1448857:CCORG RS02005
gene id: 1448857:CCORG_RS02005
uniprot id: A0A7M1LJ48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1448857:CCORG RS07775
gene id: 1448857:CCORG_RS07775
uniprot id: A0A7M1LHH5
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1448857:CCORG RS08520
gene id: 1448857:CCORG_RS08520
uniprot id: A0A7M1LHV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1448857:CCORG RS04850
gene id: 1448857:CCORG_RS04850
uniprot id: A0A7M1LFA9
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1448857:CCORG RS01575
gene id: 1448857:CCORG_RS01575
uniprot id: A0A7M1LG90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1448857:CCORG RS04980
gene id: 1448857:CCORG_RS04980
uniprot id: A0A7M1LHM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1448857:CCORG RS02950
gene id: 1448857:CCORG_RS02950
uniprot id: A0A7M1LFL4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1448857:CCORG RS05420
gene id: 1448857:CCORG_RS05420
uniprot id: A0A7M1LFR2
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1448857:CCORG RS04540
gene id: 1448857:CCORG_RS04540
uniprot id: A0A7M1LF73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1448857:CCORG RS00175
gene id: 1448857:CCORG_RS00175
uniprot id: A0A7M1LHQ9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1448857:CCORG RS00065
gene id: 1448857:CCORG_RS00065
uniprot id: A0A7M1LH06
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1448857:CCORG RS05535
gene id: 1448857:CCORG_RS05535
uniprot id: A0A7M1LHB9
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1448857:CCORG RS01930
gene id: 1448857:CCORG_RS01930
uniprot id: A0A7M1LJ59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1448857:CCORG RS07460
gene id: 1448857:CCORG_RS07460
uniprot id: A0A7M1LDZ8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1448857:CCORG RS02160
gene id: 1448857:CCORG_RS02160
uniprot id: A0A7M1LG01
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS07540
gene id: 1448857:CCORG_RS07540
uniprot id: A0A7M1LJJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Hydrolyzes 6-aminopenicillinic acid and 7-aminocephalosporanic acid (ACA) derivatives.
messages: Secreted

1448857:CCORG RS05930
gene id: 1448857:CCORG_RS05930
uniprot id: A0A7M1LEQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1448857:CCORG RS01695
gene id: 1448857:CCORG_RS01695
uniprot id: A0A7M1LJ92
names: Function
names: Similarity
messages: Belongs to the phage GPA family.
messages: Possible endonuclease which induces a single-strand cut and initiates DNA replication.

1448857:CCORG RS06960
gene id: 1448857:CCORG_RS06960
uniprot id: A0A7M1LDJ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS05635
gene id: 1448857:CCORG_RS05635
uniprot id: A0A7M1LG61
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1448857:CCORG RS06600
gene id: 1448857:CCORG_RS06600
uniprot id: A0A7M1LGT5
names: Similarity
messages: Belongs to the IMPACT family.

1448857:CCORG RS01515
gene id: 1448857:CCORG_RS01515
uniprot id: A0A7M1LGP9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1448857:CCORG RS01020
gene id: 1448857:CCORG_RS01020
uniprot id: A0A7M1LIB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1448857:CCORG RS02915
gene id: 1448857:CCORG_RS02915
uniprot id: A0A7M1LGA8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1448857:CCORG RS04255
gene id: 1448857:CCORG_RS04255
uniprot id: A0A7M1LI13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1448857:CCORG RS08240
gene id: 1448857:CCORG_RS08240
uniprot id: A0A7M1LH92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1448857:CCORG RS02590
gene id: 1448857:CCORG_RS02590
uniprot id: A0A7M1LFU8
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1448857:CCORG RS05145
gene id: 1448857:CCORG_RS05145
uniprot id: A0A7M1LHJ2
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1448857:CCORG RS04575
gene id: 1448857:CCORG_RS04575
uniprot id: A0A7M1LFI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1448857:CCORG RS04620
gene id: 1448857:CCORG_RS04620
uniprot id: A0A7M1LHT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1448857:CCORG RS07235
gene id: 1448857:CCORG_RS07235
uniprot id: A0A7M1LDH4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1448857:CCORG RS07850
gene id: 1448857:CCORG_RS07850
uniprot id: A0A7M1LHJ1
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1448857:CCORG RS00460
gene id: 1448857:CCORG_RS00460
uniprot id: A0A7M1LHK8
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1448857:CCORG RS04355
gene id: 1448857:CCORG_RS04355
uniprot id: A0A7M1LEX0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1448857:CCORG RS04645
gene id: 1448857:CCORG_RS04645
uniprot id: A0A7M1LF50
names: Function
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.

1448857:CCORG RS04615
gene id: 1448857:CCORG_RS04615
uniprot id: A0A7M1LGT6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1448857:CCORG RS01835
gene id: 1448857:CCORG_RS01835
uniprot id: A0A7M1LG47
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1448857:CCORG RS06635
gene id: 1448857:CCORG_RS06635
uniprot id: A0A7M1LDS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1448857:CCORG RS08505
gene id: 1448857:CCORG_RS08505
uniprot id: A0A7M1LIZ7
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1448857:CCORG RS04235
gene id: 1448857:CCORG_RS04235
uniprot id: A0A7M1LEZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1448857:CCORG RS06575
gene id: 1448857:CCORG_RS06575
uniprot id: A0A7M1LE21
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1448857:CCORG RS00675
gene id: 1448857:CCORG_RS00675
uniprot id: A0A7M1LJS0
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1448857:CCORG RS00540
gene id: 1448857:CCORG_RS00540
uniprot id: A0A7M1LHJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1448857:CCORG RS08025
gene id: 1448857:CCORG_RS08025
uniprot id: A0A7M1LJX8
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS00945
gene id: 1448857:CCORG_RS00945
uniprot id: A0A7M1LGP3
names: Similarity
messages: Belongs to the GSP E family.

1448857:CCORG RS00890
gene id: 1448857:CCORG_RS00890
uniprot id: A0A7M1LGM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1448857:CCORG RS04700
gene id: 1448857:CCORG_RS04700
uniprot id: A0A7M1LF43
names: Similarity
messages: Belongs to the AAA ATPase family.

1448857:CCORG RS07635
gene id: 1448857:CCORG_RS07635
uniprot id: A0A7M1LIA1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS00910
gene id: 1448857:CCORG_RS00910
uniprot id: A0A7M1LIE6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1448857:CCORG RS03810
gene id: 1448857:CCORG_RS03810
uniprot id: A0A7M1LGQ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS08090
gene id: 1448857:CCORG_RS08090
uniprot id: A0A7M1LHF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1448857:CCORG RS07905
gene id: 1448857:CCORG_RS07905
uniprot id: A0A7M1LHF7
names: Caution
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS03390
gene id: 1448857:CCORG_RS03390
uniprot id: A0A7M1LHG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1448857:CCORG RS07475
gene id: 1448857:CCORG_RS07475
uniprot id: A0A7M1LJW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

1448857:CCORG RS08115
gene id: 1448857:CCORG_RS08115
uniprot id: A0A7M1LHY9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1448857:CCORG RS00230
gene id: 1448857:CCORG_RS00230
uniprot id: A0A7M1LGX7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1448857:CCORG RS07115
gene id: 1448857:CCORG_RS07115
uniprot id: A0A7M1LDH5
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1448857:CCORG RS00985
gene id: 1448857:CCORG_RS00985
uniprot id: A0A7M1LHB7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1448857:CCORG RS06865
gene id: 1448857:CCORG_RS06865
uniprot id: A0A7M1LGN7
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS01620
gene id: 1448857:CCORG_RS01620
uniprot id: A0A7M1LGA5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1448857:CCORG RS00585
gene id: 1448857:CCORG_RS00585
uniprot id: A0A7M1LHH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1448857:CCORG RS06565
gene id: 1448857:CCORG_RS06565
uniprot id: A0A7M1LDQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Dps family.
messages: Cytoplasm

1448857:CCORG RS08035
gene id: 1448857:CCORG_RS08035
uniprot id: A0A7M1LHF9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1448857:CCORG RS01580
gene id: 1448857:CCORG_RS01580
uniprot id: A0A7M1LIA8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS06365
gene id: 1448857:CCORG_RS06365
uniprot id: A0A7M1LF99
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1448857:CCORG RS00015
gene id: 1448857:CCORG_RS00015
uniprot id: A0A7M1LHH4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1448857:CCORG RS04300
gene id: 1448857:CCORG_RS04300
uniprot id: A0A7M1LEY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1448857:CCORG RS03730
gene id: 1448857:CCORG_RS03730
uniprot id: A0A7M1LF68
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1448857:CCORG RS02035
gene id: 1448857:CCORG_RS02035
uniprot id: A0A7M1LG07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1448857:CCORG RS04335
gene id: 1448857:CCORG_RS04335
uniprot id: A0A7M1LFM2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS01315
gene id: 1448857:CCORG_RS01315
uniprot id: A0A7M1LGE0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1448857:CCORG RS08295
gene id: 1448857:CCORG_RS08295
uniprot id: A0A7M1LHZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1448857:CCORG RS05195
gene id: 1448857:CCORG_RS05195
uniprot id: A0A7M1LGF5
names: Function
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1448857:CCORG RS02700
gene id: 1448857:CCORG_RS02700
uniprot id: A0A7M1LHR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1448857:CCORG RS04475
gene id: 1448857:CCORG_RS04475
uniprot id: A0A7M1LFK5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1448857:CCORG RS08475
gene id: 1448857:CCORG_RS08475
uniprot id: A0A7M1LHK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1448857:CCORG RS02800
gene id: 1448857:CCORG_RS02800
uniprot id: A0A7M1LHQ1
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS04855
gene id: 1448857:CCORG_RS04855
uniprot id: A0A7M1LF03
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

1448857:CCORG RS00650
gene id: 1448857:CCORG_RS00650
uniprot id: A0A7M1LH61
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1448857:CCORG RS07455
gene id: 1448857:CCORG_RS07455
uniprot id: A0A7M1LDC5
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

1448857:CCORG RS03225
gene id: 1448857:CCORG_RS03225
uniprot id: A0A7M1LG65
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1448857:CCORG RS08085
gene id: 1448857:CCORG_RS08085
uniprot id: A0A7M1LHB3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1448857:CCORG RS00595
gene id: 1448857:CCORG_RS00595
uniprot id: A0A7M1LHI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1448857:CCORG RS01110
gene id: 1448857:CCORG_RS01110
uniprot id: A0A7M1LGH5
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1448857:CCORG RS07415
gene id: 1448857:CCORG_RS07415
uniprot id: A0A7M1LDM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

1448857:CCORG RS02470
gene id: 1448857:CCORG_RS02470
uniprot id: A0A7M1LFS5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS00365
gene id: 1448857:CCORG_RS00365
uniprot id: A0A7M1LGZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1448857:CCORG RS01625
gene id: 1448857:CCORG_RS01625
uniprot id: A0A7M1LG81
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1448857:CCORG RS04755
gene id: 1448857:CCORG_RS04755
uniprot id: A0A7M1LEN8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1448857:CCORG RS05690
gene id: 1448857:CCORG_RS05690
uniprot id: A0A7M1LH88
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1448857:CCORG RS06135
gene id: 1448857:CCORG_RS06135
uniprot id: A0A7M1LFE8
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1448857:CCORG RS04950
gene id: 1448857:CCORG_RS04950
uniprot id: A0A7M1LF87
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1448857:CCORG RS00225
gene id: 1448857:CCORG_RS00225
uniprot id: A0A7M1LHM8
names: Function
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1448857:CCORG RS04840
gene id: 1448857:CCORG_RS04840
uniprot id: A0A7M1LFC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1448857:CCORG RS02670
gene id: 1448857:CCORG_RS02670
uniprot id: A0A7M1LFN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1448857:CCORG RS03885
gene id: 1448857:CCORG_RS03885
uniprot id: A0A7M1LFK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1448857:CCORG RS07570
gene id: 1448857:CCORG_RS07570
uniprot id: A0A7M1LHL2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1448857:CCORG RS07610
gene id: 1448857:CCORG_RS07610
uniprot id: A0A7M1LHK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1448857:CCORG RS02120
gene id: 1448857:CCORG_RS02120
uniprot id: A0A7M1LJ29
names: Similarity
messages: Belongs to the cytochrome c-552 family.

1448857:CCORG RS07215
gene id: 1448857:CCORG_RS07215
uniprot id: A0A7M1LDF9
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1448857:CCORG RS02060
gene id: 1448857:CCORG_RS02060
uniprot id: A0A7M1LI25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1448857:CCORG RS07495
gene id: 1448857:CCORG_RS07495
uniprot id: A0A7M1LHM7
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS01550
gene id: 1448857:CCORG_RS01550
uniprot id: A0A7M1LG94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1448857:CCORG RS01510
gene id: 1448857:CCORG_RS01510
uniprot id: A0A7M1LH20
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1448857:CCORG RS04725
gene id: 1448857:CCORG_RS04725
uniprot id: A0A7M1LHS0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1448857:CCORG RS03400
gene id: 1448857:CCORG_RS03400
uniprot id: A0A7M1LGX6
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS04070
gene id: 1448857:CCORG_RS04070
uniprot id: A0A7M1LF39
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1448857:CCORG RS05540
gene id: 1448857:CCORG_RS05540
uniprot id: A0A7M1LFP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1448857:CCORG RS04730
gene id: 1448857:CCORG_RS04730
uniprot id: A0A7M1LG70
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1448857:CCORG RS05605
gene id: 1448857:CCORG_RS05605
uniprot id: A0A7M1LE71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1448857:CCORG RS00625
gene id: 1448857:CCORG_RS00625
uniprot id: A0A7M1LJS9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1448857:CCORG RS01085
gene id: 1448857:CCORG_RS01085
uniprot id: A0A7M1LGH7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1448857:CCORG RS04435
gene id: 1448857:CCORG_RS04435
uniprot id: A0A7M1LFJ8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1448857:CCORG RS08320
gene id: 1448857:CCORG_RS08320
uniprot id: A0A7M1LJE7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1448857:CCORG RS07625
gene id: 1448857:CCORG_RS07625
uniprot id: A0A7M1LHK1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1448857:CCORG RS07815
gene id: 1448857:CCORG_RS07815
uniprot id: A0A7M1LJD8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1448857:CCORG RS08195
gene id: 1448857:CCORG_RS08195
uniprot id: A0A7M1LI16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1448857:CCORG RS07090
gene id: 1448857:CCORG_RS07090
uniprot id: A0A7M1LDI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1448857:CCORG RS02210
gene id: 1448857:CCORG_RS02210
uniprot id: A0A7M1LFX7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS01540
gene id: 1448857:CCORG_RS01540
uniprot id: A0A7M1LI07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1448857:CCORG RS02545
gene id: 1448857:CCORG_RS02545
uniprot id: A0A7M1LHT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1448857:CCORG RS08345
gene id: 1448857:CCORG_RS08345
uniprot id: A0A7M1LH66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1448857:CCORG RS04280
gene id: 1448857:CCORG_RS04280
uniprot id: A0A7M1LFP6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1448857:CCORG RS07000
gene id: 1448857:CCORG_RS07000
uniprot id: A0A7M1LE74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1448857:CCORG RS05005
gene id: 1448857:CCORG_RS05005
uniprot id: A0A7M1LEX2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1448857:CCORG RS05165
gene id: 1448857:CCORG_RS05165
uniprot id: A0A7M1LEF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

1448857:CCORG RS08250
gene id: 1448857:CCORG_RS08250
uniprot id: A0A7M1LHP7
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1448857:CCORG RS07490
gene id: 1448857:CCORG_RS07490
uniprot id: A0A7M1LIA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

1448857:CCORG RS05310
gene id: 1448857:CCORG_RS05310
uniprot id: A0A7M1LF25
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS04990
gene id: 1448857:CCORG_RS04990
uniprot id: A0A7M1LF90
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS00120
gene id: 1448857:CCORG_RS00120
uniprot id: A0A7M1LHR7
names: Similarity
messages: Belongs to the asparaginase 1 family.

1448857:CCORG RS07030
gene id: 1448857:CCORG_RS07030
uniprot id: A0A7M1LDJ2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1448857:CCORG RS06735
gene id: 1448857:CCORG_RS06735
uniprot id: A0A7M1LDR0
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1448857:CCORG RS00565
gene id: 1448857:CCORG_RS00565
uniprot id: A0A7M1LIX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1448857:CCORG RS06785
gene id: 1448857:CCORG_RS06785
uniprot id: A0A7M1LDM1
names: Similarity
messages: Belongs to the GSP E family.

1448857:CCORG RS04580
gene id: 1448857:CCORG_RS04580
uniprot id: A0A7M1LER7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

1448857:CCORG RS06345
gene id: 1448857:CCORG_RS06345
uniprot id: A0A7M1LDX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1448857:CCORG RS07085
gene id: 1448857:CCORG_RS07085
uniprot id: A0A7M1LDK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1448857:CCORG RS03130
gene id: 1448857:CCORG_RS03130
uniprot id: A0A7M1LFL3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1448857:CCORG RS01250
gene id: 1448857:CCORG_RS01250
uniprot id: A0A7M1LH67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1448857:CCORG RS00975
gene id: 1448857:CCORG_RS00975
uniprot id: A0A7M1LHA0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1448857:CCORG RS00185
gene id: 1448857:CCORG_RS00185
uniprot id: A0A7M1LGY3
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1448857:CCORG RS00245
gene id: 1448857:CCORG_RS00245
uniprot id: A0A7M1LGW9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1448857:CCORG RS00740
gene id: 1448857:CCORG_RS00740
uniprot id: A0A7M1LHE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1448857:CCORG RS01525
gene id: 1448857:CCORG_RS01525
uniprot id: A0A7M1LGC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1448857:CCORG RS01210
gene id: 1448857:CCORG_RS01210
uniprot id: A0A7M1LGG0
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1448857:CCORG RS04820
gene id: 1448857:CCORG_RS04820
uniprot id: A0A7M1LEM9
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

1448857:CCORG RS03910
gene id: 1448857:CCORG_RS03910
uniprot id: A0A7M1LI78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane

1448857:CCORG RS04660
gene id: 1448857:CCORG_RS04660
uniprot id: A0A7M1LER2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1448857:CCORG RS03790
gene id: 1448857:CCORG_RS03790
uniprot id: A0A7M1LF60
names: Similarity
messages: Belongs to the GSP E family.

1448857:CCORG RS02865
gene id: 1448857:CCORG_RS02865
uniprot id: A0A7M1LGB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

1448857:CCORG RS05835
gene id: 1448857:CCORG_RS05835
uniprot id: A0A7M1LE40
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1448857:CCORG RS00530
gene id: 1448857:CCORG_RS00530
uniprot id: A0A7M1LHI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1448857:CCORG RS03025
gene id: 1448857:CCORG_RS03025
uniprot id: A0A7M1LIL6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1448857:CCORG RS01195
gene id: 1448857:CCORG_RS01195
uniprot id: A0A7M1LGF8
names: Function
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.

1448857:CCORG RS06250
gene id: 1448857:CCORG_RS06250
uniprot id: A0A7M1LFC4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gmhB family.
messages: Cytoplasm
messages: Monomer.

1448857:CCORG RS01700
gene id: 1448857:CCORG_RS01700
uniprot id: A0A7M1LHX6
names: Similarity
messages: Belongs to the bacterial secretin family.

1448857:CCORG RS02475
gene id: 1448857:CCORG_RS02475
uniprot id: A0A7M1LFW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1448857:CCORG RS00695
gene id: 1448857:CCORG_RS00695
uniprot id: A0A7M1LGP5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1448857:CCORG RS03210
gene id: 1448857:CCORG_RS03210
uniprot id: A0A7M1LHI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1448857:CCORG RS01605
gene id: 1448857:CCORG_RS01605
uniprot id: A0A7M1LGZ8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1448857:CCORG RS04765
gene id: 1448857:CCORG_RS04765
uniprot id: A0A7M1LEQ9
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS01895
gene id: 1448857:CCORG_RS01895
uniprot id: A0A7M1LG38
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1448857:CCORG RS05940
gene id: 1448857:CCORG_RS05940
uniprot id: A0A7M1LE17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Hydrolyzes 6-aminopenicillinic acid and 7-aminocephalosporanic acid (ACA) derivatives.
messages: Secreted

1448857:CCORG RS02455
gene id: 1448857:CCORG_RS02455
uniprot id: A0A7M1LIH5
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1448857:CCORG RS02085
gene id: 1448857:CCORG_RS02085
uniprot id: A0A7M1LFZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1448857:CCORG RS01355
gene id: 1448857:CCORG_RS01355
uniprot id: A0A7M1LH48
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS02680
gene id: 1448857:CCORG_RS02680
uniprot id: A0A7M1LG51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cytoplasm

1448857:CCORG RS01240
gene id: 1448857:CCORG_RS01240
uniprot id: A0A7M1LH52
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS01915
gene id: 1448857:CCORG_RS01915
uniprot id: A0A7M1LG54
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1448857:CCORG RS05860
gene id: 1448857:CCORG_RS05860
uniprot id: A0A7M1LFI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1448857:CCORG RS08470
gene id: 1448857:CCORG_RS08470
uniprot id: A0A7M1LHW0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS07590
gene id: 1448857:CCORG_RS07590
uniprot id: A0A7M1LKL7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1448857:CCORG RS08100
gene id: 1448857:CCORG_RS08100
uniprot id: A0A7M1LJJ1
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS02650
gene id: 1448857:CCORG_RS02650
uniprot id: A0A7M1LHS3
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1448857:CCORG RS04810
gene id: 1448857:CCORG_RS04810
uniprot id: A0A7M1LEN1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1448857:CCORG RS02045
gene id: 1448857:CCORG_RS02045
uniprot id: A0A7M1LG15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1448857:CCORG RS04625
gene id: 1448857:CCORG_RS04625
uniprot id: A0A7M1LG93
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1448857:CCORG RS08260
gene id: 1448857:CCORG_RS08260
uniprot id: A0A7M1LHB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1448857:CCORG RS08485
gene id: 1448857:CCORG_RS08485
uniprot id: A0A7M1LH75
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS02320
gene id: 1448857:CCORG_RS02320
uniprot id: A0A7M1LFX2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1448857:CCORG RS05465
gene id: 1448857:CCORG_RS05465
uniprot id: A0A7M1LEA7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

1448857:CCORG RS05705
gene id: 1448857:CCORG_RS05705
uniprot id: A0A7M1LE52
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1448857:CCORG RS01975
gene id: 1448857:CCORG_RS01975
uniprot id: A0A7M1LGH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1448857:CCORG RS02515
gene id: 1448857:CCORG_RS02515
uniprot id: A0A7M1LGJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1448857:CCORG RS04905
gene id: 1448857:CCORG_RS04905
uniprot id: A0A7M1LEZ4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1448857:CCORG RS05260
gene id: 1448857:CCORG_RS05260
uniprot id: A0A7M1LF35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

1448857:CCORG RS06455
gene id: 1448857:CCORG_RS06455
uniprot id: A0A7M1LDT0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1448857:CCORG RS00105
gene id: 1448857:CCORG_RS00105
uniprot id: A0A7M1LIV3
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1448857:CCORG RS06985
gene id: 1448857:CCORG_RS06985
uniprot id: A0A7M1LEZ3
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1448857:CCORG RS07125
gene id: 1448857:CCORG_RS07125
uniprot id: A0A7M1LDS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1448857:CCORG RS05025
gene id: 1448857:CCORG_RS05025
uniprot id: A0A7M1LGI9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS05295
gene id: 1448857:CCORG_RS05295
uniprot id: A0A7M1LGD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1448857:CCORG RS07025
gene id: 1448857:CCORG_RS07025
uniprot id: A0A7M1LIB4
names: Similarity
messages: Belongs to the fabD family.

1448857:CCORG RS00925
gene id: 1448857:CCORG_RS00925
uniprot id: A0A7M1LHC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1448857:CCORG RS08560
gene id: 1448857:CCORG_RS08560
uniprot id: A0A7M1LIY7
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS07205
gene id: 1448857:CCORG_RS07205
uniprot id: A0A7M1LEV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1448857:CCORG RS06270
gene id: 1448857:CCORG_RS06270
uniprot id: A0A7M1LEJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1448857:CCORG RS01815
gene id: 1448857:CCORG_RS01815
uniprot id: A0A7M1LI65
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1448857:CCORG RS02655
gene id: 1448857:CCORG_RS02655
uniprot id: A0A7M1LIT4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1448857:CCORG RS06055
gene id: 1448857:CCORG_RS06055
uniprot id: A0A7M1LDZ9
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1448857:CCORG RS05695
gene id: 1448857:CCORG_RS05695
uniprot id: A0A7M1LFL2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1448857:CCORG RS07065
gene id: 1448857:CCORG_RS07065
uniprot id: A0A7M1LDI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1448857:CCORG RS00100
gene id: 1448857:CCORG_RS00100
uniprot id: A0A7M1LK15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1448857:CCORG RS04805
gene id: 1448857:CCORG_RS04805
uniprot id: A0A7M1LF17
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

1448857:CCORG RS02885
gene id: 1448857:CCORG_RS02885
uniprot id: A0A7M1LFJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1448857:CCORG RS03450
gene id: 1448857:CCORG_RS03450
uniprot id: A0A7M1LFC7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1448857:CCORG RS07035
gene id: 1448857:CCORG_RS07035
uniprot id: A0A7M1LFF5
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

1448857:CCORG RS01395
gene id: 1448857:CCORG_RS01395
uniprot id: A0A7M1LH21
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1448857:CCORG RS00690
gene id: 1448857:CCORG_RS00690
uniprot id: A0A7M1LHF2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1448857:CCORG RS01555
gene id: 1448857:CCORG_RS01555
uniprot id: A0A7M1LH08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1448857:CCORG RS01300
gene id: 1448857:CCORG_RS01300
uniprot id: A0A7M1LGD7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1448857:CCORG RS08430
gene id: 1448857:CCORG_RS08430
uniprot id: A0A7M1LH50
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1448857:CCORG RS02370
gene id: 1448857:CCORG_RS02370
uniprot id: A0A7M1LFY3
names: Similarity
messages: Belongs to the RutC family.

1448857:CCORG RS05680
gene id: 1448857:CCORG_RS05680
uniprot id: A0A7M1LE63
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1448857:CCORG RS04745
gene id: 1448857:CCORG_RS04745
uniprot id: A0A7M1LFD3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS05885
gene id: 1448857:CCORG_RS05885
uniprot id: A0A7M1LE27
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1448857:CCORG RS03960
gene id: 1448857:CCORG_RS03960
uniprot id: A0A7M1LI70
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS07195
gene id: 1448857:CCORG_RS07195
uniprot id: A0A7M1LFD0
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1448857:CCORG RS05040
gene id: 1448857:CCORG_RS05040
uniprot id: A0A7M1LHL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Membrane

1448857:CCORG RS05275
gene id: 1448857:CCORG_RS05275
uniprot id: A0A7M1LER5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapB family.
messages: Binds 2 heme C groups per subunit.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Electron transfer subunit of the periplasmic nitrate reductase complex NapAB.
messages: Periplasm

1448857:CCORG RS05850
gene id: 1448857:CCORG_RS05850
uniprot id: A0A7M1LG12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1448857:CCORG RS02350
gene id: 1448857:CCORG_RS02350
uniprot id: A0A7M1LFU4
names: Subcellular Location Annotation
messages: Cytoplasm

1448857:CCORG RS04495
gene id: 1448857:CCORG_RS04495
uniprot id: A0A7M1LEU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1448857:CCORG RS01805
gene id: 1448857:CCORG_RS01805
uniprot id: A0A7M1LG52
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1448857:CCORG RS03935
gene id: 1448857:CCORG_RS03935
uniprot id: A0A7M1LFK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1448857:CCORG RS04080
gene id: 1448857:CCORG_RS04080
uniprot id: A0A7M1LH60
names: Similarity
messages: Belongs to the PhoH family.

1448857:CCORG RS08255
gene id: 1448857:CCORG_RS08255
uniprot id: A0A7M1LH83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1448857:CCORG RS01260
gene id: 1448857:CCORG_RS01260
uniprot id: A0A7M1LGF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1448857:CCORG RS06570
gene id: 1448857:CCORG_RS06570
uniprot id: A0A7M1LEF0
names: Similarity
messages: Belongs to the GPI family.

1448857:CCORG RS08205
gene id: 1448857:CCORG_RS08205
uniprot id: A0A7M1LH93
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1448857:CCORG RS03095
gene id: 1448857:CCORG_RS03095
uniprot id: A0A7M1LIK4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1448857:CCORG RS06165
gene id: 1448857:CCORG_RS06165
uniprot id: A0A7M1LDY0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1448857:CCORG RS03900
gene id: 1448857:CCORG_RS03900
uniprot id: A0A7M1LF45
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1448857:CCORG RS02765
gene id: 1448857:CCORG_RS02765
uniprot id: A0A7M1LGD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1448857:CCORG RS00355
gene id: 1448857:CCORG_RS00355
uniprot id: A0A7M1LHB5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1448857:CCORG RS00955
gene id: 1448857:CCORG_RS00955
uniprot id: A0A7M1LIP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1448857:CCORG RS08395
gene id: 1448857:CCORG_RS08395
uniprot id: A0A7M1LJ19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1448857:CCORG RS08190
gene id: 1448857:CCORG_RS08190
uniprot id: A0A7M1LHA1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1448857:CCORG RS02400
gene id: 1448857:CCORG_RS02400
uniprot id: A0A7M1LFT4
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS05480
gene id: 1448857:CCORG_RS05480
uniprot id: A0A7M1LFQ3
names: Similarity
messages: Belongs to the LOG family.

1448857:CCORG RS06300
gene id: 1448857:CCORG_RS06300
uniprot id: A0A7M1LFS9
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1448857:CCORG RS07560
gene id: 1448857:CCORG_RS07560
uniprot id: A0A7M1LID7
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS01015
gene id: 1448857:CCORG_RS01015
uniprot id: A0A7M1LJL1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1448857:CCORG RS02325
gene id: 1448857:CCORG_RS02325
uniprot id: A0A7M1LHX9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1448857:CCORG RS08080
gene id: 1448857:CCORG_RS08080
uniprot id: A0A7M1LHS6
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

1448857:CCORG RS07075
gene id: 1448857:CCORG_RS07075
uniprot id: A0A7M1LDT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1448857:CCORG RS06145
gene id: 1448857:CCORG_RS06145
uniprot id: A0A7M1LEM5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1448857:CCORG RS07225
gene id: 1448857:CCORG_RS07225
uniprot id: A0A7M1LDQ7
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1448857:CCORG RS03710
gene id: 1448857:CCORG_RS03710
uniprot id: A0A7M1LG00
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1448857:CCORG RS02025
gene id: 1448857:CCORG_RS02025
uniprot id: A0A7M1LGS8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1448857:CCORG RS05055
gene id: 1448857:CCORG_RS05055
uniprot id: A0A7M1LEH7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1448857:CCORG RS02175
gene id: 1448857:CCORG_RS02175
uniprot id: A0A7M1LJ21
names: Similarity
messages: Belongs to the peptidase S49 family.

1448857:CCORG RS00745
gene id: 1448857:CCORG_RS00745
uniprot id: A0A7M1LGN5
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1448857:CCORG RS06340
gene id: 1448857:CCORG_RS06340
uniprot id: A0A7M1LDV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1448857:CCORG RS02905
gene id: 1448857:CCORG_RS02905
uniprot id: A0A7M1LIN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS04105
gene id: 1448857:CCORG_RS04105
uniprot id: A0A7M1LFT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1448857:CCORG RS04465
gene id: 1448857:CCORG_RS04465
uniprot id: A0A7M1LHX1
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1448857:CCORG RS08210
gene id: 1448857:CCORG_RS08210
uniprot id: A0A7M1LHC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1448857:CCORG RS01935
gene id: 1448857:CCORG_RS01935
uniprot id: A0A7M1LHM1
names: Similarity
messages: Belongs to the UPF0763 family.

1448857:CCORG RS04305
gene id: 1448857:CCORG_RS04305
uniprot id: A0A7M1LH11
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1448857:CCORG RS01035
gene id: 1448857:CCORG_RS01035
uniprot id: A0A7M1LGI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1448857:CCORG RS04940
gene id: 1448857:CCORG_RS04940
uniprot id: A0A7M1LFA0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1448857:CCORG RS07580
gene id: 1448857:CCORG_RS07580
uniprot id: A0A7M1LHL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1448857:CCORG RS08135
gene id: 1448857:CCORG_RS08135
uniprot id: A0A7M1LHA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1448857:CCORG RS02845
gene id: 1448857:CCORG_RS02845
uniprot id: A0A7M1LFN3
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1448857:CCORG RS05205
gene id: 1448857:CCORG_RS05205
uniprot id: A0A7M1LFV8
names: Similarity
messages: Belongs to the TlyA family.

1448857:CCORG RS01280
gene id: 1448857:CCORG_RS01280
uniprot id: A0A7M1LIH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1448857:CCORG RS02615
gene id: 1448857:CCORG_RS02615
uniprot id: A0A7M1LGG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1448857:CCORG RS08130
gene id: 1448857:CCORG_RS08130
uniprot id: A0A7M1LHR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1448857:CCORG RS00800
gene id: 1448857:CCORG_RS00800
uniprot id: A0A7M1LGM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1448857:CCORG RS05235
gene id: 1448857:CCORG_RS05235
uniprot id: A0A7M1LEG8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1448857:CCORG RS04440
gene id: 1448857:CCORG_RS04440
uniprot id: A0A7M1LF92
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

1448857:CCORG RS00455
gene id: 1448857:CCORG_RS00455
uniprot id: A0A7M1LGT4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS05875
gene id: 1448857:CCORG_RS05875
uniprot id: A0A7M1LER6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1448857:CCORG RS01940
gene id: 1448857:CCORG_RS01940
uniprot id: A0A7M1LGS7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1448857:CCORG RS05845
gene id: 1448857:CCORG_RS05845
uniprot id: A0A7M1LE34
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.

1448857:CCORG RS02000
gene id: 1448857:CCORG_RS02000
uniprot id: A0A7M1LI35
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1448857:CCORG RS05240
gene id: 1448857:CCORG_RS05240
uniprot id: A0A7M1LEE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1448857:CCORG RS07445
gene id: 1448857:CCORG_RS07445
uniprot id: A0A7M1LER3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

1448857:CCORG RS08500
gene id: 1448857:CCORG_RS08500
uniprot id: A0A7M1LK54
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS08450
gene id: 1448857:CCORG_RS08450
uniprot id: A0A7M1LK66
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS01345
gene id: 1448857:CCORG_RS01345
uniprot id: A0A7M1LH33
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1448857:CCORG RS01340
gene id: 1448857:CCORG_RS01340
uniprot id: A0A7M1LI52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1448857:CCORG RS07100
gene id: 1448857:CCORG_RS07100
uniprot id: A0A7M1LGJ9
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1448857:CCORG RS01670
gene id: 1448857:CCORG_RS01670
uniprot id: A0A7M1LG66
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1448857:CCORG RS01595
gene id: 1448857:CCORG_RS01595
uniprot id: A0A7M1LGY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1448857:CCORG RS00685
gene id: 1448857:CCORG_RS00685
uniprot id: A0A7M1LIJ2
names: Similarity
messages: Belongs to the thioredoxin family.

1448857:CCORG RS02520
gene id: 1448857:CCORG_RS02520
uniprot id: A0A7M1LG79
names: Similarity
messages: Belongs to the universal stress protein A family.

1448857:CCORG RS02505
gene id: 1448857:CCORG_RS02505
uniprot id: A0A7M1LFR5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS02075
gene id: 1448857:CCORG_RS02075
uniprot id: A0A7M1LGQ5
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1448857:CCORG RS08055
gene id: 1448857:CCORG_RS08055
uniprot id: A0A7M1LJ94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1448857:CCORG RS07755
gene id: 1448857:CCORG_RS07755
uniprot id: A0A7M1LJQ9
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1448857:CCORG RS07355
gene id: 1448857:CCORG_RS07355
uniprot id: A0A7M1LDD8
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1448857:CCORG RS00010
gene id: 1448857:CCORG_RS00010
uniprot id: A0A7M1LHT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1448857:CCORG RS00545
gene id: 1448857:CCORG_RS00545
uniprot id: A0A7M1LH84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1448857:CCORG RS00920
gene id: 1448857:CCORG_RS00920
uniprot id: A0A7M1LGK9
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1448857:CCORG RS03805
gene id: 1448857:CCORG_RS03805
uniprot id: A0A7M1LI95
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS00645
gene id: 1448857:CCORG_RS00645
uniprot id: A0A7M1LHH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1448857:CCORG RS03890
gene id: 1448857:CCORG_RS03890
uniprot id: A0A7M1LF58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1448857:CCORG RS01175
gene id: 1448857:CCORG_RS01175
uniprot id: A0A7M1LJI4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1448857:CCORG RS08235
gene id: 1448857:CCORG_RS08235
uniprot id: A0A7M1LHW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1448857:CCORG RS05290
gene id: 1448857:CCORG_RS05290
uniprot id: A0A7M1LED6
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1448857:CCORG RS00160
gene id: 1448857:CCORG_RS00160
uniprot id: A0A7M1LHN7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably functions as a manganese efflux pump.

1448857:CCORG RS08400
gene id: 1448857:CCORG_RS08400
uniprot id: A0A7M1LHS4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS03090
gene id: 1448857:CCORG_RS03090
uniprot id: A0A7M1LHK7
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1448857:CCORG RS05805
gene id: 1448857:CCORG_RS05805
uniprot id: A0A7M1LH68
names: Similarity
messages: Belongs to the AdoMet synthase family.

1448857:CCORG RS06000
gene id: 1448857:CCORG_RS06000
uniprot id: A0A7M1LE08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1448857:CCORG RS00180
gene id: 1448857:CCORG_RS00180
uniprot id: A0A7M1LHE3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1448857:CCORG RS02850
gene id: 1448857:CCORG_RS02850
uniprot id: A0A7M1LHP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1448857:CCORG RS00220
gene id: 1448857:CCORG_RS00220
uniprot id: A0A7M1LIS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1448857:CCORG RS03915
gene id: 1448857:CCORG_RS03915
uniprot id: A0A7M1LGN8
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS08290
gene id: 1448857:CCORG_RS08290
uniprot id: A0A7M1LH80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1448857:CCORG RS06110
gene id: 1448857:CCORG_RS06110
uniprot id: A0A7M1LE16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1448857:CCORG RS02255
gene id: 1448857:CCORG_RS02255
uniprot id: A0A7M1LGC9
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS04295
gene id: 1448857:CCORG_RS04295
uniprot id: A0A7M1LEZ7
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1448857:CCORG RS03185
gene id: 1448857:CCORG_RS03185
uniprot id: A0A7M1LFG1
names: Similarity
messages: Belongs to the TrpC family.

1448857:CCORG RS07160
gene id: 1448857:CCORG_RS07160
uniprot id: A0A7M1LE58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1448857:CCORG RS01145
gene id: 1448857:CCORG_RS01145
uniprot id: A0A7M1LGX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell inner membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1448857:CCORG RS02815
gene id: 1448857:CCORG_RS02815
uniprot id: A0A7M1LGC4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS01045
gene id: 1448857:CCORG_RS01045
uniprot id: A0A7M1LGZ1
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1448857:CCORG RS05640
gene id: 1448857:CCORG_RS05640
uniprot id: A0A7M1LH99
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1448857:CCORG RS01665
gene id: 1448857:CCORG_RS01665
uniprot id: A0A7M1LGL9
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1448857:CCORG RS03235
gene id: 1448857:CCORG_RS03235
uniprot id: A0A7M1LI34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1448857:CCORG RS06555
gene id: 1448857:CCORG_RS06555
uniprot id: A0A7M1LF71
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1448857:CCORG RS04480
gene id: 1448857:CCORG_RS04480
uniprot id: A0A7M1LET8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1448857:CCORG RS08390
gene id: 1448857:CCORG_RS08390
uniprot id: A0A7M1LK74
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1448857:CCORG RS02015
gene id: 1448857:CCORG_RS02015
uniprot id: A0A7M1LGR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1448857:CCORG RS01230
gene id: 1448857:CCORG_RS01230
uniprot id: A0A7M1LJH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1448857:CCORG RS05110
gene id: 1448857:CCORG_RS05110
uniprot id: A0A7M1LF51
names: Similarity
messages: Belongs to the threonine synthase family.

1448857:CCORG RS01255
gene id: 1448857:CCORG_RS01255
uniprot id: A0A7M1LGV2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1448857:CCORG RS00435
gene id: 1448857:CCORG_RS00435
uniprot id: A0A7M1LJ00
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1448857:CCORG RS08590
gene id: 1448857:CCORG_RS08590
uniprot id: A0A7M1LH56
names: Similarity
messages: Belongs to the peptidase S51 family.

1448857:CCORG RS01415
gene id: 1448857:CCORG_RS01415
uniprot id: A0A7M1LGC0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.

1448857:CCORG RS04315
gene id: 1448857:CCORG_RS04315
uniprot id: A0A7M1LGG6
names: Similarity
messages: Belongs to the HsdR family.

1448857:CCORG RS02315
gene id: 1448857:CCORG_RS02315
uniprot id: A0A7M1LFY9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1448857:CCORG RS02990
gene id: 1448857:CCORG_RS02990
uniprot id: A0A7M1LGB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1448857:CCORG RS02620
gene id: 1448857:CCORG_RS02620
uniprot id: A0A7M1LFP0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS05710
gene id: 1448857:CCORG_RS05710
uniprot id: A0A7M1LEU5
names: Similarity
messages: Belongs to the CapA family.

1448857:CCORG RS07630
gene id: 1448857:CCORG_RS07630
uniprot id: A0A7M1LHM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1448857:CCORG RS08600
gene id: 1448857:CCORG_RS08600
uniprot id: A0A7M1LJ90
names: Similarity
messages: Belongs to the asparaginase 1 family.

1448857:CCORG RS04455
gene id: 1448857:CCORG_RS04455
uniprot id: A0A7M1LEV2
names: Similarity
messages: Belongs to the peptidase A31 family.

1448857:CCORG RS02310
gene id: 1448857:CCORG_RS02310
uniprot id: A0A7M1LFV4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1448857:CCORG RS05210
gene id: 1448857:CCORG_RS05210
uniprot id: A0A7M1LF47
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS03745
gene id: 1448857:CCORG_RS03745
uniprot id: A0A7M1LGS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1448857:CCORG RS00490
gene id: 1448857:CCORG_RS00490
uniprot id: A0A7M1LIY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1448857:CCORG RS06265
gene id: 1448857:CCORG_RS06265
uniprot id: A0A7M1LDV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1448857:CCORG RS02785
gene id: 1448857:CCORG_RS02785
uniprot id: A0A7M1LFL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1448857:CCORG RS00215
gene id: 1448857:CCORG_RS00215
uniprot id: A0A7M1LJZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1448857:CCORG RS05530
gene id: 1448857:CCORG_RS05530
uniprot id: A0A7M1LG84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1448857:CCORG RS02930
gene id: 1448857:CCORG_RS02930
uniprot id: A0A7M1LGC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1448857:CCORG RS01980
gene id: 1448857:CCORG_RS01980
uniprot id: A0A7M1LG16
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1448857:CCORG RS01870
gene id: 1448857:CCORG_RS01870
uniprot id: A0A7M1LG42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1448857:CCORG RS02360
gene id: 1448857:CCORG_RS02360
uniprot id: A0A7M1LGB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1448857:CCORG RS05865
gene id: 1448857:CCORG_RS05865
uniprot id: A0A7M1LES8
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1448857:CCORG RS01305
gene id: 1448857:CCORG_RS01305
uniprot id: A0A7M1LH57
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1448857:CCORG RS02635
gene id: 1448857:CCORG_RS02635
uniprot id: A0A7M1LFP5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1448857:CCORG RS01150
gene id: 1448857:CCORG_RS01150
uniprot id: A0A7M1LGG7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1448857:CCORG RS00580
gene id: 1448857:CCORG_RS00580
uniprot id: A0A7M1LIL4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1448857:CCORG RS00995
gene id: 1448857:CCORG_RS00995
uniprot id: A0A7M1LGJ1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1448857:CCORG RS05070
gene id: 1448857:CCORG_RS05070
uniprot id: A0A7M1LEI2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS02805
gene id: 1448857:CCORG_RS02805
uniprot id: A0A7M1LIQ5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1448857:CCORG RS06955
gene id: 1448857:CCORG_RS06955
uniprot id: A0A7M1LDV7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1448857:CCORG RS08355
gene id: 1448857:CCORG_RS08355
uniprot id: A0A7M1LHM5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1448857:CCORG RS07800
gene id: 1448857:CCORG_RS07800
uniprot id: A0A7M1LHH7
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1448857:CCORG RS08580
gene id: 1448857:CCORG_RS08580
uniprot id: A0A7M1LHI4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

1448857:CCORG RS03740
gene id: 1448857:CCORG_RS03740
uniprot id: A0A7M1LIA5
names: Similarity
messages: Belongs to the ClpX chaperone family. HslU subfamily.

1448857:CCORG RS01410
gene id: 1448857:CCORG_RS01410
uniprot id: A0A7M1LGR8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1448857:CCORG RS04585
gene id: 1448857:CCORG_RS04585
uniprot id: A0A7M1LFG7
names: Caution
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterohexamer of 3 UreA (alpha) and 3 UreB (beta) subunits.
messages: The orthologous protein is known as the alpha subunit (UreC) in most other bacteria.

1448857:CCORG RS00750
gene id: 1448857:CCORG_RS00750
uniprot id: A0A7M1LHF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1448857:CCORG RS08095
gene id: 1448857:CCORG_RS08095
uniprot id: A0A7M1LHC5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1448857:CCORG RS01650
gene id: 1448857:CCORG_RS01650
uniprot id: A0A7M1LG75
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS04795
gene id: 1448857:CCORG_RS04795
uniprot id: A0A7M1LEN2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1448857:CCORG RS04675
gene id: 1448857:CCORG_RS04675
uniprot id: A0A7M1LG80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

1448857:CCORG RS07945
gene id: 1448857:CCORG_RS07945
uniprot id: A0A7M1LHD7
names: Similarity
messages: Belongs to the catalase family.

1448857:CCORG RS01330
gene id: 1448857:CCORG_RS01330
uniprot id: A0A7M1LIG4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS05045
gene id: 1448857:CCORG_RS05045
uniprot id: A0A7M1LFZ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1448857:CCORG RS06460
gene id: 1448857:CCORG_RS06460
uniprot id: A0A7M1LFP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1448857:CCORG RS08275
gene id: 1448857:CCORG_RS08275
uniprot id: A0A7M1LK95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1448857:CCORG RS07120
gene id: 1448857:CCORG_RS07120
uniprot id: A0A7M1LE57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1448857:CCORG RS08515
gene id: 1448857:CCORG_RS08515
uniprot id: A0A7M1LH35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1448857:CCORG RS05895
gene id: 1448857:CCORG_RS05895
uniprot id: A0A7M1LE23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1448857:CCORG RS04125
gene id: 1448857:CCORG_RS04125
uniprot id: A0A7M1LF13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1448857:CCORG RS00090
gene id: 1448857:CCORG_RS00090
uniprot id: A0A7M1LH07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1448857:CCORG RS00110
gene id: 1448857:CCORG_RS00110
uniprot id: A0A7M1LHP4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1448857:CCORG RS01350
gene id: 1448857:CCORG_RS01350
uniprot id: A0A7M1LGD2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1448857:CCORG RS07055
gene id: 1448857:CCORG_RS07055
uniprot id: A0A7M1LHU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1448857:CCORG RS04535
gene id: 1448857:CCORG_RS04535
uniprot id: A0A7M1LFH6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1448857:CCORG RS01600
gene id: 1448857:CCORG_RS01600
uniprot id: A0A7M1LG85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1448857:CCORG RS06305
gene id: 1448857:CCORG_RS06305
uniprot id: A0A7M1LGY2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1448857:CCORG RS06900
gene id: 1448857:CCORG_RS06900
uniprot id: A0A7M1LDJ9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1448857:CCORG RS02900
gene id: 1448857:CCORG_RS02900
uniprot id: A0A7M1LHN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1448857:CCORG RS00630
gene id: 1448857:CCORG_RS00630
uniprot id: A0A7M1LIK2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS04420
gene id: 1448857:CCORG_RS04420
uniprot id: A0A7M1LGE1
names: Similarity
messages: Belongs to the HypE family.

1448857:CCORG RS07805
gene id: 1448857:CCORG_RS07805
uniprot id: A0A7M1LJP9
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1448857:CCORG RS07140
gene id: 1448857:CCORG_RS07140
uniprot id: A0A7M1LDH7
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1448857:CCORG RS07070
gene id: 1448857:CCORG_RS07070
uniprot id: A0A7M1LE66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1448857:CCORG RS06925
gene id: 1448857:CCORG_RS06925
uniprot id: A0A7M1LFH0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS01025
gene id: 1448857:CCORG_RS01025
uniprot id: A0A7M1LH89
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1448857:CCORG RS02625
gene id: 1448857:CCORG_RS02625
uniprot id: A0A7M1LGI0
names: Similarity
messages: Belongs to the glutamine synthetase family.

1448857:CCORG RS06465
gene id: 1448857:CCORG_RS06465
uniprot id: A0A7M1LGV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1448857:CCORG RS04470
gene id: 1448857:CCORG_RS04470
uniprot id: A0A7M1LGC8
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

1448857:CCORG RS02100
gene id: 1448857:CCORG_RS02100
uniprot id: A0A7M1LFZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1448857:CCORG RS04035
gene id: 1448857:CCORG_RS04035
uniprot id: A0A7M1LFU3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1448857:CCORG RS03220
gene id: 1448857:CCORG_RS03220
uniprot id: A0A7M1LH05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1448857:CCORG RS02215
gene id: 1448857:CCORG_RS02215
uniprot id: A0A7M1LG06
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1448857:CCORG RS03670
gene id: 1448857:CCORG_RS03670
uniprot id: A0A7M1LFA5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1448857:CCORG RS03215
gene id: 1448857:CCORG_RS03215
uniprot id: A0A7M1LII8
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: The fumarate reductase enzyme complex is required for fumarate respiration. This subunit anchors the complex in the membrane and binds a diheme cytochrome b.

1448857:CCORG RS05335
gene id: 1448857:CCORG_RS05335
uniprot id: A0A7M1LEE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1448857:CCORG RS02115
gene id: 1448857:CCORG_RS02115
uniprot id: A0A7M1LI18
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

1448857:CCORG RS00965
gene id: 1448857:CCORG_RS00965
uniprot id: A0A7M1LID5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1448857:CCORG RS07400
gene id: 1448857:CCORG_RS07400
uniprot id: A0A7M1LE18
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1448857:CCORG RS04560
gene id: 1448857:CCORG_RS04560
uniprot id: A0A7M1LGU7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1448857:CCORG RS01125
gene id: 1448857:CCORG_RS01125
uniprot id: A0A7M1LI98
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS02610
gene id: 1448857:CCORG_RS02610
uniprot id: A0A7M1LHA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1448857:CCORG RS05255
gene id: 1448857:CCORG_RS05255
uniprot id: A0A7M1LFU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1448857:CCORG RS07895
gene id: 1448857:CCORG_RS07895
uniprot id: A0A7M1LHE8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1448857:CCORG RS00880
gene id: 1448857:CCORG_RS00880
uniprot id: A0A7M1LGL3
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS07470
gene id: 1448857:CCORG_RS07470
uniprot id: A0A7M1LHN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1448857:CCORG RS04370
gene id: 1448857:CCORG_RS04370
uniprot id: A0A7M1LGF3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1448857:CCORG RS02495
gene id: 1448857:CCORG_RS02495
uniprot id: A0A7M1LHC0
names: Similarity
messages: Belongs to the GARS family.

1448857:CCORG RS04760
gene id: 1448857:CCORG_RS04760
uniprot id: A0A7M1LKY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

1448857:CCORG RS00915
gene id: 1448857:CCORG_RS00915
uniprot id: A0A7M1LHB0
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1448857:CCORG RS04750
gene id: 1448857:CCORG_RS04750
uniprot id: A0A7M1LF28
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS04095
gene id: 1448857:CCORG_RS04095
uniprot id: A0A7M1LFT3
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1448857:CCORG RS04770
gene id: 1448857:CCORG_RS04770
uniprot id: A0A7M1LEP1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS03015
gene id: 1448857:CCORG_RS03015
uniprot id: A0A7M1LJX3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1448857:CCORG RS00115
gene id: 1448857:CCORG_RS00115
uniprot id: A0A7M1LH00
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1448857:CCORG RS03160
gene id: 1448857:CCORG_RS03160
uniprot id: A0A7M1LH15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1448857:CCORG RS03110
gene id: 1448857:CCORG_RS03110
uniprot id: A0A7M1LFF4
names: Similarity
messages: Belongs to the UbiD family.

1448857:CCORG RS01420
gene id: 1448857:CCORG_RS01420
uniprot id: A0A7M1LGE4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1448857:CCORG RS02685
gene id: 1448857:CCORG_RS02685
uniprot id: A0A7M1LFN6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1448857:CCORG RS00700
gene id: 1448857:CCORG_RS00700
uniprot id: A0A7M1LHG6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS01430
gene id: 1448857:CCORG_RS01430
uniprot id: A0A7M1LID9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1448857:CCORG RS00275
gene id: 1448857:CCORG_RS00275
uniprot id: A0A7M1LHL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1448857:CCORG RS00590
gene id: 1448857:CCORG_RS00590
uniprot id: A0A7M1LGR6
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS02230
gene id: 1448857:CCORG_RS02230
uniprot id: A0A7M1LJ11
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS04425
gene id: 1448857:CCORG_RS04425
uniprot id: A0A7M1LFL7
names: Similarity
messages: Belongs to the HypD family.

1448857:CCORG RS03930
gene id: 1448857:CCORG_RS03930
uniprot id: A0A7M1LFV9
names: Similarity
messages: Belongs to the FeoA family.

1448857:CCORG RS05820
gene id: 1448857:CCORG_RS05820
uniprot id: A0A7M1LE31
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1448857:CCORG RS03380
gene id: 1448857:CCORG_RS03380
uniprot id: A0A7M1LFE7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1448857:CCORG RS01000
gene id: 1448857:CCORG_RS01000
uniprot id: A0A7M1LGN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1448857:CCORG RS07860
gene id: 1448857:CCORG_RS07860
uniprot id: A0A7M1LJN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1448857:CCORG RS03725
gene id: 1448857:CCORG_RS03725
uniprot id: A0A7M1LF95
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1448857:CCORG RS03925
gene id: 1448857:CCORG_RS03925
uniprot id: A0A7M1LF34
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1448857:CCORG RS04740
gene id: 1448857:CCORG_RS04740
uniprot id: A0A7M1LEP2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1448857:CCORG RS07275
gene id: 1448857:CCORG_RS07275
uniprot id: A0A7M1LDP4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

1448857:CCORG RS00315
gene id: 1448857:CCORG_RS00315
uniprot id: A0A7M1LGX1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1448857:CCORG RS07130
gene id: 1448857:CCORG_RS07130
uniprot id: A0A7M1LDG1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1448857:CCORG RS06255
gene id: 1448857:CCORG_RS06255
uniprot id: A0A7M1LHX2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS02910
gene id: 1448857:CCORG_RS02910
uniprot id: A0A7M1LH55
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1448857:CCORG RS07845
gene id: 1448857:CCORG_RS07845
uniprot id: A0A7M1LHF8
names: Similarity
messages: Belongs to the ModE family.

1448857:CCORG RS01400
gene id: 1448857:CCORG_RS01400
uniprot id: A0A7M1LGC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1448857:CCORG RS04870
gene id: 1448857:CCORG_RS04870
uniprot id: A0A7M1LEL8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1448857:CCORG RS08615
gene id: 1448857:CCORG_RS08615
uniprot id: A0A7M1LHR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1448857:CCORG RS04875
gene id: 1448857:CCORG_RS04875
uniprot id: A0A7M1LGN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1448857:CCORG RS05325
gene id: 1448857:CCORG_RS05325
uniprot id: A0A7M1LEQ7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1448857:CCORG RS08145
gene id: 1448857:CCORG_RS08145
uniprot id: A0A7M1LHB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1448857:CCORG RS07965
gene id: 1448857:CCORG_RS07965
uniprot id: A0A7M1LKE0
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS07135
gene id: 1448857:CCORG_RS07135
uniprot id: A0A7M1LDJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1448857:CCORG RS00080
gene id: 1448857:CCORG_RS00080
uniprot id: A0A7M1LH04
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1448857:CCORG RS08215
gene id: 1448857:CCORG_RS08215
uniprot id: A0A7M1LHA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1448857:CCORG RS05785
gene id: 1448857:CCORG_RS05785
uniprot id: A0A7M1LE50
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1448857:CCORG RS04395
gene id: 1448857:CCORG_RS04395
uniprot id: A0A7M1LEW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

1448857:CCORG RS00190
gene id: 1448857:CCORG_RS00190
uniprot id: A0A7M1LH17
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1448857:CCORG RS05595
gene id: 1448857:CCORG_RS05595
uniprot id: A0A7M1LFN2
names: Similarity
messages: Belongs to the YggT family.

1448857:CCORG RS08620
gene id: 1448857:CCORG_RS08620
uniprot id: A0A7M1LH16
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1448857:CCORG RS02580
gene id: 1448857:CCORG_RS02580
uniprot id: A0A7M1LG69
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1448857:CCORG RS06640
gene id: 1448857:CCORG_RS06640
uniprot id: A0A7M1LDQ3
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspF family.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS08125
gene id: 1448857:CCORG_RS08125
uniprot id: A0A7M1LI26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1448857:CCORG RS04960
gene id: 1448857:CCORG_RS04960
uniprot id: A0A7M1LEK2
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1448857:CCORG RS07820
gene id: 1448857:CCORG_RS07820
uniprot id: A0A7M1LI37
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1448857:CCORG RS00705
gene id: 1448857:CCORG_RS00705
uniprot id: A0A7M1LH47
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1448857:CCORG RS06675
gene id: 1448857:CCORG_RS06675
uniprot id: A0A7M1LE01
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1448857:CCORG RS00935
gene id: 1448857:CCORG_RS00935
uniprot id: A0A7M1LH10
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1448857:CCORG RS06795
gene id: 1448857:CCORG_RS06795
uniprot id: A0A7M1LDM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

1448857:CCORG RS05795
gene id: 1448857:CCORG_RS05795
uniprot id: A0A7M1LE46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1448857:CCORG RS01450
gene id: 1448857:CCORG_RS01450
uniprot id: A0A7M1LGB1
names: Similarity
messages: Belongs to the protease inhibitor I11 (ecotin) family.

1448857:CCORG RS06235
gene id: 1448857:CCORG_RS06235
uniprot id: A0A7M1LHV5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1448857:CCORG RS05650
gene id: 1448857:CCORG_RS05650
uniprot id: A0A7M1LEW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1448857:CCORG RS06975
gene id: 1448857:CCORG_RS06975
uniprot id: A0A7M1LFG5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS05245
gene id: 1448857:CCORG_RS05245
uniprot id: A0A7M1LGE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1448857:CCORG RS00240
gene id: 1448857:CCORG_RS00240
uniprot id: A0A7M1LHD2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1448857:CCORG RS02020
gene id: 1448857:CCORG_RS02020
uniprot id: A0A7M1LG09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1448857:CCORG RS05130
gene id: 1448857:CCORG_RS05130
uniprot id: A0A7M1LEJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1448857:CCORG RS04735
gene id: 1448857:CCORG_RS04735
uniprot id: A0A7M1LFE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1448857:CCORG RS04415
gene id: 1448857:CCORG_RS04415
uniprot id: A0A7M1LHY2
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1448857:CCORG RS08230
gene id: 1448857:CCORG_RS08230
uniprot id: A0A7M1LJ50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1448857:CCORG RS07670
gene id: 1448857:CCORG_RS07670
uniprot id: A0A7M1LHJ5
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1448857:CCORG RS07730
gene id: 1448857:CCORG_RS07730
uniprot id: A0A7M1LHY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

1448857:CCORG RS01060
gene id: 1448857:CCORG_RS01060
uniprot id: A0A7M1LGI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1448857:CCORG RS02705
gene id: 1448857:CCORG_RS02705
uniprot id: A0A7M1LIS5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1448857:CCORG RS08545
gene id: 1448857:CCORG_RS08545
uniprot id: A0A7M1LH39
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1448857:CCORG RS08335
gene id: 1448857:CCORG_RS08335
uniprot id: A0A7M1LJ30
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1448857:CCORG RS00265
gene id: 1448857:CCORG_RS00265
uniprot id: A0A7M1LJY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1448857:CCORG RS00600
gene id: 1448857:CCORG_RS00600
uniprot id: A0A7M1LH74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1448857:CCORG RS05085
gene id: 1448857:CCORG_RS05085
uniprot id: A0A7M1LGI1
names: Similarity
messages: Belongs to the NAD synthetase family.

1448857:CCORG RS08360
gene id: 1448857:CCORG_RS08360
uniprot id: A0A7M1LH63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Homodimer.

1448857:CCORG RS07810
gene id: 1448857:CCORG_RS07810
uniprot id: A0A7M1LKH0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS06980
gene id: 1448857:CCORG_RS06980
uniprot id: A0A7M1LGL8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1448857:CCORG RS05190
gene id: 1448857:CCORG_RS05190
uniprot id: A0A7M1LEF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

1448857:CCORG RS01165
gene id: 1448857:CCORG_RS01165
uniprot id: A0A7M1LGG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1448857:CCORG RS00430
gene id: 1448857:CCORG_RS00430
uniprot id: A0A7M1LGV0
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1448857:CCORG RS01950
gene id: 1448857:CCORG_RS01950
uniprot id: A0A7M1LGU3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1448857:CCORG RS00005
gene id: 1448857:CCORG_RS00005
uniprot id: A0A7M1LK07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1448857:CCORG RS04430
gene id: 1448857:CCORG_RS04430
uniprot id: A0A7M1LEU6
names: Similarity
messages: Belongs to the HupF/HypC family.

1448857:CCORG RS00865
gene id: 1448857:CCORG_RS00865
uniprot id: A0A7M1LGM0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1448857:CCORG RS07910
gene id: 1448857:CCORG_RS07910
uniprot id: A0A7M1LJM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1448857:CCORG RS04975
gene id: 1448857:CCORG_RS04975
uniprot id: A0A7M1LGK5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1448857:CCORG RS00195
gene id: 1448857:CCORG_RS00195
uniprot id: A0A7M1LGY8
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS05565
gene id: 1448857:CCORG_RS05565
uniprot id: A0A7M1LE88
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1448857:CCORG RS01365
gene id: 1448857:CCORG_RS01365
uniprot id: A0A7M1LGD1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1448857:CCORG RS03200
gene id: 1448857:CCORG_RS03200
uniprot id: A0A7M1LFK4
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1448857:CCORG RS03385
gene id: 1448857:CCORG_RS03385
uniprot id: A0A7M1LFC6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

1448857:CCORG RS01485
gene id: 1448857:CCORG_RS01485
uniprot id: A0A7M1LJD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

1448857:CCORG RS04900
gene id: 1448857:CCORG_RS04900
uniprot id: A0A7M1LF98
names: Subcellular Location Annotation
messages: Mitochondrion

1448857:CCORG RS02740
gene id: 1448857:CCORG_RS02740
uniprot id: A0A7M1LFR9
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

1448857:CCORG RS08120
gene id: 1448857:CCORG_RS08120
uniprot id: A0A7M1LHB1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1448857:CCORG RS07080
gene id: 1448857:CCORG_RS07080
uniprot id: A0A7M1LDH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1448857:CCORG RS01215
gene id: 1448857:CCORG_RS01215
uniprot id: A0A7M1LGI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1448857:CCORG RS01170
gene id: 1448857:CCORG_RS01170
uniprot id: A0A7M1LIJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1448857:CCORG RS02895
gene id: 1448857:CCORG_RS02895
uniprot id: A0A7M1LFM1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1448857:CCORG RS07785
gene id: 1448857:CCORG_RS07785
uniprot id: A0A7M1LHW6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1448857:CCORG RS00960
gene id: 1448857:CCORG_RS00960
uniprot id: A0A7M1LJM1
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS03905
gene id: 1448857:CCORG_RS03905
uniprot id: A0A7M1LH87
names: Similarity
messages: Belongs to the peptidase M16 family.

1448857:CCORG RS06655
gene id: 1448857:CCORG_RS06655
uniprot id: A0A7M1LF53
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

1448857:CCORG RS01890
gene id: 1448857:CCORG_RS01890
uniprot id: A0A7M1LGT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1448857:CCORG RS03180
gene id: 1448857:CCORG_RS03180
uniprot id: A0A7M1LFW5
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

1448857:CCORG RS05660
gene id: 1448857:CCORG_RS05660
uniprot id: A0A7M1LEV5
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1448857:CCORG RS07525
gene id: 1448857:CCORG_RS07525
uniprot id: A0A7M1LJV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1448857:CCORG RS06115
gene id: 1448857:CCORG_RS06115
uniprot id: A0A7M1LHV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1448857:CCORG RS04715
gene id: 1448857:CCORG_RS04715
uniprot id: A0A7M1LEQ3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS07390
gene id: 1448857:CCORG_RS07390
uniprot id: A0A7M1LES3
names: Similarity
messages: Belongs to the nitroreductase family.

1448857:CCORG RS06095
gene id: 1448857:CCORG_RS06095
uniprot id: A0A7M1LEM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1448857:CCORG RS01405
gene id: 1448857:CCORG_RS01405
uniprot id: A0A7M1LH38
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1448857:CCORG RS01830
gene id: 1448857:CCORG_RS01830
uniprot id: A0A7M1LGU6
names: Cofactor
names: Miscellaneous
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1448857:CCORG RS06545
gene id: 1448857:CCORG_RS06545
uniprot id: A0A7M1LFN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1448857:CCORG RS04565
gene id: 1448857:CCORG_RS04565
uniprot id: A0A7M1LHU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1448857:CCORG RS06895
gene id: 1448857:CCORG_RS06895
uniprot id: A0A7M1LDW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

1448857:CCORG RS05185
gene id: 1448857:CCORG_RS05185
uniprot id: A0A7M1LEH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1448857:CCORG RS01205
gene id: 1448857:CCORG_RS01205
uniprot id: A0A7M1LGW3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1448857:CCORG RS01360
gene id: 1448857:CCORG_RS01360
uniprot id: A0A7M1LGS9
names: Similarity
messages: Belongs to the GSP E family.

1448857:CCORG RS00050
gene id: 1448857:CCORG_RS00050
uniprot id: A0A7M1LK23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1448857:CCORG RS06290
gene id: 1448857:CCORG_RS06290
uniprot id: A0A7M1LDY5
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1448857:CCORG RS07240
gene id: 1448857:CCORG_RS07240
uniprot id: A0A7M1LDF6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1448857:CCORG RS07095
gene id: 1448857:CCORG_RS07095
uniprot id: A0A7M1LFF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase B chain family.
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Membrane

1448857:CCORG RS04845
gene id: 1448857:CCORG_RS04845
uniprot id: A0A7M1LEM1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1448857:CCORG RS03795
gene id: 1448857:CCORG_RS03795
uniprot id: A0A7M1LHA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1448857:CCORG RS05925
gene id: 1448857:CCORG_RS05925
uniprot id: A0A7M1LE12
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS02935
gene id: 1448857:CCORG_RS02935
uniprot id: A0A7M1LFZ9
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1448857:CCORG RS03230
gene id: 1448857:CCORG_RS03230
uniprot id: A0A7M1LFD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1448857:CCORG RS07780
gene id: 1448857:CCORG_RS07780
uniprot id: A0A7M1LI92
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1448857:CCORG RS03920
gene id: 1448857:CCORG_RS03920
uniprot id: A0A7M1LFW2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1448857:CCORG RS02245
gene id: 1448857:CCORG_RS02245
uniprot id: A0A7M1LFW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1448857:CCORG RS01995
gene id: 1448857:CCORG_RS01995
uniprot id: A0A7M1LG23
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1448857:CCORG RS05575
gene id: 1448857:CCORG_RS05575
uniprot id: A0A7M1LEA6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS06930
gene id: 1448857:CCORG_RS06930
uniprot id: A0A7M1LGM6
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1448857:CCORG RS06060
gene id: 1448857:CCORG_RS06060
uniprot id: A0A7M1LE26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1448857:CCORG RS05730
gene id: 1448857:CCORG_RS05730
uniprot id: A0A7M1LE78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1448857:CCORG RS03830
gene id: 1448857:CCORG_RS03830
uniprot id: A0A7M1LFL5
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1448857:CCORG RS02605
gene id: 1448857:CCORG_RS02605
uniprot id: A0A7M1LIU5
names: Similarity
messages: Belongs to the peptidase M16 family.

1448857:CCORG RS04100
gene id: 1448857:CCORG_RS04100
uniprot id: A0A7M1LF07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1448857:CCORG RS05755
gene id: 1448857:CCORG_RS05755
uniprot id: A0A7M1LFK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1448857:CCORG RS00235
gene id: 1448857:CCORG_RS00235
uniprot id: A0A7M1LHQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1448857:CCORG RS01865
gene id: 1448857:CCORG_RS01865
uniprot id: A0A7M1LG64
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1448857:CCORG RS02485
gene id: 1448857:CCORG_RS02485
uniprot id: A0A7M1LHU5
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1448857:CCORG RS07760
gene id: 1448857:CCORG_RS07760
uniprot id: A0A7M1LKI5
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1448857:CCORG RS06280
gene id: 1448857:CCORG_RS06280
uniprot id: A0A7M1LE76
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1448857:CCORG RS01845
gene id: 1448857:CCORG_RS01845
uniprot id: A0A7M1LGJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1448857:CCORG RS03085
gene id: 1448857:CCORG_RS03085
uniprot id: A0A7M1LFI4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1448857:CCORG RS02110
gene id: 1448857:CCORG_RS02110
uniprot id: A0A7M1LG08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

1448857:CCORG RS05810
gene id: 1448857:CCORG_RS05810
uniprot id: A0A7M1LFJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Membrane

1448857:CCORG RS05415
gene id: 1448857:CCORG_RS05415
uniprot id: A0A7M1LHE1
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS08380
gene id: 1448857:CCORG_RS08380
uniprot id: A0A7M1LH73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1448857:CCORG RS05600
gene id: 1448857:CCORG_RS05600
uniprot id: A0A7M1LEX9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1448857:CCORG RS00170
gene id: 1448857:CCORG_RS00170
uniprot id: A0A7M1LGY9
names: Similarity
messages: Belongs to the universal stress protein A family.

1448857:CCORG RS00950
gene id: 1448857:CCORG_RS00950
uniprot id: A0A7M1LGK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1448857:CCORG RS08270
gene id: 1448857:CCORG_RS08270
uniprot id: A0A7M1LJG0
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1448857:CCORG RS02040
gene id: 1448857:CCORG_RS02040
uniprot id: A0A7M1LG36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1448857:CCORG RS02330
gene id: 1448857:CCORG_RS02330
uniprot id: A0A7M1LIZ1
names: Similarity
messages: Belongs to the XseB family.

1448857:CCORG RS01885
gene id: 1448857:CCORG_RS01885
uniprot id: A0A7M1LHN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1448857:CCORG RS01645
gene id: 1448857:CCORG_RS01645
uniprot id: A0A7M1LGX5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1448857:CCORG RS08225
gene id: 1448857:CCORG_RS08225
uniprot id: A0A7M1LKA5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1448857:CCORG RS00200
gene id: 1448857:CCORG_RS00200
uniprot id: A0A7M1LJW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1448857:CCORG RS02565
gene id: 1448857:CCORG_RS02565
uniprot id: A0A7M1LGH2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1448857:CCORG RS01445
gene id: 1448857:CCORG_RS01445
uniprot id: A0A7M1LH13
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1448857:CCORG RS02775
gene id: 1448857:CCORG_RS02775
uniprot id: A0A7M1LGF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1448857:CCORG RS04310
gene id: 1448857:CCORG_RS04310
uniprot id: A0A7M1LI01
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1448857:CCORG RS06625
gene id: 1448857:CCORG_RS06625
uniprot id: A0A7M1LE11
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1448857:CCORG RS08425
gene id: 1448857:CCORG_RS08425
uniprot id: A0A7M1LHU1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1448857:CCORG RS04595
gene id: 1448857:CCORG_RS04595
uniprot id: A0A7M1LES2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1448857:CCORG RS02575
gene id: 1448857:CCORG_RS02575
uniprot id: A0A7M1LGI8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1448857:CCORG RS00655
gene id: 1448857:CCORG_RS00655
uniprot id: A0A7M1LGQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1448857:CCORG RS08575
gene id: 1448857:CCORG_RS08575
uniprot id: A0A7M1LHU4
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS04880
gene id: 1448857:CCORG_RS04880
uniprot id: A0A7M1LHP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1448857:CCORG RS02095
gene id: 1448857:CCORG_RS02095
uniprot id: A0A7M1LGF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1448857:CCORG RS06240
gene id: 1448857:CCORG_RS06240
uniprot id: A0A7M1LFT9
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

1448857:CCORG RS07900
gene id: 1448857:CCORG_RS07900
uniprot id: A0A7M1LHH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1448857:CCORG RS04290
gene id: 1448857:CCORG_RS04290
uniprot id: A0A7M1LEY5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1448857:CCORG RS00810
gene id: 1448857:CCORG_RS00810
uniprot id: A0A7M1LH28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Hydrolyzes 6-aminopenicillinic acid and 7-aminocephalosporanic acid (ACA) derivatives.
messages: Secreted

1448857:CCORG RS01200
gene id: 1448857:CCORG_RS01200
uniprot id: A0A7M1LH81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1448857:CCORG RS06940
gene id: 1448857:CCORG_RS06940
uniprot id: A0A7M1LE97
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

1448857:CCORG RS06195
gene id: 1448857:CCORG_RS06195
uniprot id: A0A7M1LEL6
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS06530
gene id: 1448857:CCORG_RS06530
uniprot id: A0A7M1LDS1
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

1448857:CCORG RS02695
gene id: 1448857:CCORG_RS02695
uniprot id: A0A7M1LFQ6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1448857:CCORG RS00875
gene id: 1448857:CCORG_RS00875
uniprot id: A0A7M1LH19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1448857:CCORG RS04285
gene id: 1448857:CCORG_RS04285
uniprot id: A0A7M1LFD1
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

1448857:CCORG RS04390
gene id: 1448857:CCORG_RS04390
uniprot id: A0A7M1LFA7
names: Similarity
messages: Belongs to the peptidase S51 family.

1448857:CCORG RS08585
gene id: 1448857:CCORG_RS08585
uniprot id: A0A7M1LH23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

1448857:CCORG RS02660
gene id: 1448857:CCORG_RS02660
uniprot id: A0A7M1LH96
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1448857:CCORG RS01780
gene id: 1448857:CCORG_RS01780
uniprot id: A0A7M1LG56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1448857:CCORG RS02010
gene id: 1448857:CCORG_RS02010
uniprot id: A0A7M1LHL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1448857:CCORG RS01005
gene id: 1448857:CCORG_RS01005
uniprot id: A0A7M1LGJ6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS05300
gene id: 1448857:CCORG_RS05300
uniprot id: A0A7M1LHG1
names: Similarity
messages: Belongs to the DprA/Smf family.

1448857:CCORG RS07330
gene id: 1448857:CCORG_RS07330
uniprot id: A0A7M1LDN4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1448857:CCORG RS03135
gene id: 1448857:CCORG_RS03135
uniprot id: A0A7M1LFH1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

1448857:CCORG RS05150
gene id: 1448857:CCORG_RS05150
uniprot id: A0A7M1LFW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1448857:CCORG RS04345
gene id: 1448857:CCORG_RS04345
uniprot id: A0A7M1LEX3
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS06435
gene id: 1448857:CCORG_RS06435
uniprot id: A0A7M1LE41
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1448857:CCORG RS07830
gene id: 1448857:CCORG_RS07830
uniprot id: A0A7M1LI80
names: Similarity
messages: Belongs to the citrate synthase family.

1448857:CCORG RS06585
gene id: 1448857:CCORG_RS06585
uniprot id: A0A7M1LDT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1448857:CCORG RS03695
gene id: 1448857:CCORG_RS03695
uniprot id: A0A7M1LGT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1448857:CCORG RS05515
gene id: 1448857:CCORG_RS05515
uniprot id: A0A7M1LEB7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1448857:CCORG RS07665
gene id: 1448857:CCORG_RS07665
uniprot id: A0A7M1LI71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1448857:CCORG RS07290
gene id: 1448857:CCORG_RS07290
uniprot id: A0A7M1LDF0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1448857:CCORG RS04570
gene id: 1448857:CCORG_RS04570
uniprot id: A0A7M1LGA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1448857:CCORG RS03880
gene id: 1448857:CCORG_RS03880
uniprot id: A0A7M1LIK6
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1448857:CCORG RS07690
gene id: 1448857:CCORG_RS07690
uniprot id: A0A7M1LHL8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1448857:CCORG RS07575
gene id: 1448857:CCORG_RS07575
uniprot id: A0A7M1LHN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1448857:CCORG RS05775
gene id: 1448857:CCORG_RS05775
uniprot id: A0A7M1LET5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1448857:CCORG RS00940
gene id: 1448857:CCORG_RS00940
uniprot id: A0A7M1LGK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1448857:CCORG RS07660
gene id: 1448857:CCORG_RS07660
uniprot id: A0A7M1LJH1
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS05105
gene id: 1448857:CCORG_RS05105
uniprot id: A0A7M1LEG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1448857:CCORG RS08480
gene id: 1448857:CCORG_RS08480
uniprot id: A0A7M1LH43
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS07040
gene id: 1448857:CCORG_RS07040
uniprot id: A0A7M1LGK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1448857:CCORG RS02440
gene id: 1448857:CCORG_RS02440
uniprot id: A0A7M1LHD1
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1448857:CCORG RS04910
gene id: 1448857:CCORG_RS04910
uniprot id: A0A7M1LEL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1448857:CCORG RS08490
gene id: 1448857:CCORG_RS08490
uniprot id: A0A7M1LH53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Hydrolyzes 6-aminopenicillinic acid and 7-aminocephalosporanic acid (ACA) derivatives.
messages: Secreted

1448857:CCORG RS04780
gene id: 1448857:CCORG_RS04780
uniprot id: A0A7M1LHR2
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

1448857:CCORG RS00760
gene id: 1448857:CCORG_RS00760
uniprot id: A0A7M1LGM8
names: Similarity
messages: Belongs to the CarB family.

1448857:CCORG RS02420
gene id: 1448857:CCORG_RS02420
uniprot id: A0A7M1LFX5
names: Similarity
messages: Belongs to the MQO family.

1448857:CCORG RS04240
gene id: 1448857:CCORG_RS04240
uniprot id: A0A7M1LF08
names: Similarity
messages: Belongs to the UPF0423 family.

1448857:CCORG RS06950
gene id: 1448857:CCORG_RS06950
uniprot id: A0A7M1LE85
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS01495
gene id: 1448857:CCORG_RS01495
uniprot id: A0A7M1LH03
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1448857:CCORG RS00150
gene id: 1448857:CCORG_RS00150
uniprot id: A0A7M1LK05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1448857:CCORG RS04590
gene id: 1448857:CCORG_RS04590
uniprot id: A0A7M1LF62
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1448857:CCORG RS03815
gene id: 1448857:CCORG_RS03815
uniprot id: A0A7M1LFY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 'phage' integrase family. XerH subfamily.
messages: Cytoplasm
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1448857:CCORG RS05555
gene id: 1448857:CCORG_RS05555
uniprot id: A0A7M1LEX1
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1448857:CCORG RS02840
gene id: 1448857:CCORG_RS02840
uniprot id: A0A7M1LFQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1448857:CCORG RS01295
gene id: 1448857:CCORG_RS01295
uniprot id: A0A7M1LH42
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.

1448857:CCORG RS07675
gene id: 1448857:CCORG_RS07675
uniprot id: A0A7M1LIB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1448857:CCORG RS04025
gene id: 1448857:CCORG_RS04025
uniprot id: A0A7M1LI56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1448857:CCORG RS07190
gene id: 1448857:CCORG_RS07190
uniprot id: A0A7M1LDG6
names: Similarity
messages: Belongs to the TrpF family.

1448857:CCORG RS02570
gene id: 1448857:CCORG_RS02570
uniprot id: A0A7M1LFQ1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1448857:CCORG RS05000
gene id: 1448857:CCORG_RS05000
uniprot id: A0A7M1LF76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1448857:CCORG RS01675
gene id: 1448857:CCORG_RS01675
uniprot id: A0A7M1LG97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1448857:CCORG RS02500
gene id: 1448857:CCORG_RS02500
uniprot id: A0A7M1LGI3
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS07485
gene id: 1448857:CCORG_RS07485
uniprot id: A0A7M1LJK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

1448857:CCORG RS02835
gene id: 1448857:CCORG_RS02835
uniprot id: A0A7M1LFK6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS04365
gene id: 1448857:CCORG_RS04365
uniprot id: A0A7M1LHZ1
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1448857:CCORG RS05630
gene id: 1448857:CCORG_RS05630
uniprot id: A0A7M1LE72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1448857:CCORG RS03345
gene id: 1448857:CCORG_RS03345
uniprot id: A0A7M1LG50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1448857:CCORG RS03735
gene id: 1448857:CCORG_RS03735
uniprot id: A0A7M1LHB4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1448857:CCORG RS01745
gene id: 1448857:CCORG_RS01745
uniprot id: A0A7M1LJ86
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

1448857:CCORG RS00420
gene id: 1448857:CCORG_RS00420
uniprot id: A0A7M1LGT9
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

1448857:CCORG RS05975
gene id: 1448857:CCORG_RS05975
uniprot id: A0A7M1LEQ4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1448857:CCORG RS02525
gene id: 1448857:CCORG_RS02525
uniprot id: A0A7M1LFR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1448857:CCORG RS08305
gene id: 1448857:CCORG_RS08305
uniprot id: A0A7M1LH72
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1448857:CCORG RS02640
gene id: 1448857:CCORG_RS02640
uniprot id: A0A7M1LFT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1448857:CCORG RS05075
gene id: 1448857:CCORG_RS05075
uniprot id: A0A7M1LEK1
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS06010
gene id: 1448857:CCORG_RS06010
uniprot id: A0A7M1LE35
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS04030
gene id: 1448857:CCORG_RS04030
uniprot id: A0A7M1LGL7
names: Function
names: Similarity
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Cell wall formation.

1448857:CCORG RS00980
gene id: 1448857:CCORG_RS00980
uniprot id: A0A7M1LGJ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1448857:CCORG RS01310
gene id: 1448857:CCORG_RS01310
uniprot id: A0A7M1LGT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1448857:CCORG RS07245
gene id: 1448857:CCORG_RS07245
uniprot id: A0A7M1LFC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1448857:CCORG RS00440
gene id: 1448857:CCORG_RS00440
uniprot id: A0A7M1LJV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1448857:CCORG RS08285
gene id: 1448857:CCORG_RS08285
uniprot id: A0A7M1LHV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1448857:CCORG RS07565
gene id: 1448857:CCORG_RS07565
uniprot id: A0A7M1LI10
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1448857:CCORG RS07005
gene id: 1448857:CCORG_RS07005
uniprot id: A0A7M1LDU8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1448857:CCORG RS08220
gene id: 1448857:CCORG_RS08220
uniprot id: A0A7M1LJH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1448857:CCORG RS04380
gene id: 1448857:CCORG_RS04380
uniprot id: A0A7M1LEV6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1448857:CCORG RS06310
gene id: 1448857:CCORG_RS06310
uniprot id: A0A7M1LFB5
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS00855
gene id: 1448857:CCORG_RS00855
uniprot id: A0A7M1LHC3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

1448857:CCORG RS04605
gene id: 1448857:CCORG_RS04605
uniprot id: A0A7M1LES1
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1448857:CCORG RS01920
gene id: 1448857:CCORG_RS01920
uniprot id: A0A7M1LG31
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1448857:CCORG RS00425
gene id: 1448857:CCORG_RS00425
uniprot id: A0A7M1LGX9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1448857:CCORG RS04955
gene id: 1448857:CCORG_RS04955
uniprot id: A0A7M1LEY2
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1448857:CCORG RS00535
gene id: 1448857:CCORG_RS00535
uniprot id: A0A7M1LGS6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1448857:CCORG RS08405
gene id: 1448857:CCORG_RS08405
uniprot id: A0A7M1LHU2
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS00445
gene id: 1448857:CCORG_RS00445
uniprot id: A0A7M1LIN7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1448857:CCORG RS02185
gene id: 1448857:CCORG_RS02185
uniprot id: A0A7M1LGN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1448857:CCORG RS05090
gene id: 1448857:CCORG_RS05090
uniprot id: A0A7M1LHK3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1448857:CCORG RS05330
gene id: 1448857:CCORG_RS05330
uniprot id: A0A7M1LED0
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1448857:CCORG RS05525
gene id: 1448857:CCORG_RS05525
uniprot id: A0A7M1LE95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1448857:CCORG RS07220
gene id: 1448857:CCORG_RS07220
uniprot id: A0A7M1LE38
names: Similarity
messages: Belongs to the UPF0751 family.

1448857:CCORG RS02430
gene id: 1448857:CCORG_RS02430
uniprot id: A0A7M1LHV8
names: Similarity
messages: Belongs to the pyruvate kinase family.

1448857:CCORG RS01990
gene id: 1448857:CCORG_RS01990
uniprot id: A0A7M1LG44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1448857:CCORG RS01925
gene id: 1448857:CCORG_RS01925
uniprot id: A0A7M1LI44
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1448857:CCORG RS07480
gene id: 1448857:CCORG_RS07480
uniprot id: A0A7M1LKN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Membrane

1448857:CCORG RS06920
gene id: 1448857:CCORG_RS06920
uniprot id: A0A7M1LDL2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1448857:CCORG RS04830
gene id: 1448857:CCORG_RS04830
uniprot id: A0A7M1LHQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1448857:CCORG RS04460
gene id: 1448857:CCORG_RS04460
uniprot id: A0A7M1LGX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

1448857:CCORG RS01390
gene id: 1448857:CCORG_RS01390
uniprot id: A0A7M1LI36
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1448857:CCORG RS00140
gene id: 1448857:CCORG_RS00140
uniprot id: A0A7M1LGZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

1448857:CCORG RS05230
gene id: 1448857:CCORG_RS05230
uniprot id: A0A7M1LEE9
names: Similarity
messages: Belongs to the aspartokinase family.

1448857:CCORG RS04120
gene id: 1448857:CCORG_RS04120
uniprot id: A0A7M1LF33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1448857:CCORG RS03005
gene id: 1448857:CCORG_RS03005
uniprot id: A0A7M1LFM9
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS07510
gene id: 1448857:CCORG_RS07510
uniprot id: A0A7M1LHM2
names: Similarity
messages: Belongs to the alkaline phosphatase family.

1448857:CCORG RS00095
gene id: 1448857:CCORG_RS00095
uniprot id: A0A7M1LJ66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1448857:CCORG RS03105
gene id: 1448857:CCORG_RS03105
uniprot id: A0A7M1LG83
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1448857:CCORG RS05550
gene id: 1448857:CCORG_RS05550
uniprot id: A0A7M1LE81
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1448857:CCORG RS03240
gene id: 1448857:CCORG_RS03240
uniprot id: A0A7M1LG78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Hydrolyzes 6-aminopenicillinic acid and 7-aminocephalosporanic acid (ACA) derivatives.
messages: Secreted

1448857:CCORG RS00735
gene id: 1448857:CCORG_RS00735
uniprot id: A0A7M1LII1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1448857:CCORG RS04865
gene id: 1448857:CCORG_RS04865
uniprot id: A0A7M1LEP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1448857:CCORG RS03825
gene id: 1448857:CCORG_RS03825
uniprot id: A0A7M1LFX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1448857:CCORG RS00070
gene id: 1448857:CCORG_RS00070
uniprot id: A0A7M1LHS5
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1448857:CCORG RS02225
gene id: 1448857:CCORG_RS02225
uniprot id: A0A7M1LHZ8
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS06015
gene id: 1448857:CCORG_RS06015
uniprot id: A0A7M1LE05
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS05840
gene id: 1448857:CCORG_RS05840
uniprot id: A0A7M1LE60
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1448857:CCORG RS03010
gene id: 1448857:CCORG_RS03010
uniprot id: A0A7M1LFJ7
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS04375
gene id: 1448857:CCORG_RS04375
uniprot id: A0A7M1LFM8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1448857:CCORG RS00335
gene id: 1448857:CCORG_RS00335
uniprot id: A0A7M1LHL1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1448857:CCORG RS08370
gene id: 1448857:CCORG_RS08370
uniprot id: A0A7M1LH97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1448857:CCORG RS07200
gene id: 1448857:CCORG_RS07200
uniprot id: A0A7M1LGH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1448857:CCORG RS06805
gene id: 1448857:CCORG_RS06805
uniprot id: A0A7M1LGP8
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS03145
gene id: 1448857:CCORG_RS03145
uniprot id: A0A7M1LIB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1448857:CCORG RS07185
gene id: 1448857:CCORG_RS07185
uniprot id: A0A7M1LDI2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS06645
gene id: 1448857:CCORG_RS06645
uniprot id: A0A7M1LFL6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1448857:CCORG RS05715
gene id: 1448857:CCORG_RS05715
uniprot id: A0A7M1LEI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1448857:CCORG RS06810
gene id: 1448857:CCORG_RS06810
uniprot id: A0A7M1LF19
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

1448857:CCORG RS05250
gene id: 1448857:CCORG_RS05250
uniprot id: A0A7M1LHH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1448857:CCORG RS08280
gene id: 1448857:CCORG_RS08280
uniprot id: A0A7M1LJ40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1448857:CCORG RS08245
gene id: 1448857:CCORG_RS08245
uniprot id: A0A7M1LI03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1448857:CCORG RS00290
gene id: 1448857:CCORG_RS00290
uniprot id: A0A7M1LHP0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1448857:CCORG RS08350
gene id: 1448857:CCORG_RS08350
uniprot id: A0A7M1LHY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1448857:CCORG RS00635
gene id: 1448857:CCORG_RS00635
uniprot id: A0A7M1LHG3
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1448857:CCORG RS02030
gene id: 1448857:CCORG_RS02030
uniprot id: A0A7M1LGG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1448857:CCORG RS00610
gene id: 1448857:CCORG_RS00610
uniprot id: A0A7M1LGU9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1448857:CCORG RS06155
gene id: 1448857:CCORG_RS06155
uniprot id: A0A7M1LEL5
names: Subcellular Location Annotation
messages: Membrane

1448857:CCORG RS08200
gene id: 1448857:CCORG_RS08200
uniprot id: A0A7M1LHQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1448857:CCORG RS08340
gene id: 1448857:CCORG_RS08340
uniprot id: A0A7M1LHV0
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

1448857:CCORG RS05125
gene id: 1448857:CCORG_RS05125
uniprot id: A0A7M1LEH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane

1448857:CCORG RS06800
gene id: 1448857:CCORG_RS06800
uniprot id: A0A7M1LFI6
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

1448857:CCORG RS03715
gene id: 1448857:CCORG_RS03715
uniprot id: A0A7M1LFN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane

1448857:CCORG RS07770
gene id: 1448857:CCORG_RS07770
uniprot id: A0A7M1LI46
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1448857:CCORG RS01945
gene id: 1448857:CCORG_RS01945
uniprot id: A0A7M1LG28
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.