09685
uniprot id: A0A078MAL7
names: Similarity
messages: Belongs to the FBPase class 2 family.

1461582:RZ44 RS06415
gene id: 1461582:RZ44_RS06415
uniprot id: A0A078M7L0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

1461582:RZ44 RS01385
gene id: 1461582:RZ44_RS01385
uniprot id: A0A078LYW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.
messages: Catalyzes the interconversion of ornithine to glutamate semialdehyde.
messages: Cytoplasm

1461582:RZ44 RS10710
gene id: 1461582:RZ44_RS10710
uniprot id: A0A078MGS0
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS08605
gene id: 1461582:RZ44_RS08605
uniprot id: A0A078MB88
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS00065
gene id: 1461582:RZ44_RS00065
uniprot id: A0A078LXZ4
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1461582:RZ44 RS02520
gene id: 1461582:RZ44_RS02520
uniprot id: A0A078LZX3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1461582:RZ44 RS07955
gene id: 1461582:RZ44_RS07955
uniprot id: A0A078M7P9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS04425
gene id: 1461582:RZ44_RS04425
uniprot id: A0A078M6P0
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

1461582:RZ44 RS06825
gene id: 1461582:RZ44_RS06825
uniprot id: A0A078M2K1
names: Similarity
messages: Belongs to the DSD1 family.

1461582:RZ44 RS01615
gene id: 1461582:RZ44_RS01615
uniprot id: A0A078M1F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1461582:RZ44 RS04400
gene id: 1461582:RZ44_RS04400
uniprot id: A0A078M222
names: Subcellular Location Annotation
messages: Cytoplasm

1461582:RZ44 RS08665
gene id: 1461582:RZ44_RS08665
uniprot id: A0A078MBB9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1461582:RZ44 RS04075
gene id: 1461582:RZ44_RS04075
uniprot id: A0A078M4D3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1461582:RZ44 RS07385
gene id: 1461582:RZ44_RS07385
uniprot id: A0A078M930
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Glutamine synthetase (GS) is an unusual multitasking protein that functions as an enzyme, a transcription coregulator, and a chaperone in ammonium assimilation and in the regulation of genes involved in nitrogen metabolism. It catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia. Feedback-inhibited GlnA also interacts with and regulates the activity of the transcriptional regulator TnrA. During nitrogen limitation, TnrA is in its DNA-binding active state and turns on the transcription of genes required for nitrogen assimilation. Under conditions of nitrogen excess, feedback-inhibited GlnA forms a stable complex with TnrA, which inhibits its DNA-binding activity. In contrast, feedback-inhibited GlnA acts as a chaperone to stabilize the DNA-binding activity of GlnR, which represses the transcription of nitrogen assimilation genes.
messages: Oligomer of 12 subunits arranged in the form of two hexagons. In its feedback-inhibited form, interacts with TnrA in order to block its DNA-binding activity.

1461582:RZ44 RS05505
gene id: 1461582:RZ44_RS05505
uniprot id: A0A078M3U8
names: Cofactor
messages: Binds 1 FAD per subunit.

1461582:RZ44 RS04030
gene id: 1461582:RZ44_RS04030
uniprot id: A0A078M1V8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

1461582:RZ44 RS07960
gene id: 1461582:RZ44_RS07960
uniprot id: A0A078M460
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1461582:RZ44 RS00770
gene id: 1461582:RZ44_RS00770
uniprot id: A0A078M2F6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS05640
gene id: 1461582:RZ44_RS05640
uniprot id: A0A078M6G3
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
messages: Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).

1461582:RZ44 RS01270
gene id: 1461582:RZ44_RS01270
uniprot id: A0A078M1A1
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1461582:RZ44 RS04890
gene id: 1461582:RZ44_RS04890
uniprot id: A0A078M304
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1461582:RZ44 RS05095
gene id: 1461582:RZ44_RS05095
uniprot id: A0A078M3B9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1461582:RZ44 RS09700
gene id: 1461582:RZ44_RS09700
uniprot id: A0A078MEY1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1461582:RZ44 RS03095
gene id: 1461582:RZ44_RS03095
uniprot id: A0A078M3F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS09445
gene id: 1461582:RZ44_RS09445
uniprot id: A0A078M6N9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1461582:RZ44 RS01485
gene id: 1461582:RZ44_RS01485
uniprot id: A0A078M353
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1461582:RZ44 RS02440
gene id: 1461582:RZ44_RS02440
uniprot id: A0A078LZU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1461582:RZ44 RS10140
gene id: 1461582:RZ44_RS10140
uniprot id: A0A078MDJ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1461582:RZ44 RS08950
gene id: 1461582:RZ44_RS08950
uniprot id: A0A078M9F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1461582:RZ44 RS02280
gene id: 1461582:RZ44_RS02280
uniprot id: A0A078M237
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

1461582:RZ44 RS00920
gene id: 1461582:RZ44_RS00920
uniprot id: A0A078M2H8
names: PTM
messages: Binds 1 heme c group covalently per subunit.

1461582:RZ44 RS09330
gene id: 1461582:RZ44_RS09330
uniprot id: A0A078ME42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.
messages: Homotetramer.

1461582:RZ44 RS01250
gene id: 1461582:RZ44_RS01250
uniprot id: A0A078LVC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1461582:RZ44 RS02455
gene id: 1461582:RZ44_RS02455
uniprot id: A0A078LZV1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1461582:RZ44 RS04720
gene id: 1461582:RZ44_RS04720
uniprot id: A0A078LZF3
names: Similarity
messages: Belongs to the PemK/MazF family.

1461582:RZ44 RS08340
gene id: 1461582:RZ44_RS08340
uniprot id: A0A078M4W9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1461582:RZ44 RS04460
gene id: 1461582:RZ44_RS04460
uniprot id: A0A078M2E2
names: Subcellular Location Annotation
messages: Cell membrane

1461582:RZ44 RS04295
gene id: 1461582:RZ44_RS04295
uniprot id: A0A078M1X7
names: Similarity
messages: Belongs to the UPF0403 family.

1461582:RZ44 RS05655
gene id: 1461582:RZ44_RS05655
uniprot id: A0A078M0T6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1461582:RZ44 RS09990
gene id: 1461582:RZ44_RS09990
uniprot id: A0A078MAX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1461582:RZ44 RS02085
gene id: 1461582:RZ44_RS02085
uniprot id: A0A078LZA0
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS03225
gene id: 1461582:RZ44_RS03225
uniprot id: A0A078M0U6
names: Function
names: Similarity
messages: Belongs to the nitronate monooxygenase family. NMO class I subfamily.
messages: Nitronate monooxygenase that uses molecular oxygen to catalyze the oxidative denitrification of alkyl nitronates. Acts on propionate 3-nitronate (P3N), the presumed physiological substrate. Probably functions in the detoxification of P3N, a metabolic poison produced by plants and fungi as a defense mechanism.

1461582:RZ44 RS01990
gene id: 1461582:RZ44_RS01990
uniprot id: A0A078M1R1
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS01345
gene id: 1461582:RZ44_RS01345
uniprot id: A0A078M1B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS07065
gene id: 1461582:RZ44_RS07065
uniprot id: A0A078M8N2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS10905
gene id: 1461582:RZ44_RS10905
uniprot id: A0A078MCI9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1461582:RZ44 RS00995
gene id: 1461582:RZ44_RS00995
uniprot id: A0A078M118
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1461582:RZ44 RS03595
gene id: 1461582:RZ44_RS03595
uniprot id: A0A078M5H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1461582:RZ44 RS03210
gene id: 1461582:RZ44_RS03210
uniprot id: A0A078M0L2
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1461582:RZ44 RS06015
gene id: 1461582:RZ44_RS06015
uniprot id: A0A078M4H4
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS03925
gene id: 1461582:RZ44_RS03925
uniprot id: A0A078M5W0
names: Similarity
messages: Belongs to the TlyA family.

1461582:RZ44 RS06745
gene id: 1461582:RZ44_RS06745
uniprot id: A0A078M2F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

1461582:RZ44 RS02775
gene id: 1461582:RZ44_RS02775
uniprot id: A0A078M4Q3
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1461582:RZ44 RS03350
gene id: 1461582:RZ44_RS03350
uniprot id: A0A078M598
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1461582:RZ44 RS02975
gene id: 1461582:RZ44_RS02975
uniprot id: A0A078LX15
names: Similarity
messages: Belongs to the CdaR family.

1461582:RZ44 RS08905
gene id: 1461582:RZ44_RS08905
uniprot id: A0A078MBM6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1461582:RZ44 RS07745
gene id: 1461582:RZ44_RS07745
uniprot id: A0A078M3R6
names: Similarity
messages: Belongs to the universal stress protein A family.

1461582:RZ44 RS02350
gene id: 1461582:RZ44_RS02350
uniprot id: A0A078LZR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1461582:RZ44 RS07240
gene id: 1461582:RZ44_RS07240
uniprot id: A0A078M6F5
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

1461582:RZ44 RS01090
gene id: 1461582:RZ44_RS01090
uniprot id: A0A078M2K0
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1461582:RZ44 RS06630
gene id: 1461582:RZ44_RS06630
uniprot id: A0A078M9X5
names: Similarity
messages: Belongs to the glutamine synthetase family.

1461582:RZ44 RS06330
gene id: 1461582:RZ44_RS06330
uniprot id: A0A078M1Q1
names: Similarity
messages: Belongs to the CdaR family.

1461582:RZ44 RS06005
gene id: 1461582:RZ44_RS06005
uniprot id: A0A078M1E8
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1461582:RZ44 RS09930
gene id: 1461582:RZ44_RS09930
uniprot id: A0A078MB26
names: Similarity
messages: Belongs to the catalase family.

1461582:RZ44 RS00985
gene id: 1461582:RZ44_RS00985
uniprot id: A0A078LYJ5
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1461582:RZ44 RS01325
gene id: 1461582:RZ44_RS01325
uniprot id: A0A078LVF3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1461582:RZ44 RS01860
gene id: 1461582:RZ44_RS01860
uniprot id: A0A078LZ84
names: Similarity
messages: Belongs to the GARS family.

1461582:RZ44 RS03980
gene id: 1461582:RZ44_RS03980
uniprot id: A0A078LYD0
names: Similarity
messages: Belongs to the UPF0403 family.

1461582:RZ44 RS06820
gene id: 1461582:RZ44_RS06820
uniprot id: A0A078M888
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS01770
gene id: 1461582:RZ44_RS01770
uniprot id: A0A078LYW5
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1461582:RZ44 RS08720
gene id: 1461582:RZ44_RS08720
uniprot id: A0A078M5N0
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS06030
gene id: 1461582:RZ44_RS06030
uniprot id: A0A078M963
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS04155
gene id: 1461582:RZ44_RS04155
uniprot id: A0A078M208
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1461582:RZ44 RS10305
gene id: 1461582:RZ44_RS10305
uniprot id: A0A078M8C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS06650
gene id: 1461582:RZ44_RS06650
uniprot id: A0A078M9Y3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1461582:RZ44 RS11060
gene id: 1461582:RZ44_RS11060
uniprot id: A0A078M8I2
names: Similarity
messages: Belongs to the UPF0355 family.

1461582:RZ44 RS06610
gene id: 1461582:RZ44_RS06610
uniprot id: A0A078M9W8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1461582:RZ44 RS02535
gene id: 1461582:RZ44_RS02535
uniprot id: A0A078LZX7
names: Similarity
messages: Belongs to the DprA/Smf family.

1461582:RZ44 RS01020
gene id: 1461582:RZ44_RS01020
uniprot id: A0A078M122
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1461582:RZ44 RS04430
gene id: 1461582:RZ44_RS04430
uniprot id: A0A078M6P4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1461582:RZ44 RS02320
gene id: 1461582:RZ44_RS02320
uniprot id: A0A078LW71
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

1461582:RZ44 RS03665
gene id: 1461582:RZ44_RS03665
uniprot id: A0A078M5K6
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1461582:RZ44 RS05290
gene id: 1461582:RZ44_RS05290
uniprot id: A0A078M856
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1461582:RZ44 RS06565
gene id: 1461582:RZ44_RS06565
uniprot id: A0A078M9U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1461582:RZ44 RS02165
gene id: 1461582:RZ44_RS02165
uniprot id: A0A078LZL6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS02600
gene id: 1461582:RZ44_RS02600
uniprot id: A0A078M006
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1461582:RZ44 RS09865
gene id: 1461582:RZ44_RS09865
uniprot id: A0A078M7G0
names: Similarity
messages: Belongs to the DEAD box helicase family.

1461582:RZ44 RS02230
gene id: 1461582:RZ44_RS02230
uniprot id: A0A078M220
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1461582:RZ44 RS03450
gene id: 1461582:RZ44_RS03450
uniprot id: A0A078M0U5
names: Similarity
messages: Belongs to the UPF0297 family.

1461582:RZ44 RS10695
gene id: 1461582:RZ44_RS10695
uniprot id: A0A078M8U8
names: Similarity
messages: Belongs to the AB hydrolase superfamily.

1461582:RZ44 RS11335
gene id: 1461582:RZ44_RS11335
uniprot id: A0A078M9Q1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1461582:RZ44 RS05570
gene id: 1461582:RZ44_RS05570
uniprot id: A0A078M0Q2
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS08890
gene id: 1461582:RZ44_RS08890
uniprot id: A0A078M9A6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1461582:RZ44 RS08560
gene id: 1461582:RZ44_RS08560
uniprot id: A0A078M5H5
names: Similarity
names: Subunit
messages: Belongs to the azoreductase type 2 family.
messages: Homotetramer.

1461582:RZ44 RS01495
gene id: 1461582:RZ44_RS01495
uniprot id: A0A078LVH5
names: Activity Regulation
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), including enzyme I, and histidine-containing protein (HPr) are required for the phosphorylation, which leads to the activation of the enzyme.

1461582:RZ44 RS03635
gene id: 1461582:RZ44_RS03635
uniprot id: A0A078M3W3
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1461582:RZ44 RS10855
gene id: 1461582:RZ44_RS10855
uniprot id: A0A078MEU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1461582:RZ44 RS00615
gene id: 1461582:RZ44_RS00615
uniprot id: A0A078LYD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1461582:RZ44 RS07025
gene id: 1461582:RZ44_RS07025
uniprot id: A0A078M659
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1461582:RZ44 RS06505
gene id: 1461582:RZ44_RS06505
uniprot id: A0A078M9S2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1461582:RZ44 RS10560
gene id: 1461582:RZ44_RS10560
uniprot id: A0A078MGK5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS02290
gene id: 1461582:RZ44_RS02290
uniprot id: A0A078M3Z7
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1461582:RZ44 RS10825
gene id: 1461582:RZ44_RS10825
uniprot id: A0A078MCL1
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1461582:RZ44 RS02615
gene id: 1461582:RZ44_RS02615
uniprot id: A0A078M013
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1461582:RZ44 RS06685
gene id: 1461582:RZ44_RS06685
uniprot id: A0A078M5K7
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.

1461582:RZ44 RS08360
gene id: 1461582:RZ44_RS08360
uniprot id: A0A078MAT5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
messages: The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.

1461582:RZ44 RS05255
gene id: 1461582:RZ44_RS05255
uniprot id: A0A078M622
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1461582:RZ44 RS05240
gene id: 1461582:RZ44_RS05240
uniprot id: A0A078M841
names: Subcellular Location Annotation
messages: Cytoplasm

1461582:RZ44 RS07255
gene id: 1461582:RZ44_RS07255
uniprot id: A0A078M6F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family. Thioredoxin-coupled ArsC subfamily.
messages: Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)].
messages: Cytoplasm

1461582:RZ44 RS07250
gene id: 1461582:RZ44_RS07250
uniprot id: A0A078MB03
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1461582:RZ44 RS09585
gene id: 1461582:RZ44_RS09585
uniprot id: A0A078MA84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1461582:RZ44 RS05920
gene id: 1461582:RZ44_RS05920
uniprot id: A0A078M8V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1461582:RZ44 RS09670
gene id: 1461582:RZ44_RS09670
uniprot id: A0A078M748
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS00820
gene id: 1461582:RZ44_RS00820
uniprot id: A0A078M2G2
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Tetramer of two alpha and two beta subunits.

1461582:RZ44 RS03715
gene id: 1461582:RZ44_RS03715
uniprot id: A0A078M3Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS05470
gene id: 1461582:RZ44_RS05470
uniprot id: A0A078M8B1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS09095
gene id: 1461582:RZ44_RS09095
uniprot id: A0A078MBT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for heme-iron. Responsible for the translocation of the substrate across the membrane.

1461582:RZ44 RS08765
gene id: 1461582:RZ44_RS08765
uniprot id: A0A078M952
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1461582:RZ44 RS03550
gene id: 1461582:RZ44_RS03550
uniprot id: A0A078M3S7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1461582:RZ44 RS03325
gene id: 1461582:RZ44_RS03325
uniprot id: A0A078M0Y2
names: Similarity
messages: Belongs to the RecJ family.

1461582:RZ44 RS06535
gene id: 1461582:RZ44_RS06535
uniprot id: A0A078M5C9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1461582:RZ44 RS05375
gene id: 1461582:RZ44_RS05375
uniprot id: A0A078M882
names: Function
names: Similarity
messages: Belongs to the histone deacetylase family.
messages: Role in growth on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source.

1461582:RZ44 RS02475
gene id: 1461582:RZ44_RS02475
uniprot id: A0A078LWD3
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

1461582:RZ44 RS06930
gene id: 1461582:RZ44_RS06930
uniprot id: A0A078MAK4
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS03290
gene id: 1461582:RZ44_RS03290
uniprot id: A0A078M0X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1461582:RZ44 RS07970
gene id: 1461582:RZ44_RS07970
uniprot id: A0A078MA50
names: Similarity
messages: Belongs to the ParB family.

1461582:RZ44 RS08265
gene id: 1461582:RZ44_RS08265
uniprot id: A0A078M868
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS09740
gene id: 1461582:RZ44_RS09740
uniprot id: A0A078MAH0
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1461582:RZ44 RS08730
gene id: 1461582:RZ44_RS08730
uniprot id: A0A078MBE7
names: Function
names: Similarity
messages: Belongs to the CtsR family.
messages: Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region.

1461582:RZ44 RS08275
gene id: 1461582:RZ44_RS08275
uniprot id: A0A078M872
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1461582:RZ44 RS05800
gene id: 1461582:RZ44_RS05800
uniprot id: A0A078M119
names: Subcellular Location Annotation
messages: Cytoplasm

1461582:RZ44 RS05720
gene id: 1461582:RZ44_RS05720
uniprot id: A0A078M0W9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1461582:RZ44 RS06720
gene id: 1461582:RZ44_RS06720
uniprot id: A0A078M5F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS02595
gene id: 1461582:RZ44_RS02595
uniprot id: A0A078LWI2
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

1461582:RZ44 RS09055
gene id: 1461582:RZ44_RS09055
uniprot id: A0A078MDU6
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1461582:RZ44 RS08855
gene id: 1461582:RZ44_RS08855
uniprot id: A0A078M9A4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1461582:RZ44 RS09890
gene id: 1461582:RZ44_RS09890
uniprot id: A0A078MAS0
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1461582:RZ44 RS04300
gene id: 1461582:RZ44_RS04300
uniprot id: A0A078M6J6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS01660
gene id: 1461582:RZ44_RS01660
uniprot id: A0A078M384
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1461582:RZ44 RS00055
gene id: 1461582:RZ44_RS00055
uniprot id: A0A078LUM0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1461582:RZ44 RS10215
gene id: 1461582:RZ44_RS10215
uniprot id: A0A078MFT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS08385
gene id: 1461582:RZ44_RS08385
uniprot id: A0A078M8E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

1461582:RZ44 RS01970
gene id: 1461582:RZ44_RS01970
uniprot id: A0A078LZ45
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS01390
gene id: 1461582:RZ44_RS01390
uniprot id: A0A078M335
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1461582:RZ44 RS03790
gene id: 1461582:RZ44_RS03790
uniprot id: A0A078M1E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1461582:RZ44 RS01515
gene id: 1461582:RZ44_RS01515
uniprot id: A0A078M1E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS01545
gene id: 1461582:RZ44_RS01545
uniprot id: A0A078LVI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArsC family. Spx subfamily.
messages: Cytoplasm
messages: Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes. Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP). This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.
messages: Interacts with the C-terminal domain of the alpha subunit of the RNAP.

1461582:RZ44 RS06965
gene id: 1461582:RZ44_RS06965
uniprot id: A0A078M8I1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1461582:RZ44 RS04985
gene id: 1461582:RZ44_RS04985
uniprot id: A0A078M354
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS10755
gene id: 1461582:RZ44_RS10755
uniprot id: A0A078M8Y6
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS01075
gene id: 1461582:RZ44_RS01075
uniprot id: A0A078LV76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1461582:RZ44 RS08595
gene id: 1461582:RZ44_RS08595
uniprot id: A0A078MD83
names: Similarity
messages: Belongs to the RutC family.

1461582:RZ44 RS01850
gene id: 1461582:RZ44_RS01850
uniprot id: A0A078M3E3
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS06530
gene id: 1461582:RZ44_RS06530
uniprot id: A0A078M9T4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1461582:RZ44 RS00980
gene id: 1461582:RZ44_RS00980
uniprot id: A0A078LYH7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1461582:RZ44 RS08915
gene id: 1461582:RZ44_RS08915
uniprot id: A0A078MDR5
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

1461582:RZ44 RS10890
gene id: 1461582:RZ44_RS10890
uniprot id: A0A078MEW7
names: Function
messages: May be involved in multidrug export. Transmembrane domains (TMD) form a pore in the cell membrane and the ATP-binding domain (NBD) is responsible for energy generation.

1461582:RZ44 RS04695
gene id: 1461582:RZ44_RS04695
uniprot id: A0A078M2N2
names: Similarity
messages: Belongs to the CpsD/CapB family.

1461582:RZ44 RS01955
gene id: 1461582:RZ44_RS01955
uniprot id: A0A078LVT7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes.
messages: The active site is a redox-active disulfide bond.

1461582:RZ44 RS00340
gene id: 1461582:RZ44_RS00340
uniprot id: A0A078LY93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS08000
gene id: 1461582:RZ44_RS08000
uniprot id: A0A078MA68
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1461582:RZ44 RS01415
gene id: 1461582:RZ44_RS01415
uniprot id: A0A078M340
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1461582:RZ44 RS01225
gene id: 1461582:RZ44_RS01225
uniprot id: A0A078LVA5
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

1461582:RZ44 RS02765
gene id: 1461582:RZ44_RS02765
uniprot id: A0A078M067
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1461582:RZ44 RS01045
gene id: 1461582:RZ44_RS01045
uniprot id: A0A078M125
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1461582:RZ44 RS00520
gene id: 1461582:RZ44_RS00520
uniprot id: A0A078LY96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1461582:RZ44 RS00815
gene id: 1461582:RZ44_RS00815
uniprot id: A0A078LYG5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1461582:RZ44 RS02225
gene id: 1461582:RZ44_RS02225
uniprot id: A0A078LW27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1461582:RZ44 RS08825
gene id: 1461582:RZ44_RS08825
uniprot id: A0A078MDM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1461582:RZ44 RS03675
gene id: 1461582:RZ44_RS03675
uniprot id: A0A078M1A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1461582:RZ44 RS08770
gene id: 1461582:RZ44_RS08770
uniprot id: A0A078MBH0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS03590
gene id: 1461582:RZ44_RS03590
uniprot id: A0A078M115
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1461582:RZ44 RS04920
gene id: 1461582:RZ44_RS04920
uniprot id: A0A078LZW1
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1461582:RZ44 RS09735
gene id: 1461582:RZ44_RS09735
uniprot id: A0A078MCZ8
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

1461582:RZ44 RS02780
gene id: 1461582:RZ44_RS02780
uniprot id: A0A078M342
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1461582:RZ44 RS07635
gene id: 1461582:RZ44_RS07635
uniprot id: A0A078MBM8
names: Similarity
messages: Belongs to the universal stress protein A family.

1461582:RZ44 RS09780
gene id: 1461582:RZ44_RS09780
uniprot id: A0A078MD19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1461582:RZ44 RS09405
gene id: 1461582:RZ44_RS09405
uniprot id: A0A078MCC8
names: Similarity
messages: Belongs to the YciI family.

1461582:RZ44 RS10625
gene id: 1461582:RZ44_RS10625
uniprot id: A0A078MCA1
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1461582:RZ44 RS00210
gene id: 1461582:RZ44_RS00210
uniprot id: A0A078LUR1
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1461582:RZ44 RS01095
gene id: 1461582:RZ44_RS01095
uniprot id: A0A078M135
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1461582:RZ44 RS00500
gene id: 1461582:RZ44_RS00500
uniprot id: A0A078M2B5
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

1461582:RZ44 RS09460
gene id: 1461582:RZ44_RS09460
uniprot id: A0A078M6Q2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1461582:RZ44 RS05905
gene id: 1461582:RZ44_RS05905
uniprot id: A0A078M184
names: Similarity
messages: Belongs to the UPF0342 family.

1461582:RZ44 RS06420
gene id: 1461582:RZ44_RS06420
uniprot id: A0A078M4V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS05200
gene id: 1461582:RZ44_RS05200
uniprot id: A0A078M3I8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1461582:RZ44 RS04895
gene id: 1461582:RZ44_RS04895
uniprot id: A0A078LZT1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1461582:RZ44 RS02655
gene id: 1461582:RZ44_RS02655
uniprot id: A0A078M2M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1461582:RZ44 RS09695
gene id: 1461582:RZ44_RS09695
uniprot id: A0A078M755
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1461582:RZ44 RS00200
gene id: 1461582:RZ44_RS00200
uniprot id: A0A078M266
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

1461582:RZ44 RS09980
gene id: 1461582:RZ44_RS09980
uniprot id: A0A078MFF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1461582:RZ44 RS03785
gene id: 1461582:RZ44_RS03785
uniprot id: A0A078LY20
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS01085
gene id: 1461582:RZ44_RS01085
uniprot id: A0A078LYM2
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS01410
gene id: 1461582:RZ44_RS01410
uniprot id: A0A078LYW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1461582:RZ44 RS07050
gene id: 1461582:RZ44_RS07050
uniprot id: A0A078M2U3
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS10245
gene id: 1461582:RZ44_RS10245
uniprot id: A0A078MBJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1461582:RZ44 RS00325
gene id: 1461582:RZ44_RS00325
uniprot id: A0A078M288
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS09965
gene id: 1461582:RZ44_RS09965
uniprot id: A0A078M7L2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1461582:RZ44 RS02495
gene id: 1461582:RZ44_RS02495
uniprot id: A0A078M4A0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1461582:RZ44 RS07145
gene id: 1461582:RZ44_RS07145
uniprot id: A0A078M6B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1461582:RZ44 RS02215
gene id: 1461582:RZ44_RS02215
uniprot id: A0A078LZF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1461582:RZ44 RS09830
gene id: 1461582:RZ44_RS09830
uniprot id: A0A078M7D6
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1461582:RZ44 RS08835
gene id: 1461582:RZ44_RS08835
uniprot id: A0A078M981
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1461582:RZ44 RS02030
gene id: 1461582:RZ44_RS02030
uniprot id: A0A078LVW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1461582:RZ44 RS03935
gene id: 1461582:RZ44_RS03935
uniprot id: A0A078M1L3
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1461582:RZ44 RS01695
gene id: 1461582:RZ44_RS01695
uniprot id: A0A078LVL1
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival.

1461582:RZ44 RS03285
gene id: 1461582:RZ44_RS03285
uniprot id: A0A078LXB9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1461582:RZ44 RS09525
gene id: 1461582:RZ44_RS09525
uniprot id: A0A078MEP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1461582:RZ44 RS10470
gene id: 1461582:RZ44_RS10470
uniprot id: A0A078M8K5
names: Similarity
messages: Belongs to the peptidase C15 family.

1461582:RZ44 RS05380
gene id: 1461582:RZ44_RS05380
uniprot id: A0A078M0H2
names: Function
messages: Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.

1461582:RZ44 RS03905
gene id: 1461582:RZ44_RS03905
uniprot id: A0A078M5V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1461582:RZ44 RS01230
gene id: 1461582:RZ44_RS01230
uniprot id: A0A078LYN3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

1461582:RZ44 RS10225
gene id: 1461582:RZ44_RS10225
uniprot id: A0A078MDP9
names: Similarity
messages: Belongs to the AB hydrolase superfamily.

1461582:RZ44 RS00330
gene id: 1461582:RZ44_RS00330
uniprot id: A0A078M0L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS06945
gene id: 1461582:RZ44_RS06945
uniprot id: A0A078M624
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1461582:RZ44 RS10830
gene id: 1461582:RZ44_RS10830
uniprot id: A0A078MES4
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS02330
gene id: 1461582:RZ44_RS02330
uniprot id: A0A078M262
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1461582:RZ44 RS03565
gene id: 1461582:RZ44_RS03565
uniprot id: A0A078LXN1
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1461582:RZ44 RS07350
gene id: 1461582:RZ44_RS07350
uniprot id: A0A078M910
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1461582:RZ44 RS11000
gene id: 1461582:RZ44_RS11000
uniprot id: A0A078M7T3
names: Similarity
messages: Belongs to the TRAP family.

1461582:RZ44 RS00165
gene id: 1461582:RZ44_RS00165
uniprot id: A0A078LY14
names: Similarity
messages: Belongs to the ClpA/ClpB family. ClpC subfamily.

1461582:RZ44 RS02945
gene id: 1461582:RZ44_RS02945
uniprot id: A0A078M0J3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1461582:RZ44 RS03160
gene id: 1461582:RZ44_RS03160
uniprot id: A0A078M0S4
names: Similarity
names: Subunit
messages: Belongs to the SMC family. SbcC subfamily.
messages: Heterodimer of SbcC and SbcD.

1461582:RZ44 RS01480
gene id: 1461582:RZ44_RS01480
uniprot id: A0A078LYY2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS09845
gene id: 1461582:RZ44_RS09845
uniprot id: A0A078M7E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS08830
gene id: 1461582:RZ44_RS08830
uniprot id: A0A078M5S7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1461582:RZ44 RS01005
gene id: 1461582:RZ44_RS01005
uniprot id: A0A078LYK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1461582:RZ44 RS03895
gene id: 1461582:RZ44_RS03895
uniprot id: A0A078M1D4
names: Function
names: Similarity
messages: Belongs to the asp23 family.
messages: May play a key role in alkaline pH tolerance.

1461582:RZ44 RS06950
gene id: 1461582:RZ44_RS06950
uniprot id: A0A078M8H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1461582:RZ44 RS03330
gene id: 1461582:RZ44_RS03330
uniprot id: A0A078M3K3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

1461582:RZ44 RS04685
gene id: 1461582:RZ44_RS04685
uniprot id: A0A078M2M9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1461582:RZ44 RS10145
gene id: 1461582:RZ44_RS10145
uniprot id: A0A078MB57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1461582:RZ44 RS09085
gene id: 1461582:RZ44_RS09085
uniprot id: A0A078M628
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1461582:RZ44 RS04010
gene id: 1461582:RZ44_RS04010
uniprot id: A0A078M4A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Fur family.
messages: Cytoplasm

1461582:RZ44 RS05145
gene id: 1461582:RZ44_RS05145
uniprot id: A0A078M3F5
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer.

1461582:RZ44 RS02790
gene id: 1461582:RZ44_RS02790
uniprot id: A0A078M4R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS07445
gene id: 1461582:RZ44_RS07445
uniprot id: A0A078M6T2
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS06405
gene id: 1461582:RZ44_RS06405
uniprot id: A0A078M9M6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS08235
gene id: 1461582:RZ44_RS08235
uniprot id: A0A078MAJ6
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1461582:RZ44 RS08125
gene id: 1461582:RZ44_RS08125
uniprot id: A0A078MAE4
names: Function
messages: May be involved in multidrug export. Transmembrane domains (TMD) form a pore in the cell membrane and the ATP-binding domain (NBD) is responsible for energy generation.

1461582:RZ44 RS04650
gene id: 1461582:RZ44_RS04650
uniprot id: A0A078M2Q3
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1461582:RZ44 RS10230
gene id: 1461582:RZ44_RS10230
uniprot id: A0A078MBA8
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1461582:RZ44 RS01940
gene id: 1461582:RZ44_RS01940
uniprot id: A0A078M1P2
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1461582:RZ44 RS01295
gene id: 1461582:RZ44_RS01295
uniprot id: A0A078M1A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1461582:RZ44 RS07795
gene id: 1461582:RZ44_RS07795
uniprot id: A0A078M3V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1461582:RZ44 RS01790
gene id: 1461582:RZ44_RS01790
uniprot id: A0A078LYX1
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1461582:RZ44 RS05325
gene id: 1461582:RZ44_RS05325
uniprot id: A0A078M3N7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS06400
gene id: 1461582:RZ44_RS06400
uniprot id: A0A078M561
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1461582:RZ44 RS04215
gene id: 1461582:RZ44_RS04215
uniprot id: A0A078M6F6
names: Function
names: Similarity
messages: 3'-5' exonuclease.
messages: Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.

1461582:RZ44 RS05045
gene id: 1461582:RZ44_RS05045
uniprot id: A0A078M385
names: Function
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.

1461582:RZ44 RS06740
gene id: 1461582:RZ44_RS06740
uniprot id: A0A078MA52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1461582:RZ44 RS05645
gene id: 1461582:RZ44_RS05645
uniprot id: A0A078M3Z4
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS00265
gene id: 1461582:RZ44_RS00265
uniprot id: A0A078LY83
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1461582:RZ44 RS05030
gene id: 1461582:RZ44_RS05030
uniprot id: A0A078M5T0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1461582:RZ44 RS01505
gene id: 1461582:RZ44_RS01505
uniprot id: A0A078LYY8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1461582:RZ44 RS02540
gene id: 1461582:RZ44_RS02540
uniprot id: A0A078M4B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1461582:RZ44 RS06425
gene id: 1461582:RZ44_RS06425
uniprot id: A0A078M1V3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1461582:RZ44 RS05420
gene id: 1461582:RZ44_RS05420
uniprot id: A0A078M3S3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1461582:RZ44 RS01205
gene id: 1461582:RZ44_RS01205
uniprot id: A0A078LYL8
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1461582:RZ44 RS09950
gene id: 1461582:RZ44_RS09950
uniprot id: A0A078MB30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1461582:RZ44 RS08610
gene id: 1461582:RZ44_RS08610
uniprot id: A0A078M8W6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

1461582:RZ44 RS02505
gene id: 1461582:RZ44_RS02505
uniprot id: A0A078LZW9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1461582:RZ44 RS07185
gene id: 1461582:RZ44_RS07185
uniprot id: A0A078MAW7
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS02665
gene id: 1461582:RZ44_RS02665
uniprot id: A0A078M4I5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1461582:RZ44 RS07535
gene id: 1461582:RZ44_RS07535
uniprot id: A0A078M6W3
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1461582:RZ44 RS01015
gene id: 1461582:RZ44_RS01015
uniprot id: A0A078M2I7
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1461582:RZ44 RS09775
gene id: 1461582:RZ44_RS09775
uniprot id: A0A078MAT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1461582:RZ44 RS09110
gene id: 1461582:RZ44_RS09110
uniprot id: A0A078M638
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

1461582:RZ44 RS02105
gene id: 1461582:RZ44_RS02105
uniprot id: A0A078M1V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1461582:RZ44 RS08335
gene id: 1461582:RZ44_RS08335
uniprot id: A0A078MCQ9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1461582:RZ44 RS00095
gene id: 1461582:RZ44_RS00095
uniprot id: A0A078M250
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1461582:RZ44 RS04900
gene id: 1461582:RZ44_RS04900
uniprot id: A0A078M7H7
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1461582:RZ44 RS08785
gene id: 1461582:RZ44_RS08785
uniprot id: A0A078MBH7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1461582:RZ44 RS07345
gene id: 1461582:RZ44_RS07345
uniprot id: A0A078M6L1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1461582:RZ44 RS01425
gene id: 1461582:RZ44_RS01425
uniprot id: A0A078LVG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Essential for cell viability.
messages: Membrane

1461582:RZ44 RS02340
gene id: 1461582:RZ44_RS02340
uniprot id: A0A078M424
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1461582:RZ44 RS10580
gene id: 1461582:RZ44_RS10580
uniprot id: A0A078M8Q3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPase class C family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm

1461582:RZ44 RS01275
gene id: 1461582:RZ44_RS01275
uniprot id: A0A078LVE7
names: Subcellular Location Annotation
messages: Membrane

1461582:RZ44 RS01535
gene id: 1461582:RZ44_RS01535
uniprot id: A0A078M361
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1461582:RZ44 RS02575
gene id: 1461582:RZ44_RS02575
uniprot id: A0A078M4C9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1461582:RZ44 RS07665
gene id: 1461582:RZ44_RS07665
uniprot id: A0A078M9N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1461582:RZ44 RS05345
gene id: 1461582:RZ44_RS05345
uniprot id: A0A078M652
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1461582:RZ44 RS02490
gene id: 1461582:RZ44_RS02490
uniprot id: A0A078LZT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1461582:RZ44 RS07990
gene id: 1461582:RZ44_RS07990
uniprot id: A0A078MC71
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1461582:RZ44 RS09060
gene id: 1461582:RZ44_RS09060
uniprot id: A0A078M619
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the octanoyltransferase LipL family.
messages: Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes.
messages: The reaction proceeds via a thioester-linked acyl-enzyme intermediate.

1461582:RZ44 RS06700
gene id: 1461582:RZ44_RS06700
uniprot id: A0A078M5L6
names: Similarity
messages: Belongs to the MQO family.

1461582:RZ44 RS03600
gene id: 1461582:RZ44_RS03600
uniprot id: A0A078LXP7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1461582:RZ44 RS10440
gene id: 1461582:RZ44_RS10440
uniprot id: A0A078MBR4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

1461582:RZ44 RS02345
gene id: 1461582:RZ44_RS02345
uniprot id: A0A078LW83
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1461582:RZ44 RS07460
gene id: 1461582:RZ44_RS07460
uniprot id: A0A078M6S6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1461582:RZ44 RS01890
gene id: 1461582:RZ44_RS01890
uniprot id: A0A078M1M5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS10015
gene id: 1461582:RZ44_RS10015
uniprot id: A0A078MFH2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1461582:RZ44 RS03585
gene id: 1461582:RZ44_RS03585
uniprot id: A0A078M3U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1461582:RZ44 RS06855
gene id: 1461582:RZ44_RS06855
uniprot id: A0A078M8A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1461582:RZ44 RS08850
gene id: 1461582:RZ44_RS08850
uniprot id: A0A078MBK5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1461582:RZ44 RS05665
gene id: 1461582:RZ44_RS05665
uniprot id: A0A078M6H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1461582:RZ44 RS07885
gene id: 1461582:RZ44_RS07885
uniprot id: A0A078M7G8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1461582:RZ44 RS06010
gene id: 1461582:RZ44_RS06010
uniprot id: A0A078M766
names: Similarity
messages: Belongs to the UPF0312 family.

1461582:RZ44 RS04690
gene id: 1461582:RZ44_RS04690
uniprot id: A0A078M577
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1461582:RZ44 RS02380
gene id: 1461582:RZ44_RS02380
uniprot id: A0A078M285
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1461582:RZ44 RS08020
gene id: 1461582:RZ44_RS08020
uniprot id: A0A078M7U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.