1437874:CSPHI RS07890
gene id: 1437874:CSPHI_RS07890
uniprot id: A0A1L7CYV2
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

1437874:CSPHI RS04525
gene id: 1437874:CSPHI_RS04525
uniprot id: A0A1L7CX47
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1437874:CSPHI RS07520
gene id: 1437874:CSPHI_RS07520
uniprot id: A0A1L7CYX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1437874:CSPHI RS02645
gene id: 1437874:CSPHI_RS02645
uniprot id: A0A1L7CWH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1437874:CSPHI RS00900
gene id: 1437874:CSPHI_RS00900
uniprot id: A0A1L7CVL6
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

1437874:CSPHI RS07300
gene id: 1437874:CSPHI_RS07300
uniprot id: A0A1L7CYJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1437874:CSPHI RS07950
gene id: 1437874:CSPHI_RS07950
uniprot id: A0A1L7CYW2
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1437874:CSPHI RS03080
gene id: 1437874:CSPHI_RS03080
uniprot id: A0A1L7CWN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Mmr subfamily.
messages: Cell membrane
messages: Membrane

1437874:CSPHI RS01735
gene id: 1437874:CSPHI_RS01735
uniprot id: A0A1L7CVV5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1437874:CSPHI RS11240
gene id: 1437874:CSPHI_RS11240
uniprot id: A0A1L7D077
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1437874:CSPHI RS07680
gene id: 1437874:CSPHI_RS07680
uniprot id: A0A1L7CYK0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1437874:CSPHI RS05175
gene id: 1437874:CSPHI_RS05175
uniprot id: A0A1L7CXL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1437874:CSPHI RS02135
gene id: 1437874:CSPHI_RS02135
uniprot id: A0A1L7CW17
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1437874:CSPHI RS07910
gene id: 1437874:CSPHI_RS07910
uniprot id: A0A1L7CYU1
names: Similarity
messages: Belongs to the glutamine synthetase family.

1437874:CSPHI RS07280
gene id: 1437874:CSPHI_RS07280
uniprot id: A0A1L7CYF6
names: Similarity
messages: Belongs to the TrpC family.

1437874:CSPHI RS07650
gene id: 1437874:CSPHI_RS07650
uniprot id: A0A1L7CYQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1437874:CSPHI RS00510
gene id: 1437874:CSPHI_RS00510
uniprot id: A0A1L7CVG5
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS02875
gene id: 1437874:CSPHI_RS02875
uniprot id: A0A1L7CWE0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1437874:CSPHI RS01830
gene id: 1437874:CSPHI_RS01830
uniprot id: A0A1L7CW44
names: Similarity
messages: Belongs to the WXG100 family.

1437874:CSPHI RS09985
gene id: 1437874:CSPHI_RS09985
uniprot id: A0A1L7CZQ6
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1437874:CSPHI RS10855
gene id: 1437874:CSPHI_RS10855
uniprot id: A0A1L7D042
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1437874:CSPHI RS09955
gene id: 1437874:CSPHI_RS09955
uniprot id: A0A1L7CZJ8
names: Similarity
messages: Belongs to the HypD family.

1437874:CSPHI RS02215
gene id: 1437874:CSPHI_RS02215
uniprot id: A0A1L7CW28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1437874:CSPHI RS10610
gene id: 1437874:CSPHI_RS10610
uniprot id: A0A1L7D016
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1437874:CSPHI RS09930
gene id: 1437874:CSPHI_RS09930
uniprot id: A0A1L7CZJ0
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1437874:CSPHI RS00015
gene id: 1437874:CSPHI_RS00015
uniprot id: A0A1L7CV55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1437874:CSPHI RS01290
gene id: 1437874:CSPHI_RS01290
uniprot id: A0A1L7CVN3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1437874:CSPHI RS10500
gene id: 1437874:CSPHI_RS10500
uniprot id: A0A1L7D0B4
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1437874:CSPHI RS04240
gene id: 1437874:CSPHI_RS04240
uniprot id: A0A1L7CX59
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1437874:CSPHI RS05915
gene id: 1437874:CSPHI_RS05915
uniprot id: A0A1L7CXY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1437874:CSPHI RS03935
gene id: 1437874:CSPHI_RS03935
uniprot id: A0A1L7CWW0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1437874:CSPHI RS12025
gene id: 1437874:CSPHI_RS12025
uniprot id: A0A1L7CXL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1437874:CSPHI RS05790
gene id: 1437874:CSPHI_RS05790
uniprot id: A0A1L7CY00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS07855
gene id: 1437874:CSPHI_RS07855
uniprot id: A0A1L7CYU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1437874:CSPHI RS10315
gene id: 1437874:CSPHI_RS10315
uniprot id: A0A1L7CZQ2
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1437874:CSPHI RS08360
gene id: 1437874:CSPHI_RS08360
uniprot id: A0A1L7CZ13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1437874:CSPHI RS08190
gene id: 1437874:CSPHI_RS08190
uniprot id: A0A1L7CYS5
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS01515
gene id: 1437874:CSPHI_RS01515
uniprot id: A0A1L7CVZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1437874:CSPHI RS09830
gene id: 1437874:CSPHI_RS09830
uniprot id: A0A1L7CZP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1437874:CSPHI RS07630
gene id: 1437874:CSPHI_RS07630
uniprot id: A0A1L7CYQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1437874:CSPHI RS08335
gene id: 1437874:CSPHI_RS08335
uniprot id: A0A1L7CZ11
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

1437874:CSPHI RS01965
gene id: 1437874:CSPHI_RS01965
uniprot id: A0A1L7CW61
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1437874:CSPHI RS11405
gene id: 1437874:CSPHI_RS11405
uniprot id: A0A1L7D0B9
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS00710
gene id: 1437874:CSPHI_RS00710
uniprot id: A0A1L7CVF8
names: Similarity
messages: Belongs to the catalase family.

1437874:CSPHI RS06405
gene id: 1437874:CSPHI_RS06405
uniprot id: A0A1L7CY70
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1437874:CSPHI RS07010
gene id: 1437874:CSPHI_RS07010
uniprot id: A0A1L7CYG2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1437874:CSPHI RS02880
gene id: 1437874:CSPHI_RS02880
uniprot id: A0A1L7CWD8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

1437874:CSPHI RS00095
gene id: 1437874:CSPHI_RS00095
uniprot id: A0A1L7CVC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

1437874:CSPHI RS09890
gene id: 1437874:CSPHI_RS09890
uniprot id: A0A1L7CZM0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1437874:CSPHI RS06725
gene id: 1437874:CSPHI_RS06725
uniprot id: A0A1L7CYC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1437874:CSPHI RS09975
gene id: 1437874:CSPHI_RS09975
uniprot id: A0A1L7CZU5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1437874:CSPHI RS05255
gene id: 1437874:CSPHI_RS05255
uniprot id: A0A1L7CXI2
names: Similarity
messages: Belongs to the MQO family.

1437874:CSPHI RS09995
gene id: 1437874:CSPHI_RS09995
uniprot id: A0A1L7CZK0
names: Similarity
messages: Belongs to the peptidase A31 family.

1437874:CSPHI RS00305
gene id: 1437874:CSPHI_RS00305
uniprot id: A0A1L7CVC6
names: Similarity
messages: Belongs to the glutamate synthase family.

1437874:CSPHI RS01365
gene id: 1437874:CSPHI_RS01365
uniprot id: A0A1L7CVQ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1437874:CSPHI RS04410
gene id: 1437874:CSPHI_RS04410
uniprot id: A0A1L7CXB7
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1437874:CSPHI RS05665
gene id: 1437874:CSPHI_RS05665
uniprot id: A0A1L7CXP0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1437874:CSPHI RS07820
gene id: 1437874:CSPHI_RS07820
uniprot id: A0A1L7CYT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

1437874:CSPHI RS05565
gene id: 1437874:CSPHI_RS05565
uniprot id: A0A1L7CXS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1437874:CSPHI RS04220
gene id: 1437874:CSPHI_RS04220
uniprot id: A0A1L7CX62
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1437874:CSPHI RS10080
gene id: 1437874:CSPHI_RS10080
uniprot id: A0A1L7CZL8
names: Similarity
messages: Belongs to the TPP enzyme family.

1437874:CSPHI RS02870
gene id: 1437874:CSPHI_RS02870
uniprot id: A0A1L7CWH8
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

1437874:CSPHI RS07560
gene id: 1437874:CSPHI_RS07560
uniprot id: A0A1L7CYI2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1437874:CSPHI RS10430
gene id: 1437874:CSPHI_RS10430
uniprot id: A0A1L7D0A6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1437874:CSPHI RS11735
gene id: 1437874:CSPHI_RS11735
uniprot id: A0A1L7D0G7
names: Similarity
messages: Belongs to the thioredoxin family.

1437874:CSPHI RS04385
gene id: 1437874:CSPHI_RS04385
uniprot id: A0A1L7CX85
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS03100
gene id: 1437874:CSPHI_RS03100
uniprot id: A0A1L7CWS1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1437874:CSPHI RS06885
gene id: 1437874:CSPHI_RS06885
uniprot id: A0A1L7CYD9
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1437874:CSPHI RS06605
gene id: 1437874:CSPHI_RS06605
uniprot id: A0A1L7CYC4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1437874:CSPHI RS05630
gene id: 1437874:CSPHI_RS05630
uniprot id: A0A1L7CXP2
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.

1437874:CSPHI RS02760
gene id: 1437874:CSPHI_RS02760
uniprot id: A0A1L7CWI8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1437874:CSPHI RS08000
gene id: 1437874:CSPHI_RS08000
uniprot id: A0A1L7CYV9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1437874:CSPHI RS01225
gene id: 1437874:CSPHI_RS01225
uniprot id: A0A1L7CVM6
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

1437874:CSPHI RS00085
gene id: 1437874:CSPHI_RS00085
uniprot id: A0A1L7D0C7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1437874:CSPHI RS09095
gene id: 1437874:CSPHI_RS09095
uniprot id: A0A1L7CZC3
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1437874:CSPHI RS02550
gene id: 1437874:CSPHI_RS02550
uniprot id: A0A1L7CWD0
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1437874:CSPHI RS11250
gene id: 1437874:CSPHI_RS11250
uniprot id: A0A1L7D027
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1437874:CSPHI RS05670
gene id: 1437874:CSPHI_RS05670
uniprot id: A0A1L7CXT7
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1437874:CSPHI RS01480
gene id: 1437874:CSPHI_RS01480
uniprot id: A0A1L7CVW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1437874:CSPHI RS04215
gene id: 1437874:CSPHI_RS04215
uniprot id: A0A1L7CX01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1437874:CSPHI RS01540
gene id: 1437874:CSPHI_RS01540
uniprot id: A0A1L7CVV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1437874:CSPHI RS01210
gene id: 1437874:CSPHI_RS01210
uniprot id: A0A1L7CVQ5
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS07995
gene id: 1437874:CSPHI_RS07995
uniprot id: A0A1L7CYP6
names: Similarity
messages: Belongs to the glutamine synthetase family.

1437874:CSPHI RS01300
gene id: 1437874:CSPHI_RS01300
uniprot id: A0A1L7CVW1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1437874:CSPHI RS02860
gene id: 1437874:CSPHI_RS02860
uniprot id: A0A1L7CWN3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1437874:CSPHI RS02125
gene id: 1437874:CSPHI_RS02125
uniprot id: A0A1L7CW56
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1437874:CSPHI RS11390
gene id: 1437874:CSPHI_RS11390
uniprot id: A0A1L7D0A0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1437874:CSPHI RS04490
gene id: 1437874:CSPHI_RS04490
uniprot id: A0A1L7CXC7
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1437874:CSPHI RS00980
gene id: 1437874:CSPHI_RS00980
uniprot id: A0A1L7CVJ2
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1437874:CSPHI RS06235
gene id: 1437874:CSPHI_RS06235
uniprot id: A0A1L7CY40
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS00860
gene id: 1437874:CSPHI_RS00860
uniprot id: A0A1L7CVI2
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS06085
gene id: 1437874:CSPHI_RS06085
uniprot id: A0A1L7CXZ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1437874:CSPHI RS01335
gene id: 1437874:CSPHI_RS01335
uniprot id: A0A1L7CVW6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1437874:CSPHI RS06125
gene id: 1437874:CSPHI_RS06125
uniprot id: A0A1L7CXW8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS10010
gene id: 1437874:CSPHI_RS10010
uniprot id: A0A1L7CZN6
names: Similarity
messages: Belongs to the HupF/HypC family.

1437874:CSPHI RS09300
gene id: 1437874:CSPHI_RS09300
uniprot id: A0A1L7CZF2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1437874:CSPHI RS04510
gene id: 1437874:CSPHI_RS04510
uniprot id: A0A1L7CX48
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1437874:CSPHI RS06335
gene id: 1437874:CSPHI_RS06335
uniprot id: A0A1L7CY03
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

1437874:CSPHI RS06200
gene id: 1437874:CSPHI_RS06200
uniprot id: A0A1L7CY16
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1437874:CSPHI RS06610
gene id: 1437874:CSPHI_RS06610
uniprot id: A0A1L7CY97
names: Similarity
messages: Belongs to the CobH/CbiC family.

1437874:CSPHI RS01465
gene id: 1437874:CSPHI_RS01465
uniprot id: A0A1L7CVY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1437874:CSPHI RS02820
gene id: 1437874:CSPHI_RS02820
uniprot id: A0A1L7CWJ0
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

1437874:CSPHI RS03385
gene id: 1437874:CSPHI_RS03385
uniprot id: A0A1L7CWT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1437874:CSPHI RS06505
gene id: 1437874:CSPHI_RS06505
uniprot id: A0A1L7CY79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

1437874:CSPHI RS01475
gene id: 1437874:CSPHI_RS01475
uniprot id: A0A1L7CVU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1437874:CSPHI RS06820
gene id: 1437874:CSPHI_RS06820
uniprot id: A0A1L7CYD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1437874:CSPHI RS06495
gene id: 1437874:CSPHI_RS06495
uniprot id: A0A1L7CY84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

1437874:CSPHI RS08445
gene id: 1437874:CSPHI_RS08445
uniprot id: A0A1L7CZB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1437874:CSPHI RS06570
gene id: 1437874:CSPHI_RS06570
uniprot id: A0A1L7CY43
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1437874:CSPHI RS11370
gene id: 1437874:CSPHI_RS11370
uniprot id: A0A1L7D0C3
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

1437874:CSPHI RS04265
gene id: 1437874:CSPHI_RS04265
uniprot id: A0A1L7CWZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1437874:CSPHI RS07270
gene id: 1437874:CSPHI_RS07270
uniprot id: A0A1L7CYK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1437874:CSPHI RS05190
gene id: 1437874:CSPHI_RS05190
uniprot id: A0A1L7CXJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1437874:CSPHI RS03925
gene id: 1437874:CSPHI_RS03925
uniprot id: A0A1L7CX24
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS06665
gene id: 1437874:CSPHI_RS06665
uniprot id: A0A1L7CYE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1437874:CSPHI RS04310
gene id: 1437874:CSPHI_RS04310
uniprot id: A0A1L7CX45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

1437874:CSPHI RS00865
gene id: 1437874:CSPHI_RS00865
uniprot id: A0A1L7CVP4
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS04325
gene id: 1437874:CSPHI_RS04325
uniprot id: A0A1L7CX78
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1437874:CSPHI RS03490
gene id: 1437874:CSPHI_RS03490
uniprot id: A0A1L7CWR3
names: Similarity
messages: Belongs to the peptidase C56 family.

1437874:CSPHI RS06450
gene id: 1437874:CSPHI_RS06450
uniprot id: A0A1L7CY68
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1437874:CSPHI RS01665
gene id: 1437874:CSPHI_RS01665
uniprot id: A0A1L7CVY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1437874:CSPHI RS01745
gene id: 1437874:CSPHI_RS01745
uniprot id: A0A1L7CW30
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS07600
gene id: 1437874:CSPHI_RS07600
uniprot id: A0A1L7CYP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

1437874:CSPHI RS09745
gene id: 1437874:CSPHI_RS09745
uniprot id: A0A1L7CZM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1437874:CSPHI RS07775
gene id: 1437874:CSPHI_RS07775
uniprot id: A0A1L7CYT1
names: Similarity
messages: Belongs to the peptidase C40 family.

1437874:CSPHI RS03365
gene id: 1437874:CSPHI_RS03365
uniprot id: A0A1L7CWM4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1437874:CSPHI RS02400
gene id: 1437874:CSPHI_RS02400
uniprot id: A0A1L7CWC3
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1437874:CSPHI RS02410
gene id: 1437874:CSPHI_RS02410
uniprot id: A0A1L7CW78
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1437874:CSPHI RS07150
gene id: 1437874:CSPHI_RS07150
uniprot id: A0A1L7CYJ0
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1437874:CSPHI RS06705
gene id: 1437874:CSPHI_RS06705
uniprot id: A0A1L7CYA5
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1437874:CSPHI RS09965
gene id: 1437874:CSPHI_RS09965
uniprot id: A0A1L7CZZ0
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

1437874:CSPHI RS06145
gene id: 1437874:CSPHI_RS06145
uniprot id: A0A1L7CY04
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1437874:CSPHI RS07225
gene id: 1437874:CSPHI_RS07225
uniprot id: A0A1L7CYI7
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS06560
gene id: 1437874:CSPHI_RS06560
uniprot id: A0A1L7CY90
names: Similarity
messages: Belongs to the peptidase M24B family.

1437874:CSPHI RS09575
gene id: 1437874:CSPHI_RS09575
uniprot id: A0A1L7CZN4
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1437874:CSPHI RS03070
gene id: 1437874:CSPHI_RS03070
uniprot id: A0A1L7CWN0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1437874:CSPHI RS02065
gene id: 1437874:CSPHI_RS02065
uniprot id: A0A1L7CW08
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS05275
gene id: 1437874:CSPHI_RS05275
uniprot id: A0A1L7CXN4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1437874:CSPHI RS06155
gene id: 1437874:CSPHI_RS06155
uniprot id: A0A1L7CY28
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1437874:CSPHI RS05305
gene id: 1437874:CSPHI_RS05305
uniprot id: A0A1L7CXP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1437874:CSPHI RS04235
gene id: 1437874:CSPHI_RS04235
uniprot id: A0A1L7CX53
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS03255
gene id: 1437874:CSPHI_RS03255
uniprot id: A0A1L7CWK1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1437874:CSPHI RS00970
gene id: 1437874:CSPHI_RS00970
uniprot id: A0A1L7CVN4
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1437874:CSPHI RS10630
gene id: 1437874:CSPHI_RS10630
uniprot id: A0A1L7D0D4
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS11775
gene id: 1437874:CSPHI_RS11775
uniprot id: A0A1L7D0F9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1437874:CSPHI RS08890
gene id: 1437874:CSPHI_RS08890
uniprot id: A0A1L7CZ24
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1437874:CSPHI RS01420
gene id: 1437874:CSPHI_RS01420
uniprot id: A0A1L7CVR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1437874:CSPHI RS11150
gene id: 1437874:CSPHI_RS11150
uniprot id: A0A1L7D021
names: Similarity
messages: Belongs to the universal stress protein A family.

1437874:CSPHI RS02345
gene id: 1437874:CSPHI_RS02345
uniprot id: A0A1L7CWB1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1437874:CSPHI RS00995
gene id: 1437874:CSPHI_RS00995
uniprot id: A0A1L7CVR4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1437874:CSPHI RS08060
gene id: 1437874:CSPHI_RS08060
uniprot id: A0A1L7CYW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1437874:CSPHI RS05975
gene id: 1437874:CSPHI_RS05975
uniprot id: A0A1L7CXU0
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1437874:CSPHI RS05905
gene id: 1437874:CSPHI_RS05905
uniprot id: A0A1L7CXT9
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1437874:CSPHI RS08935
gene id: 1437874:CSPHI_RS08935
uniprot id: A0A1L7CZ93
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1437874:CSPHI RS06775
gene id: 1437874:CSPHI_RS06775
uniprot id: A0A1L7CYC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1437874:CSPHI RS03200
gene id: 1437874:CSPHI_RS03200
uniprot id: A0A1L7CWI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1437874:CSPHI RS05145
gene id: 1437874:CSPHI_RS05145
uniprot id: A0A1L7CXG3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1437874:CSPHI RS09780
gene id: 1437874:CSPHI_RS09780
uniprot id: A0A1L7CZR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1437874:CSPHI RS07660
gene id: 1437874:CSPHI_RS07660
uniprot id: A0A1L7CYQ8
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS05445
gene id: 1437874:CSPHI_RS05445
uniprot id: A0A1L7CXQ6
names: Similarity
messages: Belongs to the PspA/IM30 family.

1437874:CSPHI RS00990
gene id: 1437874:CSPHI_RS00990
uniprot id: A0A1L7CVR1
names: Cofactor
messages: Can also use Mn(2+) ion.

1437874:CSPHI RS01605
gene id: 1437874:CSPHI_RS01605
uniprot id: A0A1L7CVT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1437874:CSPHI RS10510
gene id: 1437874:CSPHI_RS10510
uniprot id: A0A1L7D020
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1437874:CSPHI RS10695
gene id: 1437874:CSPHI_RS10695
uniprot id: A0A1L7CZY5
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1437874:CSPHI RS08390
gene id: 1437874:CSPHI_RS08390
uniprot id: A0A1L7CZA2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1437874:CSPHI RS00500
gene id: 1437874:CSPHI_RS00500
uniprot id: A0A1L7CVF4
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1437874:CSPHI RS07000
gene id: 1437874:CSPHI_RS07000
uniprot id: A0A1L7CYF5
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1437874:CSPHI RS07350
gene id: 1437874:CSPHI_RS07350
uniprot id: A0A1L7CYF8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1437874:CSPHI RS00460
gene id: 1437874:CSPHI_RS00460
uniprot id: A0A1L7CVC0
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1437874:CSPHI RS06195
gene id: 1437874:CSPHI_RS06195
uniprot id: A0A1L7CXW9
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1437874:CSPHI RS06250
gene id: 1437874:CSPHI_RS06250
uniprot id: A0A1L7CY25
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1437874:CSPHI RS02260
gene id: 1437874:CSPHI_RS02260
uniprot id: A0A1L7CWC4
names: Function
messages: This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser.

1437874:CSPHI RS06025
gene id: 1437874:CSPHI_RS06025
uniprot id: A0A1L7CY02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1437874:CSPHI RS09075
gene id: 1437874:CSPHI_RS09075
uniprot id: A0A1L7CZ56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1437874:CSPHI RS05380
gene id: 1437874:CSPHI_RS05380
uniprot id: A0A1L7CXQ7
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

1437874:CSPHI RS02965
gene id: 1437874:CSPHI_RS02965
uniprot id: A0A1L7CWM5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1437874:CSPHI RS08285
gene id: 1437874:CSPHI_RS08285
uniprot id: A0A1L7CYT8
names: Subcellular Location Annotation
messages: Secreted

1437874:CSPHI RS11720
gene id: 1437874:CSPHI_RS11720
uniprot id: A0A1L7D0B8
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS05855
gene id: 1437874:CSPHI_RS05855
uniprot id: A0A1L7CXX4
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

1437874:CSPHI RS02940
gene id: 1437874:CSPHI_RS02940
uniprot id: A0A1L7CWL3
names: Similarity
messages: Belongs to the peptidase S58 family.

1437874:CSPHI RS08680
gene id: 1437874:CSPHI_RS08680
uniprot id: A0A1L7CZ55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1437874:CSPHI RS04435
gene id: 1437874:CSPHI_RS04435
uniprot id: A0A1L7CX98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS05795
gene id: 1437874:CSPHI_RS05795
uniprot id: A0A1L7CXX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1437874:CSPHI RS04660
gene id: 1437874:CSPHI_RS04660
uniprot id: A0A1L7CX63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1437874:CSPHI RS09435
gene id: 1437874:CSPHI_RS09435
uniprot id: A0A1L7CZH4
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS05225
gene id: 1437874:CSPHI_RS05225
uniprot id: A0A1L7CXM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1437874:CSPHI RS04280
gene id: 1437874:CSPHI_RS04280
uniprot id: A0A1L7CX66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1437874:CSPHI RS05930
gene id: 1437874:CSPHI_RS05930
uniprot id: A0A1L7CXW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1437874:CSPHI RS07745
gene id: 1437874:CSPHI_RS07745
uniprot id: A0A1L7CYS3
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
messages: Homodimer.

1437874:CSPHI RS11060
gene id: 1437874:CSPHI_RS11060
uniprot id: A0A1L7D057
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1437874:CSPHI RS08405
gene id: 1437874:CSPHI_RS08405
uniprot id: A0A1L7CZ61
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1437874:CSPHI RS08815
gene id: 1437874:CSPHI_RS08815
uniprot id: A0A1L7CZ14
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1437874:CSPHI RS05300
gene id: 1437874:CSPHI_RS05300
uniprot id: A0A1L7CXM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1437874:CSPHI RS05280
gene id: 1437874:CSPHI_RS05280
uniprot id: A0A1L7CXM9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1437874:CSPHI RS06080
gene id: 1437874:CSPHI_RS06080
uniprot id: A0A1L7CY08
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1437874:CSPHI RS07310
gene id: 1437874:CSPHI_RS07310
uniprot id: A0A1L7CYK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1437874:CSPHI RS02130
gene id: 1437874:CSPHI_RS02130
uniprot id: A0A1L7CW12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1437874:CSPHI RS05010
gene id: 1437874:CSPHI_RS05010
uniprot id: A0A1L7CXE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1437874:CSPHI RS02735
gene id: 1437874:CSPHI_RS02735
uniprot id: A0A1L7CWL4
names: Similarity
messages: Belongs to the DEAD box helicase family.

1437874:CSPHI RS02160
gene id: 1437874:CSPHI_RS02160
uniprot id: A0A1L7CW38
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1437874:CSPHI RS08770
gene id: 1437874:CSPHI_RS08770
uniprot id: A0A1L7CZ12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

1437874:CSPHI RS05635
gene id: 1437874:CSPHI_RS05635
uniprot id: A0A1L7CXP3
names: Subcellular Location Annotation
messages: Cytoplasm

1437874:CSPHI RS00115
gene id: 1437874:CSPHI_RS00115
uniprot id: A0A1L7CVE3
names: Similarity
messages: Belongs to the class-D beta-lactamase family.

1437874:CSPHI RS10460
gene id: 1437874:CSPHI_RS10460
uniprot id: A0A1L7CZX7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1437874:CSPHI RS10745
gene id: 1437874:CSPHI_RS10745
uniprot id: A0A1L7D014
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1437874:CSPHI RS11095
gene id: 1437874:CSPHI_RS11095
uniprot id: A0A1L7D0B6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1437874:CSPHI RS03220
gene id: 1437874:CSPHI_RS03220
uniprot id: A0A1L7CWJ9
names: Caution
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS07445
gene id: 1437874:CSPHI_RS07445
uniprot id: A0A1L7CYM1
names: Similarity
messages: Belongs to the HSP15 family.

1437874:CSPHI RS07710
gene id: 1437874:CSPHI_RS07710
uniprot id: A0A1L7CYR4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1437874:CSPHI RS02220
gene id: 1437874:CSPHI_RS02220
uniprot id: A0A1L7CW97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

1437874:CSPHI RS02300
gene id: 1437874:CSPHI_RS02300
uniprot id: A0A1L7CW58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1437874:CSPHI RS06640
gene id: 1437874:CSPHI_RS06640
uniprot id: A0A1L7CYA6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS02205
gene id: 1437874:CSPHI_RS02205
uniprot id: A0A1L7CW66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437874:CSPHI RS09555
gene id: 1437874:CSPHI_RS09555
uniprot id: A0A1L7CZE1
names: Similarity
messages: Belongs to the citrate synthase family.

1437874:CSPHI RS09660
gene id: 1437874:CSPHI_RS09660
uniprot id: A0A1L7CZK9
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1437874:CSPHI RS00530
gene id: 1437874:CSPHI_RS00530
uniprot id: A0A1L7CVI8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

1437874:CSPHI RS00705
gene id: 1437874:CSPHI_RS00705
uniprot id: A0A1L7CVK0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1437874:CSPHI RS01345
gene id: 1437874:CSPHI_RS01345
uniprot id: A0A1L7CVY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1437874:CSPHI RS06975
gene id: 1437874:CSPHI_RS06975
uniprot id: A0A1L7CYA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1437874:CSPHI RS10930
gene id: 1437874:CSPHI_RS10930
uniprot id: A0A1L7D0H2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1437874:CSPHI RS07320
gene id: 1437874:CSPHI_RS07320
uniprot id: A0A1L7CYL0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1437874:CSPHI RS05995
gene id: 1437874:CSPHI_RS05995
uniprot id: A0A1L7CXZ8
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS05550
gene id: 1437874:CSPHI_RS05550
uniprot id: A0A1L7CXS5
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1437874:CSPHI RS02305
gene id: 1437874:CSPHI_RS02305
uniprot id: A0A1L7CWB7
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1437874:CSPHI RS10995
gene id: 1437874:CSPHI_RS10995
uniprot id: A0A1L7D000
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1437874:CSPHI RS06170
gene id: 1437874:CSPHI_RS06170
uniprot id: A0A1L7CY17
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1437874:CSPHI RS09370
gene id: 1437874:CSPHI_RS09370
uniprot id: A0A1L7CZG4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS04425
gene id: 1437874:CSPHI_RS04425
uniprot id: A0A1L7CX27
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1437874:CSPHI RS04595
gene id: 1437874:CSPHI_RS04595
uniprot id: A0A1L7CXB6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1437874:CSPHI RS10375
gene id: 1437874:CSPHI_RS10375
uniprot id: A0A1L7CZW3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1437874:CSPHI RS09680
gene id: 1437874:CSPHI_RS09680
uniprot id: A0A1L7CZL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1437874:CSPHI RS03250
gene id: 1437874:CSPHI_RS03250
uniprot id: A0A1L7CWK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1437874:CSPHI RS03190
gene id: 1437874:CSPHI_RS03190
uniprot id: A0A1L7CWM7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1437874:CSPHI RS05080
gene id: 1437874:CSPHI_RS05080
uniprot id: A0A1L7CXG0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1437874:CSPHI RS07605
gene id: 1437874:CSPHI_RS07605
uniprot id: A0A1L7CYT5
names: Similarity
messages: Belongs to the YggT family.

1437874:CSPHI RS08425
gene id: 1437874:CSPHI_RS08425
uniprot id: A0A1L7CZ22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1437874:CSPHI RS04520
gene id: 1437874:CSPHI_RS04520
uniprot id: A0A1L7CXA4
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

1437874:CSPHI RS00915
gene id: 1437874:CSPHI_RS00915
uniprot id: A0A1L7CVI5
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS06225
gene id: 1437874:CSPHI_RS06225
uniprot id: A0A1L7CXY1
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1437874:CSPHI RS07340
gene id: 1437874:CSPHI_RS07340
uniprot id: A0A1L7CYG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1437874:CSPHI RS02795
gene id: 1437874:CSPHI_RS02795
uniprot id: A0A1L7CWG8
names: Similarity
messages: Belongs to the peptidase S16 family.

1437874:CSPHI RS08960
gene id: 1437874:CSPHI_RS08960
uniprot id: A0A1L7CZ46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1437874:CSPHI RS08685
gene id: 1437874:CSPHI_RS08685
uniprot id: A0A1L7CZ02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1437874:CSPHI RS05060
gene id: 1437874:CSPHI_RS05060
uniprot id: A0A1L7CXI6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1437874:CSPHI RS07380
gene id: 1437874:CSPHI_RS07380
uniprot id: A0A1L7CYF7
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1437874:CSPHI RS01330
gene id: 1437874:CSPHI_RS01330
uniprot id: A0A1L7CVQ8
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1437874:CSPHI RS10205
gene id: 1437874:CSPHI_RS10205
uniprot id: A0A1L7CZN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1437874:CSPHI RS01360
gene id: 1437874:CSPHI_RS01360
uniprot id: A0A1L7CVP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1437874:CSPHI RS09485
gene id: 1437874:CSPHI_RS09485
uniprot id: A0A1L7CZG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1437874:CSPHI RS10775
gene id: 1437874:CSPHI_RS10775
uniprot id: A0A1L7CZW7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1437874:CSPHI RS06455
gene id: 1437874:CSPHI_RS06455
uniprot id: A0A1L7CY21
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

1437874:CSPHI RS10530
gene id: 1437874:CSPHI_RS10530
uniprot id: A0A1L7CZY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1437874:CSPHI RS02280
gene id: 1437874:CSPHI_RS02280
uniprot id: A0A1L7CW34
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1437874:CSPHI RS10215
gene id: 1437874:CSPHI_RS10215
uniprot id: A0A1L7D032
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1437874:CSPHI RS05950
gene id: 1437874:CSPHI_RS05950
uniprot id: A0A1L7CXX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1437874:CSPHI RS03560
gene id: 1437874:CSPHI_RS03560
uniprot id: A0A1L7CWQ0
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1437874:CSPHI RS05400
gene id: 1437874:CSPHI_RS05400
uniprot id: A0A1L7CXP9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

1437874:CSPHI RS01020
gene id: 1437874:CSPHI_RS01020
uniprot id: A0A1L7CVN2
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1437874:CSPHI RS09690
gene id: 1437874:CSPHI_RS09690
uniprot id: A0A1L7CZM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1437874:CSPHI RS01500
gene id: 1437874:CSPHI_RS01500
uniprot id: A0A1L7CVY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1437874:CSPHI RS01670
gene id: 1437874:CSPHI_RS01670
uniprot id: A0A1L7CVU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1437874:CSPHI RS09375
gene id: 1437874:CSPHI_RS09375
uniprot id: A0A1L7CZQ0
names: Similarity
messages: Belongs to the UPF0371 family.

1437874:CSPHI RS11750
gene id: 1437874:CSPHI_RS11750
uniprot id: A0A1L7D0L1
names: Similarity
messages: Belongs to the ParB family.

1437874:CSPHI RS03665
gene id: 1437874:CSPHI_RS03665
uniprot id: A0A1L7CWY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1437874:CSPHI RS04290
gene id: 1437874:CSPHI_RS04290
uniprot id: A0A1L7CX58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1437874:CSPHI RS08180
gene id: 1437874:CSPHI_RS08180
uniprot id: A0A1L7CYS8
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS09325
gene id: 1437874:CSPHI_RS09325
uniprot id: A0A1L7CZG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1437874:CSPHI RS11560
gene id: 1437874:CSPHI_RS11560
uniprot id: A0A1L7D070
names: Similarity
messages: Belongs to the universal stress protein A family.

1437874:CSPHI RS10990
gene id: 1437874:CSPHI_RS10990
uniprot id: A0A1L7D024
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1437874:CSPHI RS04140
gene id: 1437874:CSPHI_RS04140
uniprot id: A0A1L7CX06
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1437874:CSPHI RS01080
gene id: 1437874:CSPHI_RS01080
uniprot id: A0A1L7CVP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

1437874:CSPHI RS00735
gene id: 1437874:CSPHI_RS00735
uniprot id: A0A1L7CVM4
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS02175
gene id: 1437874:CSPHI_RS02175
uniprot id: A0A1L7CW99
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1437874:CSPHI RS09935
gene id: 1437874:CSPHI_RS09935
uniprot id: A0A1L7CZI4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1437874:CSPHI RS02450
gene id: 1437874:CSPHI_RS02450
uniprot id: A0A1L7CW65
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS01350
gene id: 1437874:CSPHI_RS01350
uniprot id: A0A1L7CVS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1437874:CSPHI RS07860
gene id: 1437874:CSPHI_RS07860
uniprot id: A0A1L7CYS9
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1437874:CSPHI RS07880
gene id: 1437874:CSPHI_RS07880
uniprot id: A0A1L7CYU9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1437874:CSPHI RS08065
gene id: 1437874:CSPHI_RS08065
uniprot id: A0A1L7CYQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1437874:CSPHI RS04295
gene id: 1437874:CSPHI_RS04295
uniprot id: A0A1L7CX68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1437874:CSPHI RS07655
gene id: 1437874:CSPHI_RS07655
uniprot id: A0A1L7CYZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1437874:CSPHI RS03955
gene id: 1437874:CSPHI_RS03955
uniprot id: A0A1L7CX14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1437874:CSPHI RS11610
gene id: 1437874:CSPHI_RS11610
uniprot id: A0A1L7D0J2
names: Similarity
messages: Belongs to the PspA/IM30 family.

1437874:CSPHI RS06805
gene id: 1437874:CSPHI_RS06805
uniprot id: A0A1L7CYB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1437874:CSPHI RS06735
gene id: 1437874:CSPHI_RS06735
uniprot id: A0A1L7CYE5
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS06970
gene id: 1437874:CSPHI_RS06970
uniprot id: A0A1L7CYF3
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1437874:CSPHI RS05025
gene id: 1437874:CSPHI_RS05025
uniprot id: A0A1L7CXC6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1437874:CSPHI RS03195
gene id: 1437874:CSPHI_RS03195
uniprot id: A0A1L7CWJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1437874:CSPHI RS11765
gene id: 1437874:CSPHI_RS11765
uniprot id: A0A1L7D0A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1437874:CSPHI RS03775
gene id: 1437874:CSPHI_RS03775
uniprot id: A0A1L7CWT6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1437874:CSPHI RS00595
gene id: 1437874:CSPHI_RS00595
uniprot id: A0A1L7CVE2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1437874:CSPHI RS04500
gene id: 1437874:CSPHI_RS04500
uniprot id: A0A1L7CX75
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS07295
gene id: 1437874:CSPHI_RS07295
uniprot id: A0A1L7CYK3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1437874:CSPHI RS10785
gene id: 1437874:CSPHI_RS10785
uniprot id: A0A1L7D036
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

1437874:CSPHI RS06190
gene id: 1437874:CSPHI_RS06190
uniprot id: A0A1L7CY18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1437874:CSPHI RS11680
gene id: 1437874:CSPHI_RS11680
uniprot id: A0A1L7D0K2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS06140
gene id: 1437874:CSPHI_RS06140
uniprot id: A0A1L7CXW2
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1437874:CSPHI RS09205
gene id: 1437874:CSPHI_RS09205
uniprot id: A0A1L7CZ84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1437874:CSPHI RS04495
gene id: 1437874:CSPHI_RS04495
uniprot id: A0A1L7CX64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1437874:CSPHI RS11110
gene id: 1437874:CSPHI_RS11110
uniprot id: A0A1L7D061
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437874:CSPHI RS11270
gene id: 1437874:CSPHI_RS11270
uniprot id: A0A1L7D060
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS02370
gene id: 1437874:CSPHI_RS02370
uniprot id: A0A1L7CWE3
names: Similarity
messages: Belongs to the peptidase C40 family.

1437874:CSPHI RS06065
gene id: 1437874:CSPHI_RS06065
uniprot id: A0A1L7CXV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1437874:CSPHI RS01220
gene id: 1437874:CSPHI_RS01220
uniprot id: A0A1L7CVS5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1437874:CSPHI RS02540
gene id: 1437874:CSPHI_RS02540
uniprot id: A0A1L7CWH5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1437874:CSPHI RS03210
gene id: 1437874:CSPHI_RS03210
uniprot id: A0A1L7CWR4
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1437874:CSPHI RS01535
gene id: 1437874:CSPHI_RS01535
uniprot id: A0A1L7CW13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1437874:CSPHI RS11700
gene id: 1437874:CSPHI_RS11700
uniprot id: A0A1L7D092
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1437874:CSPHI RS05870
gene id: 1437874:CSPHI_RS05870
uniprot id: A0A1L7CXR9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS05775
gene id: 1437874:CSPHI_RS05775
uniprot id: A0A1L7CXV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1437874:CSPHI RS08980
gene id: 1437874:CSPHI_RS08980
uniprot id: A0A1L7CZB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1437874:CSPHI RS06210
gene id: 1437874:CSPHI_RS06210
uniprot id: A0A1L7CY36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1437874:CSPHI RS00515
gene id: 1437874:CSPHI_RS00515
uniprot id: A0A1L7CVC2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS04675
gene id: 1437874:CSPHI_RS04675
uniprot id: A0A1L7CXC5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1437874:CSPHI RS06240
gene id: 1437874:CSPHI_RS06240
uniprot id: A0A1L7CY31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1437874:CSPHI RS04690
gene id: 1437874:CSPHI_RS04690
uniprot id: A0A1L7CXD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1437874:CSPHI RS02320
gene id: 1437874:CSPHI_RS02320
uniprot id: A0A1L7CW77
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1437874:CSPHI RS05920
gene id: 1437874:CSPHI_RS05920
uniprot id: A0A1L7CXX0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1437874:CSPHI RS02865
gene id: 1437874:CSPHI_RS02865
uniprot id: A0A1L7CWG5
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

1437874:CSPHI RS07485
gene id: 1437874:CSPHI_RS07485
uniprot id: A0A1L7CYH3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1437874:CSPHI RS08340
gene id: 1437874:CSPHI_RS08340
uniprot id: A0A1L7CZ49
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1437874:CSPHI RS07260
gene id: 1437874:CSPHI_RS07260
uniprot id: A0A1L7CYN5
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

1437874:CSPHI RS03880
gene id: 1437874:CSPHI_RS03880
uniprot id: A0A1L7CX38
names: Similarity
messages: Belongs to the LOG family.

1437874:CSPHI RS05000
gene id: 1437874:CSPHI_RS05000
uniprot id: A0A1L7CXI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1437874:CSPHI RS00635
gene id: 1437874:CSPHI_RS00635
uniprot id: A0A1L7CVE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1437874:CSPHI RS07645
gene id: 1437874:CSPHI_RS07645
uniprot id: A0A1L7CYI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1437874:CSPHI RS07415
gene id: 1437874:CSPHI_RS07415
uniprot id: A0A1L7CYH4
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

1437874:CSPHI RS09355
gene id: 1437874:CSPHI_RS09355
uniprot id: A0A1L7CZG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437874:CSPHI RS04375
gene id: 1437874:CSPHI_RS04375
uniprot id: A0A1L7CX31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1437874:CSPHI RS07030
gene id: 1437874:CSPHI_RS07030
uniprot id: A0A1L7CYB5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1437874:CSPHI RS05355
gene id: 1437874:CSPHI_RS05355
uniprot id: A0A1L7CXR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1437874:CSPHI RS07005
gene id: 1437874:CSPHI_RS07005
uniprot id: A0A1L7CYN9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1437874:CSPHI RS09260
gene id: 1437874:CSPHI_RS09260
uniprot id: A0A1L7CZF3
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1437874:CSPHI RS07315
gene id: 1437874:CSPHI_RS07315
uniprot id: A0A1L7CYU3
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1437874:CSPHI RS08765
gene id: 1437874:CSPHI_RS08765
uniprot id: A0A1L7CZ50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1437874:CSPHI RS08800
gene id: 1437874:CSPHI_RS08800
uniprot id: A0A1L7CZB8
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1437874:CSPHI RS06980
gene id: 1437874:CSPHI_RS06980
uniprot id: A0A1L7CYA7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1437874:CSPHI RS01825
gene id: 1437874:CSPHI_RS01825
uniprot id: A0A1L7CVY2
names: Similarity
messages: Belongs to the WXG100 family.

1437874:CSPHI RS00365
gene id: 1437874:CSPHI_RS00365
uniprot id: A0A1L7CVD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 85 family.
messages: Cell membrane
messages: Membrane

1437874:CSPHI RS01660
gene id: 1437874:CSPHI_RS01660
uniprot id: A0A1L7CVX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1437874:CSPHI RS06810
gene id: 1437874:CSPHI_RS06810
uniprot id: A0A1L7CYF9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1437874:CSPHI RS03545
gene id: 1437874:CSPHI_RS03545
uniprot id: A0A1L7CWZ2
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

1437874:CSPHI RS06295
gene id: 1437874:CSPHI_RS06295
uniprot id: A0A1L7CXY5
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1437874:CSPHI RS03855
gene id: 1437874:CSPHI_RS03855
uniprot id: A0A1L7CWU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

1437874:CSPHI RS07780
gene id: 1437874:CSPHI_RS07780
uniprot id: A0A1L7CYW6
names: Similarity
messages: Belongs to the peptidase C40 family.

1437874:CSPHI RS07145
gene id: 1437874:CSPHI_RS07145
uniprot id: A0A1L7CYD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1437874:CSPHI RS05820
gene id: 1437874:CSPHI_RS05820
uniprot id: A0A1L7CXS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1437874:CSPHI RS05240
gene id: 1437874:CSPHI_RS05240
uniprot id: A0A1L7CXL0
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1437874:CSPHI RS03120
gene id: 1437874:CSPHI_RS03120
uniprot id: A0A1L7CWH9
names: Similarity
messages: Belongs to the peptidase M1 family.

1437874:CSPHI RS00890
gene id: 1437874:CSPHI_RS00890
uniprot id: A0A1L7CVQ7
names: Subcellular Location Annotation
messages: Cytoplasm

1437874:CSPHI RS05020
gene id: 1437874:CSPHI_RS05020
uniprot id: A0A1L7CXF0
names: Similarity
messages: Belongs to the acylphosphatase family.

1437874:CSPHI RS10160
gene id: 1437874:CSPHI_RS10160
uniprot id: A0A1L7CZT7
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

1437874:CSPHI RS01230
gene id: 1437874:CSPHI_RS01230
uniprot id: A0A1L7CVN0
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1437874:CSPHI RS03505
gene id: 1437874:CSPHI_RS03505
uniprot id: A0A1L7CWP0
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS06290
gene id: 1437874:CSPHI_RS06290
uniprot id: A0A1L7CY42
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1437874:CSPHI RS01840
gene id: 1437874:CSPHI_RS01840
uniprot id: A0A1L7CW63
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1437874:CSPHI RS07420
gene id: 1437874:CSPHI_RS07420
uniprot id: A0A1L7CYG6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1437874:CSPHI RS06045
gene id: 1437874:CSPHI_RS06045
uniprot id: A0A1L7CY39
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1437874:CSPHI RS10900
gene id: 1437874:CSPHI_RS10900
uniprot id: A0A1L7CZY0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1437874:CSPHI RS09440
gene id: 1437874:CSPHI_RS09440
uniprot id: A0A1L7CZR1
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1437874:CSPHI RS03305
gene id: 1437874:CSPHI_RS03305
uniprot id: A0A1L7CWL1
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1437874:CSPHI RS07550
gene id: 1437874:CSPHI_RS07550
uniprot id: A0A1L7CYJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1437874:CSPHI RS00760
gene id: 1437874:CSPHI_RS00760
uniprot id: A0A1L7CVN6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1437874:CSPHI RS04370
gene id: 1437874:CSPHI_RS04370
uniprot id: A0A1L7CX17
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1437874:CSPHI RS09895
gene id: 1437874:CSPHI_RS09895
uniprot id: A0A1L7CZI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1437874:CSPHI RS11135
gene id: 1437874:CSPHI_RS11135
uniprot id: A0A1L7D067
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS00220
gene id: 1437874:CSPHI_RS00220
uniprot id: A0A1L7CVB7
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS05615
gene id: 1437874:CSPHI_RS05615
uniprot id: A0A1L7CXT3
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS02330
gene id: 1437874:CSPHI_RS02330
uniprot id: A0A1L7CW40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS01680
gene id: 1437874:CSPHI_RS01680
uniprot id: A0A1L7CW21
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1437874:CSPHI RS04645
gene id: 1437874:CSPHI_RS04645
uniprot id: A0A1L7CX83
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS06965
gene id: 1437874:CSPHI_RS06965
uniprot id: A0A1L7CYH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1437874:CSPHI RS05235
gene id: 1437874:CSPHI_RS05235
uniprot id: A0A1L7CXF9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1437874:CSPHI RS06955
gene id: 1437874:CSPHI_RS06955
uniprot id: A0A1L7CYM0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS02910
gene id: 1437874:CSPHI_RS02910
uniprot id: A0A1L7CWP4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1437874:CSPHI RS02700
gene id: 1437874:CSPHI_RS02700
uniprot id: A0A1L7CWH0
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1437874:CSPHI RS02815
gene id: 1437874:CSPHI_RS02815
uniprot id: A0A1L7CWJ6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1437874:CSPHI RS06430
gene id: 1437874:CSPHI_RS06430
uniprot id: A0A1L7CYA3
names: Similarity
messages: Belongs to the UPF0098 family.

1437874:CSPHI RS11190
gene id: 1437874:CSPHI_RS11190
uniprot id: A0A1L7D022
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1437874:CSPHI RS07055
gene id: 1437874:CSPHI_RS07055
uniprot id: A0A1L7CYP9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1437874:CSPHI RS07595
gene id: 1437874:CSPHI_RS07595
uniprot id: A0A1L7CYY4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1437874:CSPHI RS03155
gene id: 1437874:CSPHI_RS03155
uniprot id: A0A1L7CWP8
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1437874:CSPHI RS02165
gene id: 1437874:CSPHI_RS02165
uniprot id: A0A1L7CW95
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

1437874:CSPHI RS06075
gene id: 1437874:CSPHI_RS06075
uniprot id: A0A1L7CXW0
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1437874:CSPHI RS06545
gene id: 1437874:CSPHI_RS06545
uniprot id: A0A1L7CYC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1437874:CSPHI RS01730
gene id: 1437874:CSPHI_RS01730
uniprot id: A0A1L7CVZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1437874:CSPHI RS06520
gene id: 1437874:CSPHI_RS06520
uniprot id: A0A1L7CY87
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

1437874:CSPHI RS04300
gene id: 1437874:CSPHI_RS04300
uniprot id: A0A1L7CX97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1437874:CSPHI RS06540
gene id: 1437874:CSPHI_RS06540
uniprot id: A0A1L7CY80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1437874:CSPHI RS08910
gene id: 1437874:CSPHI_RS08910
uniprot id: A0A1L7CZ91
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS01545
gene id: 1437874:CSPHI_RS01545
uniprot id: A0A1L7CVX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1437874:CSPHI RS09330
gene id: 1437874:CSPHI_RS09330
uniprot id: A0A1L7CZJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1437874:CSPHI RS02290
gene id: 1437874:CSPHI_RS02290
uniprot id: A0A1L7CWA6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1437874:CSPHI RS10100
gene id: 1437874:CSPHI_RS10100
uniprot id: A0A1L7CZW4
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1437874:CSPHI RS10565
gene id: 1437874:CSPHI_RS10565
uniprot id: A0A1L7D0C4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1437874:CSPHI RS06185
gene id: 1437874:CSPHI_RS06185
uniprot id: A0A1L7CY30
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1437874:CSPHI RS07620
gene id: 1437874:CSPHI_RS07620
uniprot id: A0A1L7CYI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1437874:CSPHI RS08985
gene id: 1437874:CSPHI_RS08985
uniprot id: A0A1L7CZE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1437874:CSPHI RS09685
gene id: 1437874:CSPHI_RS09685
uniprot id: A0A1L7CZV1
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS08715
gene id: 1437874:CSPHI_RS08715
uniprot id: A0A1L7CZ01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

1437874:CSPHI RS03670
gene id: 1437874:CSPHI_RS03670
uniprot id: A0A1L7CX11
names: Similarity
messages: Belongs to the allantoicase family.

1437874:CSPHI RS09310
gene id: 1437874:CSPHI_RS09310
uniprot id: A0A1L7CZ96
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1437874:CSPHI RS06180
gene id: 1437874:CSPHI_RS06180
uniprot id: A0A1L7CXX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1437874:CSPHI RS02555
gene id: 1437874:CSPHI_RS02555
uniprot id: A0A1L7CW85
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1437874:CSPHI RS05925
gene id: 1437874:CSPHI_RS05925
uniprot id: A0A1L7CXT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1437874:CSPHI RS12365
gene id: 1437874:CSPHI_RS12365
uniprot id: A0A1L7CWY9
names: Similarity
messages: Belongs to the CsoR family.

1437874:CSPHI RS03460
gene id: 1437874:CSPHI_RS03460
uniprot id: A0A1L7CWN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1437874:CSPHI RS00645
gene id: 1437874:CSPHI_RS00645
uniprot id: A0A1L7CVK5
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

1437874:CSPHI RS11640
gene id: 1437874:CSPHI_RS11640
uniprot id: A0A1L7D081
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS07040
gene id: 1437874:CSPHI_RS07040
uniprot id: A0A1L7CYG0
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS11400
gene id: 1437874:CSPHI_RS11400
uniprot id: A0A1L7D055
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

1437874:CSPHI RS09560
gene id: 1437874:CSPHI_RS09560
uniprot id: A0A1L7CZJ5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS04060
gene id: 1437874:CSPHI_RS04060
uniprot id: A0A1L7CX05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

1437874:CSPHI RS07480
gene id: 1437874:CSPHI_RS07480
uniprot id: A0A1L7CYI3
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

1437874:CSPHI RS05450
gene id: 1437874:CSPHI_RS05450
uniprot id: A0A1L7CXJ5
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS05090
gene id: 1437874:CSPHI_RS05090
uniprot id: A0A1L7CXE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1437874:CSPHI RS07245
gene id: 1437874:CSPHI_RS07245
uniprot id: A0A1L7CYT3
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS08995
gene id: 1437874:CSPHI_RS08995
uniprot id: A0A1L7CZ54
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1437874:CSPHI RS05370
gene id: 1437874:CSPHI_RS05370
uniprot id: A0A1L7CXJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1437874:CSPHI RS04405
gene id: 1437874:CSPHI_RS04405
uniprot id: A0A1L7CX96
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS03810
gene id: 1437874:CSPHI_RS03810
uniprot id: A0A1L7CX00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1437874:CSPHI RS08840
gene id: 1437874:CSPHI_RS08840
uniprot id: A0A1L7CZ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1437874:CSPHI RS07870
gene id: 1437874:CSPHI_RS07870
uniprot id: A0A1L7CYU0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1437874:CSPHI RS03540
gene id: 1437874:CSPHI_RS03540
uniprot id: A0A1L7CWW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1437874:CSPHI RS07925
gene id: 1437874:CSPHI_RS07925
uniprot id: A0A1L7CZ44
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS06510
gene id: 1437874:CSPHI_RS06510
uniprot id: A0A1L7CY32
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

1437874:CSPHI RS02615
gene id: 1437874:CSPHI_RS02615
uniprot id: A0A1L7CWA0
names: Similarity
messages: Belongs to the thymidylate kinase family.

1437874:CSPHI RS01750
gene id: 1437874:CSPHI_RS01750
uniprot id: A0A1L7CW29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1437874:CSPHI RS02885
gene id: 1437874:CSPHI_RS02885
uniprot id: A0A1L7CWK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1437874:CSPHI RS06050
gene id: 1437874:CSPHI_RS06050
uniprot id: A0A1L7CY12
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS06690
gene id: 1437874:CSPHI_RS06690
uniprot id: A0A1L7CY62
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1437874:CSPHI RS00820
gene id: 1437874:CSPHI_RS00820
uniprot id: A0A1L7CVP5
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS09700
gene id: 1437874:CSPHI_RS09700
uniprot id: A0A1L7CZQ4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1437874:CSPHI RS10250
gene id: 1437874:CSPHI_RS10250
uniprot id: A0A1L7CZU9
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

1437874:CSPHI RS07110
gene id: 1437874:CSPHI_RS07110
uniprot id: A0A1L7CYC2
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1437874:CSPHI RS07160
gene id: 1437874:CSPHI_RS07160
uniprot id: A0A1L7CYD2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1437874:CSPHI RS01675
gene id: 1437874:CSPHI_RS01675
uniprot id: A0A1L7CVV1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1437874:CSPHI RS05430
gene id: 1437874:CSPHI_RS05430
uniprot id: A0A1L7CXL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1437874:CSPHI RS03830
gene id: 1437874:CSPHI_RS03830
uniprot id: A0A1L7CWU0
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1437874:CSPHI RS02115
gene id: 1437874:CSPHI_RS02115
uniprot id: A0A1L7CW46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

1437874:CSPHI RS00025
gene id: 1437874:CSPHI_RS00025
uniprot id: A0A1L7CVD0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1437874:CSPHI RS09545
gene id: 1437874:CSPHI_RS09545
uniprot id: A0A1L7CZJ3
names: Similarity
messages: Belongs to the AccD/PCCB family.

1437874:CSPHI RS08575
gene id: 1437874:CSPHI_RS08575
uniprot id: A0A1L7CZD1
names: Similarity
messages: Belongs to the UPF0225 family.

1437874:CSPHI RS09270
gene id: 1437874:CSPHI_RS09270
uniprot id: A0A1L7CZI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1437874:CSPHI RS10655
gene id: 1437874:CSPHI_RS10655
uniprot id: A0A1L7D041
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1437874:CSPHI RS05185
gene id: 1437874:CSPHI_RS05185
uniprot id: A0A1L7CXE8
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1437874:CSPHI RS10210
gene id: 1437874:CSPHI_RS10210
uniprot id: A0A1L7CZV5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1437874:CSPHI RS10850
gene id: 1437874:CSPHI_RS10850
uniprot id: A0A1L7D0G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1437874:CSPHI RS06960
gene id: 1437874:CSPHI_RS06960
uniprot id: A0A1L7CYE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1437874:CSPHI RS10490
gene id: 1437874:CSPHI_RS10490
uniprot id: A0A1L7CZZ6
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1437874:CSPHI RS01810
gene id: 1437874:CSPHI_RS01810
uniprot id: A0A1L7CW41
names: Similarity
messages: Belongs to the EccD/Snm4 family.

1437874:CSPHI RS11230
gene id: 1437874:CSPHI_RS11230
uniprot id: A0A1L7D0D6
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS05880
gene id: 1437874:CSPHI_RS05880
uniprot id: A0A1L7CY10
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1437874:CSPHI RS02270
gene id: 1437874:CSPHI_RS02270
uniprot id: A0A1L7CW75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1437874:CSPHI RS03690
gene id: 1437874:CSPHI_RS03690
uniprot id: A0A1L7CWU6
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1437874:CSPHI RS06010
gene id: 1437874:CSPHI_RS06010
uniprot id: A0A1L7CXY8
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1437874:CSPHI RS05215
gene id: 1437874:CSPHI_RS05215
uniprot id: A0A1L7CXF6
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1437874:CSPHI RS06600
gene id: 1437874:CSPHI_RS06600
uniprot id: A0A1L7CYA1
names: Similarity
messages: Belongs to the beta-eliminating lyase family.

1437874:CSPHI RS09230
gene id: 1437874:CSPHI_RS09230
uniprot id: A0A1L7CZ86
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS06020
gene id: 1437874:CSPHI_RS06020
uniprot id: A0A1L7CXV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1437874:CSPHI RS10220
gene id: 1437874:CSPHI_RS10220
uniprot id: A0A1L7CZU6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1437874:CSPHI RS01770
gene id: 1437874:CSPHI_RS01770
uniprot id: A0A1L7CW54
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1437874:CSPHI RS01685
gene id: 1437874:CSPHI_RS01685
uniprot id: A0A1L7CW15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1437874:CSPHI RS02440
gene id: 1437874:CSPHI_RS02440
uniprot id: A0A1L7CWA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1437874:CSPHI RS01755
gene id: 1437874:CSPHI_RS01755
uniprot id: A0A1L7CVX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1437874:CSPHI RS09480
gene id: 1437874:CSPHI_RS09480
uniprot id: A0A1L7CZI2
names: Similarity
messages: Belongs to the GcvT family.

1437874:CSPHI RS01155
gene id: 1437874:CSPHI_RS01155
uniprot id: A0A1L7CVQ1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1437874:CSPHI RS10065
gene id: 1437874:CSPHI_RS10065
uniprot id: A0A1L7CZK7
names: Similarity
messages: Belongs to the GARS family.

1437874:CSPHI RS06985
gene id: 1437874:CSPHI_RS06985
uniprot id: A0A1L7CYG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1437874:CSPHI RS06525
gene id: 1437874:CSPHI_RS06525
uniprot id: A0A1L7CY75
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

1437874:CSPHI RS09620
gene id: 1437874:CSPHI_RS09620
uniprot id: A0A1L7CZL1
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

1437874:CSPHI RS06015
gene id: 1437874:CSPHI_RS06015
uniprot id: A0A1L7CXV1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1437874:CSPHI RS05005
gene id: 1437874:CSPHI_RS05005
uniprot id: A0A1L7CXJ7
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Monomer.

1437874:CSPHI RS06135
gene id: 1437874:CSPHI_RS06135
uniprot id: A0A1L7CY11
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1437874:CSPHI RS02650
gene id: 1437874:CSPHI_RS02650
uniprot id: A0A1L7CWH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1437874:CSPHI RS01470
gene id: 1437874:CSPHI_RS01470
uniprot id: A0A1L7CW03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1437874:CSPHI RS07490
gene id: 1437874:CSPHI_RS07490
uniprot id: A0A1L7CYN3
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS08755
gene id: 1437874:CSPHI_RS08755
uniprot id: A0A1L7CZ04
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

1437874:CSPHI RS11495
gene id: 1437874:CSPHI_RS11495
uniprot id: A0A1L7D066
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS03265
gene id: 1437874:CSPHI_RS03265
uniprot id: A0A1L7CWR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1437874:CSPHI RS06220
gene id: 1437874:CSPHI_RS06220
uniprot id: A0A1L7CY27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1437874:CSPHI RS05575
gene id: 1437874:CSPHI_RS05575
uniprot id: A0A1L7CXQ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1437874:CSPHI RS07205
gene id: 1437874:CSPHI_RS07205
uniprot id: A0A1L7CYE3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1437874:CSPHI RS11120
gene id: 1437874:CSPHI_RS11120
uniprot id: A0A1L7D007
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

1437874:CSPHI RS06575
gene id: 1437874:CSPHI_RS06575
uniprot id: A0A1L7CY96
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1437874:CSPHI RS05705
gene id: 1437874:CSPHI_RS05705
uniprot id: A0A1L7CXQ9
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS00010
gene id: 1437874:CSPHI_RS00010
uniprot id: A0A1L7CVB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1437874:CSPHI RS08695
gene id: 1437874:CSPHI_RS08695
uniprot id: A0A1L7CYZ4
names: Similarity
messages: Belongs to the FBPase class 2 family.

1437874:CSPHI RS10680
gene id: 1437874:CSPHI_RS10680
uniprot id: A0A1L7CZV0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1437874:CSPHI RS00895
gene id: 1437874:CSPHI_RS00895
uniprot id: A0A1L7CVK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1437874:CSPHI RS09315
gene id: 1437874:CSPHI_RS09315
uniprot id: A0A1L7CZF5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1437874:CSPHI RS04715
gene id: 1437874:CSPHI_RS04715
uniprot id: A0A1L7CX70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1437874:CSPHI RS05405
gene id: 1437874:CSPHI_RS05405
uniprot id: A0A1L7CXR6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1437874:CSPHI RS01870
gene id: 1437874:CSPHI_RS01870
uniprot id: A0A1L7CW49
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1437874:CSPHI RS11420
gene id: 1437874:CSPHI_RS11420
uniprot id: A0A1L7D0N9
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

1437874:CSPHI RS06100
gene id: 1437874:CSPHI_RS06100
uniprot id: A0A1L7CY48
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1437874:CSPHI RS01430
gene id: 1437874:CSPHI_RS01430
uniprot id: A0A1L7CVX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1437874:CSPHI RS07805
gene id: 1437874:CSPHI_RS07805
uniprot id: A0A1L7CYT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

1437874:CSPHI RS07865
gene id: 1437874:CSPHI_RS07865
uniprot id: A0A1L7CYM6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1437874:CSPHI RS01415
gene id: 1437874:CSPHI_RS01415
uniprot id: A0A1L7CVQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1437874:CSPHI RS11000
gene id: 1437874:CSPHI_RS11000
uniprot id: A0A1L7D063
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1437874:CSPHI RS04225
gene id: 1437874:CSPHI_RS04225
uniprot id: A0A1L7CX54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1437874:CSPHI RS10580
gene id: 1437874:CSPHI_RS10580
uniprot id: A0A1L7CZZ3
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1437874:CSPHI RS05610
gene id: 1437874:CSPHI_RS05610
uniprot id: A0A1L7CXS6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS04515
gene id: 1437874:CSPHI_RS04515
uniprot id: A0A1L7CXA9
names: Similarity
messages: Belongs to the PrpD family.

1437874:CSPHI RS00775
gene id: 1437874:CSPHI_RS00775
uniprot id: A0A1L7CVJ6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1437874:CSPHI RS04430
gene id: 1437874:CSPHI_RS04430
uniprot id: A0A1L7CX41
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS00520
gene id: 1437874:CSPHI_RS00520
uniprot id: A0A1L7CVD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1437874:CSPHI RS00620
gene id: 1437874:CSPHI_RS00620
uniprot id: A0A1L7CVH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

1437874:CSPHI RS02770
gene id: 1437874:CSPHI_RS02770
uniprot id: A0A1L7CWD2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1437874:CSPHI RS09250
gene id: 1437874:CSPHI_RS09250
uniprot id: A0A1L7CZN1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1437874:CSPHI RS07975
gene id: 1437874:CSPHI_RS07975
uniprot id: A0A1L7CYW3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1437874:CSPHI RS09770
gene id: 1437874:CSPHI_RS09770
uniprot id: A0A1L7CZW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1437874:CSPHI RS08900
gene id: 1437874:CSPHI_RS08900
uniprot id: A0A1L7CZ70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1437874:CSPHI RS11050
gene id: 1437874:CSPHI_RS11050
uniprot id: A0A1L7CZZ9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1437874:CSPHI RS03550
gene id: 1437874:CSPHI_RS03550
uniprot id: A0A1L7CWS2
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1437874:CSPHI RS04275
gene id: 1437874:CSPHI_RS04275
uniprot id: A0A1L7CX67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1437874:CSPHI RS01460
gene id: 1437874:CSPHI_RS01460
uniprot id: A0A1L7CVY4
names: Similarity
messages: Belongs to the asp23 family.

1437874:CSPHI RS08410
gene id: 1437874:CSPHI_RS08410
uniprot id: A0A1L7CZ15
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1437874:CSPHI RS03240
gene id: 1437874:CSPHI_RS03240
uniprot id: A0A1L7CWM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1437874:CSPHI RS04330
gene id: 1437874:CSPHI_RS04330
uniprot id: A0A1L7CX76
names: Similarity
messages: Belongs to the UPF0045 family.

1437874:CSPHI RS01325
gene id: 1437874:CSPHI_RS01325
uniprot id: A0A1L7CVV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1437874:CSPHI RS06120
gene id: 1437874:CSPHI_RS06120
uniprot id: A0A1L7CXW5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS01625
gene id: 1437874:CSPHI_RS01625
uniprot id: A0A1L7CW05
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.

1437874:CSPHI RS05755
gene id: 1437874:CSPHI_RS05755
uniprot id: A0A1L7CXR2
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS00120
gene id: 1437874:CSPHI_RS00120
uniprot id: A0A1L7CVE0
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS06515
gene id: 1437874:CSPHI_RS06515
uniprot id: A0A1L7CY33
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

1437874:CSPHI RS10425
gene id: 1437874:CSPHI_RS10425
uniprot id: A0A1L7CZY6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1437874:CSPHI RS07135
gene id: 1437874:CSPHI_RS07135
uniprot id: A0A1L7CYI6
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1437874:CSPHI RS09305
gene id: 1437874:CSPHI_RS09305
uniprot id: A0A1L7CZC9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1437874:CSPHI RS08850
gene id: 1437874:CSPHI_RS08850
uniprot id: A0A1L7CZ88
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1437874:CSPHI RS10235
gene id: 1437874:CSPHI_RS10235
uniprot id: A0A1L7CZU3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1437874:CSPHI RS03710
gene id: 1437874:CSPHI_RS03710
uniprot id: A0A1L7CWZ5
names: Similarity
messages: Belongs to the peptidase M18 family.

1437874:CSPHI RS05360
gene id: 1437874:CSPHI_RS05360
uniprot id: A0A1L7CXL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1437874:CSPHI RS01740
gene id: 1437874:CSPHI_RS01740
uniprot id: A0A1L7CVW0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1437874:CSPHI RS06780
gene id: 1437874:CSPHI_RS06780
uniprot id: A0A1L7CYB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1437874:CSPHI RS02090
gene id: 1437874:CSPHI_RS02090
uniprot id: A0A1L7CW20
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

1437874:CSPHI RS07895
gene id: 1437874:CSPHI_RS07895
uniprot id: A0A1L7CYP3
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS00605
gene id: 1437874:CSPHI_RS00605
uniprot id: A0A1L7CVL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

1437874:CSPHI RS09365
gene id: 1437874:CSPHI_RS09365
uniprot id: A0A1L7CZA8
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1437874:CSPHI RS04670
gene id: 1437874:CSPHI_RS04670
uniprot id: A0A1L7CXC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1437874:CSPHI RS08990
gene id: 1437874:CSPHI_RS08990
uniprot id: A0A1L7CZA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1437874:CSPHI RS06465
gene id: 1437874:CSPHI_RS06465
uniprot id: A0A1L7CY23
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1437874:CSPHI RS11470
gene id: 1437874:CSPHI_RS11470
uniprot id: A0A1L7D0D2
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1437874:CSPHI RS05045
gene id: 1437874:CSPHI_RS05045
uniprot id: A0A1L7CXJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1437874:CSPHI RS10880
gene id: 1437874:CSPHI_RS10880
uniprot id: A0A1L7CZY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1437874:CSPHI RS01050
gene id: 1437874:CSPHI_RS01050
uniprot id: A0A1L7CVS7
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1437874:CSPHI RS08895
gene id: 1437874:CSPHI_RS08895
uniprot id: A0A1L7CZ94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1437874:CSPHI RS07920
gene id: 1437874:CSPHI_RS07920
uniprot id: A0A1L7CYU8
names: Similarity
messages: Belongs to the glutamine synthetase family.

1437874:CSPHI RS09705
gene id: 1437874:CSPHI_RS09705
uniprot id: A0A1L7CZL6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1437874:CSPHI RS04320
gene id: 1437874:CSPHI_RS04320
uniprot id: A0A1L7CX23
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS05560
gene id: 1437874:CSPHI_RS05560
uniprot id: A0A1L7CXR4
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1437874:CSPHI RS07845
gene id: 1437874:CSPHI_RS07845
uniprot id: A0A1L7CYN1
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1437874:CSPHI RS09605
gene id: 1437874:CSPHI_RS09605
uniprot id: A0A1L7CZE8
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1437874:CSPHI RS09165
gene id: 1437874:CSPHI_RS09165
uniprot id: A0A1L7CZL9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

1437874:CSPHI RS05050
gene id: 1437874:CSPHI_RS05050
uniprot id: A0A1L7CXC8
names: Similarity
messages: Belongs to the P(II) protein family.

1437874:CSPHI RS06950
gene id: 1437874:CSPHI_RS06950
uniprot id: A0A1L7CYE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1437874:CSPHI RS06095
gene id: 1437874:CSPHI_RS06095
uniprot id: A0A1L7CXZ2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS02715
gene id: 1437874:CSPHI_RS02715
uniprot id: A0A1L7CWI5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1437874:CSPHI RS00260
gene id: 1437874:CSPHI_RS00260
uniprot id: A0A1L7CVE8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1437874:CSPHI RS03530
gene id: 1437874:CSPHI_RS03530
uniprot id: A0A1L7CWP7
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1437874:CSPHI RS07675
gene id: 1437874:CSPHI_RS07675
uniprot id: A0A1L7CYK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1437874:CSPHI RS07740
gene id: 1437874:CSPHI_RS07740
uniprot id: A0A1L7CYK8
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

1437874:CSPHI RS00445
gene id: 1437874:CSPHI_RS00445
uniprot id: A0A1L7CVB2
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

1437874:CSPHI RS06130
gene id: 1437874:CSPHI_RS06130
uniprot id: A0A1L7CY22
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS06055
gene id: 1437874:CSPHI_RS06055
uniprot id: A0A1L7CY24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1437874:CSPHI RS02585
gene id: 1437874:CSPHI_RS02585
uniprot id: A0A1L7CWG4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1437874:CSPHI RS01560
gene id: 1437874:CSPHI_RS01560
uniprot id: A0A1L7CVT2
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS01485
gene id: 1437874:CSPHI_RS01485
uniprot id: A0A1L7CVR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1437874:CSPHI RS00540
gene id: 1437874:CSPHI_RS00540
uniprot id: A0A1L7CVK1
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

1437874:CSPHI RS01510
gene id: 1437874:CSPHI_RS01510
uniprot id: A0A1L7CVZ3
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1437874:CSPHI RS04455
gene id: 1437874:CSPHI_RS04455
uniprot id: A0A1L7CX37
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1437874:CSPHI RS09550
gene id: 1437874:CSPHI_RS09550
uniprot id: A0A1L7CZG9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1437874:CSPHI RS05395
gene id: 1437874:CSPHI_RS05395
uniprot id: A0A1L7CXN8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1437874:CSPHI RS04685
gene id: 1437874:CSPHI_RS04685
uniprot id: A0A1L7CXC4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1437874:CSPHI RS07635
gene id: 1437874:CSPHI_RS07635
uniprot id: A0A1L7CYP1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS05245
gene id: 1437874:CSPHI_RS05245
uniprot id: A0A1L7CXL9
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1437874:CSPHI RS02415
gene id: 1437874:CSPHI_RS02415
uniprot id: A0A1L7CWD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1437874:CSPHI RS00315
gene id: 1437874:CSPHI_RS00315
uniprot id: A0A1L7CV92
names: Similarity
names: Subunit
messages: Belongs to the multicopper oxidase family.
messages: Homotrimer.

1437874:CSPHI RS04540
gene id: 1437874:CSPHI_RS04540
uniprot id: A0A1L7CXB5
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1437874:CSPHI RS03535
gene id: 1437874:CSPHI_RS03535
uniprot id: A0A1L7CWV4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1437874:CSPHI RS08745
gene id: 1437874:CSPHI_RS08745
uniprot id: A0A1L7CZ66
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1437874:CSPHI RS05040
gene id: 1437874:CSPHI_RS05040
uniprot id: A0A1L7CXI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1437874:CSPHI RS01890
gene id: 1437874:CSPHI_RS01890
uniprot id: A0A1L7CW55
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1437874:CSPHI RS03820
gene id: 1437874:CSPHI_RS03820
uniprot id: A0A1L7CWW4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.

1437874:CSPHI RS03050
gene id: 1437874:CSPHI_RS03050
uniprot id: A0A1L7CWH2
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS03975
gene id: 1437874:CSPHI_RS03975
uniprot id: A0A1L7CWY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1437874:CSPHI RS05320
gene id: 1437874:CSPHI_RS05320
uniprot id: A0A1L7CXH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1437874:CSPHI RS08700
gene id: 1437874:CSPHI_RS08700
uniprot id: A0A1L7CZ62
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1437874:CSPHI RS05770
gene id: 1437874:CSPHI_RS05770
uniprot id: A0A1L7CXW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1437874:CSPHI RS11510
gene id: 1437874:CSPHI_RS11510
uniprot id: A0A1L7D090
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1437874:CSPHI RS06245
gene id: 1437874:CSPHI_RS06245
uniprot id: A0A1L7CXX6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1437874:CSPHI RS00650
gene id: 1437874:CSPHI_RS00650
uniprot id: A0A1L7CVF2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS08760
gene id: 1437874:CSPHI_RS08760
uniprot id: A0A1L7CZ73
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS01650
gene id: 1437874:CSPHI_RS01650
uniprot id: A0A1L7CW19
names: Similarity
messages: Belongs to the isochorismate synthase family.

1437874:CSPHI RS03440
gene id: 1437874:CSPHI_RS03440
uniprot id: A0A1L7CWN4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1437874:CSPHI RS05545
gene id: 1437874:CSPHI_RS05545
uniprot id: A0A1L7CXT8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1437874:CSPHI RS07850
gene id: 1437874:CSPHI_RS07850
uniprot id: A0A1L7CYM5
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1437874:CSPHI RS01340
gene id: 1437874:CSPHI_RS01340
uniprot id: A0A1L7CVW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1437874:CSPHI RS01160
gene id: 1437874:CSPHI_RS01160
uniprot id: A0A1L7CVR5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1437874:CSPHI RS10255
gene id: 1437874:CSPHI_RS10255
uniprot id: A0A1L7CZS9
names: Similarity
messages: Belongs to the Nth/MutY family.

1437874:CSPHI RS09395
gene id: 1437874:CSPHI_RS09395
uniprot id: A0A1L7CZG5
names: Similarity
messages: Belongs to the AccD/PCCB family.

1437874:CSPHI RS06890
gene id: 1437874:CSPHI_RS06890
uniprot id: A0A1L7CYG1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS03765
gene id: 1437874:CSPHI_RS03765
uniprot id: A0A1L7CWT0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1437874:CSPHI RS01495
gene id: 1437874:CSPHI_RS01495
uniprot id: A0A1L7CVZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1437874:CSPHI RS04420
gene id: 1437874:CSPHI_RS04420
uniprot id: A0A1L7CX65
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1437874:CSPHI RS05935
gene id: 1437874:CSPHI_RS05935
uniprot id: A0A1L7CY19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1437874:CSPHI RS05535
gene id: 1437874:CSPHI_RS05535
uniprot id: A0A1L7CXM4
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS07065
gene id: 1437874:CSPHI_RS07065
uniprot id: A0A1L7CYK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1437874:CSPHI RS01775
gene id: 1437874:CSPHI_RS01775
uniprot id: A0A1L7CVZ7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1437874:CSPHI RS05390
gene id: 1437874:CSPHI_RS05390
uniprot id: A0A1L7CXI7
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS06205
gene id: 1437874:CSPHI_RS06205
uniprot id: A0A1L7CY65
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1437874:CSPHI RS00855
gene id: 1437874:CSPHI_RS00855
uniprot id: A0A1L7D0A9
names: Similarity
messages: Belongs to the GSP E family.

1437874:CSPHI RS09670
gene id: 1437874:CSPHI_RS09670
uniprot id: A0A1L7CZF9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1437874:CSPHI RS01490
gene id: 1437874:CSPHI_RS01490
uniprot id: A0A1L7CVS4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1437874:CSPHI RS09035
gene id: 1437874:CSPHI_RS09035
uniprot id: A0A1L7CZK1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS06040
gene id: 1437874:CSPHI_RS06040
uniprot id: A0A1L7CXY2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1437874:CSPHI RS07705
gene id: 1437874:CSPHI_RS07705
uniprot id: A0A1L7CYJ9
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1437874:CSPHI RS04350
gene id: 1437874:CSPHI_RS04350
uniprot id: A0A1L7CXA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

1437874:CSPHI RS08055
gene id: 1437874:CSPHI_RS08055
uniprot id: A0A1L7CYX3
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1437874:CSPHI RS00410
gene id: 1437874:CSPHI_RS00410
uniprot id: A0A1L7CVH9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1437874:CSPHI RS00610
gene id: 1437874:CSPHI_RS00610
uniprot id: A0A1L7CVG0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

1437874:CSPHI RS01930
gene id: 1437874:CSPHI_RS01930
uniprot id: A0A1L7CW60
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

1437874:CSPHI RS06990
gene id: 1437874:CSPHI_RS06990
uniprot id: A0A1L7CYF2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1437874:CSPHI RS08490
gene id: 1437874:CSPHI_RS08490
uniprot id: A0A1L7CYW4
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1437874:CSPHI RS06995
gene id: 1437874:CSPHI_RS06995
uniprot id: A0A1L7CYA2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1437874:CSPHI RS00585
gene id: 1437874:CSPHI_RS00585
uniprot id: A0A1L7CVJ9
names: Similarity
messages: Belongs to the DnaX/STICHEL family.

1437874:CSPHI RS03555
gene id: 1437874:CSPHI_RS03555
uniprot id: A0A1L7CWT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1437874:CSPHI RS11660
gene id: 1437874:CSPHI_RS11660
uniprot id: A0A1L7D0A8
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1437874:CSPHI RS01505
gene id: 1437874:CSPHI_RS01505
uniprot id: A0A1L7CVT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1437874:CSPHI RS10505
gene id: 1437874:CSPHI_RS10505
uniprot id: A0A1L7CZY9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS07230
gene id: 1437874:CSPHI_RS07230
uniprot id: A0A1L7CYE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

1437874:CSPHI RS03065
gene id: 1437874:CSPHI_RS03065
uniprot id: A0A1L7CWP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1437874:CSPHI RS06590
gene id: 1437874:CSPHI_RS06590
uniprot id: A0A1L7CY89
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1437874:CSPHI RS05675
gene id: 1437874:CSPHI_RS05675
uniprot id: A0A1L7CXX9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1437874:CSPHI RS03090
gene id: 1437874:CSPHI_RS03090
uniprot id: A0A1L7CWP5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1437874:CSPHI RS04285
gene id: 1437874:CSPHI_RS04285
uniprot id: A0A1L7CX08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1437874:CSPHI RS06935
gene id: 1437874:CSPHI_RS06935
uniprot id: A0A1L7CYE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1437874:CSPHI RS09655
gene id: 1437874:CSPHI_RS09655
uniprot id: A0A1L7CZE6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS01090
gene id: 1437874:CSPHI_RS01090
uniprot id: A0A1L7CVQ2
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1437874:CSPHI RS02500
gene id: 1437874:CSPHI_RS02500
uniprot id: A0A1L7CWB9
names: Similarity
messages: Belongs to the AccD/PCCB family.

1437874:CSPHI RS01765
gene id: 1437874:CSPHI_RS01765
uniprot id: A0A1L7CW35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1437874:CSPHI RS03785
gene id: 1437874:CSPHI_RS03785
uniprot id: A0A1L7CX04
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-70 and Arg-73) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1437874:CSPHI RS10955
gene id: 1437874:CSPHI_RS10955
uniprot id: A0A1L7D071
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS11635
gene id: 1437874:CSPHI_RS11635
uniprot id: A0A1L7D0D1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1437874:CSPHI RS01860
gene id: 1437874:CSPHI_RS01860
uniprot id: A0A1L7CVX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1437874:CSPHI RS03635
gene id: 1437874:CSPHI_RS03635
uniprot id: A0A1L7CWW9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1437874:CSPHI RS01760
gene id: 1437874:CSPHI_RS01760
uniprot id: A0A1L7CW33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1437874:CSPHI RS05290
gene id: 1437874:CSPHI_RS05290
uniprot id: A0A1L7CXL7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1437874:CSPHI RS07825
gene id: 1437874:CSPHI_RS07825
uniprot id: A0A1L7CZ27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1437874:CSPHI RS06840
gene id: 1437874:CSPHI_RS06840
uniprot id: A0A1L7CY82
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

1437874:CSPHI RS04270
gene id: 1437874:CSPHI_RS04270
uniprot id: A0A1L7CX12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1437874:CSPHI RS07830
gene id: 1437874:CSPHI_RS07830
uniprot id: A0A1L7CYT9
names: Similarity
messages: Belongs to the asparagine synthetase family.

1437874:CSPHI RS04475
gene id: 1437874:CSPHI_RS04475
uniprot id: A0A1L7CXA5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS02145
gene id: 1437874:CSPHI_RS02145
uniprot id: A0A1L7CW89
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1437874:CSPHI RS06110
gene id: 1437874:CSPHI_RS06110
uniprot id: A0A1L7CY35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1437874:CSPHI RS00345
gene id: 1437874:CSPHI_RS00345
uniprot id: A0A1L7CVG9
names: Similarity
messages: Belongs to the peptidase M13 family.

1437874:CSPHI RS06400
gene id: 1437874:CSPHI_RS06400
uniprot id: A0A1L7CY13
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1437874:CSPHI RS05200
gene id: 1437874:CSPHI_RS05200
uniprot id: A0A1L7CXM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1437874:CSPHI RS08705
gene id: 1437874:CSPHI_RS08705
uniprot id: A0A1L7CZ43
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1437874:CSPHI RS10605
gene id: 1437874:CSPHI_RS10605
uniprot id: A0A1L7CZU7
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1437874:CSPHI RS06410
gene id: 1437874:CSPHI_RS06410
uniprot id: A0A1L7CY61
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1437874:CSPHI RS10560
gene id: 1437874:CSPHI_RS10560
uniprot id: A0A1L7D006
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1437874:CSPHI RS11310
gene id: 1437874:CSPHI_RS11310
uniprot id: A0A1L7D0E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1437874:CSPHI RS02445
gene id: 1437874:CSPHI_RS02445
uniprot id: A0A1L7CW64
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1437874:CSPHI RS05740
gene id: 1437874:CSPHI_RS05740
uniprot id: A0A1L7CXW4
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1437874:CSPHI RS08020
gene id: 1437874:CSPHI_RS08020
uniprot id: A0A1L7CZ06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1437874:CSPHI RS06945
gene id: 1437874:CSPHI_RS06945
uniprot id: A0A1L7CY85
names: Similarity
messages: Belongs to the UPF0434 family.

1437874:CSPHI RS06260
gene id: 1437874:CSPHI_RS06260
uniprot id: A0A1L7CY47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

1437874:CSPHI RS07800
gene id: 1437874:CSPHI_RS07800
uniprot id: A0A1L7CYL5
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

1437874:CSPHI RS02850
gene id: 1437874:CSPHI_RS02850
uniprot id: A0A1L7CWK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1437874:CSPHI RS11375
gene id: 1437874:CSPHI_RS11375
uniprot id: A0A1L7D093
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

1437874:CSPHI RS10440
gene id: 1437874:CSPHI_RS10440
uniprot id: A0A1L7D010
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1437874:CSPHI RS02510
gene id: 1437874:CSPHI_RS02510
uniprot id: A0A1L7CW80
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1437874:CSPHI RS11465
gene id: 1437874:CSPHI_RS11465
uniprot id: A0A1L7D064
names: Similarity
messages: Belongs to the fructosamine kinase family.

1437874:CSPHI RS09430
gene id: 1437874:CSPHI_RS09430
uniprot id: A0A1L7CZB7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS06485
gene id: 1437874:CSPHI_RS06485
uniprot id: A0A1L7CY66
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1437874:CSPHI RS09320
gene id: 1437874:CSPHI_RS09320
uniprot id: A0A1L7CZP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1437874:CSPHI RS02485
gene id: 1437874:CSPHI_RS02485
uniprot id: A0A1L7CWG3
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1437874:CSPHI RS04130
gene id: 1437874:CSPHI_RS04130
uniprot id: A0A1L7CX43
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1437874:CSPHI RS08780
gene id: 1437874:CSPHI_RS08780
uniprot id: A0A1L7CZG0
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1437874:CSPHI RS00480
gene id: 1437874:CSPHI_RS00480
uniprot id: A0A1L7CVC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

1437874:CSPHI RS04210
gene id: 1437874:CSPHI_RS04210
uniprot id: A0A1L7CWY6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1437874:CSPHI RS01835
gene id: 1437874:CSPHI_RS01835
uniprot id: A0A1L7CW43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1437874:CSPHI RS03705
gene id: 1437874:CSPHI_RS03705
uniprot id: A0A1L7CWS4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437874:CSPHI RS07900
gene id: 1437874:CSPHI_RS07900
uniprot id: A0A1L7CYN4
names: Similarity
messages: Belongs to the glutamine synthetase family.

1437874:CSPHI RS09220
gene id: 1437874:CSPHI_RS09220
uniprot id: A0A1L7CZE3
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS08650
gene id: 1437874:CSPHI_RS08650
uniprot id: A0A1L7CZE0
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1437874:CSPHI RS07050
gene id: 1437874:CSPHI_RS07050
uniprot id: A0A1L7CYG7
names: Similarity
messages: Belongs to the universal stress protein A family.

1437874:CSPHI RS01205
gene id: 1437874:CSPHI_RS01205
uniprot id: A0A1L7CVV0
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS05660
gene id: 1437874:CSPHI_RS05660
uniprot id: A0A1L7CXU3
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1437874:CSPHI RS07580
gene id: 1437874:CSPHI_RS07580
uniprot id: A0A1L7CYI0
names: Similarity
messages: Belongs to the asparaginase 1 family.

1437874:CSPHI RS04345
gene id: 1437874:CSPHI_RS04345
uniprot id: A0A1L7CX80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1437874:CSPHI RS06435
gene id: 1437874:CSPHI_RS06435
uniprot id: A0A1L7CY74
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1437874:CSPHI RS02335
gene id: 1437874:CSPHI_RS02335
uniprot id: A0A1L7CW45
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS06150
gene id: 1437874:CSPHI_RS06150
uniprot id: A0A1L7CY59
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1437874:CSPHI RS05315
gene id: 1437874:CSPHI_RS05315
uniprot id: A0A1L7CXJ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1437874:CSPHI RS07505
gene id: 1437874:CSPHI_RS07505
uniprot id: A0A1L7CYN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

1437874:CSPHI RS06000
gene id: 1437874:CSPHI_RS06000
uniprot id: A0A1L7CY15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1437874:CSPHI RS00555
gene id: 1437874:CSPHI_RS00555
uniprot id: A0A1L7CVG1
names: Similarity
messages: Belongs to the CsoR family.

1437874:CSPHI RS01120
gene id: 1437874:CSPHI_RS01120
uniprot id: A0A1L7CVM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1437874:CSPHI RS05970
gene id: 1437874:CSPHI_RS05970
uniprot id: A0A1L7CXX7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1437874:CSPHI RS02085
gene id: 1437874:CSPHI_RS02085
uniprot id: A0A1L7CW71
names: Subcellular Location Annotation
messages: Membrane

1437874:CSPHI RS05620
gene id: 1437874:CSPHI_RS05620
uniprot id: A0A1L7CXU9
names: Similarity
messages: Belongs to the neutral ceramidase family.

1437874:CSPHI RS07180
gene id: 1437874:CSPHI_RS07180
uniprot id: A0A1L7CYM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1437874:CSPHI RS02380
gene id: 1437874:CSPHI_RS02380
uniprot id: A0A1L7CW94
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1437874:CSPHI RS02805
gene id: 1437874:CSPHI_RS02805
uniprot id: A0A1L7CWC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1437874:CSPHI RS11730
gene id: 1437874:CSPHI_RS11730
uniprot id: A0A1L7D0A1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1437874:CSPHI RS00195
gene id: 1437874:CSPHI_RS00195
uniprot id: A0A1L7CVF1
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1437874:CSPHI RS07115
gene id: 1437874:CSPHI_RS07115
uniprot id: A0A1L7CYH6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1437874:CSPHI RS05460
gene id: 1437874:CSPHI_RS05460
uniprot id: A0A1L7CXQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1437874:CSPHI RS03620
gene id: 1437874:CSPHI_RS03620
uniprot id: A0A1L7CWQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437874:CSPHI RS10970
gene id: 1437874:CSPHI_RS10970
uniprot id: A0A1L7CZZ1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1437874:CSPHI RS11515
gene id: 1437874:CSPHI_RS11515
uniprot id: A0A1L7D074
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.