1454201:NMS RS07030
gene id: 1454201:NMS_RS07030
uniprot id: W8W001
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1454201:NMS RS12230
gene id: 1454201:NMS_RS12230
uniprot id: W8VXV2
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1454201:NMS RS02015
gene id: 1454201:NMS_RS02015
uniprot id: W8VUA2
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1454201:NMS RS00270
gene id: 1454201:NMS_RS00270
uniprot id: W8VNT4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1454201:NMS RS10975
gene id: 1454201:NMS_RS10975
uniprot id: W8VWF7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS10805
gene id: 1454201:NMS_RS10805
uniprot id: W8VWE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1454201:NMS RS02780
gene id: 1454201:NMS_RS02780
uniprot id: W8VUG5
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1454201:NMS RS12715
gene id: 1454201:NMS_RS12715
uniprot id: W8VXX3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1454201:NMS RS12845
gene id: 1454201:NMS_RS12845
uniprot id: W8VS81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1454201:NMS RS04645
gene id: 1454201:NMS_RS04645
uniprot id: W8VWR2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1454201:NMS RS06975
gene id: 1454201:NMS_RS06975
uniprot id: W8VQ50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1454201:NMS RS12705
gene id: 1454201:NMS_RS12705
uniprot id: W8VT16
names: Similarity
messages: Belongs to the peptidase C40 family.

1454201:NMS RS03390
gene id: 1454201:NMS_RS03390
uniprot id: W8VNY5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1454201:NMS RS08410
gene id: 1454201:NMS_RS08410
uniprot id: W8VRR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1454201:NMS RS04455
gene id: 1454201:NMS_RS04455
uniprot id: W8VQ85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1454201:NMS RS01420
gene id: 1454201:NMS_RS01420
uniprot id: W8VZB7
names: Similarity
messages: Belongs to the TrpF family.

1454201:NMS RS06720
gene id: 1454201:NMS_RS06720
uniprot id: W8VQ21
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1454201:NMS RS12305
gene id: 1454201:NMS_RS12305
uniprot id: W8VXV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1454201:NMS RS07140
gene id: 1454201:NMS_RS07140
uniprot id: W8VVI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1454201:NMS RS01790
gene id: 1454201:NMS_RS01790
uniprot id: W8VPB2
names: Similarity
messages: Belongs to the EPSP synthase family.

1454201:NMS RS07585
gene id: 1454201:NMS_RS07585
uniprot id: W8VXA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1454201:NMS RS01070
gene id: 1454201:NMS_RS01070
uniprot id: W8VZA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1454201:NMS RS05635
gene id: 1454201:NMS_RS05635
uniprot id: W8VQQ6
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1454201:NMS RS02870
gene id: 1454201:NMS_RS02870
uniprot id: W8VZH7
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS08025
gene id: 1454201:NMS_RS08025
uniprot id: W8VXC3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

1454201:NMS RS12455
gene id: 1454201:NMS_RS12455
uniprot id: W8VSY8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1454201:NMS RS08405
gene id: 1454201:NMS_RS08405
uniprot id: W8VXD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1454201:NMS RS12930
gene id: 1454201:NMS_RS12930
uniprot id: W8VXY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1454201:NMS RS02645
gene id: 1454201:NMS_RS02645
uniprot id: W8VZG8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1454201:NMS RS04460
gene id: 1454201:NMS_RS04460
uniprot id: W8VZP3
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS03285
gene id: 1454201:NMS_RS03285
uniprot id: W8VUL6
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1454201:NMS RS02020
gene id: 1454201:NMS_RS02020
uniprot id: W8VNF2
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

1454201:NMS RS08565
gene id: 1454201:NMS_RS08565
uniprot id: W8W066
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS09440
gene id: 1454201:NMS_RS09440
uniprot id: W8VS30
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1454201:NMS RS00635
gene id: 1454201:NMS_RS00635
uniprot id: W8VZ85
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1454201:NMS RS07385
gene id: 1454201:NMS_RS07385
uniprot id: W8VVK6
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1454201:NMS RS05830
gene id: 1454201:NMS_RS05830
uniprot id: W8VPT1
names: Similarity
messages: Belongs to the ParB family.

1454201:NMS RS01095
gene id: 1454201:NMS_RS01095
uniprot id: W8VZA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1454201:NMS RS02555
gene id: 1454201:NMS_RS02555
uniprot id: W8VNL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1454201:NMS RS05230
gene id: 1454201:NMS_RS05230
uniprot id: W8VWW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1454201:NMS RS01165
gene id: 1454201:NMS_RS01165
uniprot id: W8VP46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1454201:NMS RS13145
gene id: 1454201:NMS_RS13145
uniprot id: W8VT50
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1454201:NMS RS13125
gene id: 1454201:NMS_RS13125
uniprot id: W8W0R0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1454201:NMS RS04550
gene id: 1454201:NMS_RS04550
uniprot id: W8VPA9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1454201:NMS RS02465
gene id: 1454201:NMS_RS02465
uniprot id: W8VPI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1454201:NMS RS11815
gene id: 1454201:NMS_RS11815
uniprot id: W8VRU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1454201:NMS RS08085
gene id: 1454201:NMS_RS08085
uniprot id: W8VRL9
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS05190
gene id: 1454201:NMS_RS05190
uniprot id: W8VPJ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS08685
gene id: 1454201:NMS_RS08685
uniprot id: W8W071
names: Similarity
messages: Belongs to the AIR synthase family.

1454201:NMS RS03655
gene id: 1454201:NMS_RS03655
uniprot id: W8VUP3
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1454201:NMS RS01040
gene id: 1454201:NMS_RS01040
uniprot id: W8VZA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1454201:NMS RS05200
gene id: 1454201:NMS_RS05200
uniprot id: W8VZS5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1454201:NMS RS05255
gene id: 1454201:NMS_RS05255
uniprot id: W8VWW1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1454201:NMS RS03985
gene id: 1454201:NMS_RS03985
uniprot id: W8VZM3
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1454201:NMS RS02925
gene id: 1454201:NMS_RS02925
uniprot id: W8VWB3
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1454201:NMS RS07335
gene id: 1454201:NMS_RS07335
uniprot id: W8VVK3
names: Similarity
messages: Belongs to the peptidase S14 family.

1454201:NMS RS03010
gene id: 1454201:NMS_RS03010
uniprot id: W8VZI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1454201:NMS RS11450
gene id: 1454201:NMS_RS11450
uniprot id: W8VXR9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1454201:NMS RS03190
gene id: 1454201:NMS_RS03190
uniprot id: W8VUJ9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1454201:NMS RS11010
gene id: 1454201:NMS_RS11010
uniprot id: W8W0H0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1454201:NMS RS10000
gene id: 1454201:NMS_RS10000
uniprot id: W8VXK6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS08675
gene id: 1454201:NMS_RS08675
uniprot id: W8VQQ0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1454201:NMS RS06140
gene id: 1454201:NMS_RS06140
uniprot id: W8VZW5
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1454201:NMS RS01565
gene id: 1454201:NMS_RS01565
uniprot id: W8VP86
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS12950
gene id: 1454201:NMS_RS12950
uniprot id: W8W0Q3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1454201:NMS RS00710
gene id: 1454201:NMS_RS00710
uniprot id: W8VZ88
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

1454201:NMS RS01385
gene id: 1454201:NMS_RS01385
uniprot id: W8VN79
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1454201:NMS RS09065
gene id: 1454201:NMS_RS09065
uniprot id: W8VRY4
names: Similarity
messages: Belongs to the LOG family.

1454201:NMS RS07400
gene id: 1454201:NMS_RS07400
uniprot id: W8VQ95
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1454201:NMS RS02305
gene id: 1454201:NMS_RS02305
uniprot id: W8VUC7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1454201:NMS RS01675
gene id: 1454201:NMS_RS01675
uniprot id: W8VZC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1454201:NMS RS03480
gene id: 1454201:NMS_RS03480
uniprot id: W8VWG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1454201:NMS RS07775
gene id: 1454201:NMS_RS07775
uniprot id: W8VXB1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1454201:NMS RS00035
gene id: 1454201:NMS_RS00035
uniprot id: W8VZ60
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

1454201:NMS RS01125
gene id: 1454201:NMS_RS01125
uniprot id: W8VVX0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1454201:NMS RS08985
gene id: 1454201:NMS_RS08985
uniprot id: W8VQT1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1454201:NMS RS09690
gene id: 1454201:NMS_RS09690
uniprot id: W8VS57
names: Similarity
messages: Belongs to the FPG family.

1454201:NMS RS08930
gene id: 1454201:NMS_RS08930
uniprot id: W8VVY8
names: Similarity
messages: Belongs to the IMPACT family.

1454201:NMS RS03030
gene id: 1454201:NMS_RS03030
uniprot id: W8VZI4
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

1454201:NMS RS02035
gene id: 1454201:NMS_RS02035
uniprot id: W8VW44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1454201:NMS RS00605
gene id: 1454201:NMS_RS00605
uniprot id: W8VNW8
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1454201:NMS RS01960
gene id: 1454201:NMS_RS01960
uniprot id: W8VW38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1454201:NMS RS11805
gene id: 1454201:NMS_RS11805
uniprot id: W8W0K4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1454201:NMS RS00205
gene id: 1454201:NMS_RS00205
uniprot id: W8VVP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1454201:NMS RS03770
gene id: 1454201:NMS_RS03770
uniprot id: W8VUP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1454201:NMS RS09000
gene id: 1454201:NMS_RS09000
uniprot id: W8VXG4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS13280
gene id: 1454201:NMS_RS13280
uniprot id: W8VXZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1454201:NMS RS11310
gene id: 1454201:NMS_RS11310
uniprot id: W8VXR3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1454201:NMS RS10495
gene id: 1454201:NMS_RS10495
uniprot id: W8VSH4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1454201:NMS RS07915
gene id: 1454201:NMS_RS07915
uniprot id: W8VQG1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1454201:NMS RS10055
gene id: 1454201:NMS_RS10055
uniprot id: W8VR63
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1454201:NMS RS07325
gene id: 1454201:NMS_RS07325
uniprot id: W8W012
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS10690
gene id: 1454201:NMS_RS10690
uniprot id: W8VSJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1454201:NMS RS05080
gene id: 1454201:NMS_RS05080
uniprot id: W8VV17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1454201:NMS RS01145
gene id: 1454201:NMS_RS01145
uniprot id: W8VZA6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1454201:NMS RS06900
gene id: 1454201:NMS_RS06900
uniprot id: W8VZZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1454201:NMS RS06330
gene id: 1454201:NMS_RS06330
uniprot id: W8VQY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1454201:NMS RS01820
gene id: 1454201:NMS_RS01820
uniprot id: W8VW26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1454201:NMS RS10630
gene id: 1454201:NMS_RS10630
uniprot id: W8W0F4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1454201:NMS RS03075
gene id: 1454201:NMS_RS03075
uniprot id: W8VPR2
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1454201:NMS RS05220
gene id: 1454201:NMS_RS05220
uniprot id: W8VQH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1454201:NMS RS06015
gene id: 1454201:NMS_RS06015
uniprot id: W8VZW0
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS06370
gene id: 1454201:NMS_RS06370
uniprot id: W8VPY3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1454201:NMS RS01930
gene id: 1454201:NMS_RS01930
uniprot id: W8VPC6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1454201:NMS RS06285
gene id: 1454201:NMS_RS06285
uniprot id: W8VQX9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1454201:NMS RS00905
gene id: 1454201:NMS_RS00905
uniprot id: W8VVV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1454201:NMS RS07715
gene id: 1454201:NMS_RS07715
uniprot id: W8VRE4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1454201:NMS RS03080
gene id: 1454201:NMS_RS03080
uniprot id: W8VZI6
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1454201:NMS RS09160
gene id: 1454201:NMS_RS09160
uniprot id: W8VXH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1454201:NMS RS11365
gene id: 1454201:NMS_RS11365
uniprot id: W8VWJ1
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1454201:NMS RS10545
gene id: 1454201:NMS_RS10545
uniprot id: W8VSH8
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1454201:NMS RS04620
gene id: 1454201:NMS_RS04620
uniprot id: W8VPB6
names: Similarity
messages: Belongs to the UPF0102 family.

1454201:NMS RS03545
gene id: 1454201:NMS_RS03545
uniprot id: W8VZK5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 3-HAO family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.

1454201:NMS RS01600
gene id: 1454201:NMS_RS01600
uniprot id: W8VW07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1454201:NMS RS08865
gene id: 1454201:NMS_RS08865
uniprot id: W8VRW2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

1454201:NMS RS06065
gene id: 1454201:NMS_RS06065
uniprot id: W8VZW2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1454201:NMS RS05530
gene id: 1454201:NMS_RS05530
uniprot id: W8VV62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1454201:NMS RS00260
gene id: 1454201:NMS_RS00260
uniprot id: W8VTW4
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1454201:NMS RS03430
gene id: 1454201:NMS_RS03430
uniprot id: W8VWG5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1454201:NMS RS05720
gene id: 1454201:NMS_RS05720
uniprot id: W8VX14
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1454201:NMS RS12375
gene id: 1454201:NMS_RS12375
uniprot id: W8VS17
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1454201:NMS RS04960
gene id: 1454201:NMS_RS04960
uniprot id: W8VZR5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS01550
gene id: 1454201:NMS_RS01550
uniprot id: W8VW03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1454201:NMS RS02540
gene id: 1454201:NMS_RS02540
uniprot id: W8VZG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1454201:NMS RS07680
gene id: 1454201:NMS_RS07680
uniprot id: W8VVN1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1454201:NMS RS10430
gene id: 1454201:NMS_RS10430
uniprot id: W8VWC6
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS11780
gene id: 1454201:NMS_RS11780
uniprot id: W8W0K3
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS01030
gene id: 1454201:NMS_RS01030
uniprot id: W8VN47
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1454201:NMS RS06555
gene id: 1454201:NMS_RS06555
uniprot id: W8VZY2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1454201:NMS RS05205
gene id: 1454201:NMS_RS05205
uniprot id: W8VWV9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS10635
gene id: 1454201:NMS_RS10635
uniprot id: W8VXN4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1454201:NMS RS04320
gene id: 1454201:NMS_RS04320
uniprot id: W8VUU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1454201:NMS RS07925
gene id: 1454201:NMS_RS07925
uniprot id: W8VVQ3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1454201:NMS RS06400
gene id: 1454201:NMS_RS06400
uniprot id: W8VQZ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1454201:NMS RS10945
gene id: 1454201:NMS_RS10945
uniprot id: W8VXP7
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS11775
gene id: 1454201:NMS_RS11775
uniprot id: W8VSS9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1454201:NMS RS02630
gene id: 1454201:NMS_RS02630
uniprot id: W8VUF2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1454201:NMS RS11250
gene id: 1454201:NMS_RS11250
uniprot id: W8VRM4
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS07130
gene id: 1454201:NMS_RS07130
uniprot id: W8W004
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1454201:NMS RS11445
gene id: 1454201:NMS_RS11445
uniprot id: W8W0I9
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1454201:NMS RS11940
gene id: 1454201:NMS_RS11940
uniprot id: W8VSU2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1454201:NMS RS11740
gene id: 1454201:NMS_RS11740
uniprot id: W8VRT4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1454201:NMS RS11105
gene id: 1454201:NMS_RS11105
uniprot id: W8W0H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1454201:NMS RS12280
gene id: 1454201:NMS_RS12280
uniprot id: W8W0M5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1454201:NMS RS03970
gene id: 1454201:NMS_RS03970
uniprot id: W8VUR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1454201:NMS RS01155
gene id: 1454201:NMS_RS01155
uniprot id: W8VU40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1454201:NMS RS01180
gene id: 1454201:NMS_RS01180
uniprot id: W8VU41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1454201:NMS RS07085
gene id: 1454201:NMS_RS07085
uniprot id: W8VX83
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1454201:NMS RS09385
gene id: 1454201:NMS_RS09385
uniprot id: W8VW27
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1454201:NMS RS09250
gene id: 1454201:NMS_RS09250
uniprot id: W8W095
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1454201:NMS RS01410
gene id: 1454201:NMS_RS01410
uniprot id: W8VN82
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS09465
gene id: 1454201:NMS_RS09465
uniprot id: W8VXI4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1454201:NMS RS08915
gene id: 1454201:NMS_RS08915
uniprot id: W8VRW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1454201:NMS RS00220
gene id: 1454201:NMS_RS00220
uniprot id: W8VNS8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS12480
gene id: 1454201:NMS_RS12480
uniprot id: W8W0N4
names: Subcellular Location Annotation
messages: Secreted

1454201:NMS RS01360
gene id: 1454201:NMS_RS01360
uniprot id: W8VN77
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1454201:NMS RS06700
gene id: 1454201:NMS_RS06700
uniprot id: W8VR22
names: Similarity
messages: Belongs to the asparagine synthetase family.

1454201:NMS RS01100
gene id: 1454201:NMS_RS01100
uniprot id: W8VVW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1454201:NMS RS00370
gene id: 1454201:NMS_RS00370
uniprot id: W8VMV6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS03265
gene id: 1454201:NMS_RS03265
uniprot id: W8VNX0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1454201:NMS RS11670
gene id: 1454201:NMS_RS11670
uniprot id: W8VSS1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1454201:NMS RS04065
gene id: 1454201:NMS_RS04065
uniprot id: W8VWL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1454201:NMS RS11060
gene id: 1454201:NMS_RS11060
uniprot id: W8W0H2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

1454201:NMS RS10665
gene id: 1454201:NMS_RS10665
uniprot id: W8VRG6
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1454201:NMS RS03530
gene id: 1454201:NMS_RS03530
uniprot id: W8VUN4
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1454201:NMS RS08100
gene id: 1454201:NMS_RS08100
uniprot id: W8VVS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1454201:NMS RS07405
gene id: 1454201:NMS_RS07405
uniprot id: W8VRA3
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1454201:NMS RS03515
gene id: 1454201:NMS_RS03515
uniprot id: W8VPY7
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1454201:NMS RS00055
gene id: 1454201:NMS_RS00055
uniprot id: W8VNQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1454201:NMS RS01340
gene id: 1454201:NMS_RS01340
uniprot id: W8VP64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1454201:NMS RS06010
gene id: 1454201:NMS_RS06010
uniprot id: W8VQU9
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

1454201:NMS RS11570
gene id: 1454201:NMS_RS11570
uniprot id: W8VRR3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1454201:NMS RS02710
gene id: 1454201:NMS_RS02710
uniprot id: W8VNN3
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1454201:NMS RS01370
gene id: 1454201:NMS_RS01370
uniprot id: W8VZB5
names: Caution
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1454201:NMS RS07065
gene id: 1454201:NMS_RS07065
uniprot id: W8VVI4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1454201:NMS RS13140
gene id: 1454201:NMS_RS13140
uniprot id: W8VSA8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1454201:NMS RS10065
gene id: 1454201:NMS_RS10065
uniprot id: W8W0C9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1454201:NMS RS01450
gene id: 1454201:NMS_RS01450
uniprot id: W8VVZ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS04765
gene id: 1454201:NMS_RS04765
uniprot id: W8VZQ7
names: Similarity
messages: Belongs to the DtxR/MntR family.

1454201:NMS RS08775
gene id: 1454201:NMS_RS08775
uniprot id: W8VXF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1454201:NMS RS04375
gene id: 1454201:NMS_RS04375
uniprot id: W8VWN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1454201:NMS RS08175
gene id: 1454201:NMS_RS08175
uniprot id: W8VRN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1454201:NMS RS09300
gene id: 1454201:NMS_RS09300
uniprot id: W8W097
names: Similarity
messages: Belongs to the DEAD box helicase family.

1454201:NMS RS07885
gene id: 1454201:NMS_RS07885
uniprot id: W8W036
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1454201:NMS RS06815
gene id: 1454201:NMS_RS06815
uniprot id: W8VQ33
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS13090
gene id: 1454201:NMS_RS13090
uniprot id: W8VSA3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1454201:NMS RS10840
gene id: 1454201:NMS_RS10840
uniprot id: W8VSK3
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS12680
gene id: 1454201:NMS_RS12680
uniprot id: W8VXX2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS02580
gene id: 1454201:NMS_RS02580
uniprot id: W8VNL8
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS02090
gene id: 1454201:NMS_RS02090
uniprot id: W8VPE6
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.

1454201:NMS RS03785
gene id: 1454201:NMS_RS03785
uniprot id: W8VZL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1454201:NMS RS02605
gene id: 1454201:NMS_RS02605
uniprot id: W8VUF0
names: Similarity
messages: Belongs to the asparaginase 1 family.

1454201:NMS RS07245
gene id: 1454201:NMS_RS07245
uniprot id: W8VQ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1454201:NMS RS12015
gene id: 1454201:NMS_RS12015
uniprot id: W8VSU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1454201:NMS RS05415
gene id: 1454201:NMS_RS05415
uniprot id: W8VWX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

1454201:NMS RS06695
gene id: 1454201:NMS_RS06695
uniprot id: W8VQ18
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1454201:NMS RS05660
gene id: 1454201:NMS_RS05660
uniprot id: W8VQR0
names: Similarity
messages: Belongs to the peptidase S51 family.

1454201:NMS RS13300
gene id: 1454201:NMS_RS13300
uniprot id: W8W0R7
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1454201:NMS RS02635
gene id: 1454201:NMS_RS02635
uniprot id: W8VNM4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1454201:NMS RS12145
gene id: 1454201:NMS_RS12145
uniprot id: W8VSV9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1454201:NMS RS04585
gene id: 1454201:NMS_RS04585
uniprot id: W8VWQ6
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1454201:NMS RS04290
gene id: 1454201:NMS_RS04290
uniprot id: W8VZN5
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1454201:NMS RS05440
gene id: 1454201:NMS_RS05440
uniprot id: W8VPN0
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1454201:NMS RS08730
gene id: 1454201:NMS_RS08730
uniprot id: W8W073
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1454201:NMS RS11595
gene id: 1454201:NMS_RS11595
uniprot id: W8VRR7
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1454201:NMS RS03840
gene id: 1454201:NMS_RS03840
uniprot id: W8VUQ2
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1454201:NMS RS13070
gene id: 1454201:NMS_RS13070
uniprot id: W8VT44
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS01615
gene id: 1454201:NMS_RS01615
uniprot id: W8VZC5
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1454201:NMS RS02395
gene id: 1454201:NMS_RS02395
uniprot id: W8VZF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1454201:NMS RS06595
gene id: 1454201:NMS_RS06595
uniprot id: W8VR11
names: Similarity
messages: Belongs to the arginase family.

1454201:NMS RS01135
gene id: 1454201:NMS_RS01135
uniprot id: W8VN54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1454201:NMS RS06880
gene id: 1454201:NMS_RS06880
uniprot id: W8VX75
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1454201:NMS RS08995
gene id: 1454201:NMS_RS08995
uniprot id: W8W084
names: Similarity
messages: Belongs to the RNA polymerase subunit omega family.

1454201:NMS RS04390
gene id: 1454201:NMS_RS04390
uniprot id: W8VQ79
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1454201:NMS RS05015
gene id: 1454201:NMS_RS05015
uniprot id: W8VWU3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1454201:NMS RS10195
gene id: 1454201:NMS_RS10195
uniprot id: W8VXL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1454201:NMS RS01110
gene id: 1454201:NMS_RS01110
uniprot id: W8VN52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1454201:NMS RS01010
gene id: 1454201:NMS_RS01010
uniprot id: W8VN44
names: Similarity
messages: Belongs to the citrate synthase family.

1454201:NMS RS12595
gene id: 1454201:NMS_RS12595
uniprot id: W8VT01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1454201:NMS RS00520
gene id: 1454201:NMS_RS00520
uniprot id: W8VTY5
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1454201:NMS RS01445
gene id: 1454201:NMS_RS01445
uniprot id: W8VZB8
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1454201:NMS RS00085
gene id: 1454201:NMS_RS00085
uniprot id: W8VVN2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1454201:NMS RS07160
gene id: 1454201:NMS_RS07160
uniprot id: W8VX85
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1454201:NMS RS10610
gene id: 1454201:NMS_RS10610
uniprot id: W8W0F3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

1454201:NMS RS08490
gene id: 1454201:NMS_RS08490
uniprot id: W8W063
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1454201:NMS RS01045
gene id: 1454201:NMS_RS01045
uniprot id: W8VVW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1454201:NMS RS11275
gene id: 1454201:NMS_RS11275
uniprot id: W8VRM7
names: Similarity
messages: Belongs to the SUI1 family.

1454201:NMS RS01645
gene id: 1454201:NMS_RS01645
uniprot id: W8VW10
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1454201:NMS RS04050
gene id: 1454201:NMS_RS04050
uniprot id: W8VP53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

1454201:NMS RS00855
gene id: 1454201:NMS_RS00855
uniprot id: W8VU20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1454201:NMS RS11205
gene id: 1454201:NMS_RS11205
uniprot id: W8VRL8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

1454201:NMS RS03945
gene id: 1454201:NMS_RS03945
uniprot id: W8VUQ9
names: Similarity
messages: Belongs to the peptidase S41A family.

1454201:NMS RS03890
gene id: 1454201:NMS_RS03890
uniprot id: W8VUQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1454201:NMS RS03340
gene id: 1454201:NMS_RS03340
uniprot id: W8VNX9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1454201:NMS RS12255
gene id: 1454201:NMS_RS12255
uniprot id: W8VS02
names: Similarity
messages: Belongs to the CarB family.

1454201:NMS RS01885
gene id: 1454201:NMS_RS01885
uniprot id: W8VZD7
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1454201:NMS RS11085
gene id: 1454201:NMS_RS11085
uniprot id: W8W0H3
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

1454201:NMS RS01090
gene id: 1454201:NMS_RS01090
uniprot id: W8VP38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1454201:NMS RS03180
gene id: 1454201:NMS_RS03180
uniprot id: W8VZJ0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1454201:NMS RS06830
gene id: 1454201:NMS_RS06830
uniprot id: W8VX73
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS04195
gene id: 1454201:NMS_RS04195
uniprot id: W8VWM4
names: Similarity
messages: Belongs to the GARS family.

1454201:NMS RS05370
gene id: 1454201:NMS_RS05370
uniprot id: W8VV46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1454201:NMS RS12670
gene id: 1454201:NMS_RS12670
uniprot id: W8VT09
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1454201:NMS RS07960
gene id: 1454201:NMS_RS07960
uniprot id: W8VVQ7
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1454201:NMS RS11600
gene id: 1454201:NMS_RS11600
uniprot id: W8VSR5
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1454201:NMS RS03990
gene id: 1454201:NMS_RS03990
uniprot id: W8VWK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1454201:NMS RS09655
gene id: 1454201:NMS_RS09655
uniprot id: W8VXJ2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1454201:NMS RS02730
gene id: 1454201:NMS_RS02730
uniprot id: W8VUG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1454201:NMS RS11795
gene id: 1454201:NMS_RS11795
uniprot id: W8VRU0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1454201:NMS RS03760
gene id: 1454201:NMS_RS03760
uniprot id: W8VZL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Membrane

1454201:NMS RS02515
gene id: 1454201:NMS_RS02515
uniprot id: W8VW84
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1454201:NMS RS11695
gene id: 1454201:NMS_RS11695
uniprot id: W8VSS3
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1454201:NMS RS01235
gene id: 1454201:NMS_RS01235
uniprot id: W8VN62
names: Similarity
messages: Belongs to the UPF0758 family.

1454201:NMS RS05125
gene id: 1454201:NMS_RS05125
uniprot id: W8VPI6
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1454201:NMS RS07760
gene id: 1454201:NMS_RS07760
uniprot id: W8VQD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1454201:NMS RS06385
gene id: 1454201:NMS_RS06385
uniprot id: W8VX56
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1454201:NMS RS08265
gene id: 1454201:NMS_RS08265
uniprot id: W8VQL3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1454201:NMS RS03905
gene id: 1454201:NMS_RS03905
uniprot id: W8VZM0
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1454201:NMS RS05745
gene id: 1454201:NMS_RS05745
uniprot id: W8VZU8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1454201:NMS RS03185
gene id: 1454201:NMS_RS03185
uniprot id: W8VWC9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1454201:NMS RS03320
gene id: 1454201:NMS_RS03320
uniprot id: W8VPW6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1454201:NMS RS03095
gene id: 1454201:NMS_RS03095
uniprot id: W8VNT5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1454201:NMS RS08765
gene id: 1454201:NMS_RS08765
uniprot id: W8VQQ8
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS11830
gene id: 1454201:NMS_RS11830
uniprot id: W8VXT5
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS01150
gene id: 1454201:NMS_RS01150
uniprot id: W8VVX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1454201:NMS RS01785
gene id: 1454201:NMS_RS01785
uniprot id: W8VND0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1454201:NMS RS02700
gene id: 1454201:NMS_RS02700
uniprot id: W8VW97
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

1454201:NMS RS13230
gene id: 1454201:NMS_RS13230
uniprot id: W8VXZ4
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS02235
gene id: 1454201:NMS_RS02235
uniprot id: W8VNH6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS05325
gene id: 1454201:NMS_RS05325
uniprot id: W8VV42
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1454201:NMS RS05430
gene id: 1454201:NMS_RS05430
uniprot id: W8VZT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1454201:NMS RS06085
gene id: 1454201:NMS_RS06085
uniprot id: W8VZW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

1454201:NMS RS00175
gene id: 1454201:NMS_RS00175
uniprot id: W8VZ66
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1454201:NMS RS10060
gene id: 1454201:NMS_RS10060
uniprot id: W8VSA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1454201:NMS RS09615
gene id: 1454201:NMS_RS09615
uniprot id: W8VW47
names: Similarity
messages: Belongs to the DEAD box helicase family.

1454201:NMS RS06645
gene id: 1454201:NMS_RS06645
uniprot id: W8VR17
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1454201:NMS RS01175
gene id: 1454201:NMS_RS01175
uniprot id: W8VVX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1454201:NMS RS09365
gene id: 1454201:NMS_RS09365
uniprot id: W8VQX6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1454201:NMS RS03380
gene id: 1454201:NMS_RS03380
uniprot id: W8VWG1
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1454201:NMS RS09410
gene id: 1454201:NMS_RS09410
uniprot id: W8VW29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

1454201:NMS RS11845
gene id: 1454201:NMS_RS11845
uniprot id: W8VST5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1454201:NMS RS06320
gene id: 1454201:NMS_RS06320
uniprot id: W8VVC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1454201:NMS RS07995
gene id: 1454201:NMS_RS07995
uniprot id: W8W042
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1454201:NMS RS06280
gene id: 1454201:NMS_RS06280
uniprot id: W8VPX0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1454201:NMS RS08660
gene id: 1454201:NMS_RS08660
uniprot id: W8W070
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1454201:NMS RS08165
gene id: 1454201:NMS_RS08165
uniprot id: W8VXC9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1454201:NMS RS09395
gene id: 1454201:NMS_RS09395
uniprot id: W8VS24
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS02110
gene id: 1454201:NMS_RS02110
uniprot id: W8VPE8
names: Similarity
messages: Belongs to the peptidase S41A family.

1454201:NMS RS12745
gene id: 1454201:NMS_RS12745
uniprot id: W8VWX0
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS09695
gene id: 1454201:NMS_RS09695
uniprot id: W8W0B4
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1454201:NMS RS07445
gene id: 1454201:NMS_RS07445
uniprot id: W8VX97
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS08170
gene id: 1454201:NMS_RS08170
uniprot id: W8VVT0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1454201:NMS RS01320
gene id: 1454201:NMS_RS01320
uniprot id: W8VZB3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1454201:NMS RS05575
gene id: 1454201:NMS_RS05575
uniprot id: W8VV66
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1454201:NMS RS01245
gene id: 1454201:NMS_RS01245
uniprot id: W8VZB0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1454201:NMS RS07675
gene id: 1454201:NMS_RS07675
uniprot id: W8VXA7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1454201:NMS RS11355
gene id: 1454201:NMS_RS11355
uniprot id: W8W0I5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1454201:NMS RS10970
gene id: 1454201:NMS_RS10970
uniprot id: W8VXP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1454201:NMS RS07150
gene id: 1454201:NMS_RS07150
uniprot id: W8VR72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1454201:NMS RS11840
gene id: 1454201:NMS_RS11840
uniprot id: W8VRU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1454201:NMS RS07780
gene id: 1454201:NMS_RS07780
uniprot id: W8VVN9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1454201:NMS RS12210
gene id: 1454201:NMS_RS12210
uniprot id: W8VWR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1454201:NMS RS00810
gene id: 1454201:NMS_RS00810
uniprot id: W8VN26
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1454201:NMS RS07870
gene id: 1454201:NMS_RS07870
uniprot id: W8VVP7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1454201:NMS RS07250
gene id: 1454201:NMS_RS07250
uniprot id: W8VR83
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1454201:NMS RS02290
gene id: 1454201:NMS_RS02290
uniprot id: W8VPG9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1454201:NMS RS06025
gene id: 1454201:NMS_RS06025
uniprot id: W8VVA0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1454201:NMS RS00075
gene id: 1454201:NMS_RS00075
uniprot id: W8VMS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1454201:NMS RS10490
gene id: 1454201:NMS_RS10490
uniprot id: W8VRF0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS01260
gene id: 1454201:NMS_RS01260
uniprot id: W8VN64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1454201:NMS RS00640
gene id: 1454201:NMS_RS00640
uniprot id: W8VVS3
names: Subcellular Location Annotation
messages: Mitochondrion

1454201:NMS RS00405
gene id: 1454201:NMS_RS00405
uniprot id: W8VZ75
names: Similarity
messages: Belongs to the nitroreductase family.

1454201:NMS RS02405
gene id: 1454201:NMS_RS02405
uniprot id: W8VUD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1454201:NMS RS12940
gene id: 1454201:NMS_RS12940
uniprot id: W8VS90
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1454201:NMS RS08770
gene id: 1454201:NMS_RS08770
uniprot id: W8VRV1
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS02895
gene id: 1454201:NMS_RS02895
uniprot id: W8VZH8
names: Similarity
messages: Belongs to the pyruvate kinase family.

1454201:NMS RS01220
gene id: 1454201:NMS_RS01220
uniprot id: W8VZA9
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1454201:NMS RS03595
gene id: 1454201:NMS_RS03595
uniprot id: W8VWH8
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1454201:NMS RS00815
gene id: 1454201:NMS_RS00815
uniprot id: W8VP08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1454201:NMS RS13085
gene id: 1454201:NMS_RS13085
uniprot id: W8VWZ2
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1454201:NMS RS04995
gene id: 1454201:NMS_RS04995
uniprot id: W8VV10
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS13060
gene id: 1454201:NMS_RS13060
uniprot id: W8VWZ1
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1454201:NMS RS12885
gene id: 1454201:NMS_RS12885
uniprot id: W8VWY1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1454201:NMS RS09045
gene id: 1454201:NMS_RS09045
uniprot id: W8W086
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1454201:NMS RS09610
gene id: 1454201:NMS_RS09610
uniprot id: W8VXJ0
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1454201:NMS RS09400
gene id: 1454201:NMS_RS09400
uniprot id: W8W0A1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1454201:NMS RS13135
gene id: 1454201:NMS_RS13135
uniprot id: W8VWZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1454201:NMS RS03385
gene id: 1454201:NMS_RS03385
uniprot id: W8VUM3
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1454201:NMS RS01160
gene id: 1454201:NMS_RS01160
uniprot id: W8VN55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1454201:NMS RS09675
gene id: 1454201:NMS_RS09675
uniprot id: W8VXJ3
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1454201:NMS RS09195
gene id: 1454201:NMS_RS09195
uniprot id: W8VS01
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1454201:NMS RS07835
gene id: 1454201:NMS_RS07835
uniprot id: W8W034
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1454201:NMS RS03570
gene id: 1454201:NMS_RS03570
uniprot id: W8VWH6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1454201:NMS RS08835
gene id: 1454201:NMS_RS08835
uniprot id: W8VQR5
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1454201:NMS RS13080
gene id: 1454201:NMS_RS13080
uniprot id: W8VXY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1454201:NMS RS11240
gene id: 1454201:NMS_RS11240
uniprot id: W8VXR0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1454201:NMS RS02965
gene id: 1454201:NMS_RS02965
uniprot id: W8VWB5
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1454201:NMS RS12490
gene id: 1454201:NMS_RS12490
uniprot id: W8VWU4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1454201:NMS RS01455
gene id: 1454201:NMS_RS01455
uniprot id: W8VU54
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1454201:NMS RS06500
gene id: 1454201:NMS_RS06500
uniprot id: W8VR02
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1454201:NMS RS02970
gene id: 1454201:NMS_RS02970
uniprot id: W8VUI1
names: Subunit
messages: Homodimer.

1454201:NMS RS13160
gene id: 1454201:NMS_RS13160
uniprot id: W8VWZ5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1454201:NMS RS06335
gene id: 1454201:NMS_RS06335
uniprot id: W8VZX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1454201:NMS RS02985
gene id: 1454201:NMS_RS02985
uniprot id: W8VZI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

1454201:NMS RS05750
gene id: 1454201:NMS_RS05750
uniprot id: W8VX16
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS12720
gene id: 1454201:NMS_RS12720
uniprot id: W8VWW9
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1454201:NMS RS09995
gene id: 1454201:NMS_RS09995
uniprot id: W8W0C6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1454201:NMS RS00625
gene id: 1454201:NMS_RS00625
uniprot id: W8VMY9
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1454201:NMS RS02085
gene id: 1454201:NMS_RS02085
uniprot id: W8VNF9
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

1454201:NMS RS08855
gene id: 1454201:NMS_RS08855
uniprot id: W8VVY1
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS03630
gene id: 1454201:NMS_RS03630
uniprot id: W8VUP2
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1454201:NMS RS13150
gene id: 1454201:NMS_RS13150
uniprot id: W8W0R1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1454201:NMS RS12725
gene id: 1454201:NMS_RS12725
uniprot id: W8VS68
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS09870
gene id: 1454201:NMS_RS09870
uniprot id: W8W0C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1454201:NMS RS12915
gene id: 1454201:NMS_RS12915
uniprot id: W8VS87
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1454201:NMS RS06480
gene id: 1454201:NMS_RS06480
uniprot id: W8VZX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1454201:NMS RS06240
gene id: 1454201:NMS_RS06240
uniprot id: W8VQX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS08550
gene id: 1454201:NMS_RS08550
uniprot id: W8VXE5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1454201:NMS RS03810
gene id: 1454201:NMS_RS03810
uniprot id: W8VZL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1454201:NMS RS09915
gene id: 1454201:NMS_RS09915
uniprot id: W8W0C3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1454201:NMS RS04045
gene id: 1454201:NMS_RS04045
uniprot id: W8VUR9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1454201:NMS RS02880
gene id: 1454201:NMS_RS02880
uniprot id: W8VUH2
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1454201:NMS RS06505
gene id: 1454201:NMS_RS06505
uniprot id: W8VZY0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1454201:NMS RS07375
gene id: 1454201:NMS_RS07375
uniprot id: W8W014
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1454201:NMS RS10765
gene id: 1454201:NMS_RS10765
uniprot id: W8VSJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1454201:NMS RS07115
gene id: 1454201:NMS_RS07115
uniprot id: W8VQ65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1454201:NMS RS11395
gene id: 1454201:NMS_RS11395
uniprot id: W8VRP0
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS06490
gene id: 1454201:NMS_RS06490
uniprot id: W8VVE0
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1454201:NMS RS08740
gene id: 1454201:NMS_RS08740
uniprot id: W8VQQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1454201:NMS RS12000
gene id: 1454201:NMS_RS12000
uniprot id: W8VXU2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS00560
gene id: 1454201:NMS_RS00560
uniprot id: W8VTY8
names: Similarity
messages: Belongs to the HSP15 family.

1454201:NMS RS08070
gene id: 1454201:NMS_RS08070
uniprot id: W8W045
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1454201:NMS RS01815
gene id: 1454201:NMS_RS01815
uniprot id: W8VZD4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1454201:NMS RS04695
gene id: 1454201:NMS_RS04695
uniprot id: W8VUX9
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1454201:NMS RS03790
gene id: 1454201:NMS_RS03790
uniprot id: W8VWJ3
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS06560
gene id: 1454201:NMS_RS06560
uniprot id: W8VVE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1454201:NMS RS11515
gene id: 1454201:NMS_RS11515
uniprot id: W8W0J2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1454201:NMS RS01085
gene id: 1454201:NMS_RS01085
uniprot id: W8VN50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1454201:NMS RS04450
gene id: 1454201:NMS_RS04450
uniprot id: W8VPA0
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS11735
gene id: 1454201:NMS_RS11735
uniprot id: W8VWM6
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1454201:NMS RS11710
gene id: 1454201:NMS_RS11710
uniprot id: W8VWM3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS08210
gene id: 1454201:NMS_RS08210
uniprot id: W8VXD1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1454201:NMS RS09140
gene id: 1454201:NMS_RS09140
uniprot id: W8VXH0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-53 and Arg-56) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1454201:NMS RS06430
gene id: 1454201:NMS_RS06430
uniprot id: W8VZX8
names: Similarity
messages: Belongs to the pirin family.

1454201:NMS RS11410
gene id: 1454201:NMS_RS11410
uniprot id: W8VXR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1454201:NMS RS01470
gene id: 1454201:NMS_RS01470
uniprot id: W8VZB9
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1454201:NMS RS11620
gene id: 1454201:NMS_RS11620
uniprot id: W8VRR9
names: Similarity
messages: Belongs to the DNA photolyase family.

1454201:NMS RS08780
gene id: 1454201:NMS_RS08780
uniprot id: W8VVX6
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS04370
gene id: 1454201:NMS_RS04370
uniprot id: W8VZN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1454201:NMS RS11835
gene id: 1454201:NMS_RS11835
uniprot id: W8VWN4
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1454201:NMS RS08725
gene id: 1454201:NMS_RS08725
uniprot id: W8VQQ3
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS08090
gene id: 1454201:NMS_RS08090
uniprot id: W8W046
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1454201:NMS RS02865
gene id: 1454201:NMS_RS02865
uniprot id: W8VPN8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1454201:NMS RS07390
gene id: 1454201:NMS_RS07390
uniprot id: W8VRA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1454201:NMS RS11285
gene id: 1454201:NMS_RS11285
uniprot id: W8VXR2
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1454201:NMS RS04675
gene id: 1454201:NMS_RS04675
uniprot id: W8VUX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1454201:NMS RS02145
gene id: 1454201:NMS_RS02145
uniprot id: W8VZE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1454201:NMS RS01865
gene id: 1454201:NMS_RS01865
uniprot id: W8VW30
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS00805
gene id: 1454201:NMS_RS00805
uniprot id: W8VVU5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Brp/Blh beta-carotene diooxygenase family.
messages: Catalyzes the cleavage of beta-carotene at its central double bond (15,15') to yield two molecules of all-trans-retinal.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS09710
gene id: 1454201:NMS_RS09710
uniprot id: W8VR18
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1454201:NMS RS07605
gene id: 1454201:NMS_RS07605
uniprot id: W8VXA4
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1454201:NMS RS03255
gene id: 1454201:NMS_RS03255
uniprot id: W8VWE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required for cell division and gliding motility.

1454201:NMS RS00590
gene id: 1454201:NMS_RS00590
uniprot id: W8VVR9
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1454201:NMS RS10675
gene id: 1454201:NMS_RS10675
uniprot id: W8VXN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1454201:NMS RS10705
gene id: 1454201:NMS_RS10705
uniprot id: W8VWE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1454201:NMS RS05375
gene id: 1454201:NMS_RS05375
uniprot id: W8VPM1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1454201:NMS RS01465
gene id: 1454201:NMS_RS01465
uniprot id: W8VP76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1454201:NMS RS07640
gene id: 1454201:NMS_RS07640
uniprot id: W8VQC2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1454201:NMS RS05495
gene id: 1454201:NMS_RS05495
uniprot id: W8VZT8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS03195
gene id: 1454201:NMS_RS03195
uniprot id: W8VNU7
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS01375
gene id: 1454201:NMS_RS01375
uniprot id: W8VVY9
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1454201:NMS RS08500
gene id: 1454201:NMS_RS08500
uniprot id: W8VVV0
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS11635
gene id: 1454201:NMS_RS11635
uniprot id: W8VWL7
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS07260
gene id: 1454201:NMS_RS07260
uniprot id: W8VX89
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1454201:NMS RS12530
gene id: 1454201:NMS_RS12530
uniprot id: W8W0N6
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS01835
gene id: 1454201:NMS_RS01835
uniprot id: W8VPB5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1454201:NMS RS11750
gene id: 1454201:NMS_RS11750
uniprot id: W8W0K2
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1454201:NMS RS10025
gene id: 1454201:NMS_RS10025
uniprot id: W8VW81
names: Similarity
messages: Belongs to the glutamate synthase family.

1454201:NMS RS00255
gene id: 1454201:NMS_RS00255
uniprot id: W8VVP6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1454201:NMS RS13315
gene id: 1454201:NMS_RS13315
uniprot id: W8VSC2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS07970
gene id: 1454201:NMS_RS07970
uniprot id: W8VRI3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1454201:NMS RS12655
gene id: 1454201:NMS_RS12655
uniprot id: W8VXX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1454201:NMS RS10260
gene id: 1454201:NMS_RS10260
uniprot id: W8VSD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1454201:NMS RS01200
gene id: 1454201:NMS_RS01200
uniprot id: W8VVX5
names: Similarity
messages: Belongs to the SusD family.

1454201:NMS RS00960
gene id: 1454201:NMS_RS00960
uniprot id: W8VN40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

1454201:NMS RS10820
gene id: 1454201:NMS_RS10820
uniprot id: W8W0G2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1454201:NMS RS11560
gene id: 1454201:NMS_RS11560
uniprot id: W8VXS4
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS02425
gene id: 1454201:NMS_RS02425
uniprot id: W8VW76
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

1454201:NMS RS06860
gene id: 1454201:NMS_RS06860
uniprot id: W8VVG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1454201:NMS RS05515
gene id: 1454201:NMS_RS05515
uniprot id: W8VQM3
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1454201:NMS RS08705
gene id: 1454201:NMS_RS08705
uniprot id: W8VRU3
names: Similarity
messages: Belongs to the SusD family.

1454201:NMS RS01515
gene id: 1454201:NMS_RS01515
uniprot id: W8VP80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1454201:NMS RS00070
gene id: 1454201:NMS_RS00070
uniprot id: W8VTU6
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1454201:NMS RS02185
gene id: 1454201:NMS_RS02185
uniprot id: W8VNH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1454201:NMS RS01140
gene id: 1454201:NMS_RS01140
uniprot id: W8VP44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1454201:NMS RS05840
gene id: 1454201:NMS_RS05840
uniprot id: W8VX23
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS06000
gene id: 1454201:NMS_RS06000
uniprot id: W8VQU7
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS02745
gene id: 1454201:NMS_RS02745
uniprot id: W8VZH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1454201:NMS RS03220
gene id: 1454201:NMS_RS03220
uniprot id: W8VNV8
names: Similarity
messages: Belongs to the SCO1/2 family.

1454201:NMS RS07005
gene id: 1454201:NMS_RS07005
uniprot id: W8VR57
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1454201:NMS RS13355
gene id: 1454201:NMS_RS13355
uniprot id: W8VN37
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS05590
gene id: 1454201:NMS_RS05590
uniprot id: W8VZU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADP/ATP translocase tlc family.
messages: Membrane

1454201:NMS RS01050
gene id: 1454201:NMS_RS01050
uniprot id: W8VU34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1454201:NMS RS01025
gene id: 1454201:NMS_RS01025
uniprot id: W8VU33
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1454201:NMS RS01355
gene id: 1454201:NMS_RS01355
uniprot id: W8VU49
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1454201:NMS RS02875
gene id: 1454201:NMS_RS02875
uniprot id: W8VWB0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1454201:NMS RS11295
gene id: 1454201:NMS_RS11295
uniprot id: W8VRN0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1454201:NMS RS12050
gene id: 1454201:NMS_RS12050
uniprot id: W8VSV2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1454201:NMS RS04100
gene id: 1454201:NMS_RS04100
uniprot id: W8VP58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1454201:NMS RS04175
gene id: 1454201:NMS_RS04175
uniprot id: W8VUS8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

1454201:NMS RS00790
gene id: 1454201:NMS_RS00790
uniprot id: W8VN19
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1454201:NMS RS12860
gene id: 1454201:NMS_RS12860
uniprot id: W8VXX9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1454201:NMS RS08145
gene id: 1454201:NMS_RS08145
uniprot id: W8VVS8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1454201:NMS RS10785
gene id: 1454201:NMS_RS10785
uniprot id: W8VRH9
names: Similarity
messages: Belongs to the RutC family.

1454201:NMS RS09240
gene id: 1454201:NMS_RS09240
uniprot id: W8VQW2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1454201:NMS RS10720
gene id: 1454201:NMS_RS10720
uniprot id: W8W0F8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1454201:NMS RS11390
gene id: 1454201:NMS_RS11390
uniprot id: W8VWJ4
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1454201:NMS RS02770
gene id: 1454201:NMS_RS02770
uniprot id: W8VZH3
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1454201:NMS RS13095
gene id: 1454201:NMS_RS13095
uniprot id: W8VT46
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1454201:NMS RS00780
gene id: 1454201:NMS_RS00780
uniprot id: W8VZ91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1454201:NMS RS08545
gene id: 1454201:NMS_RS08545
uniprot id: W8W065
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1454201:NMS RS02935
gene id: 1454201:NMS_RS02935
uniprot id: W8VNR4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS10965
gene id: 1454201:NMS_RS10965
uniprot id: W8W0G8
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1454201:NMS RS11035
gene id: 1454201:NMS_RS11035
uniprot id: W8W0H1
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1454201:NMS RS01585
gene id: 1454201:NMS_RS01585
uniprot id: W8VNA3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS12565
gene id: 1454201:NMS_RS12565
uniprot id: W8VWV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1454201:NMS RS12760
gene id: 1454201:NMS_RS12760
uniprot id: W8W0P5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1454201:NMS RS01545
gene id: 1454201:NMS_RS01545
uniprot id: W8VZC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1454201:NMS RS05420
gene id: 1454201:NMS_RS05420
uniprot id: W8VV51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1454201:NMS RS13360
gene id: 1454201:NMS_RS13360
uniprot id: W8VVV6
names: Similarity
messages: Belongs to the Skp family.

1454201:NMS RS01425
gene id: 1454201:NMS_RS01425
uniprot id: W8VVZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1454201:NMS RS09320
gene id: 1454201:NMS_RS09320
uniprot id: W8VS16
names: Similarity
messages: Belongs to the CsgA/CsgB family.

1454201:NMS RS07340
gene id: 1454201:NMS_RS07340
uniprot id: W8VQ88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1454201:NMS RS01560
gene id: 1454201:NMS_RS01560
uniprot id: W8VNA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1454201:NMS RS12040
gene id: 1454201:NMS_RS12040
uniprot id: W8W0L4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1454201:NMS RS01890
gene id: 1454201:NMS_RS01890
uniprot id: W8VW32
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1454201:NMS RS03440
gene id: 1454201:NMS_RS03440
uniprot id: W8VNZ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS06850
gene id: 1454201:NMS_RS06850
uniprot id: W8VZZ4
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS00160
gene id: 1454201:NMS_RS00160
uniprot id: W8VTV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1454201:NMS RS07425
gene id: 1454201:NMS_RS07425
uniprot id: W8VQ97
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1454201:NMS RS08160
gene id: 1454201:NMS_RS08160
uniprot id: W8W049
names: Similarity
messages: Belongs to the CinA family.

1454201:NMS RS08140
gene id: 1454201:NMS_RS08140
uniprot id: W8W048
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1454201:NMS RS06890
gene id: 1454201:NMS_RS06890
uniprot id: W8VQ42
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS01020
gene id: 1454201:NMS_RS01020
uniprot id: W8VVW2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1454201:NMS RS04985
gene id: 1454201:NMS_RS04985
uniprot id: W8VZR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1454201:NMS RS06690
gene id: 1454201:NMS_RS06690
uniprot id: W8VVF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1454201:NMS RS05320
gene id: 1454201:NMS_RS05320
uniprot id: W8VWW4
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1454201:NMS RS01580
gene id: 1454201:NMS_RS01580
uniprot id: W8VU63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1454201:NMS RS03670
gene id: 1454201:NMS_RS03670
uniprot id: W8VWI4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1454201:NMS RS05060
gene id: 1454201:NMS_RS05060
uniprot id: W8VPH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1454201:NMS RS01575
gene id: 1454201:NMS_RS01575
uniprot id: W8VW05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1454201:NMS RS08480
gene id: 1454201:NMS_RS08480
uniprot id: W8VQN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1454201:NMS RS04740
gene id: 1454201:NMS_RS04740
uniprot id: W8VPD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1454201:NMS RS10955
gene id: 1454201:NMS_RS10955
uniprot id: W8VRJ4
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1454201:NMS RS01605
gene id: 1454201:NMS_RS01605
uniprot id: W8VU65
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1454201:NMS RS01255
gene id: 1454201:NMS_RS01255
uniprot id: W8VU44
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1454201:NMS RS03230
gene id: 1454201:NMS_RS03230
uniprot id: W8VZJ2
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS07090
gene id: 1454201:NMS_RS07090
uniprot id: W8VVI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1454201:NMS RS07435
gene id: 1454201:NMS_RS07435
uniprot id: W8VRA6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1454201:NMS RS10540
gene id: 1454201:NMS_RS10540
uniprot id: W8VRF5
names: Similarity
messages: Belongs to the Fur family.

1454201:NMS RS03700
gene id: 1454201:NMS_RS03700
uniprot id: W8VUP5
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1454201:NMS RS02190
gene id: 1454201:NMS_RS02190
uniprot id: W8VPF7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1454201:NMS RS05245
gene id: 1454201:NMS_RS05245
uniprot id: W8VQH9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1454201:NMS RS10120
gene id: 1454201:NMS_RS10120
uniprot id: W8VR75
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1454201:NMS RS05825
gene id: 1454201:NMS_RS05825
uniprot id: W8VV86
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1454201:NMS RS03235
gene id: 1454201:NMS_RS03235
uniprot id: W8VWE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Membrane

1454201:NMS RS01635
gene id: 1454201:NMS_RS01635
uniprot id: W8VP94
names: Similarity
messages: Belongs to the NAD synthetase family.

1454201:NMS RS02480
gene id: 1454201:NMS_RS02480
uniprot id: W8VUE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1454201:NMS RS12405
gene id: 1454201:NMS_RS12405
uniprot id: W8VSY4
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS06565
gene id: 1454201:NMS_RS06565
uniprot id: W8VQ02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1454201:NMS RS06925
gene id: 1454201:NMS_RS06925
uniprot id: W8VZZ7
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS02040
gene id: 1454201:NMS_RS02040
uniprot id: W8VUA4
names: Similarity
messages: Belongs to the SusD family.

1454201:NMS RS12890
gene id: 1454201:NMS_RS12890
uniprot id: W8VS85
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

1454201:NMS RS01680
gene id: 1454201:NMS_RS01680
uniprot id: W8VW15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1454201:NMS RS04315
gene id: 1454201:NMS_RS04315
uniprot id: W8VWN3
names: Similarity
messages: Belongs to the SusD family.

1454201:NMS RS03850
gene id: 1454201:NMS_RS03850
uniprot id: W8VQ22
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1454201:NMS RS12470
gene id: 1454201:NMS_RS12470
uniprot id: W8VS29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1454201:NMS RS04575
gene id: 1454201:NMS_RS04575
uniprot id: W8VPB1
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1454201:NMS RS04720
gene id: 1454201:NMS_RS04720
uniprot id: W8VPC9
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

1454201:NMS RS07525
gene id: 1454201:NMS_RS07525
uniprot id: W8VQA6
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1454201:NMS RS05435
gene id: 1454201:NMS_RS05435
uniprot id: W8VWX3
names: Similarity
messages: Belongs to the cytochrome P450 family.

1454201:NMS RS06070
gene id: 1454201:NMS_RS06070
uniprot id: W8VX41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1454201:NMS RS07460
gene id: 1454201:NMS_RS07460
uniprot id: W8W018
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS06515
gene id: 1454201:NMS_RS06515
uniprot id: W8VVE1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1454201:NMS RS05160
gene id: 1454201:NMS_RS05160
uniprot id: W8VWV5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1454201:NMS RS08955
gene id: 1454201:NMS_RS08955
uniprot id: W8VVZ0
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1454201:NMS RS09950
gene id: 1454201:NMS_RS09950
uniprot id: W8VW75
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1454201:NMS RS06230
gene id: 1454201:NMS_RS06230
uniprot id: W8VVB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1454201:NMS RS08440
gene id: 1454201:NMS_RS08440
uniprot id: W8W061
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1454201:NMS RS12355
gene id: 1454201:NMS_RS12355
uniprot id: W8VSY0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

1454201:NMS RS05005
gene id: 1454201:NMS_RS05005
uniprot id: W8VQF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS07045
gene id: 1454201:NMS_RS07045
uniprot id: W8VQ59
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS09050
gene id: 1454201:NMS_RS09050
uniprot id: W8VXG6
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS00485
gene id: 1454201:NMS_RS00485
uniprot id: W8VZ79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

1454201:NMS RS12800
gene id: 1454201:NMS_RS12800
uniprot id: W8VT24
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1454201:NMS RS04665
gene id: 1454201:NMS_RS04665
uniprot id: W8VZQ2
names: Similarity
messages: Belongs to the pirin family.

1454201:NMS RS03800
gene id: 1454201:NMS_RS03800
uniprot id: W8VP23
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS02125
gene id: 1454201:NMS_RS02125
uniprot id: W8VUB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1454201:NMS RS10980
gene id: 1454201:NMS_RS10980
uniprot id: W8VRJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1454201:NMS RS03485
gene id: 1454201:NMS_RS03485
uniprot id: W8VNZ4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1454201:NMS RS05445
gene id: 1454201:NMS_RS05445
uniprot id: W8VQL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1454201:NMS RS05455
gene id: 1454201:NMS_RS05455
uniprot id: W8VWX6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1454201:NMS RS05810
gene id: 1454201:NMS_RS05810
uniprot id: W8VQS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1454201:NMS RS03685
gene id: 1454201:NMS_RS03685
uniprot id: W8VQ06
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1454201:NMS RS13205
gene id: 1454201:NMS_RS13205
uniprot id: W8VXZ3
names: Similarity
messages: Belongs to the peptidase M1 family.

1454201:NMS RS01920
gene id: 1454201:NMS_RS01920
uniprot id: W8VU94
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1454201:NMS RS04020
gene id: 1454201:NMS_RS04020
uniprot id: W8VWL1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1454201:NMS RS11890
gene id: 1454201:NMS_RS11890
uniprot id: W8VRV3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS02960
gene id: 1454201:NMS_RS02960
uniprot id: W8VNR7
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS06225
gene id: 1454201:NMS_RS06225
uniprot id: W8VZW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1454201:NMS RS02790
gene id: 1454201:NMS_RS02790
uniprot id: W8VPM9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1454201:NMS RS02545
gene id: 1454201:NMS_RS02545
uniprot id: W8VW86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1454201:NMS RS04895
gene id: 1454201:NMS_RS04895
uniprot id: W8VWT3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1454201:NMS RS02660
gene id: 1454201:NMS_RS02660
uniprot id: W8VNM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1454201:NMS RS03425
gene id: 1454201:NMS_RS03425
uniprot id: W8VZK0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1454201:NMS RS07135
gene id: 1454201:NMS_RS07135
uniprot id: W8VX84
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1454201:NMS RS06415
gene id: 1454201:NMS_RS06415
uniprot id: W8VVD5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS01115
gene id: 1454201:NMS_RS01115
uniprot id: W8VP41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1454201:NMS RS12620
gene id: 1454201:NMS_RS12620
uniprot id: W8VT03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1454201:NMS RS07000
gene id: 1454201:NMS_RS07000
uniprot id: W8VQ54
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1454201:NMS RS02155
gene id: 1454201:NMS_RS02155
uniprot id: W8VUB4
names: Similarity
messages: Belongs to the ribF family.

1454201:NMS RS12955
gene id: 1454201:NMS_RS12955
uniprot id: W8VXY3
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS03765
gene id: 1454201:NMS_RS03765
uniprot id: W8VWJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1454201:NMS RS13065
gene id: 1454201:NMS_RS13065
uniprot id: W8VSA1
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

1454201:NMS RS06270
gene id: 1454201:NMS_RS06270
uniprot id: W8VZX1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1454201:NMS RS02765
gene id: 1454201:NMS_RS02765
uniprot id: W8VPM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1454201:NMS RS03475
gene id: 1454201:NMS_RS03475
uniprot id: W8VZK2
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

1454201:NMS RS02640
gene id: 1454201:NMS_RS02640
uniprot id: W8VPL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

1454201:NMS RS02415
gene id: 1454201:NMS_RS02415
uniprot id: W8VPI3
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1454201:NMS RS08760
gene id: 1454201:NMS_RS08760
uniprot id: W8VVX3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1454201:NMS RS10910
gene id: 1454201:NMS_RS10910
uniprot id: W8VSK9
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS07200
gene id: 1454201:NMS_RS07200
uniprot id: W8VR78
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1454201:NMS RS03875
gene id: 1454201:NMS_RS03875
uniprot id: W8VQ24
names: Similarity
messages: Belongs to the peptidase S8 family.

1454201:NMS RS07080
gene id: 1454201:NMS_RS07080
uniprot id: W8W003
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1454201:NMS RS06350
gene id: 1454201:NMS_RS06350
uniprot id: W8VPY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

1454201:NMS RS12140
gene id: 1454201:NMS_RS12140
uniprot id: W8VRY7
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1454201:NMS RS08970
gene id: 1454201:NMS_RS08970
uniprot id: W8W083
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1454201:NMS RS09845
gene id: 1454201:NMS_RS09845
uniprot id: W8W0C0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1454201:NMS RS12250
gene id: 1454201:NMS_RS12250
uniprot id: W8VWS2
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1454201:NMS RS03845
gene id: 1454201:NMS_RS03845
uniprot id: W8VP28
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1454201:NMS RS02860
gene id: 1454201:NMS_RS02860
uniprot id: W8VNQ4
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS04775
gene id: 1454201:NMS_RS04775
uniprot id: W8VUY9
names: Similarity
messages: Belongs to the SCO1/2 family.

1454201:NMS RS08710
gene id: 1454201:NMS_RS08710
uniprot id: W8W072
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1454201:NMS RS04745
gene id: 1454201:NMS_RS04745
uniprot id: W8VQB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1454201:NMS RS09015
gene id: 1454201:NMS_RS09015
uniprot id: W8VRX9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1454201:NMS RS00970
gene id: 1454201:NMS_RS00970
uniprot id: W8VZ99
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1454201:NMS RS05945
gene id: 1454201:NMS_RS05945
uniprot id: W8VPU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MerT family.
messages: Cell inner membrane
messages: Membrane

1454201:NMS RS12925
gene id: 1454201:NMS_RS12925
uniprot id: W8W0Q2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1454201:NMS RS04540
gene id: 1454201:NMS_RS04540
uniprot id: W8VWQ2
names: Similarity
messages: Belongs to the SufE family.

1454201:NMS RS08590
gene id: 1454201:NMS_RS08590
uniprot id: W8VXE7
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1454201:NMS RS01700
gene id: 1454201:NMS_RS01700
uniprot id: W8VW16
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

1454201:NMS RS05295
gene id: 1454201:NMS_RS05295
uniprot id: W8VZS9
names: Similarity
messages: Belongs to the fabD family.

1454201:NMS RS00765
gene id: 1454201:NMS_RS00765
uniprot id: W8VU05
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1454201:NMS RS09185
gene id: 1454201:NMS_RS09185
uniprot id: W8VXH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1454201:NMS RS06315
gene id: 1454201:NMS_RS06315
uniprot id: W8VX53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1454201:NMS RS07155
gene id: 1454201:NMS_RS07155
uniprot id: W8W005
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1454201:NMS RS06950
gene id: 1454201:NMS_RS06950
uniprot id: W8VZZ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1454201:NMS RS09130
gene id: 1454201:NMS_RS09130
uniprot id: W8VRZ3
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1454201:NMS RS03435
gene id: 1454201:NMS_RS03435
uniprot id: W8VUM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS06835
gene id: 1454201:NMS_RS06835
uniprot id: W8VVG6
names: Similarity
messages: Belongs to the MreC family.

1454201:NMS RS01065
gene id: 1454201:NMS_RS01065
uniprot id: W8VP36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1454201:NMS RS10995
gene id: 1454201:NMS_RS10995
uniprot id: W8VWF9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1454201:NMS RS12855
gene id: 1454201:NMS_RS12855
uniprot id: W8W0P9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1454201:NMS RS08455
gene id: 1454201:NMS_RS08455
uniprot id: W8VQN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1454201:NMS RS06245
gene id: 1454201:NMS_RS06245
uniprot id: W8VZX0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1454201:NMS RS11075
gene id: 1454201:NMS_RS11075
uniprot id: W8VRK4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1454201:NMS RS09125
gene id: 1454201:NMS_RS09125
uniprot id: W8VQU8
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

1454201:NMS RS11930
gene id: 1454201:NMS_RS11930
uniprot id: W8VWP3
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1454201:NMS RS12465
gene id: 1454201:NMS_RS12465
uniprot id: W8VXW3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1454201:NMS RS10730
gene id: 1454201:NMS_RS10730
uniprot id: W8VWE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1454201:NMS RS11025
gene id: 1454201:NMS_RS11025
uniprot id: W8VRK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1454201:NMS RS01435
gene id: 1454201:NMS_RS01435
uniprot id: W8VN85
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1454201:NMS RS01185
gene id: 1454201:NMS_RS01185
uniprot id: W8VN57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1454201:NMS RS02510
gene id: 1454201:NMS_RS02510
uniprot id: W8VZG3
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS13460
gene id: 1454201:NMS_RS13460
uniprot id: W8VVH0
names: Similarity
messages: Belongs to the peptidase C40 family.

1454201:NMS RS00115
gene id: 1454201:NMS_RS00115
uniprot id: W8VMS8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1454201:NMS RS03025
gene id: 1454201:NMS_RS03025
uniprot id: W8VPQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1454201:NMS RS07860
gene id: 1454201:NMS_RS07860
uniprot id: W8W035
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1454201:NMS RS04470
gene id: 1454201:NMS_RS04470
uniprot id: W8VUV5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1454201:NMS RS09970
gene id: 1454201:NMS_RS09970
uniprot id: W8VXK5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1454201:NMS RS10085
gene id: 1454201:NMS_RS10085
uniprot id: W8VSA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1454201:NMS RS00860
gene id: 1454201:NMS_RS00860
uniprot id: W8VN30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

1454201:NMS RS00800
gene id: 1454201:NMS_RS00800
uniprot id: W8VZ92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

1454201:NMS RS00290
gene id: 1454201:NMS_RS00290
uniprot id: W8VTW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1454201:NMS RS02160
gene id: 1454201:NMS_RS02160
uniprot id: W8VNG8
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS03645
gene id: 1454201:NMS_RS03645
uniprot id: W8VZK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1454201:NMS RS08875
gene id: 1454201:NMS_RS08875
uniprot id: W8VXF9
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS04510
gene id: 1454201:NMS_RS04510
uniprot id: W8VZP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1454201:NMS RS11800
gene id: 1454201:NMS_RS11800
uniprot id: W8VST1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1454201:NMS RS07145
gene id: 1454201:NMS_RS07145
uniprot id: W8VQ69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1454201:NMS RS07235
gene id: 1454201:NMS_RS07235
uniprot id: W8VX88
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1454201:NMS RS02470
gene id: 1454201:NMS_RS02470
uniprot id: W8VZG1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1454201:NMS RS07820
gene id: 1454201:NMS_RS07820
uniprot id: W8VVP3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1454201:NMS RS06410
gene id: 1454201:NMS_RS06410
uniprot id: W8VX57
names: Function
names: Similarity
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.

1454201:NMS RS11170
gene id: 1454201:NMS_RS11170
uniprot id: W8W0H7
names: Similarity
messages: Belongs to the peptidase M13 family.

1454201:NMS RS03825
gene id: 1454201:NMS_RS03825
uniprot id: W8VP25
names: Similarity
messages: Belongs to the peptidase S9A family.

1454201:NMS RS11530
gene id: 1454201:NMS_RS11530
uniprot id: W8VSQ9
names: Similarity
messages: Belongs to the Dps family.

1454201:NMS RS03805
gene id: 1454201:NMS_RS03805
uniprot id: W8VQ17
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1454201:NMS RS10695
gene id: 1454201:NMS_RS10695
uniprot id: W8W0F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1454201:NMS RS07185
gene id: 1454201:NMS_RS07185
uniprot id: W8VX86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1454201:NMS RS01715
gene id: 1454201:NMS_RS01715
uniprot id: W8VPA6
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1454201:NMS RS07850
gene id: 1454201:NMS_RS07850
uniprot id: W8VQF2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1454201:NMS RS07015
gene id: 1454201:NMS_RS07015
uniprot id: W8VVI0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1454201:NMS RS01440
gene id: 1454201:NMS_RS01440
uniprot id: W8VP73
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1454201:NMS RS10855
gene id: 1454201:NMS_RS10855
uniprot id: W8VWE8
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS04935
gene id: 1454201:NMS_RS04935
uniprot id: W8VQE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1454201:NMS RS10830
gene id: 1454201:NMS_RS10830
uniprot id: W8VWE7
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1454201:NMS RS07020
gene id: 1454201:NMS_RS07020
uniprot id: W8VQ57
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS10535
gene id: 1454201:NMS_RS10535
uniprot id: W8VWD3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1454201:NMS RS08080
gene id: 1454201:NMS_RS08080
uniprot id: W8VQJ3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1454201:NMS RS03920
gene id: 1454201:NMS_RS03920
uniprot id: W8VP39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1454201:NMS RS03270
gene id: 1454201:NMS_RS03270
uniprot id: W8VPV9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1454201:NMS RS01390
gene id: 1454201:NMS_RS01390
uniprot id: W8VP69
names: Similarity
messages: Belongs to the asparagine synthetase family.

1454201:NMS RS08485
gene id: 1454201:NMS_RS08485
uniprot id: W8VRR8
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1454201:NMS RS13220
gene id: 1454201:NMS_RS13220
uniprot id: W8VT56
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1454201:NMS RS08610
gene id: 1454201:NMS_RS08610
uniprot id: W8W068
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1454201:NMS RS07650
gene id: 1454201:NMS_RS07650
uniprot id: W8W026
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1454201:NMS RS01460
gene id: 1454201:NMS_RS01460
uniprot id: W8VN88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1454201:NMS RS03815
gene id: 1454201:NMS_RS03815
uniprot id: W8VWJ5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS01075
gene id: 1454201:NMS_RS01075
uniprot id: W8VVW6
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1454201:NMS RS05280
gene id: 1454201:NMS_RS05280
uniprot id: W8VWW2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1454201:NMS RS06590
gene id: 1454201:NMS_RS06590
uniprot id: W8VQ05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1454201:NMS RS12730
gene id: 1454201:NMS_RS12730
uniprot id: W8VT18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1454201:NMS RS02440
gene id: 1454201:NMS_RS02440
uniprot id: W8VZG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1454201:NMS RS09460
gene id: 1454201:NMS_RS09460
uniprot id: W8W0A4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1454201:NMS RS00465
gene id: 1454201:NMS_RS00465
uniprot id: W8VZ78
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1454201:NMS RS00460
gene id: 1454201:NMS_RS00460
uniprot id: W8VNV4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1454201:NMS RS03935
gene id: 1454201:NMS_RS03935
uniprot id: W8VZM1
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1454201:NMS RS05490
gene id: 1454201:NMS_RS05490
uniprot id: W8VQL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1454201:NMS RS12700
gene id: 1454201:NMS_RS12700
uniprot id: W8VS64
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1454201:NMS RS07480
gene id: 1454201:NMS_RS07480
uniprot id: W8VRB1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1454201:NMS RS01195
gene id: 1454201:NMS_RS01195
uniprot id: W8VZA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1454201:NMS RS10300
gene id: 1454201:NMS_RS10300
uniprot id: W8VRA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1454201:NMS RS06005
gene id: 1454201:NMS_RS06005
uniprot id: W8VZV9
names: Similarity
messages: Belongs to the DtxR/MntR family.

1454201:NMS RS04085
gene id: 1454201:NMS_RS04085
uniprot id: W8VZM7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1454201:NMS RS01295
gene id: 1454201:NMS_RS01295
uniprot id: W8VZB2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1454201:NMS RS12045
gene id: 1454201:NMS_RS12045
uniprot id: W8VWQ3
names: Similarity
messages: Belongs to the threonine aldolase family.

1454201:NMS RS01490
gene id: 1454201:NMS_RS01490
uniprot id: W8VP78
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

1454201:NMS RS03300
gene id: 1454201:NMS_RS03300
uniprot id: W8VZJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1454201:NMS RS09030
gene id: 1454201:NMS_RS09030
uniprot id: W8VVZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1454201:NMS RS01335
gene id: 1454201:NMS_RS01335
uniprot id: W8VN73
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1454201:NMS RS11270
gene id: 1454201:NMS_RS11270
uniprot id: W8VWI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1454201:NMS RS12415
gene id: 1454201:NMS_RS12415
uniprot id: W8VXW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1454201:NMS RS07365
gene id: 1454201:NMS_RS07365
uniprot id: W8VQ90
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS13325
gene id: 1454201:NMS_RS13325
uniprot id: W8VNR5
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS11020
gene id: 1454201:NMS_RS11020
uniprot id: W8VWG0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1454201:NMS RS12540
gene id: 1454201:NMS_RS12540
uniprot id: W8VWU8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS07875
gene id: 1454201:NMS_RS07875
uniprot id: W8VQF5
names: Similarity
messages: Belongs to the type IB topoisomerase family.

1454201:NMS RS05365
gene id: 1454201:NMS_RS05365
uniprot id: W8VWW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1454201:NMS RS03940
gene id: 1454201:NMS_RS03940
uniprot id: W8VWK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1454201:NMS RS09010
gene id: 1454201:NMS_RS09010
uniprot id: W8VQT4
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1454201:NMS RS11895
gene id: 1454201:NMS_RS11895
uniprot id: W8W0K8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1454201:NMS RS01080
gene id: 1454201:NMS_RS01080
uniprot id: W8VU36
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1454201:NMS RS03200
gene id: 1454201:NMS_RS03200
uniprot id: W8VPT3
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS01060
gene id: 1454201:NMS_RS01060
uniprot id: W8VN49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1454201:NMS RS06675
gene id: 1454201:NMS_RS06675
uniprot id: W8VR20
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1454201:NMS RS04465
gene id: 1454201:NMS_RS04465
uniprot id: W8VWP6
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

1454201:NMS RS09605
gene id: 1454201:NMS_RS09605
uniprot id: W8W0B0
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1454201:NMS RS01240
gene id: 1454201:NMS_RS01240
uniprot id: W8VP54
names: Similarity
messages: Belongs to the UPF0246 family.

1454201:NMS RS06910
gene id: 1454201:NMS_RS06910
uniprot id: W8VVH2
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1454201:NMS RS01430
gene id: 1454201:NMS_RS01430
uniprot id: W8VU52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1454201:NMS RS11500
gene id: 1454201:NMS_RS11500
uniprot id: W8VWK4
names: Similarity
messages: Belongs to the ParB family.

1454201:NMS RS03775
gene id: 1454201:NMS_RS03775
uniprot id: W8VP20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1454201:NMS RS11700
gene id: 1454201:NMS_RS11700
uniprot id: W8W0K0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1454201:NMS RS02495
gene id: 1454201:NMS_RS02495
uniprot id: W8VW82
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS11440
gene id: 1454201:NMS_RS11440
uniprot id: W8VSQ2
names: Similarity
messages: Belongs to the peptidase M16 family.

1454201:NMS RS08260
gene id: 1454201:NMS_RS08260
uniprot id: W8VVT6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1454201:NMS RS02200
gene id: 1454201:NMS_RS02200
uniprot id: W8VW58
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1454201:NMS RS03345
gene id: 1454201:NMS_RS03345
uniprot id: W8VPW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1454201:NMS RS02225
gene id: 1454201:NMS_RS02225
uniprot id: W8VW60
names: Similarity
messages: Belongs to the aspartokinase family.

1454201:NMS RS03505
gene id: 1454201:NMS_RS03505
uniprot id: W8VUN2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1454201:NMS RS06035
gene id: 1454201:NMS_RS06035
uniprot id: W8VQV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1454201:NMS RS03915
gene id: 1454201:NMS_RS03915
uniprot id: W8VUQ7
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS04735
gene id: 1454201:NMS_RS04735
uniprot id: W8VUY4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1454201:NMS RS00245
gene id: 1454201:NMS_RS00245
uniprot id: W8VNT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1454201:NMS RS07635
gene id: 1454201:NMS_RS07635
uniprot id: W8VVM7
names: Similarity
messages: Belongs to the stealth family.

1454201:NMS RS10865
gene id: 1454201:NMS_RS10865
uniprot id: W8W0G4
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1454201:NMS RS04555
gene id: 1454201:NMS_RS04555
uniprot id: W8VQ93
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1454201:NMS RS12270
gene id: 1454201:NMS_RS12270
uniprot id: W8VS03
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1454201:NMS RS12170
gene id: 1454201:NMS_RS12170
uniprot id: W8VSW1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1454201:NMS RS02500
gene id: 1454201:NMS_RS02500
uniprot id: W8VUE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1454201:NMS RS01720
gene id: 1454201:NMS_RS01720
uniprot id: W8VZD0
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

1454201:NMS RS09580
gene id: 1454201:NMS_RS09580
uniprot id: W8W0A9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1454201:NMS RS06340
gene id: 1454201:NMS_RS06340
uniprot id: W8VX54
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

1454201:NMS RS06425
gene id: 1454201:NMS_RS06425
uniprot id: W8VQZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

1454201:NMS RS07395
gene id: 1454201:NMS_RS07395
uniprot id: W8VX95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1454201:NMS RS01105
gene id: 1454201:NMS_RS01105
uniprot id: W8VU38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1454201:NMS RS06870
gene id: 1454201:NMS_RS06870
uniprot id: W8VR42
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1454201:NMS RS04560
gene id: 1454201:NMS_RS04560
uniprot id: W8VZP7
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1454201:NMS RS04360
gene id: 1454201:NMS_RS04360
uniprot id: W8VWN7
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS03275
gene id: 1454201:NMS_RS03275
uniprot id: W8VZJ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1454201:NMS RS03925
gene id: 1454201:NMS_RS03925
uniprot id: W8VQ29
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1454201:NMS RS01215
gene id: 1454201:NMS_RS01215
uniprot id: W8VP52
names: Subcellular Location Annotation
messages: Membrane

1454201:NMS RS10775
gene id: 1454201:NMS_RS10775
uniprot id: W8VXP0
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1454201:NMS RS02585
gene id: 1454201:NMS_RS02585
uniprot id: W8VPK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1454201:NMS RS12385
gene id: 1454201:NMS_RS12385
uniprot id: W8W0N0
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1454201:NMS RS03240
gene id: 1454201:NMS_RS03240
uniprot id: W8VUL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1454201:NMS RS12155
gene id: 1454201:NMS_RS12155
uniprot id: W8VXU9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1454201:NMS RS08465
gene id: 1454201:NMS_RS08465
uniprot id: W8W062
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1454201:NMS RS08105
gene id: 1454201:NMS_RS08105
uniprot id: W8VQJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1454201:NMS RS13305
gene id: 1454201:NMS_RS13305
uniprot id: W8VXZ7
names: Similarity
messages: Belongs to the BshC family.

1454201:NMS RS03690
gene id: 1454201:NMS_RS03690
uniprot id: W8VZL1
names: Similarity
messages: Belongs to the DprA/Smf family.

1454201:NMS RS01290
gene id: 1454201:NMS_RS01290
uniprot id: W8VP60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1454201:NMS RS13330
gene id: 1454201:NMS_RS13330
uniprot id: W8VMV3
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1454201:NMS RS10485
gene id: 1454201:NMS_RS10485
uniprot id: W8VWD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane