1458425:SRAA RS10775
gene id: 1458425:SRAA_RS10775
uniprot id: A0A060NSW7
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1458425:SRAA RS08620
gene id: 1458425:SRAA_RS08620
uniprot id: A0A060NJ97
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1458425:SRAA RS01085
gene id: 1458425:SRAA_RS01085
uniprot id: A0A060NMC9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1458425:SRAA RS03440
gene id: 1458425:SRAA_RS03440
uniprot id: A0A060NLZ2
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1458425:SRAA RS02590
gene id: 1458425:SRAA_RS02590
uniprot id: A0A060NH61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1458425:SRAA RS09140
gene id: 1458425:SRAA_RS09140
uniprot id: A0A060NK62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GmhB family.
messages: Cytoplasm

1458425:SRAA RS10910
gene id: 1458425:SRAA_RS10910
uniprot id: A0A060NIQ8
names: Similarity
messages: Belongs to the HepT RNase toxin family.

1458425:SRAA RS04955
gene id: 1458425:SRAA_RS04955
uniprot id: A0A060NIS7
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS00070
gene id: 1458425:SRAA_RS00070
uniprot id: A0A060NKD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1458425:SRAA RS03570
gene id: 1458425:SRAA_RS03570
uniprot id: A0A060NM21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1458425:SRAA RS07405
gene id: 1458425:SRAA_RS07405
uniprot id: A0A060NHI6
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS02360
gene id: 1458425:SRAA_RS02360
uniprot id: A0A060NHU3
names: Similarity
messages: Belongs to the type III secretion exporter family.

1458425:SRAA RS01505
gene id: 1458425:SRAA_RS01505
uniprot id: A0A060NML4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1458425:SRAA RS03370
gene id: 1458425:SRAA_RS03370
uniprot id: A0A060NNN0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1458425:SRAA RS03620
gene id: 1458425:SRAA_RS03620
uniprot id: A0A060NM29
names: Similarity
messages: Belongs to the skp family.

1458425:SRAA RS02960
gene id: 1458425:SRAA_RS02960
uniprot id: A0A060NNG7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1458425:SRAA RS03030
gene id: 1458425:SRAA_RS03030
uniprot id: A0A060NI00
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1458425:SRAA RS10615
gene id: 1458425:SRAA_RS10615
uniprot id: A0A060NK04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1458425:SRAA RS11205
gene id: 1458425:SRAA_RS11205
uniprot id: A0A060NIT9
names: Similarity
messages: Belongs to the NTE family.

1458425:SRAA RS07085
gene id: 1458425:SRAA_RS07085
uniprot id: A0A060NQT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1458425:SRAA RS08805
gene id: 1458425:SRAA_RS08805
uniprot id: A0A060NPZ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1458425:SRAA RS01685
gene id: 1458425:SRAA_RS01685
uniprot id: A0A060NHI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1458425:SRAA RS09095
gene id: 1458425:SRAA_RS09095
uniprot id: A0A060NI13
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1458425:SRAA RS00665
gene id: 1458425:SRAA_RS00665
uniprot id: A0A060NF78
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1458425:SRAA RS06800
gene id: 1458425:SRAA_RS06800
uniprot id: A0A060NH62
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1458425:SRAA RS09035
gene id: 1458425:SRAA_RS09035
uniprot id: A0A060NRX4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1458425:SRAA RS08965
gene id: 1458425:SRAA_RS08965
uniprot id: A0A060NK38
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1458425:SRAA RS03950
gene id: 1458425:SRAA_RS03950
uniprot id: A0A060NHM2
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1458425:SRAA RS11125
gene id: 1458425:SRAA_RS11125
uniprot id: A0A060NL31
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS08430
gene id: 1458425:SRAA_RS08430
uniprot id: A0A060NPS5
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1458425:SRAA RS08495
gene id: 1458425:SRAA_RS08495
uniprot id: A0A060NJ83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.

1458425:SRAA RS10870
gene id: 1458425:SRAA_RS10870
uniprot id: A0A060NR46
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1458425:SRAA RS08605
gene id: 1458425:SRAA_RS08605
uniprot id: A0A060NRN8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1458425:SRAA RS00425
gene id: 1458425:SRAA_RS00425
uniprot id: A0A060NH20
names: Similarity
messages: Belongs to the UPF0102 family.

1458425:SRAA RS10385
gene id: 1458425:SRAA_RS10385
uniprot id: A0A060NIL1
names: Similarity
messages: Belongs to the HypE family.

1458425:SRAA RS06180
gene id: 1458425:SRAA_RS06180
uniprot id: A0A060NJ47
names: Similarity
messages: Belongs to the glyoxalase I family.

1458425:SRAA RS06820
gene id: 1458425:SRAA_RS06820
uniprot id: A0A060NJC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1458425:SRAA RS07010
gene id: 1458425:SRAA_RS07010
uniprot id: A0A060NP13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1458425:SRAA RS02465
gene id: 1458425:SRAA_RS02465
uniprot id: A0A060NFU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1458425:SRAA RS03830
gene id: 1458425:SRAA_RS03830
uniprot id: A0A060NNX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1458425:SRAA RS06485
gene id: 1458425:SRAA_RS06485
uniprot id: A0A060NJ84
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1458425:SRAA RS07065
gene id: 1458425:SRAA_RS07065
uniprot id: A0A060NJF8
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1458425:SRAA RS05475
gene id: 1458425:SRAA_RS05475
uniprot id: A0A060NIW8
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1458425:SRAA RS01205
gene id: 1458425:SRAA_RS01205
uniprot id: A0A060NMF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

1458425:SRAA RS11210
gene id: 1458425:SRAA_RS11210
uniprot id: A0A060NK73
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS00045
gene id: 1458425:SRAA_RS00045
uniprot id: A0A060NKD0
names: Similarity
messages: Belongs to the UPF0250 family.

1458425:SRAA RS06380
gene id: 1458425:SRAA_RS06380
uniprot id: A0A060NQD5
names: Similarity
messages: Belongs to the thioredoxin family.

1458425:SRAA RS11160
gene id: 1458425:SRAA_RS11160
uniprot id: A0A060NK66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1458425:SRAA RS11770
gene id: 1458425:SRAA_RS11770
uniprot id: A0A060NTG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1458425:SRAA RS00420
gene id: 1458425:SRAA_RS00420
uniprot id: A0A060NM07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1458425:SRAA RS02640
gene id: 1458425:SRAA_RS02640
uniprot id: A0A060NH66
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1458425:SRAA RS10960
gene id: 1458425:SRAA_RS10960
uniprot id: A0A060NK42
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1458425:SRAA RS00035
gene id: 1458425:SRAA_RS00035
uniprot id: A0A060NF27
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1458425:SRAA RS02730
gene id: 1458425:SRAA_RS02730
uniprot id: A0A060NHX9
names: Similarity
messages: Belongs to the HesB/IscA family.

1458425:SRAA RS05000
gene id: 1458425:SRAA_RS05000
uniprot id: A0A060NPP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1458425:SRAA RS10085
gene id: 1458425:SRAA_RS10085
uniprot id: A0A060NKP3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1458425:SRAA RS02270
gene id: 1458425:SRAA_RS02270
uniprot id: A0A060NH14
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1458425:SRAA RS05210
gene id: 1458425:SRAA_RS05210
uniprot id: A0A060NPR9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1458425:SRAA RS08230
gene id: 1458425:SRAA_RS08230
uniprot id: A0A060NJ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

1458425:SRAA RS08025
gene id: 1458425:SRAA_RS08025
uniprot id: A0A060NJ36
names: Similarity
messages: Belongs to the DEAD box helicase family.

1458425:SRAA RS00080
gene id: 1458425:SRAA_RS00080
uniprot id: A0A060NGZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1458425:SRAA RS03760
gene id: 1458425:SRAA_RS03760
uniprot id: A0A060NI88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1458425:SRAA RS04270
gene id: 1458425:SRAA_RS04270
uniprot id: A0A060NIG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

1458425:SRAA RS02295
gene id: 1458425:SRAA_RS02295
uniprot id: A0A060NH26
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1458425:SRAA RS02145
gene id: 1458425:SRAA_RS02145
uniprot id: A0A060NGZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1458425:SRAA RS01345
gene id: 1458425:SRAA_RS01345
uniprot id: A0A060NGN8
names: Similarity
messages: Belongs to the glutamate synthase family.

1458425:SRAA RS00040
gene id: 1458425:SRAA_RS00040
uniprot id: A0A060NG91
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1458425:SRAA RS01885
gene id: 1458425:SRAA_RS01885
uniprot id: A0A060NHL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

1458425:SRAA RS02855
gene id: 1458425:SRAA_RS02855
uniprot id: A0A060NLP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1458425:SRAA RS05590
gene id: 1458425:SRAA_RS05590
uniprot id: A0A060NI72
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.

1458425:SRAA RS11040
gene id: 1458425:SRAA_RS11040
uniprot id: A0A060NR74
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1458425:SRAA RS05425
gene id: 1458425:SRAA_RS05425
uniprot id: A0A060NI57
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS10930
gene id: 1458425:SRAA_RS10930
uniprot id: A0A060NKZ7
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1458425:SRAA RS11645
gene id: 1458425:SRAA_RS11645
uniprot id: A0A060NRJ8
names: Similarity
messages: Belongs to the pyruvate kinase family.

1458425:SRAA RS05420
gene id: 1458425:SRAA_RS05420
uniprot id: A0A060NGQ4
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS07715
gene id: 1458425:SRAA_RS07715
uniprot id: A0A060NHL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1458425:SRAA RS08830
gene id: 1458425:SRAA_RS08830
uniprot id: A0A060NQ04
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1458425:SRAA RS08445
gene id: 1458425:SRAA_RS08445
uniprot id: A0A060NHT7
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

1458425:SRAA RS09190
gene id: 1458425:SRAA_RS09190
uniprot id: A0A060NK70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1458425:SRAA RS04030
gene id: 1458425:SRAA_RS04030
uniprot id: A0A060NHN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1458425:SRAA RS00555
gene id: 1458425:SRAA_RS00555
uniprot id: A0A060NF68
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1458425:SRAA RS08470
gene id: 1458425:SRAA_RS08470
uniprot id: A0A060NHT9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1458425:SRAA RS04330
gene id: 1458425:SRAA_RS04330
uniprot id: A0A060NHR7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1458425:SRAA RS10645
gene id: 1458425:SRAA_RS10645
uniprot id: A0A060NR13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1458425:SRAA RS10950
gene id: 1458425:SRAA_RS10950
uniprot id: A0A060NL01
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1458425:SRAA RS02430
gene id: 1458425:SRAA_RS02430
uniprot id: A0A060NN89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1458425:SRAA RS11445
gene id: 1458425:SRAA_RS11445
uniprot id: A0A060NT99
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1458425:SRAA RS04035
gene id: 1458425:SRAA_RS04035
uniprot id: A0A060NMB0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1458425:SRAA RS03315
gene id: 1458425:SRAA_RS03315
uniprot id: A0A060NHE7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1458425:SRAA RS03815
gene id: 1458425:SRAA_RS03815
uniprot id: A0A060NG44
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1458425:SRAA RS08325
gene id: 1458425:SRAA_RS08325
uniprot id: A0A060NHS7
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1458425:SRAA RS08085
gene id: 1458425:SRAA_RS08085
uniprot id: A0A060NRE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1458425:SRAA RS07575
gene id: 1458425:SRAA_RS07575
uniprot id: A0A060NR57
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1458425:SRAA RS05830
gene id: 1458425:SRAA_RS05830
uniprot id: A0A060NNA0
names: Similarity
messages: Belongs to the peptidase M1 family.

1458425:SRAA RS05980
gene id: 1458425:SRAA_RS05980
uniprot id: A0A060NNC8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1458425:SRAA RS00210
gene id: 1458425:SRAA_RS00210
uniprot id: A0A060NGA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1458425:SRAA RS00485
gene id: 1458425:SRAA_RS00485
uniprot id: A0A060NGD5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1458425:SRAA RS10545
gene id: 1458425:SRAA_RS10545
uniprot id: A0A060NR00
names: Subcellular Location Annotation
messages: Cytoplasm

1458425:SRAA RS02500
gene id: 1458425:SRAA_RS02500
uniprot id: A0A060NLJ9
names: Similarity
messages: Belongs to the YoeB family.

1458425:SRAA RS03165
gene id: 1458425:SRAA_RS03165
uniprot id: A0A060NHC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1458425:SRAA RS08195
gene id: 1458425:SRAA_RS08195
uniprot id: A0A060NJT5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1458425:SRAA RS06175
gene id: 1458425:SRAA_RS06175
uniprot id: A0A060NQ92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1458425:SRAA RS09295
gene id: 1458425:SRAA_RS09295
uniprot id: A0A060NI44
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1458425:SRAA RS00260
gene id: 1458425:SRAA_RS00260
uniprot id: A0A060NF44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

1458425:SRAA RS04720
gene id: 1458425:SRAA_RS04720
uniprot id: A0A060NPG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1458425:SRAA RS01325
gene id: 1458425:SRAA_RS01325
uniprot id: A0A060NKW0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1458425:SRAA RS10900
gene id: 1458425:SRAA_RS10900
uniprot id: A0A060NSZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1458425:SRAA RS06655
gene id: 1458425:SRAA_RS06655
uniprot id: A0A060NQI9
names: Similarity
messages: Belongs to the histone deacetylase family.

1458425:SRAA RS06900
gene id: 1458425:SRAA_RS06900
uniprot id: A0A060NIP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1458425:SRAA RS09620
gene id: 1458425:SRAA_RS09620
uniprot id: A0A060NKE1
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS04810
gene id: 1458425:SRAA_RS04810
uniprot id: A0A060NHY0
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1458425:SRAA RS00365
gene id: 1458425:SRAA_RS00365
uniprot id: A0A060NKH0
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1458425:SRAA RS07605
gene id: 1458425:SRAA_RS07605
uniprot id: A0A060NJN4
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1458425:SRAA RS00805
gene id: 1458425:SRAA_RS00805
uniprot id: A0A060NH58
names: Similarity
messages: Belongs to the universal stress protein A family.

1458425:SRAA RS01670
gene id: 1458425:SRAA_RS01670
uniprot id: A0A060NGT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1458425:SRAA RS01250
gene id: 1458425:SRAA_RS01250
uniprot id: A0A060NKU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1458425:SRAA RS11940
gene id: 1458425:SRAA_RS11940
uniprot id: A0A060NJ38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1458425:SRAA RS06350
gene id: 1458425:SRAA_RS06350
uniprot id: A0A060NNK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1458425:SRAA RS03610
gene id: 1458425:SRAA_RS03610
uniprot id: A0A060NG26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1458425:SRAA RS07585
gene id: 1458425:SRAA_RS07585
uniprot id: A0A060NHK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

1458425:SRAA RS05885
gene id: 1458425:SRAA_RS05885
uniprot id: A0A060NQ28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1458425:SRAA RS02225
gene id: 1458425:SRAA_RS02225
uniprot id: A0A060NLD7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1458425:SRAA RS05515
gene id: 1458425:SRAA_RS05515
uniprot id: A0A060NN55
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

1458425:SRAA RS07860
gene id: 1458425:SRAA_RS07860
uniprot id: A0A060NJQ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1458425:SRAA RS05625
gene id: 1458425:SRAA_RS05625
uniprot id: A0A060NN69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1458425:SRAA RS03275
gene id: 1458425:SRAA_RS03275
uniprot id: A0A060NNL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1458425:SRAA RS06355
gene id: 1458425:SRAA_RS06355
uniprot id: A0A060NQC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1458425:SRAA RS06215
gene id: 1458425:SRAA_RS06215
uniprot id: A0A060NIE6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1458425:SRAA RS08270
gene id: 1458425:SRAA_RS08270
uniprot id: A0A060NJU5
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS03485
gene id: 1458425:SRAA_RS03485
uniprot id: A0A060NHG7
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1458425:SRAA RS05200
gene id: 1458425:SRAA_RS05200
uniprot id: A0A060NI35
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1458425:SRAA RS10995
gene id: 1458425:SRAA_RS10995
uniprot id: A0A060NT11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1458425:SRAA RS03300
gene id: 1458425:SRAA_RS03300
uniprot id: A0A060NNL7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1458425:SRAA RS06775
gene id: 1458425:SRAA_RS06775
uniprot id: A0A060NH57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1458425:SRAA RS04805
gene id: 1458425:SRAA_RS04805
uniprot id: A0A060NGG7
names: Similarity
messages: Belongs to the PstS family.

1458425:SRAA RS07850
gene id: 1458425:SRAA_RS07850
uniprot id: A0A060NPI9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1458425:SRAA RS02415
gene id: 1458425:SRAA_RS02415
uniprot id: A0A060NFT8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1458425:SRAA RS00065
gene id: 1458425:SRAA_RS00065
uniprot id: A0A060NG93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1458425:SRAA RS05775
gene id: 1458425:SRAA_RS05775
uniprot id: A0A060NI89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

1458425:SRAA RS05075
gene id: 1458425:SRAA_RS05075
uniprot id: A0A060NI23
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1458425:SRAA RS06980
gene id: 1458425:SRAA_RS06980
uniprot id: A0A060NIQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1458425:SRAA RS10705
gene id: 1458425:SRAA_RS10705
uniprot id: A0A060NKW2
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1458425:SRAA RS10390
gene id: 1458425:SRAA_RS10390
uniprot id: A0A060NJX8
names: Similarity
messages: Belongs to the HypD family.

1458425:SRAA RS05495
gene id: 1458425:SRAA_RS05495
uniprot id: A0A060NPW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1458425:SRAA RS02130
gene id: 1458425:SRAA_RS02130
uniprot id: A0A060NMZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1458425:SRAA RS11685
gene id: 1458425:SRAA_RS11685
uniprot id: A0A060NJ02
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1458425:SRAA RS04635
gene id: 1458425:SRAA_RS04635
uniprot id: A0A060NHV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1458425:SRAA RS03680
gene id: 1458425:SRAA_RS03680
uniprot id: A0A060NI77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1458425:SRAA RS00270
gene id: 1458425:SRAA_RS00270
uniprot id: A0A060NKF8
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1458425:SRAA RS02645
gene id: 1458425:SRAA_RS02645
uniprot id: A0A060NLM0
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1458425:SRAA RS00120
gene id: 1458425:SRAA_RS00120
uniprot id: A0A060NKD8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1458425:SRAA RS08475
gene id: 1458425:SRAA_RS08475
uniprot id: A0A060NPT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1458425:SRAA RS08600
gene id: 1458425:SRAA_RS08600
uniprot id: A0A060NPV9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1458425:SRAA RS00115
gene id: 1458425:SRAA_RS00115
uniprot id: A0A060NG97
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

1458425:SRAA RS10915
gene id: 1458425:SRAA_RS10915
uniprot id: A0A060NK37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1458425:SRAA RS10595
gene id: 1458425:SRAA_RS10595
uniprot id: A0A060NR07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1458425:SRAA RS09985
gene id: 1458425:SRAA_RS09985
uniprot id: A0A060NKN1
names: Similarity
messages: Belongs to the creatininase superfamily.

1458425:SRAA RS05005
gene id: 1458425:SRAA_RS05005
uniprot id: A0A060NIT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1458425:SRAA RS08100
gene id: 1458425:SRAA_RS08100
uniprot id: A0A060NJ43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1458425:SRAA RS10455
gene id: 1458425:SRAA_RS10455
uniprot id: A0A060NKT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1458425:SRAA RS00595
gene id: 1458425:SRAA_RS00595
uniprot id: A0A060NM34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

1458425:SRAA RS03765
gene id: 1458425:SRAA_RS03765
uniprot id: A0A060NG40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1458425:SRAA RS00440
gene id: 1458425:SRAA_RS00440
uniprot id: A0A060NKI0
names: Similarity
messages: Belongs to the GSP E family.

1458425:SRAA RS08050
gene id: 1458425:SRAA_RS08050
uniprot id: A0A060NJ37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1458425:SRAA RS02975
gene id: 1458425:SRAA_RS02975
uniprot id: A0A060NHA5
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1458425:SRAA RS01510
gene id: 1458425:SRAA_RS01510
uniprot id: A0A060NHG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1458425:SRAA RS00610
gene id: 1458425:SRAA_RS00610
uniprot id: A0A060NGE7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1458425:SRAA RS00240
gene id: 1458425:SRAA_RS00240
uniprot id: A0A060NGB0
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS02925
gene id: 1458425:SRAA_RS02925
uniprot id: A0A060NLQ7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1458425:SRAA RS10540
gene id: 1458425:SRAA_RS10540
uniprot id: A0A060NJZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1458425:SRAA RS01880
gene id: 1458425:SRAA_RS01880
uniprot id: A0A060NMT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TraY family.
messages: Cytoplasm

1458425:SRAA RS01625
gene id: 1458425:SRAA_RS01625
uniprot id: A0A060NL19
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1458425:SRAA RS09740
gene id: 1458425:SRAA_RS09740
uniprot id: A0A060NSD1
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1458425:SRAA RS09715
gene id: 1458425:SRAA_RS09715
uniprot id: A0A060NQJ9
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS07100
gene id: 1458425:SRAA_RS07100
uniprot id: A0A060NIR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

1458425:SRAA RS00835
gene id: 1458425:SRAA_RS00835
uniprot id: A0A060NF92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1458425:SRAA RS10400
gene id: 1458425:SRAA_RS10400
uniprot id: A0A060NSQ6
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

1458425:SRAA RS03380
gene id: 1458425:SRAA_RS03380
uniprot id: A0A060NG11
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1458425:SRAA RS03690
gene id: 1458425:SRAA_RS03690
uniprot id: A0A060NHJ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1458425:SRAA RS06030
gene id: 1458425:SRAA_RS06030
uniprot id: A0A060NJ29
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1458425:SRAA RS04525
gene id: 1458425:SRAA_RS04525
uniprot id: A0A060NIK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1458425:SRAA RS01495
gene id: 1458425:SRAA_RS01495
uniprot id: A0A060NGQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1458425:SRAA RS06430
gene id: 1458425:SRAA_RS06430
uniprot id: A0A060NQE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1458425:SRAA RS04985
gene id: 1458425:SRAA_RS04985
uniprot id: A0A060NGL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1458425:SRAA RS10535
gene id: 1458425:SRAA_RS10535
uniprot id: A0A060NIM6
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS05665
gene id: 1458425:SRAA_RS05665
uniprot id: A0A060NGS8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1458425:SRAA RS07510
gene id: 1458425:SRAA_RS07510
uniprot id: A0A060NHJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

1458425:SRAA RS04305
gene id: 1458425:SRAA_RS04305
uniprot id: A0A060NHR6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1458425:SRAA RS10570
gene id: 1458425:SRAA_RS10570
uniprot id: A0A060NR04
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1458425:SRAA RS10445
gene id: 1458425:SRAA_RS10445
uniprot id: A0A060NQY6
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1458425:SRAA RS08710
gene id: 1458425:SRAA_RS08710
uniprot id: A0A060NK07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1458425:SRAA RS06530
gene id: 1458425:SRAA_RS06530
uniprot id: A0A060NNP3
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

1458425:SRAA RS00060
gene id: 1458425:SRAA_RS00060
uniprot id: A0A060NF30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1458425:SRAA RS03715
gene id: 1458425:SRAA_RS03715
uniprot id: A0A060NG35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1458425:SRAA RS08510
gene id: 1458425:SRAA_RS08510
uniprot id: A0A060NJY0
names: Similarity
messages: Belongs to the TrpF family.

1458425:SRAA RS06600
gene id: 1458425:SRAA_RS06600
uniprot id: A0A060NIJ8
names: Similarity
messages: Belongs to the MoaD family.

1458425:SRAA RS09440
gene id: 1458425:SRAA_RS09440
uniprot id: A0A060NKA2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1458425:SRAA RS08915
gene id: 1458425:SRAA_RS08915
uniprot id: A0A060NK32
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1458425:SRAA RS00170
gene id: 1458425:SRAA_RS00170
uniprot id: A0A060NLW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1458425:SRAA RS05080
gene id: 1458425:SRAA_RS05080
uniprot id: A0A060NMZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1458425:SRAA RS00860
gene id: 1458425:SRAA_RS00860
uniprot id: A0A060NF94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1458425:SRAA RS01200
gene id: 1458425:SRAA_RS01200
uniprot id: A0A060NKU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1458425:SRAA RS01115
gene id: 1458425:SRAA_RS01115
uniprot id: A0A060NFB8
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1458425:SRAA RS03115
gene id: 1458425:SRAA_RS03115
uniprot id: A0A060NHC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1458425:SRAA RS09010
gene id: 1458425:SRAA_RS09010
uniprot id: A0A060NRW9
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS05880
gene id: 1458425:SRAA_RS05880
uniprot id: A0A060NNA9
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS06230
gene id: 1458425:SRAA_RS06230
uniprot id: A0A060NJ54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein.
messages: Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.

1458425:SRAA RS04535
gene id: 1458425:SRAA_RS04535
uniprot id: A0A060NHT8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1458425:SRAA RS01665
gene id: 1458425:SRAA_RS01665
uniprot id: A0A060NFH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1458425:SRAA RS03535
gene id: 1458425:SRAA_RS03535
uniprot id: A0A060NG21
names: Similarity
messages: Belongs to the YggT family.

1458425:SRAA RS07830
gene id: 1458425:SRAA_RS07830
uniprot id: A0A060NR97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1458425:SRAA RS10710
gene id: 1458425:SRAA_RS10710
uniprot id: A0A060NIP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1458425:SRAA RS03260
gene id: 1458425:SRAA_RS03260
uniprot id: A0A060NG00
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1458425:SRAA RS00185
gene id: 1458425:SRAA_RS00185
uniprot id: A0A060NGA4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1458425:SRAA RS05470
gene id: 1458425:SRAA_RS05470
uniprot id: A0A060NPW0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS09015
gene id: 1458425:SRAA_RS09015
uniprot id: A0A060NK45
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

1458425:SRAA RS09865
gene id: 1458425:SRAA_RS09865
uniprot id: A0A060NSH8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1458425:SRAA RS03960
gene id: 1458425:SRAA_RS03960
uniprot id: A0A060NNZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1458425:SRAA RS10265
gene id: 1458425:SRAA_RS10265
uniprot id: A0A060NJW4
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS00050
gene id: 1458425:SRAA_RS00050
uniprot id: A0A060NLU5
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS09580
gene id: 1458425:SRAA_RS09580
uniprot id: A0A060NJK9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1458425:SRAA RS00560
gene id: 1458425:SRAA_RS00560
uniprot id: A0A060NGE2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1458425:SRAA RS08185
gene id: 1458425:SRAA_RS08185
uniprot id: A0A060NPN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1458425:SRAA RS01720
gene id: 1458425:SRAA_RS01720
uniprot id: A0A060NGT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1458425:SRAA RS02005
gene id: 1458425:SRAA_RS02005
uniprot id: A0A060NMW5
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

1458425:SRAA RS05310
gene id: 1458425:SRAA_RS05310
uniprot id: A0A060NN28
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1458425:SRAA RS04760
gene id: 1458425:SRAA_RS04760
uniprot id: A0A060NHX2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1458425:SRAA RS00915
gene id: 1458425:SRAA_RS00915
uniprot id: A0A060NM92
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1458425:SRAA RS11430
gene id: 1458425:SRAA_RS11430
uniprot id: A0A060NIW4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1458425:SRAA RS02085
gene id: 1458425:SRAA_RS02085
uniprot id: A0A060NHP7
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1458425:SRAA RS01940
gene id: 1458425:SRAA_RS01940
uniprot id: A0A060NFL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1458425:SRAA RS07905
gene id: 1458425:SRAA_RS07905
uniprot id: A0A060NRB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1458425:SRAA RS08645
gene id: 1458425:SRAA_RS08645
uniprot id: A0A060NJA0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS03270
gene id: 1458425:SRAA_RS03270
uniprot id: A0A060NLV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1458425:SRAA RS00650
gene id: 1458425:SRAA_RS00650
uniprot id: A0A060NH38
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1458425:SRAA RS02740
gene id: 1458425:SRAA_RS02740
uniprot id: A0A060NH78
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

1458425:SRAA RS08590
gene id: 1458425:SRAA_RS08590
uniprot id: A0A060NHV4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1458425:SRAA RS11330
gene id: 1458425:SRAA_RS11330
uniprot id: A0A060NIV4
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1458425:SRAA RS03205
gene id: 1458425:SRAA_RS03205
uniprot id: A0A060NI19
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1458425:SRAA RS04150
gene id: 1458425:SRAA_RS04150
uniprot id: A0A060NIE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1458425:SRAA RS08275
gene id: 1458425:SRAA_RS08275
uniprot id: A0A060NHS4
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS06200
gene id: 1458425:SRAA_RS06200
uniprot id: A0A060NQ97
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1458425:SRAA RS06825
gene id: 1458425:SRAA_RS06825
uniprot id: A0A060NH67
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1458425:SRAA RS10665
gene id: 1458425:SRAA_RS10665
uniprot id: A0A060NK09
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1458425:SRAA RS03635
gene id: 1458425:SRAA_RS03635
uniprot id: A0A060NG29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1458425:SRAA RS00400
gene id: 1458425:SRAA_RS00400
uniprot id: A0A060NH18
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS04595
gene id: 1458425:SRAA_RS04595
uniprot id: A0A060NPC8
names: Similarity
messages: Belongs to the HepT RNase toxin family.

1458425:SRAA RS00530
gene id: 1458425:SRAA_RS00530
uniprot id: A0A060NF67
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1458425:SRAA RS06685
gene id: 1458425:SRAA_RS06685
uniprot id: A0A060NJA7
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS07725
gene id: 1458425:SRAA_RS07725
uniprot id: A0A060NPG9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1458425:SRAA RS06625
gene id: 1458425:SRAA_RS06625
uniprot id: A0A060NNR8
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1458425:SRAA RS08015
gene id: 1458425:SRAA_RS08015
uniprot id: A0A060NJR7
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS02170
gene id: 1458425:SRAA_RS02170
uniprot id: A0A060NGZ8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1458425:SRAA RS04640
gene id: 1458425:SRAA_RS04640
uniprot id: A0A060NMP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1458425:SRAA RS01245
gene id: 1458425:SRAA_RS01245
uniprot id: A0A060NGM4
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1458425:SRAA RS02040
gene id: 1458425:SRAA_RS02040
uniprot id: A0A060NFM8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1458425:SRAA RS03565
gene id: 1458425:SRAA_RS03565
uniprot id: A0A060NHH5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1458425:SRAA RS11605
gene id: 1458425:SRAA_RS11605
uniprot id: A0A060NLB6
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1458425:SRAA RS08530
gene id: 1458425:SRAA_RS08530
uniprot id: A0A060NRM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

1458425:SRAA RS11750
gene id: 1458425:SRAA_RS11750
uniprot id: A0A060NLD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1458425:SRAA RS10610
gene id: 1458425:SRAA_RS10610
uniprot id: A0A060NIN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1458425:SRAA RS05905
gene id: 1458425:SRAA_RS05905
uniprot id: A0A060NNB3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1458425:SRAA RS11335
gene id: 1458425:SRAA_RS11335
uniprot id: A0A060NK87
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1458425:SRAA RS08570
gene id: 1458425:SRAA_RS08570
uniprot id: A0A060NJ91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1458425:SRAA RS09030
gene id: 1458425:SRAA_RS09030
uniprot id: A0A060NQ44
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1458425:SRAA RS12505
gene id: 1458425:SRAA_RS12505
uniprot id: A0A060NPF1
names: Similarity
messages: Belongs to the UPF0246 family.

1458425:SRAA RS02790
gene id: 1458425:SRAA_RS02790
uniprot id: A0A060NHY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1458425:SRAA RS09850
gene id: 1458425:SRAA_RS09850
uniprot id: A0A060NID8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1458425:SRAA RS08815
gene id: 1458425:SRAA_RS08815
uniprot id: A0A060NK19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1458425:SRAA RS10575
gene id: 1458425:SRAA_RS10575
uniprot id: A0A060NST5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1458425:SRAA RS03510
gene id: 1458425:SRAA_RS03510
uniprot id: A0A060NHH0
names: Similarity
messages: Belongs to the GbsR family.

1458425:SRAA RS00215
gene id: 1458425:SRAA_RS00215
uniprot id: A0A060NKF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1458425:SRAA RS03655
gene id: 1458425:SRAA_RS03655
uniprot id: A0A060NI74
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1458425:SRAA RS06445
gene id: 1458425:SRAA_RS06445
uniprot id: A0A060NIH5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1458425:SRAA RS06140
gene id: 1458425:SRAA_RS06140
uniprot id: A0A060NID7
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1458425:SRAA RS08395
gene id: 1458425:SRAA_RS08395
uniprot id: A0A060NHT4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1458425:SRAA RS00705
gene id: 1458425:SRAA_RS00705
uniprot id: A0A060NM54
names: Similarity
messages: Belongs to the universal stress protein A family.

1458425:SRAA RS08625
gene id: 1458425:SRAA_RS08625
uniprot id: A0A060NPW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1458425:SRAA RS11920
gene id: 1458425:SRAA_RS11920
uniprot id: A0A060NKI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1458425:SRAA RS12390
gene id: 1458425:SRAA_RS12390
uniprot id: A0A060NMN9
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

1458425:SRAA RS08820
gene id: 1458425:SRAA_RS08820
uniprot id: A0A060NHY2
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1458425:SRAA RS10065
gene id: 1458425:SRAA_RS10065
uniprot id: A0A060NII3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS04185
gene id: 1458425:SRAA_RS04185
uniprot id: A0A060NHQ2
names: Similarity
messages: Belongs to the peptidase S41A family.

1458425:SRAA RS09080
gene id: 1458425:SRAA_RS09080
uniprot id: A0A060NQ56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1458425:SRAA RS01725
gene id: 1458425:SRAA_RS01725
uniprot id: A0A060NL40
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1458425:SRAA RS01400
gene id: 1458425:SRAA_RS01400
uniprot id: A0A060NKX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS00900
gene id: 1458425:SRAA_RS00900
uniprot id: A0A060NH71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS06100
gene id: 1458425:SRAA_RS06100
uniprot id: A0A060NQ75
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1458425:SRAA RS09730
gene id: 1458425:SRAA_RS09730
uniprot id: A0A060NIB6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1458425:SRAA RS04240
gene id: 1458425:SRAA_RS04240
uniprot id: A0A060NMF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1458425:SRAA RS09780
gene id: 1458425:SRAA_RS09780
uniprot id: A0A060NJP2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1458425:SRAA RS03125
gene id: 1458425:SRAA_RS03125
uniprot id: A0A060NNJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PriB family.
messages: Binds single-stranded DNA at the primosome assembly site (PAS).
messages: Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.

1458425:SRAA RS08895
gene id: 1458425:SRAA_RS08895
uniprot id: A0A060NHY9
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS00510
gene id: 1458425:SRAA_RS00510
uniprot id: A0A060NGD7
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS02725
gene id: 1458425:SRAA_RS02725
uniprot id: A0A060NNC9
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

1458425:SRAA RS11380
gene id: 1458425:SRAA_RS11380
uniprot id: A0A060NIV9
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS03080
gene id: 1458425:SRAA_RS03080
uniprot id: A0A060NI04
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1458425:SRAA RS09245
gene id: 1458425:SRAA_RS09245
uniprot id: A0A060NI36
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1458425:SRAA RS07555
gene id: 1458425:SRAA_RS07555
uniprot id: A0A060NJN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1458425:SRAA RS00225
gene id: 1458425:SRAA_RS00225
uniprot id: A0A060NH03
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1458425:SRAA RS01745
gene id: 1458425:SRAA_RS01745
uniprot id: A0A060NGU2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1458425:SRAA RS08905
gene id: 1458425:SRAA_RS08905
uniprot id: A0A060NQ17
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1458425:SRAA RS04565
gene id: 1458425:SRAA_RS04565
uniprot id: A0A060NMM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1458425:SRAA RS10270
gene id: 1458425:SRAA_RS10270
uniprot id: A0A060NQW0
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS00155
gene id: 1458425:SRAA_RS00155
uniprot id: A0A060NF38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1458425:SRAA RS07735
gene id: 1458425:SRAA_RS07735
uniprot id: A0A060NJP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1458425:SRAA RS00350
gene id: 1458425:SRAA_RS00350
uniprot id: A0A060NH15
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS00755
gene id: 1458425:SRAA_RS00755
uniprot id: A0A060NM60
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1458425:SRAA RS00335
gene id: 1458425:SRAA_RS00335
uniprot id: A0A060NGC0
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1458425:SRAA RS09515
gene id: 1458425:SRAA_RS09515
uniprot id: A0A060NS72
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1458425:SRAA RS07435
gene id: 1458425:SRAA_RS07435
uniprot id: A0A060NIY0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1458425:SRAA RS09560
gene id: 1458425:SRAA_RS09560
uniprot id: A0A060NQG4
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1458425:SRAA RS01255
gene id: 1458425:SRAA_RS01255
uniprot id: A0A060NMG5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1458425:SRAA RS02915
gene id: 1458425:SRAA_RS02915
uniprot id: A0A060NFX2
names: Subcellular Location Annotation
messages: Cytoplasm

1458425:SRAA RS03045
gene id: 1458425:SRAA_RS03045
uniprot id: A0A060NLR9
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS00295
gene id: 1458425:SRAA_RS00295
uniprot id: A0A060NKG2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1458425:SRAA RS07035
gene id: 1458425:SRAA_RS07035
uniprot id: A0A060NP20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1458425:SRAA RS04820
gene id: 1458425:SRAA_RS04820
uniprot id: A0A060NPI6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1458425:SRAA RS07140
gene id: 1458425:SRAA_RS07140
uniprot id: A0A060NJG9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1458425:SRAA RS10205
gene id: 1458425:SRAA_RS10205
uniprot id: A0A060NKQ4
names: Similarity
messages: Belongs to the TrpC family.

1458425:SRAA RS11015
gene id: 1458425:SRAA_RS11015
uniprot id: A0A060NR70
names: Similarity
messages: Belongs to the glutamine synthetase family.

1458425:SRAA RS05385
gene id: 1458425:SRAA_RS05385
uniprot id: A0A060NPU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

1458425:SRAA RS09145
gene id: 1458425:SRAA_RS09145
uniprot id: A0A060NI21
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1458425:SRAA RS09550
gene id: 1458425:SRAA_RS09550
uniprot id: A0A060NI82
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1458425:SRAA RS06410
gene id: 1458425:SRAA_RS06410
uniprot id: A0A060NJ75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1458425:SRAA RS06195
gene id: 1458425:SRAA_RS06195
uniprot id: A0A060NNH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1458425:SRAA RS05570
gene id: 1458425:SRAA_RS05570
uniprot id: A0A060NN63
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1458425:SRAA RS05535
gene id: 1458425:SRAA_RS05535
uniprot id: A0A060NI66
names: Similarity
messages: Belongs to the RelE toxin family.

1458425:SRAA RS11135
gene id: 1458425:SRAA_RS11135
uniprot id: A0A060NK63
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1458425:SRAA RS00390
gene id: 1458425:SRAA_RS00390
uniprot id: A0A060NKH4
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1458425:SRAA RS05430
gene id: 1458425:SRAA_RS05430
uniprot id: A0A060NN45
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS01990
gene id: 1458425:SRAA_RS01990
uniprot id: A0A060NFM0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1458425:SRAA RS07520
gene id: 1458425:SRAA_RS07520
uniprot id: A0A060NPD9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

1458425:SRAA RS01390
gene id: 1458425:SRAA_RS01390
uniprot id: A0A060NFD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1458425:SRAA RS07415
gene id: 1458425:SRAA_RS07415
uniprot id: A0A060NPC3
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1458425:SRAA RS05610
gene id: 1458425:SRAA_RS05610
uniprot id: A0A060NIX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1458425:SRAA RS04510
gene id: 1458425:SRAA_RS04510
uniprot id: A0A060NHT5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1458425:SRAA RS02680
gene id: 1458425:SRAA_RS02680
uniprot id: A0A060NHX4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1458425:SRAA RS01160
gene id: 1458425:SRAA_RS01160
uniprot id: A0A060NHB3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1458425:SRAA RS11930
gene id: 1458425:SRAA_RS11930
uniprot id: A0A060NTI5
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1458425:SRAA RS03395
gene id: 1458425:SRAA_RS03395
uniprot id: A0A060NNN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

1458425:SRAA RS04300
gene id: 1458425:SRAA_RS04300
uniprot id: A0A060NG85
names: Cofactor
messages: Can also use Mn(2+) ion.

1458425:SRAA RS10590
gene id: 1458425:SRAA_RS10590
uniprot id: A0A060NK02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1458425:SRAA RS03645
gene id: 1458425:SRAA_RS03645
uniprot id: A0A060NM33
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1458425:SRAA RS09595
gene id: 1458425:SRAA_RS09595
uniprot id: A0A060NKD4
names: Similarity
messages: Belongs to the glutamine synthetase family.

1458425:SRAA RS03365
gene id: 1458425:SRAA_RS03365
uniprot id: A0A060NLX5
names: Similarity
messages: Belongs to the UPF0145 family.

1458425:SRAA RS08525
gene id: 1458425:SRAA_RS08525
uniprot id: A0A060NPU4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1458425:SRAA RS01690
gene id: 1458425:SRAA_RS01690
uniprot id: A0A060NFH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1458425:SRAA RS03400
gene id: 1458425:SRAA_RS03400
uniprot id: A0A060NI42
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1458425:SRAA RS09300
gene id: 1458425:SRAA_RS09300
uniprot id: A0A060NJH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1458425:SRAA RS08505
gene id: 1458425:SRAA_RS08505
uniprot id: A0A060NRL4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS03210
gene id: 1458425:SRAA_RS03210
uniprot id: A0A060NFZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1458425:SRAA RS03575
gene id: 1458425:SRAA_RS03575
uniprot id: A0A060NNS2
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS11260
gene id: 1458425:SRAA_RS11260
uniprot id: A0A060NK81
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS08535
gene id: 1458425:SRAA_RS08535
uniprot id: A0A060NJY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1458425:SRAA RS03725
gene id: 1458425:SRAA_RS03725
uniprot id: A0A060NM47
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1458425:SRAA RS03135
gene id: 1458425:SRAA_RS03135
uniprot id: A0A060NFY9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1458425:SRAA RS00980
gene id: 1458425:SRAA_RS00980
uniprot id: A0A060NGI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1458425:SRAA RS02420
gene id: 1458425:SRAA_RS02420
uniprot id: A0A060NH45
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1458425:SRAA RS01955
gene id: 1458425:SRAA_RS01955
uniprot id: A0A060NMV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1458425:SRAA RS06615
gene id: 1458425:SRAA_RS06615
uniprot id: A0A060NH28
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1458425:SRAA RS00995
gene id: 1458425:SRAA_RS00995
uniprot id: A0A060NH87
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1458425:SRAA RS02905
gene id: 1458425:SRAA_RS02905
uniprot id: A0A060NLQ4
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

1458425:SRAA RS02240
gene id: 1458425:SRAA_RS02240
uniprot id: A0A060NFQ6
names: Similarity
messages: Belongs to the peptidase U62 family.

1458425:SRAA RS05115
gene id: 1458425:SRAA_RS05115
uniprot id: A0A060NIU0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1458425:SRAA RS08640
gene id: 1458425:SRAA_RS08640
uniprot id: A0A060NHW1
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS00010
gene id: 1458425:SRAA_RS00010
uniprot id: A0A060NF26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1458425:SRAA RS09435
gene id: 1458425:SRAA_RS09435
uniprot id: A0A060NS51
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1458425:SRAA RS11550
gene id: 1458425:SRAA_RS11550
uniprot id: A0A060NLA6
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1458425:SRAA RS10470
gene id: 1458425:SRAA_RS10470
uniprot id: A0A060NQY9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.

1458425:SRAA RS07395
gene id: 1458425:SRAA_RS07395
uniprot id: A0A060NR37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1458425:SRAA RS04695
gene id: 1458425:SRAA_RS04695
uniprot id: A0A060NPF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1458425:SRAA RS08235
gene id: 1458425:SRAA_RS08235
uniprot id: A0A060NPP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1458425:SRAA RS03875
gene id: 1458425:SRAA_RS03875
uniprot id: A0A060NM77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1458425:SRAA RS07150
gene id: 1458425:SRAA_RS07150
uniprot id: A0A060NIS2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1458425:SRAA RS04655
gene id: 1458425:SRAA_RS04655
uniprot id: A0A060NGE1
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1458425:SRAA RS00300
gene id: 1458425:SRAA_RS00300
uniprot id: A0A060NLY5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS10620
gene id: 1458425:SRAA_RS10620
uniprot id: A0A060NR10
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1458425:SRAA RS03335
gene id: 1458425:SRAA_RS03335
uniprot id: A0A060NG07
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1458425:SRAA RS04325
gene id: 1458425:SRAA_RS04325
uniprot id: A0A060NG89
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1458425:SRAA RS00825
gene id: 1458425:SRAA_RS00825
uniprot id: A0A060NM73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1458425:SRAA RS03810
gene id: 1458425:SRAA_RS03810
uniprot id: A0A060NI94
names: Similarity
messages: Belongs to the threonine synthase family.

1458425:SRAA RS09805
gene id: 1458425:SRAA_RS09805
uniprot id: A0A060NJP6
names: Similarity
messages: Belongs to the P(II) protein family.

1458425:SRAA RS00330
gene id: 1458425:SRAA_RS00330
uniprot id: A0A060NH12
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1458425:SRAA RS08140
gene id: 1458425:SRAA_RS08140
uniprot id: A0A060NRE8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1458425:SRAA RS06330
gene id: 1458425:SRAA_RS06330
uniprot id: A0A060NQC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1458425:SRAA RS02850
gene id: 1458425:SRAA_RS02850
uniprot id: A0A060NH90
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1458425:SRAA RS01220
gene id: 1458425:SRAA_RS01220
uniprot id: A0A060NGM0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS06915
gene id: 1458425:SRAA_RS06915
uniprot id: A0A060NJD5
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

1458425:SRAA RS05550
gene id: 1458425:SRAA_RS05550
uniprot id: A0A060NPX4
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1458425:SRAA RS10210
gene id: 1458425:SRAA_RS10210
uniprot id: A0A060NIJ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS03740
gene id: 1458425:SRAA_RS03740
uniprot id: A0A060NG38
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1458425:SRAA RS02275
gene id: 1458425:SRAA_RS02275
uniprot id: A0A060NLE6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1458425:SRAA RS03685
gene id: 1458425:SRAA_RS03685
uniprot id: A0A060NG32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1458425:SRAA RS05455
gene id: 1458425:SRAA_RS05455
uniprot id: A0A060NGQ7
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1458425:SRAA RS08020
gene id: 1458425:SRAA_RS08020
uniprot id: A0A060NHP4
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1458425:SRAA RS00200
gene id: 1458425:SRAA_RS00200
uniprot id: A0A060NH01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1458425:SRAA RS01000
gene id: 1458425:SRAA_RS01000
uniprot id: A0A060NFA8
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1458425:SRAA RS08515
gene id: 1458425:SRAA_RS08515
uniprot id: A0A060NHU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1458425:SRAA RS05855
gene id: 1458425:SRAA_RS05855
uniprot id: A0A060NNA6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1458425:SRAA RS06390
gene id: 1458425:SRAA_RS06390
uniprot id: A0A060NH00
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family.
messages: Part of the 50S ribosomal subunit.

1458425:SRAA RS04600
gene id: 1458425:SRAA_RS04600
uniprot id: A0A060NIL7
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1458425:SRAA RS08630
gene id: 1458425:SRAA_RS08630
uniprot id: A0A060NRP3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1458425:SRAA RS00515
gene id: 1458425:SRAA_RS00515
uniprot id: A0A060NKJ0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1458425:SRAA RS08480
gene id: 1458425:SRAA_RS08480
uniprot id: A0A060NRK8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS00090
gene id: 1458425:SRAA_RS00090
uniprot id: A0A060NG94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1458425:SRAA RS07570
gene id: 1458425:SRAA_RS07570
uniprot id: A0A060NPE6
names: Similarity
messages: Belongs to the RecJ family.

1458425:SRAA RS09770
gene id: 1458425:SRAA_RS09770
uniprot id: A0A060NKH2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1458425:SRAA RS01890
gene id: 1458425:SRAA_RS01890
uniprot id: A0A060NFK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane

1458425:SRAA RS05965
gene id: 1458425:SRAA_RS05965
uniprot id: A0A060NJ19
names: Similarity
messages: Belongs to the peptidase S66 family.

1458425:SRAA RS08415
gene id: 1458425:SRAA_RS08415
uniprot id: A0A060NJW6
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

1458425:SRAA RS06295
gene id: 1458425:SRAA_RS06295
uniprot id: A0A060NIF6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1458425:SRAA RS10895
gene id: 1458425:SRAA_RS10895
uniprot id: A0A060NR49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1458425:SRAA RS11285
gene id: 1458425:SRAA_RS11285
uniprot id: A0A060NK83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1458425:SRAA RS00190
gene id: 1458425:SRAA_RS00190
uniprot id: A0A060NKE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1458425:SRAA RS10580
gene id: 1458425:SRAA_RS10580
uniprot id: A0A060NKU8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1458425:SRAA RS01290
gene id: 1458425:SRAA_RS01290
uniprot id: A0A060NFD1
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

1458425:SRAA RS08610
gene id: 1458425:SRAA_RS08610
uniprot id: A0A060NJZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1458425:SRAA RS07960
gene id: 1458425:SRAA_RS07960
uniprot id: A0A060NRB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1458425:SRAA RS00970
gene id: 1458425:SRAA_RS00970
uniprot id: A0A060NH84
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1458425:SRAA RS04940
gene id: 1458425:SRAA_RS04940
uniprot id: A0A060NI11
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1458425:SRAA RS07930
gene id: 1458425:SRAA_RS07930
uniprot id: A0A060NRB5
names: Similarity
messages: Belongs to the P(II) protein family.

1458425:SRAA RS10160
gene id: 1458425:SRAA_RS10160
uniprot id: A0A060NKQ0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1458425:SRAA RS03965
gene id: 1458425:SRAA_RS03965
uniprot id: A0A060NIB9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1458425:SRAA RS00150
gene id: 1458425:SRAA_RS00150
uniprot id: A0A060NGZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1458425:SRAA RS09750
gene id: 1458425:SRAA_RS09750
uniprot id: A0A060NIC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1458425:SRAA RS05065
gene id: 1458425:SRAA_RS05065
uniprot id: A0A060NIT5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1458425:SRAA RS07190
gene id: 1458425:SRAA_RS07190
uniprot id: A0A060NJH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1458425:SRAA RS02700
gene id: 1458425:SRAA_RS02700
uniprot id: A0A060NLM6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1458425:SRAA RS08380
gene id: 1458425:SRAA_RS08380
uniprot id: A0A060NPR6
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1458425:SRAA RS08035
gene id: 1458425:SRAA_RS08035
uniprot id: A0A060NRD2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1458425:SRAA RS02780
gene id: 1458425:SRAA_RS02780
uniprot id: A0A060NLN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1458425:SRAA RS04660
gene id: 1458425:SRAA_RS04660
uniprot id: A0A060NHV6
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS00990
gene id: 1458425:SRAA_RS00990
uniprot id: A0A060NMA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1458425:SRAA RS04950
gene id: 1458425:SRAA_RS04950
uniprot id: A0A060NPN7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1458425:SRAA RS03945
gene id: 1458425:SRAA_RS03945
uniprot id: A0A060NG55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

1458425:SRAA RS09155
gene id: 1458425:SRAA_RS09155
uniprot id: A0A060NQ74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1458425:SRAA RS11070
gene id: 1458425:SRAA_RS11070
uniprot id: A0A060NT26
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1458425:SRAA RS04440
gene id: 1458425:SRAA_RS04440
uniprot id: A0A060NHS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1458425:SRAA RS00125
gene id: 1458425:SRAA_RS00125
uniprot id: A0A060NLV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1458425:SRAA RS06190
gene id: 1458425:SRAA_RS06190
uniprot id: A0A060NIE4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS08795
gene id: 1458425:SRAA_RS08795
uniprot id: A0A060NHX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1458425:SRAA RS01500
gene id: 1458425:SRAA_RS01500
uniprot id: A0A060NKZ5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1458425:SRAA RS09210
gene id: 1458425:SRAA_RS09210
uniprot id: A0A060NS09
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1458425:SRAA RS11075
gene id: 1458425:SRAA_RS11075
uniprot id: A0A060NL22
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1458425:SRAA RS08540
gene id: 1458425:SRAA_RS08540
uniprot id: A0A060NHU8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS02255
gene id: 1458425:SRAA_RS02255
uniprot id: A0A060NN31
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1458425:SRAA RS01490
gene id: 1458425:SRAA_RS01490
uniprot id: A0A060NFE8
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1458425:SRAA RS09240
gene id: 1458425:SRAA_RS09240
uniprot id: A0A060NK78
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1458425:SRAA RS09800
gene id: 1458425:SRAA_RS09800
uniprot id: A0A060NIC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1458425:SRAA RS00615
gene id: 1458425:SRAA_RS00615
uniprot id: A0A060NKK2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1458425:SRAA RS07580
gene id: 1458425:SRAA_RS07580
uniprot id: A0A060NJN2
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1458425:SRAA RS09115
gene id: 1458425:SRAA_RS09115
uniprot id: A0A060NK59
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1458425:SRAA RS00110
gene id: 1458425:SRAA_RS00110
uniprot id: A0A060NF34
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS08460
gene id: 1458425:SRAA_RS08460
uniprot id: A0A060NRK3
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1458425:SRAA RS00535
gene id: 1458425:SRAA_RS00535
uniprot id: A0A060NGD9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS02220
gene id: 1458425:SRAA_RS02220
uniprot id: A0A060NH06
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1458425:SRAA RS07940
gene id: 1458425:SRAA_RS07940
uniprot id: A0A060NHN7
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS05920
gene id: 1458425:SRAA_RS05920
uniprot id: A0A060NGV0
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

1458425:SRAA RS06080
gene id: 1458425:SRAA_RS06080
uniprot id: A0A060NJ35
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS10095
gene id: 1458425:SRAA_RS10095
uniprot id: A0A060NJU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1458425:SRAA RS03585
gene id: 1458425:SRAA_RS03585
uniprot id: A0A060NG25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1458425:SRAA RS07075
gene id: 1458425:SRAA_RS07075
uniprot id: A0A060NIR4
names: Similarity
messages: Belongs to the GcvT family.

1458425:SRAA RS08910
gene id: 1458425:SRAA_RS08910
uniprot id: A0A060NRU7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1458425:SRAA RS05150
gene id: 1458425:SRAA_RS05150
uniprot id: A0A060NI30
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1458425:SRAA RS00310
gene id: 1458425:SRAA_RS00310
uniprot id: A0A060NF48
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1458425:SRAA RS06910
gene id: 1458425:SRAA_RS06910
uniprot id: A0A060NQP3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

1458425:SRAA RS06085
gene id: 1458425:SRAA_RS06085
uniprot id: A0A060NGW5
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS02370
gene id: 1458425:SRAA_RS02370
uniprot id: A0A060NH39
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1458425:SRAA RS06150
gene id: 1458425:SRAA_RS06150
uniprot id: A0A060NQ87
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1458425:SRAA RS00385
gene id: 1458425:SRAA_RS00385
uniprot id: A0A060NGC5
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1458425:SRAA RS04315
gene id: 1458425:SRAA_RS04315
uniprot id: A0A060NP67
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1458425:SRAA RS09185
gene id: 1458425:SRAA_RS09185
uniprot id: A0A060NS04
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1458425:SRAA RS08095
gene id: 1458425:SRAA_RS08095
uniprot id: A0A060NHQ0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1458425:SRAA RS07720
gene id: 1458425:SRAA_RS07720
uniprot id: A0A060NJ08
names: Similarity
messages: Belongs to the pirin family.

1458425:SRAA RS08755
gene id: 1458425:SRAA_RS08755
uniprot id: A0A060NPZ1
names: Subcellular Location Annotation
messages: Mitochondrion

1458425:SRAA RS11600
gene id: 1458425:SRAA_RS11600
uniprot id: A0A060NTC8
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1458425:SRAA RS08450
gene id: 1458425:SRAA_RS08450
uniprot id: A0A060NJ79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1458425:SRAA RS02920
gene id: 1458425:SRAA_RS02920
uniprot id: A0A060NH99
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1458425:SRAA RS08440
gene id: 1458425:SRAA_RS08440
uniprot id: A0A060NJX0
names: Cofactor
names: Subunit
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1458425:SRAA RS09280
gene id: 1458425:SRAA_RS09280
uniprot id: A0A060NQA4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1458425:SRAA RS02525
gene id: 1458425:SRAA_RS02525
uniprot id: A0A060NLK1
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS00165
gene id: 1458425:SRAA_RS00165
uniprot id: A0A060NKE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1458425:SRAA RS10485
gene id: 1458425:SRAA_RS10485
uniprot id: A0A060NIM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RfaH family.
messages: Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components.
messages: Interacts with both the nontemplate DNA and the RNA polymerase (RNAP).

1458425:SRAA RS01320
gene id: 1458425:SRAA_RS01320
uniprot id: A0A060NGN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane
messages: Homododecamer. Tetramer of trimer.
messages: Required for type IV pilus biogenesis and competence. Could function as a pore for exit of the pilus but also as a channel for entry of heme and antimicrobial agents and uptake of transforming DNA.

1458425:SRAA RS00635
gene id: 1458425:SRAA_RS00635
uniprot id: A0A060NGE9
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1458425:SRAA RS08330
gene id: 1458425:SRAA_RS08330
uniprot id: A0A060NJ65
names: Similarity
messages: Belongs to the DNA photolyase family.

1458425:SRAA RS10100
gene id: 1458425:SRAA_RS10100
uniprot id: A0A060NQT9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1458425:SRAA RS06280
gene id: 1458425:SRAA_RS06280
uniprot id: A0A060NQB2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1458425:SRAA RS04625
gene id: 1458425:SRAA_RS04625
uniprot id: A0A060NIM0
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1458425:SRAA RS03040
gene id: 1458425:SRAA_RS03040
uniprot id: A0A060NHB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1458425:SRAA RS00625
gene id: 1458425:SRAA_RS00625
uniprot id: A0A060NH35
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1458425:SRAA RS04550
gene id: 1458425:SRAA_RS04550
uniprot id: A0A060NIK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1458425:SRAA RS00740
gene id: 1458425:SRAA_RS00740
uniprot id: A0A060NF84
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS02605
gene id: 1458425:SRAA_RS02605
uniprot id: A0A060NHW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1458425:SRAA RS04910
gene id: 1458425:SRAA_RS04910
uniprot id: A0A060NGK2
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1458425:SRAA RS04210
gene id: 1458425:SRAA_RS04210
uniprot id: A0A060NHQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1458425:SRAA RS11170
gene id: 1458425:SRAA_RS11170
uniprot id: A0A060NT44
names: Similarity
messages: Belongs to the thioredoxin family.

1458425:SRAA RS03250
gene id: 1458425:SRAA_RS03250
uniprot id: A0A060NNL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1458425:SRAA RS08555
gene id: 1458425:SRAA_RS08555
uniprot id: A0A060NRM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1458425:SRAA RS07965
gene id: 1458425:SRAA_RS07965
uniprot id: A0A060NJR3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1458425:SRAA RS02795
gene id: 1458425:SRAA_RS02795
uniprot id: A0A060NFW5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1458425:SRAA RS06385
gene id: 1458425:SRAA_RS06385
uniprot id: A0A060NJ72
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS01790
gene id: 1458425:SRAA_RS01790
uniprot id: A0A060NGU8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1458425:SRAA RS09375
gene id: 1458425:SRAA_RS09375
uniprot id: A0A060NJI7
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1458425:SRAA RS05760
gene id: 1458425:SRAA_RS05760
uniprot id: A0A060NIZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1458425:SRAA RS10130
gene id: 1458425:SRAA_RS10130
uniprot id: A0A060NSM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1458425:SRAA RS03670
gene id: 1458425:SRAA_RS03670
uniprot id: A0A060NM37
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS11630
gene id: 1458425:SRAA_RS11630
uniprot id: A0A060NLC1
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO small chain family.
messages: Heterohexadecamer of 8 large and 8 small subunits.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

1458425:SRAA RS04585
gene id: 1458425:SRAA_RS04585
uniprot id: A0A060NHU4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1458425:SRAA RS11690
gene id: 1458425:SRAA_RS11690
uniprot id: A0A060NKE9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

1458425:SRAA RS06575
gene id: 1458425:SRAA_RS06575
uniprot id: A0A060NIJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

1458425:SRAA RS09645
gene id: 1458425:SRAA_RS09645
uniprot id: A0A060NKE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1458425:SRAA RS04785
gene id: 1458425:SRAA_RS04785
uniprot id: A0A060NHX5
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1458425:SRAA RS09025
gene id: 1458425:SRAA_RS09025
uniprot id: A0A060NJD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1458425:SRAA RS11425
gene id: 1458425:SRAA_RS11425
uniprot id: A0A060NL81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1458425:SRAA RS03675
gene id: 1458425:SRAA_RS03675
uniprot id: A0A060NNU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1458425:SRAA RS02035
gene id: 1458425:SRAA_RS02035
uniprot id: A0A060NHP0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1458425:SRAA RS07480
gene id: 1458425:SRAA_RS07480
uniprot id: A0A060NHJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1458425:SRAA RS06770
gene id: 1458425:SRAA_RS06770
uniprot id: A0A060NJB8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1458425:SRAA RS07915
gene id: 1458425:SRAA_RS07915
uniprot id: A0A060NHN4
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS00085
gene id: 1458425:SRAA_RS00085
uniprot id: A0A060NF31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1458425:SRAA RS02380
gene id: 1458425:SRAA_RS02380
uniprot id: A0A060NN82
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

1458425:SRAA RS10370
gene id: 1458425:SRAA_RS10370
uniprot id: A0A060NQX3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1458425:SRAA RS02105
gene id: 1458425:SRAA_RS02105
uniprot id: A0A060NMZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

1458425:SRAA RS09110
gene id: 1458425:SRAA_RS09110
uniprot id: A0A060NRY9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS08790
gene id: 1458425:SRAA_RS08790
uniprot id: A0A060NK15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1458425:SRAA RS07400
gene id: 1458425:SRAA_RS07400
uniprot id: A0A060NJL5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS08260
gene id: 1458425:SRAA_RS08260
uniprot id: A0A060NPP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1458425:SRAA RS03850
gene id: 1458425:SRAA_RS03850
uniprot id: A0A060NM72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1458425:SRAA RS09735
gene id: 1458425:SRAA_RS09735
uniprot id: A0A060NQK3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1458425:SRAA RS07535
gene id: 1458425:SRAA_RS07535
uniprot id: A0A060NHJ8
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1458425:SRAA RS02470
gene id: 1458425:SRAA_RS02470
uniprot id: A0A060NH50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1458425:SRAA RS09755
gene id: 1458425:SRAA_RS09755
uniprot id: A0A060NJN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1458425:SRAA RS04740
gene id: 1458425:SRAA_RS04740
uniprot id: A0A060NMR2
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1458425:SRAA RS06470
gene id: 1458425:SRAA_RS06470
uniprot id: A0A060NIH8
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS05695
gene id: 1458425:SRAA_RS05695
uniprot id: A0A060NI80
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1458425:SRAA RS02910
gene id: 1458425:SRAA_RS02910
uniprot id: A0A060NNF7
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1458425:SRAA RS01520
gene id: 1458425:SRAA_RS01520
uniprot id: A0A060NGR2
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1458425:SRAA RS02995
gene id: 1458425:SRAA_RS02995
uniprot id: A0A060NLR2
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1458425:SRAA RS00055
gene id: 1458425:SRAA_RS00055
uniprot id: A0A060NGY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1458425:SRAA RS11660
gene id: 1458425:SRAA_RS11660
uniprot id: A0A060NIZ7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS03540
gene id: 1458425:SRAA_RS03540
uniprot id: A0A060NHH3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

1458425:SRAA RS08865
gene id: 1458425:SRAA_RS08865
uniprot id: A0A060NK25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1458425:SRAA RS05300
gene id: 1458425:SRAA_RS05300
uniprot id: A0A060NGP2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1458425:SRAA RS01515
gene id: 1458425:SRAA_RS01515
uniprot id: A0A060NFF1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1458425:SRAA RS10040
gene id: 1458425:SRAA_RS10040
uniprot id: A0A060NII0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS07770
gene id: 1458425:SRAA_RS07770
uniprot id: A0A060NJ11
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1458425:SRAA RS01280
gene id: 1458425:SRAA_RS01280
uniprot id: A0A060NMG9
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS03425
gene id: 1458425:SRAA_RS03425
uniprot id: A0A060NI46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1458425:SRAA RS06620
gene id: 1458425:SRAA_RS06620
uniprot id: A0A060NIK2
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1458425:SRAA RS09990
gene id: 1458425:SRAA_RS09990
uniprot id: A0A060NIH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1458425:SRAA RS10800
gene id: 1458425:SRAA_RS10800
uniprot id: A0A060NSX2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1458425:SRAA RS11000
gene id: 1458425:SRAA_RS11000
uniprot id: A0A060NL09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

1458425:SRAA RS09410
gene id: 1458425:SRAA_RS09410
uniprot id: A0A060NS45
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1458425:SRAA RS03925
gene id: 1458425:SRAA_RS03925
uniprot id: A0A060NHL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1458425:SRAA RS08045
gene id: 1458425:SRAA_RS08045
uniprot id: A0A060NHP6
names: Caution
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1458425:SRAA RS00815
gene id: 1458425:SRAA_RS00815
uniprot id: A0A060NGG9
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

1458425:SRAA RS01405
gene id: 1458425:SRAA_RS01405
uniprot id: A0A060NMJ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1458425:SRAA RS04990
gene id: 1458425:SRAA_RS04990
uniprot id: A0A060NI16
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 104 family.
messages: Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes.

1458425:SRAA RS04420
gene id: 1458425:SRAA_RS04420
uniprot id: A0A060NMJ5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS04865
gene id: 1458425:SRAA_RS04865
uniprot id: A0A060NI03
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1458425:SRAA RS02215
gene id: 1458425:SRAA_RS02215
uniprot id: A0A060NFQ3
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1458425:SRAA RS05670
gene id: 1458425:SRAA_RS05670
uniprot id: A0A060NI79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1458425:SRAA RS09845
gene id: 1458425:SRAA_RS09845
uniprot id: A0A060NKI6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1458425:SRAA RS10010
gene id: 1458425:SRAA_RS10010
uniprot id: A0A060NKN3
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1458425:SRAA RS05480
gene id: 1458425:SRAA_RS05480
uniprot id: A0A060NGR1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1458425:SRAA RS03170
gene id: 1458425:SRAA_RS03170
uniprot id: A0A060NLU0
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1458425:SRAA RS03405
gene id: 1458425:SRAA_RS03405
uniprot id: A0A060NG13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1458425:SRAA RS10825
gene id: 1458425:SRAA_RS10825
uniprot id: A0A060NSX7
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1458425:SRAA RS04980
gene id: 1458425:SRAA_RS04980
uniprot id: A0A060NIS9
names: Similarity
messages: Belongs to the LOG family.

1458425:SRAA RS06520
gene id: 1458425:SRAA_RS06520
uniprot id: A0A060NH17
names: Similarity
messages: Belongs to the CcdB toxin family.

1458425:SRAA RS07795
gene id: 1458425:SRAA_RS07795
uniprot id: A0A060NJ14
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1458425:SRAA RS07000
gene id: 1458425:SRAA_RS07000
uniprot id: A0A060NHA2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

1458425:SRAA RS06570
gene id: 1458425:SRAA_RS06570
uniprot id: A0A060NH22
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS10660
gene id: 1458425:SRAA_RS10660
uniprot id: A0A060NIN7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1458425:SRAA RS10490
gene id: 1458425:SRAA_RS10490
uniprot id: A0A060NJZ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1458425:SRAA RS06260
gene id: 1458425:SRAA_RS06260
uniprot id: A0A060NJ57
names: Similarity
messages: Belongs to the aspartokinase family.

1458425:SRAA RS10625
gene id: 1458425:SRAA_RS10625
uniprot id: A0A060NSU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1458425:SRAA RS00160
gene id: 1458425:SRAA_RS00160
uniprot id: A0A060NGA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1458425:SRAA RS09710
gene id: 1458425:SRAA_RS09710
uniprot id: A0A060NJM8
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS08155
gene id: 1458425:SRAA_RS08155
uniprot id: A0A060NJ48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1458425:SRAA RS05850
gene id: 1458425:SRAA_RS05850
uniprot id: A0A060NI98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1458425:SRAA RS04430
gene id: 1458425:SRAA_RS04430
uniprot id: A0A060NII7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1458425:SRAA RS07890
gene id: 1458425:SRAA_RS07890
uniprot id: A0A060NHN2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1458425:SRAA RS03070
gene id: 1458425:SRAA_RS03070
uniprot id: A0A060NLS3
names: Similarity
messages: Belongs to the GSP E family.

1458425:SRAA RS08060
gene id: 1458425:SRAA_RS08060
uniprot id: A0A060NRD7
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1458425:SRAA RS08090
gene id: 1458425:SRAA_RS08090
uniprot id: A0A060NJS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1458425:SRAA RS10785
gene id: 1458425:SRAA_RS10785
uniprot id: A0A060NIP9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1458425:SRAA RS03505
gene id: 1458425:SRAA_RS03505
uniprot id: A0A060NG20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1458425:SRAA RS10030
gene id: 1458425:SRAA_RS10030
uniprot id: A0A060NSK9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1458425:SRAA RS06550
gene id: 1458425:SRAA_RS06550
uniprot id: A0A060NIJ1
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1458425:SRAA RS09530
gene id: 1458425:SRAA_RS09530
uniprot id: A0A060NJK4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1458425:SRAA RS05780
gene id: 1458425:SRAA_RS05780
uniprot id: A0A060NN91
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS04630
gene id: 1458425:SRAA_RS04630
uniprot id: A0A060NGD6
names: Similarity
messages: Belongs to the GST superfamily.

1458425:SRAA RS01800
gene id: 1458425:SRAA_RS01800
uniprot id: A0A060NMS7
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

1458425:SRAA RS06855
gene id: 1458425:SRAA_RS06855
uniprot id: A0A060NIN8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1458425:SRAA RS06935
gene id: 1458425:SRAA_RS06935
uniprot id: A0A060NQQ0
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1458425:SRAA RS05680
gene id: 1458425:SRAA_RS05680
uniprot id: A0A060NPZ4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1458425:SRAA RS08725
gene id: 1458425:SRAA_RS08725
uniprot id: A0A060NJA8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS11650
gene id: 1458425:SRAA_RS11650
uniprot id: A0A060NTD9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1458425:SRAA RS03190
gene id: 1458425:SRAA_RS03190
uniprot id: A0A060NHD1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1458425:SRAA RS08690
gene id: 1458425:SRAA_RS08690
uniprot id: A0A060NHW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1458425:SRAA RS06465
gene id: 1458425:SRAA_RS06465
uniprot id: A0A060NH11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1458425:SRAA RS10640
gene id: 1458425:SRAA_RS10640
uniprot id: A0A060NK06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1458425:SRAA RS07470
gene id: 1458425:SRAA_RS07470
uniprot id: A0A060NR47
names: Similarity
messages: Belongs to the UPF0234 family.

1458425:SRAA RS09540
gene id: 1458425:SRAA_RS09540
uniprot id: A0A060NS77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1458425:SRAA RS00600
gene id: 1458425:SRAA_RS00600
uniprot id: A0A060NH32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1458425:SRAA RS01235
gene id: 1458425:SRAA_RS01235
uniprot id: A0A060NHC3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1458425:SRAA RS08370
gene id: 1458425:SRAA_RS08370
uniprot id: A0A060NHT1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1458425:SRAA RS07225
gene id: 1458425:SRAA_RS07225
uniprot id: A0A060NIT7
names: Similarity
messages: Belongs to the DprA/Smf family.

1458425:SRAA RS05640
gene id: 1458425:SRAA_RS05640
uniprot id: A0A060NGS6
names: Similarity
messages: Belongs to the peptidase M16 family.

1458425:SRAA RS08320
gene id: 1458425:SRAA_RS08320
uniprot id: A0A060NJV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1458425:SRAA RS05860
gene id: 1458425:SRAA_RS05860
uniprot id: A0A060NQ23
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1458425:SRAA RS03755
gene id: 1458425:SRAA_RS03755
uniprot id: A0A060NNV7
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS07110
gene id: 1458425:SRAA_RS07110
uniprot id: A0A060NQU4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1458425:SRAA RS04765
gene id: 1458425:SRAA_RS04765
uniprot id: A0A060NMS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1458425:SRAA RS03120
gene id: 1458425:SRAA_RS03120
uniprot id: A0A060NLT2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1458425:SRAA RS10560
gene id: 1458425:SRAA_RS10560
uniprot id: A0A060NIM7
names: PTM
messages: Binds 1 heme group per subunit.

1458425:SRAA RS10025
gene id: 1458425:SRAA_RS10025
uniprot id: A0A060NQS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1458425:SRAA RS08070
gene id: 1458425:SRAA_RS08070
uniprot id: A0A060NHP8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1458425:SRAA RS00145
gene id: 1458425:SRAA_RS00145
uniprot id: A0A060NLV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1458425:SRAA RS11680
gene id: 1458425:SRAA_RS11680
uniprot id: A0A060NLC9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1458425:SRAA RS10035
gene id: 1458425:SRAA_RS10035
uniprot id: A0A060NKN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1458425:SRAA RS09455
gene id: 1458425:SRAA_RS09455
uniprot id: A0A060NJJ7
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS01980
gene id: 1458425:SRAA_RS01980
uniprot id: A0A060NMV8
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1458425:SRAA RS02120
gene id: 1458425:SRAA_RS02120
uniprot id: A0A060NGY8
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1458425:SRAA RS04970
gene id: 1458425:SRAA_RS04970
uniprot id: A0A060NMX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1458425:SRAA RS08310
gene id: 1458425:SRAA_RS08310
uniprot id: A0A060NPQ3
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.

1458425:SRAA RS00250
gene id: 1458425:SRAA_RS00250
uniprot id: A0A060NLX8
names: Function
names: Similarity
messages: Belongs to the UbiT family.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor.

1458425:SRAA RS05955
gene id: 1458425:SRAA_RS05955
uniprot id: A0A060NNC3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1458425:SRAA RS05560
gene id: 1458425:SRAA_RS05560
uniprot id: A0A060NGR9
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1458425:SRAA RS06645
gene id: 1458425:SRAA_RS06645
uniprot id: A0A060NIK5
names: Similarity
messages: Belongs to the ModE family.

1458425:SRAA RS04775
gene id: 1458425:SRAA_RS04775
uniprot id: A0A060NIP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1458425:SRAA RS07195
gene id: 1458425:SRAA_RS07195
uniprot id: A0A060NHE0
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1458425:SRAA RS01270
gene id: 1458425:SRAA_RS01270
uniprot id: A0A060NGM8
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1458425:SRAA RS02425
gene id: 1458425:SRAA_RS02425
uniprot id: A0A060NLI9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1458425:SRAA RS08885
gene id: 1458425:SRAA_RS08885
uniprot id: A0A060NRU3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1458425:SRAA RS11185
gene id: 1458425:SRAA_RS11185
uniprot id: A0A060NK69
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1458425:SRAA RS04560
gene id: 1458425:SRAA_RS04560
uniprot id: A0A060NHU0
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1458425:SRAA RS03990
gene id: 1458425:SRAA_RS03990
uniprot id: A0A060NIC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

1458425:SRAA RS07740
gene id: 1458425:SRAA_RS07740
uniprot id: A0A060NHL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1458425:SRAA RS07550
gene id: 1458425:SRAA_RS07550
uniprot id: A0A060NR55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

1458425:SRAA RS05715
gene id: 1458425:SRAA_RS05715
uniprot id: A0A060NGT3
names: Similarity
messages: Belongs to the peptidase A31 family.

1458425:SRAA RS01065
gene id: 1458425:SRAA_RS01065
uniprot id: A0A060NH98
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1458425:SRAA RS05360
gene id: 1458425:SRAA_RS05360
uniprot id: A0A060NPU3
names: Similarity
messages: Belongs to the cytochrome P450 family.

1458425:SRAA RS10410
gene id: 1458425:SRAA_RS10410
uniprot id: A0A060NIL4
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1458425:SRAA RS06830
gene id: 1458425:SRAA_RS06830
uniprot id: A0A060NIN5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1458425:SRAA RS07910
gene id: 1458425:SRAA_RS07910
uniprot id: A0A060NJQ9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1458425:SRAA RS11640
gene id: 1458425:SRAA_RS11640
uniprot id: A0A060NKE0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1458425:SRAA RS10435
gene id: 1458425:SRAA_RS10435
uniprot id: A0A060NIL6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1458425:SRAA RS06630
gene id: 1458425:SRAA_RS06630
uniprot id: A0A060NQI5
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1458425:SRAA RS09685
gene id: 1458425:SRAA_RS09685
uniprot id: A0A060NJM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1458425:SRAA RS09180
gene id: 1458425:SRAA_RS09180
uniprot id: A0A060NQ81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1458425:SRAA RS11045
gene id: 1458425:SRAA_RS11045
uniprot id: A0A060NT20
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS04780
gene id: 1458425:SRAA_RS04780
uniprot id: A0A060NGG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1458425:SRAA RS10020
gene id: 1458425:SRAA_RS10020
uniprot id: A0A060NJT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1458425:SRAA RS06590
gene id: 1458425:SRAA_RS06590
uniprot id: A0A060NJ95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

1458425:SRAA RS00195
gene id: 1458425:SRAA_RS00195
uniprot id: A0A060NLW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1458425:SRAA RS07135
gene id: 1458425:SRAA_RS07135
uniprot id: A0A060NQV0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS10115
gene id: 1458425:SRAA_RS10115
uniprot id: A0A060NII8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1458425:SRAA RS06220
gene id: 1458425:SRAA_RS06220
uniprot id: A0A060NNI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1458425:SRAA RS03890
gene id: 1458425:SRAA_RS03890
uniprot id: A0A060NG51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1458425:SRAA RS06780
gene id: 1458425:SRAA_RS06780
uniprot id: A0A060NIM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1458425:SRAA RS07900
gene id: 1458425:SRAA_RS07900
uniprot id: A0A060NPJ4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS04110
gene id: 1458425:SRAA_RS04110
uniprot id: A0A060NHP2
names: Similarity
messages: Belongs to the TPP enzyme family.

1458425:SRAA RS11935
gene id: 1458425:SRAA_RS11935
uniprot id: A0A060NLF6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS05435
gene id: 1458425:SRAA_RS05435
uniprot id: A0A060NPV6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1458425:SRAA RS01140
gene id: 1458425:SRAA_RS01140
uniprot id: A0A060NFC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1458425:SRAA RS06065
gene id: 1458425:SRAA_RS06065
uniprot id: A0A060NIC7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1458425:SRAA RS08675
gene id: 1458425:SRAA_RS08675
uniprot id: A0A060NPX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1458425:SRAA RS10635
gene id: 1458425:SRAA_RS10635
uniprot id: A0A060NIN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1458425:SRAA RS06880
gene id: 1458425:SRAA_RS06880
uniprot id: A0A060NIP1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1458425:SRAA RS05410
gene id: 1458425:SRAA_RS05410
uniprot id: A0A060NPV2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1458425:SRAA RS00285
gene id: 1458425:SRAA_RS00285
uniprot id: A0A060NF47
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1458425:SRAA RS10585
gene id: 1458425:SRAA_RS10585
uniprot id: A0A060NIN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1458425:SRAA RS08160
gene id: 1458425:SRAA_RS08160
uniprot id: A0A060NPM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1458425:SRAA RS10890
gene id: 1458425:SRAA_RS10890
uniprot id: A0A060NK33
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1458425:SRAA RS06120
gene id: 1458425:SRAA_RS06120
uniprot id: A0A060NNG1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1458425:SRAA RS00520
gene id: 1458425:SRAA_RS00520
uniprot id: A0A060NM23
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1458425:SRAA RS11065
gene id: 1458425:SRAA_RS11065
uniprot id: A0A060NR77
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

1458425:SRAA RS03745
gene id: 1458425:SRAA_RS03745
uniprot id: A0A060NHJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1458425:SRAA RS03730
gene id: 1458425:SRAA_RS03730
uniprot id: A0A060NNV2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1458425:SRAA RS02365
gene id: 1458425:SRAA_RS02365
uniprot id: A0A060NFT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1458425:SRAA RS04225
gene id: 1458425:SRAA_RS04225
uniprot id: A0A060NIF5
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1458425:SRAA RS03375
gene id: 1458425:SRAA_RS03375
uniprot id: A0A060NI39
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1458425:SRAA RS08615
gene id: 1458425:SRAA_RS08615
uniprot id: A0A060NHV7
names: Similarity
messages: Belongs to the fabD family.

1458425:SRAA RS09970
gene id: 1458425:SRAA_RS09970
uniprot id: A0A060NJT1
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1458425:SRAA RS09085
gene id: 1458425:SRAA_RS09085
uniprot id: A0A060NRY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1458425:SRAA RS00885
gene id: 1458425:SRAA_RS00885
uniprot id: A0A060NF96
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS02450
gene id: 1458425:SRAA_RS02450
uniprot id: A0A060NLJ1
names: Subcellular Location Annotation
messages: Secreted

1458425:SRAA RS02890
gene id: 1458425:SRAA_RS02890
uniprot id: A0A060NHZ0
names: Subunit
messages: Homodimer.

1458425:SRAA RS10795
gene id: 1458425:SRAA_RS10795
uniprot id: A0A060NR34
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1458425:SRAA RS11250
gene id: 1458425:SRAA_RS11250
uniprot id: A0A060NL50
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1458425:SRAA RS01240
gene id: 1458425:SRAA_RS01240
uniprot id: A0A060NFC8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1458425:SRAA RS02745
gene id: 1458425:SRAA_RS02745
uniprot id: A0A060NLN2
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1458425:SRAA RS10070
gene id: 1458425:SRAA_RS10070
uniprot id: A0A060NJU3
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

1458425:SRAA RS04370
gene id: 1458425:SRAA_RS04370
uniprot id: A0A060NP75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1458425:SRAA RS00175
gene id: 1458425:SRAA_RS00175
uniprot id: A0A060NGZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1458425:SRAA RS03780
gene id: 1458425:SRAA_RS03780
uniprot id: A0A060NNW2
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1458425:SRAA RS08225
gene id: 1458425:SRAA_RS08225
uniprot id: A0A060NHR9
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1458425:SRAA RS04460
gene id: 1458425:SRAA_RS04460
uniprot id: A0A060NGA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS01805
gene id: 1458425:SRAA_RS01805
uniprot id: A0A060NHK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1458425:SRAA RS05615
gene id: 1458425:SRAA_RS05615
uniprot id: A0A060NGS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1458425:SRAA RS11670
gene id: 1458425:SRAA_RS11670
uniprot id: A0A060NRK5
names: Similarity
messages: Belongs to the transketolase family.

1458425:SRAA RS02110
gene id: 1458425:SRAA_RS02110
uniprot id: A0A060NHQ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1458425:SRAA RS01175
gene id: 1458425:SRAA_RS01175
uniprot id: A0A060NKT9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1458425:SRAA RS00850
gene id: 1458425:SRAA_RS00850
uniprot id: A0A060NM78
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1458425:SRAA RS07610
gene id: 1458425:SRAA_RS07610
uniprot id: A0A060NHK5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1458425:SRAA RS02720
gene id: 1458425:SRAA_RS02720
uniprot id: A0A060NLM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

1458425:SRAA RS07615
gene id: 1458425:SRAA_RS07615
uniprot id: A0A060NIZ9
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1458425:SRAA RS09635
gene id: 1458425:SRAA_RS09635
uniprot id: A0A060NQI2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1458425:SRAA RS08655
gene id: 1458425:SRAA_RS08655
uniprot id: A0A060NRP8
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1458425:SRAA RS03940
gene id: 1458425:SRAA_RS03940
uniprot id: A0A060NIB4
names: Similarity
messages: Belongs to the GARS family.

1458425:SRAA RS03550
gene id: 1458425:SRAA_RS03550
uniprot id: A0A060NNR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1458425:SRAA RS01095
gene id: 1458425:SRAA_RS01095
uniprot id: A0A060NFB6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

1458425:SRAA RS03720
gene id: 1458425:SRAA_RS03720
uniprot id: A0A060NHJ4
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1458425:SRAA RS10200
gene id: 1458425:SRAA_RS10200
uniprot id: A0A060NSM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1458425:SRAA RS00445
gene id: 1458425:SRAA_RS00445
uniprot id: A0A060NM10
names: Similarity
messages: Belongs to the GSP E family.

1458425:SRAA RS04800
gene id: 1458425:SRAA_RS04800
uniprot id: A0A060NIP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1458425:SRAA RS06365
gene id: 1458425:SRAA_RS06365
uniprot id: A0A060NGZ6
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1458425:SRAA RS09005
gene id: 1458425:SRAA_RS09005
uniprot id: A0A060NQ39
names: Similarity
messages: Belongs to the CopC family.

1458425:SRAA RS06210
gene id: 1458425:SRAA_RS06210
uniprot id: A0A060NGX7
names: Similarity
messages: Belongs to the UPF0758 family.

1458425:SRAA RS06360
gene id: 1458425:SRAA_RS06360
uniprot id: A0A060NJ69
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1458425:SRAA RS06375
gene id: 1458425:SRAA_RS06375
uniprot id: A0A060NNL1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1458425:SRAA RS11165
gene id: 1458425:SRAA_RS11165
uniprot id: A0A060NR98
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1458425:SRAA RS08125
gene id: 1458425:SRAA_RS08125
uniprot id: A0A060NHQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1458425:SRAA RS00005
gene id: 1458425:SRAA_RS00005
uniprot id: A0A060NGY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1458425:SRAA RS06895
gene id: 1458425:SRAA_RS06895
uniprot id: A0A060NJD2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1458425:SRAA RS05375
gene id: 1458425:SRAA_RS05375
uniprot id: A0A060NI52
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

1458425:SRAA RS06905
gene id: 1458425:SRAA_RS06905
uniprot id: A0A060NNZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1458425:SRAA RS04145
gene id: 1458425:SRAA_RS04145
uniprot id: A0A060NP33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1458425:SRAA RS00380
gene id: 1458425:SRAA_RS00380
uniprot id: A0A060NF55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1458425:SRAA RS04900
gene id: 1458425:SRAA_RS04900
uniprot id: A0A060NPN1
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1458425:SRAA RS02770
gene id: 1458425:SRAA_RS02770
uniprot id: A0A060NFW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1458425:SRAA RS09610
gene id: 1458425:SRAA_RS09610
uniprot id: A0A060NQH6
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1458425:SRAA RS00095
gene id: 1458425:SRAA_RS00095
uniprot id: A0A060NKD6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1458425:SRAA RS11375
gene id: 1458425:SRAA_RS11375
uniprot id: A0A060NL72
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS06500
gene id: 1458425:SRAA_RS06500
uniprot id: A0A060NNN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1458425:SRAA RS11060
gene id: 1458425:SRAA_RS11060
uniprot id: A0A060NK54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1458425:SRAA RS06110
gene id: 1458425:SRAA_RS06110
uniprot id: A0A060NGW7
names: Similarity
messages: Belongs to the BolA/IbaG family.

1458425:SRAA RS02460
gene id: 1458425:SRAA_RS02460
uniprot id: A0A060NHV3
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

1458425:SRAA RS04190
gene id: 1458425:SRAA_RS04190
uniprot id: A0A060NME7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

1458425:SRAA RS00795
gene id: 1458425:SRAA_RS00795
uniprot id: A0A060NGG6
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

1458425:SRAA RS06695
gene id: 1458425:SRAA_RS06695
uniprot id: A0A060NIL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1458425:SRAA RS09100
gene id: 1458425:SRAA_RS09100
uniprot id: A0A060NJE8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1458425:SRAA RS01715
gene id: 1458425:SRAA_RS01715
uniprot id: A0A060NFI2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1458425:SRAA RS00075
gene id: 1458425:SRAA_RS00075
uniprot id: A0A060NLU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1458425:SRAA RS03130
gene id: 1458425:SRAA_RS03130
uniprot id: A0A060NI09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1458425:SRAA RS09835
gene id: 1458425:SRAA_RS09835
uniprot id: A0A060NQM4
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1458425:SRAA RS10715
gene id: 1458425:SRAA_RS10715
uniprot id: A0A060NK14
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1458425:SRAA RS03560
gene id: 1458425:SRAA_RS03560
uniprot id: A0A060NG23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1458425:SRAA RS05745
gene id: 1458425:SRAA_RS05745
uniprot id: A0A060NI86
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1458425:SRAA RS09420
gene id: 1458425:SRAA_RS09420
uniprot id: A0A060NI63
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1458425:SRAA RS01985
gene id: 1458425:SRAA_RS01985
uniprot id: A0A060NHN1
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1458425:SRAA RS03185
gene id: 1458425:SRAA_RS03185
uniprot id: A0A060NFZ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1458425:SRAA RS02970
gene id: 1458425:SRAA_RS02970
uniprot id: A0A060NFX6
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1458425:SRAA RS00580
gene id: 1458425:SRAA_RS00580
uniprot id: A0A060NF71
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1458425:SRAA RS10600
gene id: 1458425:SRAA_RS10600
uniprot id: A0A060NST9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1458425:SRAA RS10015
gene id: 1458425:SRAA_RS10015
uniprot id: A0A060NIH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1458425:SRAA RS11460
gene id: 1458425:SRAA_RS11460
uniprot id: A0A060NKA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates influx of magnesium ions.
messages: Membrane

1458425:SRAA RS10000
gene id: 1458425:SRAA_RS10000
uniprot id: A0A060NQS6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1458425:SRAA RS04770
gene id: 1458425:SRAA_RS04770
uniprot id: A0A060NPH3
names: Similarity
messages: Belongs to the UPF0434 family.

1458425:SRAA RS05280
gene id: 1458425:SRAA_RS05280
uniprot id: A0A060NI43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1458425:SRAA RS02160
gene id: 1458425:SRAA_RS02160
uniprot id: A0A060NHQ7
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

1458425:SRAA RS07925
gene id: 1458425:SRAA_RS07925
uniprot id: A0A060NPJ9
names: Similarity
messages: Belongs to the LOG family.

1458425:SRAA RS03545
gene id: 1458425:SRAA_RS03545
uniprot id: A0A060NM14
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1458425:SRAA RS09260
gene id: 1458425:SRAA_RS09260
uniprot id: A0A060NS17
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

1458425:SRAA RS02615
gene id: 1458425:SRAA_RS02615
uniprot id: A0A060NH64
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1458425:SRAA RS03910
gene id: 1458425:SRAA_RS03910
uniprot id: A0A060NIB0
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

1458425:SRAA RS04255
gene id: 1458425:SRAA_RS04255
uniprot id: A0A060NHR2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1458425:SRAA RS02020
gene id: 1458425:SRAA_RS02020
uniprot id: A0A060NGX2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1458425:SRAA RS10055
gene id: 1458425:SRAA_RS10055
uniprot id: A0A060NSL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1458425:SRAA RS07445
gene id: 1458425:SRAA_RS07445
uniprot id: A0A060NR44
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1458425:SRAA RS08545
gene id: 1458425:SRAA_RS08545
uniprot id: A0A060NJ88
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1458425:SRAA RS06060
gene id: 1458425:SRAA_RS06060
uniprot id: A0A060NGW3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1458425:SRAA RS00015
gene id: 1458425:SRAA_RS00015
uniprot id: A0A060NG90
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1458425:SRAA RS03735
gene id: 1458425:SRAA_RS03735
uniprot id: A0A060NI84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1458425:SRAA RS10475
gene id: 1458425:SRAA_RS10475
uniprot id: A0A060NSR9
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1458425:SRAA RS05025
gene id: 1458425:SRAA_RS05025
uniprot id: A0A060NPP7
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1458425:SRAA RS00290
gene id: 1458425:SRAA_RS00290
uniprot id: A0A060NGB5
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS09915
gene id: 1458425:SRAA_RS09915
uniprot id: A0A060NQR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1458425:SRAA RS06205
gene id: 1458425:SRAA_RS06205
uniprot id: A0A060NJ51
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1458425:SRAA RS09745
gene id: 1458425:SRAA_RS09745
uniprot id: A0A060NKG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

1458425:SRAA RS07430
gene id: 1458425:SRAA_RS07430
uniprot id: A0A060NHI8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1458425:SRAA RS11220
gene id: 1458425:SRAA_RS11220
uniprot id: A0A060NT53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1458425:SRAA RS08000
gene id: 1458425:SRAA_RS08000
uniprot id: A0A060NJ33
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1458425:SRAA RS06270
gene id: 1458425:SRAA_RS06270
uniprot id: A0A060NIF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1458425:SRAA RS05130
gene id: 1458425:SRAA_RS05130
uniprot id: A0A060NN00
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1458425:SRAA RS11825
gene id: 1458425:SRAA_RS11825
uniprot id: A0A060NLE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1458425:SRAA RS00605
gene id: 1458425:SRAA_RS00605
uniprot id: A0A060NF72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1458425:SRAA RS09840
gene id: 1458425:SRAA_RS09840
uniprot id: A0A060NSF6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters.

1458425:SRAA RS10700
gene id: 1458425:SRAA_RS10700
uniprot id: A0A060NSV6
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1458425:SRAA RS04925
gene id: 1458425:SRAA_RS04925
uniprot id: A0A060NPN5
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1458425:SRAA RS02775
gene id: 1458425:SRAA_RS02775
uniprot id: A0A060NH81
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1458425:SRAA RS04410
gene id: 1458425:SRAA_RS04410
uniprot id: A0A060NG98
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

1458425:SRAA RS04235
gene id: 1458425:SRAA_RS04235
uniprot id: A0A060NHQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1458425:SRAA RS03065
gene id: 1458425:SRAA_RS03065
uniprot id: A0A060NHB5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1458425:SRAA RS08485
gene id: 1458425:SRAA_RS08485
uniprot id: A0A060NJX7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

1458425:SRAA RS10225
gene id: 1458425:SRAA_RS10225
uniprot id: A0A060NSN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1458425:SRAA RS01755
gene id: 1458425:SRAA_RS01755
uniprot id: A0A060NMR6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1458425:SRAA RS03445
gene id: 1458425:SRAA_RS03445
uniprot id: A0A060NNP6
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1458425:SRAA RS07500
gene id: 1458425:SRAA_RS07500
uniprot id: A0A060NR51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1458425:SRAA RS04860
gene id: 1458425:SRAA_RS04860
uniprot id: A0A060NGI8
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1458425:SRAA RS00790
gene id: 1458425:SRAA_RS00790
uniprot id: A0A060NF88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-2 integral membrane protein family. Lipooligosaccharide exporter (TC 3.A.1.102) subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction. Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide. This subunit encodes the transporter.
messages: The complex is composed of two ATP-binding proteins (NodI) and two transmembrane proteins (NodJ).

1458425:SRAA RS02340
gene id: 1458425:SRAA_RS02340
uniprot id: A0A060NFT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1458425:SRAA RS03325
gene id: 1458425:SRAA_RS03325
uniprot id: A0A060NNM2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1458425:SRAA RS10240
gene id: 1458425:SRAA_RS10240
uniprot id: A0A060NJW0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1458425:SRAA RS11280
gene id: 1458425:SRAA_RS11280
uniprot id: A0A060NIU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1458425:SRAA RS02635
gene id: 1458425:SRAA_RS02635
uniprot id: A0A060NFV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1458425:SRAA RS06405
gene id: 1458425:SRAA_RS06405
uniprot id: A0A060NQE1
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1458425:SRAA RS10985
gene id: 1458425:SRAA_RS10985
uniprot id: A0A060NK44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1458425:SRAA RS07865
gene id: 1458425:SRAA_RS07865
uniprot id: A0A060NHN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS03495
gene id: 1458425:SRAA_RS03495
uniprot id: A0A060NNQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1458425:SRAA RS11665
gene id: 1458425:SRAA_RS11665
uniprot id: A0A060NKE4
names: Similarity
messages: Belongs to the phosphoribulokinase family.

1458425:SRAA RS02610
gene id: 1458425:SRAA_RS02610
uniprot id: A0A060NFV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1458425:SRAA RS02055
gene id: 1458425:SRAA_RS02055
uniprot id: A0A060NMX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1458425:SRAA RS08880
gene id: 1458425:SRAA_RS08880
uniprot id: A0A060NQ13
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1458425:SRAA RS08220
gene id: 1458425:SRAA_RS08220
uniprot id: A0A060NJT8
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1458425:SRAA RS04875
gene id: 1458425:SRAA_RS04875
uniprot id: A0A060NPM6
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

1458425:SRAA RS12025
gene id: 1458425:SRAA_RS12025
uniprot id: A0A060NI14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1458425:SRAA RS04650
gene id: 1458425:SRAA_RS04650
uniprot id: A0A060NIM4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

1458425:SRAA RS04520
gene id: 1458425:SRAA_RS04520
uniprot id: A0A060NPA6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

1458425:SRAA RS09235
gene id: 1458425:SRAA_RS09235
uniprot id: A0A060NS13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1458425:SRAA RS02535
gene id: 1458425:SRAA_RS02535
uniprot id: A0A060NHW0
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

1458425:SRAA RS08465
gene id: 1458425:SRAA_RS08465
uniprot id: A0A060NJX3
names: Similarity
messages: Belongs to the citrate synthase family.

1458425:SRAA RS01360
gene id: 1458425:SRAA_RS01360
uniprot id: A0A060NHE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

1458425:SRAA RS00645
gene id: 1458425:SRAA_RS00645
uniprot id: A0A060NM42
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1458425:SRAA RS11675
gene id: 1458425:SRAA_RS11675
uniprot id: A0A060NTE2
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

1458425:SRAA RS05835
gene id: 1458425:SRAA_RS05835
uniprot id: A0A060NQ20
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS02390
gene id: 1458425:SRAA_RS02390
uniprot id: A0A060NFT5
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

1458425:SRAA RS03430
gene id: 1458425:SRAA_RS03430
uniprot id: A0A060NG15
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS06250
gene id: 1458425:SRAA_RS06250
uniprot id: A0A060NQA6
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1458425:SRAA RS08165
gene id: 1458425:SRAA_RS08165
uniprot id: A0A060NRF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1458425:SRAA RS00220
gene id: 1458425:SRAA_RS00220
uniprot id: A0A060NLX2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1458425:SRAA RS05710
gene id: 1458425:SRAA_RS05710
uniprot id: A0A060NIY9
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1458425:SRAA RS07090
gene id: 1458425:SRAA_RS07090
uniprot id: A0A060NJG2
names: Similarity
messages: Belongs to the TPP enzyme family.

1458425:SRAA RS11635
gene id: 1458425:SRAA_RS11635
uniprot id: A0A060NIZ3
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO large chain family. Type I subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterohexadecamer of 8 large chains and 8 small chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

1458425:SRAA RS08130
gene id: 1458425:SRAA_RS08130
uniprot id: A0A060NJ46
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1458425:SRAA RS04155
gene id: 1458425:SRAA_RS04155
uniprot id: A0A060NG72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1458425:SRAA RS10605
gene id: 1458425:SRAA_RS10605
uniprot id: A0A060NKV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1458425:SRAA RS00180
gene id: 1458425:SRAA_RS00180
uniprot id: A0A060NF39
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1458425:SRAA RS04555
gene id: 1458425:SRAA_RS04555
uniprot id: A0A060NGC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1458425:SRAA RS09695
gene id: 1458425:SRAA_RS09695
uniprot id: A0A060NSB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1458425:SRAA RS10405
gene id: 1458425:SRAA_RS10405
uniprot id: A0A060NKT0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1458425:SRAA RS01700
gene id: 1458425:SRAA_RS01700
uniprot id: A0A060NL34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1458425:SRAA RS10840
gene id: 1458425:SRAA_RS10840
uniprot id: A0A060NK27
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1458425:SRAA RS00965
gene id: 1458425:SRAA_RS00965
uniprot id: A0A060NMA3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1458425:SRAA RS00830
gene id: 1458425:SRAA_RS00830
uniprot id: A0A060NH60
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1458425:SRAA RS09200
gene id: 1458425:SRAA_RS09200
uniprot id: A0A060NJG3
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1458425:SRAA RS02410
gene id: 1458425:SRAA_RS02410
uniprot id: A0A060NHU9
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1458425:SRAA RS02165
gene id: 1458425:SRAA_RS02165
uniprot id: A0A060NFP5
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1458425:SRAA RS03705
gene id: 1458425:SRAA_RS03705
uniprot id: A0A060NNU7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1458425:SRAA RS05555
gene id: 1458425:SRAA_RS05555
uniprot id: A0A060NIX4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS10180
gene id: 1458425:SRAA_RS10180
uniprot id: A0A060NQV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1458425:SRAA RS01620
gene id: 1458425:SRAA_RS01620
uniprot id: A0A060NGS7
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1458425:SRAA RS00575
gene id: 1458425:SRAA_RS00575
uniprot id: A0A060NH31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1458425:SRAA RS08825
gene id: 1458425:SRAA_RS08825
uniprot id: A0A060NJB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1458425:SRAA RS02840
gene id: 1458425:SRAA_RS02840
uniprot id: A0A060NHY7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1458425:SRAA RS00205
gene id: 1458425:SRAA_RS00205
uniprot id: A0A060NF42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1458425:SRAA RS04725
gene id: 1458425:SRAA_RS04725
uniprot id: A0A060NIN6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS11810
gene id: 1458425:SRAA_RS11810
uniprot id: A0A060NKH3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1458425:SRAA RS03555
gene id: 1458425:SRAA_RS03555
uniprot id: A0A060NI61
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS00525
gene id: 1458425:SRAA_RS00525
uniprot id: A0A060NH27
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1458425:SRAA RS08455
gene id: 1458425:SRAA_RS08455
uniprot id: A0A060NPS9
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1458425:SRAA RS03935
gene id: 1458425:SRAA_RS03935
uniprot id: A0A060NNZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1458425:SRAA RS08730
gene id: 1458425:SRAA_RS08730
uniprot id: A0A060NPY5
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1458425:SRAA RS09965
gene id: 1458425:SRAA_RS09965
uniprot id: A0A060NIH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1458425:SRAA RS08840
gene id: 1458425:SRAA_RS08840
uniprot id: A0A060NK22
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1458425:SRAA RS08835
gene id: 1458425:SRAA_RS08835
uniprot id: A0A060NRT2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1458425:SRAA RS04205
gene id: 1458425:SRAA_RS04205
uniprot id: A0A060NG77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1458425:SRAA RS00370
gene id: 1458425:SRAA_RS00370
uniprot id: A0A060NLZ6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1458425:SRAA RS03895
gene id: 1458425:SRAA_RS03895
uniprot id: A0A060NHL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

1458425:SRAA RS04960
gene id: 1458425:SRAA_RS04960
uniprot id: A0A060NGK8
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS07120
gene id: 1458425:SRAA_RS07120
uniprot id: A0A060NHC6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1458425:SRAA RS07420
gene id: 1458425:SRAA_RS07420
uniprot id: A0A060NR40
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1458425:SRAA RS04220
gene id: 1458425:SRAA_RS04220
uniprot id: A0A060NP49
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1458425:SRAA RS06635
gene id: 1458425:SRAA_RS06635
uniprot id: A0A060NJA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1458425:SRAA RS06420
gene id: 1458425:SRAA_RS06420
uniprot id: A0A060NIH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1458425:SRAA RS09390
gene id: 1458425:SRAA_RS09390
uniprot id: A0A060NK95
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

1458425:SRAA RS06540
gene id: 1458425:SRAA_RS06540
uniprot id: A0A060NJ90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1458425:SRAA RS01035
gene id: 1458425:SRAA_RS01035
uniprot id: A0A060NMB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1458425:SRAA RS10760
gene id: 1458425:SRAA_RS10760
uniprot id: A0A060NIP6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1458425:SRAA RS00450
gene id: 1458425:SRAA_RS00450
uniprot id: A0A060NH21
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1458425:SRAA RS00855
gene id: 1458425:SRAA_RS00855
uniprot id: A0A060NH65
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1458425:SRAA RS10630
gene id: 1458425:SRAA_RS10630
uniprot id: A0A060NKV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1458425:SRAA RS03415
gene id: 1458425:SRAA_RS03415
uniprot id: A0A060NLY6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1458425:SRAA RS07765
gene id: 1458425:SRAA_RS07765
uniprot id: A0A060NHM0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS00590
gene id: 1458425:SRAA_RS00590
uniprot id: A0A060NKJ8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1458425:SRAA RS07115
gene id: 1458425:SRAA_RS07115
uniprot id: A0A060NJG5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1458425:SRAA RS09285
gene id: 1458425:SRAA_RS09285
uniprot id: A0A060NS20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1458425:SRAA RS11905
gene id: 1458425:SRAA_RS11905
uniprot id: A0A060NTH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1458425:SRAA RS01960
gene id: 1458425:SRAA_RS01960
uniprot id: A0A060NHM8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1458425:SRAA RS06145
gene id: 1458425:SRAA_RS06145
uniprot id: A0A060NNG6
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

1458425:SRAA RS07080
gene id: 1458425:SRAA_RS07080
uniprot id: A0A060NP30
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1458425:SRAA RS05960
gene id: 1458425:SRAA_RS05960
uniprot id: A0A060NQ43
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458425:SRAA RS03500
gene id: 1458425:SRAA_RS03500
uniprot id: A0A060NI55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1458425:SRAA RS04795
gene id: 1458425:SRAA_RS04795
uniprot id: A0A060NPI0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1458425:SRAA RS02750
gene id: 1458425:SRAA_RS02750
uniprot id: A0A060NND3
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1458425:SRAA RS10965
gene id: 1458425:SRAA_RS10965
uniprot id: A0A060NR63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1458425:SRAA RS06860
gene id: 1458425:SRAA_RS06860
uniprot id: A0A060NNX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1458425:SRAA RS04905
gene id: 1458425:SRAA_RS04905
uniprot id: A0A060NIS3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1458425:SRAA RS11545
gene id: 1458425:SRAA_RS11545
uniprot id: A0A060NTC0
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

1458425:SRAA RS04200
gene id: 1458425:SRAA_RS04200
uniprot id: A0A060NIF1
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1458425:SRAA RS04215
gene id: 1458425:SRAA_RS04215
uniprot id: A0A060NMF2
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1458425:SRAA RS07425
gene id: 1458425:SRAA_RS07425
uniprot id: A0A060NJL7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1458425:SRAA RS08075
gene id: 1458425:SRAA_RS08075
uniprot id: A0A060NJ40
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1458425:SRAA RS11765
gene id: 1458425:SRAA_RS11765
uniprot id: A0A060NRN0
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1458425:SRAA RS08920
gene id: 1458425:SRAA_RS08920
uniprot id: A0A060NHZ1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1458425:SRAA RS02405
gene id: 1458425:SRAA_RS02405
uniprot id: A0A060NN86
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1458425:SRAA RS03330
gene id: 1458425:SRAA_RS03330
uniprot id: A0A060NI34
names: Subcellular Location Annotation
messages: Membrane

1458425:SRAA RS06505
gene id: 1458425:SRAA_RS06505
uniprot id: A0A060NQF9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1458425:SRAA RS07880
gene id: 1458425:SRAA_RS07880
uniprot id: A0A060NRA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1458425:SRAA RS11005
gene id: 1458425:SRAA_RS11005
uniprot id: A0A060NIR6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1458425:SRAA RS00975
gene id: 1458425:SRAA_RS00975
uniprot id: A0A060NFA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1458425:SRAA RS05580
gene id: 1458425:SRAA_RS05580
uniprot id: A0A060NIX5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1458425:SRAA RS11535
gene id: 1458425:SRAA_RS11535
uniprot id: A0A060NKC1
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.