1423732:LBCZ RS04470
gene id: 1423732:LBCZ_RS04470
uniprot id: S6BQV0
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1423732:LBCZ RS01465
gene id: 1423732:LBCZ_RS01465
uniprot id: S6C8Q0
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

1423732:LBCZ RS11910
gene id: 1423732:LBCZ_RS11910
uniprot id: S6CK16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1423732:LBCZ RS06080
gene id: 1423732:LBCZ_RS06080
uniprot id: S6CJD5
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1423732:LBCZ RS11715
gene id: 1423732:LBCZ_RS11715
uniprot id: S6BUV6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1423732:LBCZ RS07620
gene id: 1423732:LBCZ_RS07620
uniprot id: S6CAI2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1423732:LBCZ RS13415
gene id: 1423732:LBCZ_RS13415
uniprot id: S6CK74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS04530
gene id: 1423732:LBCZ_RS04530
uniprot id: S6BX61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1423732:LBCZ RS05160
gene id: 1423732:LBCZ_RS05160
uniprot id: S6C6X8
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS06390
gene id: 1423732:LBCZ_RS06390
uniprot id: S6C7R0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1423732:LBCZ RS06890
gene id: 1423732:LBCZ_RS06890
uniprot id: S6BYJ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.

1423732:LBCZ RS07305
gene id: 1423732:LBCZ_RS07305
uniprot id: S6BS98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1423732:LBCZ RS00945
gene id: 1423732:LBCZ_RS00945
uniprot id: S6BP13
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1423732:LBCZ RS09295
gene id: 1423732:LBCZ_RS09295
uniprot id: S6C0I1
names: Similarity
messages: Belongs to the Fur family.

1423732:LBCZ RS08170
gene id: 1423732:LBCZ_RS08170
uniprot id: S6BST7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1423732:LBCZ RS08070
gene id: 1423732:LBCZ_RS08070
uniprot id: S6CAU1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1423732:LBCZ RS09330
gene id: 1423732:LBCZ_RS09330
uniprot id: S6CB38
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS12085
gene id: 1423732:LBCZ_RS12085
uniprot id: S6CC50
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1423732:LBCZ RS02910
gene id: 1423732:LBCZ_RS02910
uniprot id: S6C636
names: Similarity
messages: Belongs to the thioredoxin family.

1423732:LBCZ RS04490
gene id: 1423732:LBCZ_RS04490
uniprot id: S6C9T4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1423732:LBCZ RS08405
gene id: 1423732:LBCZ_RS08405
uniprot id: S6CAW4
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1423732:LBCZ RS01085
gene id: 1423732:LBCZ_RS01085
uniprot id: S6BP29
names: Similarity
messages: Belongs to the peptidase C40 family.

1423732:LBCZ RS10680
gene id: 1423732:LBCZ_RS10680
uniprot id: S6CA03
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1423732:LBCZ RS00715
gene id: 1423732:LBCZ_RS00715
uniprot id: S6C8G0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

1423732:LBCZ RS11810
gene id: 1423732:LBCZ_RS11810
uniprot id: S6CAA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1423732:LBCZ RS01190
gene id: 1423732:LBCZ_RS01190
uniprot id: S6C5B5
names: Subcellular Location Annotation
messages: Cytoplasm

1423732:LBCZ RS14070
gene id: 1423732:LBCZ_RS14070
uniprot id: S6CB27
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1423732:LBCZ RS00315
gene id: 1423732:LBCZ_RS00315
uniprot id: S6CIR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1423732:LBCZ RS02565
gene id: 1423732:LBCZ_RS02565
uniprot id: S6BW79
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1423732:LBCZ RS11695
gene id: 1423732:LBCZ_RS11695
uniprot id: S6CA88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

1423732:LBCZ RS12245
gene id: 1423732:LBCZ_RS12245
uniprot id: S6CK27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1423732:LBCZ RS07735
gene id: 1423732:LBCZ_RS07735
uniprot id: S6CJK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1423732:LBCZ RS13285
gene id: 1423732:LBCZ_RS13285
uniprot id: S6BVX5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS00870
gene id: 1423732:LBCZ_RS00870
uniprot id: S6BP00
names: Function
names: Similarity
messages: Belongs to the IolE/MocC family.
messages: Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).

1423732:LBCZ RS14095
gene id: 1423732:LBCZ_RS14095
uniprot id: S6CB29
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1423732:LBCZ RS09245
gene id: 1423732:LBCZ_RS09245
uniprot id: S6C0H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1423732:LBCZ RS06745
gene id: 1423732:LBCZ_RS06745
uniprot id: S6CA85
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS02155
gene id: 1423732:LBCZ_RS02155
uniprot id: S6BPP4
names: Subcellular Location Annotation
messages: Cytoplasm

1423732:LBCZ RS02955
gene id: 1423732:LBCZ_RS02955
uniprot id: S6BQ79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1423732:LBCZ RS08650
gene id: 1423732:LBCZ_RS08650
uniprot id: S6CJN7
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1423732:LBCZ RS02725
gene id: 1423732:LBCZ_RS02725
uniprot id: S6BWH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cell envelope
messages: Releases the N-terminal proline from various substrates.

1423732:LBCZ RS06985
gene id: 1423732:LBCZ_RS06985
uniprot id: S6CJH2
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
messages: Homohexamer.

1423732:LBCZ RS01675
gene id: 1423732:LBCZ_RS01675
uniprot id: S6C5K8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-serine, forming acetyl-L-serine.

1423732:LBCZ RS01030
gene id: 1423732:LBCZ_RS01030
uniprot id: S6C8J4
names: Similarity
messages: Belongs to the thioredoxin family.

1423732:LBCZ RS00835
gene id: 1423732:LBCZ_RS00835
uniprot id: S6CIT7
names: Function
names: Similarity
messages: Belongs to the isomerase IolB family.
messages: Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D-gluconate).

1423732:LBCZ RS02810
gene id: 1423732:LBCZ_RS02810
uniprot id: S6BQ57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1423732:LBCZ RS02920
gene id: 1423732:LBCZ_RS02920
uniprot id: S6BWK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily.
messages: Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
messages: Cytoplasm

1423732:LBCZ RS02870
gene id: 1423732:LBCZ_RS02870
uniprot id: S6CJ17
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS10205
gene id: 1423732:LBCZ_RS10205
uniprot id: S6CJU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1423732:LBCZ RS14145
gene id: 1423732:LBCZ_RS14145
uniprot id: S6CB35
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1423732:LBCZ RS10065
gene id: 1423732:LBCZ_RS10065
uniprot id: S6CBD6
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS10255
gene id: 1423732:LBCZ_RS10255
uniprot id: S6C0X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1423732:LBCZ RS11200
gene id: 1423732:LBCZ_RS11200
uniprot id: S6CJY8
names: Subcellular Location Annotation
messages: Cell membrane

1423732:LBCZ RS06900
gene id: 1423732:LBCZ_RS06900
uniprot id: S6BS42
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1423732:LBCZ RS00930
gene id: 1423732:LBCZ_RS00930
uniprot id: S6CIU1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1423732:LBCZ RS09920
gene id: 1423732:LBCZ_RS09920
uniprot id: S6C9G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1423732:LBCZ RS09825
gene id: 1423732:LBCZ_RS09825
uniprot id: S6C0R1
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1423732:LBCZ RS03155
gene id: 1423732:LBCZ_RS03155
uniprot id: S6BWP0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1423732:LBCZ RS10490
gene id: 1423732:LBCZ_RS10490
uniprot id: S6BU98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1423732:LBCZ RS09270
gene id: 1423732:LBCZ_RS09270
uniprot id: S6C0H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS01180
gene id: 1423732:LBCZ_RS01180
uniprot id: S6C8L0
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1423732:LBCZ RS01630
gene id: 1423732:LBCZ_RS01630
uniprot id: S6C5K1
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS07400
gene id: 1423732:LBCZ_RS07400
uniprot id: S6BYT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1423732:LBCZ RS09530
gene id: 1423732:LBCZ_RS09530
uniprot id: S6BTH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS06355
gene id: 1423732:LBCZ_RS06355
uniprot id: S6CA52
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

1423732:LBCZ RS01070
gene id: 1423732:LBCZ_RS01070
uniprot id: S6CIU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1423732:LBCZ RS07265
gene id: 1423732:LBCZ_RS07265
uniprot id: S6CJI2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS06580
gene id: 1423732:LBCZ_RS06580
uniprot id: S6CA69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family. ParE type 2 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1423732:LBCZ RS08820
gene id: 1423732:LBCZ_RS08820
uniprot id: S6CJP3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS02860
gene id: 1423732:LBCZ_RS02860
uniprot id: S6BQ62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. CshB subfamily.
messages: Cytoplasm
messages: Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures.

1423732:LBCZ RS10445
gene id: 1423732:LBCZ_RS10445
uniprot id: S6C9Q0
names: Similarity
messages: Belongs to the asparaginase 1 family.

1423732:LBCZ RS01175
gene id: 1423732:LBCZ_RS01175
uniprot id: S6BVJ3
names: Similarity
messages: Belongs to the SIS family. AgaS subfamily.

1423732:LBCZ RS07425
gene id: 1423732:LBCZ_RS07425
uniprot id: S6CAF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1423732:LBCZ RS08490
gene id: 1423732:LBCZ_RS08490
uniprot id: S6C943
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1423732:LBCZ RS02310
gene id: 1423732:LBCZ_RS02310
uniprot id: S6C5S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

1423732:LBCZ RS08015
gene id: 1423732:LBCZ_RS08015
uniprot id: S6BZV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1423732:LBCZ RS12445
gene id: 1423732:LBCZ_RS12445
uniprot id: S6CAI5
names: Similarity
messages: Belongs to the UPF0177 family.

1423732:LBCZ RS06435
gene id: 1423732:LBCZ_RS06435
uniprot id: S6BRW9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1423732:LBCZ RS08980
gene id: 1423732:LBCZ_RS08980
uniprot id: S6C0B3
names: Subcellular Location Annotation
messages: Cell membrane

1423732:LBCZ RS12235
gene id: 1423732:LBCZ_RS12235
uniprot id: S6BV49
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1423732:LBCZ RS01165
gene id: 1423732:LBCZ_RS01165
uniprot id: S6C5B0
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1423732:LBCZ RS04305
gene id: 1423732:LBCZ_RS04305
uniprot id: S6BQS0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1423732:LBCZ RS06790
gene id: 1423732:LBCZ_RS06790
uniprot id: S6BYH9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1423732:LBCZ RS04235
gene id: 1423732:LBCZ_RS04235
uniprot id: S6BQQ5
names: Similarity
messages: Belongs to the IMPACT family.

1423732:LBCZ RS12185
gene id: 1423732:LBCZ_RS12185
uniprot id: S6BV39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1423732:LBCZ RS01290
gene id: 1423732:LBCZ_RS01290
uniprot id: S6BP76
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1423732:LBCZ RS02640
gene id: 1423732:LBCZ_RS02640
uniprot id: S6BQ07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1423732:LBCZ RS08840
gene id: 1423732:LBCZ_RS08840
uniprot id: S6C969
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

1423732:LBCZ RS11845
gene id: 1423732:LBCZ_RS11845
uniprot id: S6C1W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Membrane

1423732:LBCZ RS13215
gene id: 1423732:LBCZ_RS13215
uniprot id: S6BVW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS06885
gene id: 1423732:LBCZ_RS06885
uniprot id: S6CJG8
names: Similarity
messages: Belongs to the UPF0398 family.

1423732:LBCZ RS10540
gene id: 1423732:LBCZ_RS10540
uniprot id: S6BUA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1423732:LBCZ RS06980
gene id: 1423732:LBCZ_RS06980
uniprot id: S6C800
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1423732:LBCZ RS02665
gene id: 1423732:LBCZ_RS02665
uniprot id: S6BQ23
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1423732:LBCZ RS02470
gene id: 1423732:LBCZ_RS02470
uniprot id: S6BW47
names: Similarity
messages: Belongs to the ThiD family.

1423732:LBCZ RS00430
gene id: 1423732:LBCZ_RS00430
uniprot id: S6CIS1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1423732:LBCZ RS05430
gene id: 1423732:LBCZ_RS05430
uniprot id: S6BXM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1423732:LBCZ RS00825
gene id: 1423732:LBCZ_RS00825
uniprot id: S6BNZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS04100
gene id: 1423732:LBCZ_RS04100
uniprot id: S6BX02
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

1423732:LBCZ RS00735
gene id: 1423732:LBCZ_RS00735
uniprot id: S6BVD3
names: Similarity
messages: Belongs to the ParB family.

1423732:LBCZ RS02410
gene id: 1423732:LBCZ_RS02410
uniprot id: S6C5T7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1423732:LBCZ RS10335
gene id: 1423732:LBCZ_RS10335
uniprot id: S6CBH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS02145
gene id: 1423732:LBCZ_RS02145
uniprot id: S6BVZ0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1423732:LBCZ RS10845
gene id: 1423732:LBCZ_RS10845
uniprot id: S6CJX4
names: Similarity
messages: Belongs to the peptidase C1 family.

1423732:LBCZ RS12055
gene id: 1423732:LBCZ_RS12055
uniprot id: S6C1Z0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.

1423732:LBCZ RS08465
gene id: 1423732:LBCZ_RS08465
uniprot id: S6C940
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1423732:LBCZ RS10990
gene id: 1423732:LBCZ_RS10990
uniprot id: S6C1C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1423732:LBCZ RS13255
gene id: 1423732:LBCZ_RS13255
uniprot id: S6CCH9
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1423732:LBCZ RS05595
gene id: 1423732:LBCZ_RS05595
uniprot id: S6BXW1
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1423732:LBCZ RS02890
gene id: 1423732:LBCZ_RS02890
uniprot id: S6C634
names: Similarity
messages: Belongs to the UPF0473 family.

1423732:LBCZ RS04510
gene id: 1423732:LBCZ_RS04510
uniprot id: S6BX58
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS05935
gene id: 1423732:LBCZ_RS05935
uniprot id: S6CJC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1423732:LBCZ RS05035
gene id: 1423732:LBCZ_RS05035
uniprot id: S6CJ93
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1423732:LBCZ RS10370
gene id: 1423732:LBCZ_RS10370
uniprot id: S6C9N0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1423732:LBCZ RS04365
gene id: 1423732:LBCZ_RS04365
uniprot id: S6C6M6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1423732:LBCZ RS10930
gene id: 1423732:LBCZ_RS10930
uniprot id: S6BUG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1423732:LBCZ RS09425
gene id: 1423732:LBCZ_RS09425
uniprot id: S6CB50
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1423732:LBCZ RS00525
gene id: 1423732:LBCZ_RS00525
uniprot id: S6C516
names: Similarity
messages: Belongs to the FGGY kinase family.

1423732:LBCZ RS09660
gene id: 1423732:LBCZ_RS09660
uniprot id: S6BTK2
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

1423732:LBCZ RS07505
gene id: 1423732:LBCZ_RS07505
uniprot id: S6BSD4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS02840
gene id: 1423732:LBCZ_RS02840
uniprot id: S6C629
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS06395
gene id: 1423732:LBCZ_RS06395
uniprot id: S6CJE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

1423732:LBCZ RS00150
gene id: 1423732:LBCZ_RS00150
uniprot id: S6BNP3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1423732:LBCZ RS14085
gene id: 1423732:LBCZ_RS14085
uniprot id: S6CCS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

1423732:LBCZ RS02715
gene id: 1423732:LBCZ_RS02715
uniprot id: S6C617
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1423732:LBCZ RS09745
gene id: 1423732:LBCZ_RS09745
uniprot id: S6CJT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

1423732:LBCZ RS06785
gene id: 1423732:LBCZ_RS06785
uniprot id: S6CJG4
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

1423732:LBCZ RS11835
gene id: 1423732:LBCZ_RS11835
uniprot id: S6CAA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1423732:LBCZ RS04170
gene id: 1423732:LBCZ_RS04170
uniprot id: S6CJ59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1423732:LBCZ RS09150
gene id: 1423732:LBCZ_RS09150
uniprot id: S6CB21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1423732:LBCZ RS03960
gene id: 1423732:LBCZ_RS03960
uniprot id: S6C9Q2
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1423732:LBCZ RS04220
gene id: 1423732:LBCZ_RS04220
uniprot id: S6CJ61
names: Similarity
messages: Belongs to the CinA family.

1423732:LBCZ RS05065
gene id: 1423732:LBCZ_RS05065
uniprot id: S6C6W6
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1423732:LBCZ RS00875
gene id: 1423732:LBCZ_RS00875
uniprot id: S6C563
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1423732:LBCZ RS07200
gene id: 1423732:LBCZ_RS07200
uniprot id: S6CAD1
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1423732:LBCZ RS09770
gene id: 1423732:LBCZ_RS09770
uniprot id: S6CJT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1423732:LBCZ RS13635
gene id: 1423732:LBCZ_RS13635
uniprot id: S6CAZ1
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1423732:LBCZ RS06955
gene id: 1423732:LBCZ_RS06955
uniprot id: S6C7Z8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS06345
gene id: 1423732:LBCZ_RS06345
uniprot id: S6CJE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

1423732:LBCZ RS02015
gene id: 1423732:LBCZ_RS02015
uniprot id: S6BVW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1423732:LBCZ RS09905
gene id: 1423732:LBCZ_RS09905
uniprot id: S6C0S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1423732:LBCZ RS07785
gene id: 1423732:LBCZ_RS07785
uniprot id: S6CJK3
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1423732:LBCZ RS04960
gene id: 1423732:LBCZ_RS04960
uniprot id: S6CJ90
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1423732:LBCZ RS08005
gene id: 1423732:LBCZ_RS08005
uniprot id: S6C8Z2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS02740
gene id: 1423732:LBCZ_RS02740
uniprot id: S6C618
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1423732:LBCZ RS09580
gene id: 1423732:LBCZ_RS09580
uniprot id: S6BTI7
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1423732:LBCZ RS02950
gene id: 1423732:LBCZ_RS02950
uniprot id: S6C9H6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1423732:LBCZ RS03630
gene id: 1423732:LBCZ_RS03630
uniprot id: S6C9N1
names: Similarity
messages: Belongs to the Fur family.

1423732:LBCZ RS05470
gene id: 1423732:LBCZ_RS05470
uniprot id: S6C7A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1423732:LBCZ RS00180
gene id: 1423732:LBCZ_RS00180
uniprot id: S6BNP6
names: Function
names: Similarity
messages: Belongs to the peptidase M20A family. N-acetyldiaminopimelate deacetylase subfamily.
messages: Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.

1423732:LBCZ RS08640
gene id: 1423732:LBCZ_RS08640
uniprot id: S6BT20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1423732:LBCZ RS04030
gene id: 1423732:LBCZ_RS04030
uniprot id: S6CJ54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS12660
gene id: 1423732:LBCZ_RS12660
uniprot id: S6CK44
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS04055
gene id: 1423732:LBCZ_RS04055
uniprot id: S6C6H5
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS07730
gene id: 1423732:LBCZ_RS07730
uniprot id: S6C889
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1423732:LBCZ RS02345
gene id: 1423732:LBCZ_RS02345
uniprot id: S6BW24
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS01480
gene id: 1423732:LBCZ_RS01480
uniprot id: S6CIW4
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1423732:LBCZ RS10380
gene id: 1423732:LBCZ_RS10380
uniprot id: S6C0Z7
names: Similarity
messages: Belongs to the UPF0177 family.

1423732:LBCZ RS00190
gene id: 1423732:LBCZ_RS00190
uniprot id: S6CIR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1423732:LBCZ RS04950
gene id: 1423732:LBCZ_RS04950
uniprot id: S6BR54
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1423732:LBCZ RS04545
gene id: 1423732:LBCZ_RS04545
uniprot id: S6C6Q5
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1423732:LBCZ RS07000
gene id: 1423732:LBCZ_RS07000
uniprot id: S6BS55
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1423732:LBCZ RS10225
gene id: 1423732:LBCZ_RS10225
uniprot id: S6C9L1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS13300
gene id: 1423732:LBCZ_RS13300
uniprot id: S6C2R4
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS08460
gene id: 1423732:LBCZ_RS08460
uniprot id: S6BSZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS00045
gene id: 1423732:LBCZ_RS00045
uniprot id: S6C878
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1423732:LBCZ RS00940
gene id: 1423732:LBCZ_RS00940
uniprot id: S6C8I8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1423732:LBCZ RS05440
gene id: 1423732:LBCZ_RS05440
uniprot id: S6BRF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1423732:LBCZ RS00195
gene id: 1423732:LBCZ_RS00195
uniprot id: S6BV72
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1423732:LBCZ RS01195
gene id: 1423732:LBCZ_RS01195
uniprot id: S6CIV1
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS05590
gene id: 1423732:LBCZ_RS05590
uniprot id: S6CJB5
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1423732:LBCZ RS01040
gene id: 1423732:LBCZ_RS01040
uniprot id: S6C593
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1423732:LBCZ RS07725
gene id: 1423732:LBCZ_RS07725
uniprot id: S6BSH7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS06480
gene id: 1423732:LBCZ_RS06480
uniprot id: S6CA61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1423732:LBCZ RS00030
gene id: 1423732:LBCZ_RS00030
uniprot id: S6C4R8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1423732:LBCZ RS05480
gene id: 1423732:LBCZ_RS05480
uniprot id: S6BXU0
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS04755
gene id: 1423732:LBCZ_RS04755
uniprot id: S6BX93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1423732:LBCZ RS11665
gene id: 1423732:LBCZ_RS11665
uniprot id: S6BUU8
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS12090
gene id: 1423732:LBCZ_RS12090
uniprot id: S6BV22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1423732:LBCZ RS02125
gene id: 1423732:LBCZ_RS02125
uniprot id: S6C8X6
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS01260
gene id: 1423732:LBCZ_RS01260
uniprot id: S6C8M1
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS05780
gene id: 1423732:LBCZ_RS05780
uniprot id: S6CJC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1423732:LBCZ RS06915
gene id: 1423732:LBCZ_RS06915
uniprot id: S6BYJ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1423732:LBCZ RS12100
gene id: 1423732:LBCZ_RS12100
uniprot id: S6CK21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. CshA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity.
messages: Oligomerizes, may be a member of the RNA degradosome.

1423732:LBCZ RS00135
gene id: 1423732:LBCZ_RS00135
uniprot id: S6CIR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS12220
gene id: 1423732:LBCZ_RS12220
uniprot id: S6CK26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS02930
gene id: 1423732:LBCZ_RS02930
uniprot id: S6BQ74
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-DCP.
messages: Belongs to the DltC family.
messages: Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
messages: Cytoplasm

1423732:LBCZ RS11175
gene id: 1423732:LBCZ_RS11175
uniprot id: S6C1H5
names: Subcellular Location Annotation
messages: cell wall

1423732:LBCZ RS13310
gene id: 1423732:LBCZ_RS13310
uniprot id: S6BVX9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.

1423732:LBCZ RS05515
gene id: 1423732:LBCZ_RS05515
uniprot id: S6BRI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Ycf16 family.
messages: Membrane

1423732:LBCZ RS11805
gene id: 1423732:LBCZ_RS11805
uniprot id: S6BUX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1423732:LBCZ RS12415
gene id: 1423732:LBCZ_RS12415
uniprot id: S6BV78
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1423732:LBCZ RS06380
gene id: 1423732:LBCZ_RS06380
uniprot id: S6CA54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

1423732:LBCZ RS09790
gene id: 1423732:LBCZ_RS09790
uniprot id: S6C9F2
names: Similarity
messages: Belongs to the fabD family.

1423732:LBCZ RS03075
gene id: 1423732:LBCZ_RS03075
uniprot id: S6C9I9
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS08275
gene id: 1423732:LBCZ_RS08275
uniprot id: S6CAV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

1423732:LBCZ RS05675
gene id: 1423732:LBCZ_RS05675
uniprot id: S6CA05
names: Similarity
messages: Belongs to the GST superfamily.

1423732:LBCZ RS11770
gene id: 1423732:LBCZ_RS11770
uniprot id: S6CK10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1423732:LBCZ RS09145
gene id: 1423732:LBCZ_RS09145
uniprot id: S6C0F3
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1423732:LBCZ RS11880
gene id: 1423732:LBCZ_RS11880
uniprot id: S6BUZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1423732:LBCZ RS07895
gene id: 1423732:LBCZ_RS07895
uniprot id: S6BZ49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS05905
gene id: 1423732:LBCZ_RS05905
uniprot id: S6C7H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS10355
gene id: 1423732:LBCZ_RS10355
uniprot id: S6C0Z3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1423732:LBCZ RS06710
gene id: 1423732:LBCZ_RS06710
uniprot id: S6C7W1
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1423732:LBCZ RS08545
gene id: 1423732:LBCZ_RS08545
uniprot id: S6CJN3
names: Similarity
messages: Belongs to the TPP enzyme family.

1423732:LBCZ RS02705
gene id: 1423732:LBCZ_RS02705
uniprot id: S6C9E8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1423732:LBCZ RS01440
gene id: 1423732:LBCZ_RS01440
uniprot id: S6C8P7
names: Similarity
messages: Belongs to the peptidase C59 family.

1423732:LBCZ RS14045
gene id: 1423732:LBCZ_RS14045
uniprot id: S6CB25
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

1423732:LBCZ RS05825
gene id: 1423732:LBCZ_RS05825
uniprot id: S6C7G6
names: Similarity
messages: Belongs to the UPF0758 family.

1423732:LBCZ RS06045
gene id: 1423732:LBCZ_RS06045
uniprot id: S6BRQ6
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1423732:LBCZ RS07245
gene id: 1423732:LBCZ_RS07245
uniprot id: S6BYR1
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1423732:LBCZ RS05095
gene id: 1423732:LBCZ_RS05095
uniprot id: S6CJ95
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS13220
gene id: 1423732:LBCZ_RS13220
uniprot id: S6CAV6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS02685
gene id: 1423732:LBCZ_RS02685
uniprot id: S6BQ35
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1423732:LBCZ RS04665
gene id: 1423732:LBCZ_RS04665
uniprot id: S6BQZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS06290
gene id: 1423732:LBCZ_RS06290
uniprot id: S6C7P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1423732:LBCZ RS07795
gene id: 1423732:LBCZ_RS07795
uniprot id: S6CAK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1423732:LBCZ RS07915
gene id: 1423732:LBCZ_RS07915
uniprot id: S6CJK8
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1423732:LBCZ RS08870
gene id: 1423732:LBCZ_RS08870
uniprot id: S6CJP5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1423732:LBCZ RS11130
gene id: 1423732:LBCZ_RS11130
uniprot id: S6CBU6
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

1423732:LBCZ RS07635
gene id: 1423732:LBCZ_RS07635
uniprot id: S6CJJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS01160
gene id: 1423732:LBCZ_RS01160
uniprot id: S6BP49
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1423732:LBCZ RS02835
gene id: 1423732:LBCZ_RS02835
uniprot id: S6BQ58
names: Similarity
messages: Belongs to the DtxR/MntR family.

1423732:LBCZ RS12150
gene id: 1423732:LBCZ_RS12150
uniprot id: S6C216
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

1423732:LBCZ RS04060
gene id: 1423732:LBCZ_RS04060
uniprot id: S6CJ55
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1423732:LBCZ RS06125
gene id: 1423732:LBCZ_RS06125
uniprot id: S6CJD7
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1423732:LBCZ RS01965
gene id: 1423732:LBCZ_RS01965
uniprot id: S6BPK7
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1423732:LBCZ RS04270
gene id: 1423732:LBCZ_RS04270
uniprot id: S6BX25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1423732:LBCZ RS06055
gene id: 1423732:LBCZ_RS06055
uniprot id: S6CJD4
names: Function
names: Similarity
names: Subunit
messages: A non-essential component of RNA polymerase (RNAP).
messages: Belongs to the RNA polymerase subunit epsilon family.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunit. The core is associated with a delta subunit, and at least one of epsilon or omega. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1423732:LBCZ RS13600
gene id: 1423732:LBCZ_RS13600
uniprot id: S6BW21
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1423732:LBCZ RS08520
gene id: 1423732:LBCZ_RS08520
uniprot id: S6CJN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1423732:LBCZ RS12020
gene id: 1423732:LBCZ_RS12020
uniprot id: S6CAC2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1423732:LBCZ RS08220
gene id: 1423732:LBCZ_RS08220
uniprot id: S6BZZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1423732:LBCZ RS07415
gene id: 1423732:LBCZ_RS07415
uniprot id: S6CJI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1423732:LBCZ RS07005
gene id: 1423732:LBCZ_RS07005
uniprot id: S6C804
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1423732:LBCZ RS08535
gene id: 1423732:LBCZ_RS08535
uniprot id: S6BT01
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1423732:LBCZ RS09775
gene id: 1423732:LBCZ_RS09775
uniprot id: S6C0Q5
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1423732:LBCZ RS12875
gene id: 1423732:LBCZ_RS12875
uniprot id: S6CCD3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rhamnose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
messages: Cytoplasm

1423732:LBCZ RS00040
gene id: 1423732:LBCZ_RS00040
uniprot id: S6BV40
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1423732:LBCZ RS10125
gene id: 1423732:LBCZ_RS10125
uniprot id: S6C9J5
names: Similarity
messages: Belongs to the peptidase C69 family.

1423732:LBCZ RS09420
gene id: 1423732:LBCZ_RS09420
uniprot id: S6C0K1
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1423732:LBCZ RS06550
gene id: 1423732:LBCZ_RS06550
uniprot id: S6BYD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1423732:LBCZ RS05415
gene id: 1423732:LBCZ_RS05415
uniprot id: S6BRD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1423732:LBCZ RS12900
gene id: 1423732:LBCZ_RS12900
uniprot id: S6BVH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1423732:LBCZ RS04225
gene id: 1423732:LBCZ_RS04225
uniprot id: S6BX20
names: Similarity
messages: Belongs to the RecA family.

1423732:LBCZ RS06500
gene id: 1423732:LBCZ_RS06500
uniprot id: S6BYC1
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1423732:LBCZ RS11145
gene id: 1423732:LBCZ_RS11145
uniprot id: S6CJY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS07290
gene id: 1423732:LBCZ_RS07290
uniprot id: S6CJI3
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1423732:LBCZ RS13980
gene id: 1423732:LBCZ_RS13980
uniprot id: S6CK97
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS13500
gene id: 1423732:LBCZ_RS13500
uniprot id: S6CCK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1423732:LBCZ RS13495
gene id: 1423732:LBCZ_RS13495
uniprot id: S6C2T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1423732:LBCZ RS04520
gene id: 1423732:LBCZ_RS04520
uniprot id: S6BQW1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1423732:LBCZ RS10650
gene id: 1423732:LBCZ_RS10650
uniprot id: S6C179
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1423732:LBCZ RS13305
gene id: 1423732:LBCZ_RS13305
uniprot id: S6CCI4
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS07585
gene id: 1423732:LBCZ_RS07585
uniprot id: S6CJJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1423732:LBCZ RS04155
gene id: 1423732:LBCZ_RS04155
uniprot id: S6C9R3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS02995
gene id: 1423732:LBCZ_RS02995
uniprot id: S6BWL8
names: Function
messages: Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.

1423732:LBCZ RS06770
gene id: 1423732:LBCZ_RS06770
uniprot id: S6CA87
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1423732:LBCZ RS05105
gene id: 1423732:LBCZ_RS05105
uniprot id: S6C9X0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1423732:LBCZ RS06140
gene id: 1423732:LBCZ_RS06140
uniprot id: S6BRS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1423732:LBCZ RS13135
gene id: 1423732:LBCZ_RS13135
uniprot id: S6BVV3
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

1423732:LBCZ RS06280
gene id: 1423732:LBCZ_RS06280
uniprot id: S6CA47
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

1423732:LBCZ RS10155
gene id: 1423732:LBCZ_RS10155
uniprot id: S6CJU6
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS10605
gene id: 1423732:LBCZ_RS10605
uniprot id: S6CBP1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1423732:LBCZ RS00795
gene id: 1423732:LBCZ_RS00795
uniprot id: S6BNY8
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1423732:LBCZ RS00445
gene id: 1423732:LBCZ_RS00445
uniprot id: S6C8D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS12435
gene id: 1423732:LBCZ_RS12435
uniprot id: S6CC89
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1423732:LBCZ RS13920
gene id: 1423732:LBCZ_RS13920
uniprot id: S6BW78
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS09480
gene id: 1423732:LBCZ_RS09480
uniprot id: S6BTH1
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS03595
gene id: 1423732:LBCZ_RS03595
uniprot id: S6CJ40
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS01585
gene id: 1423732:LBCZ_RS01585
uniprot id: S6C8R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS06850
gene id: 1423732:LBCZ_RS06850
uniprot id: S6BS34
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1423732:LBCZ RS07215
gene id: 1423732:LBCZ_RS07215
uniprot id: S6CJI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

1423732:LBCZ RS12230
gene id: 1423732:LBCZ_RS12230
uniprot id: S6CC67
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS02365
gene id: 1423732:LBCZ_RS02365
uniprot id: S6CIZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS05965
gene id: 1423732:LBCZ_RS05965
uniprot id: S6BY25
names: Subcellular Location Annotation
messages: Cytoplasm

1423732:LBCZ RS11380
gene id: 1423732:LBCZ_RS11380
uniprot id: S6BUN9
names: Similarity
messages: Belongs to the Dps family.

1423732:LBCZ RS03985
gene id: 1423732:LBCZ_RS03985
uniprot id: S6C6G3
names: Subcellular Location Annotation
messages: cell wall

1423732:LBCZ RS07465
gene id: 1423732:LBCZ_RS07465
uniprot id: S6CJJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1423732:LBCZ RS09995
gene id: 1423732:LBCZ_RS09995
uniprot id: S6C9H5
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1423732:LBCZ RS05870
gene id: 1423732:LBCZ_RS05870
uniprot id: S6BRN3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1423732:LBCZ RS08390
gene id: 1423732:LBCZ_RS08390
uniprot id: S6C931
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1423732:LBCZ RS02320
gene id: 1423732:LBCZ_RS02320
uniprot id: S6BW19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
messages: Cytoplasm

1423732:LBCZ RS04045
gene id: 1423732:LBCZ_RS04045
uniprot id: S6BQM4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS10010
gene id: 1423732:LBCZ_RS10010
uniprot id: S6CBD0
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

1423732:LBCZ RS11775
gene id: 1423732:LBCZ_RS11775
uniprot id: S6CC16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1423732:LBCZ RS08365
gene id: 1423732:LBCZ_RS08365
uniprot id: S6C930
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS06675
gene id: 1423732:LBCZ_RS06675
uniprot id: S6BS07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1423732:LBCZ RS10220
gene id: 1423732:LBCZ_RS10220
uniprot id: S6BTV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

1423732:LBCZ RS07235
gene id: 1423732:LBCZ_RS07235
uniprot id: S6C838
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1423732:LBCZ RS02000
gene id: 1423732:LBCZ_RS02000
uniprot id: S6C5P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS00705
gene id: 1423732:LBCZ_RS00705
uniprot id: S6CIT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

1423732:LBCZ RS04150
gene id: 1423732:LBCZ_RS04150
uniprot id: S6BX10
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

1423732:LBCZ RS07840
gene id: 1423732:LBCZ_RS07840
uniprot id: S6CJK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S15 family.
messages: Cytoplasm
messages: Homodimer.
messages: Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.

1423732:LBCZ RS09375
gene id: 1423732:LBCZ_RS09375
uniprot id: S6CB43
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1423732:LBCZ RS07475
gene id: 1423732:LBCZ_RS07475
uniprot id: S6CAG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1423732:LBCZ RS04340
gene id: 1423732:LBCZ_RS04340
uniprot id: S6CJ66
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1423732:LBCZ RS13280
gene id: 1423732:LBCZ_RS13280
uniprot id: S6CCI1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS05915
gene id: 1423732:LBCZ_RS05915
uniprot id: S6BY15
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS04215
gene id: 1423732:LBCZ_RS04215
uniprot id: S6C6K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1423732:LBCZ RS12780
gene id: 1423732:LBCZ_RS12780
uniprot id: S6CCC6
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1423732:LBCZ RS05885
gene id: 1423732:LBCZ_RS05885
uniprot id: S6CJC7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1423732:LBCZ RS07800
gene id: 1423732:LBCZ_RS07800
uniprot id: S6BSJ2
names: Similarity
messages: Belongs to the peptidase M24B family.

1423732:LBCZ RS00270
gene id: 1423732:LBCZ_RS00270
uniprot id: S6BV81
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

1423732:LBCZ RS13015
gene id: 1423732:LBCZ_RS13015
uniprot id: S6CAT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1423732:LBCZ RS11140
gene id: 1423732:LBCZ_RS11140
uniprot id: S6CA46
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1423732:LBCZ RS00410
gene id: 1423732:LBCZ_RS00410
uniprot id: S6BV97
names: Similarity
messages: Belongs to the peptidase S66 family.

1423732:LBCZ RS08925
gene id: 1423732:LBCZ_RS08925
uniprot id: S6C0A5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CitD family.
messages: Covalent carrier of the coenzyme of citrate lyase.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.

1423732:LBCZ RS08665
gene id: 1423732:LBCZ_RS08665
uniprot id: S6BT25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1423732:LBCZ RS10460
gene id: 1423732:LBCZ_RS10460
uniprot id: S6CBJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YabA family.
messages: Interacts with both DnaA and DnaN, acting as a bridge between these two proteins.
messages: Involved in initiation control of chromosome replication.

1423732:LBCZ RS06755
gene id: 1423732:LBCZ_RS06755
uniprot id: S6C7W9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS09180
gene id: 1423732:LBCZ_RS09180
uniprot id: S6BTB5
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS11795
gene id: 1423732:LBCZ_RS11795
uniprot id: S6C1V1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1423732:LBCZ RS01185
gene id: 1423732:LBCZ_RS01185
uniprot id: S6BP51
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

1423732:LBCZ RS11375
gene id: 1423732:LBCZ_RS11375
uniprot id: S6CBW7
names: Similarity
messages: Belongs to the UPF0177 family.

1423732:LBCZ RS12305
gene id: 1423732:LBCZ_RS12305
uniprot id: S6C248
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS00745
gene id: 1423732:LBCZ_RS00745
uniprot id: S6BNY3
names: Similarity
messages: Belongs to the ParB family.

1423732:LBCZ RS10620
gene id: 1423732:LBCZ_RS10620
uniprot id: S6CJW5
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1423732:LBCZ RS05420
gene id: 1423732:LBCZ_RS05420
uniprot id: S6C754
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1423732:LBCZ RS02795
gene id: 1423732:LBCZ_RS02795
uniprot id: S6CJ14
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1423732:LBCZ RS05810
gene id: 1423732:LBCZ_RS05810
uniprot id: S6BY00
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1423732:LBCZ RS05970
gene id: 1423732:LBCZ_RS05970
uniprot id: S6CA24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1423732:LBCZ RS11825
gene id: 1423732:LBCZ_RS11825
uniprot id: S6CC23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1423732:LBCZ RS08420
gene id: 1423732:LBCZ_RS08420
uniprot id: S6CJM8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS04580
gene id: 1423732:LBCZ_RS04580
uniprot id: S6BX70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS04395
gene id: 1423732:LBCZ_RS04395
uniprot id: S6CJ68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1423732:LBCZ RS04735
gene id: 1423732:LBCZ_RS04735
uniprot id: S6C9V3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1423732:LBCZ RS06940
gene id: 1423732:LBCZ_RS06940
uniprot id: S6BYK3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 2 subfamily.
messages: Heterodimer of AddA and RexB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' -> 3' nuclease activity.

1423732:LBCZ RS10025
gene id: 1423732:LBCZ_RS10025
uniprot id: S6CJU1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1423732:LBCZ RS02820
gene id: 1423732:LBCZ_RS02820
uniprot id: S6CJ15
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1423732:LBCZ RS01525
gene id: 1423732:LBCZ_RS01525
uniprot id: S6C5I8
names: Similarity
messages: Belongs to the TPP enzyme family.

1423732:LBCZ RS04230
gene id: 1423732:LBCZ_RS04230
uniprot id: S6C9R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

1423732:LBCZ RS09440
gene id: 1423732:LBCZ_RS09440
uniprot id: S6CJR8
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1423732:LBCZ RS09805
gene id: 1423732:LBCZ_RS09805
uniprot id: S6CBA4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1423732:LBCZ RS00420
gene id: 1423732:LBCZ_RS00420
uniprot id: S6BNS8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1423732:LBCZ RS04610
gene id: 1423732:LBCZ_RS04610
uniprot id: S6C9U4
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1423732:LBCZ RS05655
gene id: 1423732:LBCZ_RS05655
uniprot id: S6BRK0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1423732:LBCZ RS06130
gene id: 1423732:LBCZ_RS06130
uniprot id: S6BY53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0298 family.
messages: Cytoplasm

1423732:LBCZ RS12045
gene id: 1423732:LBCZ_RS12045
uniprot id: S6CAC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1423732:LBCZ RS10560
gene id: 1423732:LBCZ_RS10560
uniprot id: S6CBN6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS08760
gene id: 1423732:LBCZ_RS08760
uniprot id: S6CJP2
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS08425
gene id: 1423732:LBCZ_RS08425
uniprot id: S6C021
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1423732:LBCZ RS06590
gene id: 1423732:LBCZ_RS06590
uniprot id: S6C7U6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

1423732:LBCZ RS12015
gene id: 1423732:LBCZ_RS12015
uniprot id: S6BV07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

1423732:LBCZ RS11080
gene id: 1423732:LBCZ_RS11080
uniprot id: S6BUI8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1423732:LBCZ RS07980
gene id: 1423732:LBCZ_RS07980
uniprot id: S6C8Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

1423732:LBCZ RS06685
gene id: 1423732:LBCZ_RS06685
uniprot id: S6CJG0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1423732:LBCZ RS06680
gene id: 1423732:LBCZ_RS06680
uniprot id: S6C7V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1423732:LBCZ RS02260
gene id: 1423732:LBCZ_RS02260
uniprot id: S6CIZ3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1423732:LBCZ RS12325
gene id: 1423732:LBCZ_RS12325
uniprot id: S6CK30
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

1423732:LBCZ RS00655
gene id: 1423732:LBCZ_RS00655
uniprot id: S6CIT0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1423732:LBCZ RS06905
gene id: 1423732:LBCZ_RS06905
uniprot id: S6C7Y7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS09175
gene id: 1423732:LBCZ_RS09175
uniprot id: S6CB24
names: Function
names: Similarity
messages: Belongs to the CpsD/CapB family.
messages: Involved in the regulation of capsular polysaccharide biosynthesis. Autophosphorylation of CpsD attenuates its activity and reduces the level of encapsulation. May be part of a complex that directs the coordinated polymerization and export to the cell surface of the capsular polysaccharide.

1423732:LBCZ RS07675
gene id: 1423732:LBCZ_RS07675
uniprot id: S6BSG5
names: Similarity
messages: Belongs to the asp23 family.

1423732:LBCZ RS05930
gene id: 1423732:LBCZ_RS05930
uniprot id: S6C7I2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1423732:LBCZ RS06105
gene id: 1423732:LBCZ_RS06105
uniprot id: S6CJD6
names: Similarity
messages: Belongs to the UPF0223 family.

1423732:LBCZ RS11710
gene id: 1423732:LBCZ_RS11710
uniprot id: S6CC05
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1423732:LBCZ RS09415
gene id: 1423732:LBCZ_RS09415
uniprot id: S6CJR7
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1423732:LBCZ RS09730
gene id: 1423732:LBCZ_RS09730
uniprot id: S6CB94
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS09605
gene id: 1423732:LBCZ_RS09605
uniprot id: S6BTJ3
names: Similarity
messages: Belongs to the UPF0246 family.

1423732:LBCZ RS05950
gene id: 1423732:LBCZ_RS05950
uniprot id: S6BRP4
names: Subcellular Location Annotation
messages: Cytoplasm

1423732:LBCZ RS02300
gene id: 1423732:LBCZ_RS02300
uniprot id: S6C909
names: Activity Regulation
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), including enzyme I, and histidine-containing protein (HPr) are required for the phosphorylation, which leads to the activation of the enzyme.

1423732:LBCZ RS11155
gene id: 1423732:LBCZ_RS11155
uniprot id: S6CBU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1423732:LBCZ RS05510
gene id: 1423732:LBCZ_RS05510
uniprot id: S6C9Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS06560
gene id: 1423732:LBCZ_RS06560
uniprot id: S6BRY8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1423732:LBCZ RS12365
gene id: 1423732:LBCZ_RS12365
uniprot id: S6BV70
names: Similarity
messages: Belongs to the GppA/Ppx family.

1423732:LBCZ RS00900
gene id: 1423732:LBCZ_RS00900
uniprot id: S6C567
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1423732:LBCZ RS01520
gene id: 1423732:LBCZ_RS01520
uniprot id: S6BPC5
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1423732:LBCZ RS10785
gene id: 1423732:LBCZ_RS10785
uniprot id: S6BUE5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1423732:LBCZ RS12250
gene id: 1423732:LBCZ_RS12250
uniprot id: S6C238
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

1423732:LBCZ RS09760
gene id: 1423732:LBCZ_RS09760
uniprot id: S6BTL9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS05435
gene id: 1423732:LBCZ_RS05435
uniprot id: S6C9Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1423732:LBCZ RS11995
gene id: 1423732:LBCZ_RS11995
uniprot id: S6CAB9
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1423732:LBCZ RS05425
gene id: 1423732:LBCZ_RS05425
uniprot id: S6CJA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1423732:LBCZ RS13350
gene id: 1423732:LBCZ_RS13350
uniprot id: S6C2R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS09360
gene id: 1423732:LBCZ_RS09360
uniprot id: S6C9B3
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

1423732:LBCZ RS05385
gene id: 1423732:LBCZ_RS05385
uniprot id: S6C9Y1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1423732:LBCZ RS05535
gene id: 1423732:LBCZ_RS05535
uniprot id: S6C9Z0
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1423732:LBCZ RS05205
gene id: 1423732:LBCZ_RS05205
uniprot id: S6BRA0
names: Similarity
messages: Belongs to the glycosyl hydrolase 73 family.

1423732:LBCZ RS01350
gene id: 1423732:LBCZ_RS01350
uniprot id: S6CIV8
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1423732:LBCZ RS12560
gene id: 1423732:LBCZ_RS12560
uniprot id: S6CAJ3
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

1423732:LBCZ RS04930
gene id: 1423732:LBCZ_RS04930
uniprot id: S6C6V1
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1423732:LBCZ RS07450
gene id: 1423732:LBCZ_RS07450
uniprot id: S6CAG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1423732:LBCZ RS01625
gene id: 1423732:LBCZ_RS01625
uniprot id: S6BPE6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1423732:LBCZ RS04905
gene id: 1423732:LBCZ_RS04905
uniprot id: S6C6U8
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1423732:LBCZ RS04495
gene id: 1423732:LBCZ_RS04495
uniprot id: S6BQV5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1423732:LBCZ RS05325
gene id: 1423732:LBCZ_RS05325
uniprot id: S6BXJ8
names: Similarity
messages: Belongs to the peptidase C69 family.

1423732:LBCZ RS06660
gene id: 1423732:LBCZ_RS06660
uniprot id: S6CJF9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1423732:LBCZ RS06750
gene id: 1423732:LBCZ_RS06750
uniprot id: S6BS18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1423732:LBCZ RS06545
gene id: 1423732:LBCZ_RS06545
uniprot id: S6CJF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1423732:LBCZ RS04485
gene id: 1423732:LBCZ_RS04485
uniprot id: S6BX55
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1423732:LBCZ RS08025
gene id: 1423732:LBCZ_RS08025
uniprot id: S6BSR3
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1423732:LBCZ RS07975
gene id: 1423732:LBCZ_RS07975
uniprot id: S6BSQ4
names: Similarity
messages: Belongs to the acylphosphatase family.

1423732:LBCZ RS04730
gene id: 1423732:LBCZ_RS04730
uniprot id: S6BX89
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1423732:LBCZ RS13605
gene id: 1423732:LBCZ_RS13605
uniprot id: S6CAY9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS05835
gene id: 1423732:LBCZ_RS05835
uniprot id: S6BY05
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1423732:LBCZ RS08430
gene id: 1423732:LBCZ_RS08430
uniprot id: S6CAW6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1423732:LBCZ RS00005
gene id: 1423732:LBCZ_RS00005
uniprot id: S6C4R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1423732:LBCZ RS01110
gene id: 1423732:LBCZ_RS01110
uniprot id: S6BP33
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1423732:LBCZ RS08385
gene id: 1423732:LBCZ_RS08385
uniprot id: S6BSX5
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

1423732:LBCZ RS08410
gene id: 1423732:LBCZ_RS08410
uniprot id: S6BSY0
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1423732:LBCZ RS04955
gene id: 1423732:LBCZ_RS04955
uniprot id: S6C6V4
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1423732:LBCZ RS00790
gene id: 1423732:LBCZ_RS00790
uniprot id: S6C8H0
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1423732:LBCZ RS11885
gene id: 1423732:LBCZ_RS11885
uniprot id: S6CAB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1423732:LBCZ RS06180
gene id: 1423732:LBCZ_RS06180
uniprot id: S6BY62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1423732:LBCZ RS01495
gene id: 1423732:LBCZ_RS01495
uniprot id: S6BPB8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS04300
gene id: 1423732:LBCZ_RS04300
uniprot id: S6C9S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1423732:LBCZ RS12665
gene id: 1423732:LBCZ_RS12665
uniprot id: S6C2D8
names: Similarity
messages: Belongs to the catalase family.

1423732:LBCZ RS04725
gene id: 1423732:LBCZ_RS04725
uniprot id: S6CJ81
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1423732:LBCZ RS10925
gene id: 1423732:LBCZ_RS10925
uniprot id: S6CBS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1423732:LBCZ RS11830
gene id: 1423732:LBCZ_RS11830
uniprot id: S6BUY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1423732:LBCZ RS05320
gene id: 1423732:LBCZ_RS05320
uniprot id: S6CJA4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS06575
gene id: 1423732:LBCZ_RS06575
uniprot id: S6BYD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1423732:LBCZ RS08400
gene id: 1423732:LBCZ_RS08400
uniprot id: S6C018
names: Similarity
messages: Belongs to the GARS family.

1423732:LBCZ RS04065
gene id: 1423732:LBCZ_RS04065
uniprot id: S6BWZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

1423732:LBCZ RS06585
gene id: 1423732:LBCZ_RS06585
uniprot id: S6BRZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1423732:LBCZ RS12870
gene id: 1423732:LBCZ_RS12870
uniprot id: S6C2H1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aldolase class II family. RhaD subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
messages: Cytoplasm

1423732:LBCZ RS07615
gene id: 1423732:LBCZ_RS07615
uniprot id: S6BYY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1423732:LBCZ RS00100
gene id: 1423732:LBCZ_RS00100
uniprot id: S6C4W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

1423732:LBCZ RS02845
gene id: 1423732:LBCZ_RS02845
uniprot id: S6CJ16
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1423732:LBCZ RS02540
gene id: 1423732:LBCZ_RS02540
uniprot id: S6BW74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1423732:LBCZ RS10055
gene id: 1423732:LBCZ_RS10055
uniprot id: S6CJU2
names: Similarity
messages: Belongs to the asparagine synthetase family.

1423732:LBCZ RS00770
gene id: 1423732:LBCZ_RS00770
uniprot id: S6BNY5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1423732:LBCZ RS00240
gene id: 1423732:LBCZ_RS00240
uniprot id: S6C4Y3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1423732:LBCZ RS06190
gene id: 1423732:LBCZ_RS06190
uniprot id: S6BRS9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS12595
gene id: 1423732:LBCZ_RS12595
uniprot id: S6BVB2
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

1423732:LBCZ RS04500
gene id: 1423732:LBCZ_RS04500
uniprot id: S6C6P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1423732:LBCZ RS00805
gene id: 1423732:LBCZ_RS00805
uniprot id: S6CIT6
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1423732:LBCZ RS15045
gene id: 1423732:LBCZ_RS15045
uniprot id: S6C1T3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1423732:LBCZ RS04965
gene id: 1423732:LBCZ_RS04965
uniprot id: S6BXC8
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1423732:LBCZ RS04130
gene id: 1423732:LBCZ_RS04130
uniprot id: S6C9R1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1423732:LBCZ RS10450
gene id: 1423732:LBCZ_RS10450
uniprot id: S6CJV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: chloroplast

1423732:LBCZ RS12940
gene id: 1423732:LBCZ_RS12940
uniprot id: S6C2H9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinone-dependent D-lactate dehydrogenase family.
messages: Catalyzes the oxidation of D-lactate to pyruvate.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS02095
gene id: 1423732:LBCZ_RS02095
uniprot id: S6BVY3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS04550
gene id: 1423732:LBCZ_RS04550
uniprot id: S6CJ74
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

1423732:LBCZ RS09655
gene id: 1423732:LBCZ_RS09655
uniprot id: S6CB82
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS12525
gene id: 1423732:LBCZ_RS12525
uniprot id: S6C293
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1423732:LBCZ RS06880
gene id: 1423732:LBCZ_RS06880
uniprot id: S6C7Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GpsB family.
messages: Cytoplasm
messages: Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
messages: Forms polymers through the coiled coil domains. Interacts with PBP1, MreC and EzrA.

1423732:LBCZ RS04985
gene id: 1423732:LBCZ_RS04985
uniprot id: S6CJ91
names: Similarity
messages: Belongs to the peptidase M13 family.

1423732:LBCZ RS13180
gene id: 1423732:LBCZ_RS13180
uniprot id: S6C2P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS07695
gene id: 1423732:LBCZ_RS07695
uniprot id: S6CAJ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1423732:LBCZ RS07155
gene id: 1423732:LBCZ_RS07155
uniprot id: S6C824
names: Function
names: Similarity
messages: Belongs to the transposase IS30 family.
messages: Required for the transposition of the insertion element.

1423732:LBCZ RS00065
gene id: 1423732:LBCZ_RS00065
uniprot id: S6BV46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1423732:LBCZ RS05390
gene id: 1423732:LBCZ_RS05390
uniprot id: S6BRD4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1423732:LBCZ RS10070
gene id: 1423732:LBCZ_RS10070
uniprot id: S6BTS9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1423732:LBCZ RS08340
gene id: 1423732:LBCZ_RS08340
uniprot id: S6C929
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MecA family.
messages: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
messages: Homodimer.
messages: The N-terminal domain probably binds unfolded/aggregated proteins; the C-terminal domain interacts with ClpC.

1423732:LBCZ RS11555
gene id: 1423732:LBCZ_RS11555
uniprot id: S6CBY5
names: Similarity
messages: Belongs to the peptidase C40 family.

1423732:LBCZ RS08445
gene id: 1423732:LBCZ_RS08445
uniprot id: S6CJM9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS11920
gene id: 1423732:LBCZ_RS11920
uniprot id: S6CC33
names: Similarity
messages: Belongs to the CtsR family.

1423732:LBCZ RS04180
gene id: 1423732:LBCZ_RS04180
uniprot id: S6C9R5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS12225
gene id: 1423732:LBCZ_RS12225
uniprot id: S6C233
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1423732:LBCZ RS06095
gene id: 1423732:LBCZ_RS06095
uniprot id: S6BRR3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1423732:LBCZ RS09430
gene id: 1423732:LBCZ_RS09430
uniprot id: S6BTG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1423732:LBCZ RS10920
gene id: 1423732:LBCZ_RS10920
uniprot id: S6C1B0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS05405
gene id: 1423732:LBCZ_RS05405
uniprot id: S6BXL1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS12265
gene id: 1423732:LBCZ_RS12265
uniprot id: S6CAF9
names: Similarity
messages: Belongs to the aldolase LacD family.

1423732:LBCZ RS06835
gene id: 1423732:LBCZ_RS06835
uniprot id: S6CJG6
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

1423732:LBCZ RS05855
gene id: 1423732:LBCZ_RS05855
uniprot id: S6CJC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS07950
gene id: 1423732:LBCZ_RS07950
uniprot id: S6CAT2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1423732:LBCZ RS03045
gene id: 1423732:LBCZ_RS03045
uniprot id: S6BWM6
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1423732:LBCZ RS06470
gene id: 1423732:LBCZ_RS06470
uniprot id: S6CJF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS01645
gene id: 1423732:LBCZ_RS01645
uniprot id: S6BPF1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1423732:LBCZ RS06775
gene id: 1423732:LBCZ_RS06775
uniprot id: S6BS23
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1423732:LBCZ RS08305
gene id: 1423732:LBCZ_RS08305
uniprot id: S6BSW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1423732:LBCZ RS07880
gene id: 1423732:LBCZ_RS07880
uniprot id: S6BSL1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1423732:LBCZ RS12575
gene id: 1423732:LBCZ_RS12575
uniprot id: S6BVA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS08285
gene id: 1423732:LBCZ_RS08285
uniprot id: S6C922
names: Similarity
messages: Belongs to the UPF0342 family.

1423732:LBCZ RS02510
gene id: 1423732:LBCZ_RS02510
uniprot id: S6CJ03
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS10530
gene id: 1423732:LBCZ_RS10530
uniprot id: S6C164
names: Similarity
messages: Belongs to the peptidase S8 family.

1423732:LBCZ RS07445
gene id: 1423732:LBCZ_RS07445
uniprot id: S6BYV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1423732:LBCZ RS08150
gene id: 1423732:LBCZ_RS08150
uniprot id: S6C908
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1423732:LBCZ RS08435
gene id: 1423732:LBCZ_RS08435
uniprot id: S6BSY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1423732:LBCZ RS12765
gene id: 1423732:LBCZ_RS12765
uniprot id: S6CAM4
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS09055
gene id: 1423732:LBCZ_RS09055
uniprot id: S6C0D7
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1423732:LBCZ RS10405
gene id: 1423732:LBCZ_RS10405
uniprot id: S6C101
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1423732:LBCZ RS00880
gene id: 1423732:LBCZ_RS00880
uniprot id: S6CIT9
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1423732:LBCZ RS14190
gene id: 1423732:LBCZ_RS14190
uniprot id: S6CKA6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1423732:LBCZ RS05380
gene id: 1423732:LBCZ_RS05380
uniprot id: S6BXK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

1423732:LBCZ RS00060
gene id: 1423732:LBCZ_RS00060
uniprot id: S6CIQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS12820
gene id: 1423732:LBCZ_RS12820
uniprot id: S6C2G2
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1423732:LBCZ RS05700
gene id: 1423732:LBCZ_RS05700
uniprot id: S6BRK7
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS12010
gene id: 1423732:LBCZ_RS12010
uniprot id: S6CC35
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1423732:LBCZ RS06175
gene id: 1423732:LBCZ_RS06175
uniprot id: S6CJD9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1423732:LBCZ RS07640
gene id: 1423732:LBCZ_RS07640
uniprot id: S6BYZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS09535
gene id: 1423732:LBCZ_RS09535
uniprot id: S6C9C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS12915
gene id: 1423732:LBCZ_RS12915
uniprot id: S6C2H6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

1423732:LBCZ RS11790
gene id: 1423732:LBCZ_RS11790
uniprot id: S6CK11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1423732:LBCZ RS09350
gene id: 1423732:LBCZ_RS09350
uniprot id: S6CB40
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1423732:LBCZ RS11220
gene id: 1423732:LBCZ_RS11220
uniprot id: S6CJY9
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1423732:LBCZ RS07645
gene id: 1423732:LBCZ_RS07645
uniprot id: S6CAI4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1423732:LBCZ RS00515
gene id: 1423732:LBCZ_RS00515
uniprot id: S6C8D9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1423732:LBCZ RS07655
gene id: 1423732:LBCZ_RS07655
uniprot id: S6C885
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1423732:LBCZ RS08160
gene id: 1423732:LBCZ_RS08160
uniprot id: S6BZY4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1423732:LBCZ RS08740
gene id: 1423732:LBCZ_RS08740
uniprot id: S6CJP1
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

1423732:LBCZ RS10020
gene id: 1423732:LBCZ_RS10020
uniprot id: S6C9I0
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS03055
gene id: 1423732:LBCZ_RS03055
uniprot id: S6BQ93
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.

1423732:LBCZ RS05900
gene id: 1423732:LBCZ_RS05900
uniprot id: S6BRN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS02535
gene id: 1423732:LBCZ_RS02535
uniprot id: S6CJ04
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS07375
gene id: 1423732:LBCZ_RS07375
uniprot id: S6BYT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1423732:LBCZ RS06820
gene id: 1423732:LBCZ_RS06820
uniprot id: S6CA91
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1423732:LBCZ RS06315
gene id: 1423732:LBCZ_RS06315
uniprot id: S6C7Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1423732:LBCZ RS13935
gene id: 1423732:LBCZ_RS13935
uniprot id: S6C2Z7
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1423732:LBCZ RS00185
gene id: 1423732:LBCZ_RS00185
uniprot id: S6C4X7
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

1423732:LBCZ RS07300
gene id: 1423732:LBCZ_RS07300
uniprot id: S6CAE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1423732:LBCZ RS07430
gene id: 1423732:LBCZ_RS07430
uniprot id: S6BSC1
names: Similarity
messages: Belongs to the ribF family.

1423732:LBCZ RS12795
gene id: 1423732:LBCZ_RS12795
uniprot id: S6C2F8
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1423732:LBCZ RS06245
gene id: 1423732:LBCZ_RS06245
uniprot id: S6CJE2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1423732:LBCZ RS00280
gene id: 1423732:LBCZ_RS00280
uniprot id: S6BNQ8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1423732:LBCZ RS07285
gene id: 1423732:LBCZ_RS07285
uniprot id: S6C847
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1423732:LBCZ RS12200
gene id: 1423732:LBCZ_RS12200
uniprot id: S6C229
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1423732:LBCZ RS11730
gene id: 1423732:LBCZ_RS11730
uniprot id: S6CC10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1423732:LBCZ RS01330
gene id: 1423732:LBCZ_RS01330
uniprot id: S6BVL3
names: Subcellular Location Annotation
messages: Cytoplasm

1423732:LBCZ RS11765
gene id: 1423732:LBCZ_RS11765
uniprot id: S6CA95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1423732:LBCZ RS09355
gene id: 1423732:LBCZ_RS09355
uniprot id: S6BTE7
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1423732:LBCZ RS08615
gene id: 1423732:LBCZ_RS08615
uniprot id: S6BT16
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS04400
gene id: 1423732:LBCZ_RS04400
uniprot id: S6BX44
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1423732:LBCZ RS07660
gene id: 1423732:LBCZ_RS07660
uniprot id: S6CJJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1423732:LBCZ RS00530
gene id: 1423732:LBCZ_RS00530
uniprot id: S6CIS5
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1423732:LBCZ RS04260
gene id: 1423732:LBCZ_RS04260
uniprot id: S6C6L0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1423732:LBCZ RS05620
gene id: 1423732:LBCZ_RS05620
uniprot id: S6BXW6
names: Similarity
messages: Belongs to the DCK/DGK family.

1423732:LBCZ RS07260
gene id: 1423732:LBCZ_RS07260
uniprot id: S6C844
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS00800
gene id: 1423732:LBCZ_RS00800
uniprot id: S6C547
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS06260
gene id: 1423732:LBCZ_RS06260
uniprot id: S6BRU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS11840
gene id: 1423732:LBCZ_RS11840
uniprot id: S6CK13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1423732:LBCZ RS07405
gene id: 1423732:LBCZ_RS07405
uniprot id: S6BSB6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1423732:LBCZ RS07690
gene id: 1423732:LBCZ_RS07690
uniprot id: S6BZ02
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1423732:LBCZ RS07790
gene id: 1423732:LBCZ_RS07790
uniprot id: S6BZ21
names: Similarity
messages: Belongs to the asp23 family.

1423732:LBCZ RS04890
gene id: 1423732:LBCZ_RS04890
uniprot id: S6BXB5
names: Similarity
messages: Belongs to the UPF0735 family.

1423732:LBCZ RS00665
gene id: 1423732:LBCZ_RS00665
uniprot id: S6C8F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1423732:LBCZ RS02150
gene id: 1423732:LBCZ_RS02150
uniprot id: S6C8X9
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1423732:LBCZ RS11590
gene id: 1423732:LBCZ_RS11590
uniprot id: S6CA79
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1423732:LBCZ RS12440
gene id: 1423732:LBCZ_RS12440
uniprot id: S6BV83
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS13165
gene id: 1423732:LBCZ_RS13165
uniprot id: S6BVV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1423732:LBCZ RS02210
gene id: 1423732:LBCZ_RS02210
uniprot id: S6CIZ1
names: Similarity
messages: Belongs to the UPF0145 family.

1423732:LBCZ RS02885
gene id: 1423732:LBCZ_RS02885
uniprot id: S6BQ67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1423732:LBCZ RS02340
gene id: 1423732:LBCZ_RS02340
uniprot id: S6CIZ6
names: Subcellular Location Annotation
messages: Cytoplasm

1423732:LBCZ RS14075
gene id: 1423732:LBCZ_RS14075
uniprot id: S6CKA1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS11750
gene id: 1423732:LBCZ_RS11750
uniprot id: S6C1T8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1423732:LBCZ RS06800
gene id: 1423732:LBCZ_RS06800
uniprot id: S6BS27
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1423732:LBCZ RS09650
gene id: 1423732:LBCZ_RS09650
uniprot id: S6C0P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1423732:LBCZ RS12050
gene id: 1423732:LBCZ_RS12050
uniprot id: S6CK19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1423732:LBCZ RS03065
gene id: 1423732:LBCZ_RS03065
uniprot id: S6CJ25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS14050
gene id: 1423732:LBCZ_RS14050
uniprot id: S6CKA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1423732:LBCZ RS06350
gene id: 1423732:LBCZ_RS06350
uniprot id: S6BY93
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS07220
gene id: 1423732:LBCZ_RS07220
uniprot id: S6BYQ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1423732:LBCZ RS06070
gene id: 1423732:LBCZ_RS06070
uniprot id: S6BRR0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1423732:LBCZ RS10600
gene id: 1423732:LBCZ_RS10600
uniprot id: S6C173
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1423732:LBCZ RS07855
gene id: 1423732:LBCZ_RS07855
uniprot id: S6BSK5
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1423732:LBCZ RS10030
gene id: 1423732:LBCZ_RS10030
uniprot id: S6C0T9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1423732:LBCZ RS05615
gene id: 1423732:LBCZ_RS05615
uniprot id: S6CJB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1423732:LBCZ RS08295
gene id: 1423732:LBCZ_RS08295
uniprot id: S6C003
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1423732:LBCZ RS05500
gene id: 1423732:LBCZ_RS05500
uniprot id: S6CJB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1423732:LBCZ RS02380
gene id: 1423732:LBCZ_RS02380
uniprot id: S6BPT9
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

1423732:LBCZ RS07905
gene id: 1423732:LBCZ_RS07905
uniprot id: S6BSL7
names: Similarity
messages: Belongs to the HesB/IscA family.

1423732:LBCZ RS04020
gene id: 1423732:LBCZ_RS04020
uniprot id: S6BQM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS06035
gene id: 1423732:LBCZ_RS06035
uniprot id: S6BY36
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1423732:LBCZ RS04145
gene id: 1423732:LBCZ_RS04145
uniprot id: S6CJ58
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS05815
gene id: 1423732:LBCZ_RS05815
uniprot id: S6CA15
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1423732:LBCZ RS09985
gene id: 1423732:LBCZ_RS09985
uniprot id: S6CBC5
names: Similarity
messages: Belongs to the threonine synthase family.

1423732:LBCZ RS10545
gene id: 1423732:LBCZ_RS10545
uniprot id: S6C9Z3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1423732:LBCZ RS08310
gene id: 1423732:LBCZ_RS08310
uniprot id: S6C925
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1423732:LBCZ RS08845
gene id: 1423732:LBCZ_RS08845
uniprot id: S6CJP4
names: Similarity
messages: Belongs to the TPP enzyme family.

1423732:LBCZ RS07270
gene id: 1423732:LBCZ_RS07270
uniprot id: S6BYR5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1423732:LBCZ RS04635
gene id: 1423732:LBCZ_RS04635
uniprot id: S6C9U6
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1423732:LBCZ RS08470
gene id: 1423732:LBCZ_RS08470
uniprot id: S6CJN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HPr family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
messages: P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity.

1423732:LBCZ RS09080
gene id: 1423732:LBCZ_RS09080
uniprot id: S6C0E1
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

1423732:LBCZ RS04745
gene id: 1423732:LBCZ_RS04745
uniprot id: S6C6T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1423732:LBCZ RS07710
gene id: 1423732:LBCZ_RS07710
uniprot id: S6CJK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1423732:LBCZ RS04095
gene id: 1423732:LBCZ_RS04095
uniprot id: S6CJ56
names: Similarity
messages: Belongs to the UPF0237 family.

1423732:LBCZ RS07760
gene id: 1423732:LBCZ_RS07760
uniprot id: S6CJK2
names: Similarity
messages: Belongs to the TlyA family.

1423732:LBCZ RS04080
gene id: 1423732:LBCZ_RS04080
uniprot id: S6C9Q8
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1423732:LBCZ RS14040
gene id: 1423732:LBCZ_RS14040
uniprot id: S6BW99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1423732:LBCZ RS06690
gene id: 1423732:LBCZ_RS06690
uniprot id: S6BYG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1423732:LBCZ RS10420
gene id: 1423732:LBCZ_RS10420
uniprot id: S6C9N9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1423732:LBCZ RS04505
gene id: 1423732:LBCZ_RS04505
uniprot id: S6CJ72
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1423732:LBCZ RS05795
gene id: 1423732:LBCZ_RS05795
uniprot id: S6BRM2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1423732:LBCZ RS10320
gene id: 1423732:LBCZ_RS10320
uniprot id: S6BTX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1423732:LBCZ RS04135
gene id: 1423732:LBCZ_RS04135
uniprot id: S6BQN8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1423732:LBCZ RS10635
gene id: 1423732:LBCZ_RS10635
uniprot id: S6BUC2
names: Similarity
names: Subunit
messages: Belongs to the class II ribonucleoside-triphosphate reductase family.
messages: Monomer.

1423732:LBCZ RS10665
gene id: 1423732:LBCZ_RS10665
uniprot id: S6CJW7
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS05560
gene id: 1423732:LBCZ_RS05560
uniprot id: S6C7C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1423732:LBCZ RS04940
gene id: 1423732:LBCZ_RS04940
uniprot id: S6BXC4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1423732:LBCZ RS02385
gene id: 1423732:LBCZ_RS02385
uniprot id: S6C5T4
names: Similarity
messages: Belongs to the aldolase LacD family.

1423732:LBCZ RS01670
gene id: 1423732:LBCZ_RS01670
uniprot id: S6BPF8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS05570
gene id: 1423732:LBCZ_RS05570
uniprot id: S6BXV7
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1423732:LBCZ RS11800
gene id: 1423732:LBCZ_RS11800
uniprot id: S6CC20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1423732:LBCZ RS08345
gene id: 1423732:LBCZ_RS08345
uniprot id: S6CJM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArsC family. Spx subfamily.
messages: Cytoplasm
messages: Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes. Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP). This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.
messages: Interacts with the C-terminal domain of the alpha subunit of the RNAP.

1423732:LBCZ RS12040
gene id: 1423732:LBCZ_RS12040
uniprot id: S6BV12
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS07495
gene id: 1423732:LBCZ_RS07495
uniprot id: S6BYV9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1423732:LBCZ RS01080
gene id: 1423732:LBCZ_RS01080
uniprot id: S6C8J9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS06425
gene id: 1423732:LBCZ_RS06425
uniprot id: S6BYA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1423732:LBCZ RS04380
gene id: 1423732:LBCZ_RS04380
uniprot id: S6C9S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1423732:LBCZ RS07625
gene id: 1423732:LBCZ_RS07625
uniprot id: S6BSF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1423732:LBCZ RS08495
gene id: 1423732:LBCZ_RS08495
uniprot id: S6CJN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1423732:LBCZ RS09570
gene id: 1423732:LBCZ_RS09570
uniprot id: S6C0N0
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1423732:LBCZ RS01075
gene id: 1423732:LBCZ_RS01075
uniprot id: S6BVH9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1423732:LBCZ RS07945
gene id: 1423732:LBCZ_RS07945
uniprot id: S6BZT9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1423732:LBCZ RS09390
gene id: 1423732:LBCZ_RS09390
uniprot id: S6CJR6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS09885
gene id: 1423732:LBCZ_RS09885
uniprot id: S6CBB3
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1423732:LBCZ RS11700
gene id: 1423732:LBCZ_RS11700
uniprot id: S6CK07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS08660
gene id: 1423732:LBCZ_RS08660
uniprot id: S6CAY4
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1423732:LBCZ RS11725
gene id: 1423732:LBCZ_RS11725
uniprot id: S6CK08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1423732:LBCZ RS07650
gene id: 1423732:LBCZ_RS07650
uniprot id: S6BSG0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1423732:LBCZ RS07805
gene id: 1423732:LBCZ_RS07805
uniprot id: S6C8A8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1423732:LBCZ RS05215
gene id: 1423732:LBCZ_RS05215
uniprot id: S6CJA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1423732:LBCZ RS02630
gene id: 1423732:LBCZ_RS02630
uniprot id: S6C958
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1423732:LBCZ RS06565
gene id: 1423732:LBCZ_RS06565
uniprot id: S6C7T5
names: Similarity
messages: Belongs to the ClpX chaperone family. HslU subfamily.

1423732:LBCZ RS05940
gene id: 1423732:LBCZ_RS05940
uniprot id: S6BY21
names: Similarity
messages: Belongs to the YggT family.

1423732:LBCZ RS09940
gene id: 1423732:LBCZ_RS09940
uniprot id: S6BTQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS09215
gene id: 1423732:LBCZ_RS09215
uniprot id: S6CJQ9
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1423732:LBCZ RS04345
gene id: 1423732:LBCZ_RS04345
uniprot id: S6BX35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1423732:LBCZ RS11415
gene id: 1423732:LBCZ_RS11415
uniprot id: S6CA70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS10110
gene id: 1423732:LBCZ_RS10110
uniprot id: S6C0V1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers).

1423732:LBCZ RS09115
gene id: 1423732:LBCZ_RS09115
uniprot id: S6BT99
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS02225
gene id: 1423732:LBCZ_RS02225
uniprot id: S6BPR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS08245
gene id: 1423732:LBCZ_RS08245
uniprot id: S6BZZ5
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

1423732:LBCZ RS09990
gene id: 1423732:LBCZ_RS09990
uniprot id: S6BTR2
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1423732:LBCZ RS07485
gene id: 1423732:LBCZ_RS07485
uniprot id: S6C875
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1423732:LBCZ RS00755
gene id: 1423732:LBCZ_RS00755
uniprot id: S6CIT4
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1423732:LBCZ RS07775
gene id: 1423732:LBCZ_RS07775
uniprot id: S6BSI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1423732:LBCZ RS05195
gene id: 1423732:LBCZ_RS05195
uniprot id: S6BXH3
names: Subcellular Location Annotation
messages: Cytoplasm

1423732:LBCZ RS06235
gene id: 1423732:LBCZ_RS06235
uniprot id: S6BRT6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1423732:LBCZ RS11860
gene id: 1423732:LBCZ_RS11860
uniprot id: S6CAA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm

1423732:LBCZ RS10350
gene id: 1423732:LBCZ_RS10350
uniprot id: S6CJV4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1423732:LBCZ RS09460
gene id: 1423732:LBCZ_RS09460
uniprot id: S6C9B8
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS07575
gene id: 1423732:LBCZ_RS07575
uniprot id: S6BSE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1423732:LBCZ RS13045
gene id: 1423732:LBCZ_RS13045
uniprot id: S6CK59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS07510
gene id: 1423732:LBCZ_RS07510
uniprot id: S6C877
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1423732:LBCZ RS06780
gene id: 1423732:LBCZ_RS06780
uniprot id: S6C7X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1423732:LBCZ RS09545
gene id: 1423732:LBCZ_RS09545
uniprot id: S6C0M6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS04615
gene id: 1423732:LBCZ_RS04615
uniprot id: S6BQY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1423732:LBCZ RS04575
gene id: 1423732:LBCZ_RS04575
uniprot id: S6CJ75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS10105
gene id: 1423732:LBCZ_RS10105
uniprot id: S6CJU4
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1423732:LBCZ RS10900
gene id: 1423732:LBCZ_RS10900
uniprot id: S6CBS3
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1423732:LBCZ RS10825
gene id: 1423732:LBCZ_RS10825
uniprot id: S6C197
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1423732:LBCZ RS05925
gene id: 1423732:LBCZ_RS05925
uniprot id: S6BRP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Belongs to the heat shock protein 70 family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1423732:LBCZ RS08715
gene id: 1423732:LBCZ_RS08715
uniprot id: S6C964
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS02130
gene id: 1423732:LBCZ_RS02130
uniprot id: S6BPN8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS07570
gene id: 1423732:LBCZ_RS07570
uniprot id: S6CAH6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1423732:LBCZ RS00905
gene id: 1423732:LBCZ_RS00905
uniprot id: S6CIU0
names: Similarity
messages: Belongs to the FGGY kinase family.

1423732:LBCZ RS12210
gene id: 1423732:LBCZ_RS12210
uniprot id: S6BV44
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS06330
gene id: 1423732:LBCZ_RS06330
uniprot id: S6CA50
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1423732:LBCZ RS04705
gene id: 1423732:LBCZ_RS04705
uniprot id: S6BX86
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS05080
gene id: 1423732:LBCZ_RS05080
uniprot id: S6C9W9
names: Similarity
messages: Belongs to the peptidase M29 family.

1423732:LBCZ RS04535
gene id: 1423732:LBCZ_RS04535
uniprot id: S6C9T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1423732:LBCZ RS04125
gene id: 1423732:LBCZ_RS04125
uniprot id: S6BX06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS07410
gene id: 1423732:LBCZ_RS07410
uniprot id: S6C863
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1423732:LBCZ RS07470
gene id: 1423732:LBCZ_RS07470
uniprot id: S6BYV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1423732:LBCZ RS10115
gene id: 1423732:LBCZ_RS10115
uniprot id: S6CBE4
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS12370
gene id: 1423732:LBCZ_RS12370
uniprot id: S6CAH4
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1423732:LBCZ RS12410
gene id: 1423732:LBCZ_RS12410
uniprot id: S6C268
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1423732:LBCZ RS07500
gene id: 1423732:LBCZ_RS07500
uniprot id: S6CAG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1423732:LBCZ RS02830
gene id: 1423732:LBCZ_RS02830
uniprot id: S6C9F9
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

1423732:LBCZ RS12590
gene id: 1423732:LBCZ_RS12590
uniprot id: S6CCA8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1423732:LBCZ RS00860
gene id: 1423732:LBCZ_RS00860
uniprot id: S6BVF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family.
messages: Homotetramer.
messages: Involved in the oxidation of myo-inositol (MI) and D-chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively.

1423732:LBCZ RS08505
gene id: 1423732:LBCZ_RS08505
uniprot id: S6CAX2
names: Similarity
messages: Belongs to the acetyltransferase family.

1423732:LBCZ RS06765
gene id: 1423732:LBCZ_RS06765
uniprot id: S6BYH4
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1423732:LBCZ RS07720
gene id: 1423732:LBCZ_RS07720
uniprot id: S6CAJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1423732:LBCZ RS13525
gene id: 1423732:LBCZ_RS13525
uniprot id: S6BW10
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1423732:LBCZ RS07490
gene id: 1423732:LBCZ_RS07490
uniprot id: S6CJJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1423732:LBCZ RS13745
gene id: 1423732:LBCZ_RS13745
uniprot id: S6C2W9
names: Similarity
messages: Belongs to the glycosyl hydrolase 73 family.
messages: Belongs to the peptidase C40 family.

1423732:LBCZ RS11635
gene id: 1423732:LBCZ_RS11635
uniprot id: S6CBZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1423732:LBCZ RS07765
gene id: 1423732:LBCZ_RS07765
uniprot id: S6BZ15
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1423732:LBCZ RS08075
gene id: 1423732:LBCZ_RS08075
uniprot id: S6BSS2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1423732:LBCZ RS10360
gene id: 1423732:LBCZ_RS10360
uniprot id: S6CBH3
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS02390
gene id: 1423732:LBCZ_RS02390
uniprot id: S6CIZ8
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1423732:LBCZ RS13095
gene id: 1423732:LBCZ_RS13095
uniprot id: S6CK61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1423732:LBCZ RS01575
gene id: 1423732:LBCZ_RS01575
uniprot id: S6CIW8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1423732:LBCZ RS01300
gene id: 1423732:LBCZ_RS01300
uniprot id: S6CIV6
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS03575
gene id: 1423732:LBCZ_RS03575
uniprot id: S6C9M5
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1423732:LBCZ RS05850
gene id: 1423732:LBCZ_RS05850
uniprot id: S6C7G9
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

1423732:LBCZ RS05750
gene id: 1423732:LBCZ_RS05750
uniprot id: S6C7F7
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS02135
gene id: 1423732:LBCZ_RS02135
uniprot id: S6C5Q9
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1423732:LBCZ RS10535
gene id: 1423732:LBCZ_RS10535
uniprot id: S6CBN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

1423732:LBCZ RS08915
gene id: 1423732:LBCZ_RS08915
uniprot id: S6C974
names: Subcellular Location Annotation
messages: Cytoplasm

1423732:LBCZ RS07210
gene id: 1423732:LBCZ_RS07210
uniprot id: S6C833
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1423732:LBCZ RS08330
gene id: 1423732:LBCZ_RS08330
uniprot id: S6CAW0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS05450
gene id: 1423732:LBCZ_RS05450
uniprot id: S6CJA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1423732:LBCZ RS00730
gene id: 1423732:LBCZ_RS00730
uniprot id: S6CIT3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1423732:LBCZ RS12425
gene id: 1423732:LBCZ_RS12425
uniprot id: S6CK34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS05830
gene id: 1423732:LBCZ_RS05830
uniprot id: S6CJC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1423732:LBCZ RS06670
gene id: 1423732:LBCZ_RS06670
uniprot id: S6CA80
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1423732:LBCZ RS02290
gene id: 1423732:LBCZ_RS02290
uniprot id: S6CIZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1423732:LBCZ RS06090
gene id: 1423732:LBCZ_RS06090
uniprot id: S6CA31
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1423732:LBCZ RS13580
gene id: 1423732:LBCZ_RS13580
uniprot id: S6CAY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1423732:LBCZ RS09945
gene id: 1423732:LBCZ_RS09945
uniprot id: S6C9G7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1423732:LBCZ RS07590
gene id: 1423732:LBCZ_RS07590
uniprot id: S6BYY2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1423732:LBCZ RS02395
gene id: 1423732:LBCZ_RS02395
uniprot id: S6BW31
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1423732:LBCZ RS07030
gene id: 1423732:LBCZ_RS07030
uniprot id: S6C811
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1423732:LBCZ RS10455
gene id: 1423732:LBCZ_RS10455
uniprot id: S6C155
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1423732:LBCZ RS07715
gene id: 1423732:LBCZ_RS07715
uniprot id: S6BZ07
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1423732:LBCZ RS10840
gene id: 1423732:LBCZ_RS10840
uniprot id: S6CA16
names: Similarity
messages: Belongs to the peptidase C1 family.

1423732:LBCZ RS06455
gene id: 1423732:LBCZ_RS06455
uniprot id: S6CA60
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
messages: Homodimer.

1423732:LBCZ RS08745
gene id: 1423732:LBCZ_RS08745
uniprot id: S6CAZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1423732:LBCZ RS06505
gene id: 1423732:LBCZ_RS06505
uniprot id: S6CA63
names: Similarity
messages: Belongs to the UPF0346 family.

1423732:LBCZ RS02880
gene id: 1423732:LBCZ_RS02880
uniprot id: S6C9G8
names: Similarity
messages: Belongs to the UPF0297 family.

1423732:LBCZ RS12135
gene id: 1423732:LBCZ_RS12135
uniprot id: S6BV32
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1423732:LBCZ RS09320
gene id: 1423732:LBCZ_RS09320
uniprot id: S6CJR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1423732:LBCZ RS02430
gene id: 1423732:LBCZ_RS02430
uniprot id: S6BPV4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1423732:LBCZ RS11905
gene id: 1423732:LBCZ_RS11905
uniprot id: S6CAB4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1423732:LBCZ RS09950
gene id: 1423732:LBCZ_RS09950
uniprot id: S6CJT8
names: Similarity
messages: Belongs to the SfsA family.

1423732:LBCZ RS00010
gene id: 1423732:LBCZ_RS00010
uniprot id: S6CIQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1423732:LBCZ RS06115
gene id: 1423732:LBCZ_RS06115
uniprot id: S6CA33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1423732:LBCZ RS08440
gene id: 1423732:LBCZ_RS08440
uniprot id: S6C937
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1423732:LBCZ RS00200
gene id: 1423732:LBCZ_RS00200
uniprot id: S6C8A2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS08550
gene id: 1423732:LBCZ_RS08550
uniprot id: S6C038
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

1423732:LBCZ RS00995
gene id: 1423732:LBCZ_RS00995
uniprot id: S6BP19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS12330
gene id: 1423732:LBCZ_RS12330
uniprot id: S6C253
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

1423732:LBCZ RS09005
gene id: 1423732:LBCZ_RS09005
uniprot id: S6C0C8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS06385
gene id: 1423732:LBCZ_RS06385
uniprot id: S6BRW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

1423732:LBCZ RS07755
gene id: 1423732:LBCZ_RS07755
uniprot id: S6C8A0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1423732:LBCZ RS06050
gene id: 1423732:LBCZ_RS06050
uniprot id: S6C7K5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1423732:LBCZ RS06450
gene id: 1423732:LBCZ_RS06450
uniprot id: S6BYB3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS02315
gene id: 1423732:LBCZ_RS02315
uniprot id: S6CIZ5
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1423732:LBCZ RS11760
gene id: 1423732:LBCZ_RS11760
uniprot id: S6BUW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1423732:LBCZ RS02905
gene id: 1423732:LBCZ_RS02905
uniprot id: S6BQ70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1423732:LBCZ RS01335
gene id: 1423732:LBCZ_RS01335
uniprot id: S6C8N1
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS05495
gene id: 1423732:LBCZ_RS05495
uniprot id: S6C7B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1423732:LBCZ RS12310
gene id: 1423732:LBCZ_RS12310
uniprot id: S6CC77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cell envelope
messages: Releases the N-terminal proline from various substrates.

1423732:LBCZ RS10475
gene id: 1423732:LBCZ_RS10475
uniprot id: S6CJV9
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1423732:LBCZ RS10595
gene id: 1423732:LBCZ_RS10595
uniprot id: S6CJW4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1423732:LBCZ RS13770
gene id: 1423732:LBCZ_RS13770
uniprot id: S6CCN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1423732:LBCZ RS04410
gene id: 1423732:LBCZ_RS04410
uniprot id: S6BQT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1423732:LBCZ RS04320
gene id: 1423732:LBCZ_RS04320
uniprot id: S6BX33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1423732:LBCZ RS06300
gene id: 1423732:LBCZ_RS06300
uniprot id: S6BY85
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1423732:LBCZ RS07370
gene id: 1423732:LBCZ_RS07370
uniprot id: S6CJI6
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1423732:LBCZ RS04250
gene id: 1423732:LBCZ_RS04250
uniprot id: S6C9R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1423732:LBCZ RS09265
gene id: 1423732:LBCZ_RS09265
uniprot id: S6CJR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS07890
gene id: 1423732:LBCZ_RS07890
uniprot id: S6CJK7
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS03040
gene id: 1423732:LBCZ_RS03040
uniprot id: S6CJ24
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1423732:LBCZ RS09060
gene id: 1423732:LBCZ_RS09060
uniprot id: S6CB15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

1423732:LBCZ RS06760
gene id: 1423732:LBCZ_RS06760
uniprot id: S6CJG3
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS01660
gene id: 1423732:LBCZ_RS01660
uniprot id: S6BVR5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS04015
gene id: 1423732:LBCZ_RS04015
uniprot id: S6C9Q5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1423732:LBCZ RS04945
gene id: 1423732:LBCZ_RS04945
uniprot id: S6C9W4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1423732:LBCZ RS01225
gene id: 1423732:LBCZ_RS01225
uniprot id: S6C8L5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1423732:LBCZ RS03610
gene id: 1423732:LBCZ_RS03610
uniprot id: S6BQF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS10375
gene id: 1423732:LBCZ_RS10375
uniprot id: S6CJV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1423732:LBCZ RS06795
gene id: 1423732:LBCZ_RS06795
uniprot id: S6CA89
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1423732:LBCZ RS09550
gene id: 1423732:LBCZ_RS09550
uniprot id: S6CB65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1423732:LBCZ RS00050
gene id: 1423732:LBCZ_RS00050
uniprot id: S6BNJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1423732:LBCZ RS07515
gene id: 1423732:LBCZ_RS07515
uniprot id: S6CJJ2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1423732:LBCZ RS08415
gene id: 1423732:LBCZ_RS08415
uniprot id: S6C933
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1423732:LBCZ RS07205
gene id: 1423732:LBCZ_RS07205
uniprot id: S6BS83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1423732:LBCZ RS10385
gene id: 1423732:LBCZ_RS10385
uniprot id: S6CBH7
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1423732:LBCZ RS07010
gene id: 1423732:LBCZ_RS07010
uniprot id: S6CJH3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1423732:LBCZ RS00535
gene id: 1423732:LBCZ_RS00535
uniprot id: S6BVB1
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS08955
gene id: 1423732:LBCZ_RS08955
uniprot id: S6C0A9
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS11065
gene id: 1423732:LBCZ_RS11065
uniprot id: S6CJY3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1423732:LBCZ RS12000
gene id: 1423732:LBCZ_RS12000
uniprot id: S6CK17
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1423732:LBCZ RS02275
gene id: 1423732:LBCZ_RS02275
uniprot id: S6BPS0
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1423732:LBCZ RS09395
gene id: 1423732:LBCZ_RS09395
uniprot id: S6C0J7
names: Similarity
messages: Belongs to the FBPase class 3 family.

1423732:LBCZ RS04605
gene id: 1423732:LBCZ_RS04605
uniprot id: S6BX74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1423732:LBCZ RS04190
gene id: 1423732:LBCZ_RS04190
uniprot id: S6C6J7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1423732:LBCZ RS15610
gene id: 1423732:LBCZ_RS15610
uniprot id: S6CAN9
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1423732:LBCZ RS07845
gene id: 1423732:LBCZ_RS07845
uniprot id: S6BZ32
names: Similarity
messages: Belongs to the glutamine synthetase family.

1423732:LBCZ RS02460
gene id: 1423732:LBCZ_RS02460
uniprot id: S6C5U4
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1423732:LBCZ RS02925
gene id: 1423732:LBCZ_RS02925
uniprot id: S6C9H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Cell membrane
messages: Membrane
messages: O-acyltransferase that catalyzes D-alanylation of both teichoic acid and lipoteichoic acid (LTA). D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Catalyzes D-alanylation from DltC carrier protein.

1423732:LBCZ RS06960
gene id: 1423732:LBCZ_RS06960
uniprot id: S6CJH1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1423732:LBCZ RS08835
gene id: 1423732:LBCZ_RS08835
uniprot id: S6BT47
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS02650
gene id: 1423732:LBCZ_RS02650
uniprot id: S6CJ08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS02295
gene id: 1423732:LBCZ_RS02295
uniprot id: S6BW15
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1423732:LBCZ RS08500
gene id: 1423732:LBCZ_RS08500
uniprot id: S6C030
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1423732:LBCZ RS04715
gene id: 1423732:LBCZ_RS04715
uniprot id: S6BR05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Cell membrane
messages: Probably a homodimer.

1423732:LBCZ RS02050
gene id: 1423732:LBCZ_RS02050
uniprot id: S6C8W9
names: Similarity
messages: Belongs to the EamA transporter family.

1423732:LBCZ RS13070
gene id: 1423732:LBCZ_RS13070
uniprot id: S6CK60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1423732:LBCZ RS09925
gene id: 1423732:LBCZ_RS09925
uniprot id: S6CJT7
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1423732:LBCZ RS05210
gene id: 1423732:LBCZ_RS05210
uniprot id: S6C6Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

1423732:LBCZ RS05030
gene id: 1423732:LBCZ_RS05030
uniprot id: S6C6W3
names: Similarity
messages: Belongs to the DEAD box helicase family.

1423732:LBCZ RS10765
gene id: 1423732:LBCZ_RS10765
uniprot id: S6CA08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

1423732:LBCZ RS10655
gene id: 1423732:LBCZ_RS10655
uniprot id: S6CBP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1423732:LBCZ RS01990
gene id: 1423732:LBCZ_RS01990
uniprot id: S6C8W3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1423732:LBCZ RS06930
gene id: 1423732:LBCZ_RS06930
uniprot id: S6C7Z0
names: Function
names: Similarity
messages: 3'-5' exonuclease.
messages: Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.

1423732:LBCZ RS09595
gene id: 1423732:LBCZ_RS09595
uniprot id: S6C0N5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1423732:LBCZ RS02850
gene id: 1423732:LBCZ_RS02850
uniprot id: S6BWJ2
names: Similarity
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

1423732:LBCZ RS05445
gene id: 1423732:LBCZ_RS05445
uniprot id: S6C7A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1423732:LBCZ RS07250
gene id: 1423732:LBCZ_RS07250
uniprot id: S6CAD6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1423732:LBCZ RS04140
gene id: 1423732:LBCZ_RS04140
uniprot id: S6C6I9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

1423732:LBCZ RS00680
gene id: 1423732:LBCZ_RS00680
uniprot id: S6CIT1
names: Similarity
messages: Belongs to the asp23 family.

1423732:LBCZ RS06275
gene id: 1423732:LBCZ_RS06275
uniprot id: S6BY80
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1423732:LBCZ RS06595
gene id: 1423732:LBCZ_RS06595
uniprot id: S6CJF6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

1423732:LBCZ RS06840
gene id: 1423732:LBCZ_RS06840
uniprot id: S6BYI6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1423732:LBCZ RS05250
gene id: 1423732:LBCZ_RS05250
uniprot id: S6C9X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRP transporter (TC 2.A.7.5) family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS11785
gene id: 1423732:LBCZ_RS11785
uniprot id: S6CA97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1423732:LBCZ RS09750
gene id: 1423732:LBCZ_RS09750
uniprot id: S6C0Q1
names: Similarity
messages: Belongs to the CFA/CMAS family.

1423732:LBCZ RS11720
gene id: 1423732:LBCZ_RS11720
uniprot id: S6CA90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1423732:LBCZ RS13975
gene id: 1423732:LBCZ_RS13975
uniprot id: S6CB20
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

1423732:LBCZ RS09525
gene id: 1423732:LBCZ_RS09525
uniprot id: S6CB63
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1423732:LBCZ RS02075
gene id: 1423732:LBCZ_RS02075
uniprot id: S6C8X2
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1423732:LBCZ RS09125
gene id: 1423732:LBCZ_RS09125
uniprot id: S6CJQ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aldolase class II family. RhaD subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
messages: Cytoplasm

1423732:LBCZ RS03615
gene id: 1423732:LBCZ_RS03615
uniprot id: S6C6C3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1423732:LBCZ RS04295
gene id: 1423732:LBCZ_RS04295
uniprot id: S6BX28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1423732:LBCZ RS07480
gene id: 1423732:LBCZ_RS07480
uniprot id: S6BSC9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1423732:LBCZ RS02165
gene id: 1423732:LBCZ_RS02165
uniprot id: S6CIY9
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1423732:LBCZ RS03870
gene id: 1423732:LBCZ_RS03870
uniprot id: S6BQJ4
names: Similarity
messages: Belongs to the peptidase S14 family.

1423732:LBCZ RS09875
gene id: 1423732:LBCZ_RS09875
uniprot id: S6CJT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS00275
gene id: 1423732:LBCZ_RS00275
uniprot id: S6C8B9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1423732:LBCZ RS07940
gene id: 1423732:LBCZ_RS07940
uniprot id: S6CJK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1423732:LBCZ RS07435
gene id: 1423732:LBCZ_RS07435
uniprot id: S6C869
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1423732:LBCZ RS02330
gene id: 1423732:LBCZ_RS02330
uniprot id: S6BPT0
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1423732:LBCZ RS15050
gene id: 1423732:LBCZ_RS15050
uniprot id: S6C1U7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1423732:LBCZ RS09315
gene id: 1423732:LBCZ_RS09315
uniprot id: S6C9A8
names: Similarity
messages: Belongs to the peptidase C40 family.

1423732:LBCZ RS07995
gene id: 1423732:LBCZ_RS07995
uniprot id: S6CAT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1423732:LBCZ RS02285
gene id: 1423732:LBCZ_RS02285
uniprot id: S6C5S4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1423732:LBCZ RS09140
gene id: 1423732:LBCZ_RS09140
uniprot id: S6CJQ6
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS01435
gene id: 1423732:LBCZ_RS01435
uniprot id: S6CIW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1423732:LBCZ RS14090
gene id: 1423732:LBCZ_RS14090
uniprot id: S6BWA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1423732:LBCZ RS06950
gene id: 1423732:LBCZ_RS06950
uniprot id: S6BS49
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

1423732:LBCZ RS06240
gene id: 1423732:LBCZ_RS06240
uniprot id: S6C7P1
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1423732:LBCZ RS01200
gene id: 1423732:LBCZ_RS01200
uniprot id: S6BVJ6
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS10130
gene id: 1423732:LBCZ_RS10130
uniprot id: S6CJU5
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1423732:LBCZ RS09010
gene id: 1423732:LBCZ_RS09010
uniprot id: S6CB11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS11755
gene id: 1423732:LBCZ_RS11755
uniprot id: S6CC13
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1423732:LBCZ RS05225
gene id: 1423732:LBCZ_RS05225
uniprot id: S6C9X5
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1423732:LBCZ RS11735
gene id: 1423732:LBCZ_RS11735
uniprot id: S6BUW2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1423732:LBCZ RS03805
gene id: 1423732:LBCZ_RS03805
uniprot id: S6C6E3
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1423732:LBCZ RS05485
gene id: 1423732:LBCZ_RS05485
uniprot id: S6C9Y6
names: Similarity
messages: Belongs to the GcvH family.

1423732:LBCZ RS08165
gene id: 1423732:LBCZ_RS08165
uniprot id: S6CAU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1423732:LBCZ RS04390
gene id: 1423732:LBCZ_RS04390
uniprot id: S6C6M9
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1423732:LBCZ RS07865
gene id: 1423732:LBCZ_RS07865
uniprot id: S6CJK6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1423732:LBCZ RS11820
gene id: 1423732:LBCZ_RS11820
uniprot id: S6C1V8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1423732:LBCZ RS07750
gene id: 1423732:LBCZ_RS07750
uniprot id: S6BSI2
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1423732:LBCZ RS08965
gene id: 1423732:LBCZ_RS08965
uniprot id: S6BT70
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

1423732:LBCZ RS09980
gene id: 1423732:LBCZ_RS09980
uniprot id: S6C0T1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1423732:LBCZ RS05890
gene id: 1423732:LBCZ_RS05890
uniprot id: S6BY12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1423732:LBCZ RS05525
gene id: 1423732:LBCZ_RS05525
uniprot id: S6CJB2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1423732:LBCZ RS10695
gene id: 1423732:LBCZ_RS10695
uniprot id: S6CBQ1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1423732:LBCZ RS05410
gene id: 1423732:LBCZ_RS05410
uniprot id: S6C9Y2
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1423732:LBCZ RS08555
gene id: 1423732:LBCZ_RS08555
uniprot id: S6CAX6
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1423732:LBCZ RS10485
gene id: 1423732:LBCZ_RS10485
uniprot id: S6CBM7
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1423732:LBCZ RS02110
gene id: 1423732:LBCZ_RS02110
uniprot id: S6C5Q6
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS04800
gene id: 1423732:LBCZ_RS04800
uniprot id: S6CJ84
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS10550
gene id: 1423732:LBCZ_RS10550
uniprot id: S6CJW2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS12140
gene id: 1423732:LBCZ_RS12140
uniprot id: S6CAE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS06845
gene id: 1423732:LBCZ_RS06845
uniprot id: S6CA93
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

1423732:LBCZ RS05960
gene id: 1423732:LBCZ_RS05960
uniprot id: S6CJD0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1423732:LBCZ RS06555
gene id: 1423732:LBCZ_RS06555
uniprot id: S6CA67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1423732:LBCZ RS09475
gene id: 1423732:LBCZ_RS09475
uniprot id: S6CB57
names: Function
names: Similarity
messages: Belongs to the CpsD/CapB family.
messages: Involved in the regulation of capsular polysaccharide biosynthesis. Autophosphorylation of CpsD attenuates its activity and reduces the level of encapsulation. May be part of a complex that directs the coordinated polymerization and export to the cell surface of the capsular polysaccharide.

1423732:LBCZ RS04350
gene id: 1423732:LBCZ_RS04350
uniprot id: S6C9S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1423732:LBCZ RS04750
gene id: 1423732:LBCZ_RS04750
uniprot id: S6CJ82
names: Similarity
messages: Belongs to the GSP E family.

1423732:LBCZ RS05910
gene id: 1423732:LBCZ_RS05910
uniprot id: S6CJC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1423732:LBCZ RS02805
gene id: 1423732:LBCZ_RS02805
uniprot id: S6C9F8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1423732:LBCZ RS10660
gene id: 1423732:LBCZ_RS10660
uniprot id: S6CA02
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS02935
gene id: 1423732:LBCZ_RS02935
uniprot id: S6C639
names: Similarity
messages: Belongs to the DltD family.

1423732:LBCZ RS14020
gene id: 1423732:LBCZ_RS14020
uniprot id: S6BW95
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS06935
gene id: 1423732:LBCZ_RS06935
uniprot id: S6CJH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

1423732:LBCZ RS00055
gene id: 1423732:LBCZ_RS00055
uniprot id: S6C4R9
names: Similarity
messages: Belongs to the peptidase C56 family.

1423732:LBCZ RS06005
gene id: 1423732:LBCZ_RS06005
uniprot id: S6CJD2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1423732:LBCZ RS04275
gene id: 1423732:LBCZ_RS04275
uniprot id: S6C9S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

1423732:LBCZ RS11260
gene id: 1423732:LBCZ_RS11260
uniprot id: S6BUL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

1423732:LBCZ RS02780
gene id: 1423732:LBCZ_RS02780
uniprot id: S6C9F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS05400
gene id: 1423732:LBCZ_RS05400
uniprot id: S6CJA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1423732:LBCZ RS06370
gene id: 1423732:LBCZ_RS06370
uniprot id: S6CJE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1423732:LBCZ RS11815
gene id: 1423732:LBCZ_RS11815
uniprot id: S6CK12
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1423732:LBCZ RS10880
gene id: 1423732:LBCZ_RS10880
uniprot id: S6BUG0
names: Caution
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS13405
gene id: 1423732:LBCZ_RS13405
uniprot id: S6BVZ2
names: Similarity
messages: Belongs to the fructosamine kinase family.

1423732:LBCZ RS02605
gene id: 1423732:LBCZ_RS02605
uniprot id: S6C955
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS14055
gene id: 1423732:LBCZ_RS14055
uniprot id: S6C317
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1423732:LBCZ RS13225
gene id: 1423732:LBCZ_RS13225
uniprot id: S6CK66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1423732:LBCZ RS14180
gene id: 1423732:LBCZ_RS14180
uniprot id: S6C336
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRP transporter (TC 2.A.7.5) family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS11875
gene id: 1423732:LBCZ_RS11875
uniprot id: S6CC28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1423732:LBCZ RS00205
gene id: 1423732:LBCZ_RS00205
uniprot id: S6BNP8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS11780
gene id: 1423732:LBCZ_RS11780
uniprot id: S6BUX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1423732:LBCZ RS03625
gene id: 1423732:LBCZ_RS03625
uniprot id: S6BWT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS06540
gene id: 1423732:LBCZ_RS06540
uniprot id: S6C7T1
names: Similarity
messages: Belongs to the DprA/Smf family.

1423732:LBCZ RS01065
gene id: 1423732:LBCZ_RS01065
uniprot id: S6C595
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1423732:LBCZ RS08135
gene id: 1423732:LBCZ_RS08135
uniprot id: S6CJL7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS07255
gene id: 1423732:LBCZ_RS07255
uniprot id: S6BS91
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS07770
gene id: 1423732:LBCZ_RS07770
uniprot id: S6CAK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1423732:LBCZ RS12690
gene id: 1423732:LBCZ_RS12690
uniprot id: S6CK45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS07815
gene id: 1423732:LBCZ_RS07815
uniprot id: S6BZ26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1423732:LBCZ RS08930
gene id: 1423732:LBCZ_RS08930
uniprot id: S6CB05
names: Function
messages: Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase.

1423732:LBCZ RS06625
gene id: 1423732:LBCZ_RS06625
uniprot id: S6BYE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS10280
gene id: 1423732:LBCZ_RS10280
uniprot id: S6C0Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1423732:LBCZ RS11685
gene id: 1423732:LBCZ_RS11685
uniprot id: S6CC01
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS08225
gene id: 1423732:LBCZ_RS08225
uniprot id: S6CAV1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1423732:LBCZ RS12700
gene id: 1423732:LBCZ_RS12700
uniprot id: S6BVD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L-fucose isomerase family.
messages: Converts the aldose L-fucose into the corresponding ketose L-fuculose.
messages: Cytoplasm

1423732:LBCZ RS11630
gene id: 1423732:LBCZ_RS11630
uniprot id: S6C1R6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1423732:LBCZ RS07580
gene id: 1423732:LBCZ_RS07580
uniprot id: S6C882
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1423732:LBCZ RS00310
gene id: 1423732:LBCZ_RS00310
uniprot id: S6C4Z8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1423732:LBCZ RS10495
gene id: 1423732:LBCZ_RS10495
uniprot id: S6C9Y9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1423732:LBCZ RS11745
gene id: 1423732:LBCZ_RS11745
uniprot id: S6CK09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1423732:LBCZ RS04160
gene id: 1423732:LBCZ_RS04160
uniprot id: S6BQP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1423732:LBCZ RS11915
gene id: 1423732:LBCZ_RS11915
uniprot id: S6C1X6
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1423732:LBCZ RS08940
gene id: 1423732:LBCZ_RS08940
uniprot id: S6BT65
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS06475
gene id: 1423732:LBCZ_RS06475
uniprot id: S6BYB6
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1423732:LBCZ RS05955
gene id: 1423732:LBCZ_RS05955
uniprot id: S6C7I7
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1423732:LBCZ RS05840
gene id: 1423732:LBCZ_RS05840
uniprot id: S6CA17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1423732:LBCZ RS07535
gene id: 1423732:LBCZ_RS07535
uniprot id: S6C879
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS08560
gene id: 1423732:LBCZ_RS08560
uniprot id: S6BT07
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1423732:LBCZ RS10870
gene id: 1423732:LBCZ_RS10870
uniprot id: S6C1A2
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1423732:LBCZ RS02105
gene id: 1423732:LBCZ_RS02105
uniprot id: S6BPN3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1423732:LBCZ RS02080
gene id: 1423732:LBCZ_RS02080
uniprot id: S6BPM8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS09815
gene id: 1423732:LBCZ_RS09815
uniprot id: S6C9F5
names: Similarity
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

1423732:LBCZ RS06360
gene id: 1423732:LBCZ_RS06360
uniprot id: S6BRV7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS04925
gene id: 1423732:LBCZ_RS04925
uniprot id: S6BR50
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1423732:LBCZ RS09600
gene id: 1423732:LBCZ_RS09600
uniprot id: S6CB75
names: Similarity
messages: Belongs to the glycosyl hydrolase.

1423732:LBCZ RS05240
gene id: 1423732:LBCZ_RS05240
uniprot id: S6CJA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS06535
gene id: 1423732:LBCZ_RS06535
uniprot id: S6BRY5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1423732:LBCZ RS11740
gene id: 1423732:LBCZ_RS11740
uniprot id: S6CA92
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1423732:LBCZ RS07680
gene id: 1423732:LBCZ_RS07680
uniprot id: S6C886
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1423732:LBCZ RS10245
gene id: 1423732:LBCZ_RS10245
uniprot id: S6BTW1
names: Similarity
messages: Belongs to the EamA transporter family.

1423732:LBCZ RS00925
gene id: 1423732:LBCZ_RS00925
uniprot id: S6C581
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS09930
gene id: 1423732:LBCZ_RS09930
uniprot id: S6C0S4
names: Similarity
messages: Belongs to the TPP enzyme family.

1423732:LBCZ RS01105
gene id: 1423732:LBCZ_RS01105
uniprot id: S6C8K2
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1423732:LBCZ RS07420
gene id: 1423732:LBCZ_RS07420
uniprot id: S6BYU8
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1423732:LBCZ RS09800
gene id: 1423732:LBCZ_RS09800
uniprot id: S6C0Q9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1423732:LBCZ RS12845
gene id: 1423732:LBCZ_RS12845
uniprot id: S6C2G7
names: Subcellular Location Annotation
messages: Membrane

1423732:LBCZ RS06665
gene id: 1423732:LBCZ_RS06665
uniprot id: S6BYF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1423732:LBCZ RS12205
gene id: 1423732:LBCZ_RS12205
uniprot id: S6CC64
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423732:LBCZ RS01680
gene id: 1423732:LBCZ_RS01680
uniprot id: S6CIX2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1423732:LBCZ RS06200
gene id: 1423732:LBCZ_RS06200
uniprot id: S6CJE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1423732:LBCZ RS00170
gene id: 1423732:LBCZ_RS00170
uniprot id: S6BV68
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1423732:LBCZ RS00175
gene id: 1423732:LBCZ_RS00175
uniprot id: S6C899
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1423732:LBCZ RS00550
gene id: 1423732:LBCZ_RS00550
uniprot id: S6C519
names: Similarity
messages: Belongs to the UPF0045 family.

1423732:LBCZ RS12805
gene id: 1423732:LBCZ_RS12805
uniprot id: S6BVF4
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1423732:LBCZ RS00685
gene id: 1423732:LBCZ_RS00685
uniprot id: S6BVC7
names: Similarity
messages: Belongs to the asp23 family.

1423732:LBCZ RS09235
gene id: 1423732:LBCZ_RS09235
uniprot id: S6C9A2
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1423732:LBCZ RS10210
gene id: 1423732:LBCZ_RS10210
uniprot id: S6C0W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS08450
gene id: 1423732:LBCZ_RS08450
uniprot id: S6C024
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1423732:LBCZ RS10135
gene id: 1423732:LBCZ_RS10135
uniprot id: S6C0V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1423732:LBCZ RS08065
gene id: 1423732:LBCZ_RS08065
uniprot id: S6BZW8
names: Similarity
messages: Belongs to the LOG family.

1423732:LBCZ RS12215
gene id: 1423732:LBCZ_RS12215
uniprot id: S6CAF2
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

1423732:LBCZ RS11195
gene id: 1423732:LBCZ_RS11195
uniprot id: S6CA51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1423732:LBCZ RS06270
gene id: 1423732:LBCZ_RS06270
uniprot id: S6CJE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UPF0213 family.
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1423732:LBCZ RS00025
gene id: 1423732:LBCZ_RS00025
uniprot id: S6BNI8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1423732:LBCZ RS04375
gene id: 1423732:LBCZ_RS04375
uniprot id: S6BX41
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1423732:LBCZ RS13560
gene id: 1423732:LBCZ_RS13560
uniprot id: S6CK80
names: Similarity
messages: Belongs to the transposase 7 family.

1423732:LBCZ RS12455
gene id: 1423732:LBCZ_RS12455
uniprot id: S6CK35
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1423732:LBCZ RS06920
gene id: 1423732:LBCZ_RS06920
uniprot id: S6CA99
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1423732:LBCZ RS08155
gene id: 1423732:LBCZ_RS08155
uniprot id: S6CJL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1423732:LBCZ RS13010
gene id: 1423732:LBCZ_RS13010
uniprot id: S6BVJ1
names: Similarity
messages: Belongs to the asp23 family.

1423732:LBCZ RS05460
gene id: 1423732:LBCZ_RS05460
uniprot id: S6C9Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1423732:LBCZ RS07595
gene id: 1423732:LBCZ_RS07595
uniprot id: S6CAH9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1423732:LBCZ RS04355
gene id: 1423732:LBCZ_RS04355
uniprot id: S6BQT0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1423732:LBCZ RS11690
gene id: 1423732:LBCZ_RS11690
uniprot id: S6BUV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.