1415580:GLCE
gene id: 1415580:GLCE
uniprot id: A0A6P7X6A2
names: Similarity
messages: Belongs to the D-glucuronyl C5-epimerase family.

1415580:LOC115456987
gene id: 1415580:LOC115456987
uniprot id: A0A6P7WWI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

1415580:SLC18A3
gene id: 1415580:SLC18A3
uniprot id: A0A6P7Y6Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Vesicular transporter family.
messages: Membrane

1415580:UBN1
gene id: 1415580:UBN1
uniprot id: A0A6P7YS23
uniprot id: A0A6P7YSV1
names: Similarity
messages: Belongs to the ubinuclein family.

1415580:DDX46
gene id: 1415580:DDX46
uniprot id: A0A6P7YXM8
names: Subcellular Location Annotation
messages: Cytoplasm

1415580:SLCO4C1
gene id: 1415580:SLCO4C1
uniprot id: A0A6P7XF51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

1415580:MMP17
gene id: 1415580:MMP17
uniprot id: A0A6P7ZFB2
names: Similarity
messages: Belongs to the peptidase M10A family.

1415580:LOC115462004
gene id: 1415580:LOC115462004
uniprot id: A0A6P7X3F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

1415580:LOC115466510
gene id: 1415580:LOC115466510
uniprot id: A0A6P7XSJ9
uniprot id: A0A6P7XT78
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

1415580:OCM2
gene id: 1415580:OCM2
uniprot id: A0A6P7YU04
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

1415580:LOC115480614
gene id: 1415580:LOC115480614
uniprot id: A0A6P7Z7F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

1415580:FGF3
gene id: 1415580:FGF3
uniprot id: A0A6P7XQD7
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

1415580:MED11
gene id: 1415580:MED11
uniprot id: A0A6P7WUG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 11 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1415580:ADPRH
gene id: 1415580:ADPRH
uniprot id: A0A6P7YPG7
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

1415580:TACC2
gene id: 1415580:TACC2
uniprot id: A0A6P7XSP8
uniprot id: A0A6P7Y011
uniprot id: A0A6P7Y5R1
uniprot id: A0A6P7Y6S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

1415580:ABLIM3
gene id: 1415580:ABLIM3
uniprot id: A0A6P7YWG1
names: Subcellular Location Annotation
messages: Cytoplasm

1415580:CHRDL1
gene id: 1415580:CHRDL1
uniprot id: A0A6P7YR36
names: Subcellular Location Annotation
messages: Secreted

1415580:NDUFS8
gene id: 1415580:NDUFS8
uniprot id: A0A6P7WMD6
uniprot id: A0A6P7WU99
names: Similarity
messages: Belongs to the complex I 23 kDa subunit family.

1415580:B3GALT2
gene id: 1415580:B3GALT2
uniprot id: A0A6P7Y9C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

1415580:MECP2
gene id: 1415580:MECP2
uniprot id: A0A6P7XBH6
names: Subcellular Location Annotation
messages: Nucleus

1415580:KHDC4
gene id: 1415580:KHDC4
uniprot id: A0A6P7WL91
uniprot id: A0A6P7WUJ6
names: Similarity
messages: Belongs to the KHDC4 family.

1415580:INPP5B
gene id: 1415580:INPP5B
uniprot id: A0A6P7Z3W8
uniprot id: A0A6P7Z3X2
uniprot id: A0A6P7Z8Z3
uniprot id: A0A6P7ZBT1
uniprot id: A0A6P7ZEH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: phagosome membrane

1415580:BAG6
gene id: 1415580:BAG6
uniprot id: A0A6P7XCB2
uniprot id: A0A6P7XJ33
uniprot id: A0A6P7XL18
uniprot id: A0A6P7XL25
uniprot id: A0A6P7XRB3
names: Subcellular Location Annotation
messages: Nucleus
messages: extracellular exosome

1415580:LOC115480416
gene id: 1415580:LOC115480416
uniprot id: A0A6P7ZEP8
names: Function
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
messages: Innate immunity protein that plays several important functions in antimicrobial and antitumor defense systems.

1415580:THBS1
gene id: 1415580:THBS1
uniprot id: A0A6P7YS30
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115457835
gene id: 1415580:LOC115457835
uniprot id: A0A6P7WJ64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the APH-1 family.
messages: Component of the gamma-secretase complex.
messages: Membrane
messages: Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors.

1415580:MTERF2
gene id: 1415580:MTERF2
uniprot id: A0A6P7Z0W9
names: Similarity
messages: Belongs to the mTERF family.

1415580:LOC115466575
gene id: 1415580:LOC115466575
uniprot id: A0A6P7XKQ5
names: Similarity
messages: Belongs to the PPP1R15 family.

1415580:MEP1A
gene id: 1415580:MEP1A
uniprot id: A0A6P7XKZ6
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:CHST1
gene id: 1415580:CHST1
uniprot id: A0A6P7XY18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

1415580:PTPRT
gene id: 1415580:PTPRT
uniprot id: A0A6P7YX82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Membrane

1415580:LOC115481674
gene id: 1415580:LOC115481674
uniprot id: A0A6P7ZPS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

1415580:MYOD1
gene id: 1415580:MYOD1
uniprot id: A0A6P7XY41
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

1415580:GPX3
gene id: 1415580:GPX3
uniprot id: A0A6P7YII0
uniprot id: A0A6P7YQL5
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1415580:SLC25A16
gene id: 1415580:SLC25A16
uniprot id: A0A6P7XZB7
uniprot id: A0A6P7YD03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1415580:LOC115474997
gene id: 1415580:LOC115474997
uniprot id: A0A6P7YNJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Cytoplasm
messages: Nucleus
messages: Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.

1415580:LOC115479946
gene id: 1415580:LOC115479946
uniprot id: A0A6P7ZEW3
names: Similarity
messages: Belongs to the MDM20/NAA25 family.

1415580:TRAF4
gene id: 1415580:TRAF4
uniprot id: A0A6P7WUT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

1415580:SFRP1
gene id: 1415580:SFRP1
uniprot id: A0A6P7XXJ6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

1415580:LOC115458178
gene id: 1415580:LOC115458178
uniprot id: A0A6P7WKM8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:IPO9
gene id: 1415580:IPO9
uniprot id: A0A6P7ZAY0
names: Subcellular Location Annotation
messages: Cytoplasm

1415580:LOC115476692
gene id: 1415580:LOC115476692
uniprot id: A0A6P7YP59
uniprot id: A0A6P7YWW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIG1 family.
messages: Membrane

1415580:LOC115457367
gene id: 1415580:LOC115457367
uniprot id: A0A6P7WXJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115460036
gene id: 1415580:LOC115460036
uniprot id: A0A6P7WRE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Secreted

1415580:SLC16A8
gene id: 1415580:SLC16A8
uniprot id: A0A6P7WXM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

1415580:ADGRF5
gene id: 1415580:ADGRF5
uniprot id: A0A6P7XCN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

1415580:SLC25A34
gene id: 1415580:SLC25A34
uniprot id: A0A6P7ZGP9
uniprot id: A0A6P7ZWA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1415580:GOLT1A
gene id: 1415580:GOLT1A
uniprot id: A0A6P7ZJK9
uniprot id: A0A6P7ZWC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

1415580:LOC115460222
gene id: 1415580:LOC115460222
uniprot id: A0A6P7X6V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

1415580:TMCO1
gene id: 1415580:TMCO1
uniprot id: A0A6P7YDN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMCO1 family.
messages: Calcium-selective channel required to prevent calcium stores from overfilling.
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:MAP1LC3A
gene id: 1415580:MAP1LC3A
uniprot id: A0A6P7YJ54
names: Similarity
messages: Belongs to the ATG8 family.

1415580:FER
gene id: 1415580:FER
uniprot id: A0A6P7XGD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.
messages: cytoskeleton

1415580:LOC115457422
gene id: 1415580:LOC115457422
uniprot id: A0A6P7WNR5
names: Subcellular Location Annotation
messages: Membrane

1415580:MARK3
gene id: 1415580:MARK3
uniprot id: A0A6P7YYJ7
uniprot id: A0A6P7Z2N1
uniprot id: A0A6P7Z3G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

1415580:LOC115458334
gene id: 1415580:LOC115458334
uniprot id: A0A6P7X1S8
names: Similarity
messages: Belongs to the NXPE family.

1415580:LOC115469405
gene id: 1415580:LOC115469405
uniprot id: A0A6P7XR67
names: Similarity
messages: Belongs to the PHYHIP family.

1415580:PLG
gene id: 1415580:PLG
uniprot id: A0A6P7XMZ2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Converted into plasmin by plasminogen activators, both plasminogen and its activator being bound to fibrin.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells.
messages: Secreted

1415580:CNNM2
gene id: 1415580:CNNM2
uniprot id: A0A6P7Y6H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Membrane

1415580:ETV1
gene id: 1415580:ETV1
uniprot id: A0A6P7XP53
uniprot id: A0A6P7XX74
uniprot id: A0A6P7Y2P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

1415580:BRINP2
gene id: 1415580:BRINP2
uniprot id: A0A6P7YBF9
names: Similarity
messages: Belongs to the BRINP family.

1415580:LOC115467360
gene id: 1415580:LOC115467360
uniprot id: A0A6P7XPM4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1415580:CLP1
gene id: 1415580:CLP1
uniprot id: A0A6P7WLW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Clp1 family. Clp1 subfamily.
messages: Component of the tRNA splicing endonuclease complex. Component of pre-mRNA cleavage complex II (CF-II).
messages: Nucleus
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; this phosphorylation event is a prerequisite for the subsequent ligation of the two exon halves and the production of a mature tRNA. Component of the pre-mRNA cleavage complex II (CF-II), which seems to be required for mRNA 3'-end formation. Also phosphorylates the 5'-terminus of exogenously introduced short interfering RNAs (siRNAs), which is a necessary prerequisite for their incorporation into the RNA-induced silencing complex (RISC). However, endogenous siRNAs and microRNAs (miRNAs) that are produced by the cleavage of dsRNA precursors by DICER1 already contain a 5'-phosphate group, so this protein may be dispensible for normal RNA-mediated gene silencing.

1415580:LOC115482644
gene id: 1415580:LOC115482644
uniprot id: A0A6P7ZNL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft.
messages: Nucleus

1415580:LOC115461021
gene id: 1415580:LOC115461021
uniprot id: A0A6P7WTA1
uniprot id: A0A6P7X1N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

1415580:OLFML2A
gene id: 1415580:OLFML2A
uniprot id: A0A6P7YJI9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:UXT
gene id: 1415580:UXT
uniprot id: A0A6P7X2G0
names: Similarity
messages: Belongs to the UXT family.

1415580:FAM234B
gene id: 1415580:FAM234B
uniprot id: A0A6P7Y7G0
names: Similarity
messages: Belongs to the FAM234 family.

1415580:SOGA1
gene id: 1415580:SOGA1
uniprot id: A0A6P7YIY9
uniprot id: A0A6P7YR27
names: Similarity
messages: Belongs to the SOGA family.

1415580:ACY1
gene id: 1415580:ACY1
uniprot id: A0A6P7YF59
uniprot id: A0A6P7YFT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family.
messages: Cytoplasm

1415580:GPR158
gene id: 1415580:GPR158
uniprot id: A0A6P7Y2E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115476782
gene id: 1415580:LOC115476782
uniprot id: A0A6P7Z0E4
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

1415580:SCAMP5
gene id: 1415580:SCAMP5
uniprot id: A0A6P7WX44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

1415580:JAKMIP3
gene id: 1415580:JAKMIP3
uniprot id: A0A6P7XTQ7
uniprot id: A0A6P7XTR1
uniprot id: A0A6P7Y154
uniprot id: A0A6P7Y160
uniprot id: A0A6P7Y1Y6
uniprot id: A0A6P7Y1Z1
uniprot id: A0A6P7Y6T9
uniprot id: A0A6P7Y7W8
uniprot id: A0A6P7Y7X2
names: Similarity
messages: Belongs to the JAKMIP family.

1415580:HOXA7
gene id: 1415580:HOXA7
uniprot id: A0A6P7XZG9
uniprot id: A0A6P7XZH4
uniprot id: A0A6P7Y6A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

1415580:GPR65
gene id: 1415580:GPR65
uniprot id: A0A6P7Z4N9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:MYOC
gene id: 1415580:MYOC
uniprot id: A0A6P7Y4V1
uniprot id: A0A6P7YC97
names: Caution
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion intermembrane space
messages: Mitochondrion outer membrane
messages: Rough endoplasmic reticulum
messages: cilium
messages: extracellular exosome
messages: extracellular space

1415580:LOC115481940
gene id: 1415580:LOC115481940
uniprot id: A0A6P7ZVM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Secreted

1415580:GPX2
gene id: 1415580:GPX2
uniprot id: A0A6P7YTX3
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1415580:FAM3A
gene id: 1415580:FAM3A
uniprot id: A0A6P7X3E1
uniprot id: A0A6P7XIJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

1415580:SSBP1
gene id: 1415580:SSBP1
uniprot id: A0A6P7Z6X1
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

1415580:STX11
gene id: 1415580:STX11
uniprot id: A0A6P7XA02
names: Similarity
messages: Belongs to the syntaxin family.

1415580:TSR2
gene id: 1415580:TSR2
uniprot id: A0A6P7X9Z0
names: Function
names: Similarity
messages: Belongs to the TSR2 family.
messages: May be involved in 20S pre-rRNA processing.

1415580:LOC115464667
gene id: 1415580:LOC115464667
uniprot id: A0A6P7XKQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:TRIM46
gene id: 1415580:TRIM46
uniprot id: A0A6P7WQZ9
names: Subcellular Location Annotation
messages: cytoskeleton

1415580:TNFSF15
gene id: 1415580:TNFSF15
uniprot id: A0A6P7Y581
names: Similarity
messages: Belongs to the tumor necrosis factor family.

1415580:PPA1
gene id: 1415580:PPA1
uniprot id: A0A6P7XV81
uniprot id: A0A6P7Y2J4
names: Similarity
messages: Belongs to the PPase family.

1415580:SYCP2
gene id: 1415580:SYCP2
uniprot id: A0A6P7Z0N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYCP2 family.
messages: Nucleus

1415580:PKIB
gene id: 1415580:PKIB
uniprot id: A0A6P7XFZ5
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

1415580:OLFML3
gene id: 1415580:OLFML3
uniprot id: A0A6P7ZDB6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OLFML3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

1415580:SLC45A1
gene id: 1415580:SLC45A1
uniprot id: A0A6P7WF38
uniprot id: A0A6P7WLA2
uniprot id: A0A6P7WN82
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115461320
gene id: 1415580:LOC115461320
uniprot id: A0A6P7X0K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115466370
gene id: 1415580:LOC115466370
uniprot id: A0A6P7XJP8
names: Similarity
messages: Belongs to the cytochrome P450 family.

1415580:LOC115457121
gene id: 1415580:LOC115457121
uniprot id: A0A6P7WVX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:HSD17B10
gene id: 1415580:HSD17B10
uniprot id: A0A6P7X3F9
uniprot id: A0A6P7X9Y1
uniprot id: A0A6P7XC70
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1415580:CCNC
gene id: 1415580:CCNC
uniprot id: A0A6P7XX30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin C subfamily.
messages: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex.
messages: Nucleus

1415580:STT3B
gene id: 1415580:STT3B
uniprot id: A0A6P7Y9W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

1415580:ARPC1A
gene id: 1415580:ARPC1A
uniprot id: A0A6P7YHI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: Nucleus
messages: cytoskeleton

1415580:LOC115457259
gene id: 1415580:LOC115457259
uniprot id: A0A6P7WH08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:EMC4
gene id: 1415580:EMC4
uniprot id: A0A6P7WP89
uniprot id: A0A6P7WWA9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC4 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:PIGO
gene id: 1415580:PIGO
uniprot id: A0A6P7XDJ9
uniprot id: A0A6P7XER3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:RAD23A
gene id: 1415580:RAD23A
uniprot id: A0A6P7XBA8
uniprot id: A0A6P7XQC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

1415580:ARHGEF2
gene id: 1415580:ARHGEF2
uniprot id: A0A6P7WI18
uniprot id: A0A6P7WPC6
uniprot id: A0A6P7WXE3
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Golgi apparatus
messages: Vesicle
messages: spindle
messages: tight junction

1415580:CRH
gene id: 1415580:CRH
uniprot id: A0A6P7X0J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

1415580:LOC115475428
gene id: 1415580:LOC115475428
uniprot id: A0A6P7YUR3
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1415580:NECAP1
gene id: 1415580:NECAP1
uniprot id: A0A6P7WPV6
uniprot id: A0A6P7WXY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

1415580:ARHGEF1
gene id: 1415580:ARHGEF1
uniprot id: A0A6P7YNL2
uniprot id: A0A6P7YV83
uniprot id: A0A6P7YV88
uniprot id: A0A6P7YWD1
uniprot id: A0A6P7YZI6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane

1415580:LOC115460564
gene id: 1415580:LOC115460564
uniprot id: A0A6P7X6H8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:TNFSF11
gene id: 1415580:TNFSF11
uniprot id: A0A6P7XM37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane
messages: Secreted

1415580:PAX1
gene id: 1415580:PAX1
uniprot id: A0A6P7XDD3
names: Subcellular Location Annotation
messages: Nucleus

1415580:ZDHHC13
gene id: 1415580:ZDHHC13
uniprot id: A0A6P7XMK1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

1415580:LAPTM4B
gene id: 1415580:LAPTM4B
uniprot id: A0A6P7X0M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAPTM4/LAPTM5 transporter family.
messages: Cell membrane
messages: Endomembrane system
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane
messages: multivesicular body lumen
messages: multivesicular body membrane

1415580:RPL19
gene id: 1415580:RPL19
uniprot id: A0A6P7ZU95
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Component of the large ribosomal subunit.

1415580:LOC115480179
gene id: 1415580:LOC115480179
uniprot id: A0A6P7ZAD7
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.

1415580:LOXL3
gene id: 1415580:LOXL3
uniprot id: A0A6P7X021
uniprot id: A0A6P7X9F3
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Contains 1 lysine tyrosylquinone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

1415580:PPARGC1B
gene id: 1415580:PPARGC1B
uniprot id: A0A6P7YWY9
names: Subcellular Location Annotation
messages: Nucleus

1415580:AP3M2
gene id: 1415580:AP3M2
uniprot id: A0A6P7XJ27
uniprot id: A0A6P7XSL3
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

1415580:MMP19
gene id: 1415580:MMP19
uniprot id: A0A6P7XH90
names: Similarity
messages: Belongs to the peptidase M10A family.

1415580:LOC115478633
gene id: 1415580:LOC115478633
uniprot id: A0A6P7Z981
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1415580:LOC115464558
gene id: 1415580:LOC115464558
uniprot id: A0A6P7XKG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:GCDH
gene id: 1415580:GCDH
uniprot id: A0A6P7XQC9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1415580:LOC115458211
gene id: 1415580:LOC115458211
uniprot id: A0A6P7WRX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:DOCK9
gene id: 1415580:DOCK9
uniprot id: A0A6P7Y2Z0
names: Similarity
messages: Belongs to the DOCK family.

1415580:LOC115458343
gene id: 1415580:LOC115458343
uniprot id: A0A6P7WLB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

1415580:ZDHHC23
gene id: 1415580:ZDHHC23
uniprot id: A0A6P7Y7D8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

1415580:IGF2BP3
gene id: 1415580:IGF2BP3
uniprot id: A0A6P7XYN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM IMP/VICKZ family.
messages: Cytoplasm
messages: Nucleus

1415580:LOC115476463
gene id: 1415580:LOC115476463
uniprot id: A0A6P7YZL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

1415580:NOL12
gene id: 1415580:NOL12
uniprot id: A0A6P7Y8L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP17 family.
messages: nucleolus

1415580:LOC115464377
gene id: 1415580:LOC115464377
uniprot id: A0A6P7XDL5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:SOD3
gene id: 1415580:SOD3
uniprot id: A0A6P7WVA6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1415580:KDM1B
gene id: 1415580:KDM1B
uniprot id: A0A6P7YRD7
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

1415580:DNASE1L1
gene id: 1415580:DNASE1L1
uniprot id: A0A6P7X339
names: Similarity
messages: Belongs to the DNase I family.

1415580:LOC115472051
gene id: 1415580:LOC115472051
uniprot id: A0A6P7YA78
names: Similarity
messages: Belongs to the cytochrome P450 family.

1415580:LOC115479933
gene id: 1415580:LOC115479933
uniprot id: A0A6P7Z485
uniprot id: A0A6P7ZC47
uniprot id: A0A6P7ZFD3
names: Similarity
messages: Belongs to the cytochrome P450 family.

1415580:UBALD2
gene id: 1415580:UBALD2
uniprot id: A0A6P7YGK6
names: Similarity
messages: Belongs to the UBALD family.

1415580:C3H6orf120
gene id: 1415580:C3H6orf120
uniprot id: A0A6P7XJL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0669 family.
messages: Secreted

1415580:HYLS1
gene id: 1415580:HYLS1
uniprot id: A0A6P7YLI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HYLS1 family.
messages: centriole
messages: cilium

1415580:SPTY2D1
gene id: 1415580:SPTY2D1
uniprot id: A0A6P7XVG7
names: Similarity
messages: Belongs to the SPT2 family.

1415580:FAM155B
gene id: 1415580:FAM155B
uniprot id: A0A6P7YQ35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NALF family.
messages: Membrane

1415580:MBTD1
gene id: 1415580:MBTD1
uniprot id: A0A6P7Y5B8
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115469316
gene id: 1415580:LOC115469316
uniprot id: A0A6P7XQL7
uniprot id: A0A6P7XYM8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:ADGB
gene id: 1415580:ADGB
uniprot id: A0A6P7XT91
names: Caution
names: Similarity
messages: Belongs to the peptidase C2 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115458255
gene id: 1415580:LOC115458255
uniprot id: A0A6P7WKW0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:SEC23B
gene id: 1415580:SEC23B
uniprot id: A0A6P7XN78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

1415580:MRPL34
gene id: 1415580:MRPL34
uniprot id: A0A6P7Z5Z6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1415580:LOC115481995
gene id: 1415580:LOC115481995
uniprot id: A0A6P7ZVS2
names: Similarity
messages: Belongs to the CFAP97 family.

1415580:FAM120A
gene id: 1415580:FAM120A
uniprot id: A0A6P7YMJ1
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

1415580:LOC115457149
gene id: 1415580:LOC115457149
uniprot id: A0A6P7WGQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

1415580:LOC115474531
gene id: 1415580:LOC115474531
uniprot id: A0A6P7YRU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

1415580:LOC115464510
gene id: 1415580:LOC115464510
uniprot id: A0A6P7XBS1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LOC115461140
gene id: 1415580:LOC115461140
uniprot id: A0A6P7X906
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:PSMG2
gene id: 1415580:PSMG2
uniprot id: A0A6P7YLK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PSMG2 family.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1.
messages: Forms a heterodimer with PSMG1.

1415580:MYOZ3
gene id: 1415580:MYOZ3
uniprot id: A0A6P7YZ43
names: Similarity
messages: Belongs to the myozenin family.

1415580:LOC115482006
gene id: 1415580:LOC115482006
uniprot id: A0A6P7ZT58
names: Subcellular Location Annotation
messages: Membrane

1415580:TMBIM6
gene id: 1415580:TMBIM6
uniprot id: A0A6P7XPU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1415580:ANXA6
gene id: 1415580:ANXA6
uniprot id: A0A6P7YY52
uniprot id: A0A6P7Z1W6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: May associate with CD21. May regulate the release of Ca(2+) from intracellular stores.
messages: Melanosome

1415580:HK3
gene id: 1415580:HK3
uniprot id: A0A6P7YKJ8
uniprot id: A0A6P7YTJ2
names: Similarity
messages: Belongs to the hexokinase family.

1415580:MSI1
gene id: 1415580:MSI1
uniprot id: A0A6P7Z8L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Musashi family.
messages: Cytoplasm

1415580:GRPEL1
gene id: 1415580:GRPEL1
uniprot id: A0A6P7X8Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

1415580:LOC115477313
gene id: 1415580:LOC115477313
uniprot id: A0A6P7YZM2
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1415580:UMPS
gene id: 1415580:UMPS
uniprot id: A0A6P7YKC9
names: Similarity
messages: In the C-terminal section; belongs to the OMP decarboxylase family.
messages: In the N-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1415580:LOC115461345
gene id: 1415580:LOC115461345
uniprot id: A0A6P7X3B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115481047
gene id: 1415580:LOC115481047
uniprot id: A0A6P7Z995
names: Similarity
messages: Belongs to the dapper family.

1415580:LOC115480539
gene id: 1415580:LOC115480539
uniprot id: A0A6P7ZJ34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: synaptosome

1415580:ZC3H14
gene id: 1415580:ZC3H14
uniprot id: A0A6P7YXE9
uniprot id: A0A6P7YYJ9
uniprot id: A0A6P7Z1F3
uniprot id: A0A6P7Z2C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZC3H14 family.
messages: Involved in poly(A) tail length control in neuronal cells. Binds the polyadenosine RNA oligonucleotides.
messages: Nucleus speckle

1415580:LOC115461214
gene id: 1415580:LOC115461214
uniprot id: A0A6P7WUB1
names: Similarity
messages: Belongs to the nanos family.

1415580:LOC115457497
gene id: 1415580:LOC115457497
uniprot id: A0A6P7WY04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

1415580:LOC115481010
gene id: 1415580:LOC115481010
uniprot id: A0A6P7ZIL5
names: Similarity
messages: Belongs to the peptidase C2 family.

1415580:LOC115468457
gene id: 1415580:LOC115468457
uniprot id: A0A6P7XU62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1415580:CUEDC2
gene id: 1415580:CUEDC2
uniprot id: A0A6P7Y9C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUEDC2 family.
messages: Cytoplasm
messages: Nucleus

1415580:TRAPPC6B
gene id: 1415580:TRAPPC6B
uniprot id: A0A6P7Z0T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: cis-Golgi network

1415580:LOC115457206
gene id: 1415580:LOC115457206
uniprot id: A0A6P7WN62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:TNS4
gene id: 1415580:TNS4
uniprot id: A0A6P7ZD79
uniprot id: A0A6P7ZHS9
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

1415580:UBE2A
gene id: 1415580:UBE2A
uniprot id: A0A6P7YR96
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

1415580:LOC115456696
gene id: 1415580:LOC115456696
uniprot id: A0A6P7WF48
uniprot id: A0A6P7WLB2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

1415580:LOC115461921
gene id: 1415580:LOC115461921
uniprot id: A0A6P7X371
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Photoreceptor outer segment membrane

1415580:GHITM
gene id: 1415580:GHITM
uniprot id: A0A6P7Y8L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1415580:BOD1
gene id: 1415580:BOD1
uniprot id: A0A6P7YJK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BOD1 family.
messages: centrosome
messages: kinetochore

1415580:PPM1B
gene id: 1415580:PPM1B
uniprot id: A0A6P7XEM9
uniprot id: A0A6P7XLW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

1415580:FAM168B
gene id: 1415580:FAM168B
uniprot id: A0A6P7Z062
uniprot id: A0A6P7Z5L3
uniprot id: A0A6P7Z7Z3
names: Similarity
messages: Belongs to the FAM168 family.

1415580:TJP1
gene id: 1415580:TJP1
uniprot id: A0A6P7X2B0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: tight junction

1415580:LOC115464668
gene id: 1415580:LOC115464668
uniprot id: A0A6P7XJU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:KIAA2013
gene id: 1415580:KIAA2013
uniprot id: A0A6P7ZVG2
uniprot id: A0A6P7ZW04
uniprot id: A0A6P7ZY04
names: Subcellular Location Annotation
messages: Membrane

1415580:TACC1
gene id: 1415580:TACC1
uniprot id: A0A6P7XYW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

1415580:PNOC
gene id: 1415580:PNOC
uniprot id: A0A6P7XDW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Secreted

1415580:LOC115469055
gene id: 1415580:LOC115469055
uniprot id: A0A6P7XXC6
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

1415580:MAN2A1
gene id: 1415580:MAN2A1
uniprot id: A0A6P7XA08
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

1415580:LOC115457234
gene id: 1415580:LOC115457234
uniprot id: A0A6P7WW87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

1415580:CPXM2
gene id: 1415580:CPXM2
uniprot id: A0A6P7Y6Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

1415580:PRKCQ
gene id: 1415580:PRKCQ
uniprot id: A0A6P7YXS8
uniprot id: A0A6P7Z3I4
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

1415580:LOC115476198
gene id: 1415580:LOC115476198
uniprot id: A0A6P7YXV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

1415580:LOC115480574
gene id: 1415580:LOC115480574
uniprot id: A0A6P7ZC25
uniprot id: A0A6P7ZLH8
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

1415580:LOC115482273
gene id: 1415580:LOC115482273
uniprot id: A0A6P7ZVN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Cell membrane
messages: Enhances Ca(2+)-mediated inhibition of inositol 1,4,5-triphosphate receptor (ITPR) Ca(2+) release.
messages: Membrane
messages: Nucleus outer membrane

1415580:LOC115481828
gene id: 1415580:LOC115481828
uniprot id: A0A6P7ZGQ0
uniprot id: A0A6P7ZUK4
names: Similarity
messages: Belongs to the intermediate filament family.

1415580:PTPRZ1
gene id: 1415580:PTPRZ1
uniprot id: A0A6P7Z0U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.
messages: Membrane

1415580:LOC115473094
gene id: 1415580:LOC115473094
uniprot id: A0A6P7YF98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Membrane

1415580:PSMB3
gene id: 1415580:PSMB3
uniprot id: A0A6P7ZCH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

1415580:LOC115474239
gene id: 1415580:LOC115474239
uniprot id: A0A6P7YQS4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Hydrolase highly specific for thiamine triphosphate (ThTP).
messages: Monomer.

1415580:YIPF2
gene id: 1415580:YIPF2
uniprot id: A0A6P7XI49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

1415580:TMSB15B
gene id: 1415580:TMSB15B
uniprot id: A0A6P7YJX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

1415580:PHB2
gene id: 1415580:PHB2
uniprot id: A0A6P7WJA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

1415580:KCTD10
gene id: 1415580:KCTD10
uniprot id: A0A6P7ZC13
uniprot id: A0A6P7ZFA9
names: Similarity
messages: Belongs to the BACURD family.

1415580:LOC115465211
gene id: 1415580:LOC115465211
uniprot id: A0A6P7XG74
uniprot id: A0A6P7XM87
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115479000
gene id: 1415580:LOC115479000
uniprot id: A0A6P7ZAX4
names: Similarity
messages: Belongs to the peptidase M14 family.

1415580:LOC115466922
gene id: 1415580:LOC115466922
uniprot id: A0A6P7XUM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: Membrane
messages: Vacuole membrane

1415580:PRDM1
gene id: 1415580:PRDM1
uniprot id: A0A6P7X7H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Interacts with PRMT5. Interacts with FBXO10. Interacts with FBXO11.
messages: Nucleus
messages: Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection. Binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells. Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions.

1415580:LOC115468325
gene id: 1415580:LOC115468325
uniprot id: A0A6P7XTJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:CPB2
gene id: 1415580:CPB2
uniprot id: A0A6P7XTL9
names: Similarity
messages: Belongs to the peptidase M14 family.

1415580:NKD1
gene id: 1415580:NKD1
uniprot id: A0A6P7XXR7
uniprot id: A0A6P7Y5B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKD family.
messages: Cell autonomous antagonist of the canonical Wnt signaling pathway.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

1415580:LOC115467246
gene id: 1415580:LOC115467246
uniprot id: A0A6P7XW37
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

1415580:TENT5B
gene id: 1415580:TENT5B
uniprot id: A0A6P7Z8L1
names: Similarity
messages: Belongs to the TENT family.

1415580:CACNG2
gene id: 1415580:CACNG2
uniprot id: A0A6P7ZMW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

1415580:LOC115458196
gene id: 1415580:LOC115458196
uniprot id: A0A6P7X055
names: Subcellular Location Annotation
messages: Membrane

1415580:BACE1
gene id: 1415580:BACE1
uniprot id: A0A6P7ZG22
uniprot id: A0A6P7ZTB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Membrane
messages: Membrane raft
messages: Recycling endosome
messages: trans-Golgi network

1415580:POLRMT
gene id: 1415580:POLRMT
uniprot id: A0A6P7ZF77
uniprot id: A0A6P7ZFR1
names: Function
names: Similarity
messages: Belongs to the phage and mitochondrial RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

1415580:APOA5
gene id: 1415580:APOA5
uniprot id: A0A6P7ZVR8
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

1415580:PRR15L
gene id: 1415580:PRR15L
uniprot id: A0A6P7ZUN0
names: Similarity
messages: Belongs to the PRR15 family.

1415580:LOC115459926
gene id: 1415580:LOC115459926
uniprot id: A0A6P7WWV7
uniprot id: A0A6P7X4Y0
uniprot id: A0A6P7X655
names: Similarity
messages: Belongs to the Fmt family.

1415580:PUS1
gene id: 1415580:PUS1
uniprot id: A0A6P7Z212
uniprot id: A0A6P7Z7E1
uniprot id: A0A6P7ZCM7
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

1415580:LOC115457118
gene id: 1415580:LOC115457118
uniprot id: A0A6P7WGM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:POLR3A
gene id: 1415580:POLR3A
uniprot id: A0A6P7XUF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

1415580:LOC115482012
gene id: 1415580:LOC115482012
uniprot id: A0A6P7ZDH2
names: Similarity
messages: Belongs to the peptidase A1 family.

1415580:LOC115479264
gene id: 1415580:LOC115479264
uniprot id: A0A6P7Z657
uniprot id: A0A6P7ZBD4
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

1415580:CHAC1
gene id: 1415580:CHAC1
uniprot id: A0A6P7YVS0
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

1415580:LOC115477271
gene id: 1415580:LOC115477271
uniprot id: A0A6P7YQA6
names: Similarity
messages: Belongs to the actin family.

1415580:TFRC
gene id: 1415580:TFRC
uniprot id: A0A6P7Z931
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Acts as a lipid sensor that regulates mitochondrial fusion by regulating activation of the JNK pathway.
messages: Homodimer; disulfide-linked.
messages: Melanosome
messages: Membrane
messages: Stearoylated.

1415580:LOC115473809
gene id: 1415580:LOC115473809
uniprot id: A0A6P7YBB8
names: Similarity
messages: Belongs to the SCAR/WAVE family.

1415580:LOC115464567
gene id: 1415580:LOC115464567
uniprot id: A0A6P7X5B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:TXNRD1
gene id: 1415580:TXNRD1
uniprot id: A0A6P7Z507
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1415580:NSG1
gene id: 1415580:NSG1
uniprot id: A0A6P7X905
names: Similarity
messages: Belongs to the NSG family.

1415580:EXOC6B
gene id: 1415580:EXOC6B
uniprot id: A0A6P7WUK1
uniprot id: A0A6P7X0C2
uniprot id: A0A6P7X8B9
uniprot id: A0A6P7X8C3
uniprot id: A0A6P7X9P3
names: Function
names: Similarity
messages: Belongs to the SEC15 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

1415580:TBR1
gene id: 1415580:TBR1
uniprot id: A0A6P7YLZ5
uniprot id: A0A6P7YS09
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

1415580:MRPL18
gene id: 1415580:MRPL18
uniprot id: A0A6P7X6I2
uniprot id: A0A6P7X7L2
names: Similarity
messages: Belongs to the universal ribosomal protein uL18 family.

1415580:LOC115457464
gene id: 1415580:LOC115457464
uniprot id: A0A6P7WXU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

1415580:LOC115472429
gene id: 1415580:LOC115472429
uniprot id: A0A6P7YHR7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1415580:PRPS1
gene id: 1415580:PRPS1
uniprot id: A0A6P7YJU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.

1415580:WLS
gene id: 1415580:WLS
uniprot id: A0A6P7Y9J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the wntless family.
messages: Golgi apparatus membrane
messages: Membrane

1415580:NHSL2
gene id: 1415580:NHSL2
uniprot id: A0A6P7YL62
names: Similarity
messages: Belongs to the NHS family.

1415580:KIF13A
gene id: 1415580:KIF13A
uniprot id: A0A6P7YIG5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

1415580:NEMP2
gene id: 1415580:NEMP2
uniprot id: A0A6P7YP96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NEMP family.
messages: Nucleus inner membrane

1415580:DYNC1H1
gene id: 1415580:DYNC1H1
uniprot id: A0A6P7YXP9
names: Similarity
messages: Belongs to the dynein heavy chain family.

1415580:LOC115463686
gene id: 1415580:LOC115463686
uniprot id: A0A6P7XCL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 32 family.
messages: Golgi apparatus membrane

1415580:SNAP23
gene id: 1415580:SNAP23
uniprot id: A0A6P7Z4B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: synaptosome

1415580:LOC115481662
gene id: 1415580:LOC115481662
uniprot id: A0A6P7ZG36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
messages: Membrane
messages: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

1415580:LOC115457298
gene id: 1415580:LOC115457298
uniprot id: A0A6P7WNE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:NINJ1
gene id: 1415580:NINJ1
uniprot id: A0A6P7YA86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ninjurin family.
messages: Membrane

1415580:STAMBPL1
gene id: 1415580:STAMBPL1
uniprot id: A0A6P7XTZ2
uniprot id: A0A6P7Y1F0
names: Similarity
messages: Belongs to the peptidase M67C family.

1415580:GDF11
gene id: 1415580:GDF11
uniprot id: A0A6P7XB66
names: Similarity
messages: Belongs to the TGF-beta family.

1415580:GALNT10
gene id: 1415580:GALNT10
uniprot id: A0A6P7YPD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

1415580:EDNRB
gene id: 1415580:EDNRB
uniprot id: A0A6P7Y097
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:CACNG6
gene id: 1415580:CACNG6
uniprot id: A0A6P7XKC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2.
messages: Membrane
messages: Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
messages: sarcolemma

1415580:SUCNR1
gene id: 1415580:SUCNR1
uniprot id: A0A6P7YZI2
uniprot id: A0A6P7Z536
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:ITGB2
gene id: 1415580:ITGB2
uniprot id: A0A6P7YI97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

1415580:ITGA9
gene id: 1415580:ITGA9
uniprot id: A0A6P7Y967
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

1415580:ADGRB3
gene id: 1415580:ADGRB3
uniprot id: A0A6P7XH92
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115464658
gene id: 1415580:LOC115464658
uniprot id: A0A6P7XKP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:EXTL3
gene id: 1415580:EXTL3
uniprot id: A0A6P7XPU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

1415580:LOC115474756
gene id: 1415580:LOC115474756
uniprot id: A0A6P7YNE3
uniprot id: A0A6P7YNE6
names: Similarity
messages: Belongs to the PHF5 family.

1415580:TRNT1
gene id: 1415580:TRNT1
uniprot id: A0A6P7Y2F0
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1415580:CTBP2
gene id: 1415580:CTBP2
uniprot id: A0A6P7Y6G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

1415580:ITIH5
gene id: 1415580:ITIH5
uniprot id: A0A6P7Z7A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

1415580:LOC115477153
gene id: 1415580:LOC115477153
uniprot id: A0A6P7Z2H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1415580:KMT5A
gene id: 1415580:KMT5A
uniprot id: A0A6P7ZMR5
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

1415580:LOC115474686
gene id: 1415580:LOC115474686
uniprot id: A0A6P7YSC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

1415580:HS3ST2
gene id: 1415580:HS3ST2
uniprot id: A0A6P7YUY1
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

1415580:POLR3K
gene id: 1415580:POLR3K
uniprot id: A0A6P7YUJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

1415580:SLC35F4
gene id: 1415580:SLC35F4
uniprot id: A0A6P7YTL9
uniprot id: A0A6P7Z1A8
uniprot id: A0A6P7Z4U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

1415580:LOC115469003
gene id: 1415580:LOC115469003
uniprot id: A0A6P7XX79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Cytoplasm
messages: Nucleus
messages: Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.

1415580:TOP1MT
gene id: 1415580:TOP1MT
uniprot id: A0A6P7ZLW6
uniprot id: A0A6P7ZLY4
uniprot id: A0A6P7ZM03
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1415580:LOC115472295
gene id: 1415580:LOC115472295
uniprot id: A0A6P7YBT5
names: Similarity
messages: Belongs to the janus family.

1415580:GRIN3A
gene id: 1415580:GRIN3A
uniprot id: A0A6P7XIR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

1415580:FOXP2
gene id: 1415580:FOXP2
uniprot id: A0A6P7YWZ4
uniprot id: A0A6P7Z2S0
uniprot id: A0A6P7Z4T0
names: Subcellular Location Annotation
messages: Nucleus

1415580:SFT2D3
gene id: 1415580:SFT2D3
uniprot id: A0A6P7Z4T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

1415580:SYBU
gene id: 1415580:SYBU
uniprot id: A0A6P7Z444
names: Subcellular Location Annotation
messages: Membrane

1415580:DDB1
gene id: 1415580:DDB1
uniprot id: A0A6P7Y1T5
uniprot id: A0A6P7Y2D8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDB1 family.
messages: Component of complexes involved in DNA repair and protein ubiquitination. May play a role in the regulation of the circadian clock.
messages: Component of the UV-DDB complex.
messages: Nucleus
messages: The core of the protein consists of three WD40 beta-propeller domains.

1415580:DRGX
gene id: 1415580:DRGX
uniprot id: A0A6P7YCM4
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115456693
gene id: 1415580:LOC115456693
uniprot id: A0A6P7WU90
names: Subcellular Location Annotation
messages: Membrane

1415580:FXN
gene id: 1415580:FXN
uniprot id: A0A6P7XGB9
uniprot id: A0A6P7XHG0
names: Similarity
messages: Belongs to the frataxin family.

1415580:LOC115476809
gene id: 1415580:LOC115476809
uniprot id: A0A6P7Z0G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Nucleus

1415580:DBX1
gene id: 1415580:DBX1
uniprot id: A0A6P7XQD1
names: Subcellular Location Annotation
messages: Nucleus

1415580:ARL11
gene id: 1415580:ARL11
uniprot id: A0A6P7XQ89
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

1415580:LOC115457599
gene id: 1415580:LOC115457599
uniprot id: A0A6P7WXE6
uniprot id: A0A6P7WYE0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Secreted

1415580:GTF2F2
gene id: 1415580:GTF2F2
uniprot id: A0A6P7Y056
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB.

1415580:LOC115457270
gene id: 1415580:LOC115457270
uniprot id: A0A6P7WQA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:FLNC
gene id: 1415580:FLNC
uniprot id: A0A6P7ZBF8
names: Similarity
messages: Belongs to the filamin family.

1415580:CACNG3
gene id: 1415580:CACNG3
uniprot id: A0A6P7YMQ8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:SH3RF3
gene id: 1415580:SH3RF3
uniprot id: A0A6P7Y2W4
names: Similarity
messages: Belongs to the SH3RF family.

1415580:GRK2
gene id: 1415580:GRK2
uniprot id: A0A6P7WTW4
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

1415580:PPIC
gene id: 1415580:PPIC
uniprot id: A0A6P7X1H7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1415580:PHACTR4
gene id: 1415580:PHACTR4
uniprot id: A0A6P7Z7L3
uniprot id: A0A6P7ZA71
uniprot id: A0A6P7ZA76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.
messages: Cytoplasm
messages: Regulator of protein phosphatase 1 (PP1) required for neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. Acts as an activator of PP1. During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina. Also acts as a regulator of migration of enteric neural crest cells (ENCCs) by activating PP1, leading to repression of the integrin signaling through the rho/rock pathway.
messages: lamellipodium

1415580:DERL1
gene id: 1415580:DERL1
uniprot id: A0A6P7ZDF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Membrane

1415580:PARD6G
gene id: 1415580:PARD6G
uniprot id: A0A6P7YKG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

1415580:CERS4
gene id: 1415580:CERS4
uniprot id: A0A6P7ZND8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

1415580:MVD
gene id: 1415580:MVD
uniprot id: A0A6P7YBL7
names: Function
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.
messages: Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis.

1415580:THOC2
gene id: 1415580:THOC2
uniprot id: A0A6P7YRA4
uniprot id: A0A6P7YRG5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the THOC2 family.
messages: Component of the THO complex, which is composed of THOC1, THOC2, THOC3, THOC5, THOC6 and THOC7; together with at least ALYREF/THOC4, DDX39B, SARNP/CIP29 and CHTOP, THO forms the transcription/export (TREX) complex which seems to have a dynamic structure involving ATP-dependent remodeling. Interacts with THOC1, POLDIP3 and ZC3H11A.
messages: Nucleus

1415580:ZFYVE9
gene id: 1415580:ZFYVE9
uniprot id: A0A6P7Y3D6
uniprot id: A0A6P7YAR2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Early endosome membrane

1415580:LANCL1
gene id: 1415580:LANCL1
uniprot id: A0A6P7YNV5
names: Similarity
messages: Belongs to the LanC-like protein family.

1415580:GAPDHS
gene id: 1415580:GAPDHS
uniprot id: A0A6P7YUU2
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

1415580:SPIN1
gene id: 1415580:SPIN1
uniprot id: A0A6P7XAE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPIN/STSY family.
messages: Nucleus

1415580:ENGASE
gene id: 1415580:ENGASE
uniprot id: A0A6P7YMS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 85 family.
messages: cytosol

1415580:CACNB3
gene id: 1415580:CACNB3
uniprot id: A0A6P7XAS8
uniprot id: A0A6P7XHL2
uniprot id: A0A6P7XJM6
uniprot id: A0A6P7XPT0
uniprot id: A0A6P7XQL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: Cytoplasm

1415580:RER1
gene id: 1415580:RER1
uniprot id: A0A6P7WMP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
messages: Membrane

1415580:MKNK2
gene id: 1415580:MKNK2
uniprot id: A0A6P7ZHZ4
names: Similarity
messages: Belongs to the protein kinase superfamily.

1415580:LOC115457276
gene id: 1415580:LOC115457276
uniprot id: A0A6P7WWD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:HDDC2
gene id: 1415580:HDDC2
uniprot id: A0A6P7XFP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HDDC2 family.
messages: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
messages: Homodimer.

1415580:LOC115465472
gene id: 1415580:LOC115465472
uniprot id: A0A6P7XH99
uniprot id: A0A6P7XMC8
uniprot id: A0A6P7XN38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

1415580:RPS11
gene id: 1415580:RPS11
uniprot id: A0A6P7XSY3
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

1415580:GPR18
gene id: 1415580:GPR18
uniprot id: A0A6P7XPC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane

1415580:FOXJ3
gene id: 1415580:FOXJ3
uniprot id: A0A6P7WVQ8
names: Subcellular Location Annotation
messages: Nucleus

1415580:KPNA6
gene id: 1415580:KPNA6
uniprot id: A0A6P7ZKX7
names: Similarity
messages: Belongs to the importin alpha family.

1415580:LOC115457187
gene id: 1415580:LOC115457187
uniprot id: A0A6P7WGU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:CPLX4
gene id: 1415580:CPLX4
uniprot id: A0A6P7WXJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

1415580:LOC115462551
gene id: 1415580:LOC115462551
uniprot id: A0A6P7XDZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin 150 kDa subunit family.
messages: cell cortex
messages: cytoskeleton

1415580:LOC115460504
gene id: 1415580:LOC115460504
uniprot id: A0A6P7X7E5
names: Similarity
messages: Belongs to the peptidase M10A family.

1415580:ZDHHC9
gene id: 1415580:ZDHHC9
uniprot id: A0A6P7YR93
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

1415580:LOC115482008
gene id: 1415580:LOC115482008
uniprot id: A0A6P7ZT68
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

1415580:DESI1
gene id: 1415580:DESI1
uniprot id: A0A6P7Z2B3
names: Similarity
messages: Belongs to the DeSI family.

1415580:GADD45G
gene id: 1415580:GADD45G
uniprot id: A0A6P7WY67
names: Similarity
messages: Belongs to the GADD45 family.

1415580:TUBB6
gene id: 1415580:TUBB6
uniprot id: A0A6P7YXJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

1415580:NAV3
gene id: 1415580:NAV3
uniprot id: A0A6P7YRP8
uniprot id: A0A6P7YRQ4
uniprot id: A0A6P7YY73
uniprot id: A0A6P7YY79
uniprot id: A0A6P7Z283
uniprot id: A0A6P7Z347
names: Similarity
messages: Belongs to the Nav/unc-53 family.

1415580:RPL37
gene id: 1415580:RPL37
uniprot id: A0A6P7XJR1
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

1415580:RIN2
gene id: 1415580:RIN2
uniprot id: A0A6P7X916
uniprot id: A0A6P7XFW8
names: Similarity
messages: Belongs to the RIN (Ras interaction/interference) family.

1415580:WNT3A
gene id: 1415580:WNT3A
uniprot id: A0A6P7XR59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

1415580:EIF3H
gene id: 1415580:EIF3H
uniprot id: A0A6P7ZET7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit H family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

1415580:LOC115472284
gene id: 1415580:LOC115472284
uniprot id: A0A6P7YBD9
names: Similarity
messages: Belongs to the protein kinase superfamily.

1415580:SLC6A17
gene id: 1415580:SLC6A17
uniprot id: A0A6P7ZCL8
uniprot id: A0A6P7ZGQ9
uniprot id: A0A6P7ZR93
uniprot id: A0A6P7ZUK7
uniprot id: A0A6P7ZUL0
uniprot id: A0A6P7ZVB2
uniprot id: A0A6P7ZVB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1415580:GUCY1B1
gene id: 1415580:GUCY1B1
uniprot id: A0A6P7WW96
uniprot id: A0A6P7X4T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

1415580:LOC115457128
gene id: 1415580:LOC115457128
uniprot id: A0A6P7WGN4
names: Subcellular Location Annotation
messages: Membrane

1415580:HOXB7
gene id: 1415580:HOXB7
uniprot id: A0A6P7ZQV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

1415580:LOC115471772
gene id: 1415580:LOC115471772
uniprot id: A0A6P7YF44
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115457033
gene id: 1415580:LOC115457033
uniprot id: A0A6P7WML8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:MAP2K3
gene id: 1415580:MAP2K3
uniprot id: A0A6P7YQ96
uniprot id: A0A6P7YUG5
names: Similarity
messages: Belongs to the protein kinase superfamily.

1415580:SHCBP1L
gene id: 1415580:SHCBP1L
uniprot id: A0A6P7YG26
names: Subcellular Location Annotation
messages: spindle

1415580:LOC115463687
gene id: 1415580:LOC115463687
uniprot id: A0A6P7XJ14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 32 family.
messages: Golgi apparatus membrane

1415580:PSENEN
gene id: 1415580:PSENEN
uniprot id: A0A6P7YX12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEN-2 family.
messages: Golgi stack membrane
messages: Membrane

1415580:LOC115460551
gene id: 1415580:LOC115460551
uniprot id: A0A6P7X7J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic cobalamin transport proteins family.
messages: Secreted

1415580:MRPL13
gene id: 1415580:MRPL13
uniprot id: A0A6P7ZGD0
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

1415580:CORO6
gene id: 1415580:CORO6
uniprot id: A0A6P7WFF2
uniprot id: A0A6P7WLJ9
uniprot id: A0A6P7WNH0
names: Similarity
messages: Belongs to the WD repeat coronin family.

1415580:LOC115475608
gene id: 1415580:LOC115475608
uniprot id: A0A6P7YVJ8
names: Similarity
messages: Belongs to the thioesterase PaaI family.

1415580:EFNA1
gene id: 1415580:EFNA1
uniprot id: A0A6P7WZ53
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:DUSP27
gene id: 1415580:DUSP27
uniprot id: A0A6P7XWL1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

1415580:SETD6
gene id: 1415580:SETD6
uniprot id: A0A6P7XVI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily.
messages: Nucleus
messages: Protein-lysine N-methyltransferase.

1415580:LOC115464332
gene id: 1415580:LOC115464332
uniprot id: A0A6P7XIT8
names: Similarity
messages: Belongs to the MHC class I family.

1415580:PHKG2
gene id: 1415580:PHKG2
uniprot id: A0A6P7YLL5
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily.
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.

1415580:ANAPC10
gene id: 1415580:ANAPC10
uniprot id: A0A6P7X2E4
uniprot id: A0A6P7X4Z7
names: Function
names: Similarity
messages: Belongs to the APC10 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.

1415580:BBS5
gene id: 1415580:BBS5
uniprot id: A0A6P7YG00
uniprot id: A0A6P7YNM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBS5 family.
messages: Membrane
messages: Required for ciliogenesis.
messages: centriolar satellite
messages: cilium membrane

1415580:GABRA3
gene id: 1415580:GABRA3
uniprot id: A0A6P7YTL1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

1415580:ITIH2
gene id: 1415580:ITIH2
uniprot id: A0A6P7Z390
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

1415580:ARRDC4
gene id: 1415580:ARRDC4
uniprot id: A0A6P7X7X3
names: Similarity
messages: Belongs to the arrestin family.

1415580:LOC115482497
gene id: 1415580:LOC115482497
uniprot id: A0A6P7ZFQ3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1415580:LOC115462257
gene id: 1415580:LOC115462257
uniprot id: A0A6P7WY03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

1415580:LOC115464492
gene id: 1415580:LOC115464492
uniprot id: A0A6P7XBQ2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:PIGG
gene id: 1415580:PIGG
uniprot id: A0A6P7XAJ9
uniprot id: A0A6P7XI47
uniprot id: A0A6P7XJ76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGG subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:SETD3
gene id: 1415580:SETD3
uniprot id: A0A6P7Z295
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. SETD3 actin-histidine methyltransferase family.
messages: Cytoplasm

1415580:LOC115480247
gene id: 1415580:LOC115480247
uniprot id: A0A6P7ZGD6
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

1415580:FOXO3
gene id: 1415580:FOXO3
uniprot id: A0A6P7XWG3
names: Subcellular Location Annotation
messages: Nucleus

1415580:EMC8
gene id: 1415580:EMC8
uniprot id: A0A6P7XYC3
names: Similarity
messages: Belongs to the EMC8/EMC9 family.

1415580:LOC115461218
gene id: 1415580:LOC115461218
uniprot id: A0A6P7WUC5
names: Similarity
messages: Belongs to the PDCD4 family.

1415580:LOC115466286
gene id: 1415580:LOC115466286
uniprot id: A0A6P7XLB7
uniprot id: A0A6P7XSC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPACA4/bouncer family.
messages: Cell membrane
messages: Membrane

1415580:SDHAF1
gene id: 1415580:SDHAF1
uniprot id: A0A6P7X9D4
names: Similarity
messages: Belongs to the complex I LYR family. SDHAF1 subfamily.

1415580:LOC115460500
gene id: 1415580:LOC115460500
uniprot id: A0A6P7X0W5
names: Similarity
messages: Belongs to the VPS28 family.

1415580:BCL2L1
gene id: 1415580:BCL2L1
uniprot id: A0A6P7WVN4
uniprot id: A0A6P7YW82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane
messages: Mitochondrion matrix
messages: Nucleus membrane
messages: centrosome
messages: cytosol
messages: synaptic vesicle membrane

1415580:LOC115462641
gene id: 1415580:LOC115462641
uniprot id: A0A6P7X7S7
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

1415580:SORCS1
gene id: 1415580:SORCS1
uniprot id: A0A6P7Y6I5
names: Similarity
messages: Belongs to the VPS10-related sortilin family. SORCS subfamily.

1415580:TSNAX
gene id: 1415580:TSNAX
uniprot id: A0A6P7XR98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the translin family.
messages: Nucleus

1415580:TLR2
gene id: 1415580:TLR2
uniprot id: A0A6P7WXX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

1415580:MAB21L2
gene id: 1415580:MAB21L2
uniprot id: A0A6P7X4X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mab-21 family.
messages: Cytoplasm
messages: Nucleus

1415580:IPO11
gene id: 1415580:IPO11
uniprot id: A0A6P7X6W4
uniprot id: A0A6P7XFM5
names: Subcellular Location Annotation
messages: Cytoplasm

1415580:POU3F1
gene id: 1415580:POU3F1
uniprot id: A0A6P7ZN87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

1415580:LOC115482026
gene id: 1415580:LOC115482026
uniprot id: A0A6P7ZVW0
names: Subcellular Location Annotation
messages: Cytoplasm

1415580:MRPL12
gene id: 1415580:MRPL12
uniprot id: A0A6P7YAN1
uniprot id: A0A6P7YHN2
uniprot id: A0A6P7YHW0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL12 family.

1415580:MPV17L2
gene id: 1415580:MPV17L2
uniprot id: A0A6P7ZBZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

1415580:LPCAT1
gene id: 1415580:LPCAT1
uniprot id: A0A6P7YL25
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

1415580:LOC115460508
gene id: 1415580:LOC115460508
uniprot id: A0A6P7X7F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:PRPF19
gene id: 1415580:PRPF19
uniprot id: A0A6P7ZVZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PRP19 family.
messages: Homotetramer.
messages: Lipid droplet
messages: Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.
messages: nucleoplasm

1415580:GPRC5B
gene id: 1415580:GPRC5B
uniprot id: A0A6P7YP82
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:CXCL12
gene id: 1415580:CXCL12
uniprot id: A0A6P7Y1R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

1415580:MCM8
gene id: 1415580:MCM8
uniprot id: A0A6P7XP69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

1415580:LOC115466840
gene id: 1415580:LOC115466840
uniprot id: A0A6P7XUA0
names: Subcellular Location Annotation
messages: Nucleus

1415580:C6H17orf80
gene id: 1415580:C6H17orf80
uniprot id: A0A6P7YA99
names: Function
names: Similarity
messages: Belongs to the ATPase F chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.

1415580:LOC115471353
gene id: 1415580:LOC115471353
uniprot id: A0A6P7XZV8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
messages: Homodimer; disulfide-linked.
messages: Membrane

1415580:RBL2
gene id: 1415580:RBL2
uniprot id: A0A6P7Y5G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

1415580:WNT2B
gene id: 1415580:WNT2B
uniprot id: A0A6P7ZE41
uniprot id: A0A6P7ZUL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

1415580:LOC115468185
gene id: 1415580:LOC115468185
uniprot id: A0A6P7XSU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:HSF2
gene id: 1415580:HSF2
uniprot id: A0A6P7XFX6
uniprot id: A0A6P7XUT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

1415580:BCL7C
gene id: 1415580:BCL7C
uniprot id: A0A6P7YSP9
names: Similarity
messages: Belongs to the BCL7 family.

1415580:CDX4
gene id: 1415580:CDX4
uniprot id: A0A6P7YDY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

1415580:HSPB8
gene id: 1415580:HSPB8
uniprot id: A0A6P7ZKS3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1415580:ATF1
gene id: 1415580:ATF1
uniprot id: A0A6P7XNJ5
uniprot id: A0A6P7XTY6
uniprot id: A0A6P7XUJ0
names: Subcellular Location Annotation
messages: Nucleus

1415580:MMS19
gene id: 1415580:MMS19
uniprot id: A0A6P7Y6K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MET18/MMS19 family.
messages: Component of the CIA complex.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.
messages: Nucleus
messages: spindle

1415580:NAB1
gene id: 1415580:NAB1
uniprot id: A0A6P7YC02
uniprot id: A0A6P7YJE7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAB family.
messages: Homomultimers may associate with EGR1 bound to DNA.
messages: Nucleus

1415580:LOC115466361
gene id: 1415580:LOC115466361
uniprot id: A0A6P7XJP2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:SPTBN2
gene id: 1415580:SPTBN2
uniprot id: A0A6P7Z2R7
names: Similarity
messages: Belongs to the spectrin family.

1415580:JUND
gene id: 1415580:JUND
uniprot id: A0A6P7ZA96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

1415580:LOC115469724
gene id: 1415580:LOC115469724
uniprot id: A0A6P7XSH4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115472308
gene id: 1415580:LOC115472308
uniprot id: A0A6P7YHM1
names: Subcellular Location Annotation
messages: Synapse

1415580:HSP90AA1
gene id: 1415580:HSP90AA1
uniprot id: A0A6P7YYU9
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1415580:CEP63
gene id: 1415580:CEP63
uniprot id: A0A6P7Z695
uniprot id: A0A6P7Z8S5
uniprot id: A0A6P7ZBG2
names: Similarity
messages: Belongs to the CEP63 family.

1415580:UBE4B
gene id: 1415580:UBE4B
uniprot id: A0A6P7ZMY5
uniprot id: A0A6P7ZWQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

1415580:LOC115481818
gene id: 1415580:LOC115481818
uniprot id: A0A6P7ZVA3
names: Similarity
messages: Belongs to the MS4A family.

1415580:ARHGAP32
gene id: 1415580:ARHGAP32
uniprot id: A0A6P7ZCI1
uniprot id: A0A6P7ZGM2
names: Similarity
messages: Belongs to the PX domain-containing GAP family.

1415580:LOC115470874
gene id: 1415580:LOC115470874
uniprot id: A0A6P7Y5V3
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.

1415580:FRRS1
gene id: 1415580:FRRS1
uniprot id: A0A6P7Y1I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRRS1 family.
messages: Membrane

1415580:AACS
gene id: 1415580:AACS
uniprot id: A0A6P7ZC35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Converts acetoacetate to acetoacetyl-CoA in the cytosol.
messages: cytosol

1415580:GNPDA1
gene id: 1415580:GNPDA1
uniprot id: A0A6P7YWT4
uniprot id: A0A6P7YX16
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

1415580:ARFGEF3
gene id: 1415580:ARFGEF3
uniprot id: A0A6P7XV80
names: Subcellular Location Annotation
messages: perinuclear region

1415580:MRS2
gene id: 1415580:MRS2
uniprot id: A0A6P7X0C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mitochondrion inner membrane

1415580:LOC115462571
gene id: 1415580:LOC115462571
uniprot id: A0A6P7XE08
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115460635
gene id: 1415580:LOC115460635
uniprot id: A0A6P7WYP1
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

1415580:ERG
gene id: 1415580:ERG
uniprot id: A0A6P7XYU3
uniprot id: A0A6P7Y4R0
uniprot id: A0A6P7Y5Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

1415580:WNT5B
gene id: 1415580:WNT5B
uniprot id: A0A6P7Z465
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

1415580:ADPRHL2
gene id: 1415580:ADPRHL2
uniprot id: A0A6P7ZGF9
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

1415580:YME1L1
gene id: 1415580:YME1L1
uniprot id: A0A6P7XRL4
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

1415580:MAP6
gene id: 1415580:MAP6
uniprot id: A0A6P7XI72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STOP family.
messages: cytoskeleton

1415580:LOC115482058
gene id: 1415580:LOC115482058
uniprot id: A0A6P7ZV66
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115467820
gene id: 1415580:LOC115467820
uniprot id: A0A6P7XRP5
uniprot id: A0A6P7XXI1
names: Subcellular Location Annotation
messages: Cytoplasm

1415580:LOC115458091
gene id: 1415580:LOC115458091
uniprot id: A0A6P7WRH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115472887
gene id: 1415580:LOC115472887
uniprot id: A0A6P7Y6U3
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

1415580:FMR1
gene id: 1415580:FMR1
uniprot id: A0A6P7YJY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMR1 family.
messages: Cell membrane
messages: Cytoplasmic ribonucleoprotein granule
messages: Membrane
messages: Perikaryon
messages: Presynaptic cell membrane
messages: Synaptic cell membrane
messages: axon
messages: centromere
messages: dendrite
messages: dendritic spine
messages: filopodium tip
messages: growth cone
messages: neuron projection
messages: nucleolus
messages: perinuclear region
messages: synaptosome

1415580:ELF4
gene id: 1415580:ELF4
uniprot id: A0A6P7YG91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

1415580:ASXL3
gene id: 1415580:ASXL3
uniprot id: A0A6P7Z301
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Asx family.
messages: Nucleus

1415580:BTC
gene id: 1415580:BTC
uniprot id: A0A6P7X3P0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115457281
gene id: 1415580:LOC115457281
uniprot id: A0A6P7WQB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LHX2
gene id: 1415580:LHX2
uniprot id: A0A6P7YGK9
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115475893
gene id: 1415580:LOC115475893
uniprot id: A0A6P7YWR4
names: Similarity
messages: Belongs to the actin family.

1415580:MRAP2
gene id: 1415580:MRAP2
uniprot id: A0A6P7XGA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRAP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:DPT
gene id: 1415580:DPT
uniprot id: A0A6P7XW99
names: Similarity
messages: Belongs to the dermatopontin family.

1415580:MED16
gene id: 1415580:MED16
uniprot id: A0A6P7Z692
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 16 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1415580:LOC115471290
gene id: 1415580:LOC115471290
uniprot id: A0A6P7XZQ3
names: Similarity
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.

1415580:LOC115471915
gene id: 1415580:LOC115471915
uniprot id: A0A6P7YF56
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

1415580:PEMT
gene id: 1415580:PEMT
uniprot id: A0A6P7YZ07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
messages: Catalyzes the three sequential steps of the methylation pathway for the biosynthesis of phosphatidylcholine, a critical and essential component for membrane structure. Uses S-adenosylmethionine (S-adenosyl-L-methionine, SAM or AdoMet) as the methyl group donor for the methylation of phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE) to phosphatidylmonomethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine, PMME), PMME to phosphatidyldimethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine, PDME), and PDME to phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine, PC), producing S-adenosyl-L-homocysteine in each step.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

1415580:BTG4
gene id: 1415580:BTG4
uniprot id: A0A6P7ZFI6
names: Similarity
messages: Belongs to the BTG family.

1415580:LOC115467815
gene id: 1415580:LOC115467815
uniprot id: A0A6P7XPT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:SNU13
gene id: 1415580:SNU13
uniprot id: A0A6P7Y7X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

1415580:YAE1
gene id: 1415580:YAE1
uniprot id: A0A6P7XGG5
uniprot id: A0A6P7XHK7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

1415580:TOMM40L
gene id: 1415580:TOMM40L
uniprot id: A0A6P7WRC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

1415580:PRODH2
gene id: 1415580:PRODH2
uniprot id: A0A6P7YLC4
uniprot id: A0A6P7YQT0
names: Function
names: Similarity
messages: Belongs to the proline oxidase family.
messages: Converts proline to delta-1-pyrroline-5-carboxylate.

1415580:LMF1
gene id: 1415580:LMF1
uniprot id: A0A6P7YW94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase maturation factor family.
messages: Endoplasmic reticulum membrane
messages: Involved in the maturation of specific proteins in the endoplasmic reticulum.
messages: Membrane

1415580:UIMC1
gene id: 1415580:UIMC1
uniprot id: A0A6P7YJG2
uniprot id: A0A6P7YS88
uniprot id: A0A6P7YWC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAP80 family.
messages: Nucleus

1415580:LOC115464640
gene id: 1415580:LOC115464640
uniprot id: A0A6P7X5I2
names: Similarity
messages: Belongs to the helicase family.

1415580:MACO1
gene id: 1415580:MACO1
uniprot id: A0A6P7ZC94
uniprot id: A0A6P7ZD04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the macoilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane
messages: Rough endoplasmic reticulum membrane

1415580:LOC115472318
gene id: 1415580:LOC115472318
uniprot id: A0A6P7YH94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:SLC17A6
gene id: 1415580:SLC17A6
uniprot id: A0A6P7XXY2
names: Subcellular Location Annotation
messages: Membrane

1415580:EDC3
gene id: 1415580:EDC3
uniprot id: A0A6P7WVR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EDC3 family.
messages: P-body

1415580:PAX9
gene id: 1415580:PAX9
uniprot id: A0A6P7YSX8
uniprot id: A0A6P7YZB9
uniprot id: A0A6P7Z3H4
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115457103
gene id: 1415580:LOC115457103
uniprot id: A0A6P7WGL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115463050
gene id: 1415580:LOC115463050
uniprot id: A0A6P7X725
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1415580:RPS16
gene id: 1415580:RPS16
uniprot id: A0A6P7YUY0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1415580:ARF1
gene id: 1415580:ARF1
uniprot id: A0A6P7XC62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

1415580:CDKAL1
gene id: 1415580:CDKAL1
uniprot id: A0A6P7YIT6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
messages: Endoplasmic reticulum membrane

1415580:RAB4A
gene id: 1415580:RAB4A
uniprot id: A0A6P7XNX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport.

1415580:GALNT18
gene id: 1415580:GALNT18
uniprot id: A0A6P7XNA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

1415580:ATP2B1
gene id: 1415580:ATP2B1
uniprot id: A0A6P7YWC5
uniprot id: A0A6P7Z459
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:LOC115468207
gene id: 1415580:LOC115468207
uniprot id: A0A6P7XYR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:PTER
gene id: 1415580:PTER
uniprot id: A0A6P7XJ13
uniprot id: A0A6P7XYE4
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:RPL39
gene id: 1415580:RPL39
uniprot id: A0A6P7YME2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

1415580:GDI2
gene id: 1415580:GDI2
uniprot id: A0A6P7Z8C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

1415580:ANO5
gene id: 1415580:ANO5
uniprot id: A0A6P7XMI4
uniprot id: A0A6P7XUA6
uniprot id: A0A6P7XVN3
uniprot id: A0A6P7Y0K1
uniprot id: A0A6P7Y161
uniprot id: A0A6P7Y165
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

1415580:PEX14
gene id: 1415580:PEX14
uniprot id: A0A6P7ZG53
uniprot id: A0A6P8A066
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-14 family.
messages: Component of the peroxisomal translocation machinery.
messages: Peroxisome membrane

1415580:VAT1
gene id: 1415580:VAT1
uniprot id: A0A6P7ZQB2
uniprot id: A0A6P7ZV15
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1415580:KCNJ2
gene id: 1415580:KCNJ2
uniprot id: A0A6P7YA84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ2 subfamily.
messages: Membrane

1415580:SLC2A12
gene id: 1415580:SLC2A12
uniprot id: A0A6P7XFK6
uniprot id: A0A6P7XP55
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

1415580:PLXNA4
gene id: 1415580:PLXNA4
uniprot id: A0A6P7Z7F3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:MPP7
gene id: 1415580:MPP7
uniprot id: A0A6P7XRK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: adherens junction
messages: tight junction

1415580:LOC115476750
gene id: 1415580:LOC115476750
uniprot id: A0A6P7YXB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:KATNB1
gene id: 1415580:KATNB1
uniprot id: A0A6P7Y3K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat KATNB1 family.
messages: Cytoplasm
messages: Interacts with KATNA1. This interaction enhances the microtubule binding and severing activity of KATNA1 and also targets this activity to the centrosome.
messages: Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
messages: centrosome
messages: cytoskeleton
messages: spindle
messages: spindle pole

1415580:LOC115457044
gene id: 1415580:LOC115457044
uniprot id: A0A6P7WGG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:CER1
gene id: 1415580:CER1
uniprot id: A0A6P7X3H9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

1415580:SPTBN4
gene id: 1415580:SPTBN4
uniprot id: A0A6P7ZDL1
names: Similarity
messages: Belongs to the spectrin family.

1415580:GALNT4
gene id: 1415580:GALNT4
uniprot id: A0A6P7YCR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

1415580:SLC9A3R1
gene id: 1415580:SLC9A3R1
uniprot id: A0A6P7YM38
uniprot id: A0A6P7YMA7
names: Function
names: Subcellular Location Annotation
messages: Endomembrane system
messages: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.
messages: filopodium
messages: microvillus
messages: ruffle

1415580:CEP19
gene id: 1415580:CEP19
uniprot id: A0A6P7YY65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP19 family.
messages: centriole
messages: cilium basal body
messages: spindle pole

1415580:LOC115473867
gene id: 1415580:LOC115473867
uniprot id: A0A6P7YP84
names: Subcellular Location Annotation
messages: Secreted

1415580:HOOK2
gene id: 1415580:HOOK2
uniprot id: A0A6P7XB54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hook family.
messages: cytoskeleton

1415580:LOC115472698
gene id: 1415580:LOC115472698
uniprot id: A0A6P7YCZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the meteorin family.
messages: Secreted

1415580:PTK2B
gene id: 1415580:PTK2B
uniprot id: A0A6P7XG86
uniprot id: A0A6P7XPR9
uniprot id: A0A6P7XVL1
names: Subcellular Location Annotation
messages: Cell membrane
messages: focal adhesion

1415580:BRINP3
gene id: 1415580:BRINP3
uniprot id: A0A6P7YJV3
names: Similarity
messages: Belongs to the BRINP family.

1415580:RGS2
gene id: 1415580:RGS2
uniprot id: A0A6P7YB96
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: nucleolus

1415580:PUS7L
gene id: 1415580:PUS7L
uniprot id: A0A6P7YXJ9
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

1415580:PLCB1
gene id: 1415580:PLCB1
uniprot id: A0A6P7X9A0
uniprot id: A0A6P7XG59
uniprot id: A0A6P7XIA6
names: Function
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

1415580:ATP5PO
gene id: 1415580:ATP5PO
uniprot id: A0A6P7XXT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

1415580:LOC115466534
gene id: 1415580:LOC115466534
uniprot id: A0A6P7XSP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

1415580:TFB1M
gene id: 1415580:TFB1M
uniprot id: A0A6P7X6Z0
uniprot id: A0A6P7XL22
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

1415580:LOC115473537
gene id: 1415580:LOC115473537
uniprot id: A0A6P7YAE9
uniprot id: A0A6P7YHL7
uniprot id: A0A6P7YMP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

1415580:CDK5
gene id: 1415580:CDK5
uniprot id: A0A6P7XDX0
names: Similarity
messages: Belongs to the protein kinase superfamily.

1415580:LOC115476432
gene id: 1415580:LOC115476432
uniprot id: A0A6P7YUL0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1415580:ODR4
gene id: 1415580:ODR4
uniprot id: A0A6P7Y744
uniprot id: A0A6P7YJU2
names: Function
names: Similarity
messages: Belongs to the ODR-4 family.
messages: May play a role in the trafficking of a subset of G-protein coupled receptors.

1415580:MTO1
gene id: 1415580:MTO1
uniprot id: A0A6P7ZSA7
names: Function
names: Similarity
messages: Belongs to the MnmG family.
messages: Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.

1415580:NOP10
gene id: 1415580:NOP10
uniprot id: A0A6P7Z202
names: Similarity
messages: Belongs to the NOP10 family.

1415580:LOC115460043
gene id: 1415580:LOC115460043
uniprot id: A0A6P7X6I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

1415580:LOC115457854
gene id: 1415580:LOC115457854
uniprot id: A0A6P7WYJ7
names: Caution
names: Similarity
messages: Belongs to the DMBT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115464581
gene id: 1415580:LOC115464581
uniprot id: A0A6P7XC42
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LOC115472558
gene id: 1415580:LOC115472558
uniprot id: A0A6P7YIH0
names: Function
names: Similarity
messages: Belongs to the ATPase d subunit family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.

1415580:LRRC8C
gene id: 1415580:LRRC8C
uniprot id: A0A6P7YFU6
uniprot id: A0A6P7YFV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

1415580:VAMP2
gene id: 1415580:VAMP2
uniprot id: A0A6P7WSY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane
messages: synaptic vesicle membrane

1415580:COL4A5
gene id: 1415580:COL4A5
uniprot id: A0A6P7YPM1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

1415580:LOC115464959
gene id: 1415580:LOC115464959
uniprot id: A0A6P7XLL0
uniprot id: A0A6P7XLL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Nucleus

1415580:LOC115468593
gene id: 1415580:LOC115468593
uniprot id: A0A6P7XUU2
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse
messages: axon
messages: dendrite

1415580:SLIT2
gene id: 1415580:SLIT2
uniprot id: A0A6P7WV97
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

1415580:UCHL1
gene id: 1415580:UCHL1
uniprot id: A0A6P7WZ10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C12 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:TFR2
gene id: 1415580:TFR2
uniprot id: A0A6P7WQW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

1415580:CDK6
gene id: 1415580:CDK6
uniprot id: A0A6P7XLE7
uniprot id: A0A6P7XUP1
names: Similarity
messages: Belongs to the protein kinase superfamily.

1415580:RNF121
gene id: 1415580:RNF121
uniprot id: A0A6P7XTK5
names: Subcellular Location Annotation
messages: Membrane

1415580:CSNK2A2
gene id: 1415580:CSNK2A2
uniprot id: A0A6P7Y8M3
names: Similarity
messages: Belongs to the protein kinase superfamily.

1415580:LOC115475029
gene id: 1415580:LOC115475029
uniprot id: A0A6P7YNM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115457960
gene id: 1415580:LOC115457960
uniprot id: A0A6P7WJP9
uniprot id: A0A6P7WT16
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:SV2B
gene id: 1415580:SV2B
uniprot id: A0A6P7WT15
uniprot id: A0A6P7X1F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

1415580:SPCS1
gene id: 1415580:SPCS1
uniprot id: A0A6P7YKC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:DSEL
gene id: 1415580:DSEL
uniprot id: A0A6P7YYC9
names: Similarity
messages: Belongs to the dermatan-sulfate isomerase family.

1415580:LOC115465336
gene id: 1415580:LOC115465336
uniprot id: A0A6P7XEH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

1415580:WNT11
gene id: 1415580:WNT11
uniprot id: A0A6P7XXK2
uniprot id: A0A6P7XXK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

1415580:CENPC
gene id: 1415580:CENPC
uniprot id: A0A6P7X1M6
names: Similarity
messages: Belongs to the CENP-C/MIF2 family.

1415580:LOC115481156
gene id: 1415580:LOC115481156
uniprot id: A0A6P7ZK03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

1415580:COL4A2
gene id: 1415580:COL4A2
uniprot id: A0A6P7XXY6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

1415580:MYADM
gene id: 1415580:MYADM
uniprot id: A0A6P7XM92
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115465007
gene id: 1415580:LOC115465007
uniprot id: A0A6P7XFL0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LOC115475821
gene id: 1415580:LOC115475821
uniprot id: A0A6P7YSL6
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

1415580:RALY
gene id: 1415580:RALY
uniprot id: A0A6P7YTD0
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

1415580:ZDHHC6
gene id: 1415580:ZDHHC6
uniprot id: A0A6P7Y0E5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

1415580:LOC115464434
gene id: 1415580:LOC115464434
uniprot id: A0A6P7XBK1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:RPRD1B
gene id: 1415580:RPRD1B
uniprot id: A0A6P7YSF4
names: Similarity
messages: Belongs to the UPF0400 (RTT103) family.

1415580:LOC115457293
gene id: 1415580:LOC115457293
uniprot id: A0A6P7WND7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115466332
gene id: 1415580:LOC115466332
uniprot id: A0A6P7XRS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Membrane

1415580:ACAP3
gene id: 1415580:ACAP3
uniprot id: A0A6P7ZND9
uniprot id: A0A6P7ZW25
uniprot id: A0A6P8A0E4
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

1415580:TSPAN14
gene id: 1415580:TSPAN14
uniprot id: A0A6P7XUJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

1415580:LOC115462149
gene id: 1415580:LOC115462149
uniprot id: A0A6P7WXS4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:LOC115474513
gene id: 1415580:LOC115474513
uniprot id: A0A6P7YRS0
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

1415580:TSEN34
gene id: 1415580:TSEN34
uniprot id: A0A6P7XKB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.
messages: Nucleus

1415580:FTSJ3
gene id: 1415580:FTSJ3
uniprot id: A0A6P7WLM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
messages: Interacts with NIP7.
messages: Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation.
messages: nucleolus

1415580:AMBP
gene id: 1415580:AMBP
uniprot id: A0A6P7YIM7
names: Similarity
names: Subcellular Location Annotation
messages: In the N-terminal section; belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

1415580:SNX19
gene id: 1415580:SNX19
uniprot id: A0A6P7ZMM9
uniprot id: A0A6P7ZTD5
names: Similarity
messages: Belongs to the sorting nexin family.

1415580:ADAMTS4
gene id: 1415580:ADAMTS4
uniprot id: A0A6P7WLJ7
uniprot id: A0A6P7WSL4
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

1415580:LOC115463510
gene id: 1415580:LOC115463510
uniprot id: A0A6P7X9F5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-delta family.
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

1415580:LOC115468241
gene id: 1415580:LOC115468241
uniprot id: A0A6P7XRC4
names: Subcellular Location Annotation
messages: focal adhesion
messages: lamellipodium
messages: sarcomere

1415580:LOC115478535
gene id: 1415580:LOC115478535
uniprot id: A0A6P7YXF9
uniprot id: A0A6P7Z380
uniprot id: A0A6P7Z5B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

1415580:LARGE2
gene id: 1415580:LARGE2
uniprot id: A0A6P7XUP2
uniprot id: A0A6P7Y1J6
names: Subcellular Location Annotation
messages: Membrane

1415580:ZRANB1
gene id: 1415580:ZRANB1
uniprot id: A0A6P7XZV1
uniprot id: A0A6P7Y6N6
names: Similarity
messages: Belongs to the peptidase C64 family.

1415580:ORAI2
gene id: 1415580:ORAI2
uniprot id: A0A6P7WNF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

1415580:BLK
gene id: 1415580:BLK
uniprot id: A0A6P7XM52
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

1415580:PDGFC
gene id: 1415580:PDGFC
uniprot id: A0A6P7X4S8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

1415580:LOC115466334
gene id: 1415580:LOC115466334
uniprot id: A0A6P7XLI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Membrane

1415580:FBLN1
gene id: 1415580:FBLN1
uniprot id: A0A6P7Z361
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fibulin family.
messages: Homomultimerizes and interacts with various extracellular matrix components.
messages: Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

1415580:VIPAS39
gene id: 1415580:VIPAS39
uniprot id: A0A6P7Z2G5
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome
messages: Late endosome
messages: Vesicle

1415580:PDK1
gene id: 1415580:PDK1
uniprot id: A0A6P7YEX5
uniprot id: A0A6P7YMK5
uniprot id: A0A6P7YS34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

1415580:NDRG1
gene id: 1415580:NDRG1
uniprot id: A0A6P7ZC67
names: Similarity
messages: Belongs to the NDRG family.

1415580:ZHX3
gene id: 1415580:ZHX3
uniprot id: A0A6P7YQ10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

1415580:LOC115456650
gene id: 1415580:LOC115456650
uniprot id: A0A6P7WL48
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1415580:HMGCL
gene id: 1415580:HMGCL
uniprot id: A0A6P7Z3D0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HMG-CoA lyase family.
messages: Homodimer; disulfide-linked. Can also form homotetramers.
messages: Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.

1415580:LOC115462568
gene id: 1415580:LOC115462568
uniprot id: A0A6P7X537
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GnRH family.
messages: Secreted
messages: Stimulates the secretion of gonadotropins.

1415580:ACSL6
gene id: 1415580:ACSL6
uniprot id: A0A6P7YYD9
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

1415580:KDM4A
gene id: 1415580:KDM4A
uniprot id: A0A6P7Y8Q8
names: Similarity
messages: Belongs to the JHDM3 histone demethylase family.

1415580:PPFIA4
gene id: 1415580:PPFIA4
uniprot id: A0A6P7ZFS3
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

1415580:LOC115480934
gene id: 1415580:LOC115480934
uniprot id: A0A6P7ZMM7
names: Subcellular Location Annotation
messages: Cytoplasm

1415580:NIPSNAP1
gene id: 1415580:NIPSNAP1
uniprot id: A0A6P7ZCC2
names: Similarity
messages: Belongs to the NipSnap family.

1415580:ZNRF3
gene id: 1415580:ZNRF3
uniprot id: A0A6P7ZF33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZNRF3 family.
messages: Cell membrane
messages: Membrane

1415580:CROT
gene id: 1415580:CROT
uniprot id: A0A6P7XRF0
uniprot id: A0A6P7XRG4
uniprot id: A0A6P7XT60
uniprot id: A0A6P7XYY7
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

1415580:TFIP11
gene id: 1415580:TFIP11
uniprot id: A0A6P7XMN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFP11/STIP family.
messages: Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events.
messages: Nucleus

1415580:CLDN16
gene id: 1415580:CLDN16
uniprot id: A0A6P7Z8Y4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

1415580:NCL
gene id: 1415580:NCL
uniprot id: A0A6P7Z5S5
uniprot id: A0A6P7Z8F1
uniprot id: A0A6P7Z971
names: Subcellular Location Annotation
messages: nucleolus

1415580:LOC115458095
gene id: 1415580:LOC115458095
uniprot id: A0A6P7WKC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:RRM2B
gene id: 1415580:RRM2B
uniprot id: A0A6P7Z9T1
uniprot id: A0A6P7Z9U1
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

1415580:METTL4
gene id: 1415580:METTL4
uniprot id: A0A6P7WS21
uniprot id: A0A6P7X713
names: Similarity
messages: Belongs to the MT-A70-like family.

1415580:EIF2B1
gene id: 1415580:EIF2B1
uniprot id: A0A6P7ZMA5
uniprot id: A0A6P7ZNY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.
messages: Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
messages: Complex of five different subunits; alpha, beta, gamma, delta and epsilon.

1415580:SDR16C5
gene id: 1415580:SDR16C5
uniprot id: A0A6P7YTJ3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1415580:DYM
gene id: 1415580:DYM
uniprot id: A0A6P7X8H9
names: Similarity
messages: Belongs to the dymeclin family.

1415580:NFX1
gene id: 1415580:NFX1
uniprot id: A0A6P7Y6R6
uniprot id: A0A6P7Y6T2
uniprot id: A0A6P7YCA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NFX1 family.
messages: Nucleus

1415580:MRPL30
gene id: 1415580:MRPL30
uniprot id: A0A6P7Y2N5
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

1415580:LOC115464707
gene id: 1415580:LOC115464707
uniprot id: A0A6P7XKT5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:OXA1L
gene id: 1415580:OXA1L
uniprot id: A0A6P7WRK0
uniprot id: A0A6P7WZV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

1415580:CYFIP2
gene id: 1415580:CYFIP2
uniprot id: A0A6P7YQU9
names: Similarity
messages: Belongs to the CYFIP family.

1415580:LOC115472193
gene id: 1415580:LOC115472193
uniprot id: A0A6P7YB49
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:PPP1CC
gene id: 1415580:PPP1CC
uniprot id: A0A6P7Z540
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: Cleavage furrow
messages: Cytoplasm
messages: Midbody

1415580:CLCN1
gene id: 1415580:CLCN1
uniprot id: A0A6P7WQS7
uniprot id: A0A6P7WYW9
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115480433
gene id: 1415580:LOC115480433
uniprot id: A0A6P7ZER3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:OGG1
gene id: 1415580:OGG1
uniprot id: A0A6P7YG75
uniprot id: A0A6P7YGI2
uniprot id: A0A6P7YLP2
uniprot id: A0A6P7YLV9
names: Similarity
messages: Belongs to the type-1 OGG1 family.

1415580:LOC115462773
gene id: 1415580:LOC115462773
uniprot id: A0A6P7XDD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the APH-1 family.
messages: Component of the gamma-secretase complex.
messages: Membrane
messages: Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors.

1415580:PARL
gene id: 1415580:PARL
uniprot id: A0A6P7Z0X0
uniprot id: A0A6P7Z684
uniprot id: A0A6P7Z8R5
names: Subcellular Location Annotation
messages: Membrane

1415580:TRDMT1
gene id: 1415580:TRDMT1
uniprot id: A0A6P7XSE7
uniprot id: A0A6P7XXJ5
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115466518
gene id: 1415580:LOC115466518
uniprot id: A0A6P7XSQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Secreted

1415580:MDH1B
gene id: 1415580:MDH1B
uniprot id: A0A6P7YR29
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.

1415580:GDF7
gene id: 1415580:GDF7
uniprot id: A0A6P7XLB1
names: Similarity
messages: Belongs to the TGF-beta family.

1415580:GPR34
gene id: 1415580:GPR34
uniprot id: A0A6P7XYM0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:HMGCS2
gene id: 1415580:HMGCS2
uniprot id: A0A6P7Y4U6
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

1415580:CCT8
gene id: 1415580:CCT8
uniprot id: A0A6P7Y5D4
uniprot id: A0A6P7YBE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: cilium basal body

1415580:CD82
gene id: 1415580:CD82
uniprot id: A0A6P7XUM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

1415580:LOC115456992
gene id: 1415580:LOC115456992
uniprot id: A0A6P7WPI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

1415580:LOC115473794
gene id: 1415580:LOC115473794
uniprot id: A0A6P7YAV8
uniprot id: A0A6P7YIA1
uniprot id: A0A6P7YNJ2
uniprot id: A0A6P7YNY2
names: Similarity
messages: Belongs to the angiomotin family.

1415580:VAMP3
gene id: 1415580:VAMP3
uniprot id: A0A6P7ZM59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

1415580:PSMC3IP
gene id: 1415580:PSMC3IP
uniprot id: A0A6P7ZEM8
uniprot id: A0A6P7ZK41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HOP2 family.
messages: Nucleus

1415580:OCLN
gene id: 1415580:OCLN
uniprot id: A0A6P7X0W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
messages: Membrane
messages: tight junction

1415580:PLOD3
gene id: 1415580:PLOD3
uniprot id: A0A6P7WMJ0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

1415580:LOC115458360
gene id: 1415580:LOC115458360
uniprot id: A0A6P7WUQ0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:KLHL3
gene id: 1415580:KLHL3
uniprot id: A0A6P7YN32
uniprot id: A0A6P7YVS7
uniprot id: A0A6P7YZ23
names: Subcellular Location Annotation
messages: cytoskeleton
messages: cytosol

1415580:AP1B1
gene id: 1415580:AP1B1
uniprot id: A0A6P7Z9W9
uniprot id: A0A6P7ZDA3
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

1415580:KCNC4
gene id: 1415580:KCNC4
uniprot id: A0A6P7ZCP1
names: Subcellular Location Annotation
messages: Membrane

1415580:ALDH8A1
gene id: 1415580:ALDH8A1
uniprot id: A0A6P7XFK1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1415580:LOC115457917
gene id: 1415580:LOC115457917
uniprot id: A0A6P7WJI2
names: Subcellular Location Annotation
messages: Membrane

1415580:TGM2
gene id: 1415580:TGM2
uniprot id: A0A6P7YVZ4
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

1415580:LOC115463300
gene id: 1415580:LOC115463300
uniprot id: A0A6P7XFW6
names: Similarity
messages: Belongs to the FBPase class 1 family.

1415580:LOC115458146
gene id: 1415580:LOC115458146
uniprot id: A0A6P7X135
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:HOMER1
gene id: 1415580:HOMER1
uniprot id: A0A6P7X720
uniprot id: A0A6P7XEL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

1415580:TBX4
gene id: 1415580:TBX4
uniprot id: A0A6P7WFR9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

1415580:SNTG2
gene id: 1415580:SNTG2
uniprot id: A0A6P7XL16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: cytoskeleton

1415580:NR1H3
gene id: 1415580:NR1H3
uniprot id: A0A6P7XUU5
uniprot id: A0A6P7Y150
uniprot id: A0A6P7Y1Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

1415580:PPTC7
gene id: 1415580:PPTC7
uniprot id: A0A6P7ZDT7
names: Similarity
messages: Belongs to the PP2C family.

1415580:TRAPPC9
gene id: 1415580:TRAPPC9
uniprot id: A0A6P7Z7S9
uniprot id: A0A6P7ZGD2
names: Similarity
messages: Belongs to the NIBP family.

1415580:FOLH1B
gene id: 1415580:FOLH1B
uniprot id: A0A6P7XU33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

1415580:COPS6
gene id: 1415580:COPS6
uniprot id: A0A6P7WP53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M67A family. CSN6 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.
messages: Cytoplasm
messages: Nucleus

1415580:TRHR
gene id: 1415580:TRHR
uniprot id: A0A6P7X663
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

1415580:LOC115477343
gene id: 1415580:LOC115477343
uniprot id: A0A6P7YZS4
uniprot id: A0A6P7Z3H2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Secreted

1415580:LOC115458439
gene id: 1415580:LOC115458439
uniprot id: A0A6P7WSV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:QTRT2
gene id: 1415580:QTRT2
uniprot id: A0A6P7Y760
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Heterodimer of a catalytic subunit QTRT1 and an accessory subunit QTRT2.
messages: Mitochondrion outer membrane
messages: Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).

1415580:LOC115471045
gene id: 1415580:LOC115471045
uniprot id: A0A6P7Y6I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

1415580:AMFR
gene id: 1415580:AMFR
uniprot id: A0A6P7XVU9
uniprot id: A0A6P7Y351
uniprot id: A0A6P7Y3W0
names: Subcellular Location Annotation
messages: Membrane

1415580:SNCG
gene id: 1415580:SNCG
uniprot id: A0A6P7XUS4
uniprot id: A0A6P7Y300
names: Similarity
names: Subunit
messages: Belongs to the synuclein family.
messages: May be a centrosome-associated protein. Interacts with MYOC; affects its secretion and its aggregation.

1415580:LOC115459799
gene id: 1415580:LOC115459799
uniprot id: A0A6P7X4E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

1415580:EXOC1
gene id: 1415580:EXOC1
uniprot id: A0A6P7X481
uniprot id: A0A6P7XAW0
names: Similarity
messages: Belongs to the SEC3 family.

1415580:LOC115475174
gene id: 1415580:LOC115475174
uniprot id: A0A6P7YHA5
uniprot id: A0A6P7YQ06
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1415580:LYN
gene id: 1415580:LYN
uniprot id: A0A6P7YTD9
uniprot id: A0A6P7YZP8
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

1415580:BASP1
gene id: 1415580:BASP1
uniprot id: A0A6P7YJD8
names: Similarity
messages: Belongs to the BASP1 family.

1415580:TIMM21
gene id: 1415580:TIMM21
uniprot id: A0A6P7YUJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM21 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane

1415580:MIOS
gene id: 1415580:MIOS
uniprot id: A0A6P7XWD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat mio family.
messages: Lysosome membrane

1415580:LOC115461996
gene id: 1415580:LOC115461996
uniprot id: A0A6P7XBG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:DHX15
gene id: 1415580:DHX15
uniprot id: A0A6P7X151
uniprot id: A0A6P7XAE6
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.

1415580:LOC115463103
gene id: 1415580:LOC115463103
uniprot id: A0A6P7X0V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTF2H2 family.
messages: Nucleus

1415580:BAP1
gene id: 1415580:BAP1
uniprot id: A0A6P7Y105
names: Similarity
messages: Belongs to the peptidase C12 family.

1415580:DVL2
gene id: 1415580:DVL2
uniprot id: A0A6P7WQ34
names: Similarity
messages: Belongs to the DSH family.

1415580:LOC115457613
gene id: 1415580:LOC115457613
uniprot id: A0A6P7WPG2
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

1415580:LOC115473506
gene id: 1415580:LOC115473506
uniprot id: A0A6P7YA94
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115481142
gene id: 1415580:LOC115481142
uniprot id: A0A6P7ZQU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

1415580:AP1M2
gene id: 1415580:AP1M2
uniprot id: A0A6P7XR55
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

1415580:NSG2
gene id: 1415580:NSG2
uniprot id: A0A6P7YYU2
names: Similarity
messages: Belongs to the NSG family.

1415580:CAPN9
gene id: 1415580:CAPN9
uniprot id: A0A6P7XIN1
names: Similarity
messages: Belongs to the peptidase C2 family.

1415580:SLC20A2
gene id: 1415580:SLC20A2
uniprot id: A0A6P7XAR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.

1415580:JUP
gene id: 1415580:JUP
uniprot id: A0A6P7ZEV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: Membrane
messages: desmosome

1415580:PPP1R3C
gene id: 1415580:PPP1R3C
uniprot id: A0A6P7XTX6
names: Domain
names: Function
names: Subunit
messages: Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown.
messages: Interacts with PPP1CC catalytic subunit of PP1 and associates with glycogen. Forms complexes with glycogen phosphorylase, glycogen synthase and phosphorylase kinase which is necessary for its regulation of PP1 activity.
messages: The N-terminal region is required for binding to PP1, the central region is required for binding to glycogen and the C-terminal region is required for binding to glycogen phosphorylase glycogen synthase and phosphorylase kinase.

1415580:LOC115466486
gene id: 1415580:LOC115466486
uniprot id: A0A6P7XK54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actinoporin family. Sea anemone subfamily.
messages: Cell membrane
messages: Membrane
messages: Nematocyst
messages: Target cell membrane

1415580:PCNP
gene id: 1415580:PCNP
uniprot id: A0A6P7YB06
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with UHRF2/NIRF.
messages: May be involved in cell cycle regulation.
messages: Nucleus

1415580:CPSF7
gene id: 1415580:CPSF7
uniprot id: A0A6P7Y1V9
uniprot id: A0A6P7Y2F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Nucleus

1415580:SGSM2
gene id: 1415580:SGSM2
uniprot id: A0A6P7WEL7
uniprot id: A0A6P7WMR0
uniprot id: A0A6P7WTP8
uniprot id: A0A6P7WUQ8
names: Similarity
messages: Belongs to the RUTBC family.

1415580:LOC115460256
gene id: 1415580:LOC115460256
uniprot id: A0A6P7X6X0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:LOC115481218
gene id: 1415580:LOC115481218
uniprot id: A0A6P7WV85
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1415580:LOC115458242
gene id: 1415580:LOC115458242
uniprot id: A0A6P7WKU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:CELF2
gene id: 1415580:CELF2
uniprot id: A0A6P7Z149
uniprot id: A0A6P7Z6J3
uniprot id: A0A6P7Z904
uniprot id: A0A6P7Z909
uniprot id: A0A6P7ZBM8
uniprot id: A0A6P7ZBN2
uniprot id: A0A6P7ZCI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

1415580:GPR4
gene id: 1415580:GPR4
uniprot id: A0A6P7ZJB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115471359
gene id: 1415580:LOC115471359
uniprot id: A0A6P7Y7G9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115457444
gene id: 1415580:LOC115457444
uniprot id: A0A6P7WQS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

1415580:E2F5
gene id: 1415580:E2F5
uniprot id: A0A6P7Z5R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

1415580:BTK
gene id: 1415580:BTK
uniprot id: A0A6P7YR24
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

1415580:LOC115481764
gene id: 1415580:LOC115481764
uniprot id: A0A6P7ZGG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.2/KCNA2 sub-subfamily.
messages: Cell membrane
messages: Membrane

1415580:SLC34A2
gene id: 1415580:SLC34A2
uniprot id: A0A6P7X3T5
uniprot id: A0A6P7XAG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Involved in actively transporting phosphate into cells via Na(+) cotransport.
messages: Membrane

1415580:LOC115458442
gene id: 1415580:LOC115458442
uniprot id: A0A6P7WV76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:CSTF3
gene id: 1415580:CSTF3
uniprot id: A0A6P7XVH2
names: Subcellular Location Annotation
messages: Nucleus

1415580:SGO1
gene id: 1415580:SGO1
uniprot id: A0A6P7Y690
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

1415580:LOC115461440
gene id: 1415580:LOC115461440
uniprot id: A0A6P7X959
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:DOK4
gene id: 1415580:DOK4
uniprot id: A0A6P7YCK9
names: Similarity
messages: Belongs to the DOK family. Type B subfamily.

1415580:LOC115465974
gene id: 1415580:LOC115465974
uniprot id: A0A6P7XPY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

1415580:TEX261
gene id: 1415580:TEX261
uniprot id: A0A6P7X8G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVP26 family.
messages: Membrane

1415580:SPSB4
gene id: 1415580:SPSB4
uniprot id: A0A6P7YZH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

1415580:CCS
gene id: 1415580:CCS
uniprot id: A0A6P7Z6N7
uniprot id: A0A6P7ZEW0
names: Similarity
messages: In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family.

1415580:LOC115478993
gene id: 1415580:LOC115478993
uniprot id: A0A6P7Z7E9
names: Function
names: Subunit
messages: Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.
messages: Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.

1415580:ABL2
gene id: 1415580:ABL2
uniprot id: A0A6P7YBI6
uniprot id: A0A6P7YHN6
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

1415580:LTK
gene id: 1415580:LTK
uniprot id: A0A6P7YVS4
names: Caution
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:CRYBG3
gene id: 1415580:CRYBG3
uniprot id: A0A6P7YAR6
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

1415580:PPP2CB
gene id: 1415580:PPP2CB
uniprot id: A0A6P7XJ98
names: Similarity
messages: Belongs to the PPP phosphatase family.

1415580:POFUT2
gene id: 1415580:POFUT2
uniprot id: A0A6P7YSV5
names: Similarity
messages: Belongs to the glycosyltransferase 68 family.

1415580:YWHAG
gene id: 1415580:YWHAG
uniprot id: A0A6P7ZYB0
names: Function
names: Similarity
messages: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
messages: Belongs to the 14-3-3 family.

1415580:DNAH3
gene id: 1415580:DNAH3
uniprot id: A0A6P7YLA8
names: Similarity
messages: Belongs to the dynein heavy chain family.

1415580:NAPRT
gene id: 1415580:NAPRT
uniprot id: A0A6P7ZHZ0
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Helps prevent cellular oxidative stress via its role in NAD biosynthesis.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1415580:LHPP
gene id: 1415580:LHPP
uniprot id: A0A6P7YC31
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1415580:LOC115479198
gene id: 1415580:LOC115479198
uniprot id: A0A6P7ZB40
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

1415580:EYA1
gene id: 1415580:EYA1
uniprot id: A0A6P7YW15
uniprot id: A0A6P7YW23
uniprot id: A0A6P7Z243
uniprot id: A0A6P7Z3Q3
uniprot id: A0A6P7Z3U3
uniprot id: A0A6P7Z3V8
uniprot id: A0A6P7Z6H2
uniprot id: A0A6P7Z6L4
uniprot id: A0A6P7Z7K1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

1415580:LOC115472759
gene id: 1415580:LOC115472759
uniprot id: A0A6P7YJA6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:NIBAN1
gene id: 1415580:NIBAN1
uniprot id: A0A6P7YA10
names: Similarity
messages: Belongs to the Niban family.

1415580:LOC115481407
gene id: 1415580:LOC115481407
uniprot id: A0A6P7ZQ91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

1415580:HOPX
gene id: 1415580:HOPX
uniprot id: A0A6P7XAT2
names: Subcellular Location Annotation
messages: Nucleus

1415580:NOB1
gene id: 1415580:NOB1
uniprot id: A0A6P7XYS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOB1 family.
messages: May play a role in mRNA degradation.
messages: Nucleus

1415580:LOC115481529
gene id: 1415580:LOC115481529
uniprot id: A0A6P7ZB75
uniprot id: A0A6P7ZNH3
names: Similarity
messages: Belongs to the intermediate filament family.

1415580:KIZ
gene id: 1415580:KIZ
uniprot id: A0A6P7XN68
uniprot id: A0A6P7XNT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kizuna family.
messages: Centrosomal protein required for establishing a robust mitotic centrosome architecture that can endure the forces that converge on the centrosomes during spindle formation. Required for stabilizing the expanded pericentriolar material around the centriole.
messages: centrosome
messages: cilium basal body

1415580:LOC115475538
gene id: 1415580:LOC115475538
uniprot id: A0A6P7YQB4
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

1415580:LRP1
gene id: 1415580:LRP1
uniprot id: A0A6P7XH35
names: Caution
names: Similarity
messages: Belongs to the LDLR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:ATP11B
gene id: 1415580:ATP11B
uniprot id: A0A6P7Z763
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

1415580:RNPEPL1
gene id: 1415580:RNPEPL1
uniprot id: A0A6P7Z7K3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1415580:LOC115458815
gene id: 1415580:LOC115458815
uniprot id: A0A6P7WMR1
names: Similarity
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.

1415580:ND3
gene id: 1415580:ND3
uniprot id: W5RH65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I.
messages: Mitochondrion membrane

1415580:VDAC2
gene id: 1415580:VDAC2
uniprot id: A0A6P7Y7J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Mitochondrion outer membrane

1415580:UBL3
gene id: 1415580:UBL3
uniprot id: A0A6P7XZQ7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:RGMA
gene id: 1415580:RGMA
uniprot id: A0A6P7X4T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

1415580:EGFL6
gene id: 1415580:EGFL6
uniprot id: A0A6P7XIX6
uniprot id: A0A6P7XQS3
names: Caution
names: Similarity
messages: Belongs to the nephronectin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115457038
gene id: 1415580:LOC115457038
uniprot id: A0A6P7WVP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115470140
gene id: 1415580:LOC115470140
uniprot id: A0A6P7Y780
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan alpha/epsilon family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
messages: Golgi apparatus
messages: dendrite
messages: sarcolemma

1415580:LOC115471850
gene id: 1415580:LOC115471850
uniprot id: A0A6P7Y261
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

1415580:LOC115461167
gene id: 1415580:LOC115461167
uniprot id: A0A6P7WZT6
names: Similarity
messages: Belongs to the cytochrome P450 family.

1415580:AKAP4
gene id: 1415580:AKAP4
uniprot id: A0A6P7YKS9
names: Similarity
messages: Belongs to the AKAP110 family.

1415580:CFL2
gene id: 1415580:CFL2
uniprot id: A0A6P7Z1F1
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

1415580:PLD5
gene id: 1415580:PLD5
uniprot id: A0A6P7XIL2
uniprot id: A0A6P7XPJ8
names: Similarity
messages: Belongs to the phospholipase D family.

1415580:ETV2
gene id: 1415580:ETV2
uniprot id: A0A6P7YRU0
uniprot id: A0A6P7YWL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

1415580:LOC115464439
gene id: 1415580:LOC115464439
uniprot id: A0A6P7XK43
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:TMEM39A
gene id: 1415580:TMEM39A
uniprot id: A0A6P7Y3W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM39 family.
messages: Membrane

1415580:CAPZB
gene id: 1415580:CAPZB
uniprot id: A0A6P7ZFN3
uniprot id: A0A6P7ZW69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the F-actin-capping protein beta subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.
messages: cytoskeleton

1415580:GRIA3
gene id: 1415580:GRIA3
uniprot id: A0A6P7YK06
uniprot id: A0A6P7YPM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

1415580:ATG7
gene id: 1415580:ATG7
uniprot id: A0A6P7Y9C3
uniprot id: A0A6P7YFI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG7 family.
messages: Cytoplasm
messages: E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Modulates p53/TP53 activity to regulate cell cycle and survival during metabolic stress.
messages: Homodimer.
messages: Preautophagosomal structure

1415580:LOC115480231
gene id: 1415580:LOC115480231
uniprot id: A0A6P7ZDQ3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:UBLCP1
gene id: 1415580:UBLCP1
uniprot id: A0A6P7YV34
names: Function
names: Subcellular Location Annotation
messages: Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome.
messages: Nucleus

1415580:MPP2
gene id: 1415580:MPP2
uniprot id: A0A6P7ZDI3
uniprot id: A0A6P7ZIE2
uniprot id: A0A6P7ZVV6
names: Similarity
messages: Belongs to the MAGUK family.

1415580:ELN
gene id: 1415580:ELN
uniprot id: A0A6P7WFZ1
uniprot id: A0A6P7WFZ5
uniprot id: A0A6P7WM42
uniprot id: A0A6P7WM48
uniprot id: A0A6P7WP40
uniprot id: A0A6P7WP45
uniprot id: A0A6P7WV38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elastin family.
messages: extracellular matrix

1415580:CENPL
gene id: 1415580:CENPL
uniprot id: A0A6P7YAK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-L/IML3 family.
messages: Nucleus

1415580:CD164L2
gene id: 1415580:CD164L2
uniprot id: A0A6P7Z7P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD164 family.
messages: Membrane

1415580:POP7
gene id: 1415580:POP7
uniprot id: A0A6P7WYG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like Alba family.
messages: Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences.
messages: nucleolus

1415580:LOC115464322
gene id: 1415580:LOC115464322
uniprot id: A0A6P7XIS8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:CNOT8
gene id: 1415580:CNOT8
uniprot id: A0A6P7YJU5
uniprot id: A0A6P7YST5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

1415580:LOC115466745
gene id: 1415580:LOC115466745
uniprot id: A0A6P7XND7
names: Similarity
messages: Belongs to the intermediate filament family.

1415580:LOC115474681
gene id: 1415580:LOC115474681
uniprot id: A0A6P7YM95
uniprot id: A0A6P7YSB2
uniprot id: A0A6P7YSF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

1415580:KIAA1324L
gene id: 1415580:KIAA1324L
uniprot id: A0A6P7Z9U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELAPOR family.
messages: Cell membrane
messages: Membrane

1415580:LOC115458365
gene id: 1415580:LOC115458365
uniprot id: A0A6P7X0R5
uniprot id: A0A6P7X1X8
names: Similarity
messages: Belongs to the NXPE family.

1415580:RITA1
gene id: 1415580:RITA1
uniprot id: A0A6P7Z716
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RITA family.
messages: Cytoplasm
messages: Interacts with RBPJ/RBPSUH.
messages: Nucleus
messages: Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.

1415580:EPC2
gene id: 1415580:EPC2
uniprot id: A0A6P7YIX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enhancer of polycomb family.
messages: Nucleus

1415580:TULP4
gene id: 1415580:TULP4
uniprot id: A0A6P7XFF6
uniprot id: A0A6P7XUD4
names: Similarity
messages: Belongs to the TUB family.

1415580:TSPAN3
gene id: 1415580:TSPAN3
uniprot id: A0A6P7WIM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

1415580:HGD
gene id: 1415580:HGD
uniprot id: A0A6P7Y431
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

1415580:LOC115474088
gene id: 1415580:LOC115474088
uniprot id: A0A6P7YJY0
names: Similarity
messages: Belongs to the polycystin family.

1415580:TAFA4
gene id: 1415580:TAFA4
uniprot id: A0A6P7YG27
names: Similarity
messages: Belongs to the TAFA family.

1415580:AASS
gene id: 1415580:AASS
uniprot id: A0A6P7Z911
names: Similarity
messages: In the C-terminal section; belongs to the saccharopine dehydrogenase family.
messages: In the N-terminal section; belongs to the AlaDH/PNT family.

1415580:LOC115461183
gene id: 1415580:LOC115461183
uniprot id: A0A6P7X7X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LSS
gene id: 1415580:LSS
uniprot id: A0A6P7YTT4
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

1415580:WNT9A
gene id: 1415580:WNT9A
uniprot id: A0A6P7XRS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

1415580:FMNL2
gene id: 1415580:FMNL2
uniprot id: A0A6P7YB91
names: Similarity
messages: Belongs to the formin homology family.

1415580:EPCAM
gene id: 1415580:EPCAM
uniprot id: A0A6P7XGT9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPCAM family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:LOC115471898
gene id: 1415580:LOC115471898
uniprot id: A0A6P7Y2E3
uniprot id: A0A6P7YFP2
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the aldo/keto reductase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

1415580:ADAM23
gene id: 1415580:ADAM23
uniprot id: A0A6P7YRK0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:PSMD8
gene id: 1415580:PSMD8
uniprot id: A0A6P7ZCH6
names: Similarity
messages: Belongs to the proteasome subunit S14 family.

1415580:IPO7
gene id: 1415580:IPO7
uniprot id: A0A6P7XND4
names: Subcellular Location Annotation
messages: Cytoplasm

1415580:LOC115466341
gene id: 1415580:LOC115466341
uniprot id: A0A6P7XCV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

1415580:GRM5
gene id: 1415580:GRM5
uniprot id: A0A6P7XSJ0
uniprot id: A0A6P7XZ33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

1415580:ITPRIPL2
gene id: 1415580:ITPRIPL2
uniprot id: A0A6P7YXU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Membrane

1415580:LOC115456715
gene id: 1415580:LOC115456715
uniprot id: A0A6P7WUC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

1415580:LOC115464728
gene id: 1415580:LOC115464728
uniprot id: A0A6P7XJZ5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:XRCC6
gene id: 1415580:XRCC6
uniprot id: A0A6P7YFD8
names: Subcellular Location Annotation
messages: Nucleus

1415580:MYRFL
gene id: 1415580:MYRFL
uniprot id: A0A6P7Z5B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRF family.
messages: Membrane

1415580:ATAD2
gene id: 1415580:ATAD2
uniprot id: A0A6P7ZAJ9
uniprot id: A0A6P7ZDN8
uniprot id: A0A6P7ZGQ7
names: Similarity
messages: Belongs to the AAA ATPase family.

1415580:CASK
gene id: 1415580:CASK
uniprot id: A0A6P7XS31
uniprot id: A0A6P7Y067
uniprot id: A0A6P7Y523
uniprot id: A0A6P7Y632
names: Similarity
messages: Belongs to the MAGUK family.

1415580:GSG1L
gene id: 1415580:GSG1L
uniprot id: A0A6P7YXH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

1415580:PEAR1
gene id: 1415580:PEAR1
uniprot id: A0A6P7WRM6
uniprot id: A0A6P7WZX9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:BAZ2B
gene id: 1415580:BAZ2B
uniprot id: A0A6P7YGJ5
names: Similarity
messages: Belongs to the WAL family.

1415580:MANBAL
gene id: 1415580:MANBAL
uniprot id: A0A6P7YJZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0239 family.
messages: Membrane

1415580:EWSR1
gene id: 1415580:EWSR1
uniprot id: A0A6P7Z944
uniprot id: A0A6P7ZBZ0
uniprot id: A0A6P7ZEP1
uniprot id: A0A6P7ZF87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TET family.
messages: Nucleus

1415580:PTEN
gene id: 1415580:PTEN
uniprot id: A0A6P7Y845
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4.
messages: Belongs to the PTEN phosphatase protein family.
messages: Cytoplasm
messages: Nucleus
messages: PML body
messages: Postsynaptic density
messages: dendritic spine

1415580:NAT10
gene id: 1415580:NAT10
uniprot id: A0A6P7XMM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.
messages: Interacts with THUMPD1.
messages: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA-binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
messages: nucleolus

1415580:LOC115462013
gene id: 1415580:LOC115462013
uniprot id: A0A6P7X3G5
names: Subcellular Location Annotation
messages: Nucleus

1415580:ITM2A
gene id: 1415580:ITM2A
uniprot id: A0A6P7YQ95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

1415580:TMLHE
gene id: 1415580:TMLHE
uniprot id: A0A6P7YPZ3
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

1415580:LOC115478132
gene id: 1415580:LOC115478132
uniprot id: A0A6P7Z686
names: Similarity
messages: Belongs to the actin family.

1415580:MTM1
gene id: 1415580:MTM1
uniprot id: A0A6P7YIR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cell membrane
messages: Late endosome
messages: filopodium
messages: ruffle
messages: sarcomere

1415580:ATP6V1G1
gene id: 1415580:ATP6V1G1
uniprot id: A0A6P7YDJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

1415580:B3GNT2
gene id: 1415580:B3GNT2
uniprot id: A0A6P7XNN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

1415580:LOC115480901
gene id: 1415580:LOC115480901
uniprot id: A0A6P7ZME2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

1415580:ODC1
gene id: 1415580:ODC1
uniprot id: A0A6P7XGU8
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1415580:EBF2
gene id: 1415580:EBF2
uniprot id: A0A6P7XXK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

1415580:LOC115481467
gene id: 1415580:LOC115481467
uniprot id: A0A6P7ZTH1
names: Similarity
messages: Belongs to the Nav/unc-53 family.

1415580:LOC115479211
gene id: 1415580:LOC115479211
uniprot id: A0A6P7Z8G9
names: Subcellular Location Annotation
messages: Membrane

1415580:VANGL1
gene id: 1415580:VANGL1
uniprot id: A0A6P7Y3R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

1415580:PPFIA1
gene id: 1415580:PPFIA1
uniprot id: A0A6P7XMK9
uniprot id: A0A6P7XML2
uniprot id: A0A6P7XUD1
uniprot id: A0A6P7XUD6
uniprot id: A0A6P7XVR0
uniprot id: A0A6P7XVR4
uniprot id: A0A6P7Y0N5
uniprot id: A0A6P7Y198
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

1415580:LOC115457072
gene id: 1415580:LOC115457072
uniprot id: A0A6P7WWR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

1415580:RRM2
gene id: 1415580:RRM2
uniprot id: A0A6P7XGV4
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

1415580:CLVS2
gene id: 1415580:CLVS2
uniprot id: A0A6P7XL59
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Vesicle
messages: clathrin-coated vesicle
messages: trans-Golgi network membrane

1415580:RPS7
gene id: 1415580:RPS7
uniprot id: A0A6P7XWC6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS7 family.

1415580:MRPL10
gene id: 1415580:MRPL10
uniprot id: A0A6P7ZIA8
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

1415580:CLDN20
gene id: 1415580:CLDN20
uniprot id: A0A6P7XFV7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

1415580:CLCNKA
gene id: 1415580:CLCNKA
uniprot id: A0A6P7ZL02
uniprot id: A0A6P7ZV99
uniprot id: A0A6P7ZVW2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:METAP1D
gene id: 1415580:METAP1D
uniprot id: A0A6P7YK88
uniprot id: A0A6P7YKS5
uniprot id: A0A6P7YQ72
uniprot id: A0A6P7YQJ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family.
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

1415580:SIX2
gene id: 1415580:SIX2
uniprot id: A0A6P7XAZ3
uniprot id: A0A6P7XII3
names: Subcellular Location Annotation
messages: Nucleus

1415580:PUS10
gene id: 1415580:PUS10
uniprot id: A0A6P7XFS4
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.

1415580:SDC3
gene id: 1415580:SDC3
uniprot id: A0A6P7ZFL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

1415580:CCDC124
gene id: 1415580:CCDC124
uniprot id: A0A6P7Z792
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CCDC124 family.
messages: Interacts with RASGEF1B.
messages: Required for proper progression of late cytokinetic stages.

1415580:LAMC1
gene id: 1415580:LAMC1
uniprot id: A0A6P7YK73
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

1415580:FAM120B
gene id: 1415580:FAM120B
uniprot id: A0A6P7XF37
uniprot id: A0A6P7XMC3
uniprot id: A0A6P7XN34
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

1415580:BAZ1A
gene id: 1415580:BAZ1A
uniprot id: A0A6P7YYA6
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115473197
gene id: 1415580:LOC115473197
uniprot id: A0A6P7YLD7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

1415580:PCMT1
gene id: 1415580:PCMT1
uniprot id: A0A6P7XFN3
uniprot id: A0A6P7XP79
uniprot id: A0A6P7XV42
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1415580:LOC115474893
gene id: 1415580:LOC115474893
uniprot id: A0A6P7YT61
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

1415580:ARPC4
gene id: 1415580:ARPC4
uniprot id: A0A6P7Y1A5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARPC4 family.
messages: Cell projection
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
messages: cytoskeleton

1415580:LOC115481224
gene id: 1415580:LOC115481224
uniprot id: A0A6P7X5J9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1415580:LOC115476065
gene id: 1415580:LOC115476065
uniprot id: A0A6P7YTS1
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1415580:LOC115457074
gene id: 1415580:LOC115457074
uniprot id: A0A6P7WGI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:TADA1
gene id: 1415580:TADA1
uniprot id: A0A6P7YBD1
uniprot id: A0A6P7YHI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TADA1 family.
messages: Nucleus
messages: Probably involved in transcriptional regulation.

1415580:HSD17B8
gene id: 1415580:HSD17B8
uniprot id: A0A6P7XKQ2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1415580:LOC115461697
gene id: 1415580:LOC115461697
uniprot id: A0A6P7X533
names: Similarity
messages: Belongs to the MS4A family.

1415580:GOLPH3L
gene id: 1415580:GOLPH3L
uniprot id: A0A6P7WY80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

1415580:LOC115457196
gene id: 1415580:LOC115457196
uniprot id: A0A6P7WN53
names: Subcellular Location Annotation
messages: Membrane

1415580:ALDH4A1
gene id: 1415580:ALDH4A1
uniprot id: A0A6P7WP20
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1415580:DVL3
gene id: 1415580:DVL3
uniprot id: A0A6P7YY99
uniprot id: A0A6P7Z3Y0
uniprot id: A0A6P7Z658
uniprot id: A0A6P7Z8U7
uniprot id: A0A6P7Z9K8
names: Similarity
messages: Belongs to the DSH family.

1415580:LOC115471602
gene id: 1415580:LOC115471602
uniprot id: A0A6P7Y0V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

1415580:FBLN2
gene id: 1415580:FBLN2
uniprot id: A0A6P7YAY1
uniprot id: A0A6P7YGI4
names: Caution
names: Similarity
messages: Belongs to the fibulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:URAD
gene id: 1415580:URAD
uniprot id: A0A6P7XXR0
names: Function
names: Similarity
messages: Belongs to the OHCU decarboxylase family.
messages: Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin.

1415580:BRIX1
gene id: 1415580:BRIX1
uniprot id: A0A6P7X6G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRX1 family.
messages: Required for biogenesis of the 60S ribosomal subunit.
messages: nucleolus

1415580:LOC115457379
gene id: 1415580:LOC115457379
uniprot id: A0A6P7WQK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:EIF4EBP2
gene id: 1415580:EIF4EBP2
uniprot id: A0A6P7Y2J9
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

1415580:KYAT3
gene id: 1415580:KYAT3
uniprot id: A0A6P7Y396
uniprot id: A0A6P7Y3A1
uniprot id: A0A6P7YAB5
uniprot id: A0A6P7YAB9
uniprot id: A0A6P7YAM9
uniprot id: A0A6P7YFV9
uniprot id: A0A6P7YFW3
uniprot id: A0A6P7YGI5
names: Subunit
messages: Homodimer.

1415580:SFPQ
gene id: 1415580:SFPQ
uniprot id: A0A6P7ZJS6
uniprot id: A0A6P7ZNM7
uniprot id: A0A6P7ZQR7
names: Subcellular Location Annotation
messages: Nucleus speckle

1415580:LOC115461938
gene id: 1415580:LOC115461938
uniprot id: A0A6P7XCG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115461997
gene id: 1415580:LOC115461997
uniprot id: A0A6P7X3F2
names: Similarity
messages: Belongs to the TAFA family.

1415580:MYRF
gene id: 1415580:MYRF
uniprot id: A0A6P7XWX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRF family.
messages: Membrane

1415580:LOC115477824
gene id: 1415580:LOC115477824
uniprot id: A0A6P7Z214
names: Subcellular Location Annotation
messages: Cytoplasm

1415580:LOC115476916
gene id: 1415580:LOC115476916
uniprot id: A0A6P7YWM1
names: Subcellular Location Annotation
messages: Membrane

1415580:DDR2
gene id: 1415580:DDR2
uniprot id: A0A6P7YID8
names: Subcellular Location Annotation
messages: Membrane

1415580:CAPN11
gene id: 1415580:CAPN11
uniprot id: A0A6P7XEG8
names: Similarity
messages: Belongs to the peptidase C2 family.

1415580:UBE3A
gene id: 1415580:UBE3A
uniprot id: A0A6P7Y320
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
messages: Nucleus

1415580:ELAC1
gene id: 1415580:ELAC1
uniprot id: A0A6P7XB72
names: Subunit
messages: Homodimer.

1415580:GJD2
gene id: 1415580:GJD2
uniprot id: A0A6P7YYB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

1415580:NAT9
gene id: 1415580:NAT9
uniprot id: A0A6P7Y3V8
uniprot id: A0A6P7YB94
uniprot id: A0A6P7YH26
names: Similarity
messages: Belongs to the acetyltransferase family. GNAT subfamily.

1415580:PODXL2
gene id: 1415580:PODXL2
uniprot id: A0A6P7YAD9
names: Subcellular Location Annotation
messages: Membrane

1415580:ANO2
gene id: 1415580:ANO2
uniprot id: A0A6P7Z5W4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:ADORA2A
gene id: 1415580:ADORA2A
uniprot id: A0A6P7ZJS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

1415580:NEO1
gene id: 1415580:NEO1
uniprot id: A0A6P7XB58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. DCC family.
messages: Membrane

1415580:ARRDC2
gene id: 1415580:ARRDC2
uniprot id: A0A6P7Z8R4
uniprot id: A0A6P7ZE95
names: Similarity
messages: Belongs to the arrestin family.

1415580:E2F2
gene id: 1415580:E2F2
uniprot id: A0A6P7ZMB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

1415580:AKR1D1
gene id: 1415580:AKR1D1
uniprot id: A0A6P7Z2A3
names: Similarity
messages: Belongs to the aldo/keto reductase family.

1415580:LOC115456972
gene id: 1415580:LOC115456972
uniprot id: A0A6P7WVE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115457727
gene id: 1415580:LOC115457727
uniprot id: A0A6P7WXZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115462543
gene id: 1415580:LOC115462543
uniprot id: A0A6P7XDY9
names: Similarity
messages: Belongs to the intermediate filament family.

1415580:RELL1
gene id: 1415580:RELL1
uniprot id: A0A6P7XAI8
names: Similarity
messages: Belongs to the RELT family.

1415580:DSG2
gene id: 1415580:DSG2
uniprot id: A0A6P7YXJ7
uniprot id: A0A6P7YYQ5
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

1415580:SH2B3
gene id: 1415580:SH2B3
uniprot id: A0A6P7ZBY6
uniprot id: A0A6P7ZCU0
names: Similarity
messages: Belongs to the SH2B adapter family.

1415580:LOC115476787
gene id: 1415580:LOC115476787
uniprot id: A0A6P7YXF2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:LOC115457189
gene id: 1415580:LOC115457189
uniprot id: A0A6P7WX25
names: Subcellular Location Annotation
messages: Membrane

1415580:THBS3
gene id: 1415580:THBS3
uniprot id: A0A6P7WJM5
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOXL2
gene id: 1415580:LOXL2
uniprot id: A0A6P7XYM1
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Contains 1 lysine tyrosylquinone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

1415580:WFIKKN1
gene id: 1415580:WFIKKN1
uniprot id: A0A6P7YI04
names: Similarity
messages: Belongs to the WFIKKN family.

1415580:LOC115464339
gene id: 1415580:LOC115464339
uniprot id: A0A6P7X4P1
names: Similarity
messages: Belongs to the tumor necrosis factor family.

1415580:RBBP8
gene id: 1415580:RBBP8
uniprot id: A0A6P7YWJ2
uniprot id: A0A6P7YWK7
uniprot id: A0A6P7Z1J9
uniprot id: A0A6P7Z1L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COM1/SAE2/CtIP family.
messages: Nucleus

1415580:SHROOM4
gene id: 1415580:SHROOM4
uniprot id: A0A6P7YP46
uniprot id: A0A6P7YTD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

1415580:LOC115481214
gene id: 1415580:LOC115481214
uniprot id: A0A6P7ZRN7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1415580:LOC115469426
gene id: 1415580:LOC115469426
uniprot id: A0A6P7Y4A7
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family.

1415580:LOC115474932
gene id: 1415580:LOC115474932
uniprot id: A0A6P7YP28
names: Function
names: Similarity
messages: Belongs to the TMEM177 family.
messages: Plays a role in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation and is required for the stabilization of COX20 and the newly synthesized MT-CO2/COX2 protein.

1415580:AMZ1
gene id: 1415580:AMZ1
uniprot id: A0A6P7YTY3
names: Function
names: Similarity
messages: Belongs to the peptidase M54 family.
messages: Probable zinc metalloprotease.

1415580:SLC1A5
gene id: 1415580:SLC1A5
uniprot id: A0A6P7ZD94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1415580:SIRT2
gene id: 1415580:SIRT2
uniprot id: A0A6P7Z6G6
uniprot id: A0A6P7ZBC8
uniprot id: A0A6P7ZHT3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.
messages: Binds 1 zinc ion per subunit.
messages: NAD-dependent protein deacetylase.

1415580:CC2D1A
gene id: 1415580:CC2D1A
uniprot id: A0A6P7XB00
names: Similarity
messages: Belongs to the CC2D1 family.

1415580:LOC115458421
gene id: 1415580:LOC115458421
uniprot id: A0A6P7X276
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

1415580:LOC115481517
gene id: 1415580:LOC115481517
uniprot id: A0A6P7ZFE9
uniprot id: A0A6P7ZNF3
uniprot id: A0A6P7ZRD9
uniprot id: A0A6P7ZU18
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

1415580:LOC115480966
gene id: 1415580:LOC115480966
uniprot id: A0A6P7WW72
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1415580:KCNF1
gene id: 1415580:KCNF1
uniprot id: A0A6P7XNL8
names: Subcellular Location Annotation
messages: Membrane

1415580:PRPSAP1
gene id: 1415580:PRPSAP1
uniprot id: A0A6P7Y9A7
uniprot id: A0A6P7YGK2
uniprot id: A0A6P7YLY9
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1415580:GMDS
gene id: 1415580:GMDS
uniprot id: A0A6P7YP74
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

1415580:SLC2A11
gene id: 1415580:SLC2A11
uniprot id: A0A6P7ZD71
uniprot id: A0A6P7ZM39
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

1415580:GNPNAT1
gene id: 1415580:GNPNAT1
uniprot id: A0A6P7XPH0
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. GNA1 subfamily.
messages: Homodimer.

1415580:TSGA10IP
gene id: 1415580:TSGA10IP
uniprot id: A0A6P7Z9K6
names: Similarity
messages: Belongs to the FAM161 family.

1415580:TRAPPC5
gene id: 1415580:TRAPPC5
uniprot id: A0A6P7XBS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.
messages: cis-Golgi network

1415580:LOC115458198
gene id: 1415580:LOC115458198
uniprot id: A0A6P7WU34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115457370
gene id: 1415580:LOC115457370
uniprot id: A0A6P7WQJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:MAML2
gene id: 1415580:MAML2
uniprot id: A0A6P7XKZ9
uniprot id: A0A6P7XU90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

1415580:STAM2
gene id: 1415580:STAM2
uniprot id: A0A6P7YJV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Early endosome membrane

1415580:LOC115475501
gene id: 1415580:LOC115475501
uniprot id: A0A6P7YI37
names: Similarity
messages: Belongs to the protein kinase superfamily.

1415580:SCRN3
gene id: 1415580:SCRN3
uniprot id: A0A6P7YP30
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

1415580:LOC115475594
gene id: 1415580:LOC115475594
uniprot id: A0A6P7YIM2
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.

1415580:HSPG2
gene id: 1415580:HSPG2
uniprot id: A0A6P7ZFB4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

1415580:RPL32
gene id: 1415580:RPL32
uniprot id: A0A6P7Y135
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

1415580:PPP1R3B
gene id: 1415580:PPP1R3B
uniprot id: A0A6P7X411
uniprot id: A0A6P7XAK8
names: Subunit
messages: Interacts with glycogen, PPP1CC catalytic subunit of PP1 and PYGL. Associates with glycogen particles. Forms complexes with debranching enzyme, glycogen phosphorylase, glycogen synthase and phosphorylase kinase which is necessary for its regulation of PP1 activity.

1415580:PSMA8
gene id: 1415580:PSMA8
uniprot id: A0A6P7YQJ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

1415580:GPX7
gene id: 1415580:GPX7
uniprot id: A0A6P7YGB0
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1415580:BRS3
gene id: 1415580:BRS3
uniprot id: A0A6P7YRH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115462022
gene id: 1415580:LOC115462022
uniprot id: A0A6P7XBI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

1415580:LOC115466383
gene id: 1415580:LOC115466383
uniprot id: A0A6P7XLP2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:AGT
gene id: 1415580:AGT
uniprot id: A0A6P7XGJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serpin family.
messages: Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis.
messages: Secreted
messages: Stimulates aldosterone release.

1415580:EHD2
gene id: 1415580:EHD2
uniprot id: A0A6P7ZCX4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

1415580:NRG3
gene id: 1415580:NRG3
uniprot id: A0A6P7Y1Y4
uniprot id: A0A6P7Y7N8
uniprot id: A0A6P7Y8L0
names: Caution
names: Similarity
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:SMAD2
gene id: 1415580:SMAD2
uniprot id: A0A6P7WZS8
uniprot id: A0A6P7X653
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

1415580:AKAP12
gene id: 1415580:AKAP12
uniprot id: A0A6P7XP74
uniprot id: A0A6P7XV37
names: Subcellular Location Annotation
messages: Membrane

1415580:MMS22L
gene id: 1415580:MMS22L
uniprot id: A0A6P7XUC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MMS22 family. MMS22L subfamily.
messages: Chromosome
messages: Nucleus

1415580:PLA2G15
gene id: 1415580:PLA2G15
uniprot id: A0A6P7YD74
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

1415580:LOC115481045
gene id: 1415580:LOC115481045
uniprot id: A0A6P7ZJ33
names: Similarity
messages: Belongs to the Toll-like receptor family.

1415580:SLC66A2
gene id: 1415580:SLC66A2
uniprot id: A0A6P7YS72
uniprot id: A0A6P7YT07
uniprot id: A0A6P7YT09
uniprot id: A0A6P7YWZ9
names: Subcellular Location Annotation
messages: Membrane

1415580:MALRD1
gene id: 1415580:MALRD1
uniprot id: A0A6P7XZ88
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115477907
gene id: 1415580:LOC115477907
uniprot id: A0A6P7YUQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

1415580:STARD9
gene id: 1415580:STARD9
uniprot id: A0A6P7YYD8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

1415580:CNOT11
gene id: 1415580:CNOT11
uniprot id: A0A6P7XPL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT11 family.
messages: Cytoplasm
messages: Nucleus

1415580:RET
gene id: 1415580:RET
uniprot id: A0A6P7YDE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane
messages: Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.

1415580:CREBL2
gene id: 1415580:CREBL2
uniprot id: A0A6P7YTS6
uniprot id: A0A6P7Z1G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Nucleus

1415580:LOC115475945
gene id: 1415580:LOC115475945
uniprot id: A0A6P7YT54
names: Similarity
messages: Belongs to the peptidase S10 family.

1415580:KCNT2
gene id: 1415580:KCNT2
uniprot id: A0A6P7Y3Z3
uniprot id: A0A6P7YBD7
uniprot id: A0A6P7YH61
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:PAN2
gene id: 1415580:PAN2
uniprot id: A0A6P7XAI0
uniprot id: A0A6P7XPH3
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. PAN2 subfamily.
messages: Binds 2 metal cations per subunit in the catalytic exonuclease domain.
messages: Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.
messages: Contains a pseudo-UCH domain. This ubiquitin C-terminal hydrolase (UCH)-like or ubiquitin specific protease (USP)-like domain is predicted to be catalytically inactive because it lacks the active site catalytic triad characteristic of thiol proteases, with residues at the equivalent structural positions that are incompatible with catalysis, and it cannot bind ubiquitin. It functions as a structural scaffold for intra- and intermolecular interactions in the complex.
messages: Forms a heterotrimer with an asymmetric homodimer of the regulatory subunit PAN3 to form the poly(A)-nuclease (PAN) deadenylation complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: P-body
messages: Positively regulated by the regulatory subunit PAN3.
messages: The linker, or PAN3 interaction domain (PID), between the WD40 repeats and the pseudo-UCH domain mediates interaction with PAN3.

1415580:PARP8
gene id: 1415580:PARP8
uniprot id: A0A6P7XEB5
uniprot id: A0A6P7XFH0
names: Similarity
messages: Belongs to the ARTD/PARP family.

1415580:LOC115457632
gene id: 1415580:LOC115457632
uniprot id: A0A6P7WI74
uniprot id: A0A6P7WPJ2
uniprot id: A0A6P7WRJ0
uniprot id: A0A6P7WYJ3
names: Subcellular Location Annotation
messages: Nucleus

1415580:SLC11A2
gene id: 1415580:SLC11A2
uniprot id: A0A6P7XLT4
uniprot id: A0A6P7XNM1
uniprot id: A0A6P7XUL1
names: Similarity
messages: Belongs to the NRAMP family.

1415580:PSMB8
gene id: 1415580:PSMB8
uniprot id: A0A6P7X6E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

1415580:CAV3
gene id: 1415580:CAV3
uniprot id: A0A6P7XBS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola
messages: sarcolemma

1415580:NOX4
gene id: 1415580:NOX4
uniprot id: A0A6P7XKT3
names: Subcellular Location Annotation
messages: Membrane

1415580:CLTA
gene id: 1415580:CLTA
uniprot id: A0A6P7XCG4
uniprot id: A0A6P7XIW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

1415580:LOC115458221
gene id: 1415580:LOC115458221
uniprot id: A0A6P7WKS5
names: Subcellular Location Annotation
messages: Membrane

1415580:CMPK1
gene id: 1415580:CMPK1
uniprot id: A0A6P7Y9M7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

1415580:LOC115462880
gene id: 1415580:LOC115462880
uniprot id: A0A6P7XDW1
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115461311
gene id: 1415580:LOC115461311
uniprot id: A0A6P7X8L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:KPNA2
gene id: 1415580:KPNA2
uniprot id: A0A6P7YMD2
names: Similarity
messages: Belongs to the importin alpha family.

1415580:DNAJA2
gene id: 1415580:DNAJA2
uniprot id: A0A6P7YBP0
names: Subcellular Location Annotation
messages: Membrane

1415580:TMEM35A
gene id: 1415580:TMEM35A
uniprot id: A0A6P7YKU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane
messages: Vesicle

1415580:SLC43A1
gene id: 1415580:SLC43A1
uniprot id: A0A6P7WM60
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115470372
gene id: 1415580:LOC115470372
uniprot id: A0A6P7Y8C2
names: Caution
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:PDLIM3
gene id: 1415580:PDLIM3
uniprot id: A0A6P7X9U2
uniprot id: A0A6P7XB45
names: Subcellular Location Annotation
messages: Z line

1415580:C3
gene id: 1415580:C3
uniprot id: A0A6P7XHQ8
names: Subcellular Location Annotation
messages: Secreted

1415580:LOC115466908
gene id: 1415580:LOC115466908
uniprot id: A0A6P7XMF9
names: Similarity
messages: Belongs to the TPD52 family.

1415580:ENTPD3
gene id: 1415580:ENTPD3
uniprot id: A0A6P7X064
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

1415580:LOC115458315
gene id: 1415580:LOC115458315
uniprot id: A0A6P7WL76
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115478506
gene id: 1415580:LOC115478506
uniprot id: A0A6P7Z7Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.
messages: Cytoplasm

1415580:TWF1
gene id: 1415580:TWF1
uniprot id: A0A6P7Z3U0
uniprot id: A0A6P7Z9G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

1415580:KAT6B
gene id: 1415580:KAT6B
uniprot id: A0A6P7Y2L2
uniprot id: A0A6P7Y7I1
uniprot id: A0A6P7Y8F4
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

1415580:AKAP8
gene id: 1415580:AKAP8
uniprot id: A0A6P7XBT5
names: Similarity
messages: Belongs to the AKAP95 family.

1415580:MYB
gene id: 1415580:MYB
uniprot id: A0A6P7XUG8
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115475118
gene id: 1415580:LOC115475118
uniprot id: A0A6P7YTX0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:HOXB8
gene id: 1415580:HOXB8
uniprot id: A0A6P7ZCG1
uniprot id: A0A6P7ZGJ8
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115474670
gene id: 1415580:LOC115474670
uniprot id: A0A6P7X3M3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LOC115460552
gene id: 1415580:LOC115460552
uniprot id: A0A6P7X6G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic cobalamin transport proteins family.
messages: Secreted

1415580:LOC115458021
gene id: 1415580:LOC115458021
uniprot id: A0A6P7WR66
uniprot id: A0A6P7WTA3
uniprot id: A0A6P7WZF6
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

1415580:FZD9
gene id: 1415580:FZD9
uniprot id: A0A6P7WEU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Membrane

1415580:LOC115461169
gene id: 1415580:LOC115461169
uniprot id: A0A6P7WU12
names: Similarity
messages: Belongs to the cytochrome P450 family.

1415580:LOC115472560
gene id: 1415580:LOC115472560
uniprot id: A0A6P7Y5B3
names: Subcellular Location Annotation
messages: Membrane

1415580:HDAC3
gene id: 1415580:HDAC3
uniprot id: A0A6P7YVL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

1415580:CAMK1
gene id: 1415580:CAMK1
uniprot id: A0A6P7YLP7
names: Similarity
messages: Belongs to the protein kinase superfamily.

1415580:DIAPH3
gene id: 1415580:DIAPH3
uniprot id: A0A6P7XM57
uniprot id: A0A6P7XTU5
uniprot id: A0A6P7XV85
uniprot id: A0A6P7Y0T3
uniprot id: A0A6P7Y0T7
names: Similarity
messages: Belongs to the formin homology family. Diaphanous subfamily.

1415580:LOC115463657
gene id: 1415580:LOC115463657
uniprot id: A0A6P7XHS8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1415580:CTSL
gene id: 1415580:CTSL
uniprot id: A0A6P7XH00
names: Similarity
messages: Belongs to the peptidase C1 family.

1415580:LOC115464652
gene id: 1415580:LOC115464652
uniprot id: A0A6P7X5J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115457137
gene id: 1415580:LOC115457137
uniprot id: A0A6P7WMV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:PLCB3
gene id: 1415580:PLCB3
uniprot id: A0A6P7ZD72
names: Function
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

1415580:SEMA3D
gene id: 1415580:SEMA3D
uniprot id: A0A6P7Z9T5
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:FOXR1
gene id: 1415580:FOXR1
uniprot id: A0A6P7ZUZ4
uniprot id: A0A6P7ZVQ5
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115470655
gene id: 1415580:LOC115470655
uniprot id: A0A6P7Y4N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX17 family.
messages: Mitochondrion intermembrane space

1415580:SLC31A2
gene id: 1415580:SLC31A2
uniprot id: A0A6P7YDF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

1415580:MAL
gene id: 1415580:MAL
uniprot id: A0A6P7X889
uniprot id: A0A6P7XH42
names: Subcellular Location Annotation
messages: Membrane

1415580:GALR2
gene id: 1415580:GALR2
uniprot id: A0A6P7Y3S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

1415580:LOC115472167
gene id: 1415580:LOC115472167
uniprot id: A0A6P7Y3T9
uniprot id: A0A6P7YAV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

1415580:HTR1D
gene id: 1415580:HTR1D
uniprot id: A0A6P7ZK51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:GPR39
gene id: 1415580:GPR39
uniprot id: A0A6P7YEH1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:GAR1
gene id: 1415580:GAR1
uniprot id: A0A6P7WU29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GAR1 family.
messages: Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).
messages: Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
messages: nucleolus

1415580:GRHL2
gene id: 1415580:GRHL2
uniprot id: A0A6P7Z1S3
names: Subcellular Location Annotation
messages: Nucleus

1415580:POLR2H
gene id: 1415580:POLR2H
uniprot id: A0A6P7YXU0
names: Function
names: Similarity
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.

1415580:LOC115471611
gene id: 1415580:LOC115471611
uniprot id: A0A6P7Y867
uniprot id: A0A6P7YEC6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S9C family.
messages: Cytoplasm
messages: Homotetramer.

1415580:NMUR1
gene id: 1415580:NMUR1
uniprot id: A0A6P7ZAT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

1415580:CLSPN
gene id: 1415580:CLSPN
uniprot id: A0A6P7ZC61
uniprot id: A0A6P7ZJJ3
names: Subcellular Location Annotation
messages: Nucleus

1415580:RTN4IP1
gene id: 1415580:RTN4IP1
uniprot id: A0A6P7XX46
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1415580:NMT1
gene id: 1415580:NMT1
uniprot id: A0A6P7ZAZ8
uniprot id: A0A6P7ZN20
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

1415580:SF3B6
gene id: 1415580:SF3B6
uniprot id: A0A6P7XM64
names: Subcellular Location Annotation
messages: Nucleus

1415580:ATP6V1G2
gene id: 1415580:ATP6V1G2
uniprot id: A0A6P7XFE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

1415580:LOC115469695
gene id: 1415580:LOC115469695
uniprot id: A0A6P7XZM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

1415580:ETFDH
gene id: 1415580:ETFDH
uniprot id: A0A6P7X4S4
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1415580:LOC115463444
gene id: 1415580:LOC115463444
uniprot id: A0A6P7XHQ4
names: Similarity
messages: Belongs to the NLRP family.

1415580:XPA
gene id: 1415580:XPA
uniprot id: A0A6P7XJ66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPA family.
messages: Nucleus

1415580:DDX58
gene id: 1415580:DDX58
uniprot id: A0A6P7XAS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

1415580:LOC115464524
gene id: 1415580:LOC115464524
uniprot id: A0A6P7XDZ8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:MIGA2
gene id: 1415580:MIGA2
uniprot id: A0A6P7YFN2
uniprot id: A0A6P7YKV6
uniprot id: A0A6P7YL40
names: Similarity
messages: Belongs to the mitoguardin family.

1415580:MECOM
gene id: 1415580:MECOM
uniprot id: A0A6P7YXY8
uniprot id: A0A6P7Z3N2
names: Subcellular Location Annotation
messages: Nucleus

1415580:KRT222
gene id: 1415580:KRT222
uniprot id: A0A6P7ZSU1
names: Similarity
messages: Belongs to the intermediate filament family.

1415580:EBF1
gene id: 1415580:EBF1
uniprot id: A0A6P7YJV5
uniprot id: A0A6P7YS14
uniprot id: A0A6P7YSU4
uniprot id: A0A6P7YWS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

1415580:FAM13B
gene id: 1415580:FAM13B
uniprot id: A0A6P7YR46
names: Similarity
messages: Belongs to the FAM13 family.

1415580:PROM1
gene id: 1415580:PROM1
uniprot id: A0A6P7WV78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prominin family.
messages: Membrane
messages: microvillus membrane

1415580:OTUD7B
gene id: 1415580:OTUD7B
uniprot id: A0A6P7WY10
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

1415580:LOC115464924
gene id: 1415580:LOC115464924
uniprot id: A0A6P7XKI7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

1415580:SERPIND1
gene id: 1415580:SERPIND1
uniprot id: A0A6P7ZGH1
names: Similarity
messages: Belongs to the serpin family.

1415580:SUGP2
gene id: 1415580:SUGP2
uniprot id: A0A6P7ZNH6
uniprot id: A0A6P7ZQB7
names: Subcellular Location Annotation
messages: Nucleus

1415580:TASP1
gene id: 1415580:TASP1
uniprot id: A0A6P7XG88
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

1415580:LSM8
gene id: 1415580:LSM8
uniprot id: A0A6P7Z8H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.

1415580:LOC115460610
gene id: 1415580:LOC115460610
uniprot id: A0A6P7X180
uniprot id: A0A6P7X7Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DUOXA family.
messages: Membrane

1415580:LPIN2
gene id: 1415580:LPIN2
uniprot id: A0A6P7YZL6
names: Similarity
messages: Belongs to the lipin family.

1415580:LOC115457724
gene id: 1415580:LOC115457724
uniprot id: A0A6P7WRY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:TOM1L1
gene id: 1415580:TOM1L1
uniprot id: A0A6P7Y9S8
uniprot id: A0A6P7YME5
names: Similarity
messages: Belongs to the TOM1 family.

1415580:ME1
gene id: 1415580:ME1
uniprot id: A0A6P7XCS3
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1415580:LOC115461881
gene id: 1415580:LOC115461881
uniprot id: A0A6P7X340
names: Similarity
messages: Belongs to the MS4A family.

1415580:SERP1
gene id: 1415580:SERP1
uniprot id: A0A6P7Z5X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.
messages: Membrane

1415580:LOC115459797
gene id: 1415580:LOC115459797
uniprot id: A0A6P7WQG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

1415580:EN2
gene id: 1415580:EN2
uniprot id: A0A6P7WXA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Engrailed homeobox family.
messages: Nucleus

1415580:LOC115481059
gene id: 1415580:LOC115481059
uniprot id: A0A6P7ZJ47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

1415580:STARD5
gene id: 1415580:STARD5
uniprot id: A0A6P7WWG8
names: Function
messages: May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols.

1415580:LOC115457252
gene id: 1415580:LOC115457252
uniprot id: A0A6P7WX89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115469301
gene id: 1415580:LOC115469301
uniprot id: A0A6P7XYL5
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

1415580:LOC115467288
gene id: 1415580:LOC115467288
uniprot id: A0A6P7XHM0
uniprot id: A0A6P7XPC0
uniprot id: A0A6P7XR48
uniprot id: A0A6P7XWA4
names: Similarity
messages: Belongs to the sorting nexin family.

1415580:KIF3A
gene id: 1415580:KIF3A
uniprot id: A0A6P7YR58
uniprot id: A0A6P7YVV0
uniprot id: A0A6P7YW05
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

1415580:TFCP2L1
gene id: 1415580:TFCP2L1
uniprot id: A0A6P7YKF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

1415580:ST6GAL1
gene id: 1415580:ST6GAL1
uniprot id: A0A6P7Z2Q7
uniprot id: A0A6P7Z877
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

1415580:LOC115480130
gene id: 1415580:LOC115480130
uniprot id: A0A6P7X5J9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1415580:ALDH3B1
gene id: 1415580:ALDH3B1
uniprot id: A0A6P7ZXF9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1415580:MNX1
gene id: 1415580:MNX1
uniprot id: A0A6P7X6J6
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115479650
gene id: 1415580:LOC115479650
uniprot id: A0A6P7Z7U2
names: Similarity
messages: Belongs to the ARTD/PARP family.

1415580:ZNF592
gene id: 1415580:ZNF592
uniprot id: A0A6P7WIE5
uniprot id: A0A6P7WXT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: May be involved in transcriptional regulation.
messages: Nucleus

1415580:HNRNPH1
gene id: 1415580:HNRNPH1
uniprot id: A0A6P7YWN1
uniprot id: A0A6P7Z0I1
names: Subcellular Location Annotation
messages: nucleoplasm

1415580:CAMK2N1
gene id: 1415580:CAMK2N1
uniprot id: A0A6P8A0S9
names: Similarity
messages: Belongs to the CAMK2N family.

1415580:AVPI1
gene id: 1415580:AVPI1
uniprot id: A0A6P7Y1Q2
names: Function
messages: May be involved in MAP kinase activation, epithelial sodium channel (ENaC) down-regulation and cell cycling.

1415580:PBX1
gene id: 1415580:PBX1
uniprot id: A0A6P7Y2Q4
uniprot id: A0A6P7Y9U4
uniprot id: A0A6P7YFC2
uniprot id: A0A6P7YFZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

1415580:LOC115467868
gene id: 1415580:LOC115467868
uniprot id: A0A6P7XRV6
names: Similarity
messages: Belongs to the peptidase M10A family.

1415580:MICAL1
gene id: 1415580:MICAL1
uniprot id: A0A6P7ZQJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Cytoplasm

1415580:LOC115472368
gene id: 1415580:LOC115472368
uniprot id: A0A6P7YBQ9
uniprot id: A0A6P7YHF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TTC30/dfy-1/fleer family.
messages: Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip.
messages: cilium

1415580:EVC2
gene id: 1415580:EVC2
uniprot id: A0A6P7WV43
uniprot id: A0A6P7X3K9
names: Subcellular Location Annotation
messages: Membrane
messages: cilium basal body
messages: cilium membrane

1415580:ATP11A
gene id: 1415580:ATP11A
uniprot id: A0A6P7XPW7
uniprot id: A0A6P7XWP8
uniprot id: A0A6P7XXW1
uniprot id: A0A6P7Y3G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

1415580:LOC115464996
gene id: 1415580:LOC115464996
uniprot id: A0A6P7XDE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:RNF167
gene id: 1415580:RNF167
uniprot id: A0A6P7WI77
names: Subcellular Location Annotation
messages: Membrane

1415580:MBD4
gene id: 1415580:MBD4
uniprot id: A0A6P7YDL0
uniprot id: A0A6P7YDV3
names: Subcellular Location Annotation
messages: Nucleus

1415580:COQ2
gene id: 1415580:COQ2
uniprot id: A0A6P7XDT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
messages: Mitochondrion inner membrane

1415580:LOC115462125
gene id: 1415580:LOC115462125
uniprot id: A0A6P7XCY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115481768
gene id: 1415580:LOC115481768
uniprot id: A0A6P7ZU66
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.

1415580:WIPI2
gene id: 1415580:WIPI2
uniprot id: A0A6P7YJR3
uniprot id: A0A6P7YSQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PROPPIN family.
messages: Preautophagosomal structure membrane

1415580:RPL10A
gene id: 1415580:RPL10A
uniprot id: A0A6P7ZTP8
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

1415580:ELAVL4
gene id: 1415580:ELAVL4
uniprot id: A0A6P7YF23
names: Similarity
messages: Belongs to the RRM elav family.

1415580:LOC115460537
gene id: 1415580:LOC115460537
uniprot id: A0A6P7X106
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115461745
gene id: 1415580:LOC115461745
uniprot id: A0A6P7WWS4
uniprot id: A0A6P7X2N6
uniprot id: A0A6P7X588
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm

1415580:LOC115464475
gene id: 1415580:LOC115464475
uniprot id: A0A6P7XBP0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LOC115480648
gene id: 1415580:LOC115480648
uniprot id: A0A6P7X5J9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1415580:MYBBP1A
gene id: 1415580:MYBBP1A
uniprot id: A0A6P7ZWN1
names: Similarity
messages: Belongs to the MYBBP1A family.

1415580:LOC115465718
gene id: 1415580:LOC115465718
uniprot id: A0A6P7XGF4
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

1415580:LOC115461953
gene id: 1415580:LOC115461953
uniprot id: A0A6P7XCI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115477050
gene id: 1415580:LOC115477050
uniprot id: A0A6P7Z174
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115467387
gene id: 1415580:LOC115467387
uniprot id: A0A6P7XXD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

1415580:LOC115462390
gene id: 1415580:LOC115462390
uniprot id: A0A6P7X750
names: Similarity
messages: Belongs to the TAFA family.

1415580:LOC115481378
gene id: 1415580:LOC115481378
uniprot id: A0A6P7ZLX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion.
messages: Secreted

1415580:FBXO34
gene id: 1415580:FBXO34
uniprot id: A0A6P7YZV0
names: Function
messages: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

1415580:CHST8
gene id: 1415580:CHST8
uniprot id: A0A6P7XY13
uniprot id: A0A6P7Y5M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

1415580:ATP8B4
gene id: 1415580:ATP8B4
uniprot id: A0A6P7X5M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

1415580:TMEM8A
gene id: 1415580:TMEM8A
uniprot id: A0A6P7YVG2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:CLPP
gene id: 1415580:CLPP
uniprot id: A0A6P7XJW7
uniprot id: A0A6P7XQT9
names: Similarity
messages: Belongs to the peptidase S14 family.

1415580:LOC115474684
gene id: 1415580:LOC115474684
uniprot id: A0A6P7YMA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May be involved in iron transport and iron homeostasis.
messages: Membrane

1415580:VPS25
gene id: 1415580:VPS25
uniprot id: A0A6P7ZRD3
names: Similarity
messages: Belongs to the VPS25 family.

1415580:TMEM102
gene id: 1415580:TMEM102
uniprot id: A0A6P7WWZ3
names: Similarity
messages: Belongs to the mab-21 family.

1415580:COLGALT2
gene id: 1415580:COLGALT2
uniprot id: A0A6P7Y896
uniprot id: A0A6P7YEG2
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

1415580:LOC115476753
gene id: 1415580:LOC115476753
uniprot id: A0A6P7YXB8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1415580:TBXAS1
gene id: 1415580:TBXAS1
uniprot id: A0A6P7YRE0
uniprot id: A0A6P7Z2V9
names: Similarity
messages: Belongs to the cytochrome P450 family.

1415580:L3MBTL1
gene id: 1415580:L3MBTL1
uniprot id: A0A6P7YUR1
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115472459
gene id: 1415580:LOC115472459
uniprot id: A0A6P7YI70
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

1415580:TMEM161A
gene id: 1415580:TMEM161A
uniprot id: A0A6P7ZJY8
uniprot id: A0A6P7ZQW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM161 family.
messages: Membrane

1415580:LOC115471078
gene id: 1415580:LOC115471078
uniprot id: A0A6P7XZ12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

1415580:VWA2
gene id: 1415580:VWA2
uniprot id: A0A6P7XSZ4
uniprot id: A0A6P7Y142
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:PPM1G
gene id: 1415580:PPM1G
uniprot id: A0A6P7XUW0
names: Similarity
messages: Belongs to the PP2C family.

1415580:PPARD
gene id: 1415580:PPARD
uniprot id: A0A6P7ZFE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

1415580:ASXL1
gene id: 1415580:ASXL1
uniprot id: A0A6P7YQY5
uniprot id: A0A6P7YV28
uniprot id: A0A6P7YV45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Asx family.
messages: Nucleus

1415580:SNX30
gene id: 1415580:SNX30
uniprot id: A0A6P7XG51
names: Similarity
messages: Belongs to the sorting nexin family.

1415580:VWC2
gene id: 1415580:VWC2
uniprot id: A0A6P7YQ31
names: Subcellular Location Annotation
messages: Synapse

1415580:SNX11
gene id: 1415580:SNX11
uniprot id: A0A6P7ZAM2
uniprot id: A0A6P7ZM69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

1415580:SUOX
gene id: 1415580:SUOX
uniprot id: A0A6P7XAJ1
uniprot id: A0A6P7XQC3
names: Function
messages: Catalyzes the oxidation of sulfite to sulfate, the terminal reaction in the oxidative degradation of sulfur-containing amino acids.

1415580:LOC115469234
gene id: 1415580:LOC115469234
uniprot id: A0A6P7Y3D5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1415580:HPGD
gene id: 1415580:HPGD
uniprot id: A0A6P7X210
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1415580:RBFOX1
gene id: 1415580:RBFOX1
uniprot id: A0A6P7YV31
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

1415580:LOC115462023
gene id: 1415580:LOC115462023
uniprot id: A0A6P7X3H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

1415580:SMARCAL1
gene id: 1415580:SMARCAL1
uniprot id: A0A6P7YDL4
uniprot id: A0A6P7YR02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.
messages: Nucleus

1415580:TRIM3
gene id: 1415580:TRIM3
uniprot id: A0A6P7XY30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIM/RBCC family.
messages: Cytoplasm

1415580:SMUG1
gene id: 1415580:SMUG1
uniprot id: A0A6P7XU52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. SMUG1 family.
messages: Nucleus

1415580:ZDHHC7
gene id: 1415580:ZDHHC7
uniprot id: A0A6P7Y616
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

1415580:PNP
gene id: 1415580:PNP
uniprot id: A0A6P7WZX7
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1415580:LOC115471994
gene id: 1415580:LOC115471994
uniprot id: A0A6P7YFK1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

1415580:DDX39A
gene id: 1415580:DDX39A
uniprot id: A0A6P7XBP7
names: Subcellular Location Annotation
messages: Cytoplasm

1415580:SATB1
gene id: 1415580:SATB1
uniprot id: A0A6P7XSW9
uniprot id: A0A6P7XSY7
uniprot id: A0A6P7Y087
uniprot id: A0A6P7Y153
uniprot id: A0A6P7Y609
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

1415580:LOC115480176
gene id: 1415580:LOC115480176
uniprot id: A0A6P7ZG16
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:MSH6
gene id: 1415580:MSH6
uniprot id: A0A6P7XLY7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).

1415580:LOC115479415
gene id: 1415580:LOC115479415
uniprot id: A0A6P7ZBU9
names: Similarity
messages: Belongs to the histone H3 family.

1415580:LOC115478627
gene id: 1415580:LOC115478627
uniprot id: A0A6P7YXW5
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

1415580:LOC115461227
gene id: 1415580:LOC115461227
uniprot id: A0A6P7X9J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:C2H4orf48
gene id: 1415580:C2H4orf48
uniprot id: A0A6P7X552
names: Subcellular Location Annotation
messages: Secreted

1415580:BAK1
gene id: 1415580:BAK1
uniprot id: A0A6P7ZCL3
names: Similarity
messages: Belongs to the Bcl-2 family.

1415580:RPE65
gene id: 1415580:RPE65
uniprot id: A0A6P7YH92
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

1415580:LOC115468752
gene id: 1415580:LOC115468752
uniprot id: A0A6P7XMI9
names: Cofactor
names: Similarity
messages: Belongs to the paraoxonase family.
messages: Binds 2 calcium ions per subunit.

1415580:RTN1
gene id: 1415580:RTN1
uniprot id: A0A6P7YR38
uniprot id: A0A6P7YXS0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:TRAPPC3L
gene id: 1415580:TRAPPC3L
uniprot id: A0A6P7XHX5
uniprot id: A0A6P7XX97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

1415580:MAML3
gene id: 1415580:MAML3
uniprot id: A0A6P7XBQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

1415580:C7
gene id: 1415580:C7
uniprot id: A0A6P7X086
uniprot id: A0A6P7X6M1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

1415580:NPM3
gene id: 1415580:NPM3
uniprot id: A0A6P7Y6N9
names: Similarity
messages: Belongs to the nucleoplasmin family.

1415580:LOC115480300
gene id: 1415580:LOC115480300
uniprot id: A0A6P7ZGP0
names: Similarity
messages: Belongs to the EVA1 family.

1415580:CSTF2
gene id: 1415580:CSTF2
uniprot id: A0A6P7YE69
uniprot id: A0A6P7YL63
uniprot id: A0A6P7YLS4
uniprot id: A0A6P7YR79
uniprot id: A0A6P7YRE7
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115464632
gene id: 1415580:LOC115464632
uniprot id: A0A6P7XJR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1415580:PCLO
gene id: 1415580:PCLO
uniprot id: A0A6P7Z542
names: Subcellular Location Annotation
messages: Presynaptic active zone

1415580:OPRL1
gene id: 1415580:OPRL1
uniprot id: A0A6P7YM68
uniprot id: A0A6P7YUY6
uniprot id: A0A6P7YYU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.
messages: Membrane
messages: Vesicle

1415580:MARK1
gene id: 1415580:MARK1
uniprot id: A0A6P7X8F6
uniprot id: A0A6P7XF94
uniprot id: A0A6P7XHE1
uniprot id: A0A6P7XHE5
uniprot id: A0A6P7XMG6
uniprot id: A0A6P7XN87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

1415580:EFHC2
gene id: 1415580:EFHC2
uniprot id: A0A6P7XJ87
uniprot id: A0A6P7XR43
names: Subcellular Location Annotation
messages: cilium axoneme

1415580:LOC115476669
gene id: 1415580:LOC115476669
uniprot id: A0A6P7YZW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:GPR61
gene id: 1415580:GPR61
uniprot id: A0A6P7ZEJ2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:MTMR12
gene id: 1415580:MTMR12
uniprot id: A0A6P7X005
uniprot id: A0A6P7X8Q0
uniprot id: A0A6P7XF75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Sarcoplasmic reticulum
messages: sarcomere

1415580:CPZ
gene id: 1415580:CPZ
uniprot id: A0A6P7X8X4
names: Caution
names: Similarity
messages: Belongs to the peptidase M14 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115471271
gene id: 1415580:LOC115471271
uniprot id: A0A6P7Y782
names: Similarity
messages: Belongs to the hexokinase family.

1415580:LOC115480644
gene id: 1415580:LOC115480644
uniprot id: A0A6P7ZM92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

1415580:LIX1L
gene id: 1415580:LIX1L
uniprot id: A0A6P7WYP3
names: Similarity
messages: Belongs to the LIX1 family.

1415580:MGAT2
gene id: 1415580:MGAT2
uniprot id: A0A6P7Z6Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 16 (GT16) protein family.
messages: Golgi apparatus membrane
messages: Membrane

1415580:LOC115461248
gene id: 1415580:LOC115461248
uniprot id: A0A6P7X8B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin 150 kDa subunit family.
messages: cell cortex
messages: cytoskeleton

1415580:TMEM255A
gene id: 1415580:TMEM255A
uniprot id: A0A6P7YK47
uniprot id: A0A6P7YPZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM255 family.
messages: Membrane

1415580:LOC115456941
gene id: 1415580:LOC115456941
uniprot id: A0A6P7WV75
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

1415580:PMS2
gene id: 1415580:PMS2
uniprot id: A0A6P7YZY0
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

1415580:LOC115472516
gene id: 1415580:LOC115472516
uniprot id: A0A6P7YI01
names: Similarity
messages: Belongs to the PRKRIP1 family.

1415580:LBX1
gene id: 1415580:LBX1
uniprot id: A0A6P7Y6U0
names: Subcellular Location Annotation
messages: Nucleus

1415580:EFNB1
gene id: 1415580:EFNB1
uniprot id: A0A6P7YNL9
names: Caution
names: Similarity
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:STOML1
gene id: 1415580:STOML1
uniprot id: A0A6P7WRG3
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1415580:MLEC
gene id: 1415580:MLEC
uniprot id: A0A6P7ZEN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the malectin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:LOC115456906
gene id: 1415580:LOC115456906
uniprot id: A0A6P7WP55
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

1415580:MYF5
gene id: 1415580:MYF5
uniprot id: A0A6P7Z500
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

1415580:LOC115457257
gene id: 1415580:LOC115457257
uniprot id: A0A6P7WWA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115473577
gene id: 1415580:LOC115473577
uniprot id: A0A6P7YHT8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynurenine formamidase family.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.
messages: Homodimer.
messages: Nucleus
messages: The main chain amide nitrogen atoms of the second glycine and its adjacent residue in the HGGXW motif define the oxyanion hole, and stabilize the oxyanion that forms during the nucleophilic attack by the catalytic serine during substrate cleavage.
messages: cytosol

1415580:LOC115475068
gene id: 1415580:LOC115475068
uniprot id: A0A6P7YNR3
names: Similarity
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.

1415580:LOC115465214
gene id: 1415580:LOC115465214
uniprot id: A0A6P7X7C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:FMO3
gene id: 1415580:FMO3
uniprot id: A0A6P7Y8N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

1415580:LOC115463437
gene id: 1415580:LOC115463437
uniprot id: A0A6P7X2K2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane

1415580:NSMCE4A
gene id: 1415580:NSMCE4A
uniprot id: A0A6P7XSQ5
uniprot id: A0A6P7Y0V2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE4 family.
messages: Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
messages: Component of the SMC5-SMC6 complex.
messages: Nucleus
messages: telomere

1415580:CHM
gene id: 1415580:CHM
uniprot id: A0A6P7YJ13
uniprot id: A0A6P7YNV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.

1415580:DDAH1
gene id: 1415580:DDAH1
uniprot id: A0A6P7YE56
names: Function
names: Similarity
messages: Belongs to the DDAH family.
messages: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.

1415580:CBL
gene id: 1415580:CBL
uniprot id: A0A6P7ZM57
uniprot id: A0A6P7ZSY8
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

1415580:FURIN
gene id: 1415580:FURIN
uniprot id: A0A6P7X4L2
names: Similarity
messages: Belongs to the peptidase S8 family.

1415580:SOX6
gene id: 1415580:SOX6
uniprot id: A0A6P7Y1J7
names: Subcellular Location Annotation
messages: Nucleus

1415580:SMIM18
gene id: 1415580:SMIM18
uniprot id: A0A6P7XI94
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115457114
gene id: 1415580:LOC115457114
uniprot id: A0A6P7WGM3
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115473543
gene id: 1415580:LOC115473543
uniprot id: A0A6P7YAF9
names: Similarity
messages: Belongs to the SNF7 family.

1415580:LOC115464447
gene id: 1415580:LOC115464447
uniprot id: A0A6P7XBL2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LOC115457228
gene id: 1415580:LOC115457228
uniprot id: A0A6P7WQ61
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115464518
gene id: 1415580:LOC115464518
uniprot id: A0A6P7XDZ3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LSM12
gene id: 1415580:LSM12
uniprot id: A0A6P7ZTC7
names: Similarity
messages: Belongs to the LSM12 family.

1415580:QSOX1
gene id: 1415580:QSOX1
uniprot id: A0A6P7YHS5
names: Function
names: Similarity
messages: Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.
messages: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide.

1415580:USP32
gene id: 1415580:USP32
uniprot id: A0A6P7ZKV5
uniprot id: A0A6P7ZVU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Nucleus

1415580:LOC115480967
gene id: 1415580:LOC115480967
uniprot id: A0A6P7Z8Y3
names: Similarity
messages: Belongs to the histone H2B family.
messages: Belongs to the histone H3 family.

1415580:TP53INP1
gene id: 1415580:TP53INP1
uniprot id: A0A6P7Z7P3
uniprot id: A0A6P7ZAF0
names: Subcellular Location Annotation
messages: PML body
messages: autophagosome
messages: cytosol

1415580:LOC115472425
gene id: 1415580:LOC115472425
uniprot id: A0A6P7YC25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

1415580:DEGS1
gene id: 1415580:DEGS1
uniprot id: A0A6P7XHA4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Endoplasmic reticulum membrane
messages: Interacts with RLBP1; the interaction increases synthesis of chromophore-precursors by DEGS1.
messages: Membrane

1415580:MELK
gene id: 1415580:MELK
uniprot id: A0A6P7ZKV1
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

1415580:LOC115472606
gene id: 1415580:LOC115472606
uniprot id: A0A6P7Y5G5
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

1415580:KIF21A
gene id: 1415580:KIF21A
uniprot id: A0A6P7Z108
uniprot id: A0A6P7Z113
uniprot id: A0A6P7Z6C7
uniprot id: A0A6P7Z6D2
uniprot id: A0A6P7Z8W8
uniprot id: A0A6P7ZBJ6
uniprot id: A0A6P7ZBK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

1415580:BLCAP
gene id: 1415580:BLCAP
uniprot id: A0A6P7YVH9
names: Similarity
messages: Belongs to the BLCAP family.

1415580:PICALM
gene id: 1415580:PICALM
uniprot id: A0A6P7XKM5
uniprot id: A0A6P7XSG5
uniprot id: A0A6P7XU08
uniprot id: A0A6P7XU12
uniprot id: A0A6P7XZ15
uniprot id: A0A6P7XZP2
uniprot id: A0A6P7XZP6
names: Similarity
messages: Belongs to the PICALM/SNAP91 family.

1415580:BTD
gene id: 1415580:BTD
uniprot id: A0A6P7X5J7
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

1415580:MKNK1
gene id: 1415580:MKNK1
uniprot id: A0A6P7Y5T0
uniprot id: A0A6P7YCW5
uniprot id: A0A6P7YIZ7
names: Similarity
messages: Belongs to the protein kinase superfamily.

1415580:DACT3
gene id: 1415580:DACT3
uniprot id: A0A6P7ZAG4
names: Similarity
messages: Belongs to the dapper family.

1415580:YAF2
gene id: 1415580:YAF2
uniprot id: A0A6P7YZA6
names: Subcellular Location Annotation
messages: Nucleus

1415580:TBX2
gene id: 1415580:TBX2
uniprot id: A0A6P7WKQ3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

1415580:SPPL2B
gene id: 1415580:SPPL2B
uniprot id: A0A6P7ZDF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Endosome membrane
messages: Lysosome membrane
messages: Membrane

1415580:LOC115457223
gene id: 1415580:LOC115457223
uniprot id: A0A6P7WX66
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115474158
gene id: 1415580:LOC115474158
uniprot id: A0A6P7YKM4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

1415580:LOC115468906
gene id: 1415580:LOC115468906
uniprot id: A0A6P7XNI0
uniprot id: A0A6P7XWK3
uniprot id: A0A6P7Y1I7
uniprot id: A0A6P7Y234
names: Similarity
messages: Belongs to the cytochrome P450 family.

1415580:LOC115462376
gene id: 1415580:LOC115462376
uniprot id: A0A6P7XDJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:TMEM216
gene id: 1415580:TMEM216
uniprot id: A0A6P7XNU0
uniprot id: A0A6P7Y1V3
uniprot id: A0A6P7Y2F1
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115457006
gene id: 1415580:LOC115457006
uniprot id: A0A6P7WGC4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:HVCN1
gene id: 1415580:HVCN1
uniprot id: A0A6P7ZDT5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hydrogen channel family.
messages: Homodimer.
messages: Membrane

1415580:NDUFS4
gene id: 1415580:NDUFS4
uniprot id: A0A6P7X0C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS4 subunit family.
messages: Mitochondrion inner membrane

1415580:NAP1L1
gene id: 1415580:NAP1L1
uniprot id: A0A6P7YS12
uniprot id: A0A6P7YYI3
uniprot id: A0A6P7Z2L4
uniprot id: A0A6P7Z3E6
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

1415580:IGF1
gene id: 1415580:IGF1
uniprot id: A0A6P7YTE9
uniprot id: A0A6P7YZR8
uniprot id: A0A6P7Z3Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

1415580:EYA3
gene id: 1415580:EYA3
uniprot id: A0A6P7ZEA4
uniprot id: A0A6P7ZKG2
uniprot id: A0A6P7ZRA2
uniprot id: A0A6P7ZRB1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

1415580:CALB2
gene id: 1415580:CALB2
uniprot id: A0A6P7YCL3
names: Function
names: Similarity
messages: Belongs to the calbindin family.
messages: Calretinin is a calcium-binding protein which is abundant in auditory neurons.

1415580:FABP6
gene id: 1415580:FABP6
uniprot id: A0A6P7YVR0
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

1415580:FLNB
gene id: 1415580:FLNB
uniprot id: A0A6P7Y0Y0
uniprot id: A0A6P7Y884
uniprot id: A0A6P7Y887
uniprot id: A0A6P7Y8A9
uniprot id: A0A6P7Y8B4
uniprot id: A0A6P7YDR1
uniprot id: A0A6P7YDR7
uniprot id: A0A6P7YEE1
uniprot id: A0A6P7YEE7
names: Similarity
messages: Belongs to the filamin family.

1415580:ITPR3
gene id: 1415580:ITPR3
uniprot id: A0A6P7ZAD8
uniprot id: A0A6P7ZET0
uniprot id: A0A6P7ZLP4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the InsP3 receptor family.
messages: Endoplasmic reticulum membrane
messages: Homotetramer.
messages: Membrane
messages: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
messages: The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.

1415580:LOC115462000
gene id: 1415580:LOC115462000
uniprot id: A0A6P7X605
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115466419
gene id: 1415580:LOC115466419
uniprot id: A0A6P7XJV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Cytoplasm
messages: Nucleus
messages: Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.

1415580:LOC115480807
gene id: 1415580:LOC115480807
uniprot id: A0A6P7ZCY0
uniprot id: A0A6P7ZCY5
uniprot id: A0A6P7ZLG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1415580:TMBIM1
gene id: 1415580:TMBIM1
uniprot id: A0A6P7YJZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1415580:LOC115465237
gene id: 1415580:LOC115465237
uniprot id: A0A6P7XLG2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Interacts with SQSTM1.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

1415580:LOC115474120
gene id: 1415580:LOC115474120
uniprot id: A0A6P7YQC8
names: Similarity
messages: Belongs to the intermediate filament family.

1415580:CHRNB2
gene id: 1415580:CHRNB2
uniprot id: A0A6P7WJ16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

1415580:LOC115462131
gene id: 1415580:LOC115462131
uniprot id: A0A6P7XCY7
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

1415580:DPY19L1
gene id: 1415580:DPY19L1
uniprot id: A0A6P7Y611
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

1415580:CACNB4
gene id: 1415580:CACNB4
uniprot id: A0A6P7YC44
names: Similarity
messages: Belongs to the calcium channel beta subunit family.

1415580:ADD2
gene id: 1415580:ADD2
uniprot id: A0A6P7XQU4
uniprot id: A0A6P7Y3X9
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

1415580:GET3
gene id: 1415580:GET3
uniprot id: A0A6P7XB50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
messages: Belongs to the arsA ATPase family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Homodimer.

1415580:LOC115460373
gene id: 1415580:LOC115460373
uniprot id: A0A6P7WXY4
names: Similarity
messages: Belongs to the cytochrome P450 family.

1415580:LOC115464417
gene id: 1415580:LOC115464417
uniprot id: A0A6P7XK21
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LOC115471424
gene id: 1415580:LOC115471424
uniprot id: A0A6P7Y7P8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

1415580:PWP2
gene id: 1415580:PWP2
uniprot id: A0A6P7XW11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PWP2 family.
messages: nucleolus

1415580:LOC115464683
gene id: 1415580:LOC115464683
uniprot id: A0A6P7XEH9
names: Similarity
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.

1415580:NPEPL1
gene id: 1415580:NPEPL1
uniprot id: A0A6P7YVN1
names: Similarity
messages: Belongs to the peptidase M17 family.

1415580:LOC115470108
gene id: 1415580:LOC115470108
uniprot id: A0A6P7Y235
uniprot id: A0A6P7Y806
names: Similarity
messages: Belongs to the cytochrome P450 family.

1415580:LOC115460495
gene id: 1415580:LOC115460495
uniprot id: A0A6P7WY91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:NAGK
gene id: 1415580:NAGK
uniprot id: A0A6P7X8G4
names: Similarity
messages: Belongs to the eukaryotic-type N-acetylglucosamine kinase family.

1415580:RBKS
gene id: 1415580:RBKS
uniprot id: A0A6P7XEW5
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1415580:BCL7A
gene id: 1415580:BCL7A
uniprot id: A0A6P7Z669
uniprot id: A0A6P7ZB38
names: Similarity
messages: Belongs to the BCL7 family.

1415580:IFIH1
gene id: 1415580:IFIH1
uniprot id: A0A6P7YL09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

1415580:BCL2L13
gene id: 1415580:BCL2L13
uniprot id: A0A6P7Z2M0
names: Similarity
messages: Belongs to the Bcl-2 family.

1415580:CD74
gene id: 1415580:CD74
uniprot id: A0A6P7YU85
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:GPR152
gene id: 1415580:GPR152
uniprot id: A0A6P7X150
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:PARP1
gene id: 1415580:PARP1
uniprot id: A0A6P7XLP4
uniprot id: A0A6P7XMI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Chromosome
messages: Nucleus
messages: Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair.

1415580:NKX2-4
gene id: 1415580:NKX2-4
uniprot id: A0A6P7XFW3
names: Subcellular Location Annotation
messages: Nucleus

1415580:DGAT2
gene id: 1415580:DGAT2
uniprot id: A0A6P7XYT5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:DYNLRB1
gene id: 1415580:DYNLRB1
uniprot id: A0A6P7YR82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
messages: Belongs to the GAMAD family.
messages: cytoskeleton

1415580:LOC115464718
gene id: 1415580:LOC115464718
uniprot id: A0A6P7XKU3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:SLC26A10
gene id: 1415580:SLC26A10
uniprot id: A0A6P7XQ06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1415580:SEZ6L2
gene id: 1415580:SEZ6L2
uniprot id: A0A6P7YGU6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:ABCD3
gene id: 1415580:ABCD3
uniprot id: A0A6P7YHE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.
messages: Membrane
messages: Peroxisome membrane

1415580:LOC115478998
gene id: 1415580:LOC115478998
uniprot id: A0A6P7YZL4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:GPR182
gene id: 1415580:GPR182
uniprot id: A0A6P7XJ84
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:LOC115479965
gene id: 1415580:LOC115479965
uniprot id: A0A6P7Z9E0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

1415580:ZFHX3
gene id: 1415580:ZFHX3
uniprot id: A0A6P7Y6C1
names: Subcellular Location Annotation
messages: Nucleus

1415580:ZFX
gene id: 1415580:ZFX
uniprot id: A0A6P7XZD7
uniprot id: A0A6P7Y552
names: Subcellular Location Annotation
messages: Nucleus

1415580:SLC4A1
gene id: 1415580:SLC4A1
uniprot id: A0A6P7ZSV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

1415580:PLBD1
gene id: 1415580:PLBD1
uniprot id: A0A6P7YD89
uniprot id: A0A6P7YD99
uniprot id: A0A6P7YDK8
names: Function
names: Similarity
messages: Belongs to the phospholipase B-like family.
messages: Putative phospholipase.

1415580:LOC115461063
gene id: 1415580:LOC115461063
uniprot id: A0A6P7X7B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115479693
gene id: 1415580:LOC115479693
uniprot id: A0A6P7ZDJ1
names: Similarity
messages: Belongs to the actin family.

1415580:NPBWR2
gene id: 1415580:NPBWR2
uniprot id: A0A6P7YWH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:CACNB2
gene id: 1415580:CACNB2
uniprot id: A0A6P7XQG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
messages: sarcolemma

1415580:LOC115464237
gene id: 1415580:LOC115464237
uniprot id: A0A6P7X4F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAYP family.
messages: Nucleus

1415580:PAQR4
gene id: 1415580:PAQR4
uniprot id: A0A6P7YKD6
uniprot id: A0A6P7YQB6
uniprot id: A0A6P7YQN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

1415580:PEX5L
gene id: 1415580:PEX5L
uniprot id: A0A6P7YYH5
uniprot id: A0A6P7Z453
uniprot id: A0A6P7Z6E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal targeting signal receptor family.
messages: Cytoplasm
messages: Membrane

1415580:MAGI3
gene id: 1415580:MAGI3
uniprot id: A0A6P7ZK52
uniprot id: A0A6P7ZUX9
uniprot id: A0A6P7ZVM6
uniprot id: A0A6P7ZWP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: Membrane
messages: tight junction

1415580:LOC115457884
gene id: 1415580:LOC115457884
uniprot id: A0A6P7WQK8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

1415580:GJB1
gene id: 1415580:GJB1
uniprot id: A0A6P7YL02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Beta-type (group I) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

1415580:GPNMB
gene id: 1415580:GPNMB
uniprot id: A0A6P7XYM4
names: Similarity
messages: Belongs to the PMEL/NMB family.

1415580:RIMKLB
gene id: 1415580:RIMKLB
uniprot id: A0A6P7WIH6
uniprot id: A0A6P7WRT8
names: Similarity
messages: Belongs to the RimK family.

1415580:CLUAP1
gene id: 1415580:CLUAP1
uniprot id: A0A6P7YNS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLUAP1 family.
messages: cilium

1415580:IFT20
gene id: 1415580:IFT20
uniprot id: A0A6P7WL02
names: Subcellular Location Annotation
messages: centriole
messages: cilium
messages: cis-Golgi network

1415580:NLGN1
gene id: 1415580:NLGN1
uniprot id: A0A6P7Z0E2
uniprot id: A0A6P7Z5T6
uniprot id: A0A6P7Z884
uniprot id: A0A6P7ZAW6
uniprot id: A0A6P7ZAX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

1415580:KCNQ1
gene id: 1415580:KCNQ1
uniprot id: A0A6P7XNQ6
uniprot id: A0A6P7XVI1
uniprot id: A0A6P7XWT3
uniprot id: A0A6P7Y2B7
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the potassium channel family. KQT (TC 1.A.1.15) subfamily. Kv7.1/KCNQ1 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum
messages: Lateral cell membrane
messages: Membrane
messages: Membrane raft

1415580:ESYT1
gene id: 1415580:ESYT1
uniprot id: A0A6P7XHE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the extended synaptotagmin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:HOXA3
gene id: 1415580:HOXA3
uniprot id: A0A6P7Y507
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

1415580:NAP1L4
gene id: 1415580:NAP1L4
uniprot id: A0A6P7Y2B2
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

1415580:GOLM1
gene id: 1415580:GOLM1
uniprot id: A0A6P7X1U9
uniprot id: A0A6P7X8A6
uniprot id: A0A6P7XFV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLM family.
messages: Membrane

1415580:PKD2L2
gene id: 1415580:PKD2L2
uniprot id: A0A6P7YXP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Membrane
messages: cilium membrane

1415580:LOC115466747
gene id: 1415580:LOC115466747
uniprot id: A0A6P7XLK6
names: Similarity
messages: Belongs to the intermediate filament family.

1415580:SLC25A31
gene id: 1415580:SLC25A31
uniprot id: A0A6P7XBU4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

1415580:SAP30L
gene id: 1415580:SAP30L
uniprot id: A0A6P7YW19
names: Similarity
messages: Belongs to the SAP30 family.

1415580:NHEJ1
gene id: 1415580:NHEJ1
uniprot id: A0A6P7YFG3
uniprot id: A0A6P7YN47
uniprot id: A0A6P7YSE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XRCC4-XLF family. XLF subfamily.
messages: Nucleus

1415580:SUSD3
gene id: 1415580:SUSD3
uniprot id: A0A6P7Y779
uniprot id: A0A6P7YEL0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:RNF2
gene id: 1415580:RNF2
uniprot id: A0A6P7YA75
names: Subcellular Location Annotation
messages: Chromosome
messages: Cytoplasm

1415580:USP15
gene id: 1415580:USP15
uniprot id: A0A6P7Z167
uniprot id: A0A6P7Z932
uniprot id: A0A6P7Z939
uniprot id: A0A6P7ZBQ1
uniprot id: A0A6P7ZCK2
uniprot id: A0A6P7ZCK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Nucleus

1415580:MRPL33
gene id: 1415580:MRPL33
uniprot id: A0A6P7XH08
uniprot id: A0A6P7XMW9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1415580:HPSE
gene id: 1415580:HPSE
uniprot id: A0A6P7X7D3
names: Similarity
messages: Belongs to the glycosyl hydrolase 79 family.

1415580:RPL38
gene id: 1415580:RPL38
uniprot id: A0A6P7YHH9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL38 family.

1415580:CDK2
gene id: 1415580:CDK2
uniprot id: A0A6P7XPI4
names: Similarity
messages: Belongs to the protein kinase superfamily.

1415580:FZD1
gene id: 1415580:FZD1
uniprot id: A0A6P7XKR6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:CHAF1B
gene id: 1415580:CHAF1B
uniprot id: A0A6P7XR22
names: Subcellular Location Annotation
messages: Nucleus

1415580:TMEM200A
gene id: 1415580:TMEM200A
uniprot id: A0A6P7X9W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

1415580:LOC115482282
gene id: 1415580:LOC115482282
uniprot id: A0A6P7ZVN5
uniprot id: A0A6P7ZWS6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115470865
gene id: 1415580:LOC115470865
uniprot id: A0A6P7XY38
uniprot id: A0A6P7Y5P9
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1415580:SSU72
gene id: 1415580:SSU72
uniprot id: A0A6P7WG05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSU72 phosphatase family.
messages: Nucleus
messages: Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination.

1415580:LOC115474732
gene id: 1415580:LOC115474732
uniprot id: A0A6P7YSH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

1415580:DNPEP
gene id: 1415580:DNPEP
uniprot id: A0A6P7YFP1
names: Similarity
names: Subunit
messages: Belongs to the peptidase M18 family.
messages: Tetrahedron-shaped homododecamer built from six homodimers.

1415580:IMPA1
gene id: 1415580:IMPA1
uniprot id: A0A6P7Z8Q6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1415580:LOC115462388
gene id: 1415580:LOC115462388
uniprot id: A0A6P7XCD4
names: Subcellular Location Annotation
messages: Membrane

1415580:LANCL2
gene id: 1415580:LANCL2
uniprot id: A0A6P7YDW8
names: Similarity
messages: Belongs to the LanC-like protein family.

1415580:GPAT3
gene id: 1415580:GPAT3
uniprot id: A0A6P7X1R0
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

1415580:DCLK3
gene id: 1415580:DCLK3
uniprot id: A0A6P7YEV1
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

1415580:LOC115457957
gene id: 1415580:LOC115457957
uniprot id: A0A6P7WJP4
uniprot id: A0A6P7WT12
uniprot id: A0A6P7WZ08
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

1415580:LMOD3
gene id: 1415580:LMOD3
uniprot id: A0A6P7YCM8
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

1415580:SEMA3B
gene id: 1415580:SEMA3B
uniprot id: A0A6P7Y2R0
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:CKMT1A
gene id: 1415580:CKMT1A
uniprot id: A0A6P7X4K2
uniprot id: A0A6P7X5T5
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

1415580:DAXX
gene id: 1415580:DAXX
uniprot id: A0A6P7XBW3
uniprot id: A0A6P7XKN5
uniprot id: A0A6P7XRJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAXX family.
messages: Cytoplasm
messages: PML body
messages: centromere
messages: nucleolus
messages: nucleoplasm

1415580:ING5
gene id: 1415580:ING5
uniprot id: A0A6P7Z5X1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

1415580:SUZ12
gene id: 1415580:SUZ12
uniprot id: A0A6P7YH24
uniprot id: A0A6P7YM89
names: Similarity
messages: Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family.

1415580:CDC25A
gene id: 1415580:CDC25A
uniprot id: A0A6P7XA15
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

1415580:EFNA4
gene id: 1415580:EFNA4
uniprot id: A0A6P7WKE1
uniprot id: A0A6P7WTS3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:LOC115469981
gene id: 1415580:LOC115469981
uniprot id: A0A6P7XT97
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

1415580:ARPC3
gene id: 1415580:ARPC3
uniprot id: A0A6P7ZM18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC3 family.
messages: Component of the Arp2/3 complex.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

1415580:MPPE1
gene id: 1415580:MPPE1
uniprot id: A0A6P7YU10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallophosphoesterase superfamily. MPPE1 family.
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins.
messages: cis-Golgi network membrane

1415580:EIF2A
gene id: 1415580:EIF2A
uniprot id: A0A6P7YYN7
names: Function
names: Similarity
messages: Belongs to the WD repeat EIF2A family.
messages: Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.

1415580:LOC115457376
gene id: 1415580:LOC115457376
uniprot id: A0A6P7WWM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115472382
gene id: 1415580:LOC115472382
uniprot id: A0A6P7YHV8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1415580:FGB
gene id: 1415580:FGB
uniprot id: A0A6P7X3Y3
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

1415580:GINS1
gene id: 1415580:GINS1
uniprot id: A0A6P7XI58
uniprot id: A0A6P7XNC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS1/PSF1 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus
messages: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.

1415580:KIF16B
gene id: 1415580:KIF16B
uniprot id: A0A6P7XPB3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

1415580:FAM120C
gene id: 1415580:FAM120C
uniprot id: A0A6P7XIM3
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

1415580:MGST1
gene id: 1415580:MGST1
uniprot id: A0A6P7YUQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Membrane

1415580:TMEM98
gene id: 1415580:TMEM98
uniprot id: A0A6P7ZQL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM98 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: extracellular exosome

1415580:BEST2
gene id: 1415580:BEST2
uniprot id: A0A6P7X6A5
uniprot id: A0A6P7XD15
uniprot id: A0A6P7XKG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bestrophin family.
messages: Cell membrane
messages: Forms chloride channels.
messages: Membrane

1415580:MPP3
gene id: 1415580:MPP3
uniprot id: A0A6P7ZPV7
uniprot id: A0A6P7ZUX0
names: Similarity
messages: Belongs to the MAGUK family.

1415580:HOXA9
gene id: 1415580:HOXA9
uniprot id: A0A6P7Y5A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

1415580:WNT2
gene id: 1415580:WNT2
uniprot id: A0A6P7ZBC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

1415580:NIT2
gene id: 1415580:NIT2
uniprot id: A0A6P7Y4C6
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1415580:PIGP
gene id: 1415580:PIGP
uniprot id: A0A6P7XYS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGP family.
messages: Membrane
messages: Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

1415580:ISL1
gene id: 1415580:ISL1
uniprot id: A0A6P7X3Y8
names: Subcellular Location Annotation
messages: Nucleus

1415580:DDX20
gene id: 1415580:DDX20
uniprot id: A0A6P7ZUX1
uniprot id: A0A6P7ZVN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family.
messages: Cytoplasm

1415580:PPP2R5C
gene id: 1415580:PPP2R5C
uniprot id: A0A6P7YW91
uniprot id: A0A6P7Z286
uniprot id: A0A6P7Z430
uniprot id: A0A6P7Z6P0
uniprot id: A0A6P7Z7M3
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

1415580:ATRX
gene id: 1415580:ATRX
uniprot id: A0A6P7YI65
uniprot id: A0A6P7YNC5
uniprot id: A0A6P7YNR6
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

1415580:LOC115469333
gene id: 1415580:LOC115469333
uniprot id: A0A6P7XXN5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115470904
gene id: 1415580:LOC115470904
uniprot id: A0A6P7YC29
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

1415580:DLC1
gene id: 1415580:DLC1
uniprot id: A0A6P7X1Q3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality.
messages: Interacts with EF1A1, facilitates EF1A1 distribution to the membrane periphery and ruffles upon growth factor stimulation and suppresses cell migration.
messages: Membrane
messages: focal adhesion

1415580:IMP4
gene id: 1415580:IMP4
uniprot id: A0A6P7X2P6
names: Subcellular Location Annotation
messages: nucleolus

1415580:DRAM1
gene id: 1415580:DRAM1
uniprot id: A0A6P7Z2F3
uniprot id: A0A6P7Z599
uniprot id: A0A6P7Z668
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115474593
gene id: 1415580:LOC115474593
uniprot id: A0A6P7YRV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC7 RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

1415580:LOC115475024
gene id: 1415580:LOC115475024
uniprot id: A0A6P7YNM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115476142
gene id: 1415580:LOC115476142
uniprot id: A0A6P7YXL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115476062
gene id: 1415580:LOC115476062
uniprot id: A0A6P7YTR4
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

1415580:ACADL
gene id: 1415580:ACADL
uniprot id: A0A6P7YTU8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Homotetramer.
messages: Mitochondrion matrix

1415580:SEC24D
gene id: 1415580:SEC24D
uniprot id: A0A6P7X2P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

1415580:LOC115464624
gene id: 1415580:LOC115464624
uniprot id: A0A6P7XEB7
names: Subcellular Location Annotation
messages: Nucleus

1415580:SUMF2
gene id: 1415580:SUMF2
uniprot id: A0A6P7ZNP1
uniprot id: A0A6P7ZXF5
uniprot id: A0A6P8A1E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase-modifying factor family.
messages: Endoplasmic reticulum lumen

1415580:UNCX
gene id: 1415580:UNCX
uniprot id: A0A6P7YYB9
names: Subcellular Location Annotation
messages: Nucleus

1415580:SLC35E1
gene id: 1415580:SLC35E1
uniprot id: A0A6P7ZBC5
names: Subcellular Location Annotation
messages: Membrane

1415580:ORAI1
gene id: 1415580:ORAI1
uniprot id: A0A6P7Z4C9
uniprot id: A0A6P7Z9D5
uniprot id: A0A6P7ZCA1
uniprot id: A0A6P7ZF00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

1415580:LOC115474849
gene id: 1415580:LOC115474849
uniprot id: A0A6P7X269
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115459869
gene id: 1415580:LOC115459869
uniprot id: A0A6P7WQQ3
uniprot id: A0A6P7WWL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

1415580:HMGB1
gene id: 1415580:HMGB1
uniprot id: A0A6P7Y086
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome
messages: Secreted

1415580:NEK8
gene id: 1415580:NEK8
uniprot id: A0A6P7WNF5
uniprot id: A0A6P7WVI9
names: Similarity
messages: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.

1415580:LOC115460501
gene id: 1415580:LOC115460501
uniprot id: A0A6P7X6B6
names: Similarity
messages: Belongs to the MS4A family.

1415580:PPP1R14C
gene id: 1415580:PPP1R14C
uniprot id: A0A6P7X718
uniprot id: A0A6P7XFY1
names: Similarity
messages: Belongs to the PP1 inhibitor family.

1415580:LOC115457591
gene id: 1415580:LOC115457591
uniprot id: A0A6P7WRC4
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

1415580:LOC115473127
gene id: 1415580:LOC115473127
uniprot id: A0A6P7YKP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1415580:CAMK2B
gene id: 1415580:CAMK2B
uniprot id: A0A6P7XQB7
uniprot id: A0A6P7XQC2
uniprot id: A0A6P7XQC8
uniprot id: A0A6P7XQD2
uniprot id: A0A6P7XX77
uniprot id: A0A6P7XX82
uniprot id: A0A6P7XX87
uniprot id: A0A6P7XX92
uniprot id: A0A6P7XYD0
uniprot id: A0A6P7XYE2
uniprot id: A0A6P7XYE8
uniprot id: A0A6P7Y3H1
uniprot id: A0A6P7Y3H5
uniprot id: A0A6P7Y3H9
uniprot id: A0A6P7Y3I3
uniprot id: A0A6P7Y3I7
uniprot id: A0A6P7Y481
uniprot id: A0A6P7Y486
uniprot id: A0A6P7Y492
uniprot id: A0A6P7Y497
uniprot id: A0A6P7Y4A2
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

1415580:LOC115456472
gene id: 1415580:LOC115456472
uniprot id: A0A6P7WMC0
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

1415580:ALG2
gene id: 1415580:ALG2
uniprot id: A0A6P7YD83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.
messages: Membrane

1415580:BCL2
gene id: 1415580:BCL2
uniprot id: A0A6P7YK76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: Nucleus membrane

1415580:MYO19
gene id: 1415580:MYO19
uniprot id: A0A6P7WUD0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

1415580:MLST8
gene id: 1415580:MLST8
uniprot id: A0A6P7YU17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LST8 family.
messages: Cytoplasm
messages: Part of TORC1 complex. Part of the TORC2 complex.
messages: Subunit of TORC1 and TORC2, which regulate cell growth and survival in response to nutrient and hormonal signals.

1415580:KCNG1
gene id: 1415580:KCNG1
uniprot id: A0A6P7YU47
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115457016
gene id: 1415580:LOC115457016
uniprot id: A0A6P7WMK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:ANXA8
gene id: 1415580:ANXA8
uniprot id: A0A6P7Y7B7
names: Similarity
messages: Belongs to the annexin family.

1415580:MFSD11
gene id: 1415580:MFSD11
uniprot id: A0A6P7YGH2
uniprot id: A0A6P7YLU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

1415580:LOC115469265
gene id: 1415580:LOC115469265
uniprot id: A0A6P7Y3J2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1415580:CLIC1
gene id: 1415580:CLIC1
uniprot id: A0A6P7XRK5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

1415580:LOC115481417
gene id: 1415580:LOC115481417
uniprot id: A0A6P7ZQA7
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

1415580:MYO18B
gene id: 1415580:MYO18B
uniprot id: A0A6P7Z3K3
uniprot id: A0A6P7ZE63
uniprot id: A0A6P7ZER0
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LCK
gene id: 1415580:LCK
uniprot id: A0A6P7ZCP8
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

1415580:PRKX
gene id: 1415580:PRKX
uniprot id: A0A6P7XRC3
uniprot id: A0A6P7XYC2
names: Similarity
messages: Belongs to the protein kinase superfamily.

1415580:AGPAT4
gene id: 1415580:AGPAT4
uniprot id: A0A6P7XEI4
uniprot id: A0A6P7XTE2
uniprot id: A0A6P7XU24
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

1415580:TMEM47
gene id: 1415580:TMEM47
uniprot id: A0A6P7Y076
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

1415580:EXO1
gene id: 1415580:EXO1
uniprot id: A0A6P7XCV7
uniprot id: A0A6P7XL62
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.
messages: Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Nucleus

1415580:RPS19
gene id: 1415580:RPS19
uniprot id: A0A6P7WMJ1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS19 family.

1415580:SF3A1
gene id: 1415580:SF3A1
uniprot id: A0A6P7Z553
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115457477
gene id: 1415580:LOC115457477
uniprot id: A0A6P7WWX7
names: Similarity
messages: Belongs to the FMR1 family.

1415580:OGN
gene id: 1415580:OGN
uniprot id: A0A6P7YD63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.
messages: Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.
messages: extracellular matrix

1415580:KATNA1
gene id: 1415580:KATNA1
uniprot id: A0A6P7XEE9
uniprot id: A0A6P7XL47
uniprot id: A0A6P7XTA6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
messages: Cytoplasm
messages: centrosome
messages: spindle
messages: spindle pole

1415580:CHEK1
gene id: 1415580:CHEK1
uniprot id: A0A6P7YSH6
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.

1415580:ST6GALNAC5
gene id: 1415580:ST6GALNAC5
uniprot id: A0A6P7YAZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

1415580:TP53I11
gene id: 1415580:TP53I11
uniprot id: A0A6P7XMT4
names: Subcellular Location Annotation
messages: Membrane

1415580:OPA3
gene id: 1415580:OPA3
uniprot id: A0A6P7ZDC7
names: Function
names: Similarity
messages: Belongs to the OPA3 family.
messages: May play some role in mitochondrial processes.

1415580:MAP2K1
gene id: 1415580:MAP2K1
uniprot id: A0A6P7X504
names: Similarity
messages: Belongs to the protein kinase superfamily.

1415580:KCNA4
gene id: 1415580:KCNA4
uniprot id: A0A6P7XQC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.4/KCNA4 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: axon

1415580:TRPC3
gene id: 1415580:TRPC3
uniprot id: A0A6P7X2M2
names: Subcellular Location Annotation
messages: Membrane

1415580:NKAIN1
gene id: 1415580:NKAIN1
uniprot id: A0A6P7ZGE7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Interacts with atp1b1 C-terminus.
messages: Membrane

1415580:DHTKD1
gene id: 1415580:DHTKD1
uniprot id: A0A6P7Z960
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

1415580:ATL3
gene id: 1415580:ATL3
uniprot id: A0A6P7Z8C0
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

1415580:QTRT1
gene id: 1415580:QTRT1
uniprot id: A0A6P7XR42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1' of the ribose to form the product.
messages: Cytoplasm
messages: Heterodimer of a catalytic subunit QTRT1 and an accessory subunit QTRT2.
messages: Mitochondrion outer membrane

1415580:LOC115457058
gene id: 1415580:LOC115457058
uniprot id: A0A6P7WGH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115469123
gene id: 1415580:LOC115469123
uniprot id: A0A6P7XWH3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Interacts with CHP1 and CHP2.
messages: Membrane

1415580:CD79B
gene id: 1415580:CD79B
uniprot id: A0A6P7ZGL2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:DMRT3
gene id: 1415580:DMRT3
uniprot id: A0A6P7X4J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

1415580:LOC115478931
gene id: 1415580:LOC115478931
uniprot id: A0A6P7Z4X3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:WDFY1
gene id: 1415580:WDFY1
uniprot id: A0A6P7Z719
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

1415580:LOC115482548
gene id: 1415580:LOC115482548
uniprot id: A0A6P7ZMU7
names: Similarity
messages: Belongs to the peptidase C1 family.

1415580:SMIM24
gene id: 1415580:SMIM24
uniprot id: A0A6P7ZBV6
uniprot id: A0A6P7ZKR9
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115457320
gene id: 1415580:LOC115457320
uniprot id: A0A6P7WWH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:PDE10A
gene id: 1415580:PDE10A
uniprot id: A0A6P7XL74
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

1415580:LOC115479472
gene id: 1415580:LOC115479472
uniprot id: A0A6P7WV85
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1415580:HEXB
gene id: 1415580:HEXB
uniprot id: A0A6P7XER4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 20 family.
messages: Lysosome

1415580:VMA21
gene id: 1415580:VMA21
uniprot id: A0A6P7YPP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VMA21 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.

1415580:RAG2
gene id: 1415580:RAG2
uniprot id: A0A6P7XS54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAG2 family.
messages: Nucleus

1415580:GLI1
gene id: 1415580:GLI1
uniprot id: A0A6P7XQ34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

1415580:CEP44
gene id: 1415580:CEP44
uniprot id: A0A6P7WW25
uniprot id: A0A6P7X215
uniprot id: A0A6P7XA03
uniprot id: A0A6P7XB83
names: Subcellular Location Annotation
messages: Midbody
messages: centriole
messages: spindle pole

1415580:CNP
gene id: 1415580:CNP
uniprot id: A0A6P7ZH47
uniprot id: A0A6P7ZVG6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 2H phosphoesterase superfamily. CNPase family.
messages: Exists as monomers and homodimers.
messages: Melanosome
messages: Membrane

1415580:PAMR1
gene id: 1415580:PAMR1
uniprot id: A0A6P7XUJ2
uniprot id: A0A6P7Y1E7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115468423
gene id: 1415580:LOC115468423
uniprot id: A0A6P7XKJ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS21 family.
messages: Component of the 40S small ribosomal subunit.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum
messages: cytosol

1415580:CD28
gene id: 1415580:CD28
uniprot id: A0A6P7YKL7
names: Subcellular Location Annotation
messages: Membrane

1415580:ACVR1B
gene id: 1415580:ACVR1B
uniprot id: A0A6P7XJP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

1415580:ITPK1
gene id: 1415580:ITPK1
uniprot id: A0A6P7Z086
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ITPK1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3.
messages: Monomer.

1415580:LOC115468789
gene id: 1415580:LOC115468789
uniprot id: A0A6P7XUI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
messages: Peroxisome

1415580:STAMBP
gene id: 1415580:STAMBP
uniprot id: A0A6P7XXG8
uniprot id: A0A6P7XXH3
names: Similarity
messages: Belongs to the peptidase M67C family.

1415580:CLUH
gene id: 1415580:CLUH
uniprot id: A0A6P7WLZ3
uniprot id: A0A6P7WNZ0
uniprot id: A0A6P7WUZ3
uniprot id: A0A6P7WW03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLU family.
messages: Cytoplasm
messages: Cytoplasmic granule
messages: mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear-encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis.

1415580:PTGIS
gene id: 1415580:PTGIS
uniprot id: A0A6P7YQT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

1415580:GLOD4
gene id: 1415580:GLOD4
uniprot id: A0A6P7ZVN2
uniprot id: A0A6P7ZYR7
names: Similarity
messages: Belongs to the glyoxalase I family.

1415580:LGR4
gene id: 1415580:LGR4
uniprot id: A0A6P7XMG8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:TUBGCP3
gene id: 1415580:TUBGCP3
uniprot id: A0A6P7Y3H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

1415580:PLD1
gene id: 1415580:PLD1
uniprot id: A0A6P7Z9L0
names: Similarity
messages: Belongs to the phospholipase D family.

1415580:KCNH8
gene id: 1415580:KCNH8
uniprot id: A0A6P7Y753
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

1415580:ATAD2B
gene id: 1415580:ATAD2B
uniprot id: A0A6P7XQ52
names: Similarity
messages: Belongs to the AAA ATPase family.

1415580:SLC34A1
gene id: 1415580:SLC34A1
uniprot id: A0A6P7YQF7
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Membrane

1415580:LOC115469944
gene id: 1415580:LOC115469944
uniprot id: A0A6P7Y192
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

1415580:ASTE1
gene id: 1415580:ASTE1
uniprot id: A0A6P7Y460
names: Similarity
messages: Belongs to the asteroid family.

1415580:LOC115457964
gene id: 1415580:LOC115457964
uniprot id: A0A6P7WT20
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115473714
gene id: 1415580:LOC115473714
uniprot id: A0A6P7YN52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cell membrane

1415580:LOC115472909
gene id: 1415580:LOC115472909
uniprot id: A0A6P7WTK9
names: Similarity
messages: Belongs to the serpin family.

1415580:TFEB
gene id: 1415580:TFEB
uniprot id: A0A6P7ZNK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

1415580:LOC115467294
gene id: 1415580:LOC115467294
uniprot id: A0A6P7XHN8
uniprot id: A0A6P7XPD5
uniprot id: A0A6P7XPE1
uniprot id: A0A6P7XR65
uniprot id: A0A6P7XWB9
uniprot id: A0A6P7XWC3
uniprot id: A0A6P7XX11
uniprot id: A0A6P7XX14
names: Similarity
messages: Belongs to the PICALM/SNAP91 family.

1415580:SLC25A37
gene id: 1415580:SLC25A37
uniprot id: A0A6P7Y4J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1415580:LOC115479300
gene id: 1415580:LOC115479300
uniprot id: A0A6P7ZBH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistin/FIZZ family.
messages: Secreted

1415580:VPS72
gene id: 1415580:VPS72
uniprot id: A0A6P7WIB7
uniprot id: A0A6P7WRN2
names: Function
names: Similarity
messages: Belongs to the VPS72/YL1 family.
messages: Deposition-and-exchange histone chaperone specific for H2AZ1, specifically chaperones H2AZ1 and deposits it into nucleosomes. As component of the SRCAP complex, mediates the ATP-dependent exchange of histone H2AZ1/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling.

1415580:BPI
gene id: 1415580:BPI
uniprot id: A0A6P7YHY8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Cytoplasmic granule membrane
messages: Membrane
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

1415580:SIDT1
gene id: 1415580:SIDT1
uniprot id: A0A6P7Y9K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SID1 family.
messages: Membrane

1415580:LOC115466749
gene id: 1415580:LOC115466749
uniprot id: A0A6P7XNE2
names: Similarity
messages: Belongs to the intermediate filament family.

1415580:SEPTIN11
gene id: 1415580:SEPTIN11
uniprot id: A0A6P7WZ71
uniprot id: A0A6P7X1S5
uniprot id: A0A6P7X763
uniprot id: A0A6P7X773
uniprot id: A0A6P7X8D7
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

1415580:LOC115468303
gene id: 1415580:LOC115468303
uniprot id: A0A6P7XK12
uniprot id: A0A6P7XTG8
uniprot id: A0A6P7XYK8
uniprot id: A0A6P7XZ82
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115457583
gene id: 1415580:LOC115457583
uniprot id: A0A6P7WHZ7
uniprot id: A0A6P7WPA5
uniprot id: A0A6P7WRA1
uniprot id: A0A6P7WXA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Cytoplasm
messages: Nucleus

1415580:LOC115467099
gene id: 1415580:LOC115467099
uniprot id: A0A6P7XGL1
names: Similarity
messages: Belongs to the EVA1 family.

1415580:SLC16A6
gene id: 1415580:SLC16A6
uniprot id: A0A6P7YH34
names: Subcellular Location Annotation
messages: Membrane

1415580:KCNK6
gene id: 1415580:KCNK6
uniprot id: A0A6P7ZEX8
uniprot id: A0A6P7ZJL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: Recycling endosome
messages: Synaptic cell membrane
messages: Vesicle
messages: dendrite

1415580:BCL2L14
gene id: 1415580:BCL2L14
uniprot id: A0A6P7YV70
uniprot id: A0A6P7Z2Y2
names: Similarity
messages: Belongs to the Bcl-2 family.

1415580:ACVR2A
gene id: 1415580:ACVR2A
uniprot id: A0A6P7YIJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

1415580:LOC115463334
gene id: 1415580:LOC115463334
uniprot id: A0A6P7X8F2
names: Similarity
messages: Belongs to the thioredoxin family.

1415580:CDK8
gene id: 1415580:CDK8
uniprot id: A0A6P7XLA2
uniprot id: A0A6P7XUJ3
names: Similarity
messages: Belongs to the protein kinase superfamily.

1415580:LOC115462424
gene id: 1415580:LOC115462424
uniprot id: A0A6P7XCH2
names: Similarity
messages: Belongs to the perilipin family.

1415580:GLT8D1
gene id: 1415580:GLT8D1
uniprot id: A0A6P7YKK9
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115466835
gene id: 1415580:LOC115466835
uniprot id: A0A6P7XM33
names: Similarity
messages: Belongs to the TCAF family.

1415580:SATB2
gene id: 1415580:SATB2
uniprot id: A0A6P7YMV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

1415580:MSH5
gene id: 1415580:MSH5
uniprot id: A0A6P7XBB0
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.

1415580:LOC115457061
gene id: 1415580:LOC115457061
uniprot id: A0A6P7WVS3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LOC115478342
gene id: 1415580:LOC115478342
uniprot id: A0A6P7Z4D0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: dendrite

1415580:B4GALNT2
gene id: 1415580:B4GALNT2
uniprot id: A0A6P7ZCN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Membrane

1415580:DDI2
gene id: 1415580:DDI2
uniprot id: A0A6P7WU05
uniprot id: A0A6P7WV13
names: Similarity
messages: Belongs to the DDI1 family.

1415580:HMGB2
gene id: 1415580:HMGB2
uniprot id: A0A6P7X4M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

1415580:LOC115464337
gene id: 1415580:LOC115464337
uniprot id: A0A6P7XB98
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

1415580:STARD3NL
gene id: 1415580:STARD3NL
uniprot id: A0A6P7XWQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STARD3 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

1415580:LOC115479552
gene id: 1415580:LOC115479552
uniprot id: A0A6P7Z9Y0
uniprot id: A0A6P7ZDB3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1415580:LOC115477537
gene id: 1415580:LOC115477537
uniprot id: A0A6P7YZG1
uniprot id: A0A6P7Z3M2
names: Subcellular Location Annotation
messages: Membrane

1415580:DIS3
gene id: 1415580:DIS3
uniprot id: A0A6P7Y0D2
names: Similarity
messages: Belongs to the RNR ribonuclease family.

1415580:TAF5L
gene id: 1415580:TAF5L
uniprot id: A0A6P7XIS0
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

1415580:ABCC3
gene id: 1415580:ABCC3
uniprot id: A0A6P7Y8M2
uniprot id: A0A6P7YFM8
uniprot id: A0A6P7YL56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

1415580:LOC115460511
gene id: 1415580:LOC115460511
uniprot id: A0A6P7X0Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:CDC42EP4
gene id: 1415580:CDC42EP4
uniprot id: A0A6P7YAA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

1415580:THG1L
gene id: 1415580:THG1L
uniprot id: A0A6P7YYI4
names: Cofactor
names: Function
names: Similarity
messages: Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
messages: Belongs to the tRNA(His) guanylyltransferase family.
messages: Binds 2 magnesium ions per subunit.

1415580:EED
gene id: 1415580:EED
uniprot id: A0A6P7XZ21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ESC family.
messages: Nucleus

1415580:KIF13B
gene id: 1415580:KIF13B
uniprot id: A0A6P7XV73
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

1415580:LOC115460185
gene id: 1415580:LOC115460185
uniprot id: A0A6P7X057
names: Similarity
messages: Belongs to the MSANTD3 family.

1415580:RFX1
gene id: 1415580:RFX1
uniprot id: A0A6P7XQ01
uniprot id: A0A6P7XQ05
uniprot id: A0A6P7XQS2
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115475015
gene id: 1415580:LOC115475015
uniprot id: A0A6P7YTM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115476822
gene id: 1415580:LOC115476822
uniprot id: A0A6P7YWB2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1415580:ZFP36L2
gene id: 1415580:ZFP36L2
uniprot id: A0A6P7X4C7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

1415580:BMP10
gene id: 1415580:BMP10
uniprot id: A0A6P7XSI9
names: Similarity
messages: Belongs to the TGF-beta family.

1415580:NOP53
gene id: 1415580:NOP53
uniprot id: A0A6P7ZEQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP53 family.
messages: May play a role in ribosome biogenesis.
messages: nucleolus
messages: nucleoplasm

1415580:CFAP97
gene id: 1415580:CFAP97
uniprot id: A0A6P7WVZ1
names: Similarity
messages: Belongs to the CFAP97 family.

1415580:ATP23
gene id: 1415580:ATP23
uniprot id: A0A6P7Z767
uniprot id: A0A6P7ZAN3
names: Similarity
messages: Belongs to the peptidase M76 family.

1415580:MYOG
gene id: 1415580:MYOG
uniprot id: A0A6P7ZUE4
names: Subcellular Location Annotation
messages: Nucleus

1415580:TMEM121B
gene id: 1415580:TMEM121B
uniprot id: A0A6P7YYK4
names: Similarity
messages: Belongs to the TMEM121 family.

1415580:LOC115479469
gene id: 1415580:LOC115479469
uniprot id: A0A6P7Z9J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

1415580:MTG1
gene id: 1415580:MTG1
uniprot id: A0A6P7Y2I0
uniprot id: A0A6P7Y7F1
uniprot id: A0A6P7Y8C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Mitochondrion inner membrane
messages: Plays a role in the regulation of the mitochondrial ribosome assembly and of translational activity. Displays mitochondrial GTPase activity.

1415580:PPIP5K1
gene id: 1415580:PPIP5K1
uniprot id: A0A6P7WZ38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytosol

1415580:RBL1
gene id: 1415580:RBL1
uniprot id: A0A6P7YJ30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

1415580:FAM168A
gene id: 1415580:FAM168A
uniprot id: A0A6P7XTP9
names: Similarity
messages: Belongs to the FAM168 family.

1415580:LOC115478488
gene id: 1415580:LOC115478488
uniprot id: A0A6P7Z7L6
uniprot id: A0A6P7Z8G7
names: Similarity
messages: Belongs to the p23/wos2 family.

1415580:FOXI2
gene id: 1415580:FOXI2
uniprot id: A0A6P7Y6Q0
names: Subcellular Location Annotation
messages: Nucleus

1415580:INSRR
gene id: 1415580:INSRR
uniprot id: A0A6P7WZZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

1415580:FAM221A
gene id: 1415580:FAM221A
uniprot id: A0A6P7XQR2
uniprot id: A0A6P7XXP8
names: Similarity
messages: Belongs to the FAM221 family.

1415580:MFSD10
gene id: 1415580:MFSD10
uniprot id: A0A6P7WV02
uniprot id: A0A6P7X3F7
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115464461
gene id: 1415580:LOC115464461
uniprot id: A0A6P7XJ73
names: Similarity
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.

1415580:PLD2
gene id: 1415580:PLD2
uniprot id: A0A6P7WQQ6
uniprot id: A0A6P7WYU5
names: Similarity
messages: Belongs to the phospholipase D family.

1415580:PTP4A2
gene id: 1415580:PTP4A2
uniprot id: A0A6P7ZL49
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

1415580:MACF1
gene id: 1415580:MACF1
uniprot id: A0A6P7ZPT3
names: Subcellular Location Annotation
messages: cytoskeleton

1415580:SLC35B3
gene id: 1415580:SLC35B3
uniprot id: A0A6P7YP64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

1415580:SH3GL2
gene id: 1415580:SH3GL2
uniprot id: A0A6P7XIH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Membrane

1415580:ANKRD34B
gene id: 1415580:ANKRD34B
uniprot id: A0A6P7WY40
uniprot id: A0A6P7X6U0
names: Similarity
messages: Belongs to the ANKRD34 family.

1415580:LOC115457726
gene id: 1415580:LOC115457726
uniprot id: A0A6P7WYZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:GUK1
gene id: 1415580:GUK1
uniprot id: A0A6P7XRG3
uniprot id: A0A6P7XS57
names: Similarity
messages: Belongs to the guanylate kinase family.

1415580:LOC115457122
gene id: 1415580:LOC115457122
uniprot id: A0A6P7WGN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

1415580:LOC115475638
gene id: 1415580:LOC115475638
uniprot id: A0A6P7YIU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

1415580:WASF1
gene id: 1415580:WASF1
uniprot id: A0A6P7XX67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

1415580:PSMC4
gene id: 1415580:PSMC4
uniprot id: A0A6P7YTB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC4 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
messages: Cytoplasm

1415580:LOC115478322
gene id: 1415580:LOC115478322
uniprot id: A0A6P7Z7V4
names: Similarity
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.

1415580:LOC115458438
gene id: 1415580:LOC115458438
uniprot id: A0A6P7X138
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115464419
gene id: 1415580:LOC115464419
uniprot id: A0A6P7XBI3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LOC115458200
gene id: 1415580:LOC115458200
uniprot id: A0A6P7X060
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115471793
gene id: 1415580:LOC115471793
uniprot id: A0A6P7Y1S7
names: Similarity
messages: Belongs to the cytochrome P450 family.

1415580:TAFA3
gene id: 1415580:TAFA3
uniprot id: A0A6P7ZJT2
names: Similarity
messages: Belongs to the TAFA family.

1415580:LOC115475844
gene id: 1415580:LOC115475844
uniprot id: A0A6P7YJT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

1415580:TICAM1
gene id: 1415580:TICAM1
uniprot id: A0A6P7ZDW7
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer. Found in a multi-helicase-TICAM1 complex at least composed of DHX36, DDX1, DDX21 and TICAM1.
messages: Involved in innate immunity against invading pathogens. Adapter used by TLR3, TLR4 (through TICAM2) and TLR5 to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively. Phosphorylation by TBK1 on the pLxIS motif leads to recruitment and subsequent activation of the transcription factor IRF3 to induce expression of type I interferon and exert a potent immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of pro-inflammatory cytokines.
messages: Mitochondrion
messages: The N-terminal region is essential for activation of the IFNB promoter activity.
messages: autophagosome
messages: cytosol

1415580:C6H1orf52
gene id: 1415580:C6H1orf52
uniprot id: A0A6P7YID2
names: Similarity
messages: Belongs to the UPF0690 family.

1415580:LOC115464723
gene id: 1415580:LOC115464723
uniprot id: A0A6P7XCI0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:PROX2
gene id: 1415580:PROX2
uniprot id: A0A6P7YYI1
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115457067
gene id: 1415580:LOC115457067
uniprot id: A0A6P7WGI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:GNA13
gene id: 1415580:GNA13
uniprot id: A0A6P7YMT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

1415580:COPS7B
gene id: 1415580:COPS7B
uniprot id: A0A6P7Z057
uniprot id: A0A6P7Z7Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
messages: Cytoplasm
messages: Nucleus

1415580:LOC115457209
gene id: 1415580:LOC115457209
uniprot id: A0A6P7WW61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:ZNF280D
gene id: 1415580:ZNF280D
uniprot id: A0A6P7X446
names: Function
names: Subcellular Location Annotation
messages: May function as a transcription factor.
messages: Nucleus

1415580:LOC115462494
gene id: 1415580:LOC115462494
uniprot id: A0A6P7WYN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAIF1 family.
messages: Induces apoptosis.
messages: Nucleus

1415580:LOC115457317
gene id: 1415580:LOC115457317
uniprot id: A0A6P7WNF3
names: Similarity
messages: Belongs to the actin family.

1415580:TPH1
gene id: 1415580:TPH1
uniprot id: A0A6P7X5H6
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

1415580:LOC115482230
gene id: 1415580:LOC115482230
uniprot id: A0A6P7ZUT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

1415580:TTLL9
gene id: 1415580:TTLL9
uniprot id: A0A6P7YQQ6
uniprot id: A0A6P7YUV6
uniprot id: A0A6P7YUW9
names: Similarity
messages: Belongs to the tubulin--tyrosine ligase family.

1415580:SNRPE
gene id: 1415580:SNRPE
uniprot id: A0A6P7ZV08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.

1415580:SNRNP27
gene id: 1415580:SNRNP27
uniprot id: A0A6P7XZP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNUT3 family.
messages: May play a role in mRNA splicing.
messages: Nucleus
messages: Part of a tri-snRNP complex.

1415580:SET
gene id: 1415580:SET
uniprot id: A0A6P7Y8F8
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

1415580:TOMM5
gene id: 1415580:TOMM5
uniprot id: A0A6P7X7B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom5 family.
messages: Membrane
messages: Mitochondrion outer membrane

1415580:ARL6IP5
gene id: 1415580:ARL6IP5
uniprot id: A0A6P7YBZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

1415580:LCA5L
gene id: 1415580:LCA5L
uniprot id: A0A6P7Y3K4
names: Similarity
messages: Belongs to the LCA5 family.

1415580:LPAR2
gene id: 1415580:LPAR2
uniprot id: A0A6P7XRX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cell surface
messages: Endosome
messages: Membrane

1415580:LOC115473532
gene id: 1415580:LOC115473532
uniprot id: A0A6P7YMN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

1415580:MDFI
gene id: 1415580:MDFI
uniprot id: A0A6P7ZS02
uniprot id: A0A6P7ZUC4
names: Similarity
messages: Belongs to the MDFI family.

1415580:AP2M1
gene id: 1415580:AP2M1
uniprot id: A0A6P7ZBB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Cell membrane
messages: coated pit

1415580:ABL1
gene id: 1415580:ABL1
uniprot id: A0A6P7Y837
uniprot id: A0A6P7YF57
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

1415580:WAPL
gene id: 1415580:WAPL
uniprot id: A0A6P7YDF8
names: Similarity
messages: Belongs to the WAPL family.

1415580:SLC4A4
gene id: 1415580:SLC4A4
uniprot id: A0A6P7WTJ7
uniprot id: A0A6P7WZD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

1415580:LOC115475394
gene id: 1415580:LOC115475394
uniprot id: A0A6P7YPI9
uniprot id: A0A6P7YQC9
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.

1415580:LOC115466520
gene id: 1415580:LOC115466520
uniprot id: A0A6P7XMA5
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

1415580:GPT2
gene id: 1415580:GPT2
uniprot id: A0A6P7Y5G3
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

1415580:NTSR2
gene id: 1415580:NTSR2
uniprot id: A0A6P7XCQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:SF3A2
gene id: 1415580:SF3A2
uniprot id: A0A6P7ZAQ5
names: Similarity
messages: Belongs to the SF3A2 family.

1415580:TRHDE
gene id: 1415580:TRHDE
uniprot id: A0A6P7Z1U4
names: Similarity
messages: Belongs to the peptidase M1 family.

1415580:EZH1
gene id: 1415580:EZH1
uniprot id: A0A6P7ZVA0
names: Subcellular Location Annotation
messages: Nucleus

1415580:TIMP4
gene id: 1415580:TIMP4
uniprot id: A0A6P7Y1M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I35 (TIMP) family.
messages: Secreted

1415580:RPS20
gene id: 1415580:RPS20
uniprot id: A0A6P7Z4M8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Component of the 40S small ribosomal subunit.

1415580:LOC115469404
gene id: 1415580:LOC115469404
uniprot id: A0A6P7XR64
names: Similarity
messages: Belongs to the PHYHIP family.

1415580:ST8SIA4
gene id: 1415580:ST8SIA4
uniprot id: A0A6P7X9W2
uniprot id: A0A6P7XGA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

1415580:LOC115465316
gene id: 1415580:LOC115465316
uniprot id: A0A6P7WNI3
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1415580:LOC115480026
gene id: 1415580:LOC115480026
uniprot id: A0A6P7X5J9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1415580:ATP10A
gene id: 1415580:ATP10A
uniprot id: A0A6P7XWA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

1415580:TGFB2
gene id: 1415580:TGFB2
uniprot id: A0A6P7X8G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.
messages: extracellular matrix

1415580:LOC115460521
gene id: 1415580:LOC115460521
uniprot id: A0A6P7X7G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:TULP1
gene id: 1415580:TULP1
uniprot id: A0A6P7ZTV9
names: Similarity
messages: Belongs to the TUB family.

1415580:TMEM186
gene id: 1415580:TMEM186
uniprot id: A0A6P7YX39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM186 family.
messages: Membrane

1415580:EXOC5
gene id: 1415580:EXOC5
uniprot id: A0A6P7YUY9
uniprot id: A0A6P7Z181
names: Function
names: Similarity
messages: Belongs to the SEC10 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

1415580:RTCB
gene id: 1415580:RTCB
uniprot id: A0A6P7Z6I6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Catalytic component of the tRNA-splicing ligase complex.
messages: Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
messages: Cytoplasm
messages: Ligation probably proceeds through 3 nucleotidyl transfer steps, with 2',3'-cyclic phosphate termini being hydrolyzed to 3'-P termini in a step that precedes 3'-P activation with GMP. In the first nucleotidyl transfer step, RTCB reacts with GTP to form a covalent RTCB-histidine-GMP intermediate with release of PPi; in the second step, the GMP moiety is transferred to the RNA 3'-P; in the third step, the 5'-OH from the opposite RNA strand attacks the activated 3'-P to form a 3',5'-phosphodiester bond and release GMP.

1415580:TXLNG
gene id: 1415580:TXLNG
uniprot id: A0A6P7XJ82
names: Similarity
messages: Belongs to the taxilin family.

1415580:LAMB2
gene id: 1415580:LAMB2
uniprot id: A0A6P7Y2W1
uniprot id: A0A6P7Y9Y5
uniprot id: A0A6P7YA90
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

1415580:LOC115464415
gene id: 1415580:LOC115464415
uniprot id: A0A6P7X4X2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:MB
gene id: 1415580:MB
uniprot id: A0A6P7YCT3
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

1415580:LOC115466013
gene id: 1415580:LOC115466013
uniprot id: A0A6P7XB63
uniprot id: A0A6P7XHZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

1415580:LOC115457968
gene id: 1415580:LOC115457968
uniprot id: A0A6P7WT25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115457348
gene id: 1415580:LOC115457348
uniprot id: A0A6P7WWJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:ING3
gene id: 1415580:ING3
uniprot id: A0A6P7YYV2
uniprot id: A0A6P7Z4K8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

1415580:NADK2
gene id: 1415580:NADK2
uniprot id: A0A6P7X044
uniprot id: A0A6P7X6I1
uniprot id: A0A6P7XE50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAD kinase family.
messages: Homodimer.
messages: Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor.
messages: Mitochondrion

1415580:ATRN
gene id: 1415580:ATRN
uniprot id: A0A6P7X8I0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:TSEN2
gene id: 1415580:TSEN2
uniprot id: A0A6P7ZVW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.
messages: Nucleus

1415580:CHMP1B
gene id: 1415580:CHMP1B
uniprot id: A0A6P7YQ40
uniprot id: A0A6P7YQG9
names: Similarity
messages: Belongs to the SNF7 family.

1415580:BZW2
gene id: 1415580:BZW2
uniprot id: A0A6P7WRK8
names: Similarity
messages: Belongs to the BZW family.

1415580:LOC115466932
gene id: 1415580:LOC115466932
uniprot id: A0A6P7XPC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

1415580:NOC2L
gene id: 1415580:NOC2L
uniprot id: A0A6P7ZV62
uniprot id: A0A6P7ZX68
names: Similarity
messages: Belongs to the NOC2 family.

1415580:LOC115462173
gene id: 1415580:LOC115462173
uniprot id: A0A6P7WXT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Cytoplasm
messages: Nucleus
messages: Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.

1415580:SARM1
gene id: 1415580:SARM1
uniprot id: A0A6P7WTK4
names: Similarity
messages: Belongs to the SARM1 family.

1415580:LOC115460531
gene id: 1415580:LOC115460531
uniprot id: A0A6P7X100
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:WDR35
gene id: 1415580:WDR35
uniprot id: A0A6P7XVJ1
names: Subcellular Location Annotation
messages: centrosome
messages: cilium basal body

1415580:MAU2
gene id: 1415580:MAU2
uniprot id: A0A6P7ZGY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC4/mau-2 family.
messages: nucleoplasm

1415580:CLN8
gene id: 1415580:CLN8
uniprot id: A0A6P7X7C0
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115464289
gene id: 1415580:LOC115464289
uniprot id: A0A6P7X4J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAIF1 family.
messages: Induces apoptosis.
messages: Nucleus

1415580:PSMA1
gene id: 1415580:PSMA1
uniprot id: A0A6P7XVA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

1415580:LOC115466193
gene id: 1415580:LOC115466193
uniprot id: A0A6P7XKW9
names: Similarity
messages: Belongs to the cytochrome P450 family.

1415580:DYSF
gene id: 1415580:DYSF
uniprot id: A0A6P7WUK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferlin family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

1415580:MMP28
gene id: 1415580:MMP28
uniprot id: A0A6P7WLK2
names: Similarity
messages: Belongs to the peptidase M10A family.

1415580:TMEM132E
gene id: 1415580:TMEM132E
uniprot id: A0A6P7WEZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

1415580:CHST2
gene id: 1415580:CHST2
uniprot id: A0A6P7Z9V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

1415580:RPL17
gene id: 1415580:RPL17
uniprot id: A0A6P7WZT5
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

1415580:LOC115475059
gene id: 1415580:LOC115475059
uniprot id: A0A6P7YGU2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

1415580:LOC115475451
gene id: 1415580:LOC115475451
uniprot id: A0A6P7YQN8
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

1415580:DNTT
gene id: 1415580:DNTT
uniprot id: A0A6P7Y6R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Nucleus
messages: Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator.

1415580:LOC115457254
gene id: 1415580:LOC115457254
uniprot id: A0A6P7WN94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:CD44
gene id: 1415580:CD44
uniprot id: A0A6P7XSA0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: microvillus

1415580:LOC115466451
gene id: 1415580:LOC115466451
uniprot id: A0A6P7XDA8
uniprot id: A0A6P7XSX3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:XRCC4
gene id: 1415580:XRCC4
uniprot id: A0A6P7X0Y7
uniprot id: A0A6P7X7D5
uniprot id: A0A6P7X9M8
uniprot id: A0A6P7XEY1
uniprot id: A0A6P7XG35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XRCC4-XLF family. XRCC4 subfamily.
messages: Nucleus

1415580:KLC1
gene id: 1415580:KLC1
uniprot id: A0A6P7YWC0
uniprot id: A0A6P7Z2A4
uniprot id: A0A6P7Z454
uniprot id: A0A6P7Z6R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

1415580:RAPGEF2
gene id: 1415580:RAPGEF2
uniprot id: A0A6P7WW76
uniprot id: A0A6P7WW81
uniprot id: A0A6P7X273
uniprot id: A0A6P7XA55
uniprot id: A0A6P7XBD7
uniprot id: A0A6P7XBE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAPGEF2 family.
messages: Cell junction
messages: Endosome
messages: Late endosome
messages: perinuclear region

1415580:LOC115480157
gene id: 1415580:LOC115480157
uniprot id: A0A6P7Z8J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

1415580:LOC115458216
gene id: 1415580:LOC115458216
uniprot id: A0A6P7WRX7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:ARHGEF18
gene id: 1415580:ARHGEF18
uniprot id: A0A6P7Z7T9
names: Subcellular Location Annotation
messages: Cytoplasm

1415580:PRKCH
gene id: 1415580:PRKCH
uniprot id: A0A6P7YZD5
uniprot id: A0A6P7Z3J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

1415580:SUPT5H
gene id: 1415580:SUPT5H
uniprot id: A0A6P7Z9P5
uniprot id: A0A6P7ZD32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT5 family.
messages: Nucleus

1415580:TLX1
gene id: 1415580:TLX1
uniprot id: A0A6P7XZD9
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115474560
gene id: 1415580:LOC115474560
uniprot id: A0A6P7YMD6
uniprot id: A0A6P7YRR3
uniprot id: A0A6P7YRX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

1415580:CNIH3
gene id: 1415580:CNIH3
uniprot id: A0A6P7XJM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

1415580:ST3GAL2
gene id: 1415580:ST3GAL2
uniprot id: A0A6P7Y3P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

1415580:SYNGR3
gene id: 1415580:SYNGR3
uniprot id: A0A6P7YU94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

1415580:MID1IP1
gene id: 1415580:MID1IP1
uniprot id: A0A6P7Y054
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

1415580:PACS2
gene id: 1415580:PACS2
uniprot id: A0A6P7Z329
names: Similarity
messages: Belongs to the PACS family.

1415580:AURKB
gene id: 1415580:AURKB
uniprot id: A0A6P7WUE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
messages: Chromosome

1415580:MTF2
gene id: 1415580:MTF2
uniprot id: A0A6P7Y8V2
uniprot id: A0A6P7YE72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

1415580:CD81
gene id: 1415580:CD81
uniprot id: A0A6P7XX15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

1415580:SLC18A2
gene id: 1415580:SLC18A2
uniprot id: A0A6P7XZ07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Vesicular transporter family.
messages: Membrane

1415580:ATP8B3
gene id: 1415580:ATP8B3
uniprot id: A0A6P7Z546
uniprot id: A0A6P7ZD81
uniprot id: A0A6P7ZGB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

1415580:FOXL2
gene id: 1415580:FOXL2
uniprot id: A0A6P7Z4U7
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115473702
gene id: 1415580:LOC115473702
uniprot id: A0A6P7YI73
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:SLC5A2
gene id: 1415580:SLC5A2
uniprot id: A0A6P7YDJ3
uniprot id: A0A6P7YKN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1415580:PI4K2A
gene id: 1415580:PI4K2A
uniprot id: A0A6P7YC26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane

1415580:LOC115457282
gene id: 1415580:LOC115457282
uniprot id: A0A6P7WWD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:SLC12A5
gene id: 1415580:SLC12A5
uniprot id: A0A6P7Z0P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

1415580:TRUB2
gene id: 1415580:TRUB2
uniprot id: A0A6P7Y5M2
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

1415580:SETD2
gene id: 1415580:SETD2
uniprot id: A0A6P7XHV1
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115460005
gene id: 1415580:LOC115460005
uniprot id: A0A6P7WRB8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1415580:LOC115457974
gene id: 1415580:LOC115457974
uniprot id: A0A6P7X090
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115457326
gene id: 1415580:LOC115457326
uniprot id: A0A6P7WWI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115479356
gene id: 1415580:LOC115479356
uniprot id: A0A6P7Z6L3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 6c family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

1415580:LOC115457728
gene id: 1415580:LOC115457728
uniprot id: A0A6P7WRZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115469281
gene id: 1415580:LOC115469281
uniprot id: A0A6P7XXG4
names: Similarity
messages: Belongs to the peptidase C14A family.

1415580:A4GALT
gene id: 1415580:A4GALT
uniprot id: A0A6P7Z1P2
uniprot id: A0A6P7Z620
uniprot id: A0A6P7Z6Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 32 family.
messages: Golgi apparatus membrane

1415580:NR1I2
gene id: 1415580:NR1I2
uniprot id: A0A6P7Y437
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

1415580:DMGDH
gene id: 1415580:DMGDH
uniprot id: A0A6P7XEM3
names: Similarity
messages: Belongs to the GcvT family.

1415580:LOC115458433
gene id: 1415580:LOC115458433
uniprot id: A0A6P7X132
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:CAPN8
gene id: 1415580:CAPN8
uniprot id: A0A6P7XHA9
names: Similarity
messages: Belongs to the peptidase C2 family.

1415580:SNW1
gene id: 1415580:SNW1
uniprot id: A0A6P7X279
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNW family.
messages: Identified in the spliceosome C complex.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

1415580:LOC115456848
gene id: 1415580:LOC115456848
uniprot id: A0A6P7WLV3
uniprot id: A0A6P7WUU6
uniprot id: A0A6P7WVV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Belongs to the mis12 family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Membrane
messages: kinetochore

1415580:PIP4P1
gene id: 1415580:PIP4P1
uniprot id: A0A6P7WY43
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

1415580:L3HYPDH
gene id: 1415580:L3HYPDH
uniprot id: A0A6P7YZ55
names: Similarity
messages: Belongs to the proline racemase family.

1415580:GCAT
gene id: 1415580:GCAT
uniprot id: A0A6P7YLJ0
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1415580:SLC25A1
gene id: 1415580:SLC25A1
uniprot id: A0A6P7ZB71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1415580:FUT10
gene id: 1415580:FUT10
uniprot id: A0A6P7X687
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane
messages: Probable fucosyltransferase.

1415580:GALNT3
gene id: 1415580:GALNT3
uniprot id: A0A6P7YLR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

1415580:PTPN21
gene id: 1415580:PTPN21
uniprot id: A0A6P7YQR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

1415580:B3GAT1
gene id: 1415580:B3GAT1
uniprot id: A0A6P7ZEI7
uniprot id: A0A6P7ZUU9
uniprot id: A0A6P7ZWJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

1415580:LOC115460506
gene id: 1415580:LOC115460506
uniprot id: A0A6P7WSG2
names: Similarity
messages: Belongs to the MS4A family.

1415580:LOC115481883
gene id: 1415580:LOC115481883
uniprot id: A0A6P7ZCT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:NOS3
gene id: 1415580:NOS3
uniprot id: A0A6P7XLC0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NOS family.
messages: Binds 1 FAD.
messages: Binds 1 FMN.
messages: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.

1415580:RBM10
gene id: 1415580:RBM10
uniprot id: A0A6P7ZE60
names: Subcellular Location Annotation
messages: Nucleus

1415580:CSRNP3
gene id: 1415580:CSRNP3
uniprot id: A0A6P7YQ27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

1415580:ZMPSTE24
gene id: 1415580:ZMPSTE24
uniprot id: A0A6P7ZEM5
uniprot id: A0A6P7ZIM7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

1415580:LOC115476995
gene id: 1415580:LOC115476995
uniprot id: A0A6P7YX06
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

1415580:NUDC
gene id: 1415580:NUDC
uniprot id: A0A6P7ZGU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudC family.
messages: Midbody
messages: spindle

1415580:DMTN
gene id: 1415580:DMTN
uniprot id: A0A6P7XR36
uniprot id: A0A6P7XY21
names: Subcellular Location Annotation
messages: Cytoplasm

1415580:HENMT1
gene id: 1415580:HENMT1
uniprot id: A0A6P7YGE0
names: Similarity
messages: Belongs to the methyltransferase superfamily. HEN1 family.

1415580:LOC115457553
gene id: 1415580:LOC115457553
uniprot id: A0A6P7WHW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:MAP2K6
gene id: 1415580:MAP2K6
uniprot id: A0A6P7YBG8
names: Similarity
messages: Belongs to the protein kinase superfamily.

1415580:KAT6A
gene id: 1415580:KAT6A
uniprot id: A0A6P7Y4B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

1415580:CSRNP1
gene id: 1415580:CSRNP1
uniprot id: A0A6P7XTA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

1415580:LOC115476790
gene id: 1415580:LOC115476790
uniprot id: A0A6P7Z0E8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:LOC115480038
gene id: 1415580:LOC115480038
uniprot id: A0A6P7Z9R2
uniprot id: A0A6P7ZFD2
uniprot id: A0A6P7ZFW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFI6/IFI27 family.
messages: Membrane

1415580:LOC115481974
gene id: 1415580:LOC115481974
uniprot id: A0A6P7ZHZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Heterodimer with RPLP1 at the lateral ribosomal stalk of the large ribosomal subunit.
messages: Plays an important role in the elongation step of protein synthesis.

1415580:KDR
gene id: 1415580:KDR
uniprot id: A0A6P7X9J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

1415580:LOC115477307
gene id: 1415580:LOC115477307
uniprot id: A0A6P7YYE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

1415580:LOC115472537
gene id: 1415580:LOC115472537
uniprot id: A0A6P7Y590
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Membrane

1415580:ADAMTS20
gene id: 1415580:ADAMTS20
uniprot id: A0A6P7Z499
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

1415580:LOC115458203
gene id: 1415580:LOC115458203
uniprot id: A0A6P7WU40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:VLDLR
gene id: 1415580:VLDLR
uniprot id: A0A6P7XG95
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: clathrin-coated pit

1415580:GABBR1
gene id: 1415580:GABBR1
uniprot id: A0A6P7XCX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Membrane

1415580:CNN3
gene id: 1415580:CNN3
uniprot id: A0A6P7Y243
uniprot id: A0A6P7Y9E4
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

1415580:LOC115476236
gene id: 1415580:LOC115476236
uniprot id: A0A6P7YTT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apolipoprotein C2 family.
messages: Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase.
messages: Secreted

1415580:LOC115477548
gene id: 1415580:LOC115477548
uniprot id: A0A6P7YT52
names: Subcellular Location Annotation
messages: Membrane

1415580:RIPOR2
gene id: 1415580:RIPOR2
uniprot id: A0A6P7YSS1
uniprot id: A0A6P7YX60
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the RIPOR family.
messages: Cell membrane
messages: Membrane
messages: cytoskeleton
messages: filopodium
messages: stereocilium membrane

1415580:GCNT1
gene id: 1415580:GCNT1
uniprot id: A0A6P7X1Z3
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

1415580:AREG
gene id: 1415580:AREG
uniprot id: A0A6P7X8H2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:B3GNT3
gene id: 1415580:B3GNT3
uniprot id: A0A6P7ZFR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

1415580:SERPINB5
gene id: 1415580:SERPINB5
uniprot id: A0A6P7YK21
names: Similarity
messages: Belongs to the serpin family.

1415580:GGCX
gene id: 1415580:GGCX
uniprot id: A0A6P7Y3D9
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide.
messages: Membrane

1415580:DPYSL4
gene id: 1415580:DPYSL4
uniprot id: A0A6P7Y6R2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

1415580:LOC115481991
gene id: 1415580:LOC115481991
uniprot id: A0A6P7ZDE0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.

1415580:LOC115464570
gene id: 1415580:LOC115464570
uniprot id: A0A6P7XKG7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:MID2
gene id: 1415580:MID2
uniprot id: A0A6P7YK18
names: Subcellular Location Annotation
messages: cytoskeleton

1415580:LOC115480811
gene id: 1415580:LOC115480811
uniprot id: A0A6P7ZLI4
names: Subcellular Location Annotation
messages: Secreted

1415580:LOC115464349
gene id: 1415580:LOC115464349
uniprot id: A0A6P7X4Q2
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

1415580:PHOSPHO1
gene id: 1415580:PHOSPHO1
uniprot id: A0A6P7ZIT2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

1415580:LOC115471181
gene id: 1415580:LOC115471181
uniprot id: A0A6P7Y6Z4
names: Function
messages: May be involved in neurite outgrowth.

1415580:DIS3L2
gene id: 1415580:DIS3L2
uniprot id: A0A6P7YZ91
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation.
messages: Belongs to the RNR ribonuclease family. DIS3L2 subfamily.
messages: Cytoplasm
messages: P-body
messages: Specifically recognizes and binds polyuridylated RNAs via 3 RNA-binding regions (named U-zone 1, U-zone 2 and U-zone 3) that form an open funnel on one face of the catalytic domain, allowing RNA to navigate a path to the active site.

1415580:SMIM22
gene id: 1415580:SMIM22
uniprot id: A0A6P7YXI3
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115457476
gene id: 1415580:LOC115457476
uniprot id: A0A6P7WXW6
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

1415580:PTPN11
gene id: 1415580:PTPN11
uniprot id: A0A6P7ZCM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

1415580:B4GAT1
gene id: 1415580:B4GAT1
uniprot id: A0A6P7ZFM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 49 family.
messages: Golgi apparatus membrane
messages: Membrane

1415580:C1H18orf21
gene id: 1415580:C1H18orf21
uniprot id: A0A6P7YBP2
names: Similarity
messages: Belongs to the UPF0711 family.

1415580:RAG1
gene id: 1415580:RAG1
uniprot id: A0A6P7XIL7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAG1 family.
messages: Binds 1 divalent metal cation per subunit. Mg(2+) or Mn(2+).
messages: Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities. DNA cleavage occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the phosphodiester bond on the opposite strand in a direct transesterification reaction, thereby creating 4 DNA ends: 2 hairpin coding ends and 2 blunt, 5'-phosphorylated ends.
messages: Homodimer.
messages: Nucleus
messages: The NBD (nonamer binding) DNA-binding domain mediates the specific binding to the nonamer RSS motif by forming a tightly interwoven homodimer that binds and synapses 2 nonamer elements, with each NBD making contact with both DNA molecules. Each RSS is composed of well-conserved heptamer (consensus 5'-CACAGTG-3') and nonamer (consensus 5'-ACAAAAACC-3') sequences separated by a spacer of either 12 bp or 23 bp.

1415580:FAM20B
gene id: 1415580:FAM20B
uniprot id: A0A6P7Y8K3
names: Similarity
messages: Belongs to the FAM20 family.

1415580:OLFML2B
gene id: 1415580:OLFML2B
uniprot id: A0A6P7Y7K4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:ARID5B
gene id: 1415580:ARID5B
uniprot id: A0A6P7Y2B8
uniprot id: A0A6P7Y879
names: Similarity
messages: Belongs to the ARID5B family.

1415580:BMP3
gene id: 1415580:BMP3
uniprot id: A0A6P7WTF8
uniprot id: A0A6P7WZ90
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer.
messages: Secreted

1415580:CTNND2
gene id: 1415580:CTNND2
uniprot id: A0A6P7Z818
names: Similarity
messages: Belongs to the beta-catenin family.

1415580:CLSTN2
gene id: 1415580:CLSTN2
uniprot id: A0A6P7Z8I1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Membrane

1415580:LOC115471042
gene id: 1415580:LOC115471042
uniprot id: A0A6P7YBZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

1415580:MAL2
gene id: 1415580:MAL2
uniprot id: A0A6P7Z4K3
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115458145
gene id: 1415580:LOC115458145
uniprot id: A0A6P7WKJ2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LOC115468348
gene id: 1415580:LOC115468348
uniprot id: A0A6P7XTM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Mitochondrion

1415580:LMNB1
gene id: 1415580:LMNB1
uniprot id: A0A6P7XFK4
names: Similarity
messages: Belongs to the intermediate filament family.

1415580:DDX24
gene id: 1415580:DDX24
uniprot id: A0A6P7Z1P0
uniprot id: A0A6P7Z575
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family.
messages: Cytoplasm

1415580:LOC115464246
gene id: 1415580:LOC115464246
uniprot id: A0A6P7XJM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

1415580:GABPA
gene id: 1415580:GABPA
uniprot id: A0A6P7YBB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

1415580:LOC115457125
gene id: 1415580:LOC115457125
uniprot id: A0A6P7WVX9
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115461128
gene id: 1415580:LOC115461128
uniprot id: A0A6P7X8Y6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1415580:CIAO1
gene id: 1415580:CIAO1
uniprot id: A0A6P7XWZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat CIA1 family.
messages: Component of the CIA complex.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins.

1415580:LOC115471354
gene id: 1415580:LOC115471354
uniprot id: A0A6P7Y7G4
names: Similarity
messages: Belongs to the SNF2/RAD54 helicase family.

1415580:RFC5
gene id: 1415580:RFC5
uniprot id: A0A6P7ZJP6
names: Similarity
messages: Belongs to the activator 1 small subunits family.

1415580:DBX2
gene id: 1415580:DBX2
uniprot id: A0A6P7ZC37
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115456986
gene id: 1415580:LOC115456986
uniprot id: A0A6P7WPH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

1415580:LOC115457224
gene id: 1415580:LOC115457224
uniprot id: A0A6P7WW77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115457408
gene id: 1415580:LOC115457408
uniprot id: A0A6P7WWQ8
names: Subcellular Location Annotation
messages: Membrane

1415580:TM2D3
gene id: 1415580:TM2D3
uniprot id: A0A6P7X1M2
uniprot id: A0A6P7X1M7
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115474908
gene id: 1415580:LOC115474908
uniprot id: A0A6P7YN31
names: Similarity
messages: Belongs to the protein kinase superfamily.

1415580:LOC115464486
gene id: 1415580:LOC115464486
uniprot id: A0A6P7XDW4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:ORC4
gene id: 1415580:ORC4
uniprot id: A0A6P7YBQ1
uniprot id: A0A6P7YIT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC4 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication.
messages: Nucleus

1415580:FLVCR2
gene id: 1415580:FLVCR2
uniprot id: A0A6P7YT29
names: Subcellular Location Annotation
messages: Membrane

1415580:LPL
gene id: 1415580:LPL
uniprot id: A0A6P7XAM7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Cell membrane
messages: Homodimer. Interacts with APOC2; the interaction activates LPL activity in the presence of lipids.
messages: Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Tyrosine nitration after lipopolysaccharide (LPS) challenge down-regulates the lipase activity.
messages: extracellular matrix

1415580:HAAO
gene id: 1415580:HAAO
uniprot id: A0A6P7XEL5
uniprot id: A0A6P7XLV0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 3-HAO family.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1415580:ANKS1A
gene id: 1415580:ANKS1A
uniprot id: A0A6P7ZAE6
uniprot id: A0A6P7ZEU1
uniprot id: A0A6P7ZEU6
uniprot id: A0A6P7ZLR6
uniprot id: A0A6P7ZLS8
uniprot id: A0A6P7ZQ05
uniprot id: A0A6P7ZQ12
uniprot id: A0A6P7ZSC9
names: Subcellular Location Annotation
messages: Cytoplasm

1415580:TM2D2
gene id: 1415580:TM2D2
uniprot id: A0A6P7XQU9
names: Subcellular Location Annotation
messages: Membrane

1415580:ATG16L1
gene id: 1415580:ATG16L1
uniprot id: A0A6P7ZBL4
names: Similarity
messages: Belongs to the WD repeat ATG16 family.

1415580:LOC115480164
gene id: 1415580:LOC115480164
uniprot id: A0A6P7ZFZ9
names: Similarity
messages: Belongs to the cytochrome P450 family.

1415580:LOC115462035
gene id: 1415580:LOC115462035
uniprot id: A0A6P7WXI4
names: Subcellular Location Annotation
messages: Nucleus

1415580:FGD1
gene id: 1415580:FGD1
uniprot id: A0A6P7X3H5
uniprot id: A0A6P7XC84
names: Subcellular Location Annotation
messages: cytoskeleton

1415580:GASK1B
gene id: 1415580:GASK1B
uniprot id: A0A6P7WW91
names: Similarity
messages: Belongs to the GASK family.

1415580:PMEPA1
gene id: 1415580:PMEPA1
uniprot id: A0A6P7YPC6
uniprot id: A0A6P7YX75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMEPA1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

1415580:DAPK3
gene id: 1415580:DAPK3
uniprot id: A0A6P7Z7B7
names: Similarity
messages: Belongs to the protein kinase superfamily.

1415580:LOC115464738
gene id: 1415580:LOC115464738
uniprot id: A0A6P7XEN3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:TTN
gene id: 1415580:TTN
uniprot id: A0A6P7YNV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cell membrane

1415580:LOC115474255
gene id: 1415580:LOC115474255
uniprot id: A0A6P7YL28
uniprot id: A0A6P7YQH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sesquipedalian family.
messages: Early endosome
messages: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
messages: Recycling endosome
messages: clathrin-coated vesicle
messages: trans-Golgi network

1415580:PRDM15
gene id: 1415580:PRDM15
uniprot id: A0A6P7XW64
uniprot id: A0A6P7Y3I5
uniprot id: A0A6P7Y9A3
names: Subcellular Location Annotation
messages: Nucleus

1415580:AP1S1
gene id: 1415580:AP1S1
uniprot id: A0A6P7WZ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

1415580:LOC115469712
gene id: 1415580:LOC115469712
uniprot id: A0A6P7Y6I8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115461989
gene id: 1415580:LOC115461989
uniprot id: A0A6P7X5Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115457791
gene id: 1415580:LOC115457791
uniprot id: A0A6P7WZA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DAD/OST2 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

1415580:LOC115474766
gene id: 1415580:LOC115474766
uniprot id: A0A6P7YMN0
names: Similarity
messages: Belongs to the globin family.

1415580:AQP8
gene id: 1415580:AQP8
uniprot id: A0A6P7YT79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1415580:LOC115476607
gene id: 1415580:LOC115476607
uniprot id: A0A6P7YNQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

1415580:ATP6AP2
gene id: 1415580:ATP6AP2
uniprot id: A0A6P7Y620
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Lysosome membrane
messages: Membrane
messages: autophagosome membrane
messages: clathrin-coated vesicle membrane
messages: dendritic spine membrane
messages: synaptic vesicle membrane

1415580:DPY19L4
gene id: 1415580:DPY19L4
uniprot id: A0A6P7ZB35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

1415580:LOC115481871
gene id: 1415580:LOC115481871
uniprot id: A0A6P7ZUQ0
names: Similarity
messages: Belongs to the RIB43A family.

1415580:CDX2
gene id: 1415580:CDX2
uniprot id: A0A6P7Y681
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

1415580:LOC115466290
gene id: 1415580:LOC115466290
uniprot id: A0A6P7XRP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

1415580:FITM2
gene id: 1415580:FITM2
uniprot id: A0A6P7YIG6
uniprot id: A0A6P7YP11
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:PPP1R16B
gene id: 1415580:PPP1R16B
uniprot id: A0A6P7YQE8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LOC115466543
gene id: 1415580:LOC115466543
uniprot id: A0A6P7XTC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 11 family.
messages: Golgi stack membrane
messages: Membrane

1415580:HSPB6
gene id: 1415580:HSPB6
uniprot id: A0A6P7YZB3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1415580:NKX2-6
gene id: 1415580:NKX2-6
uniprot id: A0A6P7Y0M3
names: Subcellular Location Annotation
messages: Nucleus

1415580:DHH
gene id: 1415580:DHH
uniprot id: A0A6P7XF52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

1415580:LOC115481601
gene id: 1415580:LOC115481601
uniprot id: A0A6P7ZNZ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

1415580:ACAN
gene id: 1415580:ACAN
uniprot id: A0A6P7WQT0
uniprot id: A0A6P7WWP0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aggrecan/versican proteoglycan family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

1415580:UTS2R
gene id: 1415580:UTS2R
uniprot id: A0A6P7YLK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
messages: Membrane

1415580:CHCHD4
gene id: 1415580:CHCHD4
uniprot id: A0A6P7Y9A2
names: Subcellular Location Annotation
messages: Mitochondrion intermembrane space

1415580:LOC115465794
gene id: 1415580:LOC115465794
uniprot id: A0A6P7X9V8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROX family. NO66 subfamily.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.
messages: nucleolus

1415580:GLDC
gene id: 1415580:GLDC
uniprot id: A0A6P7XAX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvP family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1415580:LOC115473950
gene id: 1415580:LOC115473950
uniprot id: A0A6P7YPK5
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

1415580:LOC115460542
gene id: 1415580:LOC115460542
uniprot id: A0A6P7WSK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115457173
gene id: 1415580:LOC115457173
uniprot id: A0A6P7WN28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:KIN
gene id: 1415580:KIN
uniprot id: A0A6P7Z804
names: Similarity
messages: Belongs to the KIN17 family.

1415580:LOC115457419
gene id: 1415580:LOC115457419
uniprot id: A0A6P7WQQ4
names: Subcellular Location Annotation
messages: Membrane

1415580:IER3IP1
gene id: 1415580:IER3IP1
uniprot id: A0A6P7WZS6
names: Similarity
messages: Belongs to the YOS1 family.

1415580:KCNJ14
gene id: 1415580:KCNJ14
uniprot id: A0A6P7XDF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

1415580:SRF
gene id: 1415580:SRF
uniprot id: A0A6P7XEC0
uniprot id: A0A6P7XLL2
names: Subcellular Location Annotation
messages: Nucleus

1415580:ZDHHC4
gene id: 1415580:ZDHHC4
uniprot id: A0A6P7YQF1
uniprot id: A0A6P7YY68
uniprot id: A0A6P7Z1Y9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

1415580:RAD52
gene id: 1415580:RAD52
uniprot id: A0A6P7Z164
uniprot id: A0A6P7Z2N0
uniprot id: A0A6P7Z5G3
names: Similarity
messages: Belongs to the RAD52 family.

1415580:PPP2R5B
gene id: 1415580:PPP2R5B
uniprot id: A0A6P7Z2P6
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

1415580:PRPS2
gene id: 1415580:PRPS2
uniprot id: A0A6P7Y3N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.

1415580:LOC115479717
gene id: 1415580:LOC115479717
uniprot id: A0A6P7Z309
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1415580:AATF
gene id: 1415580:AATF
uniprot id: A0A6P7WEE4
names: Similarity
messages: Belongs to the AATF family.

1415580:SIM1
gene id: 1415580:SIM1
uniprot id: A0A6P7XMC6
names: Subcellular Location Annotation
messages: Nucleus

1415580:KCNK7
gene id: 1415580:KCNK7
uniprot id: A0A6P7ZE33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: Recycling endosome
messages: Synaptic cell membrane
messages: Vesicle
messages: dendrite

1415580:GLI3
gene id: 1415580:GLI3
uniprot id: A0A6P7Y489
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Cytoplasm
messages: Nucleus

1415580:NUMB
gene id: 1415580:NUMB
uniprot id: A0A6P7YQX0
uniprot id: A0A6P7YXK2
uniprot id: A0A6P7YXK7
uniprot id: A0A6P7Z2I2
names: Function
messages: Plays a role in the process of neurogenesis.

1415580:MAP4K2
gene id: 1415580:MAP4K2
uniprot id: A0A6P7ZDN0
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

1415580:LOC115481147
gene id: 1415580:LOC115481147
uniprot id: A0A6P7ZJX7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1415580:LOC115477109
gene id: 1415580:LOC115477109
uniprot id: A0A6P7YXC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

1415580:TRAPPC2
gene id: 1415580:TRAPPC2
uniprot id: A0A6P7Y356
uniprot id: A0A6P7Y3M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

1415580:LOC115481127
gene id: 1415580:LOC115481127
uniprot id: A0A6P7ZE02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Membrane
messages: Microsome membrane

1415580:LOC115473772
gene id: 1415580:LOC115473772
uniprot id: A0A6P7YIJ9
uniprot id: A0A6P7YNF1
uniprot id: A0A6P7YNU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

1415580:LOC115471190
gene id: 1415580:LOC115471190
uniprot id: A0A6P7Y6Y5
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations.
messages: Secreted

1415580:LOC115457916
gene id: 1415580:LOC115457916
uniprot id: A0A6P7WZZ7
names: Subcellular Location Annotation
messages: Membrane

1415580:JAK1
gene id: 1415580:JAK1
uniprot id: A0A6P7YJY3
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.

1415580:WNT10B
gene id: 1415580:WNT10B
uniprot id: A0A6P7XAR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

1415580:FADS6
gene id: 1415580:FADS6
uniprot id: A0A6P7YMA3
names: Similarity
messages: Belongs to the fatty acid desaturase type 1 family.

1415580:LOC115471570
gene id: 1415580:LOC115471570
uniprot id: A0A6P7Y7Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

1415580:TOR2A
gene id: 1415580:TOR2A
uniprot id: A0A6P7YFK4
uniprot id: A0A6P7YLC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.
messages: Endoplasmic reticulum lumen

1415580:ELK4
gene id: 1415580:ELK4
uniprot id: A0A6P7ZUP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

1415580:LOC115473270
gene id: 1415580:LOC115473270
uniprot id: A0A6P7YLE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

1415580:CACFD1
gene id: 1415580:CACFD1
uniprot id: A0A6P7YF54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel flower family.
messages: Membrane

1415580:SNX17
gene id: 1415580:SNX17
uniprot id: A0A6P7XFZ3
uniprot id: A0A6P7XMV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane
messages: Early endosome
messages: Endosome
messages: Membrane

1415580:LOC115475066
gene id: 1415580:LOC115475066
uniprot id: A0A6P7YPL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Cytoplasm
messages: Nucleus
messages: Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.

1415580:CAP1
gene id: 1415580:CAP1
uniprot id: A0A6P7ZGH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CAP family.
messages: Cell membrane
messages: Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity.
messages: Homodimer. Binds actin monomers.
messages: Membrane

1415580:LOC115474763
gene id: 1415580:LOC115474763
uniprot id: A0A6P7YSN2
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

1415580:FGF10
gene id: 1415580:FGF10
uniprot id: A0A6P7X0B7
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

1415580:PRKCI
gene id: 1415580:PRKCI
uniprot id: A0A6P7Z8H5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

1415580:DLGAP1
gene id: 1415580:DLGAP1
uniprot id: A0A6P7YWL6
uniprot id: A0A6P7YZQ7
names: Similarity
messages: Belongs to the SAPAP family.

1415580:LOC115476361
gene id: 1415580:LOC115476361
uniprot id: A0A6P7YYJ8
uniprot id: A0A6P7YZ46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TYROBP family.
messages: Cell membrane
messages: Membrane

1415580:LOC115469714
gene id: 1415580:LOC115469714
uniprot id: A0A6P7Y5I0
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

1415580:LOC115481209
gene id: 1415580:LOC115481209
uniprot id: A0A6P7ZRM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

1415580:NUP58
gene id: 1415580:NUP58
uniprot id: A0A6P7XZM3
names: Subcellular Location Annotation
messages: nuclear pore complex

1415580:POMT2
gene id: 1415580:POMT2
uniprot id: A0A6P7YQS2
uniprot id: A0A6P7YXG1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

1415580:GGT5
gene id: 1415580:GGT5
uniprot id: A0A6P7ZEZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

1415580:CA7
gene id: 1415580:CA7
uniprot id: A0A6P7Y5R7
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1415580:NDUFS2
gene id: 1415580:NDUFS2
uniprot id: A0A6P7X081
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

1415580:TRMT10C
gene id: 1415580:TRMT10C
uniprot id: A0A6P7Y003
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

1415580:VDR
gene id: 1415580:VDR
uniprot id: A0A6P7XN90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Cytoplasm
messages: Nucleus

1415580:OSBPL2
gene id: 1415580:OSBPL2
uniprot id: A0A6P7YY41
uniprot id: A0A6P7Z111
uniprot id: A0A6P7Z1W1
names: Similarity
messages: Belongs to the OSBP family.

1415580:LOC115457020
gene id: 1415580:LOC115457020
uniprot id: A0A6P7WWL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:RPN2
gene id: 1415580:RPN2
uniprot id: A0A6P7YKD7
uniprot id: A0A6P7YSH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SWP1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

1415580:SMG9
gene id: 1415580:SMG9
uniprot id: A0A6P7YU76
uniprot id: A0A6P7YYH3
names: Similarity
messages: Belongs to the SMG9 family.

1415580:KIF5B
gene id: 1415580:KIF5B
uniprot id: A0A6P7XHN4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

1415580:LOC115479154
gene id: 1415580:LOC115479154
uniprot id: A0A6P7Z5R1
names: Similarity
messages: Belongs to the cytochrome P450 family.

1415580:EFNA2
gene id: 1415580:EFNA2
uniprot id: A0A6P7ZBJ2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:LOC115464964
gene id: 1415580:LOC115464964
uniprot id: A0A6P7XDA4
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

1415580:TCTN2
gene id: 1415580:TCTN2
uniprot id: A0A6P7Z2G4
uniprot id: A0A6P7ZAC7
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

1415580:VAMP8
gene id: 1415580:VAMP8
uniprot id: A0A6P7XQ87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

1415580:CACNG8
gene id: 1415580:CACNG8
uniprot id: A0A6P7XDM7
uniprot id: A0A6P7XM77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits.

1415580:SLC7A11
gene id: 1415580:SLC7A11
uniprot id: A0A6P7XAJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Membrane

1415580:EPN2
gene id: 1415580:EPN2
uniprot id: A0A6P7YMA1
uniprot id: A0A6P7YU41
uniprot id: A0A6P7YV18
uniprot id: A0A6P7YYD4
uniprot id: A0A6P7YYY9
names: Similarity
messages: Belongs to the epsin family.

1415580:SLC25A46
gene id: 1415580:SLC25A46
uniprot id: A0A6P7X7P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion outer membrane

1415580:LOC115458204
gene id: 1415580:LOC115458204
uniprot id: A0A6P7X063
names: Subcellular Location Annotation
messages: Membrane

1415580:MRPS31
gene id: 1415580:MRPS31
uniprot id: A0A6P7XXS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS31 family.
messages: Mitochondrion

1415580:GTF2A2
gene id: 1415580:GTF2A2
uniprot id: A0A6P7WVE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 2 family.
messages: Nucleus
messages: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation.

1415580:AVPR2
gene id: 1415580:AVPR2
uniprot id: A0A6P7X303
uniprot id: A0A6P7XH07
uniprot id: A0A6P7XI40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

1415580:LOC115457050
gene id: 1415580:LOC115457050
uniprot id: A0A6P7WWP6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:HCN2
gene id: 1415580:HCN2
uniprot id: A0A6P7Z656
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

1415580:B4GALT7
gene id: 1415580:B4GALT7
uniprot id: A0A6P7Z0L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

1415580:MATK
gene id: 1415580:MATK
uniprot id: A0A6P7Z9L6
uniprot id: A0A6P7ZFS1
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

1415580:LOC115469916
gene id: 1415580:LOC115469916
uniprot id: A0A6P7Y614
names: Subcellular Location Annotation
messages: Nucleus

1415580:USP37
gene id: 1415580:USP37
uniprot id: A0A6P7YII1
uniprot id: A0A6P7YND8
uniprot id: A0A6P7YNT1
names: Similarity
messages: Belongs to the peptidase C19 family.

1415580:SUSD2
gene id: 1415580:SUSD2
uniprot id: A0A6P7ZRC0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115476673
gene id: 1415580:LOC115476673
uniprot id: A0A6P7YP19
uniprot id: A0A6P7YWT5
names: Subcellular Location Annotation
messages: Secreted

1415580:PDE3B
gene id: 1415580:PDE3B
uniprot id: A0A6P7XNH5
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

1415580:KCNH2
gene id: 1415580:KCNH2
uniprot id: A0A6P7XM93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv11.1/KCNH2 sub-subfamily.
messages: Membrane

1415580:LOC115480407
gene id: 1415580:LOC115480407
uniprot id: A0A6P7ZIP1
names: Similarity
messages: Belongs to the GCN1 family.

1415580:CLCN2
gene id: 1415580:CLCN2
uniprot id: A0A6P7YZ14
uniprot id: A0A6P7Z6W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-2/CLCN2 subfamily.
messages: Cell membrane
messages: Membrane

1415580:LOC115462486
gene id: 1415580:LOC115462486
uniprot id: A0A6P7XCL3
names: Subcellular Location Annotation
messages: Nucleus

1415580:SLC16A2
gene id: 1415580:SLC16A2
uniprot id: A0A6P7YKZ6
names: Subcellular Location Annotation
messages: Membrane

1415580:FGF5
gene id: 1415580:FGF5
uniprot id: A0A6P7WYM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heparin-binding growth factors family.
messages: Interacts with FGFR1 and FGFR2. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors.
messages: Plays an important role in the regulation of cell proliferation and cell differentiation. Required for normal regulation of the hair growth cycle. Functions as an inhibitor of hair elongation by promoting progression from anagen, the growth phase of the hair follicle, into catagen the apoptosis-induced regression phase.
messages: Secreted

1415580:SGCZ
gene id: 1415580:SGCZ
uniprot id: A0A6P7X7T2
uniprot id: A0A6P7XE74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

1415580:LOC115458135
gene id: 1415580:LOC115458135
uniprot id: A0A6P7WKI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:ROR2
gene id: 1415580:ROR2
uniprot id: A0A6P7XFN6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:NCAPG
gene id: 1415580:NCAPG
uniprot id: A0A6P7X943
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND3 (condensin subunit 3) family.
messages: Chromosome

1415580:HOXC5
gene id: 1415580:HOXC5
uniprot id: A0A6P7XUQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

1415580:LOC115471792
gene id: 1415580:LOC115471792
uniprot id: A0A6P7Y964
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

1415580:LOC115457396
gene id: 1415580:LOC115457396
uniprot id: A0A6P7WQM5
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115469357
gene id: 1415580:LOC115469357
uniprot id: A0A6P7XYV4
uniprot id: A0A6P7Y4T8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LPGAT1
gene id: 1415580:LPGAT1
uniprot id: A0A6P7X8K9
uniprot id: A0A6P7XFF9
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

1415580:LOC115476904
gene id: 1415580:LOC115476904
uniprot id: A0A6P7Z1K9
names: Similarity
messages: Belongs to the SNF7 family.

1415580:LOC115458237
gene id: 1415580:LOC115458237
uniprot id: A0A6P7WKT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115468223
gene id: 1415580:LOC115468223
uniprot id: A0A6P7XJE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane
messages: Photoreceptor outer segment membrane

1415580:LOC115474244
gene id: 1415580:LOC115474244
uniprot id: A0A6P7YQS9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1415580:LOC115481769
gene id: 1415580:LOC115481769
uniprot id: A0A6P7ZV52
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.

1415580:FLT1
gene id: 1415580:FLT1
uniprot id: A0A6P7XUL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

1415580:HOXB4
gene id: 1415580:HOXB4
uniprot id: A0A6P7ZUB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

1415580:USP33
gene id: 1415580:USP33
uniprot id: A0A6P7Y8Z4
uniprot id: A0A6P7YFZ3
uniprot id: A0A6P7YGA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP20/USP33 subfamily.
messages: centrosome
messages: perinuclear region

1415580:HOXB9
gene id: 1415580:HOXB9
uniprot id: A0A6P7ZW79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

1415580:LOC115478359
gene id: 1415580:LOC115478359
uniprot id: A0A6P7Z4E3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:FUZ
gene id: 1415580:FUZ
uniprot id: A0A6P7XKU9
uniprot id: A0A6P7XLS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fuzzy family.
messages: cytoskeleton

1415580:KIF21B
gene id: 1415580:KIF21B
uniprot id: A0A6P7ZVL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

1415580:LYRM7
gene id: 1415580:LYRM7
uniprot id: A0A6P7X1M3
uniprot id: A0A6P7XAC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.
messages: Belongs to the complex I LYR family.
messages: Interacts with UQCRFS1.
messages: Mitochondrion matrix

1415580:LOC115477556
gene id: 1415580:LOC115477556
uniprot id: A0A6P7Z3Q5
uniprot id: A0A6P7Z4F0
names: Similarity
messages: Belongs to the aldo/keto reductase family.

1415580:DCPS
gene id: 1415580:DCPS
uniprot id: A0A6P7ZVU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HIT family.
messages: Cytoplasm
messages: Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway.
messages: Homodimer. Associates with components of the exosome multienzyme ribonuclease complex, such as EXOSC3 and EXOSC4. Interacts with NDOR1.
messages: Nucleus

1415580:PPP3CC
gene id: 1415580:PPP3CC
uniprot id: A0A6P7XR75
uniprot id: A0A6P7XY62
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

1415580:CRYAB
gene id: 1415580:CRYAB
uniprot id: A0A6P7ZFJ1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1415580:LOC115457163
gene id: 1415580:LOC115457163
uniprot id: A0A6P7WPZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:E2F1
gene id: 1415580:E2F1
uniprot id: A0A6P7YXK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

1415580:CEP162
gene id: 1415580:CEP162
uniprot id: A0A6P7XHM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP162 family.
messages: centriole

1415580:NCAPD2
gene id: 1415580:NCAPD2
uniprot id: A0A6P7X0T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND1 (condensin subunit 1) family.
messages: Chromosome
messages: Nucleus
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

1415580:LOC115480962
gene id: 1415580:LOC115480962
uniprot id: A0A6P7ZIA7
names: Similarity
messages: Belongs to the histone H2B family.
messages: Belongs to the histone H3 family.

1415580:LOC115458248
gene id: 1415580:LOC115458248
uniprot id: A0A6P7WS11
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LOC115477771
gene id: 1415580:LOC115477771
uniprot id: A0A6P7YU49
uniprot id: A0A6P7Z0G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1415580:CASP9
gene id: 1415580:CASP9
uniprot id: A0A6P7WN69
uniprot id: A0A6P7WU77
names: Similarity
messages: Belongs to the peptidase C14A family.

1415580:BBOX1
gene id: 1415580:BBOX1
uniprot id: A0A6P7Y152
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-BBH/TMLD family.
messages: Catalyzes the formation of L-carnitine from gamma-butyrobetaine.
messages: Cytoplasm

1415580:LOC115458434
gene id: 1415580:LOC115458434
uniprot id: A0A6P7WSU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:DUS3L
gene id: 1415580:DUS3L
uniprot id: A0A6P7XKC5
uniprot id: A0A6P7XKD6
names: Similarity
messages: Belongs to the dus family. Dus3 subfamily.

1415580:LOC115461965
gene id: 1415580:LOC115461965
uniprot id: A0A6P7X3B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:DHDDS
gene id: 1415580:DHDDS
uniprot id: A0A6P7ZIZ0
names: Similarity
messages: Belongs to the UPP synthase family.

1415580:MOK
gene id: 1415580:MOK
uniprot id: A0A6P7Z120
uniprot id: A0A6P7Z4K6
names: Similarity
messages: Belongs to the protein kinase superfamily.

1415580:ANXA10
gene id: 1415580:ANXA10
uniprot id: A0A6P7X254
names: Similarity
messages: Belongs to the annexin family.

1415580:LOC115464399
gene id: 1415580:LOC115464399
uniprot id: A0A6P7X4V6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LOC115476448
gene id: 1415580:LOC115476448
uniprot id: A0A6P7YMX7
uniprot id: A0A6P7YVN3
names: Subcellular Location Annotation
messages: Nucleus

1415580:PRR5
gene id: 1415580:PRR5
uniprot id: A0A6P7YSJ3
uniprot id: A0A6P7YYZ9
uniprot id: A0A6P7YZ03
uniprot id: A0A6P7Z340
uniprot id: A0A6P7Z3W6
names: Similarity
messages: Belongs to the PROTOR family.

1415580:ASPHD2
gene id: 1415580:ASPHD2
uniprot id: A0A6P7ZNH7
names: Similarity
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.

1415580:LOC115466814
gene id: 1415580:LOC115466814
uniprot id: A0A6P7XM00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

1415580:LOC115475104
gene id: 1415580:LOC115475104
uniprot id: A0A6P7YTV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

1415580:LOC115465793
gene id: 1415580:LOC115465793
uniprot id: A0A6P7XGS4
names: Similarity
messages: Belongs to the zygin family.

1415580:DLL1
gene id: 1415580:DLL1
uniprot id: A0A6P7X8C9
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

1415580:LOC115468786
gene id: 1415580:LOC115468786
uniprot id: A0A6P7XUH7
uniprot id: A0A6P7XVU3
uniprot id: A0A6P7Y1D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
messages: Peroxisome

1415580:FAM13C
gene id: 1415580:FAM13C
uniprot id: A0A6P7YCC0
names: Similarity
messages: Belongs to the FAM13 family.

1415580:PPP1R14B
gene id: 1415580:PPP1R14B
uniprot id: A0A6P7Z713
names: Similarity
messages: Belongs to the PP1 inhibitor family.

1415580:TMEM35B
gene id: 1415580:TMEM35B
uniprot id: A0A6P7ZAN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1415580:PRUNE1
gene id: 1415580:PRUNE1
uniprot id: A0A6P7WZL7
names: Similarity
messages: Belongs to the PPase class C family. Prune subfamily.

1415580:SH3BGRL
gene id: 1415580:SH3BGRL
uniprot id: A0A6P7YPN8
names: Similarity
messages: Belongs to the SH3BGR family.

1415580:TMEM161B
gene id: 1415580:TMEM161B
uniprot id: A0A6P7XEZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM161 family.
messages: Membrane

1415580:LOC115480965
gene id: 1415580:LOC115480965
uniprot id: A0A6P7X5J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1415580:LOC115477135
gene id: 1415580:LOC115477135
uniprot id: A0A6P7Z2E6
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

1415580:AARSD1
gene id: 1415580:AARSD1
uniprot id: A0A6P7ZTF2
uniprot id: A0A6P7ZUW0
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.

1415580:LOC115457195
gene id: 1415580:LOC115457195
uniprot id: A0A6P7WW47
names: Subcellular Location Annotation
messages: Membrane

1415580:RETREG1
gene id: 1415580:RETREG1
uniprot id: A0A6P7Y6I6
uniprot id: A0A6P7Y6J5
uniprot id: A0A6P7YDX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RETREG family.
messages: Membrane

1415580:MFSD6
gene id: 1415580:MFSD6
uniprot id: A0A6P7YGK4
uniprot id: A0A6P7YTI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. MFSD6 family.
messages: Membrane

1415580:DDOST
gene id: 1415580:DDOST
uniprot id: A0A6P7WLR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDOST 48 kDa subunit family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).

1415580:HTR1A
gene id: 1415580:HTR1A
uniprot id: A0A6P7XB60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:IPMK
gene id: 1415580:IPMK
uniprot id: A0A6P7Y758
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

1415580:CTSD
gene id: 1415580:CTSD
uniprot id: A0A6P7XVU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Lysosome

1415580:ADSL
gene id: 1415580:ADSL
uniprot id: A0A6P7YNU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

1415580:FBXL5
gene id: 1415580:FBXL5
uniprot id: A0A6P7WV74
names: Subcellular Location Annotation
messages: perinuclear region

1415580:POMC
gene id: 1415580:POMC
uniprot id: A0A6P7XG22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POMC family.
messages: Endogenous opiate.
messages: Secreted
messages: Stimulates the adrenal glands to release cortisol.

1415580:LOC115464649
gene id: 1415580:LOC115464649
uniprot id: A0A6P7XKN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:SOGA3
gene id: 1415580:SOGA3
uniprot id: A0A6P7XHQ0
names: Similarity
messages: Belongs to the SOGA family.

1415580:GFRA4
gene id: 1415580:GFRA4
uniprot id: A0A6P7X325
uniprot id: A0A6P7X9R6
names: Similarity
messages: Belongs to the GDNFR family.

1415580:CCKBR
gene id: 1415580:CCKBR
uniprot id: A0A6P7XYN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115465972
gene id: 1415580:LOC115465972
uniprot id: A0A6P7XPY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

1415580:ALKBH5
gene id: 1415580:ALKBH5
uniprot id: A0A6P7YUH0
names: Subcellular Location Annotation
names: Subunit
messages: Monomer.
messages: Nucleus speckle

1415580:LOC115457988
gene id: 1415580:LOC115457988
uniprot id: A0A6P7X0B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

1415580:TAF9B
gene id: 1415580:TAF9B
uniprot id: A0A6P7YRN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

1415580:MTNR1B
gene id: 1415580:MTNR1B
uniprot id: A0A6P7XRA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:FAM199X
gene id: 1415580:FAM199X
uniprot id: A0A6P7YP21
names: Similarity
messages: Belongs to the FAM199 family.

1415580:IRF3
gene id: 1415580:IRF3
uniprot id: A0A6P7XMU3
uniprot id: A0A6P7XTT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Nucleus

1415580:HOXA6
gene id: 1415580:HOXA6
uniprot id: A0A6P7Y687
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

1415580:C8G
gene id: 1415580:C8G
uniprot id: A0A6P7YCX2
uniprot id: A0A6P7YI95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

1415580:DNASE1L3
gene id: 1415580:DNASE1L3
uniprot id: A0A6P7Y4J2
names: Similarity
messages: Belongs to the DNase I family.

1415580:SYT14
gene id: 1415580:SYT14
uniprot id: A0A6P7XNH1
names: Similarity
messages: Belongs to the synaptotagmin family.

1415580:NDRG3
gene id: 1415580:NDRG3
uniprot id: A0A6P7YNC4
uniprot id: A0A6P7YV17
uniprot id: A0A6P7YZB7
names: Similarity
messages: Belongs to the NDRG family.

1415580:REXO4
gene id: 1415580:REXO4
uniprot id: A0A6P7YKF3
names: Similarity
messages: Belongs to the REXO4 family.

1415580:LOC115461902
gene id: 1415580:LOC115461902
uniprot id: A0A6P7X5R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

1415580:NASP
gene id: 1415580:NASP
uniprot id: A0A6P7Y3J5
uniprot id: A0A6P7YAW6
uniprot id: A0A6P7YG54
uniprot id: A0A6P7YGR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NASP family.
messages: Nucleus

1415580:SF3B1
gene id: 1415580:SF3B1
uniprot id: A0A6P7YKZ2
uniprot id: A0A6P7YLJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B1 family.
messages: Nucleus

1415580:PSMD1
gene id: 1415580:PSMD1
uniprot id: A0A6P7YX02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S1 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

1415580:HMGN1
gene id: 1415580:HMGN1
uniprot id: A0A6P7XW85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

1415580:CABIN1
gene id: 1415580:CABIN1
uniprot id: A0A6P7Z9F9
uniprot id: A0A6P7ZF24
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115482526
gene id: 1415580:LOC115482526
uniprot id: A0A6P7ZFX4
names: Similarity
messages: Belongs to the peptidase C1 family.

1415580:ADGRD1
gene id: 1415580:ADGRD1
uniprot id: A0A6P7Z7N4
uniprot id: A0A6P7ZCF2
uniprot id: A0A6P7ZG69
names: Subcellular Location Annotation
messages: Membrane

1415580:SLC27A2
gene id: 1415580:SLC27A2
uniprot id: A0A6P7WWE0
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

1415580:ATP5F1E
gene id: 1415580:ATP5F1E
uniprot id: A0A6P7YZ62
names: Function
names: Similarity
messages: Belongs to the eukaryotic ATPase epsilon family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

1415580:LSM1
gene id: 1415580:LSM1
uniprot id: A0A6P7XSJ8
uniprot id: A0A6P7XYF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Cytoplasm
messages: LSm subunits form a heteromer with a donut shape.
messages: P-body
messages: Probably involved with other LSm subunits in the general process of degradation of mRNAs.

1415580:KCNK12
gene id: 1415580:KCNK12
uniprot id: A0A6P7XIF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

1415580:IER5L
gene id: 1415580:IER5L
uniprot id: A0A6P7YH87
names: Similarity
messages: Belongs to the IER family.

1415580:NIPBL
gene id: 1415580:NIPBL
uniprot id: A0A6P7XCA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC2/Nipped-B family.
messages: Nucleus

1415580:ESYT2
gene id: 1415580:ESYT2
uniprot id: A0A6P7XGF1
uniprot id: A0A6P7XGF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the extended synaptotagmin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:LOC115464521
gene id: 1415580:LOC115464521
uniprot id: A0A6P7XJC2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:PIGZ
gene id: 1415580:PIGZ
uniprot id: A0A6P7YBX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:PAN3
gene id: 1415580:PAN3
uniprot id: A0A6P7XLC5
uniprot id: A0A6P7XUL0
uniprot id: A0A6P7XZP3
uniprot id: A0A6P7Y072
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. PAN3 family.
messages: Contains a pseudokinase domain. The protein kinase domain is predicted to be catalytically inactive because some of the residues important for catalytic activity are substituted and it lacks the equivalent of the binding site for a peptide substrate. However, it has retained an ATP-binding site and ATP-binding is required for mRNA degradation, stimulating the activity of the PAN2 nuclease in vitro. The nucleotide-binding site is juxtaposed to the RNase active site of PAN2 in the complex and may actually bind nucleosides of a poly(A) RNA rather than ATP, feeding the poly(A)-tail to the active site of the deadenylase and thus increasing the efficiency with which this distributive enzyme degrades oligo(A) RNAs.
messages: Homodimer. Forms a heterotrimer with a catalytic subunit PAN2 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts (via PAM-2 motif) with poly(A)-binding protein PABPC1 (via PABC domain), conferring substrate specificity of the enzyme complex. Interacts with the GW182 family proteins TNRC6A, TNRC6B and TNRC6C.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: P-body
messages: Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and PABP, and to miRNA targets via its interaction with GW182 family proteins.
messages: The N-terminal zinc finger binds to poly(A) RNA.
messages: The pseudokinase domain, the coiled-coil (CC), and C-terminal knob domain (CK) form a structural unit (PKC) that forms an extensive high-affinity interaction surface for PAN2.

1415580:GPATCH1
gene id: 1415580:GPATCH1
uniprot id: A0A6P7XY02
uniprot id: A0A6P7Y5Q7
names: Similarity
messages: Belongs to the GPATCH1 family.

1415580:ILKAP
gene id: 1415580:ILKAP
uniprot id: A0A6P7YX41
uniprot id: A0A6P7Z4Y1
uniprot id: A0A6P7Z4Y9
uniprot id: A0A6P7Z8D6
names: Similarity
messages: Belongs to the PP2C family.

1415580:SCARB2
gene id: 1415580:SCARB2
uniprot id: A0A6P7X1T6
names: Similarity
messages: Belongs to the CD36 family.

1415580:CELF1
gene id: 1415580:CELF1
uniprot id: A0A6P7XN63
uniprot id: A0A6P7XWA5
uniprot id: A0A6P7Y1T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

1415580:USP2
gene id: 1415580:USP2
uniprot id: A0A6P7ZRW4
names: Similarity
messages: Belongs to the peptidase C19 family.

1415580:G6PC3
gene id: 1415580:G6PC3
uniprot id: A0A6P7ZPN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

1415580:IL12A
gene id: 1415580:IL12A
uniprot id: A0A6P7Z724
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-6 superfamily.
messages: Heterodimer with IL12B; disulfide-linked. The heterodimer is known as interleukin IL-12.
messages: Secreted

1415580:LOC115481899
gene id: 1415580:LOC115481899
uniprot id: A0A6P7ZHB7
uniprot id: A0A6P7ZVH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:SLC1A2
gene id: 1415580:SLC1A2
uniprot id: A0A6P7XS49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1415580:ETV7
gene id: 1415580:ETV7
uniprot id: A0A6P7ZGI8
uniprot id: A0A6P7ZQT6
uniprot id: A0A6P7ZUA3
uniprot id: A0A6P7ZV64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

1415580:SBNO2
gene id: 1415580:SBNO2
uniprot id: A0A6P7ZD87
names: Similarity
messages: Belongs to the SBNO family.

1415580:AASDH
gene id: 1415580:AASDH
uniprot id: A0A6P7WVQ6
uniprot id: A0A6P7X491
uniprot id: A0A6P7X9L8
uniprot id: A0A6P7XAW4
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

1415580:ZC3H15
gene id: 1415580:ZC3H15
uniprot id: A0A6P7YJ55
names: Similarity
messages: Belongs to the ZC3H15/TMA46 family.

1415580:LOC115479647
gene id: 1415580:LOC115479647
uniprot id: A0A6P7ZDU9
names: Similarity
messages: Belongs to the ARTD/PARP family.

1415580:TGFBR1
gene id: 1415580:TGFBR1
uniprot id: A0A6P7YDG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

1415580:RTF2
gene id: 1415580:RTF2
uniprot id: A0A6P7YYF5
names: Similarity
messages: Belongs to the rtf2 family.

1415580:TRMT1L
gene id: 1415580:TRMT1L
uniprot id: A0A6P7YH85
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: May play a role in motor coordination and exploratory behavior.

1415580:LOC115482103
gene id: 1415580:LOC115482103
uniprot id: A0A6P7ZV91
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:DDX27
gene id: 1415580:DDX27
uniprot id: A0A6P7YVK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family.
messages: Cytoplasm

1415580:SFT2D1
gene id: 1415580:SFT2D1
uniprot id: A0A6P7XU05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

1415580:BLOC1S5
gene id: 1415580:BLOC1S5
uniprot id: A0A6P7YBG9
uniprot id: A0A6P7YBH8
names: Function
names: Similarity
messages: Belongs to the BLOC1S5 family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO).

1415580:MMP16
gene id: 1415580:MMP16
uniprot id: A0A6P7Z9P4
names: Similarity
messages: Belongs to the peptidase M10A family.

1415580:SULF2
gene id: 1415580:SULF2
uniprot id: A0A6P7YQK8
uniprot id: A0A6P7YVH6
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1415580:ATP8
gene id: 1415580:ATP8
uniprot id: W5RHE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase protein 8 family.
messages: Membrane
messages: Mitochondrion membrane

1415580:PLBD2
gene id: 1415580:PLBD2
uniprot id: A0A6P7ZH69
names: Function
names: Similarity
messages: Belongs to the phospholipase B-like family.
messages: Putative phospholipase.

1415580:MYO1G
gene id: 1415580:MYO1G
uniprot id: A0A6P7XAF3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

1415580:MRI1
gene id: 1415580:MRI1
uniprot id: A0A6P7XAZ4
uniprot id: A0A6P7XHS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
messages: Cytoplasm
messages: Nucleus

1415580:SCAMP1
gene id: 1415580:SCAMP1
uniprot id: A0A6P7XFU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

1415580:LOC115478650
gene id: 1415580:LOC115478650
uniprot id: A0A6P7Z5V1
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

1415580:LOC115470394
gene id: 1415580:LOC115470394
uniprot id: A0A6P7Y2M2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
messages: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.

1415580:LOC115481329
gene id: 1415580:LOC115481329
uniprot id: A0A6P7ZEL1
uniprot id: A0A6P7ZPN2
names: Similarity
messages: Belongs to the intermediate filament family.

1415580:RAB27A
gene id: 1415580:RAB27A
uniprot id: A0A6P7X4G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

1415580:LOC115482152
gene id: 1415580:LOC115482152
uniprot id: A0A6P7ZVB9
names: Caution
names: Similarity
messages: Belongs to the FXYD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115475019
gene id: 1415580:LOC115475019
uniprot id: A0A6P7YGQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115458182
gene id: 1415580:LOC115458182
uniprot id: A0A6P7WU16
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:L1CAM
gene id: 1415580:L1CAM
uniprot id: A0A6P7XBS3
names: Similarity
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

1415580:LOC115463217
gene id: 1415580:LOC115463217
uniprot id: A0A6P7XGK2
names: Subcellular Location Annotation
messages: Peroxisome

1415580:TOMM20
gene id: 1415580:TOMM20
uniprot id: A0A6P7XL67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

1415580:LOC115461976
gene id: 1415580:LOC115461976
uniprot id: A0A6P7X3D0
names: Subcellular Location Annotation
messages: Membrane

1415580:SLC5A12
gene id: 1415580:SLC5A12
uniprot id: A0A6P7XU97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1415580:LOC115461536
gene id: 1415580:LOC115461536
uniprot id: A0A6P7X9K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Cytoplasm
messages: Nucleus
messages: Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.

1415580:PGLYRP1
gene id: 1415580:PGLYRP1
uniprot id: A0A6P7ZCS4
names: Function
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
messages: Innate immunity protein that plays several important functions in antimicrobial and antitumor defense systems.

1415580:UMOD
gene id: 1415580:UMOD
uniprot id: A0A6P7YKE2
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Basolateral cell membrane
messages: Cell membrane
messages: In the urine, may contribute to colloid osmotic pressure, retards passage of positively charged electrolytes, prevents urinary tract infection and inhibits formation of liquid containing supersaturated salts and subsequent formation of salt crystals.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: cilium membrane

1415580:LOC115457153
gene id: 1415580:LOC115457153
uniprot id: A0A6P7WGQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115480862
gene id: 1415580:LOC115480862
uniprot id: A0A6P7ZNQ6
names: Similarity
messages: Belongs to the 2-5A synthase family.

1415580:P2RX4
gene id: 1415580:P2RX4
uniprot id: A0A6P7ZCB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

1415580:MBOAT1
gene id: 1415580:MBOAT1
uniprot id: A0A6P7YIX8
uniprot id: A0A6P7YRQ5
uniprot id: A0A6P7YVS5
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115474980
gene id: 1415580:LOC115474980
uniprot id: A0A6P7YTJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

1415580:LOC115470194
gene id: 1415580:LOC115470194
uniprot id: A0A6P7Y1N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

1415580:LOC115457325
gene id: 1415580:LOC115457325
uniprot id: A0A6P7WXF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115461127
gene id: 1415580:LOC115461127
uniprot id: A0A6P7X286
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-II subfamily.

1415580:LOC115480577
gene id: 1415580:LOC115480577
uniprot id: A0A6P7ZLJ7
names: Similarity
messages: Belongs to the ATG8 family.

1415580:NSMCE2
gene id: 1415580:NSMCE2
uniprot id: A0A6P7ZIN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NSE2 family.
messages: Nucleus

1415580:PLCG2
gene id: 1415580:PLCG2
uniprot id: A0A6P7YBF1
names: Function
messages: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.

1415580:LOC115463675
gene id: 1415580:LOC115463675
uniprot id: A0A6P7XCI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 32 family.
messages: Golgi apparatus membrane

1415580:CBLB
gene id: 1415580:CBLB
uniprot id: A0A6P7YAD8
uniprot id: A0A6P7YB22
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

1415580:LOC115464589
gene id: 1415580:LOC115464589
uniprot id: A0A6P7XC48
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:SLC16A10
gene id: 1415580:SLC16A10
uniprot id: A0A6P7XX78
names: Subcellular Location Annotation
messages: Membrane

1415580:SLC12A3
gene id: 1415580:SLC12A3
uniprot id: A0A6P7Y3W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

1415580:STUM
gene id: 1415580:STUM
uniprot id: A0A6P7XAX4
uniprot id: A0A6P7XD68
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115481229
gene id: 1415580:LOC115481229
uniprot id: A0A6P7ZPG7
uniprot id: A0A6P7ZRS1
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

1415580:COQ8A
gene id: 1415580:COQ8A
uniprot id: A0A6P7XLQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.
messages: Membrane
messages: Mitochondrion

1415580:TCTE3
gene id: 1415580:TCTE3
uniprot id: A0A6P7X9J2
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

1415580:PGP
gene id: 1415580:PGP
uniprot id: A0A6P7YX24
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1415580:LOC115456993
gene id: 1415580:LOC115456993
uniprot id: A0A6P7WMI5
names: Similarity
messages: Belongs to the FMR1 family.

1415580:ERF
gene id: 1415580:ERF
uniprot id: A0A6P7YR95
uniprot id: A0A6P7YVY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

1415580:LOC115457202
gene id: 1415580:LOC115457202
uniprot id: A0A6P7WN57
names: Subcellular Location Annotation
messages: Membrane

1415580:TAF4B
gene id: 1415580:TAF4B
uniprot id: A0A6P7WU64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Nucleus

1415580:LOC115457446
gene id: 1415580:LOC115457446
uniprot id: A0A6P7WNT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

1415580:LOC115480222
gene id: 1415580:LOC115480222
uniprot id: A0A6P7ZG88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

1415580:LOC115464525
gene id: 1415580:LOC115464525
uniprot id: A0A6P7XE03
names: Subcellular Location Annotation
messages: Nucleus

1415580:GAL3ST2
gene id: 1415580:GAL3ST2
uniprot id: A0A6P7Z102
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

1415580:SSH3
gene id: 1415580:SSH3
uniprot id: A0A6P7WKW1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

1415580:PDCL2
gene id: 1415580:PDCL2
uniprot id: A0A6P7X3V9
names: Similarity
messages: Belongs to the phosducin family.

1415580:RPAP1
gene id: 1415580:RPAP1
uniprot id: A0A6P7YYF4
uniprot id: A0A6P7YZL3
uniprot id: A0A6P7Z2I0
names: Similarity
messages: Belongs to the RPAP1 family.

1415580:BGLAP
gene id: 1415580:BGLAP
uniprot id: A0A6P7WHM5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the osteocalcin/matrix Gla protein family.
messages: Binds strongly to apatite and calcium.
messages: Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium.
messages: Secreted

1415580:PCSK1
gene id: 1415580:PCSK1
uniprot id: A0A6P7X4D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin, insulin and AGRP.
messages: Vesicle
messages: secretory vesicle

1415580:LOC115467905
gene id: 1415580:LOC115467905
uniprot id: A0A6P7XIG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115478621
gene id: 1415580:LOC115478621
uniprot id: A0A6P7Z3K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

1415580:LOC115457251
gene id: 1415580:LOC115457251
uniprot id: A0A6P7WQ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:NADK
gene id: 1415580:NADK
uniprot id: A0A6P7X2C2
uniprot id: A0A6P7ZLJ1
uniprot id: A0A6P7ZVH0
names: Similarity
messages: Belongs to the NAD kinase family.

1415580:DNAAF2
gene id: 1415580:DNAAF2
uniprot id: A0A6P7Z6J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIH1 family. Kintoun subfamily.
messages: Cytoplasm
messages: Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment.

1415580:LOC115480505
gene id: 1415580:LOC115480505
uniprot id: A0A6P7ZF85
uniprot id: A0A6P7ZIS5
uniprot id: A0A6P7ZK26
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.

1415580:CSNK1A1
gene id: 1415580:CSNK1A1
uniprot id: A0A6P7YLH7
uniprot id: A0A6P7YTG6
uniprot id: A0A6P7YXR2
uniprot id: A0A6P7YYA8
names: Similarity
messages: Belongs to the protein kinase superfamily.

1415580:LOC115456478
gene id: 1415580:LOC115456478
uniprot id: A0A6P7WMD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

1415580:AGO4
gene id: 1415580:AGO4
uniprot id: A0A6P7Z1I7
uniprot id: A0A6P7Z9H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the argonaute family.
messages: Belongs to the argonaute family. Ago subfamily.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.

1415580:EP400
gene id: 1415580:EP400
uniprot id: A0A6P7Z8I3
uniprot id: A0A6P7ZD50
uniprot id: A0A6P7ZHE8
names: Subcellular Location Annotation
messages: Nucleus

1415580:ALDH1L2
gene id: 1415580:ALDH1L2
uniprot id: A0A6P7Z4F3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
messages: In the N-terminal section; belongs to the GART family.

1415580:NDRG4
gene id: 1415580:NDRG4
uniprot id: A0A6P7Y2S7
uniprot id: A0A6P7Y9F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDRG family.
messages: cytosol

1415580:OSTC
gene id: 1415580:OSTC
uniprot id: A0A6P7XDW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OSTC family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Specific component of the STT3A-containing form of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

1415580:IDUA
gene id: 1415580:IDUA
uniprot id: A0A6P7XI42
uniprot id: A0A6P7XJ72
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

1415580:LOC115471025
gene id: 1415580:LOC115471025
uniprot id: A0A6P7YCK1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:NPTXR
gene id: 1415580:NPTXR
uniprot id: A0A6P7YH25
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:PPIL2
gene id: 1415580:PPIL2
uniprot id: A0A6P7ZDU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.
messages: Nucleus

1415580:SLC30A2
gene id: 1415580:SLC30A2
uniprot id: A0A6P7ZCT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

1415580:RAB9A
gene id: 1415580:RAB9A
uniprot id: A0A6P7XQ20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: phagosome membrane

1415580:UBL4A
gene id: 1415580:UBL4A
uniprot id: A0A6P7XHF2
names: Subcellular Location Annotation
messages: cytosol

1415580:LHX9
gene id: 1415580:LHX9
uniprot id: A0A6P7YAT7
uniprot id: A0A6P7YGD3
uniprot id: A0A6P7YGY0
names: Subcellular Location Annotation
messages: Nucleus

1415580:RPP30
gene id: 1415580:RPP30
uniprot id: A0A6P7Y6R8
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

1415580:MED6
gene id: 1415580:MED6
uniprot id: A0A6P7Z226
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 6 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1415580:AGA
gene id: 1415580:AGA
uniprot id: A0A6P7X7U9
uniprot id: A0A6P7XE97
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

1415580:NDFIP2
gene id: 1415580:NDFIP2
uniprot id: A0A6P7Y0Z0
names: Subcellular Location Annotation
messages: Membrane

1415580:ITGA5
gene id: 1415580:ITGA5
uniprot id: A0A6P7XNQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

1415580:SLC23A2
gene id: 1415580:SLC23A2
uniprot id: A0A6P7Y4M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1415580:RORC
gene id: 1415580:RORC
uniprot id: A0A6P7WJZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

1415580:CNTNAP5
gene id: 1415580:CNTNAP5
uniprot id: A0A6P7YCM5
uniprot id: A0A6P7YJU7
uniprot id: A0A6P7YK80
uniprot id: A0A6P7YQ47
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a role in the correct development and proper functioning of the peripheral and central nervous system and be involved in cell adhesion and intercellular communication.
messages: Membrane

1415580:LOC115458231
gene id: 1415580:LOC115458231
uniprot id: A0A6P7WRZ3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:POLM
gene id: 1415580:POLM
uniprot id: A0A6P7XQ83
uniprot id: A0A6P7XX35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ).
messages: Nucleus

1415580:RDH5
gene id: 1415580:RDH5
uniprot id: A0A6P7XQG8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1415580:IFT57
gene id: 1415580:IFT57
uniprot id: A0A6P7XX80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFT57 family.
messages: cilium basal body

1415580:LOC115457418
gene id: 1415580:LOC115457418
uniprot id: A0A6P7WNQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:RHBDL3
gene id: 1415580:RHBDL3
uniprot id: A0A6P7YHH5
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115464887
gene id: 1415580:LOC115464887
uniprot id: A0A6P7XKF3
names: Similarity
messages: Belongs to the tumor necrosis factor family.

1415580:TSR3
gene id: 1415580:TSR3
uniprot id: A0A6P7YHU5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1248 (Psi1248) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:GUSB
gene id: 1415580:GUSB
uniprot id: A0A6P7ZFW5
uniprot id: A0A6P7ZVU1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Homotetramer.
messages: Inhibited by L-aspartic acid.
messages: Lysosome
messages: Plays an important role in the degradation of dermatan and keratan sulfates.

1415580:DHPS
gene id: 1415580:DHPS
uniprot id: A0A6P7XLC6
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

1415580:WDR82
gene id: 1415580:WDR82
uniprot id: A0A6P7YMX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SWD2 family.
messages: Nucleus

1415580:SLC35A3
gene id: 1415580:SLC35A3
uniprot id: A0A6P7Y3P9
uniprot id: A0A6P7YAR4
uniprot id: A0A6P7YGW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

1415580:SLC25A13
gene id: 1415580:SLC25A13
uniprot id: A0A6P7XMT1
uniprot id: A0A6P7XVW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1415580:CORO1C
gene id: 1415580:CORO1C
uniprot id: A0A6P7Z466
uniprot id: A0A6P7ZES2
names: Similarity
messages: Belongs to the WD repeat coronin family.

1415580:MSRA
gene id: 1415580:MSRA
uniprot id: A0A6P7XGC8
uniprot id: A0A6P7XN69
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.

1415580:LOC115481412
gene id: 1415580:LOC115481412
uniprot id: A0A6P7ZQ99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

1415580:DECR2
gene id: 1415580:DECR2
uniprot id: A0A6P7YW78
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily.
messages: Monomer, dimer and oligomer.

1415580:KIF17
gene id: 1415580:KIF17
uniprot id: A0A6P7WUQ4
uniprot id: A0A6P7WVR2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

1415580:LOC115457352
gene id: 1415580:LOC115457352
uniprot id: A0A6P7WWK4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:CCNJ
gene id: 1415580:CCNJ
uniprot id: A0A6P7XZ81
names: Similarity
messages: Belongs to the cyclin family.

1415580:LOC115463051
gene id: 1415580:LOC115463051
uniprot id: A0A6P7X0N0
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1415580:IREB2
gene id: 1415580:IREB2
uniprot id: A0A6P7WUA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Cytoplasm
messages: RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.

1415580:SLC16A9
gene id: 1415580:SLC16A9
uniprot id: A0A6P7XU32
uniprot id: A0A6P7Y2B3
names: Subcellular Location Annotation
messages: Membrane

1415580:CDH8
gene id: 1415580:CDH8
uniprot id: A0A6P7Y5U7
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

1415580:LOC115475370
gene id: 1415580:LOC115475370
uniprot id: A0A6P7YUF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Cell membrane
messages: Membrane

1415580:SUPT20H
gene id: 1415580:SUPT20H
uniprot id: A0A6P7XLI7
uniprot id: A0A6P7XLJ3
uniprot id: A0A6P7XTC8
uniprot id: A0A6P7XUS6
uniprot id: A0A6P7XUT2
uniprot id: A0A6P7XZU7
uniprot id: A0A6P7Y0E6
uniprot id: A0A6P7Y0E9
names: Similarity
messages: Belongs to the SPT20 family.

1415580:PTPRB
gene id: 1415580:PTPRB
uniprot id: A0A6P7YYF8
uniprot id: A0A6P7Z2I5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily.

1415580:CUL2
gene id: 1415580:CUL2
uniprot id: A0A6P7XQV2
names: Similarity
messages: Belongs to the cullin family.

1415580:ENDOU
gene id: 1415580:ENDOU
uniprot id: A0A6P7XU25
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

1415580:CRBN
gene id: 1415580:CRBN
uniprot id: A0A6P7YFP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRBN family.
messages: Nucleus

1415580:LOC115475121
gene id: 1415580:LOC115475121
uniprot id: A0A6P7YNX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DZIP C2H2-type zinc-finger protein family.
messages: centriole
messages: cilium basal body

1415580:LOC115479913
gene id: 1415580:LOC115479913
uniprot id: A0A6P7Z965
names: Similarity
messages: Belongs to the 2-5A synthase family.

1415580:ACSL5
gene id: 1415580:ACSL5
uniprot id: A0A6P7XT38
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

1415580:LOC115465865
gene id: 1415580:LOC115465865
uniprot id: A0A6P7XPB4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1415580:KAT8
gene id: 1415580:KAT8
uniprot id: A0A6P7YKG9
uniprot id: A0A6P7YPY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

1415580:MAN1C1
gene id: 1415580:MAN1C1
uniprot id: A0A6P7ZDU5
uniprot id: A0A6P7ZGF1
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

1415580:LOC115468788
gene id: 1415580:LOC115468788
uniprot id: A0A6P7Y0R7
uniprot id: A0A6P7Y1D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
messages: Peroxisome

1415580:NUDT6
gene id: 1415580:NUDT6
uniprot id: A0A6P7X414
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Cytoplasm
messages: May contribute to the regulation of cell proliferation.
messages: Mitochondrion
messages: Monomer and homodimer.
messages: Nucleus

1415580:LOC115481160
gene id: 1415580:LOC115481160
uniprot id: A0A6P7ZNQ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1415580:UGT3A2
gene id: 1415580:UGT3A2
uniprot id: A0A6P7X6H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

1415580:RP2
gene id: 1415580:RP2
uniprot id: A0A6P7Y2U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.
messages: Belongs to the TBCC family.
messages: Cell membrane
messages: Membrane

1415580:LOC115458032
gene id: 1415580:LOC115458032
uniprot id: A0A6P7X0I7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane

1415580:LOC115479938
gene id: 1415580:LOC115479938
uniprot id: A0A6P7Z489
names: Similarity
messages: Belongs to the cytochrome P450 family.

1415580:PLEKHA8
gene id: 1415580:PLEKHA8
uniprot id: A0A6P7Y0Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLTP family.
messages: Membrane
messages: trans-Golgi network membrane

1415580:LOC115457205
gene id: 1415580:LOC115457205
uniprot id: A0A6P7WW56
names: Subcellular Location Annotation
messages: Membrane

1415580:RHOT2
gene id: 1415580:RHOT2
uniprot id: A0A6P7YSW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking.
messages: Mitochondrion outer membrane

1415580:TFDP2
gene id: 1415580:TFDP2
uniprot id: A0A6P7Z3S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

1415580:LOC115457051
gene id: 1415580:LOC115457051
uniprot id: A0A6P7WVR3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:FUT4
gene id: 1415580:FUT4
uniprot id: A0A6P7XI99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

1415580:LOC115472533
gene id: 1415580:LOC115472533
uniprot id: A0A6P7Y586
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.

1415580:LOC115461191
gene id: 1415580:LOC115461191
uniprot id: A0A6P7X2P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:ORC3
gene id: 1415580:ORC3
uniprot id: A0A6P7X7F7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC3 family.
messages: Component of ORC, a complex composed of at least 6 subunits: ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. ORC is regulated in a cell-cycle dependent manner. It is sequentially assembled at the exit from anaphase of mitosis and disassembled as cells enter S phase.
messages: Nucleus

1415580:LOC115464451
gene id: 1415580:LOC115464451
uniprot id: A0A6P7XBL9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:CD34
gene id: 1415580:CD34
uniprot id: A0A6P7ZQH5
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115479937
gene id: 1415580:LOC115479937
uniprot id: A0A6P7ZDB8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

1415580:PROK2
gene id: 1415580:PROK2
uniprot id: A0A6P7Y522
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AVIT (prokineticin) family.
messages: Secreted

1415580:LOC115475023
gene id: 1415580:LOC115475023
uniprot id: A0A6P7YGQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115466250
gene id: 1415580:LOC115466250
uniprot id: A0A6P7XJ74
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1415580:TOP2A
gene id: 1415580:TOP2A
uniprot id: A0A6P7ZG94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Homodimer.
messages: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand.
messages: nucleolus
messages: nucleoplasm

1415580:RBM15B
gene id: 1415580:RBM15B
uniprot id: A0A6P7YC37
names: Similarity
messages: Belongs to the RRM Spen family.

1415580:LOC115481812
gene id: 1415580:LOC115481812
uniprot id: A0A6P7ZGM9
uniprot id: A0A6P7ZUH4
names: Similarity
messages: Belongs to the NXPE family.

1415580:TNR
gene id: 1415580:TNR
uniprot id: A0A6P7Y500
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: extracellular matrix

1415580:SRD5A1
gene id: 1415580:SRD5A1
uniprot id: A0A6P7YKD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane

1415580:BCL9L
gene id: 1415580:BCL9L
uniprot id: A0A6P7ZBL2
uniprot id: A0A6P7ZNW8
uniprot id: A0A6P7ZSD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCL9 family.
messages: Nucleus

1415580:DUSP8
gene id: 1415580:DUSP8
uniprot id: A0A6P7Y236
uniprot id: A0A6P7Y2M8
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

1415580:NDUFAF4
gene id: 1415580:NDUFAF4
uniprot id: A0A6P7X7F1
names: Similarity
names: Subunit
messages: Belongs to the NDUFAF4 family.
messages: Binds calmodulin. Interacts with NDUFAF3.

1415580:AK4
gene id: 1415580:AK4
uniprot id: A0A6P7YIA3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP/ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP/ATP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity.
messages: Mitochondrion matrix
messages: Monomer.

1415580:LOC115458246
gene id: 1415580:LOC115458246
uniprot id: A0A6P7X0A3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:CNPY1
gene id: 1415580:CNPY1
uniprot id: A0A6P7XUK4
names: Similarity
messages: Belongs to the canopy family.

1415580:IQCD
gene id: 1415580:IQCD
uniprot id: A0A6P7ZFN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC10 family.
messages: Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.
messages: flagellum axoneme

1415580:FADS2
gene id: 1415580:FADS2
uniprot id: A0A6P7XWY4
uniprot id: A0A6P7Y2H3
names: Similarity
messages: Belongs to the fatty acid desaturase type 1 family.

1415580:B4GALT4
gene id: 1415580:B4GALT4
uniprot id: A0A6P7Y4G9
uniprot id: A0A6P7YAC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

1415580:LOC115466191
gene id: 1415580:LOC115466191
uniprot id: A0A6P7XC45
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse
messages: axon
messages: dendrite

1415580:RPS23
gene id: 1415580:RPS23
uniprot id: A0A6P7X2U8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Component of the 40S small ribosomal subunit.
messages: Rough endoplasmic reticulum

1415580:GRK6
gene id: 1415580:GRK6
uniprot id: A0A6P7YVQ7
uniprot id: A0A6P7Z002
uniprot id: A0A6P7Z0Q2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

1415580:ZC3H12B
gene id: 1415580:ZC3H12B
uniprot id: A0A6P7YSD3
names: Similarity
messages: Belongs to the ZC3H12 family.

1415580:FAM189A2
gene id: 1415580:FAM189A2
uniprot id: A0A6P7XHG5
names: Similarity
messages: Belongs to the ENTREP family.

1415580:VPS52
gene id: 1415580:VPS52
uniprot id: A0A6P7XBY2
names: Similarity
messages: Belongs to the VPS52 family.

1415580:SMS
gene id: 1415580:SMS
uniprot id: A0A6P7XYY0
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

1415580:RPS5
gene id: 1415580:RPS5
uniprot id: A0A6P7XRV9
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

1415580:LOC115472229
gene id: 1415580:LOC115472229
uniprot id: A0A6P7YGY3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:PTGES
gene id: 1415580:PTGES
uniprot id: A0A6P7YL27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Membrane

1415580:ATP6V1E1
gene id: 1415580:ATP6V1E1
uniprot id: A0A6P7Z493
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

1415580:NPM2
gene id: 1415580:NPM2
uniprot id: A0A6P7XY16
uniprot id: A0A6P7Y451
uniprot id: A0A6P7Y515
names: Similarity
messages: Belongs to the nucleoplasmin family.

1415580:VPS33B
gene id: 1415580:VPS33B
uniprot id: A0A6P7WWK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

1415580:ZC3HC1
gene id: 1415580:ZC3HC1
uniprot id: A0A6P7ZB00
names: Subcellular Location Annotation
messages: Nucleus

1415580:PALMD
gene id: 1415580:PALMD
uniprot id: A0A6P7YE91
uniprot id: A0A6P7YEY8
names: Similarity
messages: Belongs to the paralemmin family.

1415580:PIK3C3
gene id: 1415580:PIK3C3
uniprot id: A0A6P7X607
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
messages: Midbody

1415580:ANTKMT
gene id: 1415580:ANTKMT
uniprot id: A0A6P7YS56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANT/ATPSC lysine N-methyltransferase family.
messages: Mitochondrion membrane

1415580:PDZK1IP1
gene id: 1415580:PDZK1IP1
uniprot id: A0A6P7Y771
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115474167
gene id: 1415580:LOC115474167
uniprot id: A0A6P7YD05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

1415580:ABI2
gene id: 1415580:ABI2
uniprot id: A0A6P7YC87
uniprot id: A0A6P7YJS6
uniprot id: A0A6P7YPE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABI family.
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

1415580:NFIC
gene id: 1415580:NFIC
uniprot id: A0A6P7Z1B8
uniprot id: A0A6P7Z6S6
uniprot id: A0A6P7ZBV7
uniprot id: A0A6P7ZCQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

1415580:ARHGEF9
gene id: 1415580:ARHGEF9
uniprot id: A0A6P7YMX8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Acts as guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters.
messages: Cytoplasm
messages: Interacts with GPHN.
messages: Postsynaptic density

1415580:LOC115479873
gene id: 1415580:LOC115479873
uniprot id: A0A6P7Z3Y5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

1415580:AKT1
gene id: 1415580:AKT1
uniprot id: A0A6P7Z352
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

1415580:GDPD5
gene id: 1415580:GDPD5
uniprot id: A0A6P7XKB8
uniprot id: A0A6P7XTR2
uniprot id: A0A6P7XYT0
uniprot id: A0A6P7XZH1
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

1415580:PRPSAP2
gene id: 1415580:PRPSAP2
uniprot id: A0A6P7YXB0
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1415580:PSME1
gene id: 1415580:PSME1
uniprot id: A0A6P7WS16
names: Similarity
messages: Belongs to the PA28 family.

1415580:LOC115461461
gene id: 1415580:LOC115461461
uniprot id: A0A6P7WVD5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:LOC115460505
gene id: 1415580:LOC115460505
uniprot id: A0A6P7X6C2
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

1415580:FUS
gene id: 1415580:FUS
uniprot id: A0A6P7YN90
uniprot id: A0A6P7YNN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TET family.
messages: Nucleus

1415580:RBM5
gene id: 1415580:RBM5
uniprot id: A0A6P7Y890
uniprot id: A0A6P7YEF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RBM5/RBM10 family.
messages: Nucleus

1415580:NT5C3B
gene id: 1415580:NT5C3B
uniprot id: A0A6P7ZCT3
uniprot id: A0A6P7ZS21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

1415580:ISCA2
gene id: 1415580:ISCA2
uniprot id: A0A6P7YYW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HesB/IscA family.
messages: Mitochondrion

1415580:ZNF830
gene id: 1415580:ZNF830
uniprot id: A0A6P7YCT4
uniprot id: A0A6P7YCV0
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus speckle

1415580:ADORA2B
gene id: 1415580:ADORA2B
uniprot id: A0A6P7ZLM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

1415580:LOC115475884
gene id: 1415580:LOC115475884
uniprot id: A0A6P7YS61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

1415580:CORO2A
gene id: 1415580:CORO2A
uniprot id: A0A6P7XIV0
names: Similarity
messages: Belongs to the WD repeat coronin family.

1415580:XCR1
gene id: 1415580:XCR1
uniprot id: A0A6P7X091
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:SLC30A6
gene id: 1415580:SLC30A6
uniprot id: A0A6P7XTF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

1415580:MARCHF11
gene id: 1415580:MARCHF11
uniprot id: A0A6P7X069
names: Subcellular Location Annotation
messages: Membrane

1415580:MVB12B
gene id: 1415580:MVB12B
uniprot id: A0A6P7YE62
uniprot id: A0A6P7YEG0
uniprot id: A0A6P7YK31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MVB12 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

1415580:CNNM3
gene id: 1415580:CNNM3
uniprot id: A0A6P7XY77
uniprot id: A0A6P7Y426
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Membrane

1415580:KIF15
gene id: 1415580:KIF15
uniprot id: A0A6P7YPV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: spindle

1415580:LOC115465750
gene id: 1415580:LOC115465750
uniprot id: A0A6P7XNU7
names: Similarity
names: Subunit
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Ribosomal protein S27a is part of the 40S ribosomal subunit.

1415580:GPHB5
gene id: 1415580:GPHB5
uniprot id: A0A6P7Z3Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

1415580:LOC115457242
gene id: 1415580:LOC115457242
uniprot id: A0A6P7WW92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

1415580:LOC115471006
gene id: 1415580:LOC115471006
uniprot id: A0A6P7YCI0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:LOC115471310
gene id: 1415580:LOC115471310
uniprot id: A0A6P7Y7B9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

1415580:IBSP
gene id: 1415580:IBSP
uniprot id: A0A6P7X7F8
names: Function
names: Subcellular Location Annotation
messages: Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment.
messages: Secreted

1415580:GLRA1
gene id: 1415580:GLRA1
uniprot id: A0A6P7YWD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

1415580:RFTN2
gene id: 1415580:RFTN2
uniprot id: A0A6P7YDB1
uniprot id: A0A6P7YKG2
uniprot id: A0A6P7YQR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the raftlin family.
messages: Cell membrane
messages: Membrane

1415580:LOC115475119
gene id: 1415580:LOC115475119
uniprot id: A0A6P7YTW8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:PAPPA2
gene id: 1415580:PAPPA2
uniprot id: A0A6P7YCY4
names: Caution
names: Similarity
messages: Belongs to the peptidase M43B family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LRRC8B
gene id: 1415580:LRRC8B
uniprot id: A0A6P7Y386
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

1415580:STRN4
gene id: 1415580:STRN4
uniprot id: A0A6P7Z7B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

1415580:PSKH1
gene id: 1415580:PSKH1
uniprot id: A0A6P7Y2Z9
names: Similarity
messages: Belongs to the protein kinase superfamily.

1415580:TMEM182
gene id: 1415580:TMEM182
uniprot id: A0A6P7XSB4
uniprot id: A0A6P7XY83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM182 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115482428
gene id: 1415580:LOC115482428
uniprot id: A0A6P7ZXV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

1415580:TAF12
gene id: 1415580:TAF12
uniprot id: A0A6P7Z5D6
uniprot id: A0A6P7ZGH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF12 family.
messages: Nucleus

1415580:ARTN
gene id: 1415580:ARTN
uniprot id: A0A6P7Y5P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

1415580:LOC115468863
gene id: 1415580:LOC115468863
uniprot id: A0A6P7XWB7
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

1415580:UTP3
gene id: 1415580:UTP3
uniprot id: A0A6P7WEG5
uniprot id: A0A6P7WTI6
names: Similarity
messages: Belongs to the SAS10 family.

1415580:GPR37
gene id: 1415580:GPR37
uniprot id: A0A6P7Z5S9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:CCNE1
gene id: 1415580:CCNE1
uniprot id: A0A6P7XZU9
names: Similarity
messages: Belongs to the cyclin family. Cyclin E subfamily.

1415580:LOC115480456
gene id: 1415580:LOC115480456
uniprot id: A0A6P7ZHJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ran family.
messages: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
messages: Nucleus

1415580:LOC115462533
gene id: 1415580:LOC115462533
uniprot id: A0A6P7WYQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115479235
gene id: 1415580:LOC115479235
uniprot id: A0A6P7Z8K4
uniprot id: A0A6P7ZB96
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:FAM8A1
gene id: 1415580:FAM8A1
uniprot id: A0A6P7YQE2
names: Subcellular Location Annotation
messages: Membrane

1415580:ND5
gene id: 1415580:ND5
uniprot id: W5RHG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

1415580:LOC115470535
gene id: 1415580:LOC115470535
uniprot id: A0A6P7Y9Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANT/ATPSC lysine N-methyltransferase family.
messages: Mitochondrion membrane

1415580:HSD17B1
gene id: 1415580:HSD17B1
uniprot id: A0A6P7ZCW6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1415580:EAF2
gene id: 1415580:EAF2
uniprot id: A0A6P7YMD3
names: Similarity
messages: Belongs to the EAF family.

1415580:NUS1
gene id: 1415580:NUS1
uniprot id: A0A6P7XFV2
names: Similarity
messages: Belongs to the UPP synthase family.

1415580:LOC115462853
gene id: 1415580:LOC115462853
uniprot id: A0A6P7WZQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS1 family.
messages: spindle

1415580:ACO2
gene id: 1415580:ACO2
uniprot id: A0A6P7YN84
uniprot id: A0A6P7YSL7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
messages: Mitochondrion

1415580:VIP
gene id: 1415580:VIP
uniprot id: A0A6P7XLZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted
messages: VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder.

1415580:TLR4
gene id: 1415580:TLR4
uniprot id: A0A6P7YCB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

1415580:USP5
gene id: 1415580:USP5
uniprot id: A0A6P7WG26
uniprot id: A0A6P7WP73
names: Similarity
messages: Belongs to the peptidase C19 family.

1415580:STK3
gene id: 1415580:STK3
uniprot id: A0A6P7Z0Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Nucleus

1415580:LOC115461985
gene id: 1415580:LOC115461985
uniprot id: A0A6P7XCK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:GLT8D2
gene id: 1415580:GLT8D2
uniprot id: A0A6P7Z4V8
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115469403
gene id: 1415580:LOC115469403
uniprot id: A0A6P7XY44
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115457034
gene id: 1415580:LOC115457034
uniprot id: A0A6P7WGF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115475986
gene id: 1415580:LOC115475986
uniprot id: A0A6P7YXC6
names: Subcellular Location Annotation
messages: Membrane

1415580:NTN3
gene id: 1415580:NTN3
uniprot id: A0A6P7YPJ0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115473303
gene id: 1415580:LOC115473303
uniprot id: A0A6P7Y941
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

1415580:BAZ2A
gene id: 1415580:BAZ2A
uniprot id: A0A6P7XPE4
names: Similarity
messages: Belongs to the WAL family.

1415580:LOC115462399
gene id: 1415580:LOC115462399
uniprot id: A0A6P7X2N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.
messages: Cytoplasm
messages: Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.

1415580:NT5DC2
gene id: 1415580:NT5DC2
uniprot id: A0A6P7X314
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

1415580:NXPE3
gene id: 1415580:NXPE3
uniprot id: A0A6P7YAD0
names: Similarity
messages: Belongs to the NXPE family.

1415580:SUV39H1
gene id: 1415580:SUV39H1
uniprot id: A0A6P7X755
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
messages: Nucleus
messages: centromere

1415580:LOC115456963
gene id: 1415580:LOC115456963
uniprot id: A0A6P7WG84
uniprot id: A0A6P7WPB6
uniprot id: A0A6P7WPC2
uniprot id: A0A6P7WVB4
uniprot id: A0A6P7WWD3
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

1415580:LOC115466558
gene id: 1415580:LOC115466558
uniprot id: A0A6P7XKM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP31 family.
messages: Cajal body

1415580:CHAT
gene id: 1415580:CHAT
uniprot id: A0A6P7Y792
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

1415580:LIX1
gene id: 1415580:LIX1
uniprot id: A0A6P7X7J3
names: Similarity
messages: Belongs to the LIX1 family.

1415580:LOC115482128
gene id: 1415580:LOC115482128
uniprot id: A0A6P7ZIZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

1415580:PFN3
gene id: 1415580:PFN3
uniprot id: A0A6P7YZD0
names: Similarity
messages: Belongs to the profilin family.

1415580:KCNAB2
gene id: 1415580:KCNAB2
uniprot id: A0A6P7ZF67
uniprot id: A0A6P7ZF72
uniprot id: A0A6P7ZL26
uniprot id: A0A6P7ZVB0
uniprot id: A0A6P7ZXG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: axon
messages: cytoskeleton
messages: synaptosome

1415580:LOC115462647
gene id: 1415580:LOC115462647
uniprot id: A0A6P7X5C7
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

1415580:SNRPC
gene id: 1415580:SNRPC
uniprot id: A0A6P7ZUR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the U1 small nuclear ribonucleoprotein C family.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. snrpc/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates E complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Nucleus
messages: U1 snRNP is composed of the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C. SNRPC/U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA.

1415580:KIF26A
gene id: 1415580:KIF26A
uniprot id: A0A6P7YSR0
uniprot id: A0A6P7Z0C4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

1415580:PNCK
gene id: 1415580:PNCK
uniprot id: A0A6P7XBQ0
names: Similarity
messages: Belongs to the protein kinase superfamily.

1415580:RAD51
gene id: 1415580:RAD51
uniprot id: A0A6P7Z2U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Nucleus
messages: Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR). Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Recruited to resolve stalled replication forks during replication stress. Also involved in interstrand cross-link repair.

1415580:LOC115466338
gene id: 1415580:LOC115466338
uniprot id: A0A6P7XCT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

1415580:CRB1
gene id: 1415580:CRB1
uniprot id: A0A6P7Y505
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:TNS2
gene id: 1415580:TNS2
uniprot id: A0A6P7XLI5
uniprot id: A0A6P7XTR9
uniprot id: A0A6P7XUB2
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

1415580:LOC115476730
gene id: 1415580:LOC115476730
uniprot id: A0A6P7YPD8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the noggin family.
messages: Homodimer.
messages: Secreted

1415580:LOC115457710
gene id: 1415580:LOC115457710
uniprot id: A0A6P7WRW3
names: Similarity
messages: Belongs to the ARS2 family.

1415580:LOC115481516
gene id: 1415580:LOC115481516
uniprot id: A0A6P7ZB48
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

1415580:LOC115478675
gene id: 1415580:LOC115478675
uniprot id: A0A6P7Z8M0
names: Subcellular Location Annotation
messages: Membrane

1415580:SNRPD3
gene id: 1415580:SNRPD3
uniprot id: A0A6P7Z9I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

1415580:FZD4
gene id: 1415580:FZD4
uniprot id: A0A6P7XSI2
uniprot id: A0A6P7XZ28
uniprot id: A0A6P7XZQ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:C2H20orf27
gene id: 1415580:C2H20orf27
uniprot id: A0A6P7X0E1
names: Similarity
messages: Belongs to the UPF0687 family.

1415580:BAZ1B
gene id: 1415580:BAZ1B
uniprot id: A0A6P7WUG4
names: Subcellular Location Annotation
messages: Nucleus

1415580:PUS7
gene id: 1415580:PUS7
uniprot id: A0A6P7Z5J0
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

1415580:LOC115468301
gene id: 1415580:LOC115468301
uniprot id: A0A6P7XYK4
uniprot id: A0A6P7XZ77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:SLC16A14
gene id: 1415580:SLC16A14
uniprot id: A0A6P7ZBS5
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115482434
gene id: 1415580:LOC115482434
uniprot id: A0A6P7ZXW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

1415580:LOC115462492
gene id: 1415580:LOC115462492
uniprot id: A0A6P7X4W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEAP2 family.
messages: Has an antimicrobial activity.
messages: Secreted

1415580:VAMP5
gene id: 1415580:VAMP5
uniprot id: A0A6P7XY96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

1415580:LOC115472251
gene id: 1415580:LOC115472251
uniprot id: A0A6P7YHE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Mitochondrion intermembrane space

1415580:PDE5A
gene id: 1415580:PDE5A
uniprot id: A0A6P7X2P1
uniprot id: A0A6P7X593
uniprot id: A0A6P7XAP8
uniprot id: A0A6P7XBX7
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

1415580:LOC115475141
gene id: 1415580:LOC115475141
uniprot id: A0A6P7YU07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

1415580:CHST10
gene id: 1415580:CHST10
uniprot id: A0A6P7Y2Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

1415580:SDR42E1
gene id: 1415580:SDR42E1
uniprot id: A0A6P7Y5W8
uniprot id: A0A6P7Y5Z5
names: Similarity
messages: Belongs to the 3-beta-HSD family.

1415580:EGR2
gene id: 1415580:EGR2
uniprot id: A0A6P7Y883
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus

1415580:SLC6A1
gene id: 1415580:SLC6A1
uniprot id: A0A6P7Y2D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1415580:MEOX2
gene id: 1415580:MEOX2
uniprot id: A0A6P7WRK1
names: Subcellular Location Annotation
messages: Nucleus

1415580:PLA2G4D
gene id: 1415580:PLA2G4D
uniprot id: A0A6P7YT12
uniprot id: A0A6P7Z0L3
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

1415580:LOC115461247
gene id: 1415580:LOC115461247
uniprot id: A0A6P7X2Y3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:CUL1
gene id: 1415580:CUL1
uniprot id: A0A6P7Y9P7
names: Similarity
messages: Belongs to the cullin family.

1415580:LYAR
gene id: 1415580:LYAR
uniprot id: A0A6P7WYY5
names: Subcellular Location Annotation
messages: Cytoplasm

1415580:LOC115457077
gene id: 1415580:LOC115457077
uniprot id: A0A6P7WMQ7
names: Subcellular Location Annotation
messages: Membrane

1415580:CCNE2
gene id: 1415580:CCNE2
uniprot id: A0A6P7ZAH3
names: Similarity
messages: Belongs to the cyclin family. Cyclin E subfamily.

1415580:BORA
gene id: 1415580:BORA
uniprot id: A0A6P7XM67
uniprot id: A0A6P7XTV6
uniprot id: A0A6P7Y092
uniprot id: A0A6P7Y0U1
names: Similarity
messages: Belongs to the BORA family.

1415580:HS3ST6
gene id: 1415580:HS3ST6
uniprot id: A0A6P7YX07
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

1415580:LOC115467811
gene id: 1415580:LOC115467811
uniprot id: A0A6P7XI39
uniprot id: A0A6P7XRN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1415580:LOC115461954
gene id: 1415580:LOC115461954
uniprot id: A0A6P7XBC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115477444
gene id: 1415580:LOC115477444
uniprot id: A0A6P7YZ12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL27 family.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum

1415580:LOC115464799
gene id: 1415580:LOC115464799
uniprot id: A0A6P7XK65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates.
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
messages: Cytoplasm

1415580:LOC115457170
gene id: 1415580:LOC115457170
uniprot id: A0A6P7WX06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:JAKMIP1
gene id: 1415580:JAKMIP1
uniprot id: A0A6P7X3K3
names: Similarity
messages: Belongs to the JAKMIP family.

1415580:LOC115464686
gene id: 1415580:LOC115464686
uniprot id: A0A6P7XJV7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:RPS13
gene id: 1415580:RPS13
uniprot id: A0A6P7XS87
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

1415580:ZFP36L1
gene id: 1415580:ZFP36L1
uniprot id: A0A6P7Z3H7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

1415580:USP1
gene id: 1415580:USP1
uniprot id: A0A6P7Y903
uniprot id: A0A6P7YEB9
names: Similarity
messages: Belongs to the peptidase C19 family.

1415580:LOC115475032
gene id: 1415580:LOC115475032
uniprot id: A0A6P7YPH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:FLI1
gene id: 1415580:FLI1
uniprot id: A0A6P7ZE92
uniprot id: A0A6P7ZJB4
uniprot id: A0A6P7ZUP0
uniprot id: A0A6P7ZVF6
uniprot id: A0A6P7ZWA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

1415580:LOC115479787
gene id: 1415580:LOC115479787
uniprot id: A0A6P7X5J9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1415580:LOC115456755
gene id: 1415580:LOC115456755
uniprot id: A0A6P7WLI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GST superfamily. Pi family.
messages: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
messages: Cytoplasm
messages: Homodimer.
messages: Mitochondrion
messages: Nucleus

1415580:DPYSL2
gene id: 1415580:DPYSL2
uniprot id: A0A6P7XQN3
uniprot id: A0A6P7XYP2
uniprot id: A0A6P7Y4L6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

1415580:SLC27A4
gene id: 1415580:SLC27A4
uniprot id: A0A6P7YL26
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

1415580:LOC115468267
gene id: 1415580:LOC115468267
uniprot id: A0A6P7XJR0
uniprot id: A0A6P7XRJ0
uniprot id: A0A6P7XRK1
uniprot id: A0A6P7XYC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:GPR180
gene id: 1415580:GPR180
uniprot id: A0A6P7Y316
names: Subcellular Location Annotation
messages: Membrane

1415580:MYO1B
gene id: 1415580:MYO1B
uniprot id: A0A6P7YBG1
uniprot id: A0A6P7YBG4
uniprot id: A0A6P7YIK2
uniprot id: A0A6P7YIV4
uniprot id: A0A6P7YIV8
uniprot id: A0A6P7YNP3
uniprot id: A0A6P7YNP7
uniprot id: A0A6P7YP45
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

1415580:PTK2
gene id: 1415580:PTK2
uniprot id: A0A6P7ZKU1
names: Subcellular Location Annotation
messages: Cell membrane
messages: focal adhesion

1415580:LOC115475753
gene id: 1415580:LOC115475753
uniprot id: A0A6P7YRF9
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

1415580:LOC115479245
gene id: 1415580:LOC115479245
uniprot id: A0A6P7Z8K7
uniprot id: A0A6P7ZBB5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

1415580:C2H18orf32
gene id: 1415580:C2H18orf32
uniprot id: A0A6P7X8I4
names: Similarity
messages: Belongs to the UPF0729 family.

1415580:NKX2-5
gene id: 1415580:NKX2-5
uniprot id: A0A6P7YYR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NK-2 homeobox family.
messages: Nucleus

1415580:LOC115461292
gene id: 1415580:LOC115461292
uniprot id: A0A6P7X9U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:ABCG8
gene id: 1415580:ABCG8
uniprot id: A0A6P7XAV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

1415580:SNX7
gene id: 1415580:SNX7
uniprot id: A0A6P7YI60
names: Similarity
messages: Belongs to the sorting nexin family.

1415580:ADRA1B
gene id: 1415580:ADRA1B
uniprot id: A0A6P7YWE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.
messages: caveola

1415580:TAC3
gene id: 1415580:TAC3
uniprot id: A0A6P7XCX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted

1415580:NT5E
gene id: 1415580:NT5E
uniprot id: A0A6P7XPD0
uniprot id: A0A6P7XWB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-nucleotidase family.
messages: Membrane

1415580:LOC115458158
gene id: 1415580:LOC115458158
uniprot id: A0A6P7WTY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115466739
gene id: 1415580:LOC115466739
uniprot id: A0A6P7XTS9
uniprot id: A0A6P7XUC8
names: Similarity
messages: Belongs to the intermediate filament family.

1415580:LOC115480664
gene id: 1415580:LOC115480664
uniprot id: A0A6P7ZG54
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:TEKT5
gene id: 1415580:TEKT5
uniprot id: A0A6P7YSB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

1415580:HNRNPA3
gene id: 1415580:HNRNPA3
uniprot id: A0A6P7YAU3
names: Subcellular Location Annotation
messages: Nucleus

1415580:TREX2
gene id: 1415580:TREX2
uniprot id: A0A6P7XCE7
names: Similarity
messages: Belongs to the exonuclease superfamily. TREX family.

1415580:PRND
gene id: 1415580:PRND
uniprot id: A0A6P7XSG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prion family.
messages: Cell membrane
messages: Membrane

1415580:ASPH
gene id: 1415580:ASPH
uniprot id: A0A6P7Z0I5
uniprot id: A0A6P7Z1X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.
messages: Membrane

1415580:HOXD10
gene id: 1415580:HOXD10
uniprot id: A0A6P7YHY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

1415580:HOMEZ
gene id: 1415580:HOMEZ
uniprot id: A0A6P7WQ77
names: Subcellular Location Annotation
messages: Nucleus

1415580:MMD2
gene id: 1415580:MMD2
uniprot id: A0A6P7YX57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

1415580:AKAP9
gene id: 1415580:AKAP9
uniprot id: A0A6P7XSJ4
uniprot id: A0A6P7XU27
uniprot id: A0A6P7XZ47
names: Subcellular Location Annotation
messages: centrosome

1415580:GGH
gene id: 1415580:GGH
uniprot id: A0A6P7YUC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C26 family.
messages: extracellular space

1415580:SCAMP3
gene id: 1415580:SCAMP3
uniprot id: A0A6P7WMC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

1415580:LOC115474170
gene id: 1415580:LOC115474170
uniprot id: A0A6P7YK75
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

1415580:FADS1
gene id: 1415580:FADS1
uniprot id: A0A6P7XNV8
uniprot id: A0A6P7XVN4
names: Similarity
messages: Belongs to the fatty acid desaturase type 1 family.

1415580:STMN2
gene id: 1415580:STMN2
uniprot id: A0A6P7YX59
uniprot id: A0A6P7Z7H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the stathmin family.
messages: Cytoplasm
messages: Membrane
messages: lamellipodium

1415580:PHPT1
gene id: 1415580:PHPT1
uniprot id: A0A6P7YCT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the janus family.
messages: Cytoplasm
messages: Exhibits phosphohistidine phosphatase activity.
messages: Monomer.

1415580:AHCYL1
gene id: 1415580:AHCYL1
uniprot id: A0A6P7ZUL7
uniprot id: A0A6P7ZVC4
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

1415580:CXCR5
gene id: 1415580:CXCR5
uniprot id: A0A6P7ZUB9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:TCEANC2
gene id: 1415580:TCEANC2
uniprot id: A0A6P7YF46
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115457286
gene id: 1415580:LOC115457286
uniprot id: A0A6P7WXC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:GSC
gene id: 1415580:GSC
uniprot id: A0A6P7YUN6
names: Subcellular Location Annotation
messages: Nucleus

1415580:VSX1
gene id: 1415580:VSX1
uniprot id: A0A6P7XKA4
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115476188
gene id: 1415580:LOC115476188
uniprot id: A0A6P7YTJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

1415580:FOXN3
gene id: 1415580:FOXN3
uniprot id: A0A6P7YRE8
uniprot id: A0A6P7YZ33
uniprot id: A0A6P7Z1X0
names: Subcellular Location Annotation
messages: Nucleus

1415580:BABAM1
gene id: 1415580:BABAM1
uniprot id: A0A6P7Z9Z5
uniprot id: A0A6P7ZCN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BABAM1 family.
messages: Nucleus

1415580:LOC115478306
gene id: 1415580:LOC115478306
uniprot id: A0A6P7Z7T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

1415580:LOC115479470
gene id: 1415580:LOC115479470
uniprot id: A0A6P7WW72
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1415580:SYK
gene id: 1415580:SYK
uniprot id: A0A6P7X829
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.

1415580:TRPM8
gene id: 1415580:TRPM8
uniprot id: A0A6P7YPM8
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115466426
gene id: 1415580:LOC115466426
uniprot id: A0A6P7XSU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ferritin family.
messages: Oligomer of 24 subunits. The functional molecule is roughly spherical and contains a central cavity into which the polymeric mineral iron core is deposited.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

1415580:MIOX
gene id: 1415580:MIOX
uniprot id: A0A6P7ZBF9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myo-inositol oxygenase family.
messages: Binds 2 iron ions per subunit.
messages: Cytoplasm

1415580:STAB1
gene id: 1415580:STAB1
uniprot id: A0A6P7Y1E6
uniprot id: A0A6P7Y8T2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:LOC115467065
gene id: 1415580:LOC115467065
uniprot id: A0A6P7XPY5
uniprot id: A0A6P7XVV5
names: Similarity
messages: Belongs to the cytochrome P450 family.

1415580:LOC115457217
gene id: 1415580:LOC115457217
uniprot id: A0A6P7WQ51
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115475031
gene id: 1415580:LOC115475031
uniprot id: A0A6P7YTM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115474336
gene id: 1415580:LOC115474336
uniprot id: A0A6P7YLG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

1415580:SUB1
gene id: 1415580:SUB1
uniprot id: A0A6P7X6E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcriptional coactivator PC4 family.
messages: General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
messages: Nucleus

1415580:LOC115476388
gene id: 1415580:LOC115476388
uniprot id: A0A6P7YVF8
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

1415580:LTB4R
gene id: 1415580:LTB4R
uniprot id: A0A6P7WZX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115476435
gene id: 1415580:LOC115476435
uniprot id: A0A6P7YZG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

1415580:STRIP1
gene id: 1415580:STRIP1
uniprot id: A0A6P7ZK05
uniprot id: A0A6P7ZVL6
names: Similarity
messages: Belongs to the STRIP family.

1415580:LOC115474516
gene id: 1415580:LOC115474516
uniprot id: A0A6P7YM62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

1415580:LOC115463407
gene id: 1415580:LOC115463407
uniprot id: A0A6P7X8S7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the annexin family.
messages: Cell membrane
messages: Cytoplasm
messages: Lateral cell membrane
messages: Membrane
messages: Nucleus
messages: The full-length protein can bind eight Ca(2+) ions via the annexin repeats. Calcium binding causes a major conformation change that modifies dimer contacts and leads to surface exposure of the N-terminal phosphorylation sites; in the absence of Ca(2+), these sites are buried in the interior of the protein core. The N-terminal region becomes disordered in response to calcium-binding.
messages: cilium

1415580:CAST
gene id: 1415580:CAST
uniprot id: A0A6P7X152
uniprot id: A0A6P7X9U8
names: Function
names: Similarity
messages: Belongs to the protease inhibitor I27 (calpastatin) family.
messages: Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue.

1415580:MARCHF4
gene id: 1415580:MARCHF4
uniprot id: A0A6P7YR17
names: Subcellular Location Annotation
messages: Membrane

1415580:TEKT1
gene id: 1415580:TEKT1
uniprot id: A0A6P7WES0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

1415580:TACR3
gene id: 1415580:TACR3
uniprot id: A0A6P7WXQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:KLC2
gene id: 1415580:KLC2
uniprot id: A0A6P7Z8R2
uniprot id: A0A6P7ZBJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

1415580:AMD1
gene id: 1415580:AMD1
uniprot id: A0A6P7XRD7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic AdoMetDC family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.

1415580:ESCO1
gene id: 1415580:ESCO1
uniprot id: A0A6P7YN02
uniprot id: A0A6P7YUR6
uniprot id: A0A6P7YZ10
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115463316
gene id: 1415580:LOC115463316
uniprot id: A0A6P7XH31
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

1415580:GPC2
gene id: 1415580:GPC2
uniprot id: A0A6P7WZ06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

1415580:LOC115476134
gene id: 1415580:LOC115476134
uniprot id: A0A6P7YXJ0
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

1415580:LOC115457747
gene id: 1415580:LOC115457747
uniprot id: A0A6P7WY30
uniprot id: A0A6P7WZ37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:ADCYAP1
gene id: 1415580:ADCYAP1
uniprot id: A0A6P7WXU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

1415580:AIFM1
gene id: 1415580:AIFM1
uniprot id: A0A6P7YNX4
uniprot id: A0A6P7YPB5
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

1415580:LOC115465978
gene id: 1415580:LOC115465978
uniprot id: A0A6P7XPZ1
names: Similarity
messages: Belongs to the adenylate kinase family.

1415580:P4HA1
gene id: 1415580:P4HA1
uniprot id: A0A6P7XV25
uniprot id: A0A6P7Y2E9
uniprot id: A0A6P7Y397
uniprot id: A0A6P7Y859
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

1415580:ARAP2
gene id: 1415580:ARAP2
uniprot id: A0A6P7WVD0
uniprot id: A0A6P7X3W0
names: Subcellular Location Annotation
messages: Cytoplasm

1415580:PCK2
gene id: 1415580:PCK2
uniprot id: A0A6P7WRD2
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.

1415580:CHRNB4
gene id: 1415580:CHRNB4
uniprot id: A0A6P7WYJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

1415580:DICER1
gene id: 1415580:DICER1
uniprot id: A0A6P7YYI9
names: Function
names: Similarity
messages: Belongs to the helicase family. Dicer subfamily.
messages: Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, also called RNA interference, controls the elimination of transcripts from mobile and repetitive DNA elements of the genome but also the degradation of exogenous RNA of viral origin for instance. The miRNA pathway on the other side is a mean to specifically regulate the expression of target genes.

1415580:LOC115481919
gene id: 1415580:LOC115481919
uniprot id: A0A6P7ZVJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:PPIL1
gene id: 1415580:PPIL1
uniprot id: A0A6P7ZGP6
uniprot id: A0A6P7ZUK1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1415580:LOC115477749
gene id: 1415580:LOC115477749
uniprot id: A0A6P7Z0D2
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

1415580:LOC115464366
gene id: 1415580:LOC115464366
uniprot id: A0A6P7XDK6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:HOXA1
gene id: 1415580:HOXA1
uniprot id: A0A6P7XS52
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115474687
gene id: 1415580:LOC115474687
uniprot id: A0A6P7YFD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STK11IP family.
messages: Cytoplasm

1415580:MOSPD1
gene id: 1415580:MOSPD1
uniprot id: A0A6P7YEA4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane

1415580:LOC115464647
gene id: 1415580:LOC115464647
uniprot id: A0A6P7XED8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115471198
gene id: 1415580:LOC115471198
uniprot id: A0A6P7YD55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-microseminoprotein family.
messages: Secreted

1415580:YPEL4
gene id: 1415580:YPEL4
uniprot id: A0A6P7WUX5
names: Similarity
messages: Belongs to the yippee family.

1415580:PTK6
gene id: 1415580:PTK6
uniprot id: A0A6P7YKQ4
uniprot id: A0A6P7YTP2
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

1415580:COG6
gene id: 1415580:COG6
uniprot id: A0A6P7XLL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COG6 family.
messages: Component of the conserved oligomeric Golgi complex which is composed of eight different subunits and is required for normal Golgi morphology and localization.
messages: Golgi apparatus membrane
messages: Membrane
messages: Required for normal Golgi function.

1415580:LOC115466841
gene id: 1415580:LOC115466841
uniprot id: A0A6P7XM39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM242 family.
messages: Membrane

1415580:HTR1E
gene id: 1415580:HTR1E
uniprot id: A0A6P7XE63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115463520
gene id: 1415580:LOC115463520
uniprot id: A0A6P7X318
uniprot id: A0A6P7X9H4
uniprot id: A0A6P7XH23
names: Similarity
messages: Belongs to the BicD family.

1415580:LOC115462380
gene id: 1415580:LOC115462380
uniprot id: A0A6P7WYC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:FAM124B
gene id: 1415580:FAM124B
uniprot id: A0A6P7Z682
uniprot id: A0A6P7Z687
uniprot id: A0A6P7Z9N0
uniprot id: A0A6P7Z9N5
names: Similarity
messages: Belongs to the FAM124 family.

1415580:NEDD9
gene id: 1415580:NEDD9
uniprot id: A0A6P7YUD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

1415580:INTS8
gene id: 1415580:INTS8
uniprot id: A0A6P7Z005
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 8 family.
messages: Nucleus

1415580:BMP2
gene id: 1415580:BMP2
uniprot id: A0A6P7XKM0
names: Similarity
messages: Belongs to the TGF-beta family.

1415580:HAGHL
gene id: 1415580:HAGHL
uniprot id: A0A6P7YL84
uniprot id: A0A6P7YT99
uniprot id: A0A6P7YTA3
uniprot id: A0A6P7YU52
uniprot id: A0A6P7YY29
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

1415580:SEC24C
gene id: 1415580:SEC24C
uniprot id: A0A6P7Y345
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

1415580:GPD1L
gene id: 1415580:GPD1L
uniprot id: A0A6P7WXK6
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

1415580:LOC115464970
gene id: 1415580:LOC115464970
uniprot id: A0A6P7X6J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

1415580:GPC3
gene id: 1415580:GPC3
uniprot id: A0A6P7YRC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

1415580:ASF1B
gene id: 1415580:ASF1B
uniprot id: A0A6P7XKI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

1415580:HBP1
gene id: 1415580:HBP1
uniprot id: A0A6P7Z6C3
uniprot id: A0A6P7Z905
uniprot id: A0A6P7Z9R1
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

1415580:LOC115473459
gene id: 1415580:LOC115473459
uniprot id: A0A6P7YMC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.
messages: Cytoplasm

1415580:PALM
gene id: 1415580:PALM
uniprot id: A0A6P7ZAI4
uniprot id: A0A6P7ZDW5
names: Similarity
messages: Belongs to the paralemmin family.

1415580:LOC115462862
gene id: 1415580:LOC115462862
uniprot id: A0A6P7WZS6
names: Similarity
messages: Belongs to the YOS1 family.

1415580:DCT
gene id: 1415580:DCT
uniprot id: A0A6P7XSA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

1415580:LPAR4
gene id: 1415580:LPAR4
uniprot id: A0A6P7YRZ0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:KYNU
gene id: 1415580:KYNU
uniprot id: A0A6P7YKT1
uniprot id: A0A6P7YQS6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115457440
gene id: 1415580:LOC115457440
uniprot id: A0A6P7WWT5
names: Similarity
messages: Belongs to the copper type II ascorbate-dependent monooxygenase family.

1415580:SNAP47
gene id: 1415580:SNAP47
uniprot id: A0A6P7XC24
names: Similarity
messages: Belongs to the SVAP1 family.

1415580:PCMTD1
gene id: 1415580:PCMTD1
uniprot id: A0A6P7YSM8
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1415580:TNNI3
gene id: 1415580:TNNI3
uniprot id: A0A6P7XFM3
names: Function
names: Similarity
messages: Belongs to the troponin I family.
messages: Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

1415580:LOC115462016
gene id: 1415580:LOC115462016
uniprot id: A0A6P7XCN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

1415580:LOC115481865
gene id: 1415580:LOC115481865
uniprot id: A0A6P7ZVE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

1415580:ANO8
gene id: 1415580:ANO8
uniprot id: A0A6P7ZND4
uniprot id: A0A6P7ZPZ4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:BMX
gene id: 1415580:BMX
uniprot id: A0A6P7Y4Y6
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

1415580:CHD5
gene id: 1415580:CHD5
uniprot id: A0A6P7ZG80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

1415580:SLITRK2
gene id: 1415580:SLITRK2
uniprot id: A0A6P7YQ62
names: Similarity
messages: Belongs to the SLITRK family.

1415580:LOC115464756
gene id: 1415580:LOC115464756
uniprot id: A0A6P7XK20
names: Similarity
messages: Belongs to the SMAP family.

1415580:DHX8
gene id: 1415580:DHX8
uniprot id: A0A6P7ZC66
uniprot id: A0A6P7ZV00
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115482278
gene id: 1415580:LOC115482278
uniprot id: A0A6P7ZVN4
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

1415580:KDELR2
gene id: 1415580:KDELR2
uniprot id: A0A6P7YJP4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:LOC115464270
gene id: 1415580:LOC115464270
uniprot id: A0A6P7XDC9
names: Similarity
messages: Belongs to the peptidase C2 family.

1415580:SDC1
gene id: 1415580:SDC1
uniprot id: A0A6P7XGQ6
uniprot id: A0A6P7XQ70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane
messages: extracellular exosome

1415580:USP3
gene id: 1415580:USP3
uniprot id: A0A6P7WLA6
uniprot id: A0A6P7WSB7
uniprot id: A0A6P7WSD5
names: Similarity
messages: Belongs to the peptidase C19 family.

1415580:LOC115461472
gene id: 1415580:LOC115461472
uniprot id: A0A6P7X9A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

1415580:LOC115463515
gene id: 1415580:LOC115463515
uniprot id: A0A6P7XH13
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

1415580:KIF3B
gene id: 1415580:KIF3B
uniprot id: A0A6P7YTA5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

1415580:DXO
gene id: 1415580:DXO
uniprot id: A0A6P7XRX5
uniprot id: A0A6P7XRY1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DXO/Dom3Z family.
messages: Binds 2 magnesium ions.
messages: Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
messages: Nucleus

1415580:STAB2
gene id: 1415580:STAB2
uniprot id: A0A6P7YZA4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:CDK2AP2
gene id: 1415580:CDK2AP2
uniprot id: A0A6P7WF91
names: Similarity
messages: Belongs to the CDK2AP family.

1415580:LOC115464672
gene id: 1415580:LOC115464672
uniprot id: A0A6P7XKQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:CLIP1
gene id: 1415580:CLIP1
uniprot id: A0A6P7Z314
uniprot id: A0A6P7Z878
uniprot id: A0A6P7ZAY5
uniprot id: A0A6P7ZDP9
uniprot id: A0A6P7ZDQ5
uniprot id: A0A6P7ZE99
names: Subcellular Location Annotation
messages: cytoskeleton

1415580:VTA1
gene id: 1415580:VTA1
uniprot id: A0A6P7XP99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTA1 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

1415580:THOP1
gene id: 1415580:THOP1
uniprot id: A0A6P7Z6T6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1415580:NF2
gene id: 1415580:NF2
uniprot id: A0A6P7ZEE8
uniprot id: A0A6P7ZI43
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

1415580:LOC115481732
gene id: 1415580:LOC115481732
uniprot id: A0A6P7ZC76
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.

1415580:SLC8A1
gene id: 1415580:SLC8A1
uniprot id: A0A6P7X884
uniprot id: A0A6P7XM80
uniprot id: A0A6P7XMZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

1415580:LBR
gene id: 1415580:LBR
uniprot id: A0A6P7XED0
uniprot id: A0A6P7XMG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus inner membrane

1415580:ATP6V1G3
gene id: 1415580:ATP6V1G3
uniprot id: A0A6P7YKS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

1415580:EIF3I
gene id: 1415580:EIF3I
uniprot id: A0A6P7ZL34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

1415580:LOC115478360
gene id: 1415580:LOC115478360
uniprot id: A0A6P7YWM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 12 family.
messages: Nucleus

1415580:LOC115463598
gene id: 1415580:LOC115463598
uniprot id: A0A6P7X3G3
uniprot id: A0A6P7X9Y4
uniprot id: A0A6P7XC75
uniprot id: A0A6P7XHH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

1415580:SPICE1
gene id: 1415580:SPICE1
uniprot id: A0A6P7XWF5
uniprot id: A0A6P7Y3T1
uniprot id: A0A6P7Y4E9
uniprot id: A0A6P7YAA3
names: Subcellular Location Annotation
messages: centriole
messages: spindle

1415580:LOC115475955
gene id: 1415580:LOC115475955
uniprot id: A0A6P7YT68
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:NT5DC3
gene id: 1415580:NT5DC3
uniprot id: A0A6P7Z452
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

1415580:DDX49
gene id: 1415580:DDX49
uniprot id: A0A6P7ZBX6
uniprot id: A0A6P7ZCT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family.
messages: Cytoplasm

1415580:LOC115478988
gene id: 1415580:LOC115478988
uniprot id: A0A6P7ZAW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM10 family.
messages: Nucleus

1415580:SEMA3A
gene id: 1415580:SEMA3A
uniprot id: A0A6P7Z3G7
uniprot id: A0A6P7Z898
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115456973
gene id: 1415580:LOC115456973
uniprot id: A0A6P7WMF4
names: Subcellular Location Annotation
messages: Membrane

1415580:HECTD1
gene id: 1415580:HECTD1
uniprot id: A0A6P7Z3H0
names: Function
names: Similarity
messages: Belongs to the UPL family. K-HECT subfamily.
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

1415580:LOC115461502
gene id: 1415580:LOC115461502
uniprot id: A0A6P7X9F6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

1415580:LOC115464409
gene id: 1415580:LOC115464409
uniprot id: A0A6P7XBH3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:KPNA4
gene id: 1415580:KPNA4
uniprot id: A0A6P7Z784
names: Similarity
messages: Belongs to the importin alpha family.

1415580:LOC115462811
gene id: 1415580:LOC115462811
uniprot id: A0A6P7X897
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the aldo/keto reductase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

1415580:C1QBP
gene id: 1415580:C1QBP
uniprot id: A0A6P7WN91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAM33 family.
messages: Cell membrane

1415580:GABRB2
gene id: 1415580:GABRB2
uniprot id: A0A6P7YWK9
uniprot id: A0A6P7YWT7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

1415580:KCNH7
gene id: 1415580:KCNH7
uniprot id: A0A6P7YMA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv11.1/KCNH2 sub-subfamily.
messages: Membrane

1415580:RABAC1
gene id: 1415580:RABAC1
uniprot id: A0A6P7YSZ2
uniprot id: A0A6P7YXS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

1415580:LOC115470793
gene id: 1415580:LOC115470793
uniprot id: A0A6P7XXN9
uniprot id: A0A6P7Y583
uniprot id: A0A6P7YAW5
uniprot id: A0A6P7YBH4
uniprot id: A0A6P7YBH9
names: Similarity
messages: Belongs to the SNF2/RAD54 helicase family.

1415580:LOC115474988
gene id: 1415580:LOC115474988
uniprot id: A0A6P7YTJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115474705
gene id: 1415580:LOC115474705
uniprot id: A0A6P7YME1
uniprot id: A0A6P7YN61
uniprot id: A0A6P7YSJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIP1 family.
messages: Nucleus

1415580:CNIH4
gene id: 1415580:CNIH4
uniprot id: A0A6P7XIK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

1415580:LOC115475983
gene id: 1415580:LOC115475983
uniprot id: A0A6P7YSI6
names: Similarity
messages: Belongs to the pectinacetylesterase family. Notum subfamily.

1415580:PTAR1
gene id: 1415580:PTAR1
uniprot id: A0A6P7X2C5
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

1415580:LOC115482384
gene id: 1415580:LOC115482384
uniprot id: A0A6P7ZF81
names: Subcellular Location Annotation
messages: Membrane

1415580:C4BPB
gene id: 1415580:C4BPB
uniprot id: A0A6P7ZB57
uniprot id: A0A6P7ZNF9
uniprot id: A0A6P7ZU31
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115480110
gene id: 1415580:LOC115480110
uniprot id: A0A6P7ZFT2
names: Similarity
messages: Belongs to the cornifelin family.

1415580:SELENOF
gene id: 1415580:SELENOF
uniprot id: A0A6P7Y0Y9
names: Similarity
messages: Belongs to the selenoprotein M/F family.

1415580:LOC115479611
gene id: 1415580:LOC115479611
uniprot id: A0A6P7ZD08
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1415580:FAM53A
gene id: 1415580:FAM53A
uniprot id: A0A6P7WUW4
names: Similarity
messages: Belongs to the FAM53 family.

1415580:TJP3
gene id: 1415580:TJP3
uniprot id: A0A6P7ZB44
uniprot id: A0A6P7ZH85
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: tight junction

1415580:CAPN7
gene id: 1415580:CAPN7
uniprot id: A0A6P7Y3T2
names: Similarity
messages: Belongs to the peptidase C2 family.

1415580:XKR6
gene id: 1415580:XKR6
uniprot id: A0A6P7XVS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

1415580:MRPL58
gene id: 1415580:MRPL58
uniprot id: A0A6P7YM98
names: Subcellular Location Annotation
messages: Mitochondrion

1415580:SEMA5B
gene id: 1415580:SEMA5B
uniprot id: A0A6P7YKC7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115457109
gene id: 1415580:LOC115457109
uniprot id: A0A6P7WPT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:EXOC7
gene id: 1415580:EXOC7
uniprot id: A0A6P7Y9C1
uniprot id: A0A6P7YGL3
uniprot id: A0A6P7YGL6
uniprot id: A0A6P7YLT6
uniprot id: A0A6P7YM05
names: Function
names: Similarity
messages: Belongs to the EXO70 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

1415580:CDK2AP1
gene id: 1415580:CDK2AP1
uniprot id: A0A6P7ZGD7
uniprot id: A0A6P7ZMS4
names: Similarity
messages: Belongs to the CDK2AP family.

1415580:SH3RF1
gene id: 1415580:SH3RF1
uniprot id: A0A6P7X247
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3RF family.
messages: lamellipodium
messages: perinuclear region
messages: trans-Golgi network

1415580:TMEM132B
gene id: 1415580:TMEM132B
uniprot id: A0A6P7ZCM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

1415580:CPLX1
gene id: 1415580:CPLX1
uniprot id: A0A6P7XIW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

1415580:DDC
gene id: 1415580:DDC
uniprot id: A0A6P7YD41
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

1415580:LOC115456473
gene id: 1415580:LOC115456473
uniprot id: A0A6P7WU85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

1415580:EIF3D
gene id: 1415580:EIF3D
uniprot id: A0A6P7YM67
uniprot id: A0A6P7YRM1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit D family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Cytoplasm
messages: The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.

1415580:SFXN2
gene id: 1415580:SFXN2
uniprot id: A0A6P7Y7H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane
messages: Mitochondrion membrane

1415580:TRRAP
gene id: 1415580:TRRAP
uniprot id: A0A6P7YY32
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. TRA1 subfamily.

1415580:ALDOB
gene id: 1415580:ALDOB
uniprot id: A0A6P7ZW14
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

1415580:FSHB
gene id: 1415580:FSHB
uniprot id: A0A6P7XXX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

1415580:LOC115457902
gene id: 1415580:LOC115457902
uniprot id: A0A6P7WSS4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Secreted

1415580:LOC115468216
gene id: 1415580:LOC115468216
uniprot id: A0A6P7XY14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

1415580:SNX10
gene id: 1415580:SNX10
uniprot id: A0A6P7XRW0
uniprot id: A0A6P7XRX0
uniprot id: A0A6P7XRY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

1415580:PPARGC1A
gene id: 1415580:PPARGC1A
uniprot id: A0A6P7WVA2
uniprot id: A0A6P7X3S1
names: Subcellular Location Annotation
messages: PML body

1415580:LYRM2
gene id: 1415580:LYRM2
uniprot id: A0A6P7X9K6
names: Similarity
messages: Belongs to the complex I LYR family.

1415580:BGN
gene id: 1415580:BGN
uniprot id: A0A6P7X2W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: May be involved in collagen fiber assembly.
messages: extracellular matrix

1415580:WDPCP
gene id: 1415580:WDPCP
uniprot id: A0A6P7XHT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat fritz family.
messages: Cell membrane
messages: Membrane
messages: cilium axoneme

1415580:CENPV
gene id: 1415580:CENPV
uniprot id: A0A6P7ZFE1
uniprot id: A0A6P7ZLK2
uniprot id: A0A6P7ZVH3
names: Similarity
messages: Belongs to the Gfa family.

1415580:LOC115475357
gene id: 1415580:LOC115475357
uniprot id: A0A6P7YUD7
names: Similarity
messages: Belongs to the S-100 family.

1415580:OXR1
gene id: 1415580:OXR1
uniprot id: A0A6P7Z8K6
uniprot id: A0A6P7ZBD0
names: Similarity
messages: Belongs to the OXR1 family.

1415580:MDM4
gene id: 1415580:MDM4
uniprot id: A0A6P7ZC51
uniprot id: A0A6P7ZQ10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain.
messages: Nucleus

1415580:KIF1C
gene id: 1415580:KIF1C
uniprot id: A0A6P7WXX4
uniprot id: A0A6P7WYW8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

1415580:TCTN1
gene id: 1415580:TCTN1
uniprot id: A0A6P7Z9D1
uniprot id: A0A6P7ZJ58
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

1415580:NKX6-3
gene id: 1415580:NKX6-3
uniprot id: A0A6P7XY98
names: Subcellular Location Annotation
messages: Nucleus

1415580:CCNA1
gene id: 1415580:CCNA1
uniprot id: A0A6P7XQ69
names: Similarity
messages: Belongs to the cyclin family.

1415580:LAMP3
gene id: 1415580:LAMP3
uniprot id: A0A6P7YZE5
uniprot id: A0A6P7Z511
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane

1415580:DCAF1
gene id: 1415580:DCAF1
uniprot id: A0A6P7Y1N9
uniprot id: A0A6P7Y8W4
uniprot id: A0A6P7Y923
uniprot id: A0A6P7YF39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPRBP/DCAF1 family.
messages: Nucleus

1415580:LOC115457031
gene id: 1415580:LOC115457031
uniprot id: A0A6P7WWN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:KCNH5
gene id: 1415580:KCNH5
uniprot id: A0A6P7YV39
names: Subcellular Location Annotation
messages: Membrane

1415580:EXOC3L1
gene id: 1415580:EXOC3L1
uniprot id: A0A6P7Y933
names: Similarity
messages: Belongs to the SEC6 family.

1415580:NCAN
gene id: 1415580:NCAN
uniprot id: A0A6P7Z8U9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:ELOC
gene id: 1415580:ELOC
uniprot id: A0A6P7Z4B8
names: Similarity
messages: Belongs to the SKP1 family.

1415580:LOC115465392
gene id: 1415580:LOC115465392
uniprot id: A0A6P7X7Z4
uniprot id: A0A6P7XMQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Stoned B family.
messages: Cytoplasm

1415580:LOC115477078
gene id: 1415580:LOC115477078
uniprot id: A0A6P7Z1A2
names: Similarity
messages: Belongs to the DeSI family.

1415580:SPCS2
gene id: 1415580:SPCS2
uniprot id: A0A6P7XTM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS2 family.
messages: Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site.
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:LOC115471258
gene id: 1415580:LOC115471258
uniprot id: A0A6P7YDB8
names: Subcellular Location Annotation
messages: Nucleus

1415580:MAT2B
gene id: 1415580:MAT2B
uniprot id: A0A6P7YQG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family. MAT2B subfamily.
messages: Heterotrimer; composed of a catalytic MAT2A homodimer that binds one regulatory MAT2B chain. Heterohexamer; composed of a central, catalytic MAT2A homotetramer flanked on either side by a regulatory MAT2B chain. NADP binding increases the affinity for MAT2A.
messages: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.

1415580:DGKE
gene id: 1415580:DGKE
uniprot id: A0A6P7YMF1
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

1415580:LOC115469674
gene id: 1415580:LOC115469674
uniprot id: A0A6P7XZK9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:BCL2L10
gene id: 1415580:BCL2L10
uniprot id: A0A6P7X4X4
names: Similarity
messages: Belongs to the Bcl-2 family.

1415580:VWF
gene id: 1415580:VWF
uniprot id: A0A6P7Z7P7
names: Subcellular Location Annotation
names: Subunit
messages: Multimeric. Interacts with F8.
messages: extracellular matrix

1415580:LOC115475558
gene id: 1415580:LOC115475558
uniprot id: A0A6P7YID3
names: Similarity
messages: Belongs to the heme oxygenase family.

1415580:CDC25B
gene id: 1415580:CDC25B
uniprot id: A0A6P7WUL9
uniprot id: A0A6P7X321
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

1415580:ATP6V0A1
gene id: 1415580:ATP6V0A1
uniprot id: A0A6P7ZUL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

1415580:IHH
gene id: 1415580:IHH
uniprot id: A0A6P7YSC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: Secreted
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

1415580:ADCK1
gene id: 1415580:ADCK1
uniprot id: A0A6P7YVR5
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

1415580:LOC115482298
gene id: 1415580:LOC115482298
uniprot id: A0A6P7ZV22
uniprot id: A0A6P7ZVR3
names: Similarity
messages: Belongs to the TMEM176 family.

1415580:FMN1
gene id: 1415580:FMN1
uniprot id: A0A6P7YZW2
uniprot id: A0A6P7Z2T0
names: Similarity
messages: Belongs to the formin homology family. Cappuccino subfamily.

1415580:NPM1
gene id: 1415580:NPM1
uniprot id: A0A6P7YU71
uniprot id: A0A6P7YY44
names: Similarity
messages: Belongs to the nucleoplasmin family.

1415580:LOC115480159
gene id: 1415580:LOC115480159
uniprot id: A0A6P7ZAB5
names: Similarity
messages: Belongs to the THADA family.

1415580:CNIH2
gene id: 1415580:CNIH2
uniprot id: A0A6P7Z5K6
uniprot id: A0A6P7ZAI9
uniprot id: A0A6P7ZDP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

1415580:LOC115461850
gene id: 1415580:LOC115461850
uniprot id: A0A6P7X307
names: Similarity
messages: Belongs to the SKI family.

1415580:YPEL1
gene id: 1415580:YPEL1
uniprot id: A0A6P7Z9P0
names: Similarity
messages: Belongs to the yippee family.

1415580:LOC115457369
gene id: 1415580:LOC115457369
uniprot id: A0A6P7WHA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:MED8
gene id: 1415580:MED8
uniprot id: A0A6P7YEZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 8 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins.
messages: Component of the Mediator complex.
messages: Nucleus

1415580:PDE8A
gene id: 1415580:PDE8A
uniprot id: A0A6P7X5Q2
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

1415580:GTF2H3
gene id: 1415580:GTF2H3
uniprot id: A0A6P7Z8P3
uniprot id: A0A6P7ZDA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB4 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
messages: Nucleus
messages: Part of a TFIID-containing RNA polymerase II pre-initiation complex that is composed of TBP and at least GTF2A1, GTF2A2, GTF2E1, GTF2E2, GTF2F1, GTF2H2, GTF2H3, GTF2H4, GTF2H5, GTF2B, TCEA1, ERCC2, ERCC3, TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. Component of the 7-subunit TFIIH core complex composed of XPB/ERCC3, XPD/ERCC2, GTF2H1, GTF2H2, GTF2H3, GTF2H4 and GTF2H5, which is active in NER. The core complex associates with the 3-subunit CDK-activating kinase (CAK) module composed of CCNH/cyclin H, CDK7 and MNAT1 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription. Interacts with RARA; the interaction requires prior phosphorylation of RARA on 'Ser-369' which then enhances interaction of RARA with CDK7.

1415580:LOC115477404
gene id: 1415580:LOC115477404
uniprot id: A0A6P7YYV6
names: Similarity
messages: Belongs to the peptidase A1 family.

1415580:SHMT1
gene id: 1415580:SHMT1
uniprot id: A0A6P7YXA6
uniprot id: A0A6P7Z0A2
uniprot id: A0A6P7Z105
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

1415580:LOC115476798
gene id: 1415580:LOC115476798
uniprot id: A0A6P7Z1A1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:TOP2B
gene id: 1415580:TOP2B
uniprot id: A0A6P7YFC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Homodimer.
messages: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand.
messages: nucleolus
messages: nucleoplasm

1415580:SLC13A1
gene id: 1415580:SLC13A1
uniprot id: A0A6P7ZB23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

1415580:ALAS1
gene id: 1415580:ALAS1
uniprot id: A0A6P7Y952
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane

1415580:ACAP2
gene id: 1415580:ACAP2
uniprot id: A0A6P7Z0Y6
uniprot id: A0A6P7Z6A0
uniprot id: A0A6P7Z6A2
uniprot id: A0A6P7Z8T5
uniprot id: A0A6P7ZCB3
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

1415580:NFRKB
gene id: 1415580:NFRKB
uniprot id: A0A6P7ZG65
names: Subcellular Location Annotation
messages: Nucleus

1415580:NAA40
gene id: 1415580:NAA40
uniprot id: A0A6P7Z5K1
uniprot id: A0A6P7ZGP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA40 subfamily.
messages: Cytoplasm
messages: Nucleus

1415580:PNN
gene id: 1415580:PNN
uniprot id: A0A6P7YTG7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pinin family.
messages: Found in a mRNA splicing-dependent exon junction complex (EJC). Found in a complex with SR proteins. Found in a mRNP complex with RNPS1. Component of the PSAP complex consisting of RNPS1, SAP18 and PNN. Interacts with PNISR, CTBP1, CTBP2, KRT8, KRT18, KRT19, PS1D/PNO40, PPIG, RNPS1, SFRS4 and SRRM2. Identified in the spliceosome C complex.
messages: Nucleus speckle
messages: desmosome

1415580:SCOC
gene id: 1415580:SCOC
uniprot id: A0A6P7X520
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCOC family.
messages: Positive regulator of amino acid starvation-induced autophagy.
messages: trans-Golgi network

1415580:VIM
gene id: 1415580:VIM
uniprot id: A0A6P7XSC6
names: Function
names: Similarity
messages: Belongs to the intermediate filament family.
messages: Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.

1415580:PIM3
gene id: 1415580:PIM3
uniprot id: A0A6P7YYS4
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

1415580:GBF1
gene id: 1415580:GBF1
uniprot id: A0A6P7XUU4
names: Subcellular Location Annotation
messages: Golgi apparatus

1415580:PIK3IP1
gene id: 1415580:PIK3IP1
uniprot id: A0A6P7ZNL8
uniprot id: A0A6P7ZQN6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:RRP12
gene id: 1415580:RRP12
uniprot id: A0A6P7XTH5
names: Similarity
messages: Belongs to the RRP12 family.

1415580:SLC1A7
gene id: 1415580:SLC1A7
uniprot id: A0A6P7Y2W7
uniprot id: A0A6P7Y9Y9
uniprot id: A0A6P7YFI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1415580:MAF1
gene id: 1415580:MAF1
uniprot id: A0A6P7ZUQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAF1 family.
messages: Element of the TORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.
messages: Nucleus

1415580:MRPL19
gene id: 1415580:MRPL19
uniprot id: A0A6P7XGM7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.

1415580:LOC115477754
gene id: 1415580:LOC115477754
uniprot id: A0A6P7Z4L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.5/KCNA5 sub-subfamily.
messages: Cell membrane
messages: Membrane

1415580:NTF3
gene id: 1415580:NTF3
uniprot id: A0A6P7YUP2
uniprot id: A0A6P7Z0Y8
uniprot id: A0A6P7Z590
uniprot id: A0A6P7Z659
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Secreted
messages: Seems to promote the survival of visceral and proprioceptive sensory neurons.

1415580:CLRN3
gene id: 1415580:CLRN3
uniprot id: A0A6P7XZ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

1415580:RTN4
gene id: 1415580:RTN4
uniprot id: A0A6P7X817
uniprot id: A0A6P7XES5
uniprot id: A0A6P7XGX2
uniprot id: A0A6P7XM11
uniprot id: A0A6P7XM16
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:SLC6A4
gene id: 1415580:SLC6A4
uniprot id: A0A6P7WMN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A4 subfamily.
messages: Cell membrane
messages: Endomembrane system
messages: Endosome membrane
messages: Membrane
messages: Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner.
messages: Synapse
messages: focal adhesion

1415580:WDR83OS
gene id: 1415580:WDR83OS
uniprot id: A0A6P7XQV9
names: Similarity
messages: Belongs to the Asterix family.

1415580:DKK2
gene id: 1415580:DKK2
uniprot id: A0A6P7X7G6
names: Similarity
messages: Belongs to the dickkopf family.

1415580:CNFN
gene id: 1415580:CNFN
uniprot id: A0A6P7YYW5
names: Similarity
messages: Belongs to the cornifelin family.

1415580:LOC115469672
gene id: 1415580:LOC115469672
uniprot id: A0A6P7Y6E2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115460543
gene id: 1415580:LOC115460543
uniprot id: A0A6P7X114
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115457555
gene id: 1415580:LOC115457555
uniprot id: A0A6P7WX81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:RABEP1
gene id: 1415580:RABEP1
uniprot id: A0A6P7ZGG8
uniprot id: A0A6P7ZW63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rabaptin family.
messages: Cytoplasm
messages: Early endosome
messages: Endosome

1415580:ISYNA1
gene id: 1415580:ISYNA1
uniprot id: A0A6P7Z9M6
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1415580:LOC115467375
gene id: 1415580:LOC115467375
uniprot id: A0A6P7XHY5
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1415580:YRDC
gene id: 1415580:YRDC
uniprot id: A0A6P7ZC21
names: Similarity
messages: Belongs to the SUA5 family.

1415580:LOC115481891
gene id: 1415580:LOC115481891
uniprot id: A0A6P7ZH59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115457108
gene id: 1415580:LOC115457108
uniprot id: A0A6P7WMT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:NUDT12
gene id: 1415580:NUDT12
uniprot id: A0A6P7X7N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Cytoplasmic granule
messages: Peroxisome

1415580:LOC115465629
gene id: 1415580:LOC115465629
uniprot id: A0A6P7X933
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PET117 family.
messages: Mitochondrion

1415580:ELP5
gene id: 1415580:ELP5
uniprot id: A0A6P7X0S2
uniprot id: A0A6P7X1Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP5 family.
messages: Cytoplasm
messages: Nucleus

1415580:LOC115466340
gene id: 1415580:LOC115466340
uniprot id: A0A6P7XCU4
uniprot id: A0A6P7XCU6
uniprot id: A0A6P7XJL2
uniprot id: A0A6P7XLJ7
uniprot id: A0A6P7XLK2
uniprot id: A0A6P7XRT3
uniprot id: A0A6P7XSI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

1415580:GORASP2
gene id: 1415580:GORASP2
uniprot id: A0A6P7YIQ7
names: Similarity
messages: Belongs to the GORASP family.

1415580:SLC5A1
gene id: 1415580:SLC5A1
uniprot id: A0A6P7ZID8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1415580:LOC115457837
gene id: 1415580:LOC115457837
uniprot id: A0A6P7WZI9
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115457177
gene id: 1415580:LOC115457177
uniprot id: A0A6P7WN36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:BCAR1
gene id: 1415580:BCAR1
uniprot id: A0A6P7Y9P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

1415580:SLC26A5
gene id: 1415580:SLC26A5
uniprot id: A0A6P7Z3M3
uniprot id: A0A6P7Z5T4
uniprot id: A0A6P7Z8G1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:PPDPFL
gene id: 1415580:PPDPFL
uniprot id: A0A6P7Z3R8
names: Similarity
messages: Belongs to the PPDPF family.

1415580:SLC48A1
gene id: 1415580:SLC48A1
uniprot id: A0A6P7XNN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRG family.
messages: Endosome membrane
messages: Heme transporter that regulates intracellular heme availability through the endosomal or lysosomal compartment.
messages: Lysosome membrane
messages: Membrane

1415580:GPBP1L1
gene id: 1415580:GPBP1L1
uniprot id: A0A6P7Y257
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus

1415580:SLC45A3
gene id: 1415580:SLC45A3
uniprot id: A0A6P7ZUI0
uniprot id: A0A6P7ZUI8
names: Subcellular Location Annotation
messages: Membrane

1415580:MCMDC2
gene id: 1415580:MCMDC2
uniprot id: A0A6P7WS65
names: Similarity
messages: Belongs to the MCM family.

1415580:C13H1orf174
gene id: 1415580:C13H1orf174
uniprot id: A0A6P7WL22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0688 family.
messages: Nucleus

1415580:PHYHIPL
gene id: 1415580:PHYHIPL
uniprot id: A0A6P7Y6T6
uniprot id: A0A6P7YCY1
names: Similarity
messages: Belongs to the PHYHIP family.

1415580:SGCB
gene id: 1415580:SGCB
uniprot id: A0A6P7X9H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
messages: Cross-link to form 2 major subcomplexes: one consisting of SGCB, SGCD and SGCG and the other consisting of SGCB and SGCD. The association between SGCB and SGCG is particularly strong while SGCA is loosely associated with the other sarcoglycans.
messages: cytoskeleton
messages: sarcolemma

1415580:LOC115464405
gene id: 1415580:LOC115464405
uniprot id: A0A6P7XDN9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LOC115464705
gene id: 1415580:LOC115464705
uniprot id: A0A6P7XEK6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:THOC6
gene id: 1415580:THOC6
uniprot id: A0A6P7YIE4
uniprot id: A0A6P7YNY7
names: Similarity
messages: Belongs to the WD repeat THOC6 family.

1415580:HSDL1
gene id: 1415580:HSDL1
uniprot id: A0A6P7Y3V5
uniprot id: A0A6P7Y9Q0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1415580:TNRC6B
gene id: 1415580:TNRC6B
uniprot id: A0A6P7YG78
names: Similarity
messages: Belongs to the GW182 family.

1415580:TRIM71
gene id: 1415580:TRIM71
uniprot id: A0A6P7X6U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIM/RBCC family.
messages: Cytoplasm

1415580:LOC115482561
gene id: 1415580:LOC115482561
uniprot id: A0A6P7ZG30
uniprot id: A0A6P7ZG37
uniprot id: A0A6P7ZMX5
uniprot id: A0A6P7ZVZ3
uniprot id: A0A6P7ZVZ8
uniprot id: A0A6P7ZWP3
uniprot id: A0A6P8A025
names: Similarity
messages: Belongs to the N-CoR nuclear receptor corepressors family.

1415580:HADH
gene id: 1415580:HADH
uniprot id: A0A6P7X955
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1415580:LOC115461833
gene id: 1415580:LOC115461833
uniprot id: A0A6P7WX18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1415580:ABCC2
gene id: 1415580:ABCC2
uniprot id: A0A6P7Y6P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

1415580:LOC115457174
gene id: 1415580:LOC115457174
uniprot id: A0A6P7WGS6
names: Subcellular Location Annotation
messages: Membrane

1415580:FAM131B
gene id: 1415580:FAM131B
uniprot id: A0A6P7WS28
uniprot id: A0A6P7X0C4
names: Similarity
messages: Belongs to the FAM131 family.

1415580:SLC16A7
gene id: 1415580:SLC16A7
uniprot id: A0A6P7ZC44
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cytoplasm
messages: Membrane

1415580:LOC115482473
gene id: 1415580:LOC115482473
uniprot id: A0A6P7ZFI1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

1415580:LOC115462898
gene id: 1415580:LOC115462898
uniprot id: A0A6P7WZY1
names: Similarity
names: Subunit
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Ribosomal protein S27a is part of the 40S ribosomal subunit.

1415580:LOC115469718
gene id: 1415580:LOC115469718
uniprot id: A0A6P7Y5I4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115464842
gene id: 1415580:LOC115464842
uniprot id: A0A6P7XKA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115482601
gene id: 1415580:LOC115482601
uniprot id: A0A6P8A0L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the claudin family.
messages: Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN1 and CLDN2 homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

1415580:LOC115464449
gene id: 1415580:LOC115464449
uniprot id: A0A6P7XDT3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:PRMT7
gene id: 1415580:PRMT7
uniprot id: A0A6P7Y5D8
uniprot id: A0A6P7YBE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.
messages: Nucleus
messages: cytosol

1415580:LOC115460056
gene id: 1415580:LOC115460056
uniprot id: A0A6P7WZU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Cytoplasm
messages: Nucleus
messages: Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.

1415580:HRH2
gene id: 1415580:HRH2
uniprot id: A0A6P7YUQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:MFN2
gene id: 1415580:MFN2
uniprot id: A0A6P7ZW60
uniprot id: A0A6P7ZYN9
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

1415580:DUSP16
gene id: 1415580:DUSP16
uniprot id: A0A6P7Z4H1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

1415580:LOC115471229
gene id: 1415580:LOC115471229
uniprot id: A0A6P7Y738
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Nucleus

1415580:DPH1
gene id: 1415580:DPH1
uniprot id: A0A6P7WKV6
uniprot id: A0A6P7WTS7
uniprot id: A0A6P7WUT6
names: Similarity
messages: Belongs to the DPH1/DPH2 family. DPH1 subfamily.

1415580:CACNA2D3
gene id: 1415580:CACNA2D3
uniprot id: A0A6P7Y8P2
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

1415580:NUDT1
gene id: 1415580:NUDT1
uniprot id: A0A6P7YUN3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Monomer.
messages: Nucleus

1415580:CALR
gene id: 1415580:CALR
uniprot id: A0A6P7XR04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calreticulin family.
messages: Endoplasmic reticulum lumen

1415580:CAPN3
gene id: 1415580:CAPN3
uniprot id: A0A6P7YVA1
uniprot id: A0A6P7Z1I4
uniprot id: A0A6P7Z312
uniprot id: A0A6P7Z5U6
uniprot id: A0A6P7Z5V2
uniprot id: A0A6P7Z6Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C2 family.
messages: Calcium-regulated non-lysosomal thiol-protease.
messages: Cytoplasm
messages: Homodimer.
messages: nucleolus

1415580:LOC115479476
gene id: 1415580:LOC115479476
uniprot id: A0A6P7X5J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1415580:LOC115479948
gene id: 1415580:LOC115479948
uniprot id: A0A6P7ZC68
names: Similarity
messages: Belongs to the MDM20/NAA25 family.

1415580:DRD1
gene id: 1415580:DRD1
uniprot id: A0A6P7YYJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115466349
gene id: 1415580:LOC115466349
uniprot id: A0A6P7XLL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

1415580:S1PR2
gene id: 1415580:S1PR2
uniprot id: A0A6P7XR89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

1415580:ATIC
gene id: 1415580:ATIC
uniprot id: A0A6P7YEF2
names: Similarity
messages: Belongs to the PurH family.

1415580:LOC115468198
gene id: 1415580:LOC115468198
uniprot id: A0A6P7XY01
names: Subcellular Location Annotation
messages: Membrane

1415580:HLF
gene id: 1415580:HLF
uniprot id: A0A6P7YGX2
uniprot id: A0A6P7YHA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

1415580:VGLL4
gene id: 1415580:VGLL4
uniprot id: A0A6P7Y9A6
uniprot id: A0A6P7YFG7
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

1415580:SLC9A9
gene id: 1415580:SLC9A9
uniprot id: A0A6P7YXQ6
uniprot id: A0A6P7Z5L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Endosome membrane
messages: Membrane

1415580:KCNG3
gene id: 1415580:KCNG3
uniprot id: A0A6P7XAY9
uniprot id: A0A6P7XIH8
names: Subcellular Location Annotation
messages: Membrane

1415580:PBRM1
gene id: 1415580:PBRM1
uniprot id: A0A6P7Y7L4
uniprot id: A0A6P7Y7M0
uniprot id: A0A6P7YEQ0
uniprot id: A0A6P7YF05
uniprot id: A0A6P7YF10
uniprot id: A0A6P7YKB8
uniprot id: A0A6P7YKJ9
uniprot id: A0A6P7YKK4
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115481623
gene id: 1415580:LOC115481623
uniprot id: A0A6P7ZBS8
uniprot id: A0A6P7ZFX7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.

1415580:FH
gene id: 1415580:FH
uniprot id: A0A6P7X9H0
names: Function
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Catalyzes the hydration of fumarate to L-malate in the tricarboxylic acid (TCA) cycle to facilitate a transition step in the production of energy in the form of NADH.

1415580:GRHL3
gene id: 1415580:GRHL3
uniprot id: A0A6P7ZCM9
uniprot id: A0A6P7ZKW0
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115462204
gene id: 1415580:LOC115462204
uniprot id: A0A6P7XD39
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1415580:TMEM131L
gene id: 1415580:TMEM131L
uniprot id: A0A6P7WWB0
uniprot id: A0A6P7X298
uniprot id: A0A6P7XA86
names: Similarity
messages: Belongs to the TMEM131 family.

1415580:LOC115474547
gene id: 1415580:LOC115474547
uniprot id: A0A6P7YMB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

1415580:LOC115479103
gene id: 1415580:LOC115479103
uniprot id: A0A6P7Z038
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

1415580:LOC115457368
gene id: 1415580:LOC115457368
uniprot id: A0A6P7WWL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LGI4
gene id: 1415580:LGI4
uniprot id: A0A6P7YW68
names: Subcellular Location Annotation
messages: Secreted

1415580:ALG6
gene id: 1415580:ALG6
uniprot id: A0A6P7YCI4
uniprot id: A0A6P7YCU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol.
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:LOC115477104
gene id: 1415580:LOC115477104
uniprot id: A0A6P7Z1C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC85 family.
messages: adherens junction

1415580:GAS6
gene id: 1415580:GAS6
uniprot id: A0A6P7XXT0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:YIPF6
gene id: 1415580:YIPF6
uniprot id: A0A6P7YKK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

1415580:LOC115457861
gene id: 1415580:LOC115457861
uniprot id: A0A6P7WSM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115480390
gene id: 1415580:LOC115480390
uniprot id: A0A6P7ZEL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAUG family.
messages: Cytoplasm

1415580:PFDN1
gene id: 1415580:PFDN1
uniprot id: A0A6P7YV35
uniprot id: A0A6P7YW79
uniprot id: A0A6P7YZZ6
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

1415580:TOR4A
gene id: 1415580:TOR4A
uniprot id: A0A6P7YF22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.
messages: Membrane

1415580:DBH
gene id: 1415580:DBH
uniprot id: A0A6P7Y378
names: Similarity
messages: Belongs to the copper type II ascorbate-dependent monooxygenase family.

1415580:LOC115470192
gene id: 1415580:LOC115470192
uniprot id: A0A6P7Y8A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

1415580:LOC115470995
gene id: 1415580:LOC115470995
uniprot id: A0A6P7YBU2
names: Similarity
messages: Belongs to the cytochrome b5 family.

1415580:BSX
gene id: 1415580:BSX
uniprot id: A0A6P7ZAF3
names: Subcellular Location Annotation
messages: Nucleus

1415580:PPP2CA
gene id: 1415580:PPP2CA
uniprot id: A0A6P7YJL1
uniprot id: A0A6P7YSJ1
names: Similarity
messages: Belongs to the PPP phosphatase family.

1415580:EEF1G
gene id: 1415580:EEF1G
uniprot id: A0A6P7ZCW7
names: Function
names: Subunit
messages: EF-1 is composed of four subunits: alpha, beta, delta, and gamma.
messages: Probably plays a role in anchoring the complex to other cellular components.

1415580:CEBPZ
gene id: 1415580:CEBPZ
uniprot id: A0A6P7XEI8
names: Similarity
messages: Belongs to the CBF/MAK21 family.

1415580:LOC115474597
gene id: 1415580:LOC115474597
uniprot id: A0A6P7YRV8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Late endosome
messages: Lysosome
messages: Membrane

1415580:PLOD1
gene id: 1415580:PLOD1
uniprot id: A0A6P7WEI0
uniprot id: A0A6P7WKN4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

1415580:LOC115466744
gene id: 1415580:LOC115466744
uniprot id: A0A6P7XEV1
names: Similarity
messages: Belongs to the intermediate filament family.

1415580:LOC115470563
gene id: 1415580:LOC115470563
uniprot id: A0A6P7XW69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

1415580:CENPT
gene id: 1415580:CENPT
uniprot id: A0A6P7Y9M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-T/CNN1 family.
messages: Nucleus
messages: kinetochore

1415580:HOXD9
gene id: 1415580:HOXD9
uniprot id: A0A6P7YIA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

1415580:LOC115469642
gene id: 1415580:LOC115469642
uniprot id: A0A6P7Y5B0
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115462156
gene id: 1415580:LOC115462156
uniprot id: A0A6P7WXS6
names: Subcellular Location Annotation
messages: Nucleus

1415580:SYN3
gene id: 1415580:SYN3
uniprot id: A0A6P7Z5L7
uniprot id: A0A6P7Z6I4
names: Similarity
messages: Belongs to the synapsin family.

1415580:NDUFB10
gene id: 1415580:NDUFB10
uniprot id: A0A6P7YW53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit that is involved in the functional assembly of the mitochondrial respiratory chain complex I. Complex I has an NADH dehydrogenase activity with ubiquinone as an immediate electron acceptor and mediates the transfer of electrons from NADH to the respiratory chain.
messages: Belongs to the complex I NDUFB10 subunit family.
messages: Mitochondrion inner membrane

1415580:PSIP1
gene id: 1415580:PSIP1
uniprot id: A0A6P7X353
uniprot id: A0A6P7XBX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HDGF family.
messages: Nucleus

1415580:ATP2C1
gene id: 1415580:ATP2C1
uniprot id: A0A6P7Y3Y3
uniprot id: A0A6P7YB39
uniprot id: A0A6P7YB44
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Golgi stack membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer. Homodimer.
messages: trans-Golgi network membrane

1415580:CACNA2D4
gene id: 1415580:CACNA2D4
uniprot id: A0A6P7Z1T3
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

1415580:LOC115461170
gene id: 1415580:LOC115461170
uniprot id: A0A6P7X2G3
names: Similarity
messages: Belongs to the cytochrome P450 family.

1415580:LSM14B
gene id: 1415580:LSM14B
uniprot id: A0A6P7YRB5
uniprot id: A0A6P7YVI5
names: Similarity
messages: Belongs to the LSM14 family.

1415580:AGBL3
gene id: 1415580:AGBL3
uniprot id: A0A6P7YVM9
uniprot id: A0A6P7Z3A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

1415580:LOC115470042
gene id: 1415580:LOC115470042
uniprot id: A0A6P7Y0Y7
names: Similarity
messages: Belongs to the glycosyl hydrolase 79 family.

1415580:LOC115473782
gene id: 1415580:LOC115473782
uniprot id: A0A6P7YB69
uniprot id: A0A6P7YIK9
names: Similarity
messages: Belongs to the centrin family.

1415580:ARFGEF1
gene id: 1415580:ARFGEF1
uniprot id: A0A6P7YVG9
uniprot id: A0A6P7Z1M9
names: Subcellular Location Annotation
messages: Golgi apparatus
messages: perinuclear region

1415580:KEAP1
gene id: 1415580:KEAP1
uniprot id: A0A6P7XR62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KEAP1 family.
messages: Cytoplasm
messages: Nucleus

1415580:STAT1
gene id: 1415580:STAT1
uniprot id: A0A6P7YNF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

1415580:NTNG1
gene id: 1415580:NTNG1
uniprot id: A0A6P7YAX0
uniprot id: A0A6P7YG60
uniprot id: A0A6P7YGR6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115480049
gene id: 1415580:LOC115480049
uniprot id: A0A6P7Z4Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

1415580:NR3C1
gene id: 1415580:NR3C1
uniprot id: A0A6P7Z034
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Mitochondrion
messages: Nucleus
messages: centrosome
messages: spindle

1415580:LOC115462363
gene id: 1415580:LOC115462363
uniprot id: A0A6P7XCB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

1415580:LOC115476721
gene id: 1415580:LOC115476721
uniprot id: A0A6P7YPB7
uniprot id: A0A6P7YX70
names: Similarity
messages: Belongs to the cytochrome P450 family.

1415580:SOX10
gene id: 1415580:SOX10
uniprot id: A0A6P7YLS6
names: Subcellular Location Annotation
messages: Nucleus

1415580:NR4A3
gene id: 1415580:NR4A3
uniprot id: A0A6P7Y7Q8
uniprot id: A0A6P7YDX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

1415580:CDC42SE1
gene id: 1415580:CDC42SE1
uniprot id: A0A6P7X0X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Membrane
messages: Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly.
messages: cytoskeleton

1415580:UFD1
gene id: 1415580:UFD1
uniprot id: A0A6P7Z9Z6
names: Similarity
messages: Belongs to the UFD1 family.

1415580:HOXB6
gene id: 1415580:HOXB6
uniprot id: A0A6P7ZV70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

1415580:LOC115481146
gene id: 1415580:LOC115481146
uniprot id: A0A6P7X5J9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1415580:LOC115457197
gene id: 1415580:LOC115457197
uniprot id: A0A6P7WGV1
names: Subcellular Location Annotation
messages: Membrane

1415580:SLCO2B1
gene id: 1415580:SLCO2B1
uniprot id: A0A6P7XK67
uniprot id: A0A6P7XRZ8
uniprot id: A0A6P7XTM0
uniprot id: A0A6P7XYP3
uniprot id: A0A6P7XZC8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:LOC115478187
gene id: 1415580:LOC115478187
uniprot id: A0A6P7YW09
names: Similarity
messages: Belongs to the CDI family.

1415580:LOC115461465
gene id: 1415580:LOC115461465
uniprot id: A0A6P7X994
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1415580:MUC5AC
gene id: 1415580:MUC5AC
uniprot id: A0A6P7Y241
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:FAT3
gene id: 1415580:FAT3
uniprot id: A0A6P7XU38
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:DNAAF3
gene id: 1415580:DNAAF3
uniprot id: A0A6P7X6Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNAAF3 family.
messages: Cytoplasm
messages: Dynein axonemal particle
messages: Required for the assembly of axonemal inner and outer dynein arms. Involved in preassembly of dyneins into complexes before their transport into cilia.

1415580:MCTS1
gene id: 1415580:MCTS1
uniprot id: A0A6P7YFN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCTS1 family.
messages: Cytoplasm

1415580:LOC115482104
gene id: 1415580:LOC115482104
uniprot id: A0A6P7ZW17
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

1415580:FAM3C
gene id: 1415580:FAM3C
uniprot id: A0A6P7Z9P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

1415580:USP48
gene id: 1415580:USP48
uniprot id: A0A6P7ZL18
uniprot id: A0A6P7ZXG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Nucleus

1415580:HSPA13
gene id: 1415580:HSPA13
uniprot id: A0A6P7Y4W4
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1415580:MTMR1
gene id: 1415580:MTMR1
uniprot id: A0A6P7YNK8
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

1415580:LOC115458207
gene id: 1415580:LOC115458207
uniprot id: A0A6P7WU51
names: Subcellular Location Annotation
messages: Membrane

1415580:GTF2I
gene id: 1415580:GTF2I
uniprot id: A0A6P7WLT8
uniprot id: A0A6P7WNS0
uniprot id: A0A6P7WVT9
names: Subcellular Location Annotation
messages: Nucleus

1415580:GBA
gene id: 1415580:GBA
uniprot id: A0A6P7WHI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 30 family.
messages: Lysosome membrane

1415580:LOC115458132
gene id: 1415580:LOC115458132
uniprot id: A0A6P7X121
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115472955
gene id: 1415580:LOC115472955
uniprot id: A0A6P7Y762
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

1415580:AMDHD2
gene id: 1415580:AMDHD2
uniprot id: A0A6P7YRH1
uniprot id: A0A6P7YS77
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1415580:MRPS24
gene id: 1415580:MRPS24
uniprot id: A0A6P7XYC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Mitochondrion

1415580:LOC115480169
gene id: 1415580:LOC115480169
uniprot id: A0A6P7ZDJ2
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:SFMBT2
gene id: 1415580:SFMBT2
uniprot id: A0A6P7Z693
uniprot id: A0A6P7Z9N9
names: Subcellular Location Annotation
messages: Nucleus

1415580:RPL3L
gene id: 1415580:RPL3L
uniprot id: A0A6P7YJV0
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

1415580:MCRIP2
gene id: 1415580:MCRIP2
uniprot id: A0A6P7YL48
uniprot id: A0A6P7YU23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCRIP family.
messages: Nucleus
messages: Stress granule

1415580:SDHAF2
gene id: 1415580:SDHAF2
uniprot id: A0A6P7XVM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SDHAF2 family.
messages: Interacts with SDHA within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer.

1415580:C5H16orf87
gene id: 1415580:C5H16orf87
uniprot id: A0A6P7XXV7
uniprot id: A0A6P7Y5M4
names: Similarity
messages: Belongs to the UPF0547 family.

1415580:COMTD1
gene id: 1415580:COMTD1
uniprot id: A0A6P7Y1V5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

1415580:TMEM214
gene id: 1415580:TMEM214
uniprot id: A0A6P7XPL4
uniprot id: A0A6P7XVG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TMEM214 family.
messages: Constitutively interacts with CASP4; required for the localization of procaspase 4 to the ER.
messages: Critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. Required or the activation of CASP4 following endoplasmic reticulum stress.
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:ITGA2
gene id: 1415580:ITGA2
uniprot id: A0A6P7X0C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

1415580:CERS6
gene id: 1415580:CERS6
uniprot id: A0A6P7YKK1
uniprot id: A0A6P7YQ17
uniprot id: A0A6P7YQE5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

1415580:LOC115461096
gene id: 1415580:LOC115461096
uniprot id: A0A6P7WZH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115478978
gene id: 1415580:LOC115478978
uniprot id: A0A6P7Z7C6
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

1415580:CDH22
gene id: 1415580:CDH22
uniprot id: A0A6P7YUL6
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

1415580:NDUFS5
gene id: 1415580:NDUFS5
uniprot id: A0A6P7ZAA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS5 subunit family.
messages: Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.
messages: Membrane
messages: Mitochondrion inner membrane

1415580:PPP1R1B
gene id: 1415580:PPP1R1B
uniprot id: A0A6P7ZV32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein phosphatase inhibitor 1 family.
messages: Cytoplasm
messages: Inhibitor of protein-phosphatase 1.

1415580:PLK1
gene id: 1415580:PLK1
uniprot id: A0A6P7YWL0
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

1415580:TUBB
gene id: 1415580:TUBB
uniprot id: A0A6P7XJA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

1415580:LOC115457952
gene id: 1415580:LOC115457952
uniprot id: A0A6P7WJN4
uniprot id: A0A6P7X058
names: Similarity
messages: Belongs to the NXPE family.

1415580:CLN3
gene id: 1415580:CLN3
uniprot id: A0A6P7YF02
uniprot id: A0A6P7YLY7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the battenin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lysosome membrane
messages: Membrane

1415580:LCORL
gene id: 1415580:LCORL
uniprot id: A0A6P7X948
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115456844
gene id: 1415580:LOC115456844
uniprot id: A0A6P7WFP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

1415580:ASPHD1
gene id: 1415580:ASPHD1
uniprot id: A0A6P7YPK6
names: Similarity
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.

1415580:PARVG
gene id: 1415580:PARVG
uniprot id: A0A6P7Z6D0
uniprot id: A0A6P7Z795
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parvin family.
messages: cytoskeleton

1415580:LOC115474753
gene id: 1415580:LOC115474753
uniprot id: A0A6P7YSL8
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1415580:PAPOLG
gene id: 1415580:PAPOLG
uniprot id: A0A6P7X8X6
uniprot id: A0A6P7X8X9
uniprot id: A0A6P7XFS9
uniprot id: A0A6P7XFT3
uniprot id: A0A6P7XHX0
uniprot id: A0A6P7XHX6
uniprot id: A0A6P7XN32
uniprot id: A0A6P7XN36
uniprot id: A0A6P7XNQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Nucleus

1415580:LOC115482060
gene id: 1415580:LOC115482060
uniprot id: A0A6P7ZDP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:PROC
gene id: 1415580:PROC
uniprot id: A0A6P7Z6Z8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

1415580:LOC115473053
gene id: 1415580:LOC115473053
uniprot id: A0A6P7YKD1
names: Similarity
messages: Belongs to the cytochrome P450 family.

1415580:LOC115472690
gene id: 1415580:LOC115472690
uniprot id: A0A6P7YD96
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1415580:PCSK5
gene id: 1415580:PCSK5
uniprot id: A0A6P7X8E3
uniprot id: A0A6P7XG01
names: Similarity
messages: Belongs to the peptidase S8 family.

1415580:UROD
gene id: 1415580:UROD
uniprot id: A0A6P7Y0A8
names: Similarity
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Homodimer.

1415580:LOC115470753
gene id: 1415580:LOC115470753
uniprot id: A0A6P7YBA6
names: Subcellular Location Annotation
messages: Membrane

1415580:SNX25
gene id: 1415580:SNX25
uniprot id: A0A6P7X1X6
names: Similarity
messages: Belongs to the sorting nexin family.

1415580:TGM4
gene id: 1415580:TGM4
uniprot id: A0A6P7YPI4
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

1415580:LOC115458427
gene id: 1415580:LOC115458427
uniprot id: A0A6P7WV58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115457831
gene id: 1415580:LOC115457831
uniprot id: A0A6P7WZH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115471341
gene id: 1415580:LOC115471341
uniprot id: A0A6P7XZU6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:ZGPAT
gene id: 1415580:ZGPAT
uniprot id: A0A6P7YNK2
uniprot id: A0A6P7YWC2
names: Subcellular Location Annotation
messages: Nucleus

1415580:TXNL4B
gene id: 1415580:TXNL4B
uniprot id: A0A6P7XX53
uniprot id: A0A6P7Y511
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

1415580:LOC115456965
gene id: 1415580:LOC115456965
uniprot id: A0A6P7WIR1
names: Subcellular Location Annotation
messages: Membrane

1415580:TSC22D1
gene id: 1415580:TSC22D1
uniprot id: A0A6P7XM23
uniprot id: A0A6P7XTN9
uniprot id: A0A6P7XV55
uniprot id: A0A6P7Y059
uniprot id: A0A6P7Y0R4
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

1415580:JAG1
gene id: 1415580:JAG1
uniprot id: A0A6P7XG77
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

1415580:LOC115481388
gene id: 1415580:LOC115481388
uniprot id: A0A6P7ZAI1
names: Similarity
messages: Belongs to the intermediate filament family.

1415580:NRG1
gene id: 1415580:NRG1
uniprot id: A0A6P7X424
uniprot id: A0A6P7XAM1
uniprot id: A0A6P7XCW7
uniprot id: A0A6P7XJA1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuregulin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted

1415580:LOC115464679
gene id: 1415580:LOC115464679
uniprot id: A0A6P7XCD3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LOC115461931
gene id: 1415580:LOC115461931
uniprot id: A0A6P7WXA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:GRIK3
gene id: 1415580:GRIK3
uniprot id: A0A6P7Z959
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

1415580:POLA1
gene id: 1415580:POLA1
uniprot id: A0A6P7Y543
uniprot id: A0A6P7Y651
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

1415580:LOC115468077
gene id: 1415580:LOC115468077
uniprot id: A0A6P7XYC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

1415580:HSPD1
gene id: 1415580:HSPD1
uniprot id: A0A6P7YNN6
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.

1415580:LOC115472163
gene id: 1415580:LOC115472163
uniprot id: A0A6P7YAV5
names: Similarity
messages: Belongs to the cholesterol 7-desaturase family.

1415580:RBPJL
gene id: 1415580:RBPJL
uniprot id: A0A6P7YVF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Su(H) family.
messages: Nucleus

1415580:HOXA2
gene id: 1415580:HOXA2
uniprot id: A0A6P7Y537
names: Subcellular Location Annotation
messages: Nucleus

1415580:PLRG1
gene id: 1415580:PLRG1
uniprot id: A0A6P7XBG3
names: Similarity
messages: Belongs to the WD repeat PRL1/PRL2 family.

1415580:SLC30A8
gene id: 1415580:SLC30A8
uniprot id: A0A6P7X6H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Cell membrane
messages: Membrane
messages: secretory vesicle membrane

1415580:OSBPL3
gene id: 1415580:OSBPL3
uniprot id: A0A6P7XYG7
uniprot id: A0A6P7XZG2
names: Similarity
messages: Belongs to the OSBP family.

1415580:SUPT4H1
gene id: 1415580:SUPT4H1
uniprot id: A0A6P7WN38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT4 family.
messages: Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II.
messages: Nucleus

1415580:SH3BP5
gene id: 1415580:SH3BP5
uniprot id: A0A6P7YB52
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

1415580:LOC115476654
gene id: 1415580:LOC115476654
uniprot id: A0A6P7YNY4
uniprot id: A0A6P7YVJ5
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

1415580:LOC115464387
gene id: 1415580:LOC115464387
uniprot id: A0A6P7XDM5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LOC115475863
gene id: 1415580:LOC115475863
uniprot id: A0A6P7YWL9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:HEPH
gene id: 1415580:HEPH
uniprot id: A0A6P7YSA2
names: Similarity
messages: Belongs to the multicopper oxidase family.

1415580:RFTN1
gene id: 1415580:RFTN1
uniprot id: A0A6P7XSQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the raftlin family.
messages: Cell membrane
messages: Membrane

1415580:SGPL1
gene id: 1415580:SGPL1
uniprot id: A0A6P7Y8G4
names: Similarity
messages: Belongs to the group II decarboxylase family.

1415580:C5AR1
gene id: 1415580:C5AR1
uniprot id: A0A6P7ZG15
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:ART1
gene id: 1415580:ART1
uniprot id: A0A6P7XJM2
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

1415580:CD180
gene id: 1415580:CD180
uniprot id: A0A6P7X9A1
names: Similarity
messages: Belongs to the Toll-like receptor family.

1415580:STAG2
gene id: 1415580:STAG2
uniprot id: A0A6P7YKW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

1415580:SLC6A5
gene id: 1415580:SLC6A5
uniprot id: A0A6P7XX96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1415580:LOC115472450
gene id: 1415580:LOC115472450
uniprot id: A0A6P7YC21
names: Similarity
names: Subunit
messages: Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily.
messages: Heterodimer of a catalytic heavy chain and a regulatory light chain.

1415580:LOC115476814
gene id: 1415580:LOC115476814
uniprot id: A0A6P7Z0G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Cytoplasm
messages: Nucleus
messages: Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.

1415580:LOC115475017
gene id: 1415580:LOC115475017
uniprot id: A0A6P7YPF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:TMEM192
gene id: 1415580:TMEM192
uniprot id: A0A6P7X4Q8
uniprot id: A0A6P7XA44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM192 family.
messages: Late endosome
messages: Lysosome membrane
messages: Membrane

1415580:LOC115473512
gene id: 1415580:LOC115473512
uniprot id: A0A6P7YHH3
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

1415580:CUL4B
gene id: 1415580:CUL4B
uniprot id: A0A6P7YSZ7
names: Similarity
messages: Belongs to the cullin family.

1415580:GPR68
gene id: 1415580:GPR68
uniprot id: A0A6P7Z2T4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:LOC115467066
gene id: 1415580:LOC115467066
uniprot id: A0A6P7XVA6
names: Similarity
messages: Belongs to the cytochrome P450 family.

1415580:PROKR1
gene id: 1415580:PROKR1
uniprot id: A0A6P7X9D7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:NEK6
gene id: 1415580:NEK6
uniprot id: A0A6P7YJI5
names: Similarity
messages: Belongs to the protein kinase superfamily.

1415580:P3H1
gene id: 1415580:P3H1
uniprot id: A0A6P7WV45
names: Similarity
messages: Belongs to the leprecan family.

1415580:LOC115465268
gene id: 1415580:LOC115465268
uniprot id: A0A6P7X7I9
uniprot id: A0A6P7XE96
uniprot id: A0A6P7XLK9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

1415580:LOC115481700
gene id: 1415580:LOC115481700
uniprot id: A0A6P7ZPZ0
names: Similarity
messages: Belongs to the VPS28 family.

1415580:TWF2
gene id: 1415580:TWF2
uniprot id: A0A6P7YHC0
uniprot id: A0A6P7YN26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

1415580:EDNRA
gene id: 1415580:EDNRA
uniprot id: A0A6P7XAD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with HDAC7 and KAT5.
messages: Membrane
messages: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.

1415580:EIF4E
gene id: 1415580:EIF4E
uniprot id: A0A6P7X280
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

1415580:CDK5RAP3
gene id: 1415580:CDK5RAP3
uniprot id: A0A6P7ZCW1
uniprot id: A0A6P7ZH80
names: Similarity
messages: Belongs to the CDK5RAP3 family.

1415580:LOC115458191
gene id: 1415580:LOC115458191
uniprot id: A0A6P7WKP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115461967
gene id: 1415580:LOC115461967
uniprot id: A0A6P7X5X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115472665
gene id: 1415580:LOC115472665
uniprot id: A0A6P7YIX4
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

1415580:PRRX2
gene id: 1415580:PRRX2
uniprot id: A0A6P7YI30
names: Subcellular Location Annotation
messages: Nucleus

1415580:TEKT3
gene id: 1415580:TEKT3
uniprot id: A0A6P7YG22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

1415580:CIT
gene id: 1415580:CIT
uniprot id: A0A6P7ZA27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cytoplasm
messages: Plays a role in cytokinesis. Displays serine/threonine protein kinase activity.

1415580:TRPV4
gene id: 1415580:TRPV4
uniprot id: A0A6P7ZJN1
names: Subcellular Location Annotation
messages: Membrane

1415580:THNSL2
gene id: 1415580:THNSL2
uniprot id: A0A6P7XCT6
names: Similarity
messages: Belongs to the threonine synthase family.

1415580:LOC115462154
gene id: 1415580:LOC115462154
uniprot id: A0A6P7XBT7
names: Similarity
messages: Belongs to the UPF0598 family.

1415580:LOC115458149
gene id: 1415580:LOC115458149
uniprot id: A0A6P7WKJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:ANO1
gene id: 1415580:ANO1
uniprot id: A0A6P7Y194
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:ALDOA
gene id: 1415580:ALDOA
uniprot id: A0A6P7YPI2
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

1415580:GNG2
gene id: 1415580:GNG2
uniprot id: A0A6P7Z0M2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

1415580:RIOK2
gene id: 1415580:RIOK2
uniprot id: A0A6P7XG96
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1415580:CMC4
gene id: 1415580:CMC4
uniprot id: A0A6P7YCN7
names: Similarity
messages: Belongs to the CMC4 family.

1415580:LOC115479468
gene id: 1415580:LOC115479468
uniprot id: A0A6P7ZCZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

1415580:LOC115464966
gene id: 1415580:LOC115464966
uniprot id: A0A6P7X6I9
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

1415580:CMTM8
gene id: 1415580:CMTM8
uniprot id: A0A6P7YA95
names: Subcellular Location Annotation
messages: Membrane

1415580:SCD
gene id: 1415580:SCD
uniprot id: A0A6P7Y3F5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

1415580:PIGB
gene id: 1415580:PIGB
uniprot id: A0A6P7WV19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third alpha-1,2-mannose to Man2-GlcN-acyl-PI during GPI precursor assembly.
messages: Membrane

1415580:NAA35
gene id: 1415580:NAA35
uniprot id: A0A6P7X899
uniprot id: A0A6P7XGY5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MAK10 family.
messages: Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.
messages: Cytoplasm

1415580:TRPM3
gene id: 1415580:TRPM3
uniprot id: A0A6P7X2D1
names: Subcellular Location Annotation
messages: Membrane

1415580:RUNX3
gene id: 1415580:RUNX3
uniprot id: A0A6P7Z9C0
names: Subcellular Location Annotation
messages: Nucleus

1415580:GJB2
gene id: 1415580:GJB2
uniprot id: A0A6P7XSX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

1415580:NCSTN
gene id: 1415580:NCSTN
uniprot id: A0A6P7WJ52
uniprot id: A0A6P7WSH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicastrin family.
messages: Membrane

1415580:LOC115472379
gene id: 1415580:LOC115472379
uniprot id: A0A6P7Y4N0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1415580:STT3A
gene id: 1415580:STT3A
uniprot id: A0A6P7ZU64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

1415580:ANO10
gene id: 1415580:ANO10
uniprot id: A0A6P7YGH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

1415580:DAP3
gene id: 1415580:DAP3
uniprot id: A0A6P7WG59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS29 family.
messages: Mitochondrion

1415580:SLC25A48
gene id: 1415580:SLC25A48
uniprot id: A0A6P7YN56
uniprot id: A0A6P7YVU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1415580:IZUMO3
gene id: 1415580:IZUMO3
uniprot id: A0A6P7XKJ4
names: Similarity
messages: Belongs to the Izumo family.

1415580:LOC115472943
gene id: 1415580:LOC115472943
uniprot id: A0A6P7YEH5
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

1415580:KCNJ16
gene id: 1415580:KCNJ16
uniprot id: A0A6P7YMX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

1415580:LOC115462775
gene id: 1415580:LOC115462775
uniprot id: A0A6P7X5P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:PKP3
gene id: 1415580:PKP3
uniprot id: A0A6P7XNX7
uniprot id: A0A6P7Y1Z8
names: Similarity
messages: Belongs to the beta-catenin family.

1415580:ATP2A1
gene id: 1415580:ATP2A1
uniprot id: A0A6P7YND1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

1415580:CLEC14A
gene id: 1415580:CLEC14A
uniprot id: A0A6P7Z625
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:EIF4EBP1
gene id: 1415580:EIF4EBP1
uniprot id: A0A6P7Y422
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

1415580:SLC2A2
gene id: 1415580:SLC2A2
uniprot id: A0A6P7ZBK7
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

1415580:RNF7
gene id: 1415580:RNF7
uniprot id: A0A6P7Z8G6
names: Similarity
messages: Belongs to the RING-box family.

1415580:LEPR
gene id: 1415580:LEPR
uniprot id: A0A6P7YEZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

1415580:LOC115476954
gene id: 1415580:LOC115476954
uniprot id: A0A6P7YWS5
uniprot id: A0A6P7Z0X6
uniprot id: A0A6P7Z0Y1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1415580:LOC115461950
gene id: 1415580:LOC115461950
uniprot id: A0A6P7X3A2
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115461939
gene id: 1415580:LOC115461939
uniprot id: A0A6P7XBB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:FAM83E
gene id: 1415580:FAM83E
uniprot id: A0A6P7XSI5
names: Similarity
messages: Belongs to the FAM83 family.

1415580:COQ9
gene id: 1415580:COQ9
uniprot id: A0A6P7XVG2
uniprot id: A0A6P7Y2Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ9 family.
messages: Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
messages: Mitochondrion

1415580:LOC115475102
gene id: 1415580:LOC115475102
uniprot id: A0A6P7YGY4
names: Similarity
messages: Belongs to the helicase family.

1415580:MAEL
gene id: 1415580:MAEL
uniprot id: A0A6P7YD30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the maelstrom family.
messages: Nucleus
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for the localization of germ-cell factors to the meiotic nuage.

1415580:GAL
gene id: 1415580:GAL
uniprot id: A0A6P7XQK4
uniprot id: A0A6P7XSA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galanin family.
messages: Secreted

1415580:LOC115478008
gene id: 1415580:LOC115478008
uniprot id: A0A6P7YV75
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

1415580:LOC115476266
gene id: 1415580:LOC115476266
uniprot id: A0A6P7YUT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAIF1 family.
messages: Induces apoptosis.
messages: Nucleus

1415580:LDLRAD1
gene id: 1415580:LDLRAD1
uniprot id: A0A6P7Y9V5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:KIF22
gene id: 1415580:KIF22
uniprot id: A0A6P7YNW0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

1415580:DNAH8
gene id: 1415580:DNAH8
uniprot id: A0A6P7XWP1
names: Similarity
messages: Belongs to the dynein heavy chain family.

1415580:EEF2KMT
gene id: 1415580:EEF2KMT
uniprot id: A0A6P7YQD7
uniprot id: A0A6P7Z131
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EEF2KMT family.

1415580:LOC115466584
gene id: 1415580:LOC115466584
uniprot id: A0A6P7XE17
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115482645
gene id: 1415580:LOC115482645
uniprot id: A0A6P7ZXA1
names: Subcellular Location Annotation
messages: perinuclear region

1415580:MAP4K5
gene id: 1415580:MAP4K5
uniprot id: A0A6P7YYB6
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

1415580:CREB3L2
gene id: 1415580:CREB3L2
uniprot id: A0A6P7YXD0
uniprot id: A0A6P7Z577
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family. ATF subfamily.
messages: Binds DNA as a dimer.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

1415580:LOC115457262
gene id: 1415580:LOC115457262
uniprot id: A0A6P7WWB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:GATM
gene id: 1415580:GATM
uniprot id: A0A6P7WQI5
uniprot id: A0A6P7WZ07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the amidinotransferase family.
messages: Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine.
messages: Homodimer.
messages: Mitochondrion inner membrane

1415580:AFAP1L1
gene id: 1415580:AFAP1L1
uniprot id: A0A6P7YJN0
uniprot id: A0A6P7YSL1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in podosome and invadosome formation.
messages: invadopodium
messages: podosome

1415580:LOC115464967
gene id: 1415580:LOC115464967
uniprot id: A0A6P7XFG8
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

1415580:CSNK1G2
gene id: 1415580:CSNK1G2
uniprot id: A0A6P7Z7V6
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

1415580:LOC115457267
gene id: 1415580:LOC115457267
uniprot id: A0A6P7WWB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:KDM5A
gene id: 1415580:KDM5A
uniprot id: A0A6P7YSG5
uniprot id: A0A6P7Z036
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

1415580:LOC115463478
gene id: 1415580:LOC115463478
uniprot id: A0A6P7X989
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:NTRK1
gene id: 1415580:NTRK1
uniprot id: A0A6P7WSC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane
messages: Membrane

1415580:PPP2R2A
gene id: 1415580:PPP2R2A
uniprot id: A0A6P7XQM7
uniprot id: A0A6P7XYN5
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

1415580:IL6ST
gene id: 1415580:IL6ST
uniprot id: A0A6P7XEE3
uniprot id: A0A6P7XFJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

1415580:LOC115472486
gene id: 1415580:LOC115472486
uniprot id: A0A6P7Y536
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

1415580:LOC115464578
gene id: 1415580:LOC115464578
uniprot id: A0A6P7X5C5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LOC115482396
gene id: 1415580:LOC115482396
uniprot id: A0A6P7ZL72
names: Subcellular Location Annotation
messages: Nucleus

1415580:SLC39A5
gene id: 1415580:SLC39A5
uniprot id: A0A6P7X673
uniprot id: A0A6P7XCZ0
uniprot id: A0A6P7XF46
names: Subcellular Location Annotation
messages: Membrane

1415580:RBCK1
gene id: 1415580:RBCK1
uniprot id: A0A6P7YUT7
names: Similarity
messages: Belongs to the RBR family.

1415580:SPAM1
gene id: 1415580:SPAM1
uniprot id: A0A6P7Z7K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 56 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115467264
gene id: 1415580:LOC115467264
uniprot id: A0A6P7XW63
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:ALG12
gene id: 1415580:ALG12
uniprot id: A0A6P7YWW3
uniprot id: A0A6P7Z2N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation.
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:LOC115476020
gene id: 1415580:LOC115476020
uniprot id: A0A6P7YX43
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

1415580:NPR2
gene id: 1415580:NPR2
uniprot id: A0A6P7WZF4
uniprot id: A0A6P7X866
uniprot id: A0A6P7XEP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

1415580:AFG3L2
gene id: 1415580:AFG3L2
uniprot id: A0A6P7YTB4
uniprot id: A0A6P7YU78
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

1415580:LOC115477622
gene id: 1415580:LOC115477622
uniprot id: A0A6P7Z423
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Secreted

1415580:MINAR2
gene id: 1415580:MINAR2
uniprot id: A0A6P7XB82
names: Similarity
messages: Belongs to the MINAR family.

1415580:LHX6
gene id: 1415580:LHX6
uniprot id: A0A6P7YB30
names: Subcellular Location Annotation
messages: Nucleus

1415580:ANAPC15
gene id: 1415580:ANAPC15
uniprot id: A0A6P7XAS3
uniprot id: A0A6P7XHI1
names: Similarity
messages: Belongs to the APC15 family.

1415580:POLB
gene id: 1415580:POLB
uniprot id: A0A6P7Y5A5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Cytoplasm
messages: DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

1415580:LOC115474518
gene id: 1415580:LOC115474518
uniprot id: A0A6P7YLI6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Cytoplasm
messages: Homodimer.

1415580:GATA6
gene id: 1415580:GATA6
uniprot id: A0A6P7YPZ0
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115478811
gene id: 1415580:LOC115478811
uniprot id: A0A6P7Z9B1
names: Similarity
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.

1415580:PRKCE
gene id: 1415580:PRKCE
uniprot id: A0A6P7XMP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

1415580:HSPA14
gene id: 1415580:HSPA14
uniprot id: A0A6P7Z9Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: cytosol

1415580:C4H11orf49
gene id: 1415580:C4H11orf49
uniprot id: A0A6P7XIN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSTPP1 family.
messages: centriolar satellite

1415580:LOC115457135
gene id: 1415580:LOC115457135
uniprot id: A0A6P7WWW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115472039
gene id: 1415580:LOC115472039
uniprot id: A0A6P7YGE3
names: Subcellular Location Annotation
messages: Nucleus

1415580:MYO10
gene id: 1415580:MYO10
uniprot id: A0A6P7Y6L1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

1415580:SERPINH1
gene id: 1415580:SERPINH1
uniprot id: A0A6P7XYS8
names: Function
names: Similarity
messages: Belongs to the serpin family.
messages: Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.

1415580:LOC115482274
gene id: 1415580:LOC115482274
uniprot id: A0A6P7ZUY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Cell membrane
messages: Enhances Ca(2+)-mediated inhibition of inositol 1,4,5-triphosphate receptor (ITPR) Ca(2+) release.
messages: Membrane
messages: Nucleus outer membrane

1415580:LOC115482250
gene id: 1415580:LOC115482250
uniprot id: A0A6P7ZUV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gastrin/cholecystokinin family.
messages: Secreted

1415580:ADIPOR1
gene id: 1415580:ADIPOR1
uniprot id: A0A6P7ZTG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

1415580:LOC115460805
gene id: 1415580:LOC115460805
uniprot id: A0A6P7X1L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:CSTF1
gene id: 1415580:CSTF1
uniprot id: A0A6P7YVS8
names: Subcellular Location Annotation
messages: Nucleus

1415580:STK11
gene id: 1415580:STK11
uniprot id: A0A6P7ZFQ6
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. LKB1 subfamily.

1415580:KDELR1
gene id: 1415580:KDELR1
uniprot id: A0A6P7XMB9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:ST6GALNAC4
gene id: 1415580:ST6GALNAC4
uniprot id: A0A6P7YGC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

1415580:SRP9
gene id: 1415580:SRP9
uniprot id: A0A6P7XJI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP9 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm

1415580:SUMO1
gene id: 1415580:SUMO1
uniprot id: A0A6P7YLD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

1415580:CXXC1
gene id: 1415580:CXXC1
uniprot id: A0A6P7X2I4
uniprot id: A0A6P7XB90
uniprot id: A0A6P7XGJ0
names: Subcellular Location Annotation
messages: Nucleus

1415580:CMTM4
gene id: 1415580:CMTM4
uniprot id: A0A6P7XY66
names: Subcellular Location Annotation
messages: Membrane

1415580:TRAM2
gene id: 1415580:TRAM2
uniprot id: A0A6P7XG40
uniprot id: A0A6P7XM56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

1415580:THYN1
gene id: 1415580:THYN1
uniprot id: A0A6P7ZMQ5
uniprot id: A0A6P7ZVX3
uniprot id: A0A6P7ZZT1
names: Function
messages: Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

1415580:LOC115469710
gene id: 1415580:LOC115469710
uniprot id: A0A6P7XZN4
names: Similarity
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.

1415580:ELF1
gene id: 1415580:ELF1
uniprot id: A0A6P7Y082
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

1415580:HOOK3
gene id: 1415580:HOOK3
uniprot id: A0A6P7XCU2
uniprot id: A0A6P7XJ81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hook family.
messages: cytoskeleton

1415580:EFNA3
gene id: 1415580:EFNA3
uniprot id: A0A6P7WRI4
uniprot id: A0A6P7WZU2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:PRDM9
gene id: 1415580:PRDM9
uniprot id: A0A6P7Z186
names: Subcellular Location Annotation
messages: Nucleus

1415580:USP28
gene id: 1415580:USP28
uniprot id: A0A6P7ZF69
uniprot id: A0A6P7ZQV6
names: Similarity
messages: Belongs to the peptidase C19 family.

1415580:LOC115477581
gene id: 1415580:LOC115477581
uniprot id: A0A6P7Z3W3
uniprot id: A0A6P7Z4J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1415580:LOC115461352
gene id: 1415580:LOC115461352
uniprot id: A0A6P7X8T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115482242
gene id: 1415580:LOC115482242
uniprot id: A0A6P7ZUW6
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

1415580:LOC115457707
gene id: 1415580:LOC115457707
uniprot id: A0A6P7WYX3
names: Subcellular Location Annotation
messages: Membrane

1415580:TNMD
gene id: 1415580:TNMD
uniprot id: A0A6P7YHS4
names: Similarity
messages: Belongs to the chondromodulin-1 family.

1415580:EIF3B
gene id: 1415580:EIF3B
uniprot id: A0A6P7YHQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit B family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

1415580:HTR2B
gene id: 1415580:HTR2B
uniprot id: A0A6P7Z2S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: synaptosome

1415580:GNB5
gene id: 1415580:GNB5
uniprot id: A0A6P7WVJ9
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

1415580:RDH10
gene id: 1415580:RDH10
uniprot id: A0A6P7YWD0
uniprot id: A0A6P7Z2B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

1415580:PLPP4
gene id: 1415580:PLPP4
uniprot id: A0A6P7Y6J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

1415580:ABHD16A
gene id: 1415580:ABHD16A
uniprot id: A0A6P7XCK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. ABHD16 family.
messages: Membrane

1415580:LOC115480849
gene id: 1415580:LOC115480849
uniprot id: A0A6P7Z8G2
uniprot id: A0A6P7ZNM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

1415580:LOC115471384
gene id: 1415580:LOC115471384
uniprot id: A0A6P7YDR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

1415580:ANXA5
gene id: 1415580:ANXA5
uniprot id: A0A6P7X2N1
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

1415580:MC2R
gene id: 1415580:MC2R
uniprot id: A0A6P7WXT5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MRAP; increasing ligand-sensitivity and generation of cAMP. Interacts with MRAP2; competing with MRAP for binding to MC2R and impairing the binding of corticotropin (ACTH).
messages: Membrane

1415580:MTFR1
gene id: 1415580:MTFR1
uniprot id: A0A6P7Z142
uniprot id: A0A6P7Z6C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

1415580:EEF1D
gene id: 1415580:EEF1D
uniprot id: A0A6P7Z8T7
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.

1415580:LOC115463419
gene id: 1415580:LOC115463419
uniprot id: A0A6P7XB64
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

1415580:JAKMIP2
gene id: 1415580:JAKMIP2
uniprot id: A0A6P7YX68
names: Similarity
messages: Belongs to the JAKMIP family.

1415580:DTNBP1
gene id: 1415580:DTNBP1
uniprot id: A0A6P7YQV0
uniprot id: A0A6P7YV06
names: Similarity
messages: Belongs to the dysbindin family.

1415580:MOV10
gene id: 1415580:MOV10
uniprot id: A0A6P7ZW00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
messages: P-body

1415580:PTPN3
gene id: 1415580:PTPN3
uniprot id: A0A6P7Y6C3
uniprot id: A0A6P7YBW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

1415580:ASIC5
gene id: 1415580:ASIC5
uniprot id: A0A6P7XBX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Membrane

1415580:PAPOLA
gene id: 1415580:PAPOLA
uniprot id: A0A6P7YV96
uniprot id: A0A6P7Z307
uniprot id: A0A6P7Z5U2
uniprot id: A0A6P7Z6P9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Binds 2 magnesium ions. Also active with manganese.
messages: Nucleus
messages: Polymerase that creates the 3'-poly(A) tail of mRNA's.

1415580:FNTA
gene id: 1415580:FNTA
uniprot id: A0A6P7X459
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

1415580:MCTP1
gene id: 1415580:MCTP1
uniprot id: A0A6P7X141
uniprot id: A0A6P7X7I0
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115457406
gene id: 1415580:LOC115457406
uniprot id: A0A6P7WQN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115462215
gene id: 1415580:LOC115462215
uniprot id: A0A6P7X3X9
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1415580:LOC115469590
gene id: 1415580:LOC115469590
uniprot id: A0A6P7Y664
names: Similarity
messages: Belongs to the peptidase M10A family.

1415580:LOC115471609
gene id: 1415580:LOC115471609
uniprot id: A0A6P7Y0W1
uniprot id: A0A6P7Y895
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S9C family.
messages: Cytoplasm
messages: Homotetramer.

1415580:LOC115471149
gene id: 1415580:LOC115471149
uniprot id: A0A6P7Y6U4
uniprot id: A0A6P7YCZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Cell membrane
messages: Membrane
messages: Mitochondrion membrane

1415580:DDX47
gene id: 1415580:DDX47
uniprot id: A0A6P7XU07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.
messages: Cytoplasm

1415580:KCNJ11
gene id: 1415580:KCNJ11
uniprot id: A0A6P7Y264
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ11 subfamily.
messages: Membrane

1415580:CFTR
gene id: 1415580:CFTR
uniprot id: A0A6P7Z9B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the ABC transporter superfamily. ABCC family. CFTR transporter (TC 3.A.1.202) subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
messages: Recycling endosome membrane

1415580:LOC115480952
gene id: 1415580:LOC115480952
uniprot id: A0A6P7ZI81
names: Similarity
messages: Belongs to the ANP32 family.

1415580:LOC115457203
gene id: 1415580:LOC115457203
uniprot id: A0A6P7WGV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:PTH2R
gene id: 1415580:PTH2R
uniprot id: A0A6P7YPN4
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115457283
gene id: 1415580:LOC115457283
uniprot id: A0A6P7WNC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:PRICKLE1
gene id: 1415580:PRICKLE1
uniprot id: A0A6P7Z413
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prickle / espinas / testin family.
messages: Cell membrane
messages: Membrane

1415580:NPY2R
gene id: 1415580:NPY2R
uniprot id: A0A6P7WZ68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:ST8SIA6
gene id: 1415580:ST8SIA6
uniprot id: A0A6P7WRH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

1415580:LOC115482377
gene id: 1415580:LOC115482377
uniprot id: A0A6P7ZVX1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P2X receptor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

1415580:LOC115469709
gene id: 1415580:LOC115469709
uniprot id: A0A6P7Y5H5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115457433
gene id: 1415580:LOC115457433
uniprot id: A0A6P7WHF8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LOC115480023
gene id: 1415580:LOC115480023
uniprot id: A0A6P7ZCP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tim44 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion inner membrane

1415580:GCNT3
gene id: 1415580:GCNT3
uniprot id: A0A6P7X7T0
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

1415580:GDF1
gene id: 1415580:GDF1
uniprot id: A0A6P7ZGH5
names: Similarity
messages: Belongs to the TGF-beta family.

1415580:ATP8B2
gene id: 1415580:ATP8B2
uniprot id: A0A6P7WYX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

1415580:LOC115474437
gene id: 1415580:LOC115474437
uniprot id: A0A6P7YLG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

1415580:HNRNPUL2
gene id: 1415580:HNRNPUL2
uniprot id: A0A6P7ZE34
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115457219
gene id: 1415580:LOC115457219
uniprot id: A0A6P7WW71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:ATP6V0A2
gene id: 1415580:ATP6V0A2
uniprot id: A0A6P7ZDQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

1415580:LOC115462749
gene id: 1415580:LOC115462749
uniprot id: A0A6P7X5K9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:MLH3
gene id: 1415580:MLH3
uniprot id: A0A6P7Z1Y2
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

1415580:LOC115479167
gene id: 1415580:LOC115479167
uniprot id: A0A6P7Z0H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

1415580:LAMA3
gene id: 1415580:LAMA3
uniprot id: A0A6P7WUB4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

1415580:ACOX2
gene id: 1415580:ACOX2
uniprot id: A0A6P7YBU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

1415580:PCNX4
gene id: 1415580:PCNX4
uniprot id: A0A6P7YQV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

1415580:PRPF38A
gene id: 1415580:PRPF38A
uniprot id: A0A6P7Y4A3
uniprot id: A0A6P7YBC6
uniprot id: A0A6P7YHI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRP38 family.
messages: Component of the spliceosome B complex.
messages: Involved in pre-mRNA splicing as a component of the spliceosome.
messages: May be required for pre-mRNA splicing.
messages: Nucleus

1415580:ERGIC3
gene id: 1415580:ERGIC3
uniprot id: A0A6P7WXD2
uniprot id: A0A6P7YR90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

1415580:LOC115457404
gene id: 1415580:LOC115457404
uniprot id: A0A6P7WHD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:RXFP1
gene id: 1415580:RXFP1
uniprot id: A0A6P7XD49
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:LOC115478435
gene id: 1415580:LOC115478435
uniprot id: A0A6P7Z4S1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG10 glucosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:PTPA
gene id: 1415580:PTPA
uniprot id: A0A6P7YF97
uniprot id: A0A6P7YL32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1415580:IPPK
gene id: 1415580:IPPK
uniprot id: A0A6P7YDF9
names: Domain
names: Function
names: Similarity
messages: Belongs to the IPK1 type 2 family.
messages: Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
messages: The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.

1415580:HSP90AB1
gene id: 1415580:HSP90AB1
uniprot id: A0A6P7XGL0
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1415580:DPP7
gene id: 1415580:DPP7
uniprot id: A0A6P7Y5W4
names: Similarity
messages: Belongs to the peptidase S28 family.

1415580:IRX2
gene id: 1415580:IRX2
uniprot id: A0A6P7YLH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

1415580:GADD45GIP1
gene id: 1415580:GADD45GIP1
uniprot id: A0A6P7XBA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.
messages: Belongs to the mitochondrion-specific ribosomal protein mL64 family.
messages: Mitochondrion
messages: Nucleus

1415580:NDUFAF2
gene id: 1415580:NDUFAF2
uniprot id: A0A6P7X487
names: Similarity
messages: Belongs to the complex I NDUFA12 subunit family.

1415580:GALNT9
gene id: 1415580:GALNT9
uniprot id: A0A6P7ZFN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

1415580:LOC115457290
gene id: 1415580:LOC115457290
uniprot id: A0A6P7WXC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:CPD
gene id: 1415580:CPD
uniprot id: A0A6P7WUL7
names: Similarity
messages: Belongs to the peptidase M14 family.

1415580:MMP9
gene id: 1415580:MMP9
uniprot id: A0A6P7YSG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: extracellular matrix

1415580:CLRN1
gene id: 1415580:CLRN1
uniprot id: A0A6P7ZA68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

1415580:LOC115477057
gene id: 1415580:LOC115477057
uniprot id: A0A6P7YQJ2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:SLC5A11
gene id: 1415580:SLC5A11
uniprot id: A0A6P7YW49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1415580:TULP3
gene id: 1415580:TULP3
uniprot id: A0A6P7Z3C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUB family.
messages: Secreted

1415580:MUC2
gene id: 1415580:MUC2
uniprot id: A0A6P7Y6E5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:TUFM
gene id: 1415580:TUFM
uniprot id: A0A6P7YKF5
uniprot id: A0A6P7YPX6
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1415580:ATG2B
gene id: 1415580:ATG2B
uniprot id: A0A6P7YZ64
uniprot id: A0A6P7Z3A0
uniprot id: A0A6P7Z426
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG2 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Preautophagosomal structure membrane

1415580:FRZB
gene id: 1415580:FRZB
uniprot id: A0A6P7YCX3
uniprot id: A0A6P7YK33
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development.

1415580:AVPR1A
gene id: 1415580:AVPR1A
uniprot id: A0A6P7Z4L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

1415580:OIP5
gene id: 1415580:OIP5
uniprot id: A0A6P7Z365
names: Function
names: Subcellular Location Annotation
messages: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
messages: centromere

1415580:LOC115461293
gene id: 1415580:LOC115461293
uniprot id: A0A6P7X0I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FLNA (via filamin repeat 21); increases PKA-mediated phosphorylation of FLNA.
messages: Membrane
messages: This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.

1415580:CPOX
gene id: 1415580:CPOX
uniprot id: A0A6P7YB57
names: Similarity
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Homodimer.

1415580:LOC115471995
gene id: 1415580:LOC115471995
uniprot id: A0A6P7YAA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

1415580:ARL5C
gene id: 1415580:ARL5C
uniprot id: A0A6P7ZFZ8
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

1415580:FOXA1
gene id: 1415580:FOXA1
uniprot id: A0A6P7YUM7
names: Subcellular Location Annotation
messages: Nucleus

1415580:JPT2
gene id: 1415580:JPT2
uniprot id: A0A6P7Z1M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

1415580:GRM8
gene id: 1415580:GRM8
uniprot id: A0A6P7Z7U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

1415580:FOXD3
gene id: 1415580:FOXD3
uniprot id: A0A6P7YBC1
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115464431
gene id: 1415580:LOC115464431
uniprot id: A0A6P7X4Y9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LOC115464456
gene id: 1415580:LOC115464456
uniprot id: A0A6P7XBM5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:TMPO
gene id: 1415580:TMPO
uniprot id: A0A6P7Z4Z3
names: Similarity
messages: Belongs to the LEM family.

1415580:LOC115478588
gene id: 1415580:LOC115478588
uniprot id: A0A6P7Z5L4
uniprot id: A0A6P7Z925
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115466298
gene id: 1415580:LOC115466298
uniprot id: A0A6P7XLD6
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

1415580:IRF2BP1
gene id: 1415580:IRF2BP1
uniprot id: A0A6P7Z6M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF2BP family.
messages: Nucleus

1415580:CCSER2
gene id: 1415580:CCSER2
uniprot id: A0A6P7Y8V1
names: Similarity
messages: Belongs to the CCSER family.

1415580:MVP
gene id: 1415580:MVP
uniprot id: A0A6P7YIL3
names: Subcellular Location Annotation
messages: Cytoplasm

1415580:LOC115457377
gene id: 1415580:LOC115457377
uniprot id: A0A6P7WNL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:ATAT1
gene id: 1415580:ATAT1
uniprot id: A0A6P7XFE9
uniprot id: A0A6P7XKM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase ATAT1 family.
messages: Cytoplasm
messages: Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. May be involved in neuron development.
messages: axon
messages: clathrin-coated pit
messages: cytoskeleton
messages: focal adhesion
messages: spindle

1415580:SYNDIG1
gene id: 1415580:SYNDIG1
uniprot id: A0A6P7XI48
names: Similarity
messages: Belongs to the CD225/Dispanin family.

1415580:RIPOR1
gene id: 1415580:RIPOR1
uniprot id: A0A6P7Y8T5
names: Similarity
messages: Belongs to the RIPOR family.

1415580:LPCAT3
gene id: 1415580:LPCAT3
uniprot id: A0A6P7WXD7
names: Subcellular Location Annotation
messages: Membrane

1415580:TMEM255B
gene id: 1415580:TMEM255B
uniprot id: A0A6P7XIW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM255 family.
messages: Membrane

1415580:RNF40
gene id: 1415580:RNF40
uniprot id: A0A6P7YJI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRE1 family.
messages: Nucleus

1415580:ZC2HC1C
gene id: 1415580:ZC2HC1C
uniprot id: A0A6P7Z664
names: Similarity
messages: Belongs to the ZC2HC1 family.

1415580:ECSIT
gene id: 1415580:ECSIT
uniprot id: A0A6P7XB84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ECSIT family.
messages: Cytoplasm
messages: Mitochondrion
messages: Nucleus

1415580:HNRNPU
gene id: 1415580:HNRNPU
uniprot id: A0A6P7X9Q3
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115465775
gene id: 1415580:LOC115465775
uniprot id: A0A6P7XGP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

1415580:LOC115466655
gene id: 1415580:LOC115466655
uniprot id: A0A6P7XU14
names: Similarity
messages: Belongs to the nanos family.

1415580:LOC115464563
gene id: 1415580:LOC115464563
uniprot id: A0A6P7XJH7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:UBR3
gene id: 1415580:UBR3
uniprot id: A0A6P7YTW4
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

1415580:PLAC8L1
gene id: 1415580:PLAC8L1
uniprot id: A0A6P7Z1G1
names: Similarity
messages: Belongs to the cornifelin family.

1415580:CDCA2
gene id: 1415580:CDCA2
uniprot id: A0A6P7Y3S4
names: Subcellular Location Annotation
messages: Nucleus

1415580:SPOCK1
gene id: 1415580:SPOCK1
uniprot id: A0A6P7YV84
uniprot id: A0A6P7YZ35
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115463218
gene id: 1415580:LOC115463218
uniprot id: A0A6P7XFF7
names: Subcellular Location Annotation
messages: Peroxisome

1415580:UBE2E3
gene id: 1415580:UBE2E3
uniprot id: A0A6P7YKL2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

1415580:TSHZ1
gene id: 1415580:TSHZ1
uniprot id: A0A6P7YW71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.
messages: Nucleus

1415580:TDP1
gene id: 1415580:TDP1
uniprot id: A0A6P7Z6S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosyl-DNA phosphodiesterase family.
messages: Nucleus

1415580:BCAN
gene id: 1415580:BCAN
uniprot id: A0A6P7WKB7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:VPS13B
gene id: 1415580:VPS13B
uniprot id: A0A6P7ZCI7
names: Similarity
messages: Belongs to the VPS13 family.

1415580:MRGBP
gene id: 1415580:MRGBP
uniprot id: A0A6P7YZM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EAF7 family.
messages: Nucleus

1415580:RPE
gene id: 1415580:RPE
uniprot id: A0A6P7YP34
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

1415580:DVL1
gene id: 1415580:DVL1
uniprot id: A0A6P7ZFJ9
uniprot id: A0A6P7ZLV8
uniprot id: A0A6P7ZW48
names: Similarity
messages: Belongs to the DSH family.

1415580:LOC115456823
gene id: 1415580:LOC115456823
uniprot id: A0A6P7WLS6
uniprot id: A0A6P7WUR4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADPH--cytochrome P450 reductase family.
messages: Binds 1 FAD per monomer.
messages: Binds 1 FMN per monomer.
messages: Endoplasmic reticulum membrane
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5.

1415580:IFT122
gene id: 1415580:IFT122
uniprot id: A0A6P7YC05
uniprot id: A0A6P7YHD6
uniprot id: A0A6P7YHS3
names: Subcellular Location Annotation
messages: cilium

1415580:FKTN
gene id: 1415580:FKTN
uniprot id: A0A6P7XCD0
names: Similarity
messages: Belongs to the LicD transferase family.

1415580:MRM2
gene id: 1415580:MRM2
uniprot id: A0A6P7YT95
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.

1415580:LOC115470438
gene id: 1415580:LOC115470438
uniprot id: A0A6P7Y3P6
uniprot id: A0A6P7Y8Q9
uniprot id: A0A6P7Y9I2
names: Caution
names: Similarity
messages: Belongs to the CRISP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115464675
gene id: 1415580:LOC115464675
uniprot id: A0A6P7XCC7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:MMP2
gene id: 1415580:MMP2
uniprot id: A0A6P7Y5F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: extracellular matrix

1415580:ADGRF3
gene id: 1415580:ADGRF3
uniprot id: A0A6P7XK42
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115474059
gene id: 1415580:LOC115474059
uniprot id: A0A6P7YJS2
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

1415580:IFRD2
gene id: 1415580:IFRD2
uniprot id: A0A6P7Y487
uniprot id: A0A6P7YBA9
names: Similarity
messages: Belongs to the IFRD family.

1415580:LOC115464769
gene id: 1415580:LOC115464769
uniprot id: A0A6P7XER7
names: Similarity
messages: Belongs to the GAREM family.

1415580:LOC115480917
gene id: 1415580:LOC115480917
uniprot id: A0A6P7Z8T2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

1415580:EIF5A2
gene id: 1415580:EIF5A2
uniprot id: A0A6P7Z6S0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.
messages: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Critical for the efficient synthesis of peptide bonds between consecutive proline residues. Can resolve ribosomal stalling caused by consecutive prolines during translation. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis.

1415580:LOC115480123
gene id: 1415580:LOC115480123
uniprot id: A0A6P7Z559
names: Similarity
messages: Belongs to the cytochrome P450 family.

1415580:LOC115480167
gene id: 1415580:LOC115480167
uniprot id: A0A6P7Z5C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

1415580:LOC115480968
gene id: 1415580:LOC115480968
uniprot id: A0A6P7ZDI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1415580:CD5
gene id: 1415580:CD5
uniprot id: A0A6P7ZYD9
uniprot id: A0A6P7ZYG5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115457718
gene id: 1415580:LOC115457718
uniprot id: A0A6P7WPW4
names: Similarity
messages: Belongs to the TPRG1 family.

1415580:LOC115482073
gene id: 1415580:LOC115482073
uniprot id: A0A6P7ZDR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

1415580:CENPN
gene id: 1415580:CENPN
uniprot id: A0A6P7YBE2
names: Similarity
messages: Belongs to the CENP-N/CHL4 family.

1415580:LOC115461744
gene id: 1415580:LOC115461744
uniprot id: A0A6P7WWR9
uniprot id: A0A6P7X583
uniprot id: A0A6P7XAP4
uniprot id: A0A6P7XBW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm

1415580:POLR2I
gene id: 1415580:POLR2I
uniprot id: A0A6P7YK60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

1415580:GNB2
gene id: 1415580:GNB2
uniprot id: A0A6P7X1J6
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

1415580:GMPPB
gene id: 1415580:GMPPB
uniprot id: A0A6P7Y0U4
uniprot id: A0A6P7Y886
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1415580:PUS3
gene id: 1415580:PUS3
uniprot id: A0A6P7YIQ5
uniprot id: A0A6P7YJ04
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

1415580:SLC9A3
gene id: 1415580:SLC9A3
uniprot id: A0A6P7YKR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Membrane

1415580:GNG10
gene id: 1415580:GNG10
uniprot id: A0A6P7X228
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

1415580:MAT1A
gene id: 1415580:MAT1A
uniprot id: A0A6P7Y7M4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

1415580:CPSF4L
gene id: 1415580:CPSF4L
uniprot id: A0A6P7Y4H9
uniprot id: A0A6P7YBX9
uniprot id: A0A6P7YHA9
uniprot id: A0A6P7YHP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex.
messages: Nucleus

1415580:LRRC8D
gene id: 1415580:LRRC8D
uniprot id: A0A6P7YGR3
uniprot id: A0A6P7YH56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

1415580:ERAL1
gene id: 1415580:ERAL1
uniprot id: A0A6P7ZMD0
uniprot id: A0A6P7ZW99
uniprot id: A0A6P7ZZ97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly.

1415580:LOC115458432
gene id: 1415580:LOC115458432
uniprot id: A0A6P7WV65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115482225
gene id: 1415580:LOC115482225
uniprot id: A0A6P7ZJU2
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

1415580:RRM1
gene id: 1415580:RRM1
uniprot id: A0A6P7XZ00
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1415580:SPTBN1
gene id: 1415580:SPTBN1
uniprot id: A0A6P7X811
uniprot id: A0A6P7XGW5
names: Similarity
messages: Belongs to the spectrin family.

1415580:LOC115466135
gene id: 1415580:LOC115466135
uniprot id: A0A6P7XIK9
uniprot id: A0A6P7XQV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR5 subfamily.
messages: Nucleus

1415580:LOC115474223
gene id: 1415580:LOC115474223
uniprot id: A0A6P7YKE8
uniprot id: A0A6P7YQQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tango11 family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface.

1415580:LOC115461157
gene id: 1415580:LOC115461157
uniprot id: A0A6P7X2D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

1415580:SDHB
gene id: 1415580:SDHB
uniprot id: A0A6P7ZJM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

1415580:PC
gene id: 1415580:PC
uniprot id: A0A6P7Z9Y4
uniprot id: A0A6P7ZP32
uniprot id: A0A6P7ZRF6
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1415580:AGBL1
gene id: 1415580:AGBL1
uniprot id: A0A6P7X4V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

1415580:PTGR2
gene id: 1415580:PTGR2
uniprot id: A0A6P7YUJ7
uniprot id: A0A6P7Z552
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADP-dependent oxidoreductase L4BD family.
messages: Cytoplasm
messages: Monomer.

1415580:SLC26A2
gene id: 1415580:SLC26A2
uniprot id: A0A6P7YU73
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sulfate transporter. May play a role in endochondral bone formation.

1415580:TRPC1
gene id: 1415580:TRPC1
uniprot id: A0A6P7Z6U2
uniprot id: A0A6P7ZA73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC1 sub-subfamily.
messages: Membrane
messages: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.

1415580:ORMDL2
gene id: 1415580:ORMDL2
uniprot id: A0A6P7XAH6
uniprot id: A0A6P7XJE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

1415580:LOC115478934
gene id: 1415580:LOC115478934
uniprot id: A0A6P7Z754
uniprot id: A0A6P7ZAM0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:ILDR2
gene id: 1415580:ILDR2
uniprot id: A0A6P7Y402
uniprot id: A0A6P7Y4K4
uniprot id: A0A6P7Y9R3
uniprot id: A0A6P7YAF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

1415580:LOC115476308
gene id: 1415580:LOC115476308
uniprot id: A0A6P7YYX2
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

1415580:LOC115481217
gene id: 1415580:LOC115481217
uniprot id: A0A6P7WV85
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1415580:AMIGO1
gene id: 1415580:AMIGO1
uniprot id: A0A6P7ZUV2
names: Similarity
messages: Belongs to the immunoglobulin superfamily. AMIGO family.

1415580:CUL5
gene id: 1415580:CUL5
uniprot id: A0A6P7XSU4
names: Similarity
messages: Belongs to the cullin family.

1415580:COL4A1
gene id: 1415580:COL4A1
uniprot id: A0A6P7Y3K5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

1415580:PEX3
gene id: 1415580:PEX3
uniprot id: A0A6P7XP91
uniprot id: A0A6P7XV53
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with PEX19.
messages: Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in the peroxisomes.
messages: Peroxisome membrane

1415580:LOC115464915
gene id: 1415580:LOC115464915
uniprot id: A0A6P7XKH8
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115469711
gene id: 1415580:LOC115469711
uniprot id: A0A6P7Y0L7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:MAPK1IP1L
gene id: 1415580:MAPK1IP1L
uniprot id: A0A6P7Z264
names: Similarity
messages: Belongs to the MISS family.

1415580:SYNE3
gene id: 1415580:SYNE3
uniprot id: A0A6P7YZ21
names: Similarity
messages: Belongs to the nesprin family.

1415580:LOC115456559
gene id: 1415580:LOC115456559
uniprot id: A0A6P7WKR8
uniprot id: A0A6P7WMQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

1415580:GABARAPL2
gene id: 1415580:GABARAPL2
uniprot id: A0A6P7Y6C9
names: Similarity
messages: Belongs to the ATG8 family.

1415580:LOC115461329
gene id: 1415580:LOC115461329
uniprot id: A0A6P7X0L0
names: Similarity
messages: Belongs to the SNF7 family.

1415580:LOC115468078
gene id: 1415580:LOC115468078
uniprot id: A0A6P7XXL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Secreted

1415580:LYPD6
gene id: 1415580:LYPD6
uniprot id: A0A6P7YSA7
uniprot id: A0A6P7YSF5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:PREPL
gene id: 1415580:PREPL
uniprot id: A0A6P7XMP0
names: Similarity
messages: Belongs to the peptidase S9A family.

1415580:EEF2
gene id: 1415580:EEF2
uniprot id: A0A6P7ZG49
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1415580:LOC115458435
gene id: 1415580:LOC115458435
uniprot id: A0A6P7WLU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:SMG8
gene id: 1415580:SMG8
uniprot id: A0A6P7WEV1
names: Function
names: Similarity
messages: Belongs to the SMG8 family.
messages: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.

1415580:CLIC4
gene id: 1415580:CLIC4
uniprot id: A0A6P7Z3Q1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

1415580:LOC115481161
gene id: 1415580:LOC115481161
uniprot id: A0A6P7X5J9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1415580:LOC115458016
gene id: 1415580:LOC115458016
uniprot id: A0A6P7WT95
uniprot id: A0A6P7X0G1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1415580:RPLP1
gene id: 1415580:RPLP1
uniprot id: A0A6P7Z7W0
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

1415580:ACSF2
gene id: 1415580:ACSF2
uniprot id: A0A6P7YGX6
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

1415580:KCNK10
gene id: 1415580:KCNK10
uniprot id: A0A6P7YTC6
uniprot id: A0A6P7Z115
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

1415580:PPP1R1C
gene id: 1415580:PPP1R1C
uniprot id: A0A6P7YRD8
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 1 family.

1415580:DPM3
gene id: 1415580:DPM3
uniprot id: A0A6P7WQF4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM3 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER.

1415580:B3GLCT
gene id: 1415580:B3GLCT
uniprot id: A0A6P7Y0C2
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115478989
gene id: 1415580:LOC115478989
uniprot id: A0A6P7Z7E4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1415580:PACSIN2
gene id: 1415580:PACSIN2
uniprot id: A0A6P7YW67
uniprot id: A0A6P7Z268
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PACSIN family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Early endosome
messages: Endosome membrane
messages: Recycling endosome membrane
messages: caveola
messages: cytoskeleton
messages: ruffle membrane

1415580:DRAM2
gene id: 1415580:DRAM2
uniprot id: A0A6P7ZQD6
names: Subcellular Location Annotation
messages: Membrane

1415580:NEUROD1
gene id: 1415580:NEUROD1
uniprot id: A0A6P7YM47
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

1415580:FUBP1
gene id: 1415580:FUBP1
uniprot id: A0A6P7Y4E2
uniprot id: A0A6P7YBG3
uniprot id: A0A6P7YH74
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115466824
gene id: 1415580:LOC115466824
uniprot id: A0A6P7XUS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115478128
gene id: 1415580:LOC115478128
uniprot id: A0A6P7Z749
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

1415580:FGF9
gene id: 1415580:FGF9
uniprot id: A0A6P7XL87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Secreted

1415580:PIGV
gene id: 1415580:PIGV
uniprot id: A0A6P7ZFE8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGV family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.
messages: Membrane

1415580:LOC115468859
gene id: 1415580:LOC115468859
uniprot id: A0A6P7Y1U6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

1415580:LOC115458138
gene id: 1415580:LOC115458138
uniprot id: A0A6P7WZZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

1415580:GDE1
gene id: 1415580:GDE1
uniprot id: A0A6P7Z0Z1
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

1415580:MINDY1
gene id: 1415580:MINDY1
uniprot id: A0A6P7WHZ2
uniprot id: A0A6P7WP98
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM63 subfamily.
messages: Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for long polyubiquitin chains. May play a regulatory role at the level of protein turnover.

1415580:LOC115481983
gene id: 1415580:LOC115481983
uniprot id: A0A6P7ZI38
uniprot id: A0A6P7ZI68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:KIF14
gene id: 1415580:KIF14
uniprot id: A0A6P7YCZ1
uniprot id: A0A6P7YDA7
uniprot id: A0A6P7YJ21
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

1415580:CAPN6
gene id: 1415580:CAPN6
uniprot id: A0A6P7YMW8
names: Similarity
messages: Belongs to the peptidase C2 family.

1415580:THNSL1
gene id: 1415580:THNSL1
uniprot id: A0A6P7XRM5
names: Similarity
messages: Belongs to the threonine synthase family.

1415580:NDUFA6
gene id: 1415580:NDUFA6
uniprot id: A0A6P7XT89
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I LYR family.
messages: Mammalian complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

1415580:ADAM15
gene id: 1415580:ADAM15
uniprot id: A0A6P7WI69
uniprot id: A0A6P7WPI9
uniprot id: A0A6P7WRI7
uniprot id: A0A6P7WXJ5
uniprot id: A0A6P7WYJ1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115468355
gene id: 1415580:LOC115468355
uniprot id: A0A6P7XYP9
uniprot id: A0A6P7XZD5
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

1415580:LOC115482125
gene id: 1415580:LOC115482125
uniprot id: A0A6P7ZVA4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115457011
gene id: 1415580:LOC115457011
uniprot id: A0A6P7WGC9
names: Subcellular Location Annotation
messages: Nucleus

1415580:SCARA5
gene id: 1415580:SCARA5
uniprot id: A0A6P7XG81
uniprot id: A0A6P7XPR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCARA5 family.
messages: Cell membrane
messages: Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways.
messages: Homotrimer.
messages: Membrane

1415580:INPP4B
gene id: 1415580:INPP4B
uniprot id: A0A6P7X6L9
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

1415580:HTR1F
gene id: 1415580:HTR1F
uniprot id: A0A6P7Y597
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
messages: Membrane

1415580:LOC115475484
gene id: 1415580:LOC115475484
uniprot id: A0A6P7YI31
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

1415580:FERMT3
gene id: 1415580:FERMT3
uniprot id: A0A6P7ZI03
names: Similarity
messages: Belongs to the kindlin family.

1415580:LOC115471270
gene id: 1415580:LOC115471270
uniprot id: A0A6P7XZN0
names: Similarity
messages: Belongs to the hexokinase family.

1415580:UBE2D4
gene id: 1415580:UBE2D4
uniprot id: A0A6P7XXF8
uniprot id: A0A6P7Y3M8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

1415580:CAMTA1
gene id: 1415580:CAMTA1
uniprot id: A0A6P7WFJ7
names: Similarity
names: Subunit
messages: Belongs to the CAMTA family.
messages: May interact with calmodulin.

1415580:USP11
gene id: 1415580:USP11
uniprot id: A0A6P7X2F5
uniprot id: A0A6P7XB59
uniprot id: A0A6P7XHK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Nucleus

1415580:ARL5A
gene id: 1415580:ARL5A
uniprot id: A0A6P7YMY4
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

1415580:LOC115471937
gene id: 1415580:LOC115471937
uniprot id: A0A6P7Y2Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

1415580:VARS2
gene id: 1415580:VARS2
uniprot id: A0A6P7XCE6
uniprot id: A0A6P7XRF4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1415580:LOC115468277
gene id: 1415580:LOC115468277
uniprot id: A0A6P7XJT5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Converts sphingomyelin to ceramide.
messages: Secreted

1415580:SPATS2
gene id: 1415580:SPATS2
uniprot id: A0A6P7XAQ4
uniprot id: A0A6P7XJK6
uniprot id: A0A6P7XQI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPATS2 family.
messages: Cytoplasm

1415580:SSR2
gene id: 1415580:SSR2
uniprot id: A0A6P7WP29
uniprot id: A0A6P7WR27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-beta family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

1415580:SEC16B
gene id: 1415580:SEC16B
uniprot id: A0A6P7Y2V6
uniprot id: A0A6P7Y9Y0
uniprot id: A0A6P7YG46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC16 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.
messages: SEC16A and SEC16B are each present in multiple copies in a heteromeric complex.

1415580:ZNF503
gene id: 1415580:ZNF503
uniprot id: A0A6P7XUE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

1415580:LRRFIP2
gene id: 1415580:LRRFIP2
uniprot id: A0A6P7Y1P3
uniprot id: A0A6P7Y8V4
uniprot id: A0A6P7Y8Z3
uniprot id: A0A6P7Y908
uniprot id: A0A6P7YED7
uniprot id: A0A6P7YF16
names: Similarity
messages: Belongs to the LRRFIP family.

1415580:VDAC1
gene id: 1415580:VDAC1
uniprot id: A0A6P7YX45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Cell membrane
messages: Membrane
messages: Membrane raft

1415580:LOC115480240
gene id: 1415580:LOC115480240
uniprot id: A0A6P7Z5M4
uniprot id: A0A6P7Z5M9
uniprot id: A0A6P7ZAK8
uniprot id: A0A6P7ZAL2
uniprot id: A0A6P7ZDR4
uniprot id: A0A6P7ZDR8
uniprot id: A0A6P7ZGB9
uniprot id: A0A6P7ZGC6
uniprot id: A0A6P7ZGT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

1415580:ADAM19
gene id: 1415580:ADAM19
uniprot id: A0A6P7YZQ2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:FOXI1
gene id: 1415580:FOXI1
uniprot id: A0A6P7YW39
names: Subcellular Location Annotation
messages: Nucleus

1415580:CAPNS1
gene id: 1415580:CAPNS1
uniprot id: A0A6P7ZB65
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer or heterodimer of a large (catalytic) and a small (regulatory) subunit. In presence of calcium, the heterodimer dissociates.
messages: Membrane

1415580:NTS
gene id: 1415580:NTS
uniprot id: A0A6P7Z4P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurotensin family.
messages: Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.
messages: Secreted
messages: Vesicle
messages: secretory vesicle

1415580:OC90
gene id: 1415580:OC90
uniprot id: A0A6P7WZV4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

1415580:UCKL1
gene id: 1415580:UCKL1
uniprot id: A0A6P7YT82
uniprot id: A0A6P7YXH5
uniprot id: A0A6P7YY10
names: Similarity
messages: Belongs to the uridine kinase family.

1415580:LOC115475158
gene id: 1415580:LOC115475158
uniprot id: A0A6P7YP14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

1415580:SLC15A3
gene id: 1415580:SLC15A3
uniprot id: A0A6P7ZW29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1415580:MMP21
gene id: 1415580:MMP21
uniprot id: A0A6P7XZL8
names: Similarity
messages: Belongs to the peptidase M10A family.

1415580:LOC115456970
gene id: 1415580:LOC115456970
uniprot id: A0A6P7WME4
names: Similarity
messages: Belongs to the ARTD/PARP family.

1415580:ANXA2
gene id: 1415580:ANXA2
uniprot id: A0A6P7WT02
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Membrane
messages: basement membrane

1415580:LOC115481440
gene id: 1415580:LOC115481440
uniprot id: A0A6P7ZMG6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

1415580:SLC18A1
gene id: 1415580:SLC18A1
uniprot id: A0A6P7Y438
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Vesicular transporter family.
messages: Membrane

1415580:SLAIN1
gene id: 1415580:SLAIN1
uniprot id: A0A6P7XM71
uniprot id: A0A6P7XTW2
uniprot id: A0A6P7XV99
uniprot id: A0A6P7Y0V0
names: Similarity
messages: Belongs to the SLAIN motif-containing family.

1415580:GLRA4
gene id: 1415580:GLRA4
uniprot id: A0A6P7YLN5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

1415580:LOC115468841
gene id: 1415580:LOC115468841
uniprot id: A0A6P7XUS8
uniprot id: A0A6P7XW40
uniprot id: A0A6P7Y126
uniprot id: A0A6P7Y1N1
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1415580:MRPL9
gene id: 1415580:MRPL9
uniprot id: A0A6P7WUI1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.

1415580:SYN1
gene id: 1415580:SYN1
uniprot id: A0A6P7X2G5
uniprot id: A0A6P7XB70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synapsin family.
messages: Golgi apparatus
messages: Presynapse
messages: Synapse
messages: Vesicle
messages: synaptic vesicle

1415580:LOC115481119
gene id: 1415580:LOC115481119
uniprot id: A0A6P7ZJN6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Contains 1 lysine tyrosylquinone.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

1415580:LOC115474419
gene id: 1415580:LOC115474419
uniprot id: A0A6P7YLR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

1415580:MPP6
gene id: 1415580:MPP6
uniprot id: A0A6P7XR72
uniprot id: A0A6P7Y483
uniprot id: A0A6P7Y506
uniprot id: A0A6P7Y574
names: Similarity
messages: Belongs to the MAGUK family.

1415580:TRIM45
gene id: 1415580:TRIM45
uniprot id: A0A6P7XZZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIM/RBCC family.
messages: Cytoplasm

1415580:LOC115469917
gene id: 1415580:LOC115469917
uniprot id: A0A6P7Y619
names: Subcellular Location Annotation
messages: Nucleus

1415580:RRAD
gene id: 1415580:RRAD
uniprot id: A0A6P7XZY3
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

1415580:TTYH3
gene id: 1415580:TTYH3
uniprot id: A0A6P7YN49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

1415580:LOC115471584
gene id: 1415580:LOC115471584
uniprot id: A0A6P7Y848
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:SEC31A
gene id: 1415580:SEC31A
uniprot id: A0A6P7WTI5
uniprot id: A0A6P7WZB8
uniprot id: A0A6P7WZC2
uniprot id: A0A6P7X1X4
uniprot id: A0A6P7X7B9
uniprot id: A0A6P7X7C3
uniprot id: A0A6P7X8N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC31 family.
messages: Endoplasmic reticulum membrane

1415580:MRPS12
gene id: 1415580:MRPS12
uniprot id: A0A6P7ZCV4
uniprot id: A0A6P7ZLB9
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

1415580:LOC115473910
gene id: 1415580:LOC115473910
uniprot id: A0A6P7YBU7
uniprot id: A0A6P7YJ86
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

1415580:VCAN
gene id: 1415580:VCAN
uniprot id: A0A6P7XEY8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

1415580:HJV
gene id: 1415580:HJV
uniprot id: A0A6P7WRF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

1415580:ALDH1A2
gene id: 1415580:ALDH1A2
uniprot id: A0A6P7WWP3
uniprot id: A0A6P7X2F6
uniprot id: A0A6P7X2H4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1415580:LZTFL1
gene id: 1415580:LZTFL1
uniprot id: A0A6P7Y5A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LZTFL1 family.
messages: Cytoplasm
messages: Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function.
messages: Self-associates. Interacts with BBS9; the interaction mediates the association of LZTL1 with the BBsome complex and regulates BBSome ciliary trafficking.

1415580:TMEM132A
gene id: 1415580:TMEM132A
uniprot id: A0A6P7ZFF0
uniprot id: A0A6P7ZW16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

1415580:DLK1
gene id: 1415580:DLK1
uniprot id: A0A6P7YW33
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115460529
gene id: 1415580:LOC115460529
uniprot id: A0A6P7WYC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115456748
gene id: 1415580:LOC115456748
uniprot id: A0A6P7WLH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GST superfamily. Pi family.
messages: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
messages: Cytoplasm
messages: Homodimer.
messages: Mitochondrion
messages: Nucleus

1415580:CSGALNACT1
gene id: 1415580:CSGALNACT1
uniprot id: A0A6P7XI78
uniprot id: A0A6P7XJA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

1415580:HIP1
gene id: 1415580:HIP1
uniprot id: A0A6P7ZX41
uniprot id: A0A6P8A0V9
names: Similarity
messages: Belongs to the SLA2 family.

1415580:MCUB
gene id: 1415580:MCUB
uniprot id: A0A6P7WU25
uniprot id: A0A6P7X7W3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCU (TC 1.A.77) family.
messages: Forms a well-packed pentamer with an overall cylindrical shape. The inner core of the pentamer is formed with the second transmembrane region and the second coiled-coil region: while the transmembrane regions pack into a five-helix bundle having a largely polar pore across the membrane, the coiled-coil outside the membrane forms a pentamer with a hydrophobic core. The inner core is wrapped by the first transmembrane region through contacts between the first and the second transmembrane regions. The second transmembrane is followed by the inner juxtamembrane region (IJMH) that orients at a wide angle relative to the second transmembrane. The two core domains are held together on the periphery by the outer juxtamembrane helix (OJMH).
messages: Membrane
messages: Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
messages: Mitochondrion inner membrane

1415580:PLXNC1
gene id: 1415580:PLXNC1
uniprot id: A0A6P7Z469
names: Caution
names: Similarity
messages: Belongs to the plexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:EME1
gene id: 1415580:EME1
uniprot id: A0A6P7Y9Q1
uniprot id: A0A6P7YGW6
uniprot id: A0A6P7YMB9
names: Similarity
messages: Belongs to the EME1/MMS4 family.

1415580:SSBP4
gene id: 1415580:SSBP4
uniprot id: A0A6P7Z5I4
uniprot id: A0A6P7ZDL7
names: Subcellular Location Annotation
messages: Nucleus

1415580:AP1S2
gene id: 1415580:AP1S2
uniprot id: A0A6P7XRZ9
uniprot id: A0A6P7XZ54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

1415580:ZER1
gene id: 1415580:ZER1
uniprot id: A0A6P7YFE8
uniprot id: A0A6P7YL78
names: Similarity
messages: Belongs to the zyg-11 family.

1415580:CMC1
gene id: 1415580:CMC1
uniprot id: A0A6P7XC29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

1415580:LOC115481126
gene id: 1415580:LOC115481126
uniprot id: A0A6P7Z9L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Membrane
messages: Microsome membrane

1415580:LOC115477787
gene id: 1415580:LOC115477787
uniprot id: A0A6P7Z5J9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:ENTPD5
gene id: 1415580:ENTPD5
uniprot id: A0A6P7YQY1
uniprot id: A0A6P7YXL7
uniprot id: A0A6P7YYR5
uniprot id: A0A6P7Z1L6
uniprot id: A0A6P7Z2J8
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

1415580:LOC115474075
gene id: 1415580:LOC115474075
uniprot id: A0A6P7YK91
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:PES1
gene id: 1415580:PES1
uniprot id: A0A6P7ZL09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pescadillo family.
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

1415580:PITX1
gene id: 1415580:PITX1
uniprot id: A0A6P7YTD5
uniprot id: A0A6P7YXF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

1415580:LOC115480841
gene id: 1415580:LOC115480841
uniprot id: A0A6P7ZNM0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LOC115457190
gene id: 1415580:LOC115457190
uniprot id: A0A6P7WQ28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 5A family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

1415580:ELL2
gene id: 1415580:ELL2
uniprot id: A0A6P7X7I8
uniprot id: A0A6P7XF34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

1415580:CLDN1
gene id: 1415580:CLDN1
uniprot id: A0A6P7Z698
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

1415580:LOC115480734
gene id: 1415580:LOC115480734
uniprot id: A0A6P7ZMZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

1415580:LAMB4
gene id: 1415580:LAMB4
uniprot id: A0A6P7YZT1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

1415580:GCM2
gene id: 1415580:GCM2
uniprot id: A0A6P7X6W7
names: Subcellular Location Annotation
messages: Nucleus

1415580:SIAH1
gene id: 1415580:SIAH1
uniprot id: A0A6P7XXT9
uniprot id: A0A6P7YB07
uniprot id: A0A6P7YBL9
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

1415580:MBLAC1
gene id: 1415580:MBLAC1
uniprot id: A0A6P7WSI6
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

1415580:GPD1
gene id: 1415580:GPD1
uniprot id: A0A6P7XTV2
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

1415580:FGF17
gene id: 1415580:FGF17
uniprot id: A0A6P7XQY6
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

1415580:LOC115457063
gene id: 1415580:LOC115457063
uniprot id: A0A6P7WGH5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:EPS8L1
gene id: 1415580:EPS8L1
uniprot id: A0A6P7XKM2
names: Similarity
messages: Belongs to the EPS8 family.

1415580:DOCK10
gene id: 1415580:DOCK10
uniprot id: A0A6P7Z955
names: Similarity
messages: Belongs to the DOCK family.

1415580:VWCE
gene id: 1415580:VWCE
uniprot id: A0A6P7XNR6
uniprot id: A0A6P7XWU1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115457307
gene id: 1415580:LOC115457307
uniprot id: A0A6P7WXE1
names: Subcellular Location Annotation
messages: Membrane

1415580:RPS9
gene id: 1415580:RPS9
uniprot id: A0A6P7XDY7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs.

1415580:LOC115464462
gene id: 1415580:LOC115464462
uniprot id: A0A6P7XBN0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:CHL1
gene id: 1415580:CHL1
uniprot id: A0A6P7YA88
uniprot id: A0A6P7YHF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
messages: Membrane

1415580:LOC115462706
gene id: 1415580:LOC115462706
uniprot id: A0A6P7X7Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm

1415580:LOC115464412
gene id: 1415580:LOC115464412
uniprot id: A0A6P7XDP4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:RNASEH2A
gene id: 1415580:RNASEH2A
uniprot id: A0A6P7XQ46
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family. Eukaryotic subfamily.
messages: Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1415580:FSCN1
gene id: 1415580:FSCN1
uniprot id: A0A6P7YWS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

1415580:NFASC
gene id: 1415580:NFASC
uniprot id: A0A6P7ZAQ6
uniprot id: A0A6P7ZF20
uniprot id: A0A6P7ZF22
uniprot id: A0A6P7ZMF7
uniprot id: A0A6P7ZQI9
uniprot id: A0A6P7ZQK0
uniprot id: A0A6P7ZT72
uniprot id: A0A6P7ZT82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
messages: Membrane

1415580:CNR2
gene id: 1415580:CNR2
uniprot id: A0A6P7Z7J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:EIPR1
gene id: 1415580:EIPR1
uniprot id: A0A6P7XH10
names: Similarity
messages: Belongs to the WD repeat EIPR1 family.

1415580:LOC115458205
gene id: 1415580:LOC115458205
uniprot id: A0A6P7WRW9
names: Subcellular Location Annotation
messages: Membrane

1415580:NDUFAF7
gene id: 1415580:NDUFAF7
uniprot id: A0A6P7XFQ1
uniprot id: A0A6P7XKX0
uniprot id: A0A6P7XLU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Belongs to the NDUFAF7 family.
messages: Mitochondrion

1415580:CD164
gene id: 1415580:CD164
uniprot id: A0A6P7XX60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD164 family.
messages: Membrane

1415580:SAMHD1
gene id: 1415580:SAMHD1
uniprot id: A0A6P7YRX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAMHD1 family.
messages: Chromosome

1415580:PTPN4
gene id: 1415580:PTPN4
uniprot id: A0A6P7YEE5
uniprot id: A0A6P7YLD4
uniprot id: A0A6P7YM13
uniprot id: A0A6P7YRL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

1415580:LOC115473836
gene id: 1415580:LOC115473836
uniprot id: A0A6P7YNN8
uniprot id: A0A6P7YP37
names: Similarity
messages: Belongs to the GroES chaperonin family.

1415580:AGXT
gene id: 1415580:AGXT
uniprot id: A0A6P7Z539
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1415580:MDK
gene id: 1415580:MDK
uniprot id: A0A6P7XW20
uniprot id: A0A6P7Y103
names: Similarity
messages: Belongs to the pleiotrophin family.

1415580:ELAVL3
gene id: 1415580:ELAVL3
uniprot id: A0A6P7XI07
uniprot id: A0A6P7XQ99
names: Similarity
messages: Belongs to the RRM elav family.

1415580:FAM133B
gene id: 1415580:FAM133B
uniprot id: A0A6P7Y6I9
names: Similarity
messages: Belongs to the FAM133 family.

1415580:AGBL4
gene id: 1415580:AGBL4
uniprot id: A0A6P7Y306
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

1415580:EVC
gene id: 1415580:EVC
uniprot id: A0A6P7X0Z6
uniprot id: A0A6P7X900
names: Subcellular Location Annotation
messages: Membrane
messages: cilium basal body
messages: cilium membrane

1415580:LOC115461969
gene id: 1415580:LOC115461969
uniprot id: A0A6P7XCJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:UTP14A
gene id: 1415580:UTP14A
uniprot id: A0A6P7YKM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP14 family.
messages: nucleolus

1415580:PLPBP
gene id: 1415580:PLPBP
uniprot id: A0A6P7XR00
uniprot id: A0A6P7XZ06
names: Caution
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.

1415580:LOC115481093
gene id: 1415580:LOC115481093
uniprot id: A0A6P7Z9H7
uniprot id: A0A6P7ZDX2
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

1415580:DDIT4L
gene id: 1415580:DDIT4L
uniprot id: A0A6P7WZP8
names: Similarity
messages: Belongs to the DDIT4 family.

1415580:SKI
gene id: 1415580:SKI
uniprot id: A0A6P7WLA7
names: Similarity
messages: Belongs to the SKI family.

1415580:SRP72
gene id: 1415580:SRP72
uniprot id: A0A6P7XI84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP72 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
messages: Cytoplasm

1415580:DYNLRB2
gene id: 1415580:DYNLRB2
uniprot id: A0A6P7XSV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
messages: Belongs to the GAMAD family.
messages: cytoskeleton

1415580:JAGN1
gene id: 1415580:JAGN1
uniprot id: A0A6P7YHA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the jagunal family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:LOC115481011
gene id: 1415580:LOC115481011
uniprot id: A0A6P7Z946
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

1415580:LOC115475927
gene id: 1415580:LOC115475927
uniprot id: A0A6P7YT37
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1415580:GOLGA5
gene id: 1415580:GOLGA5
uniprot id: A0A6P7YZH8
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport.
messages: Membrane

1415580:HOMER2
gene id: 1415580:HOMER2
uniprot id: A0A6P7WQJ1
uniprot id: A0A6P7WZ12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

1415580:LOC115457934
gene id: 1415580:LOC115457934
uniprot id: A0A6P7WJK8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:SORCS3
gene id: 1415580:SORCS3
uniprot id: A0A6P7YCM6
names: Similarity
messages: Belongs to the VPS10-related sortilin family. SORCS subfamily.

1415580:KMT2A
gene id: 1415580:KMT2A
uniprot id: A0A6P7ZB28
uniprot id: A0A6P7ZFD6
uniprot id: A0A6P7ZNC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.
messages: Nucleus

1415580:LOC115480542
gene id: 1415580:LOC115480542
uniprot id: A0A6P7Z721
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

1415580:RGMB
gene id: 1415580:RGMB
uniprot id: A0A6P7WX72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

1415580:CHST3
gene id: 1415580:CHST3
uniprot id: A0A6P7Y2C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

1415580:LOC115464969
gene id: 1415580:LOC115464969
uniprot id: A0A6P7XDA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

1415580:IKBKE
gene id: 1415580:IKBKE
uniprot id: A0A6P7ZEE7
names: Subcellular Location Annotation
messages: Cytoplasm

1415580:TM4SF4
gene id: 1415580:TM4SF4
uniprot id: A0A6P7ZBA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

1415580:LOC115477152
gene id: 1415580:LOC115477152
uniprot id: A0A6P7Z1J8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

1415580:DNAJA1
gene id: 1415580:DNAJA1
uniprot id: A0A6P7X3M5
names: Subcellular Location Annotation
messages: Membrane

1415580:SPIRE1
gene id: 1415580:SPIRE1
uniprot id: A0A6P7YLE0
uniprot id: A0A6P7YTD3
uniprot id: A0A6P7YTF9
uniprot id: A0A6P7YUA9
uniprot id: A0A6P7YUC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spire family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytoskeleton

1415580:ATL2
gene id: 1415580:ATL2
uniprot id: A0A6P7XG24
uniprot id: A0A6P7XND1
uniprot id: A0A6P7XNZ7
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

1415580:PDE4A
gene id: 1415580:PDE4A
uniprot id: A0A6P7X6C5
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

1415580:HIKESHI
gene id: 1415580:HIKESHI
uniprot id: A0A6P7XZ26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus.
messages: Belongs to the OPI10 family.
messages: Cytoplasm
messages: Forms an asymmetric homodimer; required for binding and nuclear import of HSP70 proteins. Interacts with ATP-bound HSP70 proteins.
messages: Nucleus
messages: cytosol

1415580:TBCA
gene id: 1415580:TBCA
uniprot id: A0A6P7X0N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCA family.
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.
messages: Tubulin-folding protein; involved in the early step of the tubulin folding pathway.
messages: cytoskeleton

1415580:SDHAF4
gene id: 1415580:SDHAF4
uniprot id: A0A6P7XVZ7
names: Similarity
messages: Belongs to the SDHAF4 family.

1415580:LOC115470054
gene id: 1415580:LOC115470054
uniprot id: A0A6P7Y1U3
uniprot id: A0A6P7Y6Q3
uniprot id: A0A6P7Y7T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX15/CtaA family.
messages: Membrane

1415580:IDH3B
gene id: 1415580:IDH3B
uniprot id: A0A6P7X2V7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

1415580:CNOT7
gene id: 1415580:CNOT7
uniprot id: A0A6P7X4D0
uniprot id: A0A6P7X9Q4
uniprot id: A0A6P7XB06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

1415580:LOC115465711
gene id: 1415580:LOC115465711
uniprot id: A0A6P7XGI1
uniprot id: A0A6P7XIM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAIF1 family.
messages: Induces apoptosis.
messages: Nucleus

1415580:LOC115475132
gene id: 1415580:LOC115475132
uniprot id: A0A6P7YPS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:PSMD3
gene id: 1415580:PSMD3
uniprot id: A0A6P7ZVL7
names: Similarity
messages: Belongs to the proteasome subunit S3 family.

1415580:MIPEP
gene id: 1415580:MIPEP
uniprot id: A0A6P7XL92
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1415580:LOC115457615
gene id: 1415580:LOC115457615
uniprot id: A0A6P7WXH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane

1415580:MEGF9
gene id: 1415580:MEGF9
uniprot id: A0A6P7YGY8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:CDCA8
gene id: 1415580:CDCA8
uniprot id: A0A6P7Z6I2
uniprot id: A0A6P7ZBE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the borealin family.
messages: centromere

1415580:DNTTIP1
gene id: 1415580:DNTTIP1
uniprot id: A0A6P7YM52
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115482582
gene id: 1415580:LOC115482582
uniprot id: A0A6P7ZW22
names: Similarity
messages: Belongs to the peptidase C14A family.

1415580:LOC115458156
gene id: 1415580:LOC115458156
uniprot id: A0A6P7X144
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:DACT1
gene id: 1415580:DACT1
uniprot id: A0A6P7Z2X3
uniprot id: A0A6P7Z5Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dapper family.
messages: Cytoplasm

1415580:CDK5R1
gene id: 1415580:CDK5R1
uniprot id: A0A6P7ZV06
names: Similarity
names: Subunit
messages: Belongs to the cyclin-dependent kinase 5 activator family.
messages: Heterodimer of a catalytic subunit and a regulatory subunit.

1415580:LOC115479598
gene id: 1415580:LOC115479598
uniprot id: A0A6P7Z299
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: gap junction

1415580:CDS2
gene id: 1415580:CDS2
uniprot id: A0A6P7XJ02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Membrane

1415580:KLC4
gene id: 1415580:KLC4
uniprot id: A0A6P7X7L0
uniprot id: A0A6P7XEB3
uniprot id: A0A6P7XEB6
uniprot id: A0A6P7XGE8
uniprot id: A0A6P7XMF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

1415580:LOC115457260
gene id: 1415580:LOC115457260
uniprot id: A0A6P7WQ90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:VPS36
gene id: 1415580:VPS36
uniprot id: A0A6P7XZY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS36 family.
messages: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).
messages: Cytoplasm
messages: Endosome

1415580:LOC115463559
gene id: 1415580:LOC115463559
uniprot id: A0A6P7X3A1
names: Similarity
messages: Belongs to the perilipin family.

1415580:MRPS10
gene id: 1415580:MRPS10
uniprot id: A0A6P7XMU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Mitochondrion

1415580:LOC115464440
gene id: 1415580:LOC115464440
uniprot id: A0A6P7XJ53
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:RNF13
gene id: 1415580:RNF13
uniprot id: A0A6P7Z5X0
names: Subcellular Location Annotation
messages: Membrane

1415580:GALR3
gene id: 1415580:GALR3
uniprot id: A0A6P7Z2X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

1415580:LOC115474662
gene id: 1415580:LOC115474662
uniprot id: A0A6P7YS87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
messages: May be involved in iron transport and iron homeostasis.
messages: Membrane

1415580:POLR3C
gene id: 1415580:POLR3C
uniprot id: A0A6P7WQT9
uniprot id: A0A6P7WYY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC3/POLR3C RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

1415580:BRMS1
gene id: 1415580:BRMS1
uniprot id: A0A6P7Z6E1
uniprot id: A0A6P7ZHM2
names: Subcellular Location Annotation
messages: Nucleus

1415580:UBE2C
gene id: 1415580:UBE2C
uniprot id: A0A6P7YX80
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

1415580:NOTO
gene id: 1415580:NOTO
uniprot id: A0A6P7X6E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-gamma family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: Nucleus
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

1415580:ACYP2
gene id: 1415580:ACYP2
uniprot id: A0A6P7XM07
names: Similarity
messages: Belongs to the acylphosphatase family.

1415580:TOE1
gene id: 1415580:TOE1
uniprot id: A0A6P7YDD0
names: Similarity
messages: Belongs to the CAF1 family.

1415580:ENPP2
gene id: 1415580:ENPP2
uniprot id: A0A6P7Z4L2
uniprot id: A0A6P7Z4M6
uniprot id: A0A6P7Z4S2
uniprot id: A0A6P7Z9Q5
uniprot id: A0A6P7Z9R6
uniprot id: A0A6P7Z9U6
uniprot id: A0A6P7ZCQ0
uniprot id: A0A6P7ZCT1
uniprot id: A0A6P7ZCW2
uniprot id: A0A6P7ZFC0
uniprot id: A0A6P7ZFF4
uniprot id: A0A6P7ZFS6
uniprot id: A0A6P7ZG20
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Secreted

1415580:GUCY1A1
gene id: 1415580:GUCY1A1
uniprot id: A0A6P7XA77
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

1415580:CPNE9
gene id: 1415580:CPNE9
uniprot id: A0A6P7YBE3
names: Similarity
messages: Belongs to the copine family.

1415580:SEMA7A
gene id: 1415580:SEMA7A
uniprot id: A0A6P7WR67
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:TP63
gene id: 1415580:TP63
uniprot id: A0A6P7YWE8
uniprot id: A0A6P7Z2C0
uniprot id: A0A6P7Z2C4
uniprot id: A0A6P7Z479
uniprot id: A0A6P7Z6U0
uniprot id: A0A6P7Z6U4
uniprot id: A0A6P7Z7R6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer.
messages: Cytoplasm
messages: Nucleus

1415580:PIP4P2
gene id: 1415580:PIP4P2
uniprot id: A0A6P7Z4G0
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

1415580:URM1
gene id: 1415580:URM1
uniprot id: A0A6P7YFJ2
uniprot id: A0A6P7YLB4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
messages: Belongs to the URM1 family.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of MOCS3, then thiocarboxylated (-COSH) via the rhodanese domain of MOCS3.
messages: Cytoplasm

1415580:PYGL
gene id: 1415580:PYGL
uniprot id: A0A6P7YRN9
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

1415580:LOC115481414
gene id: 1415580:LOC115481414
uniprot id: A0A6P7ZAK9
names: Similarity
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.

1415580:LOC115464584
gene id: 1415580:LOC115464584
uniprot id: A0A6P7XE71
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LOC115464870
gene id: 1415580:LOC115464870
uniprot id: A0A6P7XL85
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1415580:LOC115472973
gene id: 1415580:LOC115472973
uniprot id: A0A6P7YK90
names: Subcellular Location Annotation
messages: Membrane

1415580:ADGRG4
gene id: 1415580:ADGRG4
uniprot id: A0A6P7YRA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

1415580:PIGW
gene id: 1415580:PIGW
uniprot id: A0A6P7WLF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGW family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.

1415580:ARRDC3
gene id: 1415580:ARRDC3
uniprot id: A0A6P7X9R7
names: Similarity
messages: Belongs to the arrestin family.

1415580:PNLDC1
gene id: 1415580:PNLDC1
uniprot id: A0A6P7WEW3
uniprot id: A0A6P7WU01
names: Similarity
messages: Belongs to the CAF1 family.

1415580:TPI1
gene id: 1415580:TPI1
uniprot id: A0A6P7WQW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.
messages: It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
messages: Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.

1415580:IFT46
gene id: 1415580:IFT46
uniprot id: A0A6P7ZS96
uniprot id: A0A6P7ZVI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFT46 family.
messages: cilium
messages: cilium basal body

1415580:PHOX2A
gene id: 1415580:PHOX2A
uniprot id: A0A6P7XRQ1
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115464922
gene id: 1415580:LOC115464922
uniprot id: A0A6P7XLF9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

1415580:CCNO
gene id: 1415580:CCNO
uniprot id: A0A6P7XD85
names: Similarity
messages: Belongs to the cyclin family.

1415580:MYO18A
gene id: 1415580:MYO18A
uniprot id: A0A6P7WF17
uniprot id: A0A6P7WL82
uniprot id: A0A6P7WN61
uniprot id: A0A6P7WU69
uniprot id: A0A6P7WU71
uniprot id: A0A6P7WV79
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115471423
gene id: 1415580:LOC115471423
uniprot id: A0A6P7Y036
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

1415580:LOC115457175
gene id: 1415580:LOC115457175
uniprot id: A0A6P7WQ08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:MID1
gene id: 1415580:MID1
uniprot id: A0A6P7XY29
uniprot id: A0A6P7Y375
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination.
messages: cytoskeleton

1415580:ABCG5
gene id: 1415580:ABCG5
uniprot id: A0A6P7XD82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

1415580:RIC8A
gene id: 1415580:RIC8A
uniprot id: A0A6P7Y1Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.

1415580:CMPK2
gene id: 1415580:CMPK2
uniprot id: A0A6P7XK60
names: Similarity
messages: Belongs to the thymidylate kinase family.

1415580:LOC115464586
gene id: 1415580:LOC115464586
uniprot id: A0A6P7XKI2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LOC115481806
gene id: 1415580:LOC115481806
uniprot id: A0A6P7ZCH7
uniprot id: A0A6P7ZGL6
uniprot id: A0A6P7ZQY6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115469591
gene id: 1415580:LOC115469591
uniprot id: A0A6P7Y557
names: Similarity
messages: Belongs to the peptidase M10A family.

1415580:MED18
gene id: 1415580:MED18
uniprot id: A0A6P7ZFM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 18 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1415580:IL15RA
gene id: 1415580:IL15RA
uniprot id: A0A6P7Z6D5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115473485
gene id: 1415580:LOC115473485
uniprot id: A0A6P7YH42
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

1415580:LOC115464477
gene id: 1415580:LOC115464477
uniprot id: A0A6P7XDV9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:ZNF277
gene id: 1415580:ZNF277
uniprot id: A0A6P7Z6D3
names: Similarity
messages: Belongs to the ZNF277 family.

1415580:DLAT
gene id: 1415580:DLAT
uniprot id: A0A6P7ZQY3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Mitochondrion matrix
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1415580:RBM17
gene id: 1415580:RBM17
uniprot id: A0A6P7Z117
uniprot id: A0A6P7Z8X4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the spliceosome.
messages: Nucleus
messages: Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites.

1415580:LOC115457431
gene id: 1415580:LOC115457431
uniprot id: A0A6P7WWT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

1415580:DGCR2
gene id: 1415580:DGCR2
uniprot id: A0A6P7Z1T1
uniprot id: A0A6P7Z9Q0
uniprot id: A0A6P7ZD37
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115460569
gene id: 1415580:LOC115460569
uniprot id: A0A6P7X6I7
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115461231
gene id: 1415580:LOC115461231
uniprot id: A0A6P7X072
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1415580:LOC115471613
gene id: 1415580:LOC115471613
uniprot id: A0A6P7Y0W6
uniprot id: A0A6P7Y2E3
uniprot id: A0A6P7YDP8
uniprot id: A0A6P7YFP2
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the aldo/keto reductase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

1415580:PANX3
gene id: 1415580:PANX3
uniprot id: A0A6P7ZW08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

1415580:SLC30A1
gene id: 1415580:SLC30A1
uniprot id: A0A6P7XNE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

1415580:LOC115478329
gene id: 1415580:LOC115478329
uniprot id: A0A6P7Z2F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Cytoplasm
messages: Nucleus
messages: Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.

1415580:SNTA1
gene id: 1415580:SNTA1
uniprot id: A0A6P7YUG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

1415580:TLR8
gene id: 1415580:TLR8
uniprot id: A0A6P7Y5F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

1415580:LOC115479024
gene id: 1415580:LOC115479024
uniprot id: A0A6P7Z593
names: Similarity
messages: Belongs to the CND2 H2 (condensin-2 subunit 2) family.

1415580:TCEANC
gene id: 1415580:TCEANC
uniprot id: A0A6P7XIW8
uniprot id: A0A6P7XSD5
uniprot id: A0A6P7XXK0
uniprot id: A0A6P7XYA7
names: Subcellular Location Annotation
messages: Nucleus

1415580:NMUR2
gene id: 1415580:NMUR2
uniprot id: A0A6P7Z0J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

1415580:FAM214A
gene id: 1415580:FAM214A
uniprot id: A0A6P7WPK9
uniprot id: A0A6P7X3J7
uniprot id: A0A6P7X3K1
uniprot id: A0A6P7X3L3
names: Similarity
messages: Belongs to the FAM214 family.

1415580:LOC115456630
gene id: 1415580:LOC115456630
uniprot id: A0A6P7WL18
uniprot id: A0A6P7WV09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Cytoplasm

1415580:MOCS1
gene id: 1415580:MOCS1
uniprot id: A0A6P7X7U8
names: Similarity
messages: In the C-terminal section; belongs to the MoaC family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. MoaA family.

1415580:GNB4
gene id: 1415580:GNB4
uniprot id: A0A6P7Z550
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

1415580:NRP1
gene id: 1415580:NRP1
uniprot id: A0A6P7XP71
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:LOC115469959
gene id: 1415580:LOC115469959
uniprot id: A0A6P7Y677
names: Function
names: Similarity
messages: Belongs to the SHOC2 family.
messages: Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.

1415580:LOC115481928
gene id: 1415580:LOC115481928
uniprot id: A0A6P7ZVG3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

1415580:CHRNA10
gene id: 1415580:CHRNA10
uniprot id: A0A6P7XXZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

1415580:SLC25A21
gene id: 1415580:SLC25A21
uniprot id: A0A6P7Z1F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1415580:GABRA2
gene id: 1415580:GABRA2
uniprot id: A0A6P7X6H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA2 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: dendrite

1415580:C2H5orf63
gene id: 1415580:C2H5orf63
uniprot id: A0A6P7XFK9
names: Similarity
messages: Belongs to the glutaredoxin family.

1415580:LPCAT4
gene id: 1415580:LPCAT4
uniprot id: A0A6P7WII9
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

1415580:LOC115457218
gene id: 1415580:LOC115457218
uniprot id: A0A6P7WX61
names: Subcellular Location Annotation
messages: Membrane

1415580:EIF4G3
gene id: 1415580:EIF4G3
uniprot id: A0A6P7ZF11
uniprot id: A0A6P7ZF21
uniprot id: A0A6P7ZKT4
uniprot id: A0A6P7ZKU5
uniprot id: A0A6P7ZV72
uniprot id: A0A6P7ZV75
uniprot id: A0A6P7ZVU2
uniprot id: A0A6P7ZX87
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4G family.

1415580:DDX6
gene id: 1415580:DDX6
uniprot id: A0A6P7ZLW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family.
messages: Cytoplasm

1415580:HTR5A
gene id: 1415580:HTR5A
uniprot id: A0A6P7XFL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:CD79A
gene id: 1415580:CD79A
uniprot id: A0A6P7YMY3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:ADCY1
gene id: 1415580:ADCY1
uniprot id: A0A6P7YI10
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

1415580:BRCA1
gene id: 1415580:BRCA1
uniprot id: A0A6P7ZV37
names: Subcellular Location Annotation
messages: Chromosome
messages: Cytoplasm

1415580:LOC115463094
gene id: 1415580:LOC115463094
uniprot id: A0A6P7X0U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTCD2 family.
messages: Mitochondrion

1415580:LOC115475752
gene id: 1415580:LOC115475752
uniprot id: A0A6P7YJE4
uniprot id: A0A6P7YS69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

1415580:LOC115464821
gene id: 1415580:LOC115464821
uniprot id: A0A6P7XK85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ripply family.
messages: Nucleus

1415580:RFC1
gene id: 1415580:RFC1
uniprot id: A0A6P7X1B8
uniprot id: A0A6P7X9B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the activator 1 large subunit family.
messages: Nucleus

1415580:TBX19
gene id: 1415580:TBX19
uniprot id: A0A6P7Y751
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

1415580:TTC26
gene id: 1415580:TTC26
uniprot id: A0A6P7Y627
uniprot id: A0A6P7YIV3
names: Similarity
messages: Belongs to the IFT56 family.

1415580:FBN2
gene id: 1415580:FBN2
uniprot id: A0A6P7XCE2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fibrillin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

1415580:LOC115479359
gene id: 1415580:LOC115479359
uniprot id: A0A6P7Z171
uniprot id: A0A6P7ZBQ6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:RELT
gene id: 1415580:RELT
uniprot id: A0A6P7XYS0
uniprot id: A0A6P7XZF7
names: Similarity
messages: Belongs to the RELT family.

1415580:MOS
gene id: 1415580:MOS
uniprot id: A0A6P7WXX9
names: Similarity
messages: Belongs to the protein kinase superfamily.

1415580:LOC115465716
gene id: 1415580:LOC115465716
uniprot id: A0A6P7XII5
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

1415580:DENND11
gene id: 1415580:DENND11
uniprot id: A0A6P7Z7J6
uniprot id: A0A6P7Z8F5
names: Similarity
messages: Belongs to the DENND11 family.

1415580:SLC5A5
gene id: 1415580:SLC5A5
uniprot id: A0A6P7Z8F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1415580:PPP1R14A
gene id: 1415580:PPP1R14A
uniprot id: A0A6P7ZJE8
names: Similarity
messages: Belongs to the PP1 inhibitor family.

1415580:LOC115463335
gene id: 1415580:LOC115463335
uniprot id: A0A6P7XAT5
names: Similarity
messages: Belongs to the thioredoxin family.

1415580:LOC115465848
gene id: 1415580:LOC115465848
uniprot id: A0A6P7XH22
uniprot id: A0A6P7XP85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

1415580:TMEM254
gene id: 1415580:TMEM254
uniprot id: A0A6P7Y6Y0
uniprot id: A0A6P7YD28
names: Subcellular Location Annotation
messages: Membrane

1415580:C1H5orf22
gene id: 1415580:C1H5orf22
uniprot id: A0A6P7YJ91
uniprot id: A0A6P7YJG9
uniprot id: A0A6P7YJN2
names: Similarity
messages: Belongs to the UPF0489 family.

1415580:TBX22
gene id: 1415580:TBX22
uniprot id: A0A6P7YG29
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

1415580:TAF1
gene id: 1415580:TAF1
uniprot id: A0A6P7YT35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF1 family.
messages: Nucleus

1415580:ENPP3
gene id: 1415580:ENPP3
uniprot id: A0A6P7XP17
names: Subcellular Location Annotation
messages: Secreted

1415580:IGFBP4
gene id: 1415580:IGFBP4
uniprot id: A0A6P7ZSB5
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds IGF2 more than IGF1.
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

1415580:PCLAF
gene id: 1415580:PCLAF
uniprot id: A0A6P7WYL8
names: Subcellular Location Annotation
messages: Nucleus
messages: perinuclear region

1415580:MTTP
gene id: 1415580:MTTP
uniprot id: A0A6P7WTU9
uniprot id: A0A6P7WZP1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115465822
gene id: 1415580:LOC115465822
uniprot id: A0A6P7XJ03
uniprot id: A0A6P7XP32
uniprot id: A0A6P7XP36
uniprot id: A0A6P7XPY8
names: Function
names: Subcellular Location Annotation
messages: May play a role in anchoring the cytoskeleton to the plasma membrane.
messages: cytoskeleton

1415580:RPL36A
gene id: 1415580:RPL36A
uniprot id: A0A6P7YMF0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

1415580:DKK4
gene id: 1415580:DKK4
uniprot id: A0A6P7XYG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

1415580:IPO8
gene id: 1415580:IPO8
uniprot id: A0A6P7YTB6
names: Subcellular Location Annotation
messages: Cytoplasm

1415580:LOC115464326
gene id: 1415580:LOC115464326
uniprot id: A0A6P7XIT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115471822
gene id: 1415580:LOC115471822
uniprot id: A0A6P7Y206
uniprot id: A0A6P7Y936
uniprot id: A0A6P7Y9A5
uniprot id: A0A6P7Y9A8
uniprot id: A0A6P7YEL2
uniprot id: A0A6P7YEL7
uniprot id: A0A6P7YFA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOR1AIP family.
messages: Membrane

1415580:NR0B1
gene id: 1415580:NR0B1
uniprot id: A0A6P7Y099
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus

1415580:NOTCH3
gene id: 1415580:NOTCH3
uniprot id: A0A6P7XRI3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

1415580:ENTPD7
gene id: 1415580:ENTPD7
uniprot id: A0A6P7Y7S7
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

1415580:MIF4GD
gene id: 1415580:MIF4GD
uniprot id: A0A6P7Y9J3
uniprot id: A0A6P7YGJ8
uniprot id: A0A6P7YGS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1415580:LOC115463425
gene id: 1415580:LOC115463425
uniprot id: A0A6P7XHL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115461471
gene id: 1415580:LOC115461471
uniprot id: A0A6P7X3Y0
uniprot id: A0A6P7XAJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

1415580:RGN
gene id: 1415580:RGN
uniprot id: A0A6P7XMB3
uniprot id: A0A6P7XVG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMP-30/CGR1 family.
messages: Cytoplasm

1415580:TENM4
gene id: 1415580:TENM4
uniprot id: A0A6P7XSB0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:UGDH
gene id: 1415580:UGDH
uniprot id: A0A6P7X402
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
messages: Homohexamer.
messages: Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate.

1415580:RAB5IF
gene id: 1415580:RAB5IF
uniprot id: A0A6P7YW93
uniprot id: A0A6P7YZE4
uniprot id: A0A6P7Z009
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115458165
gene id: 1415580:LOC115458165
uniprot id: A0A6P7WKL4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:SIDT2
gene id: 1415580:SIDT2
uniprot id: A0A6P7ZAR4
uniprot id: A0A6P7ZF32
uniprot id: A0A6P7ZMH5
uniprot id: A0A6P7ZT93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SID1 family.
messages: Membrane

1415580:PSMA2
gene id: 1415580:PSMA2
uniprot id: A0A6P7X5M3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

1415580:LOC115464689
gene id: 1415580:LOC115464689
uniprot id: A0A6P7XCD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.
messages: Cell membrane
messages: Membrane

1415580:GGT7
gene id: 1415580:GGT7
uniprot id: A0A6P7YWM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

1415580:STAT6
gene id: 1415580:STAT6
uniprot id: A0A6P7XH40
uniprot id: A0A6P7XPA6
uniprot id: A0A6P7XQ51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

1415580:STARD8
gene id: 1415580:STARD8
uniprot id: A0A6P7YN33
names: Subcellular Location Annotation
messages: Cytoplasm

1415580:ROCK1
gene id: 1415580:ROCK1
uniprot id: A0A6P7YVX7
uniprot id: A0A6P7YZ53
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by RHOA binding. Inhibited by Y-27632.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cytoplasm
messages: Homodimer.
messages: Membrane
messages: Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.

1415580:CALHM4
gene id: 1415580:CALHM4
uniprot id: A0A6P7XHX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

1415580:LOC115472526
gene id: 1415580:LOC115472526
uniprot id: A0A6P7YCA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Membrane

1415580:ANAPC16
gene id: 1415580:ANAPC16
uniprot id: A0A6P7Y3D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC16 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: Cytoplasm
messages: Nucleus
messages: kinetochore

1415580:LOC115471875
gene id: 1415580:LOC115471875
uniprot id: A0A6P7Y9L7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115458167
gene id: 1415580:LOC115458167
uniprot id: A0A6P7X032
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LOC115482003
gene id: 1415580:LOC115482003
uniprot id: A0A6P7ZVT4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1415580:TNN
gene id: 1415580:TNN
uniprot id: A0A6P7Y7E0
uniprot id: A0A6P7YEH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: extracellular matrix

1415580:APC2
gene id: 1415580:APC2
uniprot id: A0A6P7ZI17
names: Similarity
messages: Belongs to the adenomatous polyposis coli (APC) family.

1415580:NRXN1
gene id: 1415580:NRXN1
uniprot id: A0A6P7XER6
names: Caution
names: Similarity
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:CNOT2
gene id: 1415580:CNOT2
uniprot id: A0A6P7YRY8
uniprot id: A0A6P7YYG4
uniprot id: A0A6P7YZM8
uniprot id: A0A6P7Z3C1
names: Similarity
messages: Belongs to the CNOT2/3/5 family.

1415580:EML1
gene id: 1415580:EML1
uniprot id: A0A6P7YXY0
uniprot id: A0A6P7YZ38
uniprot id: A0A6P7Z1X4
uniprot id: A0A6P7Z2W8
names: Similarity
messages: Belongs to the WD repeat EMAP family.

1415580:LOC115460639
gene id: 1415580:LOC115460639
uniprot id: A0A6P7X6Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

1415580:DRD4
gene id: 1415580:DRD4
uniprot id: A0A6P7YYN2
uniprot id: A0A6P7Z4D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:QSOX2
gene id: 1415580:QSOX2
uniprot id: A0A6P7Y7H0
names: Function
names: Similarity
messages: Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.
messages: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide.

1415580:LOC115482394
gene id: 1415580:LOC115482394
uniprot id: A0A6P7ZVC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

1415580:FAM189A1
gene id: 1415580:FAM189A1
uniprot id: A0A6P7X2Q5
names: Similarity
messages: Belongs to the ENTREP family.

1415580:KCNQ4
gene id: 1415580:KCNQ4
uniprot id: A0A6P7Z1V0
uniprot id: A0A6P7ZCH1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:KCNG4
gene id: 1415580:KCNG4
uniprot id: A0A6P7Y096
names: Subcellular Location Annotation
messages: Membrane

1415580:CENPO
gene id: 1415580:CENPO
uniprot id: A0A6P7XPS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-O/MCM21 family.
messages: Nucleus

1415580:LOC115467935
gene id: 1415580:LOC115467935
uniprot id: A0A6P7XX90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEN-2 family.
messages: Golgi stack membrane
messages: Membrane

1415580:ADGRG2
gene id: 1415580:ADGRG2
uniprot id: A0A6P7XZ19
uniprot id: A0A6P7Y001
uniprot id: A0A6P7Y007
uniprot id: A0A6P7Y4V4
uniprot id: A0A6P7Y5W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

1415580:LOC115457046
gene id: 1415580:LOC115457046
uniprot id: A0A6P7WVQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115482552
gene id: 1415580:LOC115482552
uniprot id: A0A6P7ZMT6
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115457867
gene id: 1415580:LOC115457867
uniprot id: A0A6P7WQI3
names: Similarity
messages: Belongs to the ARTD/PARP family.

1415580:REV1
gene id: 1415580:REV1
uniprot id: A0A6P7XWD8
uniprot id: A0A6P7XXL5
uniprot id: A0A6P7Y355
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-Y family.
messages: Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
messages: Nucleus

1415580:LOC115475957
gene id: 1415580:LOC115475957
uniprot id: A0A6P7YT74
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115460279
gene id: 1415580:LOC115460279
uniprot id: A0A6P7X6Y2
names: Similarity
messages: Belongs to the FAM20 family.

1415580:TMEM116
gene id: 1415580:TMEM116
uniprot id: A0A6P7Z8D1
uniprot id: A0A6P7ZD10
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115481182
gene id: 1415580:LOC115481182
uniprot id: A0A6P7Z9V8
uniprot id: A0A6P7ZE91
uniprot id: A0A6P7ZKB5
uniprot id: A0A6P7ZNX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

1415580:TMEM134
gene id: 1415580:TMEM134
uniprot id: A0A6P7WV84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Membrane

1415580:TSPAN6
gene id: 1415580:TSPAN6
uniprot id: A0A6P7YKW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

1415580:MLF2
gene id: 1415580:MLF2
uniprot id: A0A6P7WLR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLF family.
messages: Cytoplasm

1415580:LOC115475049
gene id: 1415580:LOC115475049
uniprot id: A0A6P7YGT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:FAM187A
gene id: 1415580:FAM187A
uniprot id: A0A6P7ZQ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM187 family.
messages: Membrane

1415580:LOC115478127
gene id: 1415580:LOC115478127
uniprot id: A0A6P7Z680
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

1415580:LOC115464448
gene id: 1415580:LOC115464448
uniprot id: A0A6P7X505
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:MYO1A
gene id: 1415580:MYO1A
uniprot id: A0A6P7XPB1
uniprot id: A0A6P7XQ54
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

1415580:ELAVL2
gene id: 1415580:ELAVL2
uniprot id: A0A6P7X364
uniprot id: A0A6P7X9N7
uniprot id: A0A6P7XBY4
uniprot id: A0A6P7XBY7
uniprot id: A0A6P7XH76
names: Similarity
messages: Belongs to the RRM elav family.

1415580:BMS1
gene id: 1415580:BMS1
uniprot id: A0A6P7XUG7
uniprot id: A0A6P7Y2P3
names: Subcellular Location Annotation
messages: nucleolus

1415580:LOC115474637
gene id: 1415580:LOC115474637
uniprot id: A0A6P7YM35
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

1415580:MYH10
gene id: 1415580:MYH10
uniprot id: A0A6P7Y911
uniprot id: A0A6P7YG10
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

1415580:STAT4
gene id: 1415580:STAT4
uniprot id: A0A6P7YS96
uniprot id: A0A6P7YSE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

1415580:LOC115457186
gene id: 1415580:LOC115457186
uniprot id: A0A6P7WN44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:RAD9A
gene id: 1415580:RAD9A
uniprot id: A0A6P7WKQ8
uniprot id: A0A6P7WTP2
names: Similarity
messages: Belongs to the rad9 family.

1415580:PDE1C
gene id: 1415580:PDE1C
uniprot id: A0A6P7YBK4
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

1415580:LOC115461944
gene id: 1415580:LOC115461944
uniprot id: A0A6P7XBB6
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115457145
gene id: 1415580:LOC115457145
uniprot id: A0A6P7WPX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115481696
gene id: 1415580:LOC115481696
uniprot id: A0A6P7ZPX0
names: Similarity
messages: Belongs to the ARTD/PARP family.

1415580:LOC115462510
gene id: 1415580:LOC115462510
uniprot id: A0A6P7X7F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

1415580:ILDR1
gene id: 1415580:ILDR1
uniprot id: A0A6P7XWM1
uniprot id: A0A6P7Y4L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

1415580:HIF1A
gene id: 1415580:HIF1A
uniprot id: A0A6P7Z3G6
names: Subcellular Location Annotation
messages: Cytoplasm

1415580:ANK2
gene id: 1415580:ANK2
uniprot id: A0A6P7WU53
uniprot id: A0A6P7WZX8
uniprot id: A0A6P7WZY3
uniprot id: A0A6P7X2K9
uniprot id: A0A6P7X2L6
uniprot id: A0A6P7X7Z6
uniprot id: A0A6P7X9B8
uniprot id: A0A6P7X9C3
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

1415580:SMARCD2
gene id: 1415580:SMARCD2
uniprot id: A0A6P7ZW70
names: Similarity
messages: Belongs to the SMARCD family.

1415580:LOC115470569
gene id: 1415580:LOC115470569
uniprot id: A0A6P7XW79
uniprot id: A0A6P7Y471
names: Similarity
messages: Belongs to the SH3BGR family.

1415580:LOC115460183
gene id: 1415580:LOC115460183
uniprot id: A0A6P7WXK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ferritin family.
messages: Oligomer of 24 subunits. The functional molecule is roughly spherical and contains a central cavity into which the polymeric mineral iron core is deposited.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

1415580:LOC115456988
gene id: 1415580:LOC115456988
uniprot id: A0A6P7WVH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

1415580:LOC115457883
gene id: 1415580:LOC115457883
uniprot id: A0A6P7WYP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115482541
gene id: 1415580:LOC115482541
uniprot id: A0A6P7ZG01
names: Similarity
messages: Belongs to the peptidase C1 family.

1415580:DIO1
gene id: 1415580:DIO1
uniprot id: A0A6P7Y9V3
names: Function
names: Similarity
messages: Belongs to the iodothyronine deiodinase family.
messages: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).

1415580:PDIA6
gene id: 1415580:PDIA6
uniprot id: A0A6P7XQA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Melanosome

1415580:KIF7
gene id: 1415580:KIF7
uniprot id: A0A6P7Y381
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

1415580:GPR108
gene id: 1415580:GPR108
uniprot id: A0A6P7XAX7
uniprot id: A0A6P7XJS0
names: Subcellular Location Annotation
messages: Membrane

1415580:TMEM87A
gene id: 1415580:TMEM87A
uniprot id: A0A6P7Z4F9
names: Subcellular Location Annotation
messages: Membrane

1415580:NQO1
gene id: 1415580:NQO1
uniprot id: A0A6P7Y6B7
names: Similarity
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family.

1415580:GRID1
gene id: 1415580:GRID1
uniprot id: A0A6P7Y314
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

1415580:TRMT1
gene id: 1415580:TRMT1
uniprot id: A0A6P7XHX4
uniprot id: A0A6P7XQ33
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.

1415580:ATXN3
gene id: 1415580:ATXN3
uniprot id: A0A6P7YYQ6
names: Subcellular Location Annotation
messages: Nucleus

1415580:RNF31
gene id: 1415580:RNF31
uniprot id: A0A6P7WIN5
uniprot id: A0A6P7WS04
names: Similarity
messages: Belongs to the RBR family.

1415580:AP2A2
gene id: 1415580:AP2A2
uniprot id: A0A6P7XX51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit AP2A1 or AP2A2 and beta-type subunit AP2B1), a medium adaptin (mu-type subunit AP2M1) and a small adaptin (sigma-type subunit AP2S1).
messages: Belongs to the adaptor complexes large subunit family.
messages: Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules. AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway. The AP-2 alpha subunit binds polyphosphoinositide-containing lipids, positioning AP-2 on the membrane. The AP-2 alpha subunit acts via its C-terminal appendage domain as a scaffolding platform for endocytic accessory proteins. The AP-2 alpha and AP-2 sigma subunits are thought to contribute to the recognition of the [ED]-X-X-X-L-[LI] motif.
messages: coated pit

1415580:PAPPA
gene id: 1415580:PAPPA
uniprot id: A0A6P7YED4
names: Caution
names: Similarity
messages: Belongs to the peptidase M43B family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115480888
gene id: 1415580:LOC115480888
uniprot id: A0A6P7ZD92
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1415580:CPT1C
gene id: 1415580:CPT1C
uniprot id: A0A6P7XMQ9
uniprot id: A0A6P7XTR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

1415580:GPR137
gene id: 1415580:GPR137
uniprot id: A0A6P7Z9F4
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

1415580:LOC115472401
gene id: 1415580:LOC115472401
uniprot id: A0A6P7Y4T6
names: Similarity
messages: Belongs to the avidin/streptavidin family.

1415580:LACTB2
gene id: 1415580:LACTB2
uniprot id: A0A6P7YVV7
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.

1415580:NUBP1
gene id: 1415580:NUBP1
uniprot id: A0A6P7YHK7
uniprot id: A0A6P7YQB7
uniprot id: A0A6P7YUI4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.
messages: Cell projection
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
messages: Cytoplasm
messages: Heterotetramer of 2 NUBP1 and 2 NUBP2 chains.

1415580:NUP62CL
gene id: 1415580:NUP62CL
uniprot id: A0A6P7YF69
names: Similarity
messages: Belongs to the nucleoporin NSP1/NUP62 family.

1415580:UHRF2
gene id: 1415580:UHRF2
uniprot id: A0A6P7X249
uniprot id: A0A6P7X8I6
uniprot id: A0A6P7XAX1
uniprot id: A0A6P7XH91
names: Subcellular Location Annotation
messages: Nucleus

1415580:FEN1
gene id: 1415580:FEN1
uniprot id: A0A6P7XVM9
uniprot id: A0A6P7Y2G3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. Three molecules of FEN1 bind to one PCNA trimer with each molecule binding to one PCNA monomer. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Mitochondrion
messages: Phosphorylated. Phosphorylation upon DNA damage induces relocalization to the nuclear plasma.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
messages: nucleolus
messages: nucleoplasm

1415580:OTOG
gene id: 1415580:OTOG
uniprot id: A0A6P7XZJ9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115478660
gene id: 1415580:LOC115478660
uniprot id: A0A6P7Z3Q9
names: Similarity
messages: Belongs to the peptidase M14 family.

1415580:TATDN2
gene id: 1415580:TATDN2
uniprot id: A0A6P7YH98
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1415580:MEMO1
gene id: 1415580:MEMO1
uniprot id: A0A6P7XN27
names: Similarity
messages: Belongs to the MEMO1 family.

1415580:WNT1
gene id: 1415580:WNT1
uniprot id: A0A6P7XCZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

1415580:LOC115477798
gene id: 1415580:LOC115477798
uniprot id: A0A6P7Z5L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
messages: axon

1415580:LOC115482440
gene id: 1415580:LOC115482440
uniprot id: A0A6P7ZLG1
names: Similarity
messages: Belongs to the EXO5 family.

1415580:VIPR2
gene id: 1415580:VIPR2
uniprot id: A0A6P7XQ22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115456994
gene id: 1415580:LOC115456994
uniprot id: A0A6P7WGB7
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Membrane
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

1415580:LOC115471581
gene id: 1415580:LOC115471581
uniprot id: A0A6P7YE65
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:RPL35
gene id: 1415580:RPL35
uniprot id: A0A6P7Y6U8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1415580:LOC115467335
gene id: 1415580:LOC115467335
uniprot id: A0A6P7XHU4
uniprot id: A0A6P7XPJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

1415580:CDKN1B
gene id: 1415580:CDKN1B
uniprot id: A0A6P7Z3S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDI family.
messages: Cytoplasm
messages: Endosome
messages: Nucleus

1415580:LOC115472562
gene id: 1415580:LOC115472562
uniprot id: A0A6P7YIH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

1415580:LOC115480389
gene id: 1415580:LOC115480389
uniprot id: A0A6P7ZHK6
uniprot id: A0A6P7ZIK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAUG family.
messages: Cytoplasm

1415580:CD8B
gene id: 1415580:CD8B
uniprot id: A0A6P7X547
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115461013
gene id: 1415580:LOC115461013
uniprot id: A0A6P7WZ22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:OLFM1
gene id: 1415580:OLFM1
uniprot id: A0A6P7Y7K9
uniprot id: A0A6P7YF00
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

1415580:TP73
gene id: 1415580:TP73
uniprot id: A0A6P7WMZ3
uniprot id: A0A6P7WV04
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer.
messages: Cytoplasm
messages: Nucleus

1415580:TCEA1
gene id: 1415580:TCEA1
uniprot id: A0A6P7YZC9
uniprot id: A0A6P7Z0I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

1415580:LOC115473126
gene id: 1415580:LOC115473126
uniprot id: A0A6P7YF41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1415580:CALHM6
gene id: 1415580:CALHM6
uniprot id: A0A6P7XL58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

1415580:SS18
gene id: 1415580:SS18
uniprot id: A0A6P7YYB8
uniprot id: A0A6P7Z245
names: Similarity
messages: Belongs to the SS18 family.

1415580:LOC115478659
gene id: 1415580:LOC115478659
uniprot id: A0A6P7YY13
uniprot id: A0A6P7YY18
uniprot id: A0A6P7Z3Q4
uniprot id: A0A6P7Z5W1
uniprot id: A0A6P7Z5W5
uniprot id: A0A6P7Z8J6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:TAF1B
gene id: 1415580:TAF1B
uniprot id: A0A6P7XNN6
uniprot id: A0A6P7XVN8
uniprot id: A0A6P7XW86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRN7/TAF1B family.
messages: nucleolus

1415580:FAM47E
gene id: 1415580:FAM47E
uniprot id: A0A6P7XCL6
names: Similarity
messages: Belongs to the FAM47 family.

1415580:LOC115464834
gene id: 1415580:LOC115464834
uniprot id: A0A6P7XEZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

1415580:NRDE2
gene id: 1415580:NRDE2
uniprot id: A0A6P7Z4D7
names: Similarity
messages: Belongs to the NRDE2 family.

1415580:PLPP3
gene id: 1415580:PLPP3
uniprot id: A0A6P7Y3P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

1415580:LOC115481350
gene id: 1415580:LOC115481350
uniprot id: A0A6P7ZAD1
names: Similarity
messages: Belongs to the TMEM106 family.

1415580:OPRK1
gene id: 1415580:OPRK1
uniprot id: A0A6P7WS46
uniprot id: A0A6P7X0I3
uniprot id: A0A6P7X737
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain. Plays a role in mediating reduced physical activity upon treatment with synthetic opioids. Plays a role in the regulation of salivation in response to synthetic opioids. May play a role in arousal and regulation of autonomic and neuroendocrine functions.
messages: Interacts with SLC9A3R1. Interacts with GABARAPL1.
messages: Membrane

1415580:LOC115480031
gene id: 1415580:LOC115480031
uniprot id: A0A6P7X5J9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1415580:LOC115479148
gene id: 1415580:LOC115479148
uniprot id: A0A6P7Z0C1
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

1415580:ATP6V1B1
gene id: 1415580:ATP6V1B1
uniprot id: A0A6P7XCS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.

1415580:MYOZ1
gene id: 1415580:MYOZ1
uniprot id: A0A6P7Y299
names: Similarity
messages: Belongs to the myozenin family.

1415580:LOC115472807
gene id: 1415580:LOC115472807
uniprot id: A0A6P7Y6F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Cytoplasm
messages: Nucleus
messages: Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.

1415580:LOC115457238
gene id: 1415580:LOC115457238
uniprot id: A0A6P7WX79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:PRKCA
gene id: 1415580:PRKCA
uniprot id: A0A6P7YH95
uniprot id: A0A6P7YMF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm
messages: Membrane

1415580:LOC115463464
gene id: 1415580:LOC115463464
uniprot id: A0A6P7X2Q1
uniprot id: A0A6P7X956
names: Function
names: Subcellular Location Annotation
messages: Acts as guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases.
messages: Cytoplasm

1415580:E2F4
gene id: 1415580:E2F4
uniprot id: A0A6P7XVY1
uniprot id: A0A6P7Y384
uniprot id: A0A6P7Y3Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

1415580:LOC115457088
gene id: 1415580:LOC115457088
uniprot id: A0A6P7WGK3
names: Subcellular Location Annotation
messages: Membrane

1415580:SLC25A27
gene id: 1415580:SLC25A27
uniprot id: A0A6P7XGJ6
uniprot id: A0A6P7XND8
uniprot id: A0A6P7XVE2
uniprot id: A0A6P7XVY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1415580:LOC115472409
gene id: 1415580:LOC115472409
uniprot id: A0A6P7YHN3
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

1415580:LOC115479030
gene id: 1415580:LOC115479030
uniprot id: A0A6P7Z5A5
names: Similarity
messages: Belongs to the GSK-3-binding protein family.

1415580:KCNK5
gene id: 1415580:KCNK5
uniprot id: A0A6P7XGN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

1415580:LOC115472469
gene id: 1415580:LOC115472469
uniprot id: A0A6P7YI80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the VHL family.
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
messages: Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.
messages: Interacts with MYD88. IL-1 stimulation leads to the formation of a signaling complex which dissociates from the IL-1 receptor following the binding of PELI1.

1415580:USP30
gene id: 1415580:USP30
uniprot id: A0A6P7ZBR9
names: Similarity
messages: Belongs to the peptidase C19 family.

1415580:LOC115457786
gene id: 1415580:LOC115457786
uniprot id: A0A6P7WY79
names: Subcellular Location Annotation
messages: Membrane

1415580:ZNRD1
gene id: 1415580:ZNRD1
uniprot id: A0A6P7XKQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase I (Pol I) complex consisting of at least 13 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors.
messages: nucleolus

1415580:FAM229A
gene id: 1415580:FAM229A
uniprot id: A0A6P7Z834
names: Similarity
messages: Belongs to the FAM229 family.

1415580:ANKZF1
gene id: 1415580:ANKZF1
uniprot id: A0A6P7YEL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKZF1/VMS1 family.
messages: Cytoplasm

1415580:LOC115473929
gene id: 1415580:LOC115473929
uniprot id: A0A6P7YP51
names: Similarity
messages: Belongs to the serpin family.

1415580:LOC115480172
gene id: 1415580:LOC115480172
uniprot id: A0A6P7ZAC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVBP family.
messages: Secreted
messages: cytoskeleton

1415580:C8H16orf72
gene id: 1415580:C8H16orf72
uniprot id: A0A6P7YXV8
names: Similarity
messages: Belongs to the TAPR1 family.

1415580:PDCD4
gene id: 1415580:PDCD4
uniprot id: A0A6P7XT69
uniprot id: A0A6P7Y682
uniprot id: A0A6P7Y7B2
names: Similarity
messages: Belongs to the PDCD4 family.

1415580:ZIC1
gene id: 1415580:ZIC1
uniprot id: A0A6P7Z6Q9
uniprot id: A0A6P7ZA44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

1415580:PRR15
gene id: 1415580:PRR15
uniprot id: A0A6P7WRM0
names: Similarity
messages: Belongs to the PRR15 family.

1415580:LOC115462392
gene id: 1415580:LOC115462392
uniprot id: A0A6P7XCD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB11 subunit family.
messages: Membrane

1415580:SLC9A3R2
gene id: 1415580:SLC9A3R2
uniprot id: A0A6P7YVB3
names: Function
names: Subcellular Location Annotation
messages: Endomembrane system
messages: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.

1415580:EPHA7
gene id: 1415580:EPHA7
uniprot id: A0A6P7XW73
uniprot id: A0A6P7XWW1
names: Subcellular Location Annotation
messages: Membrane

1415580:KCNN4
gene id: 1415580:KCNN4
uniprot id: A0A6P7YW16
uniprot id: A0A6P7YW89
names: Subcellular Location Annotation
messages: Membrane

1415580:APLP2
gene id: 1415580:APLP2
uniprot id: A0A6P7ZDN1
uniprot id: A0A6P7ZTJ6
uniprot id: A0A6P7ZV59
uniprot id: A0A6P7ZVY0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:SLC25A38
gene id: 1415580:SLC25A38
uniprot id: A0A6P7YCV7
uniprot id: A0A6P7YI59
uniprot id: A0A6P7YIK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
messages: Membrane
messages: Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis.
messages: Mitochondrion inner membrane

1415580:LOC115472886
gene id: 1415580:LOC115472886
uniprot id: A0A6P7YJU0
names: Subcellular Location Annotation
messages: ruffle membrane

1415580:KHDRBS3
gene id: 1415580:KHDRBS3
uniprot id: A0A6P7Z7L9
names: Similarity
messages: Belongs to the KHDRBS family.

1415580:CCDC47
gene id: 1415580:CCDC47
uniprot id: A0A6P7ZTC6
names: Subcellular Location Annotation
messages: Membrane
messages: Rough endoplasmic reticulum membrane

1415580:LOC115474477
gene id: 1415580:LOC115474477
uniprot id: A0A6P7YLE4
names: Similarity
messages: Belongs to the cytochrome P450 family.

1415580:IRF4
gene id: 1415580:IRF4
uniprot id: A0A6P7X0A9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

1415580:LOC115482348
gene id: 1415580:LOC115482348
uniprot id: A0A6P7ZF40
uniprot id: A0A6P7ZV84
uniprot id: A0A6P7ZVU4
names: Similarity
messages: Belongs to the MS4A family.

1415580:BBS4
gene id: 1415580:BBS4
uniprot id: A0A6P7WJG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBS4 family.
messages: Membrane
messages: centrosome
messages: cilium membrane

1415580:ZFYVE16
gene id: 1415580:ZFYVE16
uniprot id: A0A6P7X7B3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Early endosome membrane

1415580:IRX5
gene id: 1415580:IRX5
uniprot id: A0A6P7Y7Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

1415580:CDH19
gene id: 1415580:CDH19
uniprot id: A0A6P7YYW7
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

1415580:MFAP5
gene id: 1415580:MFAP5
uniprot id: A0A6P7WII4
uniprot id: A0A6P7WRU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MFAP family.
messages: extracellular matrix

1415580:TUT4
gene id: 1415580:TUT4
uniprot id: A0A6P7Y1A9
uniprot id: A0A6P7Y8J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B-like family.
messages: Cytoplasm

1415580:TMA16
gene id: 1415580:TMA16
uniprot id: A0A6P7X7W1
names: Function
names: Similarity
names: Subunit
messages: Associates with pre-60S ribosomal particles.
messages: Belongs to the TMA16 family.
messages: Involved in the biogenesis of the 60S ribosomal subunit in the nucleus.

1415580:SLC35F2
gene id: 1415580:SLC35F2
uniprot id: A0A6P7XZC9
uniprot id: A0A6P7Y000
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

1415580:LOC115473429
gene id: 1415580:LOC115473429
uniprot id: A0A6P7YH01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

1415580:LOC115456712
gene id: 1415580:LOC115456712
uniprot id: A0A6P7WF71
uniprot id: A0A6P7WLD6
uniprot id: A0A6P7WNA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

1415580:CFDP1
gene id: 1415580:CFDP1
uniprot id: A0A6P7Y3U4
names: Function
names: Subcellular Location Annotation
messages: May play a role during embryogenesis.
messages: kinetochore

1415580:SLC29A2
gene id: 1415580:SLC29A2
uniprot id: A0A6P7ZFA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

1415580:LOC115464411
gene id: 1415580:LOC115464411
uniprot id: A0A6P7X4W8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:NR2F2
gene id: 1415580:NR2F2
uniprot id: A0A6P7WQV0
uniprot id: A0A6P7WZC1
uniprot id: A0A6P7X4U2
uniprot id: A0A6P7X616
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

1415580:UBR1
gene id: 1415580:UBR1
uniprot id: A0A6P7Z6M7
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

1415580:LIN7A
gene id: 1415580:LIN7A
uniprot id: A0A6P7Z3N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-7 family.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.

1415580:GAREM1
gene id: 1415580:GAREM1
uniprot id: A0A6P7YXX5
names: Similarity
messages: Belongs to the GAREM family.

1415580:RFLNB
gene id: 1415580:RFLNB
uniprot id: A0A6P7WL54
uniprot id: A0A6P7WU39
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Refilin family.
messages: Interacts with FLNA and FLNB.
messages: cytoskeleton

1415580:PRKAR2A
gene id: 1415580:PRKAR2A
uniprot id: A0A6P7YG97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

1415580:CTSC
gene id: 1415580:CTSC
uniprot id: A0A6P7XZR0
names: Similarity
names: Subunit
messages: Belongs to the peptidase C1 family.
messages: Tetramer of heterotrimers consisting of exclusion domain, heavy- and light chains.

1415580:LOC115472920
gene id: 1415580:LOC115472920
uniprot id: A0A6P7YE37
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LSM14A
gene id: 1415580:LSM14A
uniprot id: A0A6P7YB81
names: Similarity
messages: Belongs to the LSM14 family.

1415580:LOC115458183
gene id: 1415580:LOC115458183
uniprot id: A0A6P7X179
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LOC115457714
gene id: 1415580:LOC115457714
uniprot id: A0A6P7WIK4
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115473983
gene id: 1415580:LOC115473983
uniprot id: A0A6P7YPC8
names: Similarity
messages: Belongs to the cytochrome P450 family.

1415580:POLR2K
gene id: 1415580:POLR2K
uniprot id: A0A6P7ZCM6
names: Similarity
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.

1415580:LOC115461994
gene id: 1415580:LOC115461994
uniprot id: A0A6P7WXF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:DSCC1
gene id: 1415580:DSCC1
uniprot id: A0A6P7Z4X4
names: Similarity
messages: Belongs to the DCC1 family.

1415580:KIFC3
gene id: 1415580:KIFC3
uniprot id: A0A6P7XVD7
uniprot id: A0A6P7Y3K2
uniprot id: A0A6P7Y8J1
uniprot id: A0A6P7Y9D2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

1415580:LOC115464287
gene id: 1415580:LOC115464287
uniprot id: A0A6P7XIP7
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

1415580:RALYL
gene id: 1415580:RALYL
uniprot id: A0A6P7Z8Z1
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

1415580:LOC115468523
gene id: 1415580:LOC115468523
uniprot id: A0A6P7XUH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1415580:PPARA
gene id: 1415580:PPARA
uniprot id: A0A6P7Z1G8
uniprot id: A0A6P7Z1H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

1415580:LOC115457037
gene id: 1415580:LOC115457037
uniprot id: A0A6P7WWN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:TET3
gene id: 1415580:TET3
uniprot id: A0A6P7XXH5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TET family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Chromosome
messages: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development.
messages: The zinc ions have a structural role.

1415580:ZIC2
gene id: 1415580:ZIC2
uniprot id: A0A6P7XQK9
uniprot id: A0A6P7XSA3
uniprot id: A0A6P7XXF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

1415580:SMIM12
gene id: 1415580:SMIM12
uniprot id: A0A6P7Z435
names: Similarity
messages: Belongs to the SMIM12 family.

1415580:ALDH5A1
gene id: 1415580:ALDH5A1
uniprot id: A0A6P7YQS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).
messages: Homotetramer.
messages: Mitochondrion

1415580:LOC115464627
gene id: 1415580:LOC115464627
uniprot id: A0A6P7XC82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:RFX3
gene id: 1415580:RFX3
uniprot id: A0A6P7X8L9
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115457398
gene id: 1415580:LOC115457398
uniprot id: A0A6P7WNN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115464413
gene id: 1415580:LOC115464413
uniprot id: A0A6P7XK16
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LOC115477527
gene id: 1415580:LOC115477527
uniprot id: A0A6P7YZE7
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1415580:WNT16
gene id: 1415580:WNT16
uniprot id: A0A6P7Z641
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

1415580:EDIL3
gene id: 1415580:EDIL3
uniprot id: A0A6P7X9P2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115474257
gene id: 1415580:LOC115474257
uniprot id: A0A6P7YKJ1
names: Similarity
messages: Belongs to the SUA5 family.

1415580:NBL1
gene id: 1415580:NBL1
uniprot id: A0A6P7WTY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

1415580:ARSA
gene id: 1415580:ARSA
uniprot id: A0A6P7YZJ4
uniprot id: A0A6P7Z7D3
uniprot id: A0A6P7ZA18
uniprot id: A0A6P7ZAV6
uniprot id: A0A6P7ZAW0
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1415580:LHFPL2
gene id: 1415580:LHFPL2
uniprot id: A0A6P7X9C4
names: Subcellular Location Annotation
messages: Membrane

1415580:P2RY14
gene id: 1415580:P2RY14
uniprot id: A0A6P7YZN4
uniprot id: A0A6P7Z7G9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:IMMT
gene id: 1415580:IMMT
uniprot id: A0A6P7WUT4
uniprot id: A0A6P7X0M3
uniprot id: A0A6P7X386
uniprot id: A0A6P7X8N5
uniprot id: A0A6P7X9X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic60 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

1415580:DYRK4
gene id: 1415580:DYRK4
uniprot id: A0A6P7YU15
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

1415580:SARAF
gene id: 1415580:SARAF
uniprot id: A0A6P7XAN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SARAF family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:RPRM
gene id: 1415580:RPRM
uniprot id: A0A6P7YL88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reprimo family.
messages: Cytoplasm
messages: Membrane

1415580:LOC115472218
gene id: 1415580:LOC115472218
uniprot id: A0A6P7Y423
uniprot id: A0A6P7YB58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGA family.
messages: Nucleus

1415580:RPS24
gene id: 1415580:RPS24
uniprot id: A0A6P7Y2N1
uniprot id: A0A6P7Y8H3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

1415580:TSG101
gene id: 1415580:TSG101
uniprot id: A0A6P7Y6D3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.

1415580:SART1
gene id: 1415580:SART1
uniprot id: A0A6P7ZHU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNU66/SART1 family.
messages: Nucleus

1415580:HOOK1
gene id: 1415580:HOOK1
uniprot id: A0A6P7YAK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hook family.
messages: cytoskeleton

1415580:RBPJ
gene id: 1415580:RBPJ
uniprot id: A0A6P7X171
uniprot id: A0A6P7X975
uniprot id: A0A6P7XAG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Su(H) family.
messages: Nucleus

1415580:LOC115462877
gene id: 1415580:LOC115462877
uniprot id: A0A6P7WZT9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1415580:LOC115478596
gene id: 1415580:LOC115478596
uniprot id: A0A6P7Z933
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115478976
gene id: 1415580:LOC115478976
uniprot id: A0A6P7Z531
uniprot id: A0A6P7ZA09
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

1415580:TLR9
gene id: 1415580:TLR9
uniprot id: A0A6P7YCH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Endosome
messages: Membrane

1415580:NHS
gene id: 1415580:NHS
uniprot id: A0A6P7XZ36
names: Similarity
messages: Belongs to the NHS family.

1415580:MEA1
gene id: 1415580:MEA1
uniprot id: A0A6P7XEA9
names: Function
messages: May play an important role in spermatogenesis and/or testis development.

1415580:GDPD3
gene id: 1415580:GDPD3
uniprot id: A0A6P7YLP8
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

1415580:FAM92B
gene id: 1415580:FAM92B
uniprot id: A0A6P7XT12
uniprot id: A0A6P7Y159
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CIBAR family.
messages: centriole

1415580:WDR24
gene id: 1415580:WDR24
uniprot id: A0A6P7YYL5
names: Similarity
messages: Belongs to the WD repeat WDR24 family.

1415580:RNPS1
gene id: 1415580:RNPS1
uniprot id: A0A6P7YLD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Nucleus speckle

1415580:SLC35F6
gene id: 1415580:SLC35F6
uniprot id: A0A6P7XN22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLC35F solute transporter family.
messages: Interacts with SLC25A5.
messages: May play a role as a nucleotide-sugar transporter.
messages: Membrane
messages: Mitochondrion

1415580:GPRC6A
gene id: 1415580:GPRC6A
uniprot id: A0A6P7XFZ1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:HS2ST1
gene id: 1415580:HS2ST1
uniprot id: A0A6P7Y8B9
uniprot id: A0A6P7YDS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Membrane

1415580:LOC115463315
gene id: 1415580:LOC115463315
uniprot id: A0A6P7XAQ8
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

1415580:CHST11
gene id: 1415580:CHST11
uniprot id: A0A6P7YUR8
uniprot id: A0A6P7Z2H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

1415580:TAFA1
gene id: 1415580:TAFA1
uniprot id: A0A6P7Y8C0
names: Similarity
messages: Belongs to the TAFA family.

1415580:LOC115457879
gene id: 1415580:LOC115457879
uniprot id: A0A6P7WYN4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Secreted

1415580:SENP6
gene id: 1415580:SENP6
uniprot id: A0A6P7XWR6
names: Similarity
messages: Belongs to the peptidase C48 family.

1415580:POU6F2
gene id: 1415580:POU6F2
uniprot id: A0A6P7X047
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

1415580:LOC115466930
gene id: 1415580:LOC115466930
uniprot id: A0A6P7XUN8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

1415580:ZIC5
gene id: 1415580:ZIC5
uniprot id: A0A6P7XY61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

1415580:LOC115472269
gene id: 1415580:LOC115472269
uniprot id: A0A6P7YHH5
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115481141
gene id: 1415580:LOC115481141
uniprot id: A0A6P7ZE26
uniprot id: A0A6P7ZNN8
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115471013
gene id: 1415580:LOC115471013
uniprot id: A0A6P7Y6G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

1415580:PARN
gene id: 1415580:PARN
uniprot id: A0A6P7YUE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Cytoplasm
messages: Nucleus

1415580:BAX
gene id: 1415580:BAX
uniprot id: A0A6P7XT53
names: Similarity
messages: Belongs to the Bcl-2 family.

1415580:LOC115475582
gene id: 1415580:LOC115475582
uniprot id: A0A6P7YVG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

1415580:INSR
gene id: 1415580:INSR
uniprot id: A0A6P7ZGA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

1415580:PTPN1
gene id: 1415580:PTPN1
uniprot id: A0A6P7YQB1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

1415580:ABCB11
gene id: 1415580:ABCB11
uniprot id: A0A6P7YDV5
names: Subcellular Location Annotation
messages: Endosome

1415580:LHFPL3
gene id: 1415580:LHFPL3
uniprot id: A0A6P7Z9C2
names: Subcellular Location Annotation
messages: Membrane

1415580:CAMK4
gene id: 1415580:CAMK4
uniprot id: A0A6P7XFA7
names: Similarity
messages: Belongs to the protein kinase superfamily.

1415580:DIPK1A
gene id: 1415580:DIPK1A
uniprot id: A0A6P7YA14
uniprot id: A0A6P7YG83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Endoplasmic reticulum membrane

1415580:KCTD13
gene id: 1415580:KCTD13
uniprot id: A0A6P7YPX0
names: Similarity
messages: Belongs to the BACURD family.

1415580:TMC6
gene id: 1415580:TMC6
uniprot id: A0A6P7YN99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

1415580:AFF1
gene id: 1415580:AFF1
uniprot id: A0A6P7WTI0
uniprot id: A0A6P7WZB4
uniprot id: A0A6P7X1W9
names: Similarity
messages: Belongs to the AF4 family.

1415580:LOC115479495
gene id: 1415580:LOC115479495
uniprot id: A0A6P7ZCB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat HIR1 family.
messages: Nucleus
messages: Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

1415580:KIFC2
gene id: 1415580:KIFC2
uniprot id: A0A6P7X6A0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

1415580:DENND6B
gene id: 1415580:DENND6B
uniprot id: A0A6P7YZ45
uniprot id: A0A6P7Z4U3
uniprot id: A0A6P7Z9M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND6 family.
messages: Endosome
messages: Recycling endosome

1415580:LOC115457054
gene id: 1415580:LOC115457054
uniprot id: A0A6P7WGG9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:TNPO2
gene id: 1415580:TNPO2
uniprot id: A0A6P7XHX9
names: Subcellular Location Annotation
messages: Cytoplasm

1415580:LOC115462565
gene id: 1415580:LOC115462565
uniprot id: A0A6P7XE04
names: Similarity
messages: Belongs to the vasopressin/oxytocin family.

1415580:CNGA2
gene id: 1415580:CNGA2
uniprot id: A0A6P7YTK0
names: Subcellular Location Annotation
messages: Membrane

1415580:LDLRAD4
gene id: 1415580:LDLRAD4
uniprot id: A0A6P7YTT0
uniprot id: A0A6P7YTT6
uniprot id: A0A6P7YY01
uniprot id: A0A6P7YYN4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMEPA1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:PYGB
gene id: 1415580:PYGB
uniprot id: A0A6P7XG14
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

1415580:LOC115478498
gene id: 1415580:LOC115478498
uniprot id: A0A6P7YXA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

1415580:LOC115457652
gene id: 1415580:LOC115457652
uniprot id: A0A6P7WRM7
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

1415580:DNA2
gene id: 1415580:DNA2
uniprot id: A0A6P7XU64
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Key enzyme involved in DNA replication and DNA repair. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA.
messages: Mitochondrion
messages: Nucleus

1415580:GATA3
gene id: 1415580:GATA3
uniprot id: A0A6P7Z5N7
uniprot id: A0A6P7ZAT1
uniprot id: A0A6P7ZBJ4
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115457275
gene id: 1415580:LOC115457275
uniprot id: A0A6P7WXB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:PRKAG1
gene id: 1415580:PRKAG1
uniprot id: A0A6P7XPR3
names: Similarity
names: Subunit
messages: AMPK is a heterotrimer of an alpha catalytic subunit (PRKAA1 or PRKAA2), a beta (PRKAB1 or PRKAB2) and a gamma non-catalytic subunits (PRKAG1, PRKAG2 or PRKAG3). Interacts with FNIP1 and FNIP2.
messages: Belongs to the 5'-AMP-activated protein kinase gamma subunit family.

1415580:LOC115457787
gene id: 1415580:LOC115457787
uniprot id: A0A6P7WQ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

1415580:SVOP
gene id: 1415580:SVOP
uniprot id: A0A6P7Z6X4
uniprot id: A0A6P7ZF96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

1415580:GDAP1
gene id: 1415580:GDAP1
uniprot id: A0A6P7X760
names: Similarity
messages: Belongs to the GST superfamily.

1415580:RBM48
gene id: 1415580:RBM48
uniprot id: A0A6P7XZT2
names: Similarity
messages: Belongs to the RBM48 family.

1415580:EP300
gene id: 1415580:EP300
uniprot id: A0A6P7Y224
names: Subcellular Location Annotation
messages: Cytoplasm

1415580:IMMP1L
gene id: 1415580:IMMP1L
uniprot id: A0A6P7XVK6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26 family.
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
messages: Mitochondrion inner membrane

1415580:GNAS
gene id: 1415580:GNAS
uniprot id: A0A6P7YPM2
uniprot id: A0A6P7YUJ5
uniprot id: A0A6P7YUN7
names: Similarity
messages: Belongs to the G-alpha family. G(s) subfamily.

1415580:HS3ST1
gene id: 1415580:HS3ST1
uniprot id: A0A6P7XE40
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

1415580:SLC25A12
gene id: 1415580:SLC25A12
uniprot id: A0A6P7YLF6
uniprot id: A0A6P7YQW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1415580:SYT2
gene id: 1415580:SYT2
uniprot id: A0A6P7ZGC1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: Membrane
messages: chromaffin granule membrane
messages: synaptic vesicle membrane

1415580:LOC115482143
gene id: 1415580:LOC115482143
uniprot id: A0A6P7ZUH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115465017
gene id: 1415580:LOC115465017
uniprot id: A0A6P7XLR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 11 family.
messages: Golgi stack membrane
messages: Membrane

1415580:RPF1
gene id: 1415580:RPF1
uniprot id: A0A6P7YEY4
names: Subcellular Location Annotation
messages: nucleolus

1415580:PPP6R1
gene id: 1415580:PPP6R1
uniprot id: A0A6P7XSR9
names: Similarity
messages: Belongs to the SAPS family.

1415580:SOX2
gene id: 1415580:SOX2
uniprot id: A0A6P7ZC32
names: Subcellular Location Annotation
messages: Nucleus

1415580:UCK2
gene id: 1415580:UCK2
uniprot id: A0A6P7YBU5
uniprot id: A0A6P7YH77
uniprot id: A0A6P7YHL4
names: Similarity
names: Subunit
messages: Belongs to the uridine kinase family.
messages: Homotetramer.

1415580:CEP290
gene id: 1415580:CEP290
uniprot id: A0A6P7YS00
names: Subcellular Location Annotation
messages: cilium basal body

1415580:SLC9A1
gene id: 1415580:SLC9A1
uniprot id: A0A6P7ZBY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Membrane

1415580:CSNK1G1
gene id: 1415580:CSNK1G1
uniprot id: A0A6P7WKR9
uniprot id: A0A6P7X068
uniprot id: A0A6P7X198
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

1415580:UPK1B
gene id: 1415580:UPK1B
uniprot id: A0A6P7Y7J8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Heterodimer with uroplakin-3A (UPK3A) or uroplakin-3B (UPK3B).
messages: Membrane

1415580:SYNGR4
gene id: 1415580:SYNGR4
uniprot id: A0A6P7XDR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

1415580:CCNH
gene id: 1415580:CCNH
uniprot id: A0A6P7XG54
names: Function
names: Similarity
names: Subunit
messages: Associates primarily with CDK7 and MAT1 to form the CAK complex. CAK can further associate with the core-TFIIH to form the TFIIH basal transcription factor.
messages: Belongs to the cyclin family.
messages: Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

1415580:RXRB
gene id: 1415580:RXRB
uniprot id: A0A6P7XBY9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

1415580:PRR5L
gene id: 1415580:PRR5L
uniprot id: A0A6P7XQE2
names: Similarity
messages: Belongs to the PROTOR family.

1415580:GALNT1
gene id: 1415580:GALNT1
uniprot id: A0A6P7XYN7
uniprot id: A0A6P7XYP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

1415580:LOC115472439
gene id: 1415580:LOC115472439
uniprot id: A0A6P7YC14
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

1415580:LOC115481339
gene id: 1415580:LOC115481339
uniprot id: A0A6P7ZAB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1415580:TRIP10
gene id: 1415580:TRIP10
uniprot id: A0A6P7XJR4
uniprot id: A0A6P7XQP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNBP1 family.
messages: Cell membrane
messages: Lysosome
messages: Membrane
messages: cell cortex

1415580:MFAP3
gene id: 1415580:MFAP3
uniprot id: A0A6P7YNZ9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:EDEM3
gene id: 1415580:EDEM3
uniprot id: A0A6P7Y1S2
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

1415580:PMVK
gene id: 1415580:PMVK
uniprot id: A0A6P7X0H4
uniprot id: A0A6P7X1N1
names: Subcellular Location Annotation
messages: cytosol

1415580:PARD3B
gene id: 1415580:PARD3B
uniprot id: A0A6P7YL79
uniprot id: A0A6P7YRG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR3 family.
messages: Cell junction
messages: Endomembrane system

1415580:CEBPD
gene id: 1415580:CEBPD
uniprot id: A0A6P7Z3F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. C/EBP subfamily.
messages: Nucleus

1415580:CDIP1
gene id: 1415580:CDIP1
uniprot id: A0A6P7YYL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane
messages: Membrane

1415580:MPL
gene id: 1415580:MPL
uniprot id: A0A6P7YEA1
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.

1415580:PPDPF
gene id: 1415580:PPDPF
uniprot id: A0A6P7YXW4
names: Similarity
messages: Belongs to the PPDPF family.

1415580:POMT1
gene id: 1415580:POMT1
uniprot id: A0A6P7YFF1
uniprot id: A0A6P7YKN4
uniprot id: A0A6P7YKW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

1415580:ANP32E
gene id: 1415580:ANP32E
uniprot id: A0A6P7WI87
names: Similarity
messages: Belongs to the ANP32 family.

1415580:MC5R
gene id: 1415580:MC5R
uniprot id: A0A6P7X5X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.

1415580:TSSK6
gene id: 1415580:TSSK6
uniprot id: A0A6P7ZFR5
names: Similarity
messages: Belongs to the protein kinase superfamily.

1415580:TCP11L1
gene id: 1415580:TCP11L1
uniprot id: A0A6P7Y104
names: Similarity
messages: Belongs to the TCP11 family.

1415580:MED19
gene id: 1415580:MED19
uniprot id: A0A6P7WFP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 19 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1415580:LOC115463509
gene id: 1415580:LOC115463509
uniprot id: A0A6P7XH03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-delta family.
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

1415580:OPN1LW
gene id: 1415580:OPN1LW
uniprot id: A0A6P7XCN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

1415580:LOC115457119
gene id: 1415580:LOC115457119
uniprot id: A0A6P7WGN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115466757
gene id: 1415580:LOC115466757
uniprot id: A0A6P7XEW9
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion membrane

1415580:LOC115475021
gene id: 1415580:LOC115475021
uniprot id: A0A6P7YTL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

1415580:RPL23
gene id: 1415580:RPL23
uniprot id: A0A6P7ZS70
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

1415580:LOC115469968
gene id: 1415580:LOC115469968
uniprot id: A0A6P7XT80
names: Similarity
messages: Belongs to the peptidase M24B family.

1415580:LOC115464476
gene id: 1415580:LOC115464476
uniprot id: A0A6P7X532
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:MAP2
gene id: 1415580:MAP2
uniprot id: A0A6P7YTV1
names: Subcellular Location Annotation
messages: cytoskeleton

1415580:CREBBP
gene id: 1415580:CREBBP
uniprot id: A0A6P7YVY5
names: Subcellular Location Annotation
messages: Cytoplasm

1415580:EGR1
gene id: 1415580:EGR1
uniprot id: A0A6P7YT76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus
messages: Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death.

1415580:FLT3
gene id: 1415580:FLT3
uniprot id: A0A6P7XLB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

1415580:LOC115474174
gene id: 1415580:LOC115474174
uniprot id: A0A6P7YKP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

1415580:LOC115462124
gene id: 1415580:LOC115462124
uniprot id: A0A6P7WXQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115460541
gene id: 1415580:LOC115460541
uniprot id: A0A6P7WYD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:IGF1R
gene id: 1415580:IGF1R
uniprot id: A0A6P7X4U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

1415580:CKAP5
gene id: 1415580:CKAP5
uniprot id: A0A6P7XUS3
uniprot id: A0A6P7Y121
uniprot id: A0A6P7Y1M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOG/XMAP215 family.
messages: kinetochore

1415580:LOC115469892
gene id: 1415580:LOC115469892
uniprot id: A0A6P7Y106
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shootin family.
messages: axon
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

1415580:DRD5
gene id: 1415580:DRD5
uniprot id: A0A6P7X3T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:UPF3A
gene id: 1415580:UPF3A
uniprot id: A0A6P7XY92
names: Similarity
messages: Belongs to the RENT3 family.

1415580:EDA
gene id: 1415580:EDA
uniprot id: A0A6P7YNC7
names: Similarity
messages: Belongs to the tumor necrosis factor family.

1415580:UBR2
gene id: 1415580:UBR2
uniprot id: A0A6P7XEK4
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

1415580:UNC45A
gene id: 1415580:UNC45A
uniprot id: A0A6P7WQN4
uniprot id: A0A6P7WWJ6
uniprot id: A0A6P7X4L7
names: Subcellular Location Annotation
messages: perinuclear region

1415580:FZD8
gene id: 1415580:FZD8
uniprot id: A0A6P7XVV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Membrane

1415580:NPTX2
gene id: 1415580:NPTX2
uniprot id: A0A6P7YWX0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:SUSD5
gene id: 1415580:SUSD5
uniprot id: A0A6P7Y8U6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:CACNG7
gene id: 1415580:CACNG7
uniprot id: A0A6P7XDQ8
uniprot id: A0A6P7XSM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2.

1415580:LOC115457344
gene id: 1415580:LOC115457344
uniprot id: A0A6P7WNI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115475702
gene id: 1415580:LOC115475702
uniprot id: A0A6P7YW26
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

1415580:LOC115476808
gene id: 1415580:LOC115476808
uniprot id: A0A6P7YW95
names: Similarity
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.

1415580:TRIM72
gene id: 1415580:TRIM72
uniprot id: A0A6P7YMG0
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle membrane
messages: sarcolemma

1415580:LIAS
gene id: 1415580:LIAS
uniprot id: A0A6P7WVF8
uniprot id: A0A6P7X3Z6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Mitochondrion

1415580:LOC115457875
gene id: 1415580:LOC115457875
uniprot id: A0A6P7WJB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:HSD3B7
gene id: 1415580:HSD3B7
uniprot id: A0A6P7YFM7
uniprot id: A0A6P7YNA5
uniprot id: A0A6P7YSN0
names: Similarity
messages: Belongs to the 3-beta-HSD family.

1415580:TUBGCP5
gene id: 1415580:TUBGCP5
uniprot id: A0A6P7Y2A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

1415580:MBOAT7
gene id: 1415580:MBOAT7
uniprot id: A0A6P7XMK3
uniprot id: A0A6P7XTH6
names: Subcellular Location Annotation
messages: Membrane

1415580:IL7R
gene id: 1415580:IL7R
uniprot id: A0A6P7X5M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Membrane
messages: Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP).
messages: The IL7 receptor is a heterodimer of IL7R and IL2RG. The TSLP receptor is a heterodimer of CRLF2 and IL7R.

1415580:PRKAA2
gene id: 1415580:PRKAA2
uniprot id: A0A6P7YHB4
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

1415580:LOC115470131
gene id: 1415580:LOC115470131
uniprot id: A0A6P7Y735
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LOC115466076
gene id: 1415580:LOC115466076
uniprot id: A0A6P7XBK0
uniprot id: A0A6P7XIB3
names: Subcellular Location Annotation
messages: nucleolus

1415580:LOC115480824
gene id: 1415580:LOC115480824
uniprot id: A0A6P7ZD02
uniprot id: A0A6P7ZNK2
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

1415580:TMEM86A
gene id: 1415580:TMEM86A
uniprot id: A0A6P7Y1Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

1415580:DPEP1
gene id: 1415580:DPEP1
uniprot id: A0A6P7YCB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
messages: Cell membrane
messages: Homodimer; disulfide-linked.
messages: Independently of its dipeptidase activity, acts as an adhesion receptor for neutrophil recruitment from bloodstream into inflamed lungs and liver.
messages: Membrane

1415580:OPA1
gene id: 1415580:OPA1
uniprot id: A0A6P7Z8T9
uniprot id: A0A6P7ZCB9
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane

1415580:ZFPM1
gene id: 1415580:ZFPM1
uniprot id: A0A6P7Y625
names: Subcellular Location Annotation
messages: Nucleus

1415580:PRDM4
gene id: 1415580:PRDM4
uniprot id: A0A6P7YS35
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115457154
gene id: 1415580:LOC115457154
uniprot id: A0A6P7WPY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:TWISTNB
gene id: 1415580:TWISTNB
uniprot id: A0A6P7Y3S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA43 RNA polymerase subunit family.
messages: nucleolus

1415580:FAM110C
gene id: 1415580:FAM110C
uniprot id: A0A6P7XH20
names: Similarity
messages: Belongs to the FAM110 family.

1415580:SGMS1
gene id: 1415580:SGMS1
uniprot id: A0A6P7XU13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

1415580:LOC115463406
gene id: 1415580:LOC115463406
uniprot id: A0A6P7XGE4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the annexin family.
messages: Cell membrane
messages: Cytoplasm
messages: Lateral cell membrane
messages: Membrane
messages: Nucleus
messages: The full-length protein can bind eight Ca(2+) ions via the annexin repeats. Calcium binding causes a major conformation change that modifies dimer contacts and leads to surface exposure of the N-terminal phosphorylation sites; in the absence of Ca(2+), these sites are buried in the interior of the protein core. The N-terminal region becomes disordered in response to calcium-binding.
messages: cilium

1415580:LOC115480692
gene id: 1415580:LOC115480692
uniprot id: A0A6P7Z7R3
uniprot id: A0A6P7ZGA5
uniprot id: A0A6P7ZKG7
uniprot id: A0A6P7ZMK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

1415580:LOC115457363
gene id: 1415580:LOC115457363
uniprot id: A0A6P7WWL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:CDK5RAP1
gene id: 1415580:CDK5RAP1
uniprot id: A0A6P7YUV5
names: Similarity
messages: Belongs to the methylthiotransferase family. MiaB subfamily.

1415580:LOC115459872
gene id: 1415580:LOC115459872
uniprot id: A0A6P7X4P9
uniprot id: A0A6P7X5X8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1415580:TM4SF5
gene id: 1415580:TM4SF5
uniprot id: A0A6P7X084
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

1415580:TCTEX1D2
gene id: 1415580:TCTEX1D2
uniprot id: A0A6P7Z5Q7
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

1415580:SLC52A2
gene id: 1415580:SLC52A2
uniprot id: A0A6P7WSE8
uniprot id: A0A6P7X6A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

1415580:MAN2C1
gene id: 1415580:MAN2C1
uniprot id: A0A6P7WNK7
uniprot id: A0A6P7WQI4
uniprot id: A0A6P7WQK1
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1415580:LOC115466544
gene id: 1415580:LOC115466544
uniprot id: A0A6P7XSQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 11 family.
messages: Golgi stack membrane
messages: Membrane

1415580:KIF20A
gene id: 1415580:KIF20A
uniprot id: A0A6P7YWJ3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

1415580:ERBB3
gene id: 1415580:ERBB3
uniprot id: A0A6P7XHD0
uniprot id: A0A6P7XPJ5
uniprot id: A0A6P7XQC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

1415580:FOXF2
gene id: 1415580:FOXF2
uniprot id: A0A6P7X5U1
names: Subcellular Location Annotation
messages: Nucleus

1415580:SLC25A36
gene id: 1415580:SLC25A36
uniprot id: A0A6P7Z6M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1415580:ANO3
gene id: 1415580:ANO3
uniprot id: A0A6P7XMH4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:LOC115480337
gene id: 1415580:LOC115480337
uniprot id: A0A6P7Z646
uniprot id: A0A6P7ZHY0
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

1415580:LOC115457381
gene id: 1415580:LOC115457381
uniprot id: A0A6P7WWN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115480310
gene id: 1415580:LOC115480310
uniprot id: A0A6P7Z5Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

1415580:GDF2
gene id: 1415580:GDF2
uniprot id: A0A6P7XZC2
names: Similarity
messages: Belongs to the TGF-beta family.

1415580:LOC115457794
gene id: 1415580:LOC115457794
uniprot id: A0A6P7WIX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Cell membrane
messages: Membrane

1415580:NIPAL1
gene id: 1415580:NIPAL1
uniprot id: A0A6P7WVK0
uniprot id: A0A6P7X441
uniprot id: A0A6P7X9G1
uniprot id: A0A6P7XAR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

1415580:LSM5
gene id: 1415580:LSM5
uniprot id: A0A6P7XXT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.

1415580:EIF1AX
gene id: 1415580:EIF1AX
uniprot id: A0A6P7XZY5
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

1415580:LOC115463558
gene id: 1415580:LOC115463558
uniprot id: A0A6P7X9S5
names: Similarity
messages: Belongs to the perilipin family.

1415580:PTBP1
gene id: 1415580:PTBP1
uniprot id: A0A6P7Z970
names: Subcellular Location Annotation
messages: Nucleus

1415580:RPS6KA4
gene id: 1415580:RPS6KA4
uniprot id: A0A6P7ZAQ8
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

1415580:ANKRD13D
gene id: 1415580:ANKRD13D
uniprot id: A0A6P7WEQ4
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

1415580:LOC115476004
gene id: 1415580:LOC115476004
uniprot id: A0A6P7YX19
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:MDH2
gene id: 1415580:MDH2
uniprot id: A0A6P7WF23
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

1415580:LOC115464777
gene id: 1415580:LOC115464777
uniprot id: A0A6P7XCN6
names: Similarity
messages: Belongs to the RCAN family.

1415580:RPL31
gene id: 1415580:RPL31
uniprot id: A0A6P7Y2R3
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Component of the large ribosomal subunit.

1415580:PEX13
gene id: 1415580:PEX13
uniprot id: A0A6P7X8X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-13 family.
messages: Membrane
messages: Peroxisome membrane

1415580:ADORA1
gene id: 1415580:ADORA1
uniprot id: A0A6P7ZPR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

1415580:LARS1
gene id: 1415580:LARS1
uniprot id: A0A6P7YJK7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1415580:IRF9
gene id: 1415580:IRF9
uniprot id: A0A6P7WQ45
uniprot id: A0A6P7WY69
uniprot id: A0A6P7WZ87
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

1415580:LOC115457465
gene id: 1415580:LOC115457465
uniprot id: A0A6P7WWW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the APH-1 family.
messages: Component of the gamma-secretase complex.
messages: Membrane
messages: Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors.

1415580:LOC115466742
gene id: 1415580:LOC115466742
uniprot id: A0A6P7XLK0
names: Similarity
messages: Belongs to the intermediate filament family.

1415580:LOC115474404
gene id: 1415580:LOC115474404
uniprot id: A0A6P7YLP4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1415580:LOC115474373
gene id: 1415580:LOC115474373
uniprot id: A0A6P7YR22
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homotetramer.
messages: Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.
messages: cytosol

1415580:LOC115481220
gene id: 1415580:LOC115481220
uniprot id: A0A6P7X5J9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1415580:SLC7A6OS
gene id: 1415580:SLC7A6OS
uniprot id: A0A6P7Y554
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IWR1/SLC7A6OS family.
messages: Cytoplasm
messages: Directs RNA polymerase II nuclear import.
messages: Nucleus

1415580:TIGD5
gene id: 1415580:TIGD5
uniprot id: A0A6P7ZP93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tigger transposable element derived protein family.
messages: Nucleus

1415580:MED15
gene id: 1415580:MED15
uniprot id: A0A6P7Z6B5
uniprot id: A0A6P7ZB80
uniprot id: A0A6P7ZEJ8
uniprot id: A0A6P7ZHI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 15 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1415580:MLLT11
gene id: 1415580:MLLT11
uniprot id: A0A6P7WSW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLLT11 family.
messages: Nucleus
messages: centrosome

1415580:PRKG2
gene id: 1415580:PRKG2
uniprot id: A0A6P7Y701
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

1415580:LOC115466211
gene id: 1415580:LOC115466211
uniprot id: A0A6P7XRW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM NELF-E family.
messages: Chromosome
messages: Nucleus

1415580:LOC115479696
gene id: 1415580:LOC115479696
uniprot id: A0A6P7X5J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1415580:YJU2
gene id: 1415580:YJU2
uniprot id: A0A6P7ZFW4
uniprot id: A0A6P7ZGD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CWC16 family. YJU2 subfamily.
messages: Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.
messages: Nucleus
messages: Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex.

1415580:LOC115469455
gene id: 1415580:LOC115469455
uniprot id: A0A6P7XZH2
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

1415580:EZH2
gene id: 1415580:EZH2
uniprot id: A0A6P7XVN9
uniprot id: A0A6P7XVS3
uniprot id: A0A6P7Y2V2
uniprot id: A0A6P7Y304
uniprot id: A0A6P7Y3Q6
uniprot id: A0A6P7Y3S6
uniprot id: A0A6P7Y8T7
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115461963
gene id: 1415580:LOC115461963
uniprot id: A0A6P7XCI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115472885
gene id: 1415580:LOC115472885
uniprot id: A0A6P7YDW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: clathrin-coated vesicle membrane

1415580:PANX1
gene id: 1415580:PANX1
uniprot id: A0A6P7XPY9
uniprot id: A0A6P7XWZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

1415580:KPNA7
gene id: 1415580:KPNA7
uniprot id: A0A6P7YUC3
names: Similarity
messages: Belongs to the importin alpha family.

1415580:LOC115457355
gene id: 1415580:LOC115457355
uniprot id: A0A6P7WH89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115477565
gene id: 1415580:LOC115477565
uniprot id: A0A6P7Z4G5
names: Similarity
messages: Belongs to the CRISP family.

1415580:SESN3
gene id: 1415580:SESN3
uniprot id: A0A6P7XKZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

1415580:QRFP
gene id: 1415580:QRFP
uniprot id: A0A6P7YCD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFamide neuropeptide family.
messages: Secreted

1415580:MSRB1
gene id: 1415580:MSRB1
uniprot id: A0A6P7YLW8
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.

1415580:CFAP43
gene id: 1415580:CFAP43
uniprot id: A0A6P7Y1D3
names: Similarity
messages: Belongs to the CFAP43 family.

1415580:KCNK4
gene id: 1415580:KCNK4
uniprot id: A0A6P7ZPI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

1415580:LOC115464912
gene id: 1415580:LOC115464912
uniprot id: A0A6P7XKH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

1415580:ZNF711
gene id: 1415580:ZNF711
uniprot id: A0A6P7YU48
names: Subcellular Location Annotation
messages: Nucleus

1415580:SCNM1
gene id: 1415580:SCNM1
uniprot id: A0A6P7WL81
uniprot id: A0A6P7WS99
names: Function
names: Subcellular Location Annotation
messages: Nucleus speckle
messages: Plays a role in alternative splicing of pre-mRNAs, possibly by contributing to the selection of non-consensus donor sites.
messages: nucleoplasm

1415580:DNASE2B
gene id: 1415580:DNASE2B
uniprot id: A0A6P7YFL0
names: Similarity
messages: Belongs to the DNase II family.

1415580:SLC25A6
gene id: 1415580:SLC25A6
uniprot id: A0A6P7Y4F2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

1415580:BARX1
gene id: 1415580:BARX1
uniprot id: A0A6P7YI85
names: Subcellular Location Annotation
messages: Nucleus

1415580:MYC
gene id: 1415580:MYC
uniprot id: A0A6P7Z6K0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus
messages: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.

1415580:CRELD2
gene id: 1415580:CRELD2
uniprot id: A0A6P7YZB1
names: Caution
names: Similarity
messages: Belongs to the CRELD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115461964
gene id: 1415580:LOC115461964
uniprot id: A0A6P7XBD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:TMEM88
gene id: 1415580:TMEM88
uniprot id: A0A6P7WQB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM88 family.
messages: Membrane

1415580:TNKS
gene id: 1415580:TNKS
uniprot id: A0A6P7XCV9
names: Similarity
messages: Belongs to the ARTD/PARP family.

1415580:NBN
gene id: 1415580:NBN
uniprot id: A0A6P7Z947
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.
messages: Component of the MRN complex.
messages: Nucleus
messages: telomere

1415580:TFDP1
gene id: 1415580:TFDP1
uniprot id: A0A6P7XPT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

1415580:MMACHC
gene id: 1415580:MMACHC
uniprot id: A0A6P7Y9X9
names: Similarity
messages: Belongs to the MMACHC family.

1415580:RLN3
gene id: 1415580:RLN3
uniprot id: A0A6P7XKF9
names: Similarity
messages: Belongs to the insulin family.

1415580:LOC115463556
gene id: 1415580:LOC115463556
uniprot id: A0A6P7X9R5
uniprot id: A0A6P7XC02
uniprot id: A0A6P7XIE0
names: Similarity
messages: Belongs to the perilipin family.

1415580:LOC115462404
gene id: 1415580:LOC115462404
uniprot id: A0A6P7X772
names: Similarity
messages: Belongs to the DNase I family.

1415580:DOLPP1
gene id: 1415580:DOLPP1
uniprot id: A0A6P7YFM1
uniprot id: A0A6P7YKU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dolichyldiphosphatase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate.

1415580:BABAM2
gene id: 1415580:BABAM2
uniprot id: A0A6P7X851
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BABAM2 family.
messages: Component of the ARISC complex. Component of the BRCA1-A complex. Component of the BRISC complex. Binds polyubiquitin.
messages: Contains 2 ubiquitin-conjugating enzyme family-like (UEV-like) regions. These regions lack the critical Cys residues required for ubiquitination but retain the ability to bind ubiquitin.
messages: Cytoplasm
messages: May play a role in homeostasis or cellular differentiation in cells of neural, epithelial and germline origins. May also act as a death receptor-associated anti-apoptotic protein, which inhibits the mitochondrial apoptotic pathway.
messages: Nucleus

1415580:LOC115457738
gene id: 1415580:LOC115457738
uniprot id: A0A6P7WY13
uniprot id: A0A6P7WZ14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:SKA2
gene id: 1415580:SKA2
uniprot id: A0A6P8A152
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKA2 family.
messages: spindle

1415580:LOC115460477
gene id: 1415580:LOC115460477
uniprot id: A0A6P7WY71
names: Similarity
messages: Belongs to the UPF0598 family.

1415580:LAMP5
gene id: 1415580:LAMP5
uniprot id: A0A6P7XB48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane

1415580:ANP32A
gene id: 1415580:ANP32A
uniprot id: A0A6P7WR52
names: Similarity
messages: Belongs to the ANP32 family.

1415580:TADA3
gene id: 1415580:TADA3
uniprot id: A0A6P7Y8I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGG1 family.
messages: Nucleus

1415580:TCP11L2
gene id: 1415580:TCP11L2
uniprot id: A0A6P7Z106
uniprot id: A0A6P7Z110
names: Similarity
messages: Belongs to the TCP11 family.

1415580:XRCC5
gene id: 1415580:XRCC5
uniprot id: A0A6P7YLW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku80 family.
messages: Nucleus

1415580:MBP
gene id: 1415580:MBP
uniprot id: A0A6P7YWM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin basic protein family.
messages: Myelin membrane

1415580:LOC115479886
gene id: 1415580:LOC115479886
uniprot id: A0A6P7Z930
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115464651
gene id: 1415580:LOC115464651
uniprot id: A0A6P7XCA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:MRPL20
gene id: 1415580:MRPL20
uniprot id: A0A6P7WUZ5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.

1415580:LOC115478066
gene id: 1415580:LOC115478066
uniprot id: A0A6P7YVF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

1415580:ARVCF
gene id: 1415580:ARVCF
uniprot id: A0A6P7Z8N1
uniprot id: A0A6P7ZBF3
uniprot id: A0A6P7ZEQ5
names: Similarity
messages: Belongs to the beta-catenin family.

1415580:MGA
gene id: 1415580:MGA
uniprot id: A0A6P7Z6M3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

1415580:FBLN7
gene id: 1415580:FBLN7
uniprot id: A0A6P7XZJ1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:CAMLG
gene id: 1415580:CAMLG
uniprot id: A0A6P7YYA9
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET1/WRB, acts as a membrane receptor for soluble GET3/TRC40, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. Required for the stability of GET1. Stimulates calcium signaling in T cells through its involvement in elevation of intracellular calcium. Essential for the survival of peripheral follicular B cells.

1415580:LOC115470224
gene id: 1415580:LOC115470224
uniprot id: A0A6P7Y1U8
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

1415580:SELENBP1
gene id: 1415580:SELENBP1
uniprot id: A0A6P7WJD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenium-binding protein family.
messages: Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria. Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport.
messages: Membrane
messages: Nucleus
messages: cytosol

1415580:INO80C
gene id: 1415580:INO80C
uniprot id: A0A6P7X6T4
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115466130
gene id: 1415580:LOC115466130
uniprot id: A0A6P7XKL6
names: Similarity
messages: Belongs to the AKAP95 family.

1415580:LOC115481213
gene id: 1415580:LOC115481213
uniprot id: A0A6P7WV85
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1415580:FGF16
gene id: 1415580:FGF16
uniprot id: A0A6P7YL29
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

1415580:EMC2
gene id: 1415580:EMC2
uniprot id: A0A6P7ZEU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC2 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.

1415580:LOC115468460
gene id: 1415580:LOC115468460
uniprot id: A0A6P7XZV2
names: Similarity
messages: Belongs to the cytochrome P450 family.

1415580:MAN2B2
gene id: 1415580:MAN2B2
uniprot id: A0A6P7WV36
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

1415580:ZFYVE28
gene id: 1415580:ZFYVE28
uniprot id: A0A6P7WUY6
uniprot id: A0A6P7X8U0
names: Similarity
messages: Belongs to the lst-2 family.

1415580:IFT43
gene id: 1415580:IFT43
uniprot id: A0A6P7YUM2
uniprot id: A0A6P7Z0X2
uniprot id: A0A6P7Z2B9
names: Similarity
messages: Belongs to the IFT43 family.

1415580:LOC115480897
gene id: 1415580:LOC115480897
uniprot id: A0A6P7ZHT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1415580:LOC115469500
gene id: 1415580:LOC115469500
uniprot id: A0A6P7XZU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RING-box family.
messages: Cytoplasm

1415580:LOC115457155
gene id: 1415580:LOC115457155
uniprot id: A0A6P7WWY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115464430
gene id: 1415580:LOC115464430
uniprot id: A0A6P7XBJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

1415580:LOC115461731
gene id: 1415580:LOC115461731
uniprot id: A0A6P7XBV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sprouty family.
messages: Cytoplasm
messages: Membrane

1415580:LOC115480737
gene id: 1415580:LOC115480737
uniprot id: A0A6P7ZCM8
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:TMEM242
gene id: 1415580:TMEM242
uniprot id: A0A6P7XFV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM242 family.
messages: Membrane

1415580:CPEB4
gene id: 1415580:CPEB4
uniprot id: A0A6P7YZ26
names: Similarity
messages: Belongs to the RRM CPEB family.

1415580:AGAP1
gene id: 1415580:AGAP1
uniprot id: A0A6P7YG55
uniprot id: A0A6P7YNT5
names: Similarity
messages: Belongs to the centaurin gamma-like family.

1415580:TUT7
gene id: 1415580:TUT7
uniprot id: A0A6P7X8B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B-like family.
messages: Cytoplasm

1415580:CZIB
gene id: 1415580:CZIB
uniprot id: A0A6P7YGG5
names: Similarity
messages: Belongs to the UPF0587 family.

1415580:PPT1
gene id: 1415580:PPT1
uniprot id: A0A6P7ZB95
uniprot id: A0A6P7ZEL0
names: Similarity
messages: Belongs to the palmitoyl-protein thioesterase family.

1415580:LOC115469681
gene id: 1415580:LOC115469681
uniprot id: A0A6P7Y6F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

1415580:LNPK
gene id: 1415580:LNPK
uniprot id: A0A6P7YEW0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Homodimer; homodimerization requires the C4-type zinc finger motif and decreases during mitosis in a phosphorylation-dependent manner.
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

1415580:CXCL13
gene id: 1415580:CXCL13
uniprot id: A0A6P7WZ46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

1415580:LOC115473900
gene id: 1415580:LOC115473900
uniprot id: A0A6P7YBS7
names: Similarity
messages: Belongs to the TMEM14 family.

1415580:LOC115466602
gene id: 1415580:LOC115466602
uniprot id: A0A6P7XMP2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

1415580:LOC115460545
gene id: 1415580:LOC115460545
uniprot id: A0A6P7X6F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:GMPR
gene id: 1415580:GMPR
uniprot id: A0A6P7X0C0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

1415580:PSMD11
gene id: 1415580:PSMD11
uniprot id: A0A6P7ZCX8
uniprot id: A0A6P7ZUT2
names: Similarity
messages: Belongs to the proteasome subunit S9 family.

1415580:EIF4H
gene id: 1415580:EIF4H
uniprot id: A0A6P7ZF63
names: Function
names: Subcellular Location Annotation
messages: Stimulates the RNA helicase activity of EIF4A in the translation initiation complex. Binds weakly mRNA.
messages: perinuclear region

1415580:CCDC181
gene id: 1415580:CCDC181
uniprot id: A0A6P7Y480
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC181 family.
messages: Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids.
messages: cytoskeleton
messages: flagellum

1415580:CDC5L
gene id: 1415580:CDC5L
uniprot id: A0A6P7XVC1
names: Similarity
messages: Belongs to the CEF1 family.

1415580:SEMA4B
gene id: 1415580:SEMA4B
uniprot id: A0A6P7WWL0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115466437
gene id: 1415580:LOC115466437
uniprot id: A0A6P7XSU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THAP1 family.
messages: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes.
messages: nucleoplasm

1415580:TNFSF14
gene id: 1415580:TNFSF14
uniprot id: A0A6P7XQQ1
names: Similarity
messages: Belongs to the tumor necrosis factor family.

1415580:GPX8
gene id: 1415580:GPX8
uniprot id: A0A6P7WY08
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1415580:LOC115471031
gene id: 1415580:LOC115471031
uniprot id: A0A6P7YBY1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:METTL15
gene id: 1415580:METTL15
uniprot id: A0A6P7XMG4
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmH family.

1415580:LMBR1
gene id: 1415580:LMBR1
uniprot id: A0A6P7XFZ7
uniprot id: A0A6P7XUX3
names: Similarity
messages: Belongs to the LIMR family.

1415580:FDPS
gene id: 1415580:FDPS
uniprot id: A0A6P7X0L2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1415580:LOC115462454
gene id: 1415580:LOC115462454
uniprot id: A0A6P7XCJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 32 family.
messages: Golgi apparatus membrane

1415580:SLC25A47
gene id: 1415580:SLC25A47
uniprot id: A0A6P7Z5F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1415580:YIPF3
gene id: 1415580:YIPF3
uniprot id: A0A6P7XMV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in the maintenance of the Golgi structure. May play a role in hematopoiesis.
messages: Membrane
messages: cis-Golgi network membrane

1415580:ESD
gene id: 1415580:ESD
uniprot id: A0A6P7XV28
uniprot id: A0A6P7Y043
uniprot id: A0A6P7Y0N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the esterase D family.
messages: Cytoplasmic vesicle
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1415580:NME5
gene id: 1415580:NME5
uniprot id: A0A6P7YQ88
names: Similarity
messages: Belongs to the NDK family.

1415580:CAPN15
gene id: 1415580:CAPN15
uniprot id: A0A6P7YQS5
uniprot id: A0A6P7YVJ6
uniprot id: A0A6P7YVM6
names: Similarity
messages: Belongs to the peptidase C2 family.

1415580:SLC17A9
gene id: 1415580:SLC17A9
uniprot id: A0A6P7YWZ0
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115480372
gene id: 1415580:LOC115480372
uniprot id: A0A6P7ZHG1
names: Similarity
messages: Belongs to the gonadal family.

1415580:LOC115473504
gene id: 1415580:LOC115473504
uniprot id: A0A6P7YHF7
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Interacts with NCDN.
messages: Membrane

1415580:TAF7L
gene id: 1415580:TAF7L
uniprot id: A0A6P7YFC8
uniprot id: A0A6P7YN09
uniprot id: A0A6P7YSB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

1415580:E2F6
gene id: 1415580:E2F6
uniprot id: A0A6P7XNL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

1415580:AP4S1
gene id: 1415580:AP4S1
uniprot id: A0A6P7Z1M0
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

1415580:KCNMA1
gene id: 1415580:KCNMA1
uniprot id: A0A6P7Y7J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa1.1/KCNMA1 sub-subfamily.
messages: Membrane

1415580:GREB1L
gene id: 1415580:GREB1L
uniprot id: A0A6P7YN60
uniprot id: A0A6P7YZP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GREB1 family.
messages: Membrane

1415580:OSBPL9
gene id: 1415580:OSBPL9
uniprot id: A0A6P7Y0S5
uniprot id: A0A6P7Y0T1
uniprot id: A0A6P7Y824
uniprot id: A0A6P7Y829
uniprot id: A0A6P7Y836
uniprot id: A0A6P7Y864
uniprot id: A0A6P7Y869
uniprot id: A0A6P7YDL1
uniprot id: A0A6P7YDL6
uniprot id: A0A6P7YE88
uniprot id: A0A6P7YE93
uniprot id: A0A6P7YE98
names: Similarity
messages: Belongs to the OSBP family.

1415580:PMM2
gene id: 1415580:PMM2
uniprot id: A0A6P7YKP8
uniprot id: A0A6P7YST1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

1415580:LOC115464661
gene id: 1415580:LOC115464661
uniprot id: A0A6P7XEF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:DYNC1LI1
gene id: 1415580:DYNC1LI1
uniprot id: A0A6P7Y339
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

1415580:GSK3B
gene id: 1415580:GSK3B
uniprot id: A0A6P7Y9U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.
messages: Cytoplasm
messages: Nucleus

1415580:PLAA
gene id: 1415580:PLAA
uniprot id: A0A6P7XH80
uniprot id: A0A6P7XIB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PLAP family.
messages: Cytoplasm

1415580:LOC115464514
gene id: 1415580:LOC115464514
uniprot id: A0A6P7XKB7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:MYCBP2
gene id: 1415580:MYCBP2
uniprot id: A0A6P7XM78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RING-Cys relay (RCR) family.
messages: axon

1415580:SNTB1
gene id: 1415580:SNTB1
uniprot id: A0A6P7Z581
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

1415580:NPR1
gene id: 1415580:NPR1
uniprot id: A0A6P7WZU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

1415580:LOC115466181
gene id: 1415580:LOC115466181
uniprot id: A0A6P7XKV1
uniprot id: A0A6P7XRR2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

1415580:LOC115457179
gene id: 1415580:LOC115457179
uniprot id: A0A6P7WQ13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115476715
gene id: 1415580:LOC115476715
uniprot id: A0A6P7YPA1
uniprot id: A0A6P7Z0U9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ6. Interacts with COQ9.
messages: Mitochondrion inner membrane

1415580:LOC115463190
gene id: 1415580:LOC115463190
uniprot id: A0A6P7X7Q8
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

1415580:LOC115475028
gene id: 1415580:LOC115475028
uniprot id: A0A6P7YGR4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:CHAC2
gene id: 1415580:CHAC2
uniprot id: A0A6P7X4D6
uniprot id: A0A6P7XD91
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

1415580:CKS2
gene id: 1415580:CKS2
uniprot id: A0A6P7X6X5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.

1415580:LOC115474520
gene id: 1415580:LOC115474520
uniprot id: A0A6P7YRS5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Cytoplasm
messages: Homodimer.

1415580:TSEN15
gene id: 1415580:TSEN15
uniprot id: A0A6P7YBR5
uniprot id: A0A6P7YH51
names: Similarity
messages: Belongs to the SEN15 family.

1415580:CFAP126
gene id: 1415580:CFAP126
uniprot id: A0A6P7WJR2
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the Flattop family.

1415580:POLR1A
gene id: 1415580:POLR1A
uniprot id: A0A6P7X390
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

1415580:NCBP1
gene id: 1415580:NCBP1
uniprot id: A0A6P7X3Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NCBP1 family.
messages: Nucleus

1415580:LOC115475139
gene id: 1415580:LOC115475139
uniprot id: A0A6P7YTY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLASP family.
messages: centrosome
messages: kinetochore
messages: trans-Golgi network

1415580:RPL34
gene id: 1415580:RPL34
uniprot id: A0A6P7X962
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

1415580:LOC115464714
gene id: 1415580:LOC115464714
uniprot id: A0A6P7XKT8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:COQ8B
gene id: 1415580:COQ8B
uniprot id: A0A6P7Z6Z6
uniprot id: A0A6P7ZFG2
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

1415580:CRCP
gene id: 1415580:CRCP
uniprot id: A0A6P7ZFW9
uniprot id: A0A6P7ZVU6
uniprot id: A0A6P7ZZG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC9 RNA polymerase subunit family.
messages: Nucleus

1415580:LOC115464407
gene id: 1415580:LOC115464407
uniprot id: A0A6P7XJ21
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LOC115474033
gene id: 1415580:LOC115474033
uniprot id: A0A6P7YJM3
uniprot id: A0A6P7YPX2
names: Similarity
messages: Belongs to the FAM122 family.

1415580:CERS3
gene id: 1415580:CERS3
uniprot id: A0A6P7WWT3
names: Subcellular Location Annotation
messages: Membrane

1415580:CRELD1
gene id: 1415580:CRELD1
uniprot id: A0A6P7YHW7
names: Caution
names: Similarity
messages: Belongs to the CRELD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:NR4A1
gene id: 1415580:NR4A1
uniprot id: A0A6P7XPV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

1415580:SPOPL
gene id: 1415580:SPOPL
uniprot id: A0A6P7YF78
uniprot id: A0A6P7YM42
uniprot id: A0A6P7YMU7
uniprot id: A0A6P7YS62
names: Similarity
messages: Belongs to the Tdpoz family.

1415580:PLLP
gene id: 1415580:PLLP
uniprot id: A0A6P7Y924
uniprot id: A0A6P7Y9T1
names: Subcellular Location Annotation
messages: Membrane

1415580:UBE3D
gene id: 1415580:UBE3D
uniprot id: A0A6P7XQY5
uniprot id: A0A6P7XWU6
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.

1415580:ELF3
gene id: 1415580:ELF3
uniprot id: A0A6P7ZT56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

1415580:LDLRAD2
gene id: 1415580:LDLRAD2
uniprot id: A0A6P7ZVF1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:TCHP
gene id: 1415580:TCHP
uniprot id: A0A6P7Z9G3
uniprot id: A0A6P7ZFL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCHP family.
messages: cytoskeleton

1415580:LOC115480526
gene id: 1415580:LOC115480526
uniprot id: A0A6P7ZKL4
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

1415580:PGM1
gene id: 1415580:PGM1
uniprot id: A0A6P7YII8
uniprot id: A0A6P7YIX9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1415580:LOC115465030
gene id: 1415580:LOC115465030
uniprot id: A0A6P7XLS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ11 subfamily.
messages: Membrane

1415580:SQLE
gene id: 1415580:SQLE
uniprot id: A0A6P7Z6D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the squalene monooxygenase family.
messages: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
messages: Endoplasmic reticulum membrane

1415580:LOC115470567
gene id: 1415580:LOC115470567
uniprot id: A0A6P7Y466
uniprot id: A0A6P7Y9C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

1415580:MALL
gene id: 1415580:MALL
uniprot id: A0A6P7XMZ9
names: Subcellular Location Annotation
messages: Membrane

1415580:ATPAF1
gene id: 1415580:ATPAF1
uniprot id: A0A6P7YFY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP11 family.
messages: Mitochondrion

1415580:ANKLE2
gene id: 1415580:ANKLE2
uniprot id: A0A6P7ZE51
names: Similarity
messages: Belongs to the ANKLE2 family.

1415580:HSBP1L1
gene id: 1415580:HSBP1L1
uniprot id: A0A6P7WXS5
names: Similarity
messages: Belongs to the HSBP1 family.

1415580:APOE
gene id: 1415580:APOE
uniprot id: A0A6P7YLV4
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

1415580:SLC46A1
gene id: 1415580:SLC46A1
uniprot id: A0A6P7XXU6
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115479671
gene id: 1415580:LOC115479671
uniprot id: A0A6P7ZAK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

1415580:GPR20
gene id: 1415580:GPR20
uniprot id: A0A6P7X0R1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:IMPAD1
gene id: 1415580:IMPAD1
uniprot id: A0A6P7YTK2
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1415580:LOC115461971
gene id: 1415580:LOC115461971
uniprot id: A0A6P7X3C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:TMEM245
gene id: 1415580:TMEM245
uniprot id: A0A6P7YBS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1415580:CD109
gene id: 1415580:CD109
uniprot id: A0A6P7XP44
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.

1415580:MPG
gene id: 1415580:MPG
uniprot id: A0A6P7Z018
names: Function
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.
messages: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.

1415580:SVOPL
gene id: 1415580:SVOPL
uniprot id: A0A6P7YUA8
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115474229
gene id: 1415580:LOC115474229
uniprot id: A0A6P7YKZ7
names: Similarity
messages: Belongs to the NRAMP family.

1415580:TMEM138
gene id: 1415580:TMEM138
uniprot id: A0A6P7XIR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM138 family.
messages: Membrane
messages: Required for ciliogenesis.
messages: Vacuole membrane
messages: cilium

1415580:MRPL32
gene id: 1415580:MRPL32
uniprot id: A0A6P7Y9C9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1415580:GNG7
gene id: 1415580:GNG7
uniprot id: A0A6P7Z845
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

1415580:CDCA7L
gene id: 1415580:CDCA7L
uniprot id: A0A6P7XXA9
uniprot id: A0A6P7XYF5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

1415580:LOC115458219
gene id: 1415580:LOC115458219
uniprot id: A0A6P7X079
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LOC115464420
gene id: 1415580:LOC115464420
uniprot id: A0A6P7X4X8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:CDKL1
gene id: 1415580:CDKL1
uniprot id: A0A6P7YVN4
names: Similarity
messages: Belongs to the protein kinase superfamily.

1415580:AGPS
gene id: 1415580:AGPS
uniprot id: A0A6P7YIX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
messages: Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids.
messages: Homodimer.
messages: Peroxisome

1415580:NLGN4X
gene id: 1415580:NLGN4X
uniprot id: A0A6P7XQT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

1415580:IGFBP1
gene id: 1415580:IGFBP1
uniprot id: A0A6P7Y2Z1
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds equally well IGF1 and IGF2.
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

1415580:LOC115457644
gene id: 1415580:LOC115457644
uniprot id: A0A6P7WIA1
uniprot id: A0A6P7WPL5
uniprot id: A0A6P7WPL9
uniprot id: A0A6P7WRL4
uniprot id: A0A6P7WXN0
uniprot id: A0A6P7WYM2
names: Similarity
messages: Belongs to the ARS2 family.

1415580:PKN1
gene id: 1415580:PKN1
uniprot id: A0A6P7XBN6
uniprot id: A0A6P7XKH2
uniprot id: A0A6P7XKH6
uniprot id: A0A6P7XQP9
uniprot id: A0A6P7XRC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Nucleus

1415580:GPM6B
gene id: 1415580:GPM6B
uniprot id: A0A6P7XQ12
uniprot id: A0A6P7XWU5
uniprot id: A0A6P7XXZ6
uniprot id: A0A6P7XY00
uniprot id: A0A6P7Y347
uniprot id: A0A6P7Y3L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

1415580:ACTR1B
gene id: 1415580:ACTR1B
uniprot id: A0A6P7Y432
names: Similarity
messages: Belongs to the actin family.

1415580:LOC115466539
gene id: 1415580:LOC115466539
uniprot id: A0A6P7XME2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 11 family.
messages: Golgi stack membrane
messages: Membrane

1415580:F13B
gene id: 1415580:F13B
uniprot id: A0A6P7YDX6
uniprot id: A0A6P7YJU9
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

1415580:PABPC1L
gene id: 1415580:PABPC1L
uniprot id: A0A6P7YNB3
uniprot id: A0A6P7YW41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

1415580:LOC115461550
gene id: 1415580:LOC115461550
uniprot id: A0A6P7WVT2
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

1415580:CD40LG
gene id: 1415580:CD40LG
uniprot id: A0A6P7YRH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a ligand for integrins, specifically ITGA5:ITGB1 and ITGAV:ITGB3; both integrins and the CD40 receptor are required for activation of CD40-CD40LG signaling, which have cell-type dependent effects, such as B-cell activation, NF-kappa-B signaling and anti-apoptotic signaling.
messages: Belongs to the tumor necrosis factor family.
messages: Cell surface
messages: Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
messages: Homotrimer.

1415580:SDF4
gene id: 1415580:SDF4
uniprot id: A0A6P7WMX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREC family.
messages: Golgi apparatus lumen

1415580:FZD6
gene id: 1415580:FZD6
uniprot id: A0A6P7ZCV0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Cell surface
messages: Cytoplasmic vesicle membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:LOC115457853
gene id: 1415580:LOC115457853
uniprot id: A0A6P7WSL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115474743
gene id: 1415580:LOC115474743
uniprot id: A0A6P7YSK4
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

1415580:LOC115470943
gene id: 1415580:LOC115470943
uniprot id: A0A6P7YC89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the p22phox family.
messages: Cell membrane
messages: Composed of a heavy chain (beta) and a light chain (alpha). Component of an NADPH oxidase complex composed of a heterodimer formed by the membrane proteins CYBA and CYBB and the cytosolic subunits NCF1, NCF2 and NCF4. Interacts with NCF1 (via SH3 domain).
messages: Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
messages: Membrane

1415580:LOC115462541
gene id: 1415580:LOC115462541
uniprot id: A0A6P7X512
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

1415580:PIK3R1
gene id: 1415580:PIK3R1
uniprot id: A0A6P7X0L5
uniprot id: A0A6P7X707
uniprot id: A0A6P7XEK5
uniprot id: A0A6P7XFR4
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

1415580:PPARG
gene id: 1415580:PPARG
uniprot id: A0A6P7Y5Q4
uniprot id: A0A6P7YIH8
uniprot id: A0A6P7YIW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Cytoplasm
messages: Heterodimer with other nuclear receptors.
messages: Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. May play a role in the regulation of circadian rhythm.
messages: Nucleus

1415580:LOC115479534
gene id: 1415580:LOC115479534
uniprot id: A0A6P7ZD85
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

1415580:LOC115474730
gene id: 1415580:LOC115474730
uniprot id: A0A6P7YFK8
uniprot id: A0A6P7YMH2
uniprot id: A0A6P7YSM5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

1415580:LOC115470250
gene id: 1415580:LOC115470250
uniprot id: A0A6P7XUI1
names: Similarity
names: Subunit
messages: Belongs to the SFTPD family.
messages: Oligomeric complex of 4 set of homotrimers.

1415580:GREB1
gene id: 1415580:GREB1
uniprot id: A0A6P7X5Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GREB1 family.
messages: Membrane

1415580:LOC115460566
gene id: 1415580:LOC115460566
uniprot id: A0A6P7WSM9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:DPYD
gene id: 1415580:DPYD
uniprot id: A0A6P7Y889
uniprot id: A0A6P7YDN2
uniprot id: A0A6P7YEB3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.
messages: Binds 4 [4Fe-4S] clusters. Contains approximately 16 iron atoms per subunit.
messages: Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine.

1415580:LOC115460441
gene id: 1415580:LOC115460441
uniprot id: A0A6P7WY37
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1415580:SNX1
gene id: 1415580:SNX1
uniprot id: A0A6P7WTY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: lamellipodium
messages: trans-Golgi network membrane

1415580:LOC115479269
gene id: 1415580:LOC115479269
uniprot id: A0A6P7ZC80
names: Function
names: Similarity
messages: Belongs to the RutC family.
messages: Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase.

1415580:CHD8
gene id: 1415580:CHD8
uniprot id: A0A6P7WX92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. CHD8 subfamily.
messages: Component of some MLL1/MLL complex.
messages: DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive genes. May also act as a transcription activator by participating in efficient U6 RNA polymerase III transcription.
messages: Nucleus

1415580:SLC44A3
gene id: 1415580:SLC44A3
uniprot id: A0A6P7YFD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

1415580:LOC115482005
gene id: 1415580:LOC115482005
uniprot id: A0A6P7ZDF4
uniprot id: A0A6P7ZT46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Secreted

1415580:LOC115464731
gene id: 1415580:LOC115464731
uniprot id: A0A6P7X5R8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LOC115457116
gene id: 1415580:LOC115457116
uniprot id: A0A6P7WVX1
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115462785
gene id: 1415580:LOC115462785
uniprot id: A0A6P7XDF3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cysteine dioxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the oxidation of cysteine to cysteine sulfinic acid with addition of molecular dioxygen.

1415580:LOC115480543
gene id: 1415580:LOC115480543
uniprot id: A0A6P7ZBX0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

1415580:LOC115473352
gene id: 1415580:LOC115473352
uniprot id: A0A6P7YLZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

1415580:ORMDL3
gene id: 1415580:ORMDL3
uniprot id: A0A6P7ZDK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

1415580:REEP3
gene id: 1415580:REEP3
uniprot id: A0A6P7Y1L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

1415580:LOC115467283
gene id: 1415580:LOC115467283
uniprot id: A0A6P7XPA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

1415580:LOC115460254
gene id: 1415580:LOC115460254
uniprot id: A0A6P7WRV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).

1415580:PER2
gene id: 1415580:PER2
uniprot id: A0A6P7Z2H0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

1415580:LRP10
gene id: 1415580:LRP10
uniprot id: A0A6P7WRJ5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:WDR12
gene id: 1415580:WDR12
uniprot id: A0A6P7YTG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat WDR12/YTM1 family.
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

1415580:HM13
gene id: 1415580:HM13
uniprot id: A0A6P7YSH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

1415580:SASS6
gene id: 1415580:SASS6
uniprot id: A0A6P7Y7F0
uniprot id: A0A6P7YET5
names: Subcellular Location Annotation
messages: centrosome

1415580:LOC115473438
gene id: 1415580:LOC115473438
uniprot id: A0A6P7Y9U8
uniprot id: A0A6P7YH12
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selectin/LECAM family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:LOC115468358
gene id: 1415580:LOC115468358
uniprot id: A0A6P7XTN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

1415580:TMEM132D
gene id: 1415580:TMEM132D
uniprot id: A0A6P7ZCN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

1415580:PLD4
gene id: 1415580:PLD4
uniprot id: A0A6P7Z1L1
uniprot id: A0A6P7Z5Y3
names: Similarity
messages: Belongs to the phospholipase D family.

1415580:DEDD
gene id: 1415580:DEDD
uniprot id: A0A6P7WJK3
uniprot id: A0A6P7WSX7
names: Subcellular Location Annotation
messages: nucleolus

1415580:LOC115469252
gene id: 1415580:LOC115469252
uniprot id: A0A6P7XQA8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-1 family.
messages: Lysosome
messages: Monomer.
messages: cytosol
messages: extracellular exosome

1415580:OLFM2
gene id: 1415580:OLFM2
uniprot id: A0A6P7X6C8
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

1415580:SEMA3G
gene id: 1415580:SEMA3G
uniprot id: A0A6P7YA49
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115479887
gene id: 1415580:LOC115479887
uniprot id: A0A6P7ZEM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1415580:NXPH4
gene id: 1415580:NXPH4
uniprot id: A0A6P7XP97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

1415580:DAND5
gene id: 1415580:DAND5
uniprot id: A0A6P7XJT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

1415580:TMEM173
gene id: 1415580:TMEM173
uniprot id: A0A6P7YVD2
uniprot id: A0A6P7YZM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STING family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: autophagosome membrane
messages: perinuclear region

1415580:LOC115466828
gene id: 1415580:LOC115466828
uniprot id: A0A6P7XUT5
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 22 family.
messages: Monomer.

1415580:PPFIBP2
gene id: 1415580:PPFIBP2
uniprot id: A0A6P7XN73
names: Similarity
messages: Belongs to the liprin family. Liprin-beta subfamily.

1415580:DEUP1
gene id: 1415580:DEUP1
uniprot id: A0A6P7XKV5
uniprot id: A0A6P7XSL1
uniprot id: A0A6P7XU48
uniprot id: A0A6P7XU55
uniprot id: A0A6P7XZT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP63 family.
messages: Cytoplasm

1415580:ARPC5
gene id: 1415580:ARPC5
uniprot id: A0A6P7YFN4
names: Function
names: Similarity
messages: Belongs to the ARPC5 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.

1415580:BCL7B
gene id: 1415580:BCL7B
uniprot id: A0A6P7ZG62
uniprot id: A0A6P7ZN40
uniprot id: A0A6P7ZWS2
uniprot id: A0A6P8A0A5
names: Similarity
messages: Belongs to the BCL7 family.

1415580:FKBP4
gene id: 1415580:FKBP4
uniprot id: A0A6P7YZQ3
uniprot id: A0A6P7Z125
uniprot id: A0A6P7Z3X8
names: Subcellular Location Annotation
messages: Nucleus

1415580:PLXNA1
gene id: 1415580:PLXNA1
uniprot id: A0A6P7Y2X1
uniprot id: A0A6P7YAA0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:TFAP2C
gene id: 1415580:TFAP2C
uniprot id: A0A6P7YX95
uniprot id: A0A6P7YXP4
names: Similarity
messages: Belongs to the AP-2 family.

1415580:MRPL11
gene id: 1415580:MRPL11
uniprot id: A0A6P7ZD30
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

1415580:TMEM256
gene id: 1415580:TMEM256
uniprot id: A0A6P7WXZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM256 family.
messages: Membrane

1415580:PSMB6
gene id: 1415580:PSMB6
uniprot id: A0A6P7WPG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

1415580:FAM167B
gene id: 1415580:FAM167B
uniprot id: A0A6P7ZGN3
uniprot id: A0A6P7ZNC7
names: Similarity
messages: Belongs to the FAM167 (SEC) family.

1415580:TLE1
gene id: 1415580:TLE1
uniprot id: A0A6P7X1X2
uniprot id: A0A6P7X1X7
uniprot id: A0A6P7X1Y2
uniprot id: A0A6P7X8C8
uniprot id: A0A6P7XAP3
uniprot id: A0A6P7XAQ0
uniprot id: A0A6P7XFX7
uniprot id: A0A6P7XFY2
uniprot id: A0A6P7XH16
uniprot id: A0A6P7XH21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

1415580:LOC115474109
gene id: 1415580:LOC115474109
uniprot id: A0A6P7YKG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

1415580:LOC115461263
gene id: 1415580:LOC115461263
uniprot id: A0A6P7X9Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:NFIA
gene id: 1415580:NFIA
uniprot id: A0A6P7Y3W2
uniprot id: A0A6P7YAZ2
uniprot id: A0A6P7YGN6
uniprot id: A0A6P7YH31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

1415580:MAEA
gene id: 1415580:MAEA
uniprot id: A0A6P7X6F6
names: Subcellular Location Annotation
messages: Nucleus matrix

1415580:HOXA13
gene id: 1415580:HOXA13
uniprot id: A0A6P7X6P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

1415580:MRPS17
gene id: 1415580:MRPS17
uniprot id: A0A6P7WW18
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

1415580:LOC115481630
gene id: 1415580:LOC115481630
uniprot id: A0A6P7ZFZ1
names: Similarity
messages: Belongs to the GST superfamily. Mu family.

1415580:SLC5A6
gene id: 1415580:SLC5A6
uniprot id: A0A6P7XN07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1415580:PPP1CA
gene id: 1415580:PPP1CA
uniprot id: A0A6P7WUM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: Cytoplasm

1415580:SLC7A7
gene id: 1415580:SLC7A7
uniprot id: A0A6P7WSZ9
names: Subcellular Location Annotation
messages: Membrane

1415580:TRAPPC3
gene id: 1415580:TRAPPC3
uniprot id: A0A6P7ZC43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

1415580:LOC115457639
gene id: 1415580:LOC115457639
uniprot id: A0A6P7WPK5
names: Subcellular Location Annotation
messages: Membrane

1415580:OTUB2
gene id: 1415580:OTUB2
uniprot id: A0A6P7Z498
names: Similarity
messages: Belongs to the peptidase C65 family.

1415580:SS18L1
gene id: 1415580:SS18L1
uniprot id: A0A6P7YTV4
names: Similarity
messages: Belongs to the SS18 family.

1415580:GPR21
gene id: 1415580:GPR21
uniprot id: A0A6P7YDS1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:FAN1
gene id: 1415580:FAN1
uniprot id: A0A6P7X2M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAN1 family.
messages: Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
messages: Nucleus

1415580:EPHB4
gene id: 1415580:EPHB4
uniprot id: A0A6P7WW99
names: Subcellular Location Annotation
messages: Membrane

1415580:NIPSNAP3A
gene id: 1415580:NIPSNAP3A
uniprot id: A0A6P7XHP4
names: Similarity
messages: Belongs to the NipSnap family.

1415580:LOC115472428
gene id: 1415580:LOC115472428
uniprot id: A0A6P7YI39
names: Similarity
messages: Belongs to the peptidase C12 family.

1415580:PLEC
gene id: 1415580:PLEC
uniprot id: A0A6P7ZRU8
names: Subcellular Location Annotation
messages: cytoskeleton

1415580:NME9
gene id: 1415580:NME9
uniprot id: A0A6P7YTU7
names: Similarity
messages: Belongs to the NDK family.

1415580:SLC6A6
gene id: 1415580:SLC6A6
uniprot id: A0A6P7Y1H1
uniprot id: A0A6P7Y8P6
uniprot id: A0A6P7Y8V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A6 subfamily.
messages: Cell membrane
messages: Membrane

1415580:HACD3
gene id: 1415580:HACD3
uniprot id: A0A6P7X672
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:INPP4A
gene id: 1415580:INPP4A
uniprot id: A0A6P7XPG7
uniprot id: A0A6P7XXI3
uniprot id: A0A6P7Y2L4
uniprot id: A0A6P7Y325
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

1415580:TIE1
gene id: 1415580:TIE1
uniprot id: A0A6P7Y841
uniprot id: A0A6P7YEA3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:LOC115466270
gene id: 1415580:LOC115466270
uniprot id: A0A6P7XL96
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Endosome
messages: Heterooligomeric complex.
messages: Membrane

1415580:LOC115482198
gene id: 1415580:LOC115482198
uniprot id: A0A6P7ZEA3
uniprot id: A0A6P7ZEB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

1415580:GRHPR
gene id: 1415580:GRHPR
uniprot id: A0A6P7XA94
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1415580:XKR4
gene id: 1415580:XKR4
uniprot id: A0A6P7Z4D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

1415580:VPS53
gene id: 1415580:VPS53
uniprot id: A0A6P8A0B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS53 family.
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

1415580:LOC115457397
gene id: 1415580:LOC115457397
uniprot id: A0A6P7WXM6
names: Subcellular Location Annotation
messages: Membrane

1415580:TRAM1
gene id: 1415580:TRAM1
uniprot id: A0A6P7Z769
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

1415580:DDX4
gene id: 1415580:DDX4
uniprot id: A0A6P7X6T0
uniprot id: A0A6P7X927
uniprot id: A0A6P7XFJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family.
messages: Cytoplasm

1415580:CWF19L2
gene id: 1415580:CWF19L2
uniprot id: A0A6P7XST8
names: Similarity
messages: Belongs to the CWF19 family.

1415580:CAVIN1
gene id: 1415580:CAVIN1
uniprot id: A0A6P7ZAA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

1415580:LOC115482491
gene id: 1415580:LOC115482491
uniprot id: A0A6P7ZYT0
names: Similarity
messages: Belongs to the peptidase A1 family.

1415580:IL17C
gene id: 1415580:IL17C
uniprot id: A0A6P7Y791
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

1415580:GTF2E2
gene id: 1415580:GTF2E2
uniprot id: A0A6P7XJB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFIIE beta subunit family.
messages: Nucleus
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
messages: Tetramer of two alpha and two beta chains.

1415580:DGKB
gene id: 1415580:DGKB
uniprot id: A0A6P7XX94
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

1415580:SUMO2
gene id: 1415580:SUMO2
uniprot id: A0A6P7YM10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

1415580:LOC115457684
gene id: 1415580:LOC115457684
uniprot id: A0A6P7WPR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

1415580:LOC115470915
gene id: 1415580:LOC115470915
uniprot id: A0A6P7YC42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP10 subfamily.
messages: Cytoplasm
messages: Nucleus

1415580:LOC115471964
gene id: 1415580:LOC115471964
uniprot id: A0A6P7YG30
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calreticulin family.
messages: Endoplasmic reticulum lumen
messages: Monomer.

1415580:ONECUT3
gene id: 1415580:ONECUT3
uniprot id: A0A6P7Z7H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

1415580:LOC115464825
gene id: 1415580:LOC115464825
uniprot id: A0A6P7X619
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ripply family.
messages: Nucleus

1415580:CGA
gene id: 1415580:CGA
uniprot id: A0A6P7XLG4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit alpha family.
messages: Heterodimer of an alpha and a beta chain.
messages: Secreted

1415580:DNAH9
gene id: 1415580:DNAH9
uniprot id: A0A6P7YL81
names: Similarity
messages: Belongs to the dynein heavy chain family.

1415580:SCN1B
gene id: 1415580:SCN1B
uniprot id: A0A6P7YXM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel auxiliary subunit SCN1B (TC 8.A.17) family.
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: axon

1415580:EDC4
gene id: 1415580:EDC4
uniprot id: A0A6P7XVQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat EDC4 family.
messages: P-body

1415580:LOC115460546
gene id: 1415580:LOC115460546
uniprot id: A0A6P7WYE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

1415580:KCNJ4
gene id: 1415580:KCNJ4
uniprot id: A0A6P7YTC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

1415580:LAMTOR2
gene id: 1415580:LAMTOR2
uniprot id: A0A6P7WP07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GAMAD family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

1415580:CDC45
gene id: 1415580:CDC45
uniprot id: A0A6P7ZA60
uniprot id: A0A6P7ZFT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC45 family.
messages: Nucleus

1415580:KATNAL1
gene id: 1415580:KATNAL1
uniprot id: A0A6P7XT45
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
messages: Cytoplasm
messages: Interacts with KATNB1 and KATNBL1.
messages: Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays.
messages: centrosome
messages: cytoskeleton
messages: spindle
messages: spindle pole

1415580:STEAP1
gene id: 1415580:STEAP1
uniprot id: A0A6P7XQZ2
uniprot id: A0A6P7XQZ9
uniprot id: A0A6P7XSP4
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115464482
gene id: 1415580:LOC115464482
uniprot id: A0A6P7XBP6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:METAP1
gene id: 1415580:METAP1
uniprot id: A0A6P7WZM4
uniprot id: A0A6P7X8Y0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

1415580:AKAP5
gene id: 1415580:AKAP5
uniprot id: A0A6P7YVQ9
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115474811
gene id: 1415580:LOC115474811
uniprot id: A0A6P7YP28
names: Function
names: Similarity
messages: Belongs to the TMEM177 family.
messages: Plays a role in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation and is required for the stabilization of COX20 and the newly synthesized MT-CO2/COX2 protein.

1415580:LHX5
gene id: 1415580:LHX5
uniprot id: A0A6P7ZGW1
names: Subcellular Location Annotation
messages: Nucleus

1415580:KPNB1
gene id: 1415580:KPNB1
uniprot id: A0A6P7ZMY2
uniprot id: A0A6P7ZTL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the importin beta family. Importin beta-1 subfamily.
messages: Cytoplasm

1415580:TMEM159
gene id: 1415580:TMEM159
uniprot id: A0A6P7YUS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LDAF1 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Membrane

1415580:PSMD2
gene id: 1415580:PSMD2
uniprot id: A0A6P7YY72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S2 family.
messages: Binds to the intracellular domain of tumor necrosis factor type 1 receptor. The binding domain of TRAP1 and TRAP2 resides outside the death domain of TNFR1.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

1415580:FAM162A
gene id: 1415580:FAM162A
uniprot id: A0A6P7Y414
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0389 family.
messages: Membrane

1415580:SMIM7
gene id: 1415580:SMIM7
uniprot id: A0A6P7ZPC1
names: Similarity
messages: Belongs to the SMIM7 family.

1415580:GDPGP1
gene id: 1415580:GDPGP1
uniprot id: A0A6P7X800
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDPGP1 family.
messages: Cytoplasm
messages: Specific and highly efficient GDP-D-glucose phosphorylase regulating the levels of GDP-D-glucose in cells.

1415580:LOC115456667
gene id: 1415580:LOC115456667
uniprot id: A0A6P7WU59
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1415580:LOC115457410
gene id: 1415580:LOC115457410
uniprot id: A0A6P7WQP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115462826
gene id: 1415580:LOC115462826
uniprot id: A0A6P7XDM8
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1415580:LOC115472007
gene id: 1415580:LOC115472007
uniprot id: A0A6P7YFM5
uniprot id: A0A6P7YG98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

1415580:SS18L2
gene id: 1415580:SS18L2
uniprot id: A0A6P7Y5N0
names: Similarity
messages: Belongs to the SS18 family.

1415580:BNIP1
gene id: 1415580:BNIP1
uniprot id: A0A6P7YWJ7
names: Subcellular Location Annotation
messages: Membrane

1415580:CPNE3
gene id: 1415580:CPNE3
uniprot id: A0A6P7Z3Z1
names: Similarity
messages: Belongs to the copine family.

1415580:FAM219B
gene id: 1415580:FAM219B
uniprot id: A0A6P7WGS1
uniprot id: A0A6P7WGT6
uniprot id: A0A6P7WX11
names: Similarity
messages: Belongs to the FAM219 family.

1415580:LOC115460578
gene id: 1415580:LOC115460578
uniprot id: A0A6P7X6J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:CFLAR
gene id: 1415580:CFLAR
uniprot id: A0A6P7YHQ0
uniprot id: A0A6P7YMZ0
names: Similarity
messages: Belongs to the peptidase C14A family.

1415580:PTGIR
gene id: 1415580:PTGIR
uniprot id: A0A6P7Z9A0
uniprot id: A0A6P7ZDQ9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:LOC115468677
gene id: 1415580:LOC115468677
uniprot id: A0A6P7Y0U5
uniprot id: A0A6P7Y0V4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1415580:IP6K2
gene id: 1415580:IP6K2
uniprot id: A0A6P7YDC7
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

1415580:DCTN6
gene id: 1415580:DCTN6
uniprot id: A0A6P7XI97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.
messages: cytoskeleton

1415580:CSNK2B
gene id: 1415580:CSNK2B
uniprot id: A0A6P7XCP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Participates in Wnt signaling.
messages: Tetramer of two alpha and two beta subunits.

1415580:LOC115473845
gene id: 1415580:LOC115473845
uniprot id: A0A6P7YBI3
uniprot id: A0A6P7YIM0
uniprot id: A0A6P7YIX3
uniprot id: A0A6P7YP60
names: Similarity
messages: Belongs to the FAM122 family.

1415580:LOC115460520
gene id: 1415580:LOC115460520
uniprot id: A0A6P7X0Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:TNFRSF11A
gene id: 1415580:TNFRSF11A
uniprot id: A0A6P7Y1W8
uniprot id: A0A6P7Y1X4
uniprot id: A0A6P7Y2N7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115473084
gene id: 1415580:LOC115473084
uniprot id: A0A6P7YKG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Mitochondrion inner membrane
messages: Probably involved in the biogenesis of the COX complex.

1415580:SORL1
gene id: 1415580:SORL1
uniprot id: A0A6P7ZEP0
uniprot id: A0A6P7ZPT2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS10-related sortilin family. SORL1 subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Recycling endosome membrane
messages: Secreted
messages: multivesicular body membrane
messages: secretory vesicle membrane
messages: trans-Golgi network membrane

1415580:SCRN2
gene id: 1415580:SCRN2
uniprot id: A0A6P7ZDH6
uniprot id: A0A6P7ZT92
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

1415580:LOC115475142
gene id: 1415580:LOC115475142
uniprot id: A0A6P7YPT6
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Photoreceptor inner segment
messages: Plays a role in the formation and organization of tight junctions during the establishment of polarity in epithelial cells.

1415580:UNKL
gene id: 1415580:UNKL
uniprot id: A0A6P7YNR7
uniprot id: A0A6P7YWI0
uniprot id: A0A6P7YZN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unkempt family.
messages: Cytoplasm

1415580:LOC115465213
gene id: 1415580:LOC115465213
uniprot id: A0A6P7XE27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115461983
gene id: 1415580:LOC115461983
uniprot id: A0A6P7WXE7
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

1415580:THAP4
gene id: 1415580:THAP4
uniprot id: A0A6P7Z5E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THAP1 family.
messages: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes.
messages: nucleoplasm

1415580:FAM228B
gene id: 1415580:FAM228B
uniprot id: A0A6P7XL00
names: Similarity
messages: Belongs to the FAM228 family.

1415580:LOC115481349
gene id: 1415580:LOC115481349
uniprot id: A0A6P7ZLL5
names: Subcellular Location Annotation
messages: autophagosome

1415580:LOC115464527
gene id: 1415580:LOC115464527
uniprot id: A0A6P7XKD4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:SMARCA1
gene id: 1415580:SMARCA1
uniprot id: A0A6P7YTE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

1415580:DAO
gene id: 1415580:DAO
uniprot id: A0A6P7Z1A4
uniprot id: A0A6P7ZBT6
uniprot id: A0A6P7ZCP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

1415580:SNCA
gene id: 1415580:SNCA
uniprot id: A0A6P7X7J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synuclein family.
messages: Membrane
messages: Nucleus
messages: Secreted
messages: Synapse

1415580:LOC115463409
gene id: 1415580:LOC115463409
uniprot id: A0A6P7XHI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:FA2H
gene id: 1415580:FA2H
uniprot id: A0A6P7XVN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sterol desaturase family. SCS7 subfamily.
messages: Binds 2 Zn(2+) ions per subunit that likely form a catalytic dimetal center.
messages: Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters in sebaceous gland, specifically regulating hair follicle homeostasis. Involved in the synthesis of sphingolipids of plasma membrane rafts, controlling lipid raft mobility and trafficking of raft-associated proteins.
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:PTCD3
gene id: 1415580:PTCD3
uniprot id: A0A6P7WUT8
uniprot id: A0A6P7X9X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS39 family.
messages: Mitochondrion

1415580:MNS1
gene id: 1415580:MNS1
uniprot id: A0A6P7X6Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MNS1 family.
messages: Nucleus
messages: cilium axoneme
messages: flagellum axoneme

1415580:TNS1
gene id: 1415580:TNS1
uniprot id: A0A6P7YI75
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

1415580:LOC115465717
gene id: 1415580:LOC115465717
uniprot id: A0A6P7XPG9
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

1415580:LOC115472974
gene id: 1415580:LOC115472974
uniprot id: A0A6P7YJZ8
names: Similarity
messages: Belongs to the GORAB family.

1415580:LOC115464734
gene id: 1415580:LOC115464734
uniprot id: A0A6P7XKV3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:ALG5
gene id: 1415580:ALG5
uniprot id: A0A6P7XZV3
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

1415580:TM4SF18
gene id: 1415580:TM4SF18
uniprot id: A0A6P7Z7Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

1415580:LOC115458281
gene id: 1415580:LOC115458281
uniprot id: A0A6P7X0D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine).

1415580:GPR12
gene id: 1415580:GPR12
uniprot id: A0A6P7XQ59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:APIP
gene id: 1415580:APIP
uniprot id: A0A6P7XMP8
uniprot id: A0A6P7XVV6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aldolase class II family. Adducin subfamily.
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis.
messages: Cytoplasm

1415580:TRMT2B
gene id: 1415580:TRMT2B
uniprot id: A0A6P7YED0
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:SLC44A4
gene id: 1415580:SLC44A4
uniprot id: A0A6P7XR74
uniprot id: A0A6P7XRU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

1415580:LOC115462827
gene id: 1415580:LOC115462827
uniprot id: A0A6P7WZL6
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1415580:ANKRD13A
gene id: 1415580:ANKRD13A
uniprot id: A0A6P7ZJW4
uniprot id: A0A6P7ZM30
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115458186
gene id: 1415580:LOC115458186
uniprot id: A0A6P7WKN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:PRDM13
gene id: 1415580:PRDM13
uniprot id: A0A6P7XCT7
names: Subcellular Location Annotation
messages: Nucleus

1415580:PFKFB1
gene id: 1415580:PFKFB1
uniprot id: A0A6P7X2V5
uniprot id: A0A6P7X9B0
uniprot id: A0A6P7XBM8
uniprot id: A0A6P7XGV9
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

1415580:CNN1
gene id: 1415580:CNN1
uniprot id: A0A6P7XB89
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

1415580:LOC115456678
gene id: 1415580:LOC115456678
uniprot id: A0A6P7WL87
names: Subcellular Location Annotation
messages: Membrane

1415580:DDX21
gene id: 1415580:DDX21
uniprot id: A0A6P7Y2G5
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.

1415580:HAPLN2
gene id: 1415580:HAPLN2
uniprot id: A0A6P7WWW6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115466450
gene id: 1415580:LOC115466450
uniprot id: A0A6P7XJZ4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:SPNS2
gene id: 1415580:SPNS2
uniprot id: A0A6P7WL58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

1415580:LOC115471159
gene id: 1415580:LOC115471159
uniprot id: A0A6P7Y6W1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:SERPINB1
gene id: 1415580:SERPINB1
uniprot id: A0A6P7YU72
names: Similarity
messages: Belongs to the serpin family. Ov-serpin subfamily.

1415580:LOC115480152
gene id: 1415580:LOC115480152
uniprot id: A0A6P7ZAB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

1415580:RRAGA
gene id: 1415580:RRAGA
uniprot id: A0A6P7YQQ5
uniprot id: A0A6P7YR07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

1415580:LOC115466327
gene id: 1415580:LOC115466327
uniprot id: A0A6P7XCS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

1415580:SERPINF2
gene id: 1415580:SERPINF2
uniprot id: A0A6P7ZXL6
names: Similarity
messages: Belongs to the serpin family.

1415580:SLC25A17
gene id: 1415580:SLC25A17
uniprot id: A0A6P7XTP8
uniprot id: A0A6P7Y7R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1415580:CDC14A
gene id: 1415580:CDC14A
uniprot id: A0A6P7Y9B7
uniprot id: A0A6P7YEU2
uniprot id: A0A6P7YFH6
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

1415580:SRD5A2
gene id: 1415580:SRD5A2
uniprot id: A0A6P7XMB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane
messages: Microsome membrane

1415580:CDC42BPB
gene id: 1415580:CDC42BPB
uniprot id: A0A6P7Z3W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
messages: lamellipodium

1415580:GATAD1
gene id: 1415580:GATAD1
uniprot id: A0A6P7XL60
names: Subcellular Location Annotation
messages: Nucleus

1415580:MRPL43
gene id: 1415580:MRPL43
uniprot id: A0A6P7XZ40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL43 family.
messages: Mitochondrion

1415580:LOC115466176
gene id: 1415580:LOC115466176
uniprot id: A0A6P7XC20
uniprot id: A0A6P7XIT9
names: Similarity
messages: Belongs to the MHC class I family.

1415580:LOC115466315
gene id: 1415580:LOC115466315
uniprot id: A0A6P7XJI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Membrane

1415580:SNRNP200
gene id: 1415580:SNRNP200
uniprot id: A0A6P7XX04
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

1415580:LOC115480516
gene id: 1415580:LOC115480516
uniprot id: A0A6P7Z6Y3
uniprot id: A0A6P7ZFE5
uniprot id: A0A6P7ZIV5
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

1415580:LOC115458003
gene id: 1415580:LOC115458003
uniprot id: A0A6P7WJV8
uniprot id: A0A6P7WT70
uniprot id: A0A6P7X0D8
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:DGUOK
gene id: 1415580:DGUOK
uniprot id: A0A6P7Y3P3
names: Similarity
messages: Belongs to the DCK/DGK family.

1415580:RPSA
gene id: 1415580:RPSA
uniprot id: A0A6P7Y5H8
uniprot id: A0A6P7YIA8
names: Caution
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acylated. Acylation may be a prerequisite for conversion of the monomeric 37 kDa laminin receptor precursor (37LRP) to the mature dimeric 67 kDa laminin receptor (67LR), and may provide a mechanism for membrane association.
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Cell membrane
messages: Cleaved by stromelysin-3 (ST3) at the cell surface. Cleavage by stromelysin-3 may be a mechanism to alter cell-extracellular matrix interactions.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer (37LRP) and homodimer (67LR). Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Interacts with RPS21. Interacts with several laminins including at least LAMB1. Interacts with MDK.
messages: Nucleus
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis.
messages: This protein appears to have acquired a second function as a laminin receptor specifically in the vertebrate lineage.

1415580:ITPKC
gene id: 1415580:ITPKC
uniprot id: A0A6P7ZAD9
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

1415580:ZPBP2
gene id: 1415580:ZPBP2
uniprot id: A0A6P7ZUU4
uniprot id: A0A6P7ZVK2
uniprot id: A0A6P7ZWI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the zona pellucida-binding protein Sp38 family.
messages: Secreted

1415580:VPS33A
gene id: 1415580:VPS33A
uniprot id: A0A6P7Z5A4
uniprot id: A0A6P7ZDC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

1415580:RHPN1
gene id: 1415580:RHPN1
uniprot id: A0A6P7X0S4
names: Similarity
messages: Belongs to the RHPN family.

1415580:TALDO1
gene id: 1415580:TALDO1
uniprot id: A0A6P7Y296
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.

1415580:NR0B2
gene id: 1415580:NR0B2
uniprot id: A0A6P7ZDT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus

1415580:LOC115460315
gene id: 1415580:LOC115460315
uniprot id: A0A6P7WS10
uniprot id: A0A6P7X0E2
names: Subcellular Location Annotation
messages: cilium basal body

1415580:ARL2
gene id: 1415580:ARL2
uniprot id: A0A6P7ZFV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

1415580:TACC3
gene id: 1415580:TACC3
uniprot id: A0A6P7XD04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

1415580:LOC115481912
gene id: 1415580:LOC115481912
uniprot id: A0A6P7ZHF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:ADAM12
gene id: 1415580:ADAM12
uniprot id: A0A6P7XTN7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115468369
gene id: 1415580:LOC115468369
uniprot id: A0A6P7XS21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1415580:LOC115470017
gene id: 1415580:LOC115470017
uniprot id: A0A6P7Y1L7
uniprot id: A0A6P7Y6H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prominin family.
messages: Membrane
messages: microvillus membrane

1415580:GPR89B
gene id: 1415580:GPR89B
uniprot id: A0A6P7Y985
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Golgi pH regulator (TC 1.A.38) family.
messages: Membrane

1415580:LOC115468532
gene id: 1415580:LOC115468532
uniprot id: A0A6P7XUK0
uniprot id: A0A6P7XZL9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1415580:MED1
gene id: 1415580:MED1
uniprot id: A0A6P7ZTY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 1 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

1415580:LOC115468302
gene id: 1415580:LOC115468302
uniprot id: A0A6P7XRU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LHCGR
gene id: 1415580:LHCGR
uniprot id: A0A6P7XGV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

1415580:VPS37C
gene id: 1415580:VPS37C
uniprot id: A0A6P7ZFU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

1415580:TPD52
gene id: 1415580:TPD52
uniprot id: A0A6P7Z515
uniprot id: A0A6P7Z7M8
uniprot id: A0A6P7Z7N8
names: Similarity
messages: Belongs to the TPD52 family.

1415580:LOC115471061
gene id: 1415580:LOC115471061
uniprot id: A0A6P7YC17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

1415580:SEMA4C
gene id: 1415580:SEMA4C
uniprot id: A0A6P7XQ80
uniprot id: A0A6P7XX29
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:ABCG2
gene id: 1415580:ABCG2
uniprot id: A0A6P7WTM9
uniprot id: A0A6P7WZG6
uniprot id: A0A6P7X229
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Cell membrane
messages: Membrane
messages: Mitochondrion membrane

1415580:NAMPT
gene id: 1415580:NAMPT
uniprot id: A0A6P7Z5A8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAPRTase family.
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Secreted

1415580:PIGH
gene id: 1415580:PIGH
uniprot id: A0A6P7Z1Z9
uniprot id: A0A6P7Z4T2
names: Similarity
messages: Belongs to the PIGH family.

1415580:TBRG1
gene id: 1415580:TBRG1
uniprot id: A0A6P7Z5S0
names: Subcellular Location Annotation
messages: Nucleus

1415580:KCND3
gene id: 1415580:KCND3
uniprot id: A0A6P7ZEK8
uniprot id: A0A6P7ZUW2
uniprot id: A0A6P7ZWL2
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

1415580:LOC115464422
gene id: 1415580:LOC115464422
uniprot id: A0A6P7XJ37
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LOC115472395
gene id: 1415580:LOC115472395
uniprot id: A0A6P7YC76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer and heterodimer with SSTR3 and SSTR5. Heterodimerization with SSTR3 inactivates SSTR3 receptor function. Heterodimerization with SSTR5 is enhanced by agonist stimulation of SSTR2 and increases SSTR2 cell growth inhibition activity. Following agonist stimulation, homodimers dissociate into monomers which is required for receptor internalization. Interacts with beta-arrestin; this interaction is necessary for receptor internalization and is destabilized by heterodimerization with SSTR5 which results in increased recycling of SSTR2 to the cell surface. Interacts (via C-terminus) with SHANK1 (via PDZ domain).
messages: Membrane
messages: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

1415580:KMT2D
gene id: 1415580:KMT2D
uniprot id: A0A6P7XJL7
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115463477
gene id: 1415580:LOC115463477
uniprot id: A0A6P7XGT6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:LOC115482025
gene id: 1415580:LOC115482025
uniprot id: A0A6P7ZIE9
uniprot id: A0A6P7ZV38
names: Subcellular Location Annotation
messages: Cytoplasm

1415580:CD36
gene id: 1415580:CD36
uniprot id: A0A6P7Z3M8
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the CD36 family.
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane
messages: Membrane raft

1415580:LOC115466308
gene id: 1415580:LOC115466308
uniprot id: A0A6P7XCP5
uniprot id: A0A6P7XLF0
uniprot id: A0A6P7XSE6
uniprot id: A0A6P7XSF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

1415580:XPR1
gene id: 1415580:XPR1
uniprot id: A0A6P7YD08
uniprot id: A0A6P7YIC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYG1 (TC 2.A.94) family.
messages: Membrane

1415580:LOC115468711
gene id: 1415580:LOC115468711
uniprot id: A0A6P7Y0D9
uniprot id: A0A6P7Y0Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

1415580:LOC115476334
gene id: 1415580:LOC115476334
uniprot id: A0A6P7YZ13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

1415580:KAT7
gene id: 1415580:KAT7
uniprot id: A0A6P7ZC62
uniprot id: A0A6P7ZGA1
uniprot id: A0A6P7ZQ50
uniprot id: A0A6P7ZUZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

1415580:DDX3X
gene id: 1415580:DDX3X
uniprot id: A0A6P7XS27
uniprot id: A0A6P7XZ97
uniprot id: A0A6P7Y063
uniprot id: A0A6P7Y518
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family.
messages: Cytoplasm

1415580:SRFBP1
gene id: 1415580:SRFBP1
uniprot id: A0A6P7X1G8
uniprot id: A0A6P7XA66
names: Function
messages: May be involved in regulating transcriptional activation of cardiac genes during the aging process. May play a role in biosynthesis and/or processing of SLC2A4 in adipose cells.

1415580:SMOC2
gene id: 1415580:SMOC2
uniprot id: A0A6P7XIS6
uniprot id: A0A6P7XPR6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:PARVA
gene id: 1415580:PARVA
uniprot id: A0A6P7XWD9
uniprot id: A0A6P7Y1X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parvin family.
messages: cytoskeleton

1415580:TBP
gene id: 1415580:TBP
uniprot id: A0A6P7XH94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

1415580:LOC115461372
gene id: 1415580:LOC115461372
uniprot id: A0A6P7X0V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PRP19 family.
messages: Homotetramer.
messages: Lipid droplet
messages: Nucleus
messages: Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.

1415580:ENTPD2
gene id: 1415580:ENTPD2
uniprot id: A0A6P7YCV9
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

1415580:EGFR
gene id: 1415580:EGFR
uniprot id: A0A6P7XW44
uniprot id: A0A6P7Y9Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

1415580:HOMER3
gene id: 1415580:HOMER3
uniprot id: A0A6P7ZGF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

1415580:CLIC5
gene id: 1415580:CLIC5
uniprot id: A0A6P7XQ13
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

1415580:LOC115467822
gene id: 1415580:LOC115467822
uniprot id: A0A6P7XPU7
names: Similarity
messages: Belongs to the folate receptor family.

1415580:MTERF3
gene id: 1415580:MTERF3
uniprot id: A0A6P7Z0F7
uniprot id: A0A6P7Z5U5
names: Similarity
messages: Belongs to the mTERF family.

1415580:LOC115480387
gene id: 1415580:LOC115480387
uniprot id: A0A6P7ZEL2
uniprot id: A0A6P7ZIJ3
names: Similarity
messages: Belongs to the peptidase C1 family.

1415580:LOC115475067
gene id: 1415580:LOC115475067
uniprot id: A0A6P7YGV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

1415580:PDE8B
gene id: 1415580:PDE8B
uniprot id: A0A6P7X498
uniprot id: A0A6P7XC37
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

1415580:DNAH2
gene id: 1415580:DNAH2
uniprot id: A0A6P7WWK3
names: Similarity
messages: Belongs to the dynein heavy chain family.

1415580:LOC115479061
gene id: 1415580:LOC115479061
uniprot id: A0A6P7ZB64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAIF1 family.
messages: Induces apoptosis.
messages: Nucleus

1415580:LOC115457774
gene id: 1415580:LOC115457774
uniprot id: A0A6P7WZ80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

1415580:CPEB3
gene id: 1415580:CPEB3
uniprot id: A0A6P7XTS8
names: Similarity
messages: Belongs to the RRM CPEB family.

1415580:TMEM9B
gene id: 1415580:TMEM9B
uniprot id: A0A6P7XNE5
uniprot id: A0A6P7XWI0
names: Similarity
messages: Belongs to the TMEM9 family.

1415580:LOC115482077
gene id: 1415580:LOC115482077
uniprot id: A0A6P7ZTS1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1415580:LOC115471762
gene id: 1415580:LOC115471762
uniprot id: A0A6P7YF30
names: Subcellular Location Annotation
messages: Membrane

1415580:SLC7A10
gene id: 1415580:SLC7A10
uniprot id: A0A6P7Y5R3
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115466268
gene id: 1415580:LOC115466268
uniprot id: A0A6P7XJA8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Endosome
messages: Heterooligomeric complex.
messages: Membrane

1415580:LOC115473804
gene id: 1415580:LOC115473804
uniprot id: A0A6P7YBD5
uniprot id: A0A6P7YP07
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1415580:LTB4R2
gene id: 1415580:LTB4R2
uniprot id: A0A6P7WTU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:APLNR
gene id: 1415580:APLNR
uniprot id: A0A6P7ZG87
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:NKX2-8
gene id: 1415580:NKX2-8
uniprot id: A0A6P7YX62
names: Subcellular Location Annotation
messages: Nucleus

1415580:TGFA
gene id: 1415580:TGFA
uniprot id: A0A6P7XQU0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:GANC
gene id: 1415580:GANC
uniprot id: A0A6P7YZB4
uniprot id: A0A6P7Z3G9
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1415580:LOC115475728
gene id: 1415580:LOC115475728
uniprot id: A0A6P7YW70
names: Similarity
messages: Belongs to the cytochrome P450 family.

1415580:KIF2A
gene id: 1415580:KIF2A
uniprot id: A0A6P7XFM0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

1415580:PPP4C
gene id: 1415580:PPP4C
uniprot id: A0A6P7YL58
names: Similarity
messages: Belongs to the PPP phosphatase family.

1415580:LOC115481926
gene id: 1415580:LOC115481926
uniprot id: A0A6P7ZD45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:ESRP2
gene id: 1415580:ESRP2
uniprot id: A0A6P7Y560
uniprot id: A0A6P7Y5E3
uniprot id: A0A6P7YAU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESRP family.
messages: Nucleus

1415580:APTX
gene id: 1415580:APTX
uniprot id: A0A6P7X3M9
uniprot id: A0A6P7XA63
names: Subcellular Location Annotation
messages: nucleolus
messages: nucleoplasm

1415580:REN
gene id: 1415580:REN
uniprot id: A0A6P7ZCN0
uniprot id: A0A6P7ZGS3
names: Similarity
messages: Belongs to the peptidase A1 family.

1415580:ARV1
gene id: 1415580:ARV1
uniprot id: A0A6P7XNT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARV1 family.
messages: Endoplasmic reticulum membrane
messages: Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.
messages: Membrane

1415580:LOC115480189
gene id: 1415580:LOC115480189
uniprot id: A0A6P7ZDH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

1415580:LOC115482215
gene id: 1415580:LOC115482215
uniprot id: A0A6P7ZED7
names: Similarity
messages: Belongs to the intermediate filament family.

1415580:LPAR1
gene id: 1415580:LPAR1
uniprot id: A0A6P7XAU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cell surface
messages: Endosome
messages: Membrane

1415580:ANO6
gene id: 1415580:ANO6
uniprot id: A0A6P7Z0F3
uniprot id: A0A6P7Z5U9
uniprot id: A0A6P7Z899
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

1415580:LOC115457021
gene id: 1415580:LOC115457021
uniprot id: A0A6P7WMK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:TMED2
gene id: 1415580:TMED2
uniprot id: A0A6P7ZCV3
uniprot id: A0A6P7ZG00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

1415580:LOC115472551
gene id: 1415580:LOC115472551
uniprot id: A0A6P7Y5A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1415580:DNMT1
gene id: 1415580:DNMT1
uniprot id: A0A6P7XBJ0
uniprot id: A0A6P7XKD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

1415580:RAD9B
gene id: 1415580:RAD9B
uniprot id: A0A6P7Z4B6
names: Similarity
messages: Belongs to the rad9 family.

1415580:PPP1R12A
gene id: 1415580:PPP1R12A
uniprot id: A0A6P7YZF3
uniprot id: A0A6P7Z2A5
uniprot id: A0A6P7Z364
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: PP1 comprises a catalytic subunit, and one or several targeting or regulatory subunits.

1415580:NAPG
gene id: 1415580:NAPG
uniprot id: A0A6P7YXT9
names: Similarity
messages: Belongs to the SNAP family.

1415580:PROX1
gene id: 1415580:PROX1
uniprot id: A0A6P7XFD2
names: Subcellular Location Annotation
messages: Nucleus

1415580:NPFFR1
gene id: 1415580:NPFFR1
uniprot id: A0A6P7Y3E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

1415580:IL10RB
gene id: 1415580:IL10RB
uniprot id: A0A6P7XZN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tissue factor family.
messages: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
messages: Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.

1415580:LOC115464646
gene id: 1415580:LOC115464646
uniprot id: A0A6P7XC97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115457362
gene id: 1415580:LOC115457362
uniprot id: A0A6P7WXI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115470111
gene id: 1415580:LOC115470111
uniprot id: A0A6P7XTW1
uniprot id: A0A6P7Y245
names: Subcellular Location Annotation
messages: Cytoplasm

1415580:LOC115482158
gene id: 1415580:LOC115482158
uniprot id: A0A6P7ZW64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115482386
gene id: 1415580:LOC115482386
uniprot id: A0A6P7ZVX6
names: Similarity
messages: Belongs to the N-CoR nuclear receptor corepressors family.

1415580:LOC115457319
gene id: 1415580:LOC115457319
uniprot id: A0A6P7WQE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115475809
gene id: 1415580:LOC115475809
uniprot id: A0A6P7YWC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

1415580:LOC115480232
gene id: 1415580:LOC115480232
uniprot id: A0A6P7Z5L5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fibrillin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

1415580:ZDHHC21
gene id: 1415580:ZDHHC21
uniprot id: A0A6P7XCH8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

1415580:BSN
gene id: 1415580:BSN
uniprot id: A0A6P7YC58
names: Subcellular Location Annotation
messages: Presynaptic active zone

1415580:CDH24
gene id: 1415580:CDH24
uniprot id: A0A6P7WXF8
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

1415580:LOC115474338
gene id: 1415580:LOC115474338
uniprot id: A0A6P7YDT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

1415580:SRM
gene id: 1415580:SRM
uniprot id: A0A6P7WVB1
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

1415580:ZNF706
gene id: 1415580:ZNF706
uniprot id: A0A6P7ZD19
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

1415580:PRKAB2
gene id: 1415580:PRKAB2
uniprot id: A0A6P7YE48
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

1415580:PLXNB1
gene id: 1415580:PLXNB1
uniprot id: A0A6P7YFI8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:SLC44A5
gene id: 1415580:SLC44A5
uniprot id: A0A6P7Y2E0
uniprot id: A0A6P7Y9I6
uniprot id: A0A6P7Y9Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

1415580:LOC115461131
gene id: 1415580:LOC115461131
uniprot id: A0A6P7WTU2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1415580:BMP5
gene id: 1415580:BMP5
uniprot id: A0A6P7XNZ4
names: Similarity
messages: Belongs to the TGF-beta family.

1415580:SLC19A1
gene id: 1415580:SLC19A1
uniprot id: A0A6P7YPZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

1415580:VPS41
gene id: 1415580:VPS41
uniprot id: A0A6P7Y9S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS41 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways.
messages: Vesicle
messages: clathrin-coated vesicle
messages: trans-Golgi network

1415580:LOC115457191
gene id: 1415580:LOC115457191
uniprot id: A0A6P7WW42
names: Subcellular Location Annotation
messages: Membrane

1415580:SYVN1
gene id: 1415580:SYVN1
uniprot id: A0A6P7Z9U0
uniprot id: A0A6P7ZFF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRD1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:ST14
gene id: 1415580:ST14
uniprot id: A0A6P7ZW82
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Degrades extracellular matrix.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:FAAH2
gene id: 1415580:FAAH2
uniprot id: A0A6P7YSM0
names: Similarity
messages: Belongs to the amidase family.

1415580:AK6
gene id: 1415580:AK6
uniprot id: A0A6P7XEV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation.
messages: Cajal body
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer and homodimer. Interacts with COIL (via C-terminus).
messages: nucleoplasm

1415580:PGM3
gene id: 1415580:PGM3
uniprot id: A0A6P7XQZ1
uniprot id: A0A6P7XWV1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O-glycosylation.

1415580:LOC115461110
gene id: 1415580:LOC115461110
uniprot id: A0A6P7WTU7
names: Subcellular Location Annotation
messages: Membrane

1415580:EIF3E
gene id: 1415580:EIF3E
uniprot id: A0A6P7Z3M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit E family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm
messages: Nucleus

1415580:LOC115462374
gene id: 1415580:LOC115462374
uniprot id: A0A6P7WYB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:TMEM19
gene id: 1415580:TMEM19
uniprot id: A0A6P7YSE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

1415580:LOC115482654
gene id: 1415580:LOC115482654
uniprot id: A0A6P7ZGN8
uniprot id: A0A6P7ZNM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Catalyzes the deimination of arginine residues of proteins.
messages: Cytoplasm

1415580:RAB33B
gene id: 1415580:RAB33B
uniprot id: A0A6P7X2I1
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

1415580:LOC115466343
gene id: 1415580:LOC115466343
uniprot id: A0A6P7XJM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

1415580:DLST
gene id: 1415580:DLST
uniprot id: A0A6P7Z2A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Mitochondrion matrix

1415580:CCNF
gene id: 1415580:CCNF
uniprot id: A0A6P7YNW6
uniprot id: A0A6P7YWM6
uniprot id: A0A6P7Z0H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family.
messages: centriole
messages: perinuclear region

1415580:LOC115478725
gene id: 1415580:LOC115478725
uniprot id: A0A6P7YYD0
names: Similarity
messages: Belongs to the SCO1/2 family.

1415580:LOC115456687
gene id: 1415580:LOC115456687
uniprot id: A0A6P7WL97
uniprot id: A0A6P7WU82
uniprot id: A0A6P7WV94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

1415580:LOC115475050
gene id: 1415580:LOC115475050
uniprot id: A0A6P7YNP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:BSG
gene id: 1415580:BSG
uniprot id: A0A6P7ZA99
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Lateral cell membrane

1415580:RARG
gene id: 1415580:RARG
uniprot id: A0A6P7XER5
uniprot id: A0A6P7XNA3
uniprot id: A0A6P7XUA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

1415580:GET1
gene id: 1415580:GET1
uniprot id: A0A6P7Y3K9
uniprot id: A0A6P7Y9C5
uniprot id: A0A6P7YA32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WRB/GET1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:DENND10
gene id: 1415580:DENND10
uniprot id: A0A6P7Y5U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND10 family.
messages: Endosome
messages: Late endosome

1415580:LOC115477765
gene id: 1415580:LOC115477765
uniprot id: A0A6P7Z5B9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Secreted

1415580:CHMP4A
gene id: 1415580:CHMP4A
uniprot id: A0A6P7WSH3
names: Similarity
messages: Belongs to the SNF7 family.

1415580:LOC115458036
gene id: 1415580:LOC115458036
uniprot id: A0A6P7WTC8
names: Similarity
messages: Belongs to the NXPE family.

1415580:SSTR4
gene id: 1415580:SSTR4
uniprot id: A0A6P7XC35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:RNF170
gene id: 1415580:RNF170
uniprot id: A0A6P7X406
uniprot id: A0A6P7XI52
uniprot id: A0A6P7XJ85
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:SEC24B
gene id: 1415580:SEC24B
uniprot id: A0A6P7WU20
uniprot id: A0A6P7WZU4
uniprot id: A0A6P7X2H5
uniprot id: A0A6P7X969
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

1415580:IL17REL
gene id: 1415580:IL17REL
uniprot id: A0A6P7Z9H5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:AMPD3
gene id: 1415580:AMPD3
uniprot id: A0A6P7XXC7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1415580:LOC115464509
gene id: 1415580:LOC115464509
uniprot id: A0A6P7XJB0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:FAM172A
gene id: 1415580:FAM172A
uniprot id: A0A6P7X130
uniprot id: A0A6P7X9S3
uniprot id: A0A6P7XG73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM172 family.
messages: Cytoplasm
messages: Nucleus

1415580:LOC115477101
gene id: 1415580:LOC115477101
uniprot id: A0A6P7YQP0
names: Similarity
messages: Belongs to the SEC6 family.

1415580:GPSM1
gene id: 1415580:GPSM1
uniprot id: A0A6P7YKF9
names: Similarity
messages: Belongs to the GPSM family.

1415580:LOC115461133
gene id: 1415580:LOC115461133
uniprot id: A0A6P7X297
uniprot id: A0A6P7X8Z2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1415580:CFAP45
gene id: 1415580:CFAP45
uniprot id: A0A6P7X0J7
uniprot id: A0A6P7X1Q4
names: Similarity
messages: Belongs to the CFAP45 family.

1415580:DMAC2L
gene id: 1415580:DMAC2L
uniprot id: A0A6P7Z644
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP synthase subunit s family.
messages: Homotetramer. Associates with ATP synthase.
messages: Involved in regulation of mitochondrial membrane ATP synthase. Necessary for H(+) conduction of ATP synthase. Facilitates energy-driven catalysis of ATP synthesis by blocking a proton leak through an alternative proton exit pathway.
messages: Membrane
messages: Mitochondrion inner membrane

1415580:HNMT
gene id: 1415580:HNMT
uniprot id: A0A6P7YCJ5
names: Subunit
messages: Monomer.

1415580:PAQR6
gene id: 1415580:PAQR6
uniprot id: A0A6P7WP04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

1415580:FSCN2
gene id: 1415580:FSCN2
uniprot id: A0A6P7YHR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

1415580:LOC115482014
gene id: 1415580:LOC115482014
uniprot id: A0A6P7ZVU8
names: Similarity
messages: Belongs to the peptidase A1 family.

1415580:HAO1
gene id: 1415580:HAO1
uniprot id: A0A6P7XP75
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1415580:PLPPR1
gene id: 1415580:PLPPR1
uniprot id: A0A6P7X3K5
uniprot id: A0A6P7XCB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Cell membrane
messages: May play a role in neurite outgrowth and neurogenesis.
messages: Membrane
messages: neuron projection

1415580:COQ6
gene id: 1415580:COQ6
uniprot id: A0A6P7Z3Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiH/COQ6 family.
messages: Cell projection
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ7.
messages: FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
messages: Golgi apparatus
messages: Mitochondrion inner membrane

1415580:ITGA4
gene id: 1415580:ITGA4
uniprot id: A0A6P7YLU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

1415580:LOC115477769
gene id: 1415580:LOC115477769
uniprot id: A0A6P7Z5C3
names: Similarity
messages: Belongs to the ric-3 family.

1415580:NR2C1
gene id: 1415580:NR2C1
uniprot id: A0A6P7YSA5
uniprot id: A0A6P7Z3M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

1415580:KHDRBS2
gene id: 1415580:KHDRBS2
uniprot id: A0A6P7XP08
uniprot id: A0A6P7XVZ1
names: Similarity
messages: Belongs to the KHDRBS family.

1415580:TLCD4
gene id: 1415580:TLCD4
uniprot id: A0A6P7YH70
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115457847
gene id: 1415580:LOC115457847
uniprot id: A0A6P7WZK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:C8B
gene id: 1415580:C8B
uniprot id: A0A6P7Y4F8
uniprot id: A0A6P7YH90
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

1415580:ARGLU1
gene id: 1415580:ARGLU1
uniprot id: A0A6P7XW43
names: Similarity
messages: Belongs to the UPF0430 family.

1415580:LOC115466087
gene id: 1415580:LOC115466087
uniprot id: A0A6P7XIC7
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115469558
gene id: 1415580:LOC115469558
uniprot id: A0A6P7XZ84
uniprot id: A0A6P7Y615
names: Subcellular Location Annotation
messages: Membrane

1415580:QPCTL
gene id: 1415580:QPCTL
uniprot id: A0A6P7ZDU2
names: Similarity
messages: Belongs to the glutaminyl-peptide cyclotransferase family.

1415580:LOC115479292
gene id: 1415580:LOC115479292
uniprot id: A0A6P7Z0X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.
messages: Cytoplasm

1415580:GRM7
gene id: 1415580:GRM7
uniprot id: A0A6P7YDV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

1415580:CENPI
gene id: 1415580:CENPI
uniprot id: A0A6P7YLI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-I/CTF3 family.
messages: Nucleus
messages: centromere

1415580:FAM167A
gene id: 1415580:FAM167A
uniprot id: A0A6P7X780
names: Similarity
messages: Belongs to the FAM167 (SEC) family.

1415580:TEAD3
gene id: 1415580:TEAD3
uniprot id: A0A6P7ZBQ9
uniprot id: A0A6P7ZP58
uniprot id: A0A6P7ZUQ1
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.

1415580:LOC115481994
gene id: 1415580:LOC115481994
uniprot id: A0A6P7ZI68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:TCF7
gene id: 1415580:TCF7
uniprot id: A0A6P7YJQ4
uniprot id: A0A6P7YJQ9
uniprot id: A0A6P7YRV7
uniprot id: A0A6P7YRW2
uniprot id: A0A6P7YSP8
uniprot id: A0A6P7YWF7
uniprot id: A0A6P7YWG2
uniprot id: A0A6P7YWN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

1415580:NELL2
gene id: 1415580:NELL2
uniprot id: A0A6P7ZAV8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:TMEM63B
gene id: 1415580:TMEM63B
uniprot id: A0A6P7XGJ9
uniprot id: A0A6P7XLR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

1415580:EPN1
gene id: 1415580:EPN1
uniprot id: A0A6P7XDE2
uniprot id: A0A6P7XK17
uniprot id: A0A6P7XLZ0
uniprot id: A0A6P7XSB3
names: Similarity
messages: Belongs to the epsin family.

1415580:LOC115480319
gene id: 1415580:LOC115480319
uniprot id: A0A6P7ZE78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Nucleus

1415580:CPA6
gene id: 1415580:CPA6
uniprot id: A0A6P7X0K8
names: Similarity
messages: Belongs to the peptidase M14 family.

1415580:SIRT5
gene id: 1415580:SIRT5
uniprot id: A0A6P7YUS5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: In contrast to class I sirtuins, class III sirtuins have only weak deacetylase activity. Difference in substrate specificity is probably due to a larger hydrophobic pocket with 2 residues (Tyr-102 and Arg-105) that bind to malonylated and succinylated substrates and define the specificity.
messages: Mitochondrion
messages: NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.
messages: Nucleus
messages: cytosol

1415580:PRRT1B
gene id: 1415580:PRRT1B
uniprot id: A0A6P7YF33
names: Similarity
messages: Belongs to the CD225/Dispanin family.

1415580:ENPP1
gene id: 1415580:ENPP1
uniprot id: A0A6P7XGV2
names: Subcellular Location Annotation
messages: Secreted

1415580:LOC115458230
gene id: 1415580:LOC115458230
uniprot id: A0A6P7X089
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115463405
gene id: 1415580:LOC115463405
uniprot id: A0A6P7XGE4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the annexin family.
messages: Cell membrane
messages: Cytoplasm
messages: Lateral cell membrane
messages: Membrane
messages: Nucleus
messages: The full-length protein can bind eight Ca(2+) ions via the annexin repeats. Calcium binding causes a major conformation change that modifies dimer contacts and leads to surface exposure of the N-terminal phosphorylation sites; in the absence of Ca(2+), these sites are buried in the interior of the protein core. The N-terminal region becomes disordered in response to calcium-binding.
messages: cilium

1415580:SCNN1B
gene id: 1415580:SCNN1B
uniprot id: A0A6P7YN75
names: Function
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Membrane
messages: Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus.

1415580:LOC115472442
gene id: 1415580:LOC115472442
uniprot id: A0A6P7YCD4
names: Similarity
messages: Belongs to the CLCR family.

1415580:METRNL
gene id: 1415580:METRNL
uniprot id: A0A6P7YLK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the meteorin family.
messages: Secreted

1415580:LOC115464972
gene id: 1415580:LOC115464972
uniprot id: A0A6P7X6K0
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

1415580:HTT
gene id: 1415580:HTT
uniprot id: A0A6P7X3G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the huntingtin family.
messages: Cytoplasm
messages: May play a role in microtubule-mediated transport or vesicle function.
messages: Nucleus

1415580:LOC115456734
gene id: 1415580:LOC115456734
uniprot id: A0A6P7WUE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylin family.
messages: Secreted

1415580:LOC115457071
gene id: 1415580:LOC115457071
uniprot id: A0A6P7WVT1
names: Subcellular Location Annotation
messages: Membrane

1415580:DUSP26
gene id: 1415580:DUSP26
uniprot id: A0A6P7XXZ5
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

1415580:RBP2
gene id: 1415580:RBP2
uniprot id: A0A6P7YYX1
uniprot id: A0A6P7Z6S9
uniprot id: A0A6P7ZA64
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

1415580:MCL1
gene id: 1415580:MCL1
uniprot id: A0A6P7WPY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane

1415580:LOC115477092
gene id: 1415580:LOC115477092
uniprot id: A0A6P7Z1B6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Secreted

1415580:SERP2
gene id: 1415580:SERP2
uniprot id: A0A6P7XQ96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.
messages: Membrane

1415580:POLL
gene id: 1415580:POLL
uniprot id: A0A6P7Y6J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
messages: Nucleus

1415580:TOPAZ1
gene id: 1415580:TOPAZ1
uniprot id: A0A6P7YU08
names: Function
names: Subcellular Location Annotation
messages: Important for normal spermatogenesis and male fertility. Specifically required for progression to the post-meiotic stages of spermatocyte development. Seems to be necessary for normal expression levels of a number of testis-expressed gene transcripts, although its role in this process is unclear.
messages: cytosol

1415580:MYH15
gene id: 1415580:MYH15
uniprot id: A0A6P7Y4Q1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

1415580:LRP1B
gene id: 1415580:LRP1B
uniprot id: A0A6P7YTY8
names: Caution
names: Similarity
messages: Belongs to the LDLR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:SSX2IP
gene id: 1415580:SSX2IP
uniprot id: A0A6P7Y2B4
uniprot id: A0A6P7Y9E8
uniprot id: A0A6P7Y9M3
uniprot id: A0A6P7YEX4
uniprot id: A0A6P7YFK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIP family.
messages: adherens junction
messages: centriolar satellite

1415580:TRPM1
gene id: 1415580:TRPM1
uniprot id: A0A6P7WVG9
names: Subcellular Location Annotation
messages: Membrane

1415580:PPIL4
gene id: 1415580:PPIL4
uniprot id: A0A6P7XEE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1415580:PPM1K
gene id: 1415580:PPM1K
uniprot id: A0A6P7WTN2
names: Similarity
messages: Belongs to the PP2C family.

1415580:HTRA3
gene id: 1415580:HTRA3
uniprot id: A0A6P7X7M9
names: Similarity
messages: Belongs to the peptidase S1C family.

1415580:PDC
gene id: 1415580:PDC
uniprot id: A0A6P7YCF8
names: Similarity
messages: Belongs to the phosducin family.

1415580:INPPL1
gene id: 1415580:INPPL1
uniprot id: A0A6P7XTL0
uniprot id: A0A6P7XZB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.
messages: Membrane
messages: Nucleus speckle
messages: filopodium
messages: lamellipodium

1415580:ITGB5
gene id: 1415580:ITGB5
uniprot id: A0A6P7YJC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

1415580:LOC115458154
gene id: 1415580:LOC115458154
uniprot id: A0A6P7WRR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115478740
gene id: 1415580:LOC115478740
uniprot id: A0A6P7YYF7
uniprot id: A0A6P7Z431
uniprot id: A0A6P7Z910
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase maturation factor family.
messages: Endoplasmic reticulum membrane
messages: Involved in the maturation of specific proteins in the endoplasmic reticulum.
messages: Membrane

1415580:MTMR9
gene id: 1415580:MTMR9
uniprot id: A0A6P7XV79
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

1415580:ND2
gene id: 1415580:ND2
uniprot id: W5RH64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 2 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

1415580:LOC115481826
gene id: 1415580:LOC115481826
uniprot id: A0A6P7ZCL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

1415580:NRXN3
gene id: 1415580:NRXN3
uniprot id: A0A6P7Z2A2
names: Caution
names: Similarity
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:NDUFA8
gene id: 1415580:NDUFA8
uniprot id: A0A6P7YE95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA8 subunit family.
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

1415580:SYNPR
gene id: 1415580:SYNPR
uniprot id: A0A6P7YHK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

1415580:TMEM30A
gene id: 1415580:TMEM30A
uniprot id: A0A6P7XQW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC50/LEM3 family.
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane
messages: secretory vesicle membrane

1415580:LOC115457427
gene id: 1415580:LOC115457427
uniprot id: A0A6P7WNR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:TDO2
gene id: 1415580:TDO2
uniprot id: A0A6P7X287
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer. Dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:BRD1
gene id: 1415580:BRD1
uniprot id: A0A6P7Z850
names: Subcellular Location Annotation
messages: Nucleus

1415580:CCM2L
gene id: 1415580:CCM2L
uniprot id: A0A6P7YXE0
names: Similarity
messages: Belongs to the CCM2 family.

1415580:COPS7A
gene id: 1415580:COPS7A
uniprot id: A0A6P7WLQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
messages: Cytoplasm
messages: Nucleus

1415580:ZEB2
gene id: 1415580:ZEB2
uniprot id: A0A6P7YNX7
names: Similarity
messages: Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.

1415580:LOC115468080
gene id: 1415580:LOC115468080
uniprot id: A0A6P7XSG6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-1 family.
messages: Lysosome
messages: Monomer.
messages: cytosol
messages: extracellular exosome

1415580:LOC115464418
gene id: 1415580:LOC115464418
uniprot id: A0A6P7XJ32
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:SLC26A8
gene id: 1415580:SLC26A8
uniprot id: A0A6P7ZVC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1415580:TTC39C
gene id: 1415580:TTC39C
uniprot id: A0A6P7YY60
uniprot id: A0A6P7Z136
names: Similarity
messages: Belongs to the TTC39 family.

1415580:POLR2F
gene id: 1415580:POLR2F
uniprot id: A0A6P7Y993
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Component of the RNA polymerase I (Pol I), RNA polymerase II (Pol II) and RNA polymerase III (Pol III) complexes consisting of at least 13, 12 and 17 subunits, respectively.
messages: Nucleus

1415580:LOC115472742
gene id: 1415580:LOC115472742
uniprot id: A0A6P7YDH0
names: Similarity
messages: Belongs to the Niban family.

1415580:TAF8
gene id: 1415580:TAF8
uniprot id: A0A6P7ZUN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF8 family.
messages: Nucleus

1415580:ITGA1
gene id: 1415580:ITGA1
uniprot id: A0A6P7X6Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

1415580:LOC115468166
gene id: 1415580:LOC115468166
uniprot id: A0A6P7XXX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115457039
gene id: 1415580:LOC115457039
uniprot id: A0A6P7WMM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115457148
gene id: 1415580:LOC115457148
uniprot id: A0A6P7WN02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:PHC3
gene id: 1415580:PHC3
uniprot id: A0A6P7ZB59
names: Subcellular Location Annotation
messages: Nucleus

1415580:TMTC3
gene id: 1415580:TMTC3
uniprot id: A0A6P7YXF4
uniprot id: A0A6P7Z1F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

1415580:PGR
gene id: 1415580:PGR
uniprot id: A0A6P7XL04
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Cytoplasm
messages: Nucleus
messages: Steroid hormone receptor involved in the regulation of eukaryotic gene expression which affects cellular proliferation and differentiation in target tissues.

1415580:LOC115479093
gene id: 1415580:LOC115479093
uniprot id: A0A6P7ZBD3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:MAN2B1
gene id: 1415580:MAN2B1
uniprot id: A0A6P7XQV5
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

1415580:CPE
gene id: 1415580:CPE
uniprot id: A0A6P7XD42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Membrane
messages: secretory vesicle membrane

1415580:NDUFAF1
gene id: 1415580:NDUFAF1
uniprot id: A0A6P7YZK4
names: Function
names: Similarity
messages: As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
messages: Belongs to the CIA30 family.

1415580:IRF6
gene id: 1415580:IRF6
uniprot id: A0A6P7WTI3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

1415580:LOC115476741
gene id: 1415580:LOC115476741
uniprot id: A0A6P7Z0Z6
names: Subcellular Location Annotation
messages: Nucleus

1415580:SLC25A4
gene id: 1415580:SLC25A4
uniprot id: A0A6P7X4H9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

1415580:UTP11
gene id: 1415580:UTP11
uniprot id: A0A6P7ZC85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP11 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

1415580:TINAG
gene id: 1415580:TINAG
uniprot id: A0A6P7XNZ0
uniprot id: A0A6P7XVX2
names: Similarity
messages: Belongs to the peptidase C1 family.

1415580:NUP35
gene id: 1415580:NUP35
uniprot id: A0A6P7YET2
uniprot id: A0A6P7YMF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nup35 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: nuclear pore complex

1415580:PDCL
gene id: 1415580:PDCL
uniprot id: A0A6P7Y5L0
uniprot id: A0A6P7YIT2
names: Similarity
messages: Belongs to the phosducin family.

1415580:NUP93
gene id: 1415580:NUP93
uniprot id: A0A6P7XVW3
uniprot id: A0A6P7Y368
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin interacting component (NIC) family.
messages: Nucleus membrane
messages: Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance.
messages: nuclear pore complex

1415580:LOC115462456
gene id: 1415580:LOC115462456
uniprot id: A0A6P7X4T4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ferritin family.
messages: Oligomer of 24 subunits. The functional molecule is roughly spherical and contains a central cavity into which the polymeric mineral iron core is deposited.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

1415580:HYDIN
gene id: 1415580:HYDIN
uniprot id: A0A6P7YDH2
names: Similarity
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.

1415580:TPST1
gene id: 1415580:TPST1
uniprot id: A0A6P7WEC7
uniprot id: A0A6P7WKG4
uniprot id: A0A6P7WMF9
uniprot id: A0A6P7WUD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein sulfotransferase family.
messages: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
messages: Golgi apparatus membrane

1415580:LOC115460517
gene id: 1415580:LOC115460517
uniprot id: A0A6P7X6D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115465004
gene id: 1415580:LOC115465004
uniprot id: A0A6P7XKS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LUC7L
gene id: 1415580:LUC7L
uniprot id: A0A6P7YQM4
uniprot id: A0A6P7YVG0
names: Similarity
messages: Belongs to the Luc7 family.

1415580:CAPRIN1
gene id: 1415580:CAPRIN1
uniprot id: A0A6P7XVS8
uniprot id: A0A6P7Y0Q1
uniprot id: A0A6P7Y1B8
names: Similarity
messages: Belongs to the caprin family.

1415580:LOC115473286
gene id: 1415580:LOC115473286
uniprot id: A0A6P7YLM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

1415580:RHCG
gene id: 1415580:RHCG
uniprot id: A0A6P7WZ94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

1415580:FBXO46
gene id: 1415580:FBXO46
uniprot id: A0A6P7ZEG8
names: Function
messages: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

1415580:PSMD13
gene id: 1415580:PSMD13
uniprot id: A0A6P7XY46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S11 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP). The regulatory particle is made of a lid composed of 9 subunits including PSMD13, a base containing 6 ATPases and few additional components.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

1415580:SLC35D2
gene id: 1415580:SLC35D2
uniprot id: A0A6P7X1R8
uniprot id: A0A6P7X861
names: Subcellular Location Annotation
messages: Membrane

1415580:NDUFA1
gene id: 1415580:NDUFA1
uniprot id: A0A6P7YFF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA1 subunit family.
messages: Mitochondrion inner membrane

1415580:LOC115469979
gene id: 1415580:LOC115469979
uniprot id: A0A6P7XT97
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

1415580:NME7
gene id: 1415580:NME7
uniprot id: A0A6P7X523
uniprot id: A0A6P7Y9D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: cilium axoneme

1415580:LOC115479771
gene id: 1415580:LOC115479771
uniprot id: A0A6P7ZE06
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1415580:LOC115457947
gene id: 1415580:LOC115457947
uniprot id: A0A6P7WSZ6
names: Subcellular Location Annotation
messages: Membrane

1415580:PLA2G12A
gene id: 1415580:PLA2G12A
uniprot id: A0A6P7WZV3
names: Subcellular Location Annotation
messages: Secreted

1415580:LOC115468727
gene id: 1415580:LOC115468727
uniprot id: A0A6P7XVJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

1415580:OTX1
gene id: 1415580:OTX1
uniprot id: A0A6P7XIM2
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115461304
gene id: 1415580:LOC115461304
uniprot id: A0A6P7X9V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:ACAA1
gene id: 1415580:ACAA1
uniprot id: A0A6P7XKU2
uniprot id: A0A6P7XTM6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1415580:CEBPB
gene id: 1415580:CEBPB
uniprot id: A0A6P7YVZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. C/EBP subfamily.
messages: Nucleus

1415580:ENKD1
gene id: 1415580:ENKD1
uniprot id: A0A6P7Y8V0
names: Subcellular Location Annotation
messages: cilium axoneme

1415580:ABRAXAS1
gene id: 1415580:ABRAXAS1
uniprot id: A0A6P7WZ62
uniprot id: A0A6P7X752
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM175 family. Abraxas subfamily.
messages: Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.
messages: Nucleus

1415580:SLC35C1
gene id: 1415580:SLC35C1
uniprot id: A0A6P7XUN2
uniprot id: A0A6P7Y0W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPT transporter family. SLC35C subfamily.
messages: Membrane

1415580:PDCD10
gene id: 1415580:PDCD10
uniprot id: A0A6P7ZAC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDCD10 family.
messages: Cell membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

1415580:SOX11
gene id: 1415580:SOX11
uniprot id: A0A6P7XM79
names: Subcellular Location Annotation
messages: Nucleus

1415580:TMEM63C
gene id: 1415580:TMEM63C
uniprot id: A0A6P7YU05
uniprot id: A0A6P7Z0C8
uniprot id: A0A6P7Z1R6
uniprot id: A0A6P7Z595
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

1415580:SLC7A1
gene id: 1415580:SLC7A1
uniprot id: A0A6P7Y080
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

1415580:SLC44A1
gene id: 1415580:SLC44A1
uniprot id: A0A6P7XA53
uniprot id: A0A6P7XCD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

1415580:KCND2
gene id: 1415580:KCND2
uniprot id: A0A6P7Z3Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. D (Shal) (TC 1.A.1.2) subfamily. Kv4.2/KCND2 sub-subfamily.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane
messages: dendrite
messages: dendritic spine

1415580:LOC115481000
gene id: 1415580:LOC115481000
uniprot id: A0A6P7ZPM8
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

1415580:POLD1
gene id: 1415580:POLD1
uniprot id: A0A6P7XKV6
uniprot id: A0A6P7XMQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

1415580:LOC115481939
gene id: 1415580:LOC115481939
uniprot id: A0A6P7ZUW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

1415580:S1PR5
gene id: 1415580:S1PR5
uniprot id: A0A6P7XBG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

1415580:FDFT1
gene id: 1415580:FDFT1
uniprot id: A0A6P7XN77
uniprot id: A0A6P7XV83
uniprot id: A0A6P7XVT7
names: Function
names: Similarity
messages: Belongs to the phytoene/squalene synthase family.
messages: Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.

1415580:LOC115458218
gene id: 1415580:LOC115458218
uniprot id: A0A6P7X1B4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LOC115464340
gene id: 1415580:LOC115464340
uniprot id: A0A6P7XDI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane

1415580:LOC115457093
gene id: 1415580:LOC115457093
uniprot id: A0A6P7WGK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:SELENOI
gene id: 1415580:SELENOI
uniprot id: A0A6P7XG52
uniprot id: A0A6P7XPN7
uniprot id: A0A6P7XVI4
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1415580:LHX3
gene id: 1415580:LHX3
uniprot id: A0A6P7Y5T5
names: Subcellular Location Annotation
messages: Nucleus

1415580:FAM216A
gene id: 1415580:FAM216A
uniprot id: A0A6P7ZEV5
uniprot id: A0A6P7ZI35
names: Similarity
messages: Belongs to the FAM216 family.

1415580:IRAK4
gene id: 1415580:IRAK4
uniprot id: A0A6P7Z3C7
uniprot id: A0A6P7Z5G1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with MYD88 and IRAK2 to form a ternary complex called the Myddosome.
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
messages: Cytoplasm
messages: Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens.

1415580:LOC115482020
gene id: 1415580:LOC115482020
uniprot id: A0A6P7ZDI0
uniprot id: A0A6P7ZID4
uniprot id: A0A6P7ZTB0
uniprot id: A0A6P7ZV34
uniprot id: A0A6P7ZVV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

1415580:LOC115472033
gene id: 1415580:LOC115472033
uniprot id: A0A6P7YA56
uniprot id: A0A6P7YFR0
names: Similarity
messages: Belongs to the PPP4R2 family.

1415580:FZD10
gene id: 1415580:FZD10
uniprot id: A0A6P7ZH97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Membrane

1415580:LOC115465897
gene id: 1415580:LOC115465897
uniprot id: A0A6P7XHB5
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1415580:LOC115473982
gene id: 1415580:LOC115473982
uniprot id: A0A6P7YPP7
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

1415580:IL10
gene id: 1415580:IL10
uniprot id: A0A6P7ZDP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

1415580:TMEM45A
gene id: 1415580:TMEM45A
uniprot id: A0A6P7Y4E0
uniprot id: A0A6P7YA24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

1415580:SMARCD1
gene id: 1415580:SMARCD1
uniprot id: A0A6P7XEW7
uniprot id: A0A6P7XUF3
names: Similarity
messages: Belongs to the SMARCD family.

1415580:IQSEC2
gene id: 1415580:IQSEC2
uniprot id: A0A6P7XHY6
names: Similarity
messages: Belongs to the BRAG family.

1415580:ITPKB
gene id: 1415580:ITPKB
uniprot id: A0A6P7X7Q5
uniprot id: A0A6P7XGI9
uniprot id: A0A6P7XMJ2
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

1415580:LOC115457445
gene id: 1415580:LOC115457445
uniprot id: A0A6P7WWU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

1415580:ISM1
gene id: 1415580:ISM1
uniprot id: A0A6P7XNI4
uniprot id: A0A6P7XPA0
names: Similarity
messages: Belongs to the isthmin family.

1415580:U2AF2
gene id: 1415580:U2AF2
uniprot id: A0A6P7XDG2
uniprot id: A0A6P7XM10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Necessary for the splicing of pre-mRNA.
messages: Nucleus

1415580:SMARCAD1
gene id: 1415580:SMARCAD1
uniprot id: A0A6P7WZJ9
uniprot id: A0A6P7X261
uniprot id: A0A6P7X7K4
names: Subcellular Location Annotation
messages: Chromosome

1415580:ADCY4
gene id: 1415580:ADCY4
uniprot id: A0A6P7X0Y0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

1415580:EPOR
gene id: 1415580:EPOR
uniprot id: A0A6P7XQ92
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115482165
gene id: 1415580:LOC115482165
uniprot id: A0A6P7ZE45
uniprot id: A0A6P7ZUM1
uniprot id: A0A6P7ZVE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115457873
gene id: 1415580:LOC115457873
uniprot id: A0A6P7WQJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115479719
gene id: 1415580:LOC115479719
uniprot id: A0A6P7ZEA5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1415580:RIOX2
gene id: 1415580:RIOX2
uniprot id: A0A6P7XXG0
uniprot id: A0A6P7Y514
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROX family.
messages: Belongs to the ROX family. MINA53 subfamily.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.
messages: nucleolus

1415580:ADAMTS19
gene id: 1415580:ADAMTS19
uniprot id: A0A6P7XC73
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

1415580:HOXA10
gene id: 1415580:HOXA10
uniprot id: A0A6P7XZJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

1415580:RGS9BP
gene id: 1415580:RGS9BP
uniprot id: A0A6P7XSL7
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

1415580:LOC115464271
gene id: 1415580:LOC115464271
uniprot id: A0A6P7XJP7
names: Subcellular Location Annotation
messages: Membrane

1415580:EXOSC2
gene id: 1415580:EXOSC2
uniprot id: A0A6P7YKZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP4 family.
messages: Cytoplasm

1415580:LHFPL6
gene id: 1415580:LHFPL6
uniprot id: A0A6P7XZW5
names: Subcellular Location Annotation
messages: Membrane

1415580:LYVE1
gene id: 1415580:LYVE1
uniprot id: A0A6P7Y1D0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:PDP2
gene id: 1415580:PDP2
uniprot id: A0A6P7Y5U8
names: Similarity
messages: Belongs to the PP2C family.

1415580:LOC115464803
gene id: 1415580:LOC115464803
uniprot id: A0A6P7XEV8
names: Similarity
messages: Belongs to the GDNFR family.

1415580:LRRFIP1
gene id: 1415580:LRRFIP1
uniprot id: A0A6P7YH71
uniprot id: A0A6P7YH76
uniprot id: A0A6P7YH80
uniprot id: A0A6P7YP31
uniprot id: A0A6P7YP38
uniprot id: A0A6P7YPX1
uniprot id: A0A6P7YPX7
uniprot id: A0A6P7YPY3
uniprot id: A0A6P7YU20
uniprot id: A0A6P7YU24
uniprot id: A0A6P7YU39
uniprot id: A0A6P7YU43
names: Similarity
messages: Belongs to the LRRFIP family.

1415580:LOC115479862
gene id: 1415580:LOC115479862
uniprot id: A0A6P7Z3V5
names: Subcellular Location Annotation
messages: Nucleus

1415580:DEDD2
gene id: 1415580:DEDD2
uniprot id: A0A6P7YQC4
names: Subcellular Location Annotation
messages: nucleolus

1415580:LOC115456580
gene id: 1415580:LOC115456580
uniprot id: A0A6P7WEN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

1415580:PGM5
gene id: 1415580:PGM5
uniprot id: A0A6P7X8N8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1415580:LOC115471161
gene id: 1415580:LOC115471161
uniprot id: A0A6P7Y6X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:FAP
gene id: 1415580:FAP
uniprot id: A0A6P7YKX0
uniprot id: A0A6P7YQB3
names: Subcellular Location Annotation
messages: Cell membrane
messages: invadopodium membrane
messages: lamellipodium membrane

1415580:LOC115465747
gene id: 1415580:LOC115465747
uniprot id: A0A6P7XIP9
names: Similarity
messages: Belongs to the PRORSD1 family.

1415580:LOC115460707
gene id: 1415580:LOC115460707
uniprot id: A0A6P7X6W6
names: Similarity
messages: Belongs to the MINAR family.

1415580:CENPX
gene id: 1415580:CENPX
uniprot id: A0A6P7Y7T1
uniprot id: A0A6P7YE01
names: Similarity
messages: Belongs to the CENP-X/MHF2 family.

1415580:ST6GAL2
gene id: 1415580:ST6GAL2
uniprot id: A0A6P7XQP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

1415580:LOC115469635
gene id: 1415580:LOC115469635
uniprot id: A0A6P7Y6B4
names: Similarity
messages: Belongs to the helicase family.

1415580:MANF
gene id: 1415580:MANF
uniprot id: A0A6P7YJC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARMET family.
messages: Secreted

1415580:CRABP1
gene id: 1415580:CRABP1
uniprot id: A0A6P7WSW0
names: Function
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytosolic CRABPs may regulate the access of retinoic acid to the nuclear retinoic acid receptors.

1415580:HYOU1
gene id: 1415580:HYOU1
uniprot id: A0A6P7ZUP2
uniprot id: A0A6P7ZVE8
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1415580:LOC115475034
gene id: 1415580:LOC115475034
uniprot id: A0A6P7YNN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115480996
gene id: 1415580:LOC115480996
uniprot id: A0A6P7ZDK3
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115474517
gene id: 1415580:LOC115474517
uniprot id: A0A6P7YEK4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Cytoplasm
messages: Homodimer.

1415580:LOC115464445
gene id: 1415580:LOC115464445
uniprot id: A0A6P7XJ58
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LOC115458071
gene id: 1415580:LOC115458071
uniprot id: A0A6P7WRE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:RPIA
gene id: 1415580:RPIA
uniprot id: A0A6P7WUR5
uniprot id: A0A6P7X0J6
names: Similarity
messages: Belongs to the ribose 5-phosphate isomerase family.

1415580:LOC115458215
gene id: 1415580:LOC115458215
uniprot id: A0A6P7X075
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115479333
gene id: 1415580:LOC115479333
uniprot id: A0A6P7Z8Y7
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115473729
gene id: 1415580:LOC115473729
uniprot id: A0A6P7YN73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Secreted

1415580:WARS1
gene id: 1415580:WARS1
uniprot id: A0A6P7Z031
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1415580:NACC2
gene id: 1415580:NACC2
uniprot id: A0A6P7Y8J0
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115465304
gene id: 1415580:LOC115465304
uniprot id: A0A6P7X7P4
uniprot id: A0A6P7XEC5
uniprot id: A0A6P7XEF1
uniprot id: A0A6P7XLM7
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

1415580:TEC
gene id: 1415580:TEC
uniprot id: A0A6P7X444
uniprot id: A0A6P7X9G6
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

1415580:GFM2
gene id: 1415580:GFM2
uniprot id: A0A6P7XFX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
messages: Mitochondrion

1415580:RAB3IP
gene id: 1415580:RAB3IP
uniprot id: A0A6P7YTN5
uniprot id: A0A6P7Z1D2
names: Similarity
messages: Belongs to the SEC2 family.

1415580:LOC115469568
gene id: 1415580:LOC115469568
uniprot id: A0A6P7Y638
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

1415580:PDE6D
gene id: 1415580:PDE6D
uniprot id: A0A6P7Z4T5
uniprot id: A0A6P7ZAC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PDE6D/unc-119 family.
messages: Cytoplasmic vesicle membrane
messages: Interacts with the prenylated catalytic subunits of PDE6, an oligomer composed of two catalytic chains and two inhibitory chains; has no effect on enzyme activity but promotes the release of the prenylated enzyme from cell membrane.
messages: Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate.
messages: cilium basal body
messages: cytosol

1415580:LIN7B
gene id: 1415580:LIN7B
uniprot id: A0A6P7XTN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-7 family.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.

1415580:PACC1
gene id: 1415580:PACC1
uniprot id: A0A6P7XB21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proton-activated chloride channel family.
messages: Cell membrane
messages: Membrane

1415580:ACTR3
gene id: 1415580:ACTR3
uniprot id: A0A6P7Y2U4
names: Similarity
messages: Belongs to the actin family. ARP3 subfamily.

1415580:SCTR
gene id: 1415580:SCTR
uniprot id: A0A6P7YNY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

1415580:NSUN6
gene id: 1415580:NSUN6
uniprot id: A0A6P7X6K5
uniprot id: A0A6P7X6L1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1415580:CRPPA
gene id: 1415580:CRPPA
uniprot id: A0A6P7XW54
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Homodimer.
messages: cytosol

1415580:ST8SIA3
gene id: 1415580:ST8SIA3
uniprot id: A0A6P7XCP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

1415580:RTRAF
gene id: 1415580:RTRAF
uniprot id: A0A6P7Z541
names: Similarity
messages: Belongs to the RTRAF family.

1415580:LOC115468164
gene id: 1415580:LOC115468164
uniprot id: A0A6P7XST1
names: Subcellular Location Annotation
messages: Membrane

1415580:THBS2
gene id: 1415580:THBS2
uniprot id: A0A6P7XF44
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:CCR10
gene id: 1415580:CCR10
uniprot id: A0A6P7ZDA5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:ADCY3
gene id: 1415580:ADCY3
uniprot id: A0A6P7XG94
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

1415580:LOC115481170
gene id: 1415580:LOC115481170
uniprot id: A0A6P7ZR11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the argonaute family.
messages: P-body

1415580:LOC115480935
gene id: 1415580:LOC115480935
uniprot id: A0A6P7ZPA1
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

1415580:LOC115481231
gene id: 1415580:LOC115481231
uniprot id: A0A6P7WW72
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1415580:GPATCH11
gene id: 1415580:GPATCH11
uniprot id: A0A6P7XIJ0
names: Similarity
messages: Belongs to the GPATCH11 family.

1415580:ZFHX4
gene id: 1415580:ZFHX4
uniprot id: A0A6P7Z729
names: Subcellular Location Annotation
messages: Nucleus

1415580:GLRB
gene id: 1415580:GLRB
uniprot id: A0A6P7X5G4
uniprot id: A0A6P7XD53
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:TMEM201
gene id: 1415580:TMEM201
uniprot id: A0A6P7WTN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM201 family.
messages: Membrane
messages: Nucleus inner membrane

1415580:LLGL2
gene id: 1415580:LLGL2
uniprot id: A0A6P7YGH3
uniprot id: A0A6P7YGQ1
names: Similarity
messages: Belongs to the WD repeat L(2)GL family.

1415580:IAPP
gene id: 1415580:IAPP
uniprot id: A0A6P7YQK3
names: Similarity
messages: Belongs to the calcitonin family.

1415580:GMFG
gene id: 1415580:GMFG
uniprot id: A0A6P7ZJ02
names: Similarity
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.

1415580:ATP11C
gene id: 1415580:ATP11C
uniprot id: A0A6P7YFL3
uniprot id: A0A6P7YMH7
uniprot id: A0A6P7YN88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

1415580:UBE2H
gene id: 1415580:UBE2H
uniprot id: A0A6P7Z5Y4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

1415580:NAB2
gene id: 1415580:NAB2
uniprot id: A0A6P7XH43
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAB family.
messages: Homomultimers may associate with EGR1 bound to DNA.
messages: Nucleus

1415580:ACOX3
gene id: 1415580:ACOX3
uniprot id: A0A6P7X3H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

1415580:RNFT1
gene id: 1415580:RNFT1
uniprot id: A0A6P8A189
names: Subcellular Location Annotation
messages: Membrane

1415580:PPP2R5E
gene id: 1415580:PPP2R5E
uniprot id: A0A6P7YW55
uniprot id: A0A6P7Z257
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

1415580:SHMT2
gene id: 1415580:SHMT2
uniprot id: A0A6P7XA90
uniprot id: A0A6P7XH30
uniprot id: A0A6P7XQ44
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

1415580:HACD4
gene id: 1415580:HACD4
uniprot id: A0A6P7XC23
uniprot id: A0A6P7XC27
uniprot id: A0A6P7XHC1
uniprot id: A0A6P7XIG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:LOC115458168
gene id: 1415580:LOC115458168
uniprot id: A0A6P7WRT2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LOC115475599
gene id: 1415580:LOC115475599
uniprot id: A0A6P7YQR5
names: Similarity
messages: Belongs to the CCNDBP1 family.

1415580:TMEM129
gene id: 1415580:TMEM129
uniprot id: A0A6P7WUW9
uniprot id: A0A6P7X0R3
uniprot id: A0A6P7X3B6
uniprot id: A0A6P7X8S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM129 family.
messages: Membrane

1415580:SEC61B
gene id: 1415580:SEC61B
uniprot id: A0A6P7Y7R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC61-beta family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Necessary for protein translocation in the endoplasmic reticulum.

1415580:LOC115473106
gene id: 1415580:LOC115473106
uniprot id: A0A6P7YF12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

1415580:BMP6
gene id: 1415580:BMP6
uniprot id: A0A6P7YBE6
names: Similarity
messages: Belongs to the TGF-beta family.

1415580:SARS1
gene id: 1415580:SARS1
uniprot id: A0A6P7ZPX8
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.

1415580:LOC115477528
gene id: 1415580:LOC115477528
uniprot id: A0A6P7Z4A7
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1415580:RIN3
gene id: 1415580:RIN3
uniprot id: A0A6P7YYD5
uniprot id: A0A6P7Z2F5
names: Similarity
messages: Belongs to the RIN (Ras interaction/interference) family.

1415580:LOC115464709
gene id: 1415580:LOC115464709
uniprot id: A0A6P7XJY1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:ERMN
gene id: 1415580:ERMN
uniprot id: A0A6P7YL24
names: Function
names: Subunit
messages: Binds actin.
messages: Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. May play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS.

1415580:LOC115473325
gene id: 1415580:LOC115473325
uniprot id: A0A6P7YLQ7
names: Similarity
messages: Belongs to the glutamine synthetase family.

1415580:ACER1
gene id: 1415580:ACER1
uniprot id: A0A6P7ZD15
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:DNAJC25
gene id: 1415580:DNAJC25
uniprot id: A0A6P7X8G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNAJC25 family.
messages: Membrane

1415580:NDEL1
gene id: 1415580:NDEL1
uniprot id: A0A6P7Y916
uniprot id: A0A6P7YLI4
uniprot id: A0A6P7YLQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: spindle

1415580:NKX2-2
gene id: 1415580:NKX2-2
uniprot id: A0A6P7XJS2
names: Subcellular Location Annotation
messages: Nucleus

1415580:XKR8
gene id: 1415580:XKR8
uniprot id: A0A6P7ZA22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

1415580:CEP170B
gene id: 1415580:CEP170B
uniprot id: A0A6P7Z001
names: Similarity
messages: Belongs to the CEP170 family.

1415580:SLC41A3
gene id: 1415580:SLC41A3
uniprot id: A0A6P7YJI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:PI4KA
gene id: 1415580:PI4KA
uniprot id: A0A6P7ZCL4
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

1415580:LOC115464354
gene id: 1415580:LOC115464354
uniprot id: A0A6P7XDJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.
messages: Membrane
messages: The cofactor is mostly bound to the substrate.

1415580:UTP6
gene id: 1415580:UTP6
uniprot id: A0A6P7YGW4
names: Similarity
messages: Belongs to the UTP6 family.

1415580:PITPNM3
gene id: 1415580:PITPNM3
uniprot id: A0A6P7WF97
names: Similarity
messages: Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.

1415580:EYA2
gene id: 1415580:EYA2
uniprot id: A0A6P7YW01
uniprot id: A0A6P7YZS1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

1415580:KIT
gene id: 1415580:KIT
uniprot id: A0A6P7X472
uniprot id: A0A6P7XAV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

1415580:LOC115471938
gene id: 1415580:LOC115471938
uniprot id: A0A6P7YFZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

1415580:LOC115479202
gene id: 1415580:LOC115479202
uniprot id: A0A6P7Z8F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 32 family.
messages: Golgi apparatus membrane

1415580:CPTP
gene id: 1415580:CPTP
uniprot id: A0A6P7ZN51
names: Similarity
messages: Belongs to the GLTP family.

1415580:LOC115473387
gene id: 1415580:LOC115473387
uniprot id: A0A6P7YGM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase d subunit family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

1415580:LOC115474455
gene id: 1415580:LOC115474455
uniprot id: A0A6P7YRJ1
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1415580:LOC115457985
gene id: 1415580:LOC115457985
uniprot id: A0A6P7WZ55
uniprot id: A0A6P7X0B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:VAX1
gene id: 1415580:VAX1
uniprot id: A0A6P7Y6S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMX homeobox family.
messages: Nucleus

1415580:LOC115457425
gene id: 1415580:LOC115457425
uniprot id: A0A6P7WQR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:SKA3
gene id: 1415580:SKA3
uniprot id: A0A6P7XL80
uniprot id: A0A6P7XSY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKA3 family.
messages: kinetochore
messages: spindle

1415580:TNS3
gene id: 1415580:TNS3
uniprot id: A0A6P7YPG5
uniprot id: A0A6P7YPT2
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

1415580:CHDH
gene id: 1415580:CHDH
uniprot id: A0A6P7Y635
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1415580:LOC115473940
gene id: 1415580:LOC115473940
uniprot id: A0A6P7YJD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cell membrane

1415580:LOC115476461
gene id: 1415580:LOC115476461
uniprot id: A0A6P7YUQ3
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with ATP6V0C.
messages: Membrane

1415580:LOC115457127
gene id: 1415580:LOC115457127
uniprot id: A0A6P7WMU7
names: Subcellular Location Annotation
messages: Membrane

1415580:FRG1
gene id: 1415580:FRG1
uniprot id: A0A6P7X4F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRG1 family.
messages: Cajal body
messages: nucleolus

1415580:LOC115464555
gene id: 1415580:LOC115464555
uniprot id: A0A6P7XJG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115463431
gene id: 1415580:LOC115463431
uniprot id: A0A6P7XB85
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

1415580:TMEM9
gene id: 1415580:TMEM9
uniprot id: A0A6P7ZCF3
names: Similarity
messages: Belongs to the TMEM9 family.

1415580:PEX10
gene id: 1415580:PEX10
uniprot id: A0A6P7WFF5
names: Function
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.
messages: Somewhat implicated in the biogenesis of peroxisomes.

1415580:LCMT1
gene id: 1415580:LCMT1
uniprot id: A0A6P7YRP5
uniprot id: A0A6P7YVQ8
uniprot id: A0A6P7YVW2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. LCMT family.
messages: Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.

1415580:LOC115481948
gene id: 1415580:LOC115481948
uniprot id: A0A6P7ZSP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:DKK3
gene id: 1415580:DKK3
uniprot id: A0A6P7XNA4
uniprot id: A0A6P7XV26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

1415580:PPM1F
gene id: 1415580:PPM1F
uniprot id: A0A6P7Z972
names: Similarity
messages: Belongs to the PP2C family.

1415580:TMEM86B
gene id: 1415580:TMEM86B
uniprot id: A0A6P7XDG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

1415580:LOC115469920
gene id: 1415580:LOC115469920
uniprot id: A0A6P7Y619
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115462851
gene id: 1415580:LOC115462851
uniprot id: A0A6P7XDR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS1 family.
messages: spindle

1415580:MED22
gene id: 1415580:MED22
uniprot id: A0A6P7Y7U8
uniprot id: A0A6P7YEY3
uniprot id: A0A6P7YF89
uniprot id: A0A6P7YKR8
names: Function
names: Subcellular Location Annotation
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

1415580:LOC115468324
gene id: 1415580:LOC115468324
uniprot id: A0A6P7XK40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:SRPX2
gene id: 1415580:SRPX2
uniprot id: A0A6P7YB79
names: Caution
names: Subcellular Location Annotation
messages: Cell surface
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Synapse

1415580:LOC115477383
gene id: 1415580:LOC115477383
uniprot id: A0A6P7Z2V3
names: Similarity
messages: Belongs to the aldo/keto reductase family.

1415580:OPN3
gene id: 1415580:OPN3
uniprot id: A0A6P7X640
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

1415580:CKM
gene id: 1415580:CKM
uniprot id: A0A6P7ZDA4
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

1415580:CPNE8
gene id: 1415580:CPNE8
uniprot id: A0A6P7Z428
names: Similarity
messages: Belongs to the copine family.

1415580:IRAK1BP1
gene id: 1415580:IRAK1BP1
uniprot id: A0A6P7XG93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRAK1BP1 family.
messages: Cytoplasm
messages: Nucleus

1415580:LOC115478682
gene id: 1415580:LOC115478682
uniprot id: A0A6P7Z9E7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myo-inositol oxygenase family.
messages: Binds 2 iron ions per subunit.
messages: Cytoplasm

1415580:SETD1B
gene id: 1415580:SETD1B
uniprot id: A0A6P7Z783
uniprot id: A0A6P7ZC31
uniprot id: A0A6P7ZJA8
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus speckle

1415580:LOC115457188
gene id: 1415580:LOC115457188
uniprot id: A0A6P7WQ23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:SPDYC
gene id: 1415580:SPDYC
uniprot id: A0A6P7ZE30
uniprot id: A0A6P7ZGM4
uniprot id: A0A6P7ZHD8
names: Similarity
messages: Belongs to the Speedy/Ringo family.

1415580:NIP7
gene id: 1415580:NIP7
uniprot id: A0A6P7YCG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NIP7 family.
messages: Interacts with pre-ribosome complex.
messages: Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.
messages: nucleolus

1415580:LOC115460669
gene id: 1415580:LOC115460669
uniprot id: A0A6P7X803
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:PLCB2
gene id: 1415580:PLCB2
uniprot id: A0A6P7Z2V1
names: Function
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

1415580:LOC115471192
gene id: 1415580:LOC115471192
uniprot id: A0A6P7Y6Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

1415580:CHRD
gene id: 1415580:CHRD
uniprot id: A0A6P7Z5Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chordin family.
messages: Secreted

1415580:TNFRSF14
gene id: 1415580:TNFRSF14
uniprot id: A0A6P7WFR1
uniprot id: A0A6P7WUW1
uniprot id: A0A6P7WVW9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115466196
gene id: 1415580:LOC115466196
uniprot id: A0A6P7XC51
uniprot id: A0A6P7XIX1
uniprot id: A0A6P7XKX4
names: Similarity
messages: Belongs to the MHC class I family.

1415580:LOC115470433
gene id: 1415580:LOC115470433
uniprot id: A0A6P7Y2U4
names: Similarity
messages: Belongs to the actin family. ARP3 subfamily.

1415580:SFXN4
gene id: 1415580:SFXN4
uniprot id: A0A6P7Y6W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane

1415580:ADCK5
gene id: 1415580:ADCK5
uniprot id: A0A6P7ZFA6
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

1415580:LOC115460522
gene id: 1415580:LOC115460522
uniprot id: A0A6P7WYC4
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

1415580:MARCO
gene id: 1415580:MARCO
uniprot id: A0A6P7YNZ3
uniprot id: A0A6P7YT85
uniprot id: A0A6P7YTA4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:DPF3
gene id: 1415580:DPF3
uniprot id: A0A6P7YSD9
uniprot id: A0A6P7YYU5
uniprot id: A0A6P7Z008
uniprot id: A0A6P7Z3Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the requiem/DPF family.
messages: Nucleus

1415580:PURB
gene id: 1415580:PURB
uniprot id: A0A6P7Y436
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

1415580:LOC115475085
gene id: 1415580:LOC115475085
uniprot id: A0A6P7YTT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115461625
gene id: 1415580:LOC115461625
uniprot id: A0A6P7XBD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain.
messages: Nucleus

1415580:LOC115480671
gene id: 1415580:LOC115480671
uniprot id: A0A6P7ZG64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.
messages: Membrane
messages: Mitochondrion

1415580:LOC115474370
gene id: 1415580:LOC115474370
uniprot id: A0A6P7WVA0
names: Subcellular Location Annotation
messages: Nucleus

1415580:NRCAM
gene id: 1415580:NRCAM
uniprot id: A0A6P7YX65
uniprot id: A0A6P7Z2Y1
uniprot id: A0A6P7Z4Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
messages: Membrane

1415580:SLC41A1
gene id: 1415580:SLC41A1
uniprot id: A0A6P7ZGN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

1415580:LOC115478828
gene id: 1415580:LOC115478828
uniprot id: A0A6P7YYU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane
messages: Sodium-independent transporter of chloride and iodide.

1415580:ADAMTS18
gene id: 1415580:ADAMTS18
uniprot id: A0A6P7Y055
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:CRY2
gene id: 1415580:CRY2
uniprot id: A0A6P7XMU2
uniprot id: A0A6P7XVZ3
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.

1415580:NXPH3
gene id: 1415580:NXPH3
uniprot id: A0A6P7ZW93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

1415580:AASDHPPT
gene id: 1415580:AASDHPPT
uniprot id: A0A6P7XIC0
uniprot id: A0A6P7XRW6
uniprot id: A0A6P7XX17
uniprot id: A0A6P7XXP7
names: Similarity
messages: Belongs to the P-Pant transferase superfamily. AcpS family.

1415580:ALOX5AP
gene id: 1415580:ALOX5AP
uniprot id: A0A6P7XQ64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:JUNB
gene id: 1415580:JUNB
uniprot id: A0A6P7XK01
uniprot id: A0A6P7XQX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

1415580:LOC115458431
gene id: 1415580:LOC115458431
uniprot id: A0A6P7WLT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:CCDC25
gene id: 1415580:CCDC25
uniprot id: A0A6P7XV35
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CCDC25 family.
messages: Cell membrane
messages: Endomembrane system
messages: Interacts (via cytoplasmic region) with ILK.

1415580:DCLRE1A
gene id: 1415580:DCLRE1A
uniprot id: A0A6P7Y0A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

1415580:EPHA5
gene id: 1415580:EPHA5
uniprot id: A0A6P7XAU2
uniprot id: A0A6P7XD40
names: Subcellular Location Annotation
messages: Membrane

1415580:CD6
gene id: 1415580:CD6
uniprot id: A0A6P7WV16
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115472880
gene id: 1415580:LOC115472880
uniprot id: A0A6P7YE50
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: cytosol

1415580:NOX3
gene id: 1415580:NOX3
uniprot id: A0A6P7XLY1
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115466260
gene id: 1415580:LOC115466260
uniprot id: A0A6P7XRG8
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1415580:RPAIN
gene id: 1415580:RPAIN
uniprot id: A0A6P7WNN0
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115464426
gene id: 1415580:LOC115464426
uniprot id: A0A6P7XJ42
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:S100A16
gene id: 1415580:S100A16
uniprot id: A0A6P7WWV1
names: Similarity
messages: Belongs to the S-100 family.

1415580:LOC115457089
gene id: 1415580:LOC115457089
uniprot id: A0A6P7WPR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:ATP6
gene id: 1415580:ATP6
uniprot id: W5RHL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
messages: Mitochondrion inner membrane

1415580:PLAG1
gene id: 1415580:PLAG1
uniprot id: A0A6P7YTF7
uniprot id: A0A6P7Z418
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: Nucleus

1415580:LOC115463461
gene id: 1415580:LOC115463461
uniprot id: A0A6P7X951
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

1415580:LOC115461219
gene id: 1415580:LOC115461219
uniprot id: A0A6P7WUD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:MTERF4
gene id: 1415580:MTERF4
uniprot id: A0A6P7YZ48
names: Similarity
messages: Belongs to the mTERF family.

1415580:MANEA
gene id: 1415580:MANEA
uniprot id: A0A6P7XL33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

1415580:AMER2
gene id: 1415580:AMER2
uniprot id: A0A6P7XX27
names: Similarity
messages: Belongs to the Amer family.

1415580:FEV
gene id: 1415580:FEV
uniprot id: A0A6P7YFR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

1415580:C12H11orf88
gene id: 1415580:C12H11orf88
uniprot id: A0A6P7ZB92
names: Similarity
messages: Belongs to the HOATZ family.

1415580:TRIM67
gene id: 1415580:TRIM67
uniprot id: A0A6P7XKB6
names: Subcellular Location Annotation
messages: cytoskeleton

1415580:LOC115477393
gene id: 1415580:LOC115477393
uniprot id: A0A6P7Z003
uniprot id: A0A6P7Z3P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAIF1 family.
messages: Induces apoptosis.
messages: Nucleus

1415580:MRPL52
gene id: 1415580:MRPL52
uniprot id: A0A6P7WJS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL52 family.
messages: Mitochondrion

1415580:MATN2
gene id: 1415580:MATN2
uniprot id: A0A6P7ZC02
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115460547
gene id: 1415580:LOC115460547
uniprot id: A0A6P7WSK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:NPFFR2
gene id: 1415580:NPFFR2
uniprot id: A0A6P7WXP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

1415580:ABT1
gene id: 1415580:ABT1
uniprot id: A0A6P7X912
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF2/ABP1 family.
messages: nucleolus

1415580:MRPL41
gene id: 1415580:MRPL41
uniprot id: A0A6P7YAW1
uniprot id: A0A6P7YG48
uniprot id: A0A6P7YGQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL41 family.
messages: Mitochondrion

1415580:HSPB7
gene id: 1415580:HSPB7
uniprot id: A0A6P7ZF54
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1415580:LOC115464436
gene id: 1415580:LOC115464436
uniprot id: A0A6P7X4Z4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LOC115465525
gene id: 1415580:LOC115465525
uniprot id: A0A6P7XMP3
uniprot id: A0A6P7XNC6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1415580:EN1
gene id: 1415580:EN1
uniprot id: A0A6P7YLN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Engrailed homeobox family.
messages: Nucleus

1415580:TAT
gene id: 1415580:TAT
uniprot id: A0A6P7XYU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.

1415580:LOC115465463
gene id: 1415580:LOC115465463
uniprot id: A0A6P7X8C2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: The PAL motif is required for normal active site conformation.

1415580:NUP107
gene id: 1415580:NUP107
uniprot id: A0A6P7Z3M1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup84/Nup107 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: Part of the nuclear pore complex (NPC).
messages: nuclear pore complex

1415580:STX12
gene id: 1415580:STX12
uniprot id: A0A6P7ZA26
names: Similarity
messages: Belongs to the syntaxin family.

1415580:LOC115476895
gene id: 1415580:LOC115476895
uniprot id: A0A6P7YQ05
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.

1415580:LOC115476290
gene id: 1415580:LOC115476290
uniprot id: A0A6P7YYA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

1415580:DST
gene id: 1415580:DST
uniprot id: A0A6P7XH79
uniprot id: A0A6P7XP00
uniprot id: A0A6P7XVY0
names: Subcellular Location Annotation
messages: cytoskeleton

1415580:JPH4
gene id: 1415580:JPH4
uniprot id: A0A6P7WJX4
uniprot id: A0A6P7WT85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:LOC115468491
gene id: 1415580:LOC115468491
uniprot id: A0A6P7XL26
names: Similarity
messages: Belongs to the peptidase M10A family.

1415580:STK38
gene id: 1415580:STK38
uniprot id: A0A6P7ZVH5
names: Similarity
messages: Belongs to the protein kinase superfamily.

1415580:LOC115457789
gene id: 1415580:LOC115457789
uniprot id: A0A6P7WZA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DAD/OST2 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

1415580:NES
gene id: 1415580:NES
uniprot id: A0A6P7WRJ4
names: Similarity
messages: Belongs to the intermediate filament family.

1415580:ERBB2
gene id: 1415580:ERBB2
uniprot id: A0A6P7ZET1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

1415580:IL18R1
gene id: 1415580:IL18R1
uniprot id: A0A6P7Y2T0
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

1415580:LOC115461168
gene id: 1415580:LOC115461168
uniprot id: A0A6P7X7V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:NEUROD2
gene id: 1415580:NEUROD2
uniprot id: A0A6P7ZE14
names: Subcellular Location Annotation
messages: Nucleus

1415580:NFYA
gene id: 1415580:NFYA
uniprot id: A0A6P7ZSD3
uniprot id: A0A6P7ZUT7
uniprot id: A0A6P7ZVJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NFYA/HAP2 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
messages: Heterotrimer.
messages: Nucleus

1415580:CNNM1
gene id: 1415580:CNNM1
uniprot id: A0A6P7XZ64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Membrane

1415580:LOC115479634
gene id: 1415580:LOC115479634
uniprot id: A0A6P7Z2I3
names: Similarity
messages: Belongs to the selenoprotein M/F family.

1415580:TSPAN32
gene id: 1415580:TSPAN32
uniprot id: A0A6P7Y2K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

1415580:SH3BP5L
gene id: 1415580:SH3BP5L
uniprot id: A0A6P7XK97
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

1415580:BCO1
gene id: 1415580:BCO1
uniprot id: A0A6P7Y5X6
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

1415580:GNG12
gene id: 1415580:GNG12
uniprot id: A0A6P7YI77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

1415580:FIGNL1
gene id: 1415580:FIGNL1
uniprot id: A0A6P7WRW1
names: Similarity
messages: Belongs to the AAA ATPase family.

1415580:PCYT2
gene id: 1415580:PCYT2
uniprot id: A0A6P7Y0B1
names: Similarity
messages: Belongs to the cytidylyltransferase family.

1415580:CCDC172
gene id: 1415580:CCDC172
uniprot id: A0A6P7Y6Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC172 family.
messages: Cytoplasm

1415580:LOC115457389
gene id: 1415580:LOC115457389
uniprot id: A0A6P7WHC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:DUSP3
gene id: 1415580:DUSP3
uniprot id: A0A6P7ZV11
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

1415580:SLC25A20
gene id: 1415580:SLC25A20
uniprot id: A0A6P7YBV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1415580:LOC115469314
gene id: 1415580:LOC115469314
uniprot id: A0A6P7XXK3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:FGFR2
gene id: 1415580:FGFR2
uniprot id: A0A6P7XSR3
uniprot id: A0A6P7Y022
uniprot id: A0A6P7Y0W3
uniprot id: A0A6P7Y5S1
uniprot id: A0A6P7Y5S7
uniprot id: A0A6P7Y6U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Cell membrane
messages: Membrane

1415580:ATG9A
gene id: 1415580:ATG9A
uniprot id: A0A6P7YRL3
uniprot id: A0A6P7YRT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

1415580:UBE2K
gene id: 1415580:UBE2K
uniprot id: A0A6P7X9C2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

1415580:GLRA2
gene id: 1415580:GLRA2
uniprot id: A0A6P7XXJ0
uniprot id: A0A6P7XYA2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

1415580:LCA5
gene id: 1415580:LCA5
uniprot id: A0A6P7XW51
names: Similarity
messages: Belongs to the LCA5 family.

1415580:LOC115480597
gene id: 1415580:LOC115480597
uniprot id: A0A6P7Z7C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcriptional coactivator PC4 family.
messages: General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
messages: Nucleus

1415580:LOC115476596
gene id: 1415580:LOC115476596
uniprot id: A0A6P7YNN5
uniprot id: A0A6P7YVB5
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

1415580:LOXHD1
gene id: 1415580:LOXHD1
uniprot id: A0A6P7XEZ1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:PIH1D2
gene id: 1415580:PIH1D2
uniprot id: A0A6P7ZMX3
names: Similarity
messages: Belongs to the PIH1 family.

1415580:LOC115482183
gene id: 1415580:LOC115482183
uniprot id: A0A6P7ZW89
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

1415580:P4HB
gene id: 1415580:P4HB
uniprot id: A0A6P7YD93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

1415580:ADAM17
gene id: 1415580:ADAM17
uniprot id: A0A6P7XQC4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:ADAMTS1
gene id: 1415580:ADAMTS1
uniprot id: A0A6P7YAT1
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

1415580:BICD1
gene id: 1415580:BICD1
uniprot id: A0A6P7Z2S7
names: Similarity
messages: Belongs to the BicD family.

1415580:ATG4C
gene id: 1415580:ATG4C
uniprot id: A0A6P7YC11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

1415580:LOC115457857
gene id: 1415580:LOC115457857
uniprot id: A0A6P7WSL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115472863
gene id: 1415580:LOC115472863
uniprot id: A0A6P7YJQ3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

1415580:CXXC5
gene id: 1415580:CXXC5
uniprot id: A0A6P7YX44
names: Subcellular Location Annotation
messages: Cytoplasm

1415580:PFDN2
gene id: 1415580:PFDN2
uniprot id: A0A6P7WZK8
names: Function
names: Similarity
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

1415580:FBN1
gene id: 1415580:FBN1
uniprot id: A0A6P7X4C3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fibrillin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

1415580:LOC115466517
gene id: 1415580:LOC115466517
uniprot id: A0A6P7XDP3
uniprot id: A0A6P7XM98
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

1415580:LOC115468259
gene id: 1415580:LOC115468259
uniprot id: A0A6P7XT47
names: Subcellular Location Annotation
messages: Membrane

1415580:ALCAM
gene id: 1415580:ALCAM
uniprot id: A0A6P7Y530
names: Subcellular Location Annotation
messages: Cell membrane
messages: axon
messages: dendrite

1415580:LOC115458056
gene id: 1415580:LOC115458056
uniprot id: A0A6P7WTH0
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

1415580:CHRNB1
gene id: 1415580:CHRNB1
uniprot id: A0A6P7WQY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

1415580:SMDT1
gene id: 1415580:SMDT1
uniprot id: A0A6P7WRM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMDT1/EMRE family.
messages: Component of the uniplex complex. Interacts (via the transmembrane region) with MCU (via the first transmembrane region); the interaction is direct.
messages: Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

1415580:ELAVL1
gene id: 1415580:ELAVL1
uniprot id: A0A6P7ZA06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM elav family.
messages: Cytoplasm

1415580:LOC115475598
gene id: 1415580:LOC115475598
uniprot id: A0A6P7YIM9
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.

1415580:LOC115462559
gene id: 1415580:LOC115462559
uniprot id: A0A6P7X526
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shootin family.
messages: axon
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

1415580:LOC115465024
gene id: 1415580:LOC115465024
uniprot id: A0A6P7X6Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin D subfamily.
messages: Cytoplasm
messages: Nucleus

1415580:TH
gene id: 1415580:TH
uniprot id: A0A6P7XIR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
messages: axon
messages: perinuclear region

1415580:PHLDA2
gene id: 1415580:PHLDA2
uniprot id: A0A6P7Y1Q9
names: Subcellular Location Annotation
messages: Cytoplasm

1415580:MPV17L
gene id: 1415580:MPV17L
uniprot id: A0A6P7XSF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

1415580:CD248
gene id: 1415580:CD248
uniprot id: A0A6P7ZF29
uniprot id: A0A6P7ZJN4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:MLF1
gene id: 1415580:MLF1
uniprot id: A0A6P7Z6V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLF family.
messages: Cytoplasm

1415580:DDX18
gene id: 1415580:DDX18
uniprot id: A0A6P7YDX8
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.

1415580:GET4
gene id: 1415580:GET4
uniprot id: A0A6P7YSR5
uniprot id: A0A6P7YWP5
names: Similarity
messages: Belongs to the GET4 family.

1415580:ELL
gene id: 1415580:ELL
uniprot id: A0A6P7Z185
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

1415580:LOC115460487
gene id: 1415580:LOC115460487
uniprot id: A0A6P7WSE3
uniprot id: A0A6P7WY81
uniprot id: A0A6P7X0U0
uniprot id: A0A6P7X0U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:VWA1
gene id: 1415580:VWA1
uniprot id: A0A6P7WKK4
uniprot id: A0A6P7WUH0
names: Subcellular Location Annotation
messages: Membrane
messages: basement membrane

1415580:SEMA4D
gene id: 1415580:SEMA4D
uniprot id: A0A6P7X834
uniprot id: A0A6P7XAD9
uniprot id: A0A6P7XFP6
uniprot id: A0A6P7XGS1
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115458247
gene id: 1415580:LOC115458247
uniprot id: A0A6P7X0A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPP enzyme family.
messages: Membrane

1415580:MIEF2
gene id: 1415580:MIEF2
uniprot id: A0A6P7YWQ9
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

1415580:LOC115462697
gene id: 1415580:LOC115462697
uniprot id: A0A6P7WZ76
uniprot id: A0A6P7X5H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

1415580:LOC115475056
gene id: 1415580:LOC115475056
uniprot id: A0A6P7YTQ7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:LAMA4
gene id: 1415580:LAMA4
uniprot id: A0A6P7XPK7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115466390
gene id: 1415580:LOC115466390
uniprot id: A0A6P7XD17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAIF1 family.
messages: Induces apoptosis.
messages: Nucleus

1415580:LOC115473220
gene id: 1415580:LOC115473220
uniprot id: A0A6P7YFQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

1415580:ADIPOR2
gene id: 1415580:ADIPOR2
uniprot id: A0A6P7YRW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

1415580:LOC115474631
gene id: 1415580:LOC115474631
uniprot id: A0A6P7YF49
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

1415580:LOC115478354
gene id: 1415580:LOC115478354
uniprot id: A0A6P7Z2H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

1415580:F12
gene id: 1415580:F12
uniprot id: A0A6P7YWW0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

1415580:LOC115471652
gene id: 1415580:LOC115471652
uniprot id: A0A6P7Y8H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Mitochondrion matrix

1415580:CADM3
gene id: 1415580:CADM3
uniprot id: A0A6P7WZJ3
names: Similarity
messages: Belongs to the nectin family.

1415580:POLR1B
gene id: 1415580:POLR1B
uniprot id: A0A6P7XEJ7
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft.

1415580:LOC115466748
gene id: 1415580:LOC115466748
uniprot id: A0A6P7XEV7
names: Similarity
messages: Belongs to the intermediate filament family.

1415580:KCNE5
gene id: 1415580:KCNE5
uniprot id: A0A6P7YD95
names: Similarity
messages: Belongs to the potassium channel KCNE family.

1415580:DHX9
gene id: 1415580:DHX9
uniprot id: A0A6P7Y1B4
uniprot id: A0A6P7YE31
uniprot id: A0A6P7YES3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DEAH subfamily.
messages: Nucleus

1415580:LOC115459871
gene id: 1415580:LOC115459871
uniprot id: A0A6P7WWM0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1415580:LOC115461071
gene id: 1415580:LOC115461071
uniprot id: A0A6P7X7D0
names: Subcellular Location Annotation
messages: Secreted

1415580:LOC115458232
gene id: 1415580:LOC115458232
uniprot id: A0A6P7WKT2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:POMGNT2
gene id: 1415580:POMGNT2
uniprot id: A0A6P7YGL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 61 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:TIMP3
gene id: 1415580:TIMP3
uniprot id: A0A6P7Z2U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I35 (TIMP) family.
messages: extracellular matrix

1415580:LOC115464988
gene id: 1415580:LOC115464988
uniprot id: A0A6P7XFJ1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:FAM76A
gene id: 1415580:FAM76A
uniprot id: A0A6P7ZLZ3
names: Similarity
messages: Belongs to the FAM76 family.

1415580:LOC115465528
gene id: 1415580:LOC115465528
uniprot id: A0A6P7X8J8
uniprot id: A0A6P7XFE6
uniprot id: A0A6P7XHJ1
uniprot id: A0A6P7XMP5
uniprot id: A0A6P7XMP9
uniprot id: A0A6P7XND0
uniprot id: A0A6P7XND5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1415580:LOC115456865
gene id: 1415580:LOC115456865
uniprot id: A0A6P7WVZ4
names: Similarity
messages: Belongs to the FAM131 family.

1415580:REM2
gene id: 1415580:REM2
uniprot id: A0A6P7WZ66
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

1415580:SERPINF1
gene id: 1415580:SERPINF1
uniprot id: A0A6P7WTG8
names: Similarity
messages: Belongs to the serpin family.

1415580:ACE2
gene id: 1415580:ACE2
uniprot id: A0A6P7Y5Z2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase M2 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Membrane
messages: Secreted
messages: cilium

1415580:LOC115456558
gene id: 1415580:LOC115456558
uniprot id: A0A6P7WTN7
names: Subcellular Location Annotation
messages: Membrane

1415580:THBD
gene id: 1415580:THBD
uniprot id: A0A6P7XND6
names: Function
names: Subunit
messages: Interacts with ITGAL, ITGAM and ITGB2.
messages: Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.

1415580:NIPA2
gene id: 1415580:NIPA2
uniprot id: A0A6P7XAM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

1415580:NCAPH2
gene id: 1415580:NCAPH2
uniprot id: A0A6P7Z8P2
names: Similarity
messages: Belongs to the CND2 H2 (condensin-2 subunit 2) family.

1415580:ORMDL1
gene id: 1415580:ORMDL1
uniprot id: A0A6P7YCR4
uniprot id: A0A6P7YPW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

1415580:MIDN
gene id: 1415580:MIDN
uniprot id: A0A6P7Z843
uniprot id: A0A6P7ZE64
names: Subcellular Location Annotation
messages: Nucleus

1415580:CWF19L1
gene id: 1415580:CWF19L1
uniprot id: A0A6P7Z4T3
names: Similarity
messages: Belongs to the CWF19 family.

1415580:ERBB4
gene id: 1415580:ERBB4
uniprot id: A0A6P7YPL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

1415580:PCBD1
gene id: 1415580:PCBD1
uniprot id: A0A6P7XUY9
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1415580:LOC115459834
gene id: 1415580:LOC115459834
uniprot id: A0A6P7X4J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M67A family. CSN5 subfamily.
messages: synaptic vesicle

1415580:LOC115482595
gene id: 1415580:LOC115482595
uniprot id: A0A6P7ZNE8
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

1415580:CPSF6
gene id: 1415580:CPSF6
uniprot id: A0A6P7Z3N5
uniprot id: A0A6P7Z7B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Cytoplasm
messages: Nucleus speckle
messages: nucleoplasm

1415580:CD8A
gene id: 1415580:CD8A
uniprot id: A0A6P7X9W7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:SH3GL1
gene id: 1415580:SH3GL1
uniprot id: A0A6P7Z6V9
uniprot id: A0A6P7ZBZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

1415580:LOC115464657
gene id: 1415580:LOC115464657
uniprot id: A0A6P7XEF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115480088
gene id: 1415580:LOC115480088
uniprot id: A0A6P7Z4Z5
uniprot id: A0A6P7ZD31
names: Similarity
messages: Belongs to the cytochrome P450 family.

1415580:ARPP19
gene id: 1415580:ARPP19
uniprot id: A0A6P7WPM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-67 during mitosis, specifically interacts with ppp2r2d (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase.

1415580:SEMA3E
gene id: 1415580:SEMA3E
uniprot id: A0A6P7Z9Y6
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:ATP12A
gene id: 1415580:ATP12A
uniprot id: A0A6P7ZGH7
uniprot id: A0A6P7ZU74
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LOC115476613
gene id: 1415580:LOC115476613
uniprot id: A0A6P7Z0A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCRQ/QCR8 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 11 subunits. The complex is composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein UQCRFS1, 2 core protein subunits UQCRC1/QCR1 and UQCRC2/QCR2, and 6 low-molecular weight protein subunits UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and subunit 9, the cleavage product of Rieske protein UQCRFS1. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and cytochrome c oxidase (complex IV, CIV), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)). Interacts with BRAWNIN.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

1415580:IPO5
gene id: 1415580:IPO5
uniprot id: A0A6P7XPD4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

1415580:RPL3
gene id: 1415580:RPL3
uniprot id: A0A6P7YH53
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

1415580:EHHADH
gene id: 1415580:EHHADH
uniprot id: A0A6P7YBF2
uniprot id: A0A6P7YII9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1415580:LOC115476505
gene id: 1415580:LOC115476505
uniprot id: A0A6P7YN79
names: Similarity
messages: Belongs to the globin family.

1415580:NUDT21
gene id: 1415580:NUDT21
uniprot id: A0A6P7Y9Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family. CPSF5 subfamily.
messages: Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.
messages: Cytoplasm
messages: Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.
messages: Nucleus

1415580:USP12
gene id: 1415580:USP12
uniprot id: A0A6P7XS70
names: Similarity
messages: Belongs to the peptidase C19 family.

1415580:MTOR
gene id: 1415580:MTOR
uniprot id: A0A6P7WKB1
names: Similarity
messages: Belongs to the PI3/PI4-kinase family.

1415580:LOC115471082
gene id: 1415580:LOC115471082
uniprot id: A0A6P7XZ18
uniprot id: A0A6P7Y6M1
uniprot id: A0A6P7YCR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

1415580:SF1
gene id: 1415580:SF1
uniprot id: A0A6P7Z840
uniprot id: A0A6P7ZGP8
uniprot id: A0A6P7ZL69
uniprot id: A0A6P7ZNE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBP/SF1 family.
messages: Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.
messages: Nucleus

1415580:ELK1
gene id: 1415580:ELK1
uniprot id: A0A6P7X740
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

1415580:LOC115481140
gene id: 1415580:LOC115481140
uniprot id: A0A6P7Z9N8
uniprot id: A0A6P7ZJU5
uniprot id: A0A6P7ZNN4
uniprot id: A0A6P7ZQT5
names: Similarity
messages: Belongs to the nesprin family.

1415580:IQSEC1
gene id: 1415580:IQSEC1
uniprot id: A0A6P7Y9M0
uniprot id: A0A6P7YGM4
uniprot id: A0A6P7YGU5
uniprot id: A0A6P7YM21
uniprot id: A0A6P7YM88
names: Similarity
messages: Belongs to the BRAG family.

1415580:NSRP1
gene id: 1415580:NSRP1
uniprot id: A0A6P7WEJ6
uniprot id: A0A6P7WUM7
names: Similarity
messages: Belongs to the NSRP1 family.

1415580:SLC25A40
gene id: 1415580:SLC25A40
uniprot id: A0A6P7X5F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1415580:GTPBP4
gene id: 1415580:GTPBP4
uniprot id: A0A6P7XNJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

1415580:LOC115481749
gene id: 1415580:LOC115481749
uniprot id: A0A6P7ZGF3
names: Similarity
messages: Belongs to the MS4A family.

1415580:LOC115464768
gene id: 1415580:LOC115464768
uniprot id: A0A6P7X5V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

1415580:SLAIN2
gene id: 1415580:SLAIN2
uniprot id: A0A6P7WVK8
uniprot id: A0A6P7X1H6
names: Similarity
messages: Belongs to the SLAIN motif-containing family.

1415580:ONECUT1
gene id: 1415580:ONECUT1
uniprot id: A0A6P7X4P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

1415580:GALC
gene id: 1415580:GALC
uniprot id: A0A6P7YRU8
uniprot id: A0A6P7Z384
names: Similarity
messages: Belongs to the glycosyl hydrolase 59 family.

1415580:LOC115480261
gene id: 1415580:LOC115480261
uniprot id: A0A6P7ZDV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

1415580:GUCY2D
gene id: 1415580:GUCY2D
uniprot id: A0A6P7WWK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane
messages: Photoreceptor outer segment membrane

1415580:PDHX
gene id: 1415580:PDHX
uniprot id: A0A6P7XUI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Mitochondrion matrix

1415580:LIG3
gene id: 1415580:LIG3
uniprot id: A0A6P7ZWB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

1415580:PTPRD
gene id: 1415580:PTPRD
uniprot id: A0A6P7X3J5
uniprot id: A0A6P7X3K0
uniprot id: A0A6P7XA25
uniprot id: A0A6P7XA30
uniprot id: A0A6P7XC99
uniprot id: A0A6P7XCA4
uniprot id: A0A6P7XCA9
uniprot id: A0A6P7XHK5
uniprot id: A0A6P7XHL1
uniprot id: A0A6P7XHL6
uniprot id: A0A6P7XIP5
uniprot id: A0A6P7XIQ0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.

1415580:LOC115457395
gene id: 1415580:LOC115457395
uniprot id: A0A6P7WHC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115464384
gene id: 1415580:LOC115464384
uniprot id: A0A6P7XJZ2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:SYF2
gene id: 1415580:SYF2
uniprot id: A0A6P7XXE6
uniprot id: A0A6P7Y2H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYF2 family.
messages: Involved in pre-mRNA splicing.
messages: May be part of a spliceosome complex.
messages: Nucleus

1415580:DOCK3
gene id: 1415580:DOCK3
uniprot id: A0A6P7Y547
names: Similarity
messages: Belongs to the DOCK family.

1415580:CLDN2
gene id: 1415580:CLDN2
uniprot id: A0A6P7YCU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

1415580:TRAK1
gene id: 1415580:TRAK1
uniprot id: A0A6P7Y221
uniprot id: A0A6P7Y7S9
uniprot id: A0A6P7Y8N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the milton family.
messages: Early endosome
messages: Mitochondrion

1415580:DAZAP2
gene id: 1415580:DAZAP2
uniprot id: A0A6P7XLS5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus speckle
messages: nuclear body

1415580:RNF8
gene id: 1415580:RNF8
uniprot id: A0A6P7X7T3
uniprot id: A0A6P7XEI2
uniprot id: A0A6P7XGM3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CHFR family.
messages: Belongs to the RNF8 family.
messages: E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53BP1 and BRCA1 ionizing radiation-induced foci (IRIF). H2A ubiquitination also mediates the ATM-dependent transcriptional silencing at regions flanking DSBs in cis, a mechanism to avoid collision between transcription and repair intermediates. Also catalyzes the formation of 'Lys-48'-linked polyubiquitin chains, leading to degradation of substrate proteins. In addition to its function in damage signaling, also plays a role in higher-order chromatin structure by mediating extensive chromatin decondensation.
messages: Homodimer. Forms a E2-E3 ubiquitin ligase complex composed of the RNF8 homodimer and a E2 heterodimer of UBE2N and UBE2V2.
messages: Nucleus
messages: The FHA domain specifically recognizes and binds ATM-phosphorylated MDC1.

1415580:ST18
gene id: 1415580:ST18
uniprot id: A0A6P7X606
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

1415580:LOC115472971
gene id: 1415580:LOC115472971
uniprot id: A0A6P7YEM0
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

1415580:CTTNBP2
gene id: 1415580:CTTNBP2
uniprot id: A0A6P7Z017
names: Subcellular Location Annotation
messages: cell cortex
messages: dendritic spine

1415580:HTR6
gene id: 1415580:HTR6
uniprot id: A0A6P7ZVE7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:STX16
gene id: 1415580:STX16
uniprot id: A0A6P7YJF7
uniprot id: A0A6P7YRH7
uniprot id: A0A6P7YS83
uniprot id: A0A6P7YW50
names: Similarity
messages: Belongs to the syntaxin family.

1415580:LOC115476389
gene id: 1415580:LOC115476389
uniprot id: A0A6P7YMN5
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

1415580:AVPR1B
gene id: 1415580:AVPR1B
uniprot id: A0A6P7ZTL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

1415580:NOS1
gene id: 1415580:NOS1
uniprot id: A0A6P7ZLP2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOS family.
messages: Binds 1 FAD.
messages: Binds 1 FMN.
messages: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.
messages: dendritic spine
messages: sarcolemma

1415580:LYRM9
gene id: 1415580:LYRM9
uniprot id: A0A6P7ZNN1
uniprot id: A0A6P7ZXD2
names: Similarity
messages: Belongs to the complex I LYR family. LYRM9 subfamily.

1415580:LOC115465826
gene id: 1415580:LOC115465826
uniprot id: A0A6P7XA75
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

1415580:LOC115479312
gene id: 1415580:LOC115479312
uniprot id: A0A6P7Z6C0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:ZDHHC18
gene id: 1415580:ZDHHC18
uniprot id: A0A6P7Z2P1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

1415580:TK2
gene id: 1415580:TK2
uniprot id: A0A6P7YBD0
names: Similarity
messages: Belongs to the DCK/DGK family.

1415580:NUP205
gene id: 1415580:NUP205
uniprot id: A0A6P7Z3P1
names: Similarity
messages: Belongs to the NUP186/NUP192/NUP205 family.

1415580:LOC115463518
gene id: 1415580:LOC115463518
uniprot id: A0A6P7X9G9
uniprot id: A0A6P7XH18
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

1415580:CCNG2
gene id: 1415580:CCNG2
uniprot id: A0A6P7X8D3
names: Similarity
messages: Belongs to the cyclin family.

1415580:ALDH1A1
gene id: 1415580:ALDH1A1
uniprot id: A0A6P7XB47
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1415580:WT1
gene id: 1415580:WT1
uniprot id: A0A6P7XMD9
uniprot id: A0A6P7XU50
uniprot id: A0A6P7Y0G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Cytoplasm
messages: Nucleus speckle

1415580:LOC115476901
gene id: 1415580:LOC115476901
uniprot id: A0A6P7Z1K4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

1415580:FGFR1
gene id: 1415580:FGFR1
uniprot id: A0A6P7XQV8
uniprot id: A0A6P7XQW4
uniprot id: A0A6P7XXV4
uniprot id: A0A6P7XXW0
uniprot id: A0A6P7XYW8
uniprot id: A0A6P7Y3Z6
uniprot id: A0A6P7Y4U7
uniprot id: A0A6P7Y4V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Membrane
messages: Nucleus
messages: Vesicle
messages: cytosol

1415580:RAMP1
gene id: 1415580:RAMP1
uniprot id: A0A6P7YKE4
names: Similarity
messages: Belongs to the RAMP family.

1415580:LOC115469273
gene id: 1415580:LOC115469273
uniprot id: A0A6P7XYH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.

1415580:EMC1
gene id: 1415580:EMC1
uniprot id: A0A6P7ZZU8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC1 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:ITGA7
gene id: 1415580:ITGA7
uniprot id: A0A6P7XAN9
uniprot id: A0A6P7XHH1
uniprot id: A0A6P7XJJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

1415580:PIR
gene id: 1415580:PIR
uniprot id: A0A6P7Y042
names: Similarity
messages: Belongs to the pirin family.

1415580:TRAF3
gene id: 1415580:TRAF3
uniprot id: A0A6P7Z555
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

1415580:TMEM229B
gene id: 1415580:TMEM229B
uniprot id: A0A6P7YR57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM229 family.
messages: Membrane

1415580:GMPR2
gene id: 1415580:GMPR2
uniprot id: A0A6P7WY15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

1415580:NDFIP1
gene id: 1415580:NDFIP1
uniprot id: A0A6P7Z0L0
names: Subcellular Location Annotation
messages: Membrane

1415580:LARS2
gene id: 1415580:LARS2
uniprot id: A0A6P7Y8P1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1415580:LOC115474854
gene id: 1415580:LOC115474854
uniprot id: A0A6P7YT44
names: Subcellular Location Annotation
messages: Membrane

1415580:ERAP1
gene id: 1415580:ERAP1
uniprot id: A0A6P7XG91
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1415580:CASC1
gene id: 1415580:CASC1
uniprot id: A0A6P7YRL5
uniprot id: A0A6P7YY43
uniprot id: A0A6P7YZA0
uniprot id: A0A6P7Z244
uniprot id: A0A6P7Z249
uniprot id: A0A6P7Z323
names: Similarity
messages: Belongs to the DNAI7 family.

1415580:SCG3
gene id: 1415580:SCG3
uniprot id: A0A6P7WQ02
names: Subcellular Location Annotation
messages: Membrane
messages: Secreted
messages: secretory vesicle membrane

1415580:LOC115459876
gene id: 1415580:LOC115459876
uniprot id: A0A6P7X5Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

1415580:LOC115476024
gene id: 1415580:LOC115476024
uniprot id: A0A6P7YTK8
names: Function
names: Similarity
messages: Belongs to the CMP-Neu5Ac hydroxylase family.
messages: Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell-pathogen interactions. Catalyzes the conversion of CMP-N-acetylneuraminic acid (CMP-Neu5Ac) into its hydroxylated derivative CMP-N-glycolylneuraminic acid (CMP-Neu5Gc), a sialic acid abundantly expressed at the surface of many cells.

1415580:LOC115470365
gene id: 1415580:LOC115470365
uniprot id: A0A6P7XV47
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

1415580:MAF
gene id: 1415580:MAF
uniprot id: A0A6P7XY80
uniprot id: A0A6P7Y5X8
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

1415580:CACNA2D1
gene id: 1415580:CACNA2D1
uniprot id: A0A6P7ZC65
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

1415580:LOC115477140
gene id: 1415580:LOC115477140
uniprot id: A0A6P7YQU8
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

1415580:LOC115467085
gene id: 1415580:LOC115467085
uniprot id: A0A6P7XGJ1
uniprot id: A0A6P7XQ18
uniprot id: A0A6P7XVY3
names: Similarity
messages: Belongs to the RCAN family.

1415580:MRPL42
gene id: 1415580:MRPL42
uniprot id: A0A6P7Z4W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL42 family.
messages: Mitochondrion

1415580:RAP2C
gene id: 1415580:RAP2C
uniprot id: A0A6P7YJ72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

1415580:MAPT
gene id: 1415580:MAPT
uniprot id: A0A6P7ZBB8
uniprot id: A0A6P7ZFL2
uniprot id: A0A6P7ZNL6
uniprot id: A0A6P7ZNM1
uniprot id: A0A6P7ZS23
uniprot id: A0A6P7ZUD3
uniprot id: A0A6P7ZUE3
names: Subcellular Location Annotation
messages: cytoskeleton

1415580:LOC115460510
gene id: 1415580:LOC115460510
uniprot id: A0A6P7X0Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115457141
gene id: 1415580:LOC115457141
uniprot id: A0A6P7WPW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:DNMT3A
gene id: 1415580:DNMT3A
uniprot id: A0A6P7XPM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

1415580:TRIT1
gene id: 1415580:TRIT1
uniprot id: A0A6P7ZE89
names: Similarity
messages: Belongs to the IPP transferase family.

1415580:HMCES
gene id: 1415580:HMCES
uniprot id: A0A6P7YCC6
uniprot id: A0A6P7YHS0
names: Function
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.
messages: Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA: forms a stable thiazolidine linkage between a ring-opened abasic site and the alpha-amino and sulfhydryl substituents of its N-terminal catalytic cysteine residue. The HMCES DNA-protein cross-link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endonucleases that are error-prone and would generate mutations and double-strand breaks. Has preference for ssDNA, but can also accommodate double-stranded DNA with 3' or 5' overhang (dsDNA), and dsDNA-ssDNA 3' junction.

1415580:SERF2
gene id: 1415580:SERF2
uniprot id: A0A6P7X6S3
names: Similarity
messages: Belongs to the SERF family.

1415580:LOC115457400
gene id: 1415580:LOC115457400
uniprot id: A0A6P7WQN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:DUSP10
gene id: 1415580:DUSP10
uniprot id: A0A6P7XF85
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

1415580:LOC115470979
gene id: 1415580:LOC115470979
uniprot id: A0A6P7Y699
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

1415580:PATL2
gene id: 1415580:PATL2
uniprot id: A0A6P7YD46
uniprot id: A0A6P7YKA4
uniprot id: A0A6P7YKT5
names: Similarity
messages: Belongs to the PAT1 family.

1415580:SLC20A1
gene id: 1415580:SLC20A1
uniprot id: A0A6P7XX71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.

1415580:LOC115481453
gene id: 1415580:LOC115481453
uniprot id: A0A6P7ZTC4
names: Similarity
messages: Belongs to the intermediate filament family.

1415580:CAMK2D
gene id: 1415580:CAMK2D
uniprot id: A0A6P7WU33
uniprot id: A0A6P7WU37
uniprot id: A0A6P7WU42
uniprot id: A0A6P7WU47
uniprot id: A0A6P7WZW7
uniprot id: A0A6P7WZX2
uniprot id: A0A6P7X2J2
uniprot id: A0A6P7X2J7
uniprot id: A0A6P7X2K4
uniprot id: A0A6P7X7X5
uniprot id: A0A6P7X7X9
uniprot id: A0A6P7X7Y3
uniprot id: A0A6P7X9A3
uniprot id: A0A6P7X9A8
uniprot id: A0A6P7X9B3
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

1415580:CFAP53
gene id: 1415580:CFAP53
uniprot id: A0A6P7X5Q7
names: Similarity
messages: Belongs to the CFAP53 family.

1415580:PHKA1
gene id: 1415580:PHKA1
uniprot id: A0A6P7YSB4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

1415580:HTR7
gene id: 1415580:HTR7
uniprot id: A0A6P7XZ90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:BBS10
gene id: 1415580:BBS10
uniprot id: A0A6P7Z3N4
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

1415580:LOC115476416
gene id: 1415580:LOC115476416
uniprot id: A0A6P7YVJ4
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

1415580:GDF15
gene id: 1415580:GDF15
uniprot id: A0A6P7ZPB2
names: Similarity
messages: Belongs to the TGF-beta family.

1415580:LOC115460715
gene id: 1415580:LOC115460715
uniprot id: A0A6P7X1J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:DTNA
gene id: 1415580:DTNA
uniprot id: A0A6P7YRR9
uniprot id: A0A6P7YY61
uniprot id: A0A6P7YYD2
uniprot id: A0A6P7YZC7
uniprot id: A0A6P7YZD6
uniprot id: A0A6P7YZF8
uniprot id: A0A6P7YZH3
uniprot id: A0A6P7Z2D7
uniprot id: A0A6P7Z355
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dystrophin family. Dystrobrevin subfamily.
messages: Cytoplasm

1415580:FAM161B
gene id: 1415580:FAM161B
uniprot id: A0A6P7Z6B9
names: Similarity
messages: Belongs to the FAM161 family.

1415580:ATP8A2
gene id: 1415580:ATP8A2
uniprot id: A0A6P7XZF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

1415580:LOC115473968
gene id: 1415580:LOC115473968
uniprot id: A0A6P7YPA2
names: Subcellular Location Annotation
messages: cytoskeleton

1415580:FBXO25
gene id: 1415580:FBXO25
uniprot id: A0A6P7XVT6
uniprot id: A0A6P7XWF2
names: Subcellular Location Annotation
messages: Nucleus

1415580:BAMBI
gene id: 1415580:BAMBI
uniprot id: A0A6P7XPQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BAMBI family.
messages: Membrane
messages: Negatively regulates TGF-beta signaling.

1415580:ARCN1
gene id: 1415580:ARCN1
uniprot id: A0A6P7ZG51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

1415580:LOC115457168
gene id: 1415580:LOC115457168
uniprot id: A0A6P7WN25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:TRPC6
gene id: 1415580:TRPC6
uniprot id: A0A6P7XU94
names: Subcellular Location Annotation
messages: Membrane

1415580:AVIL
gene id: 1415580:AVIL
uniprot id: A0A6P7XU20
names: Similarity
messages: Belongs to the villin/gelsolin family.

1415580:LOC115480735
gene id: 1415580:LOC115480735
uniprot id: A0A6P7ZGH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

1415580:SMIM5
gene id: 1415580:SMIM5
uniprot id: A0A6P7YGP6
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115480524
gene id: 1415580:LOC115480524
uniprot id: A0A6P7ZFF7
names: Similarity
messages: Belongs to the peptidase C1 family.

1415580:MEAF6
gene id: 1415580:MEAF6
uniprot id: A0A6P7ZEH0
uniprot id: A0A6P7ZIA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EAF6 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
messages: Component of the NuA4 histone acetyltransferase complex. Component of the hbo1 complex. Component of the moz/morf complex.
messages: kinetochore
messages: nucleolus

1415580:LOC115474619
gene id: 1415580:LOC115474619
uniprot id: A0A6P7YMN3
names: Function
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Metallothioneins have a high content of cysteine residues that bind various heavy metals.

1415580:LOC115474270
gene id: 1415580:LOC115474270
uniprot id: A0A6P7YL53
names: Similarity
messages: Belongs to the peptidase C14A family.

1415580:LOC115466141
gene id: 1415580:LOC115466141
uniprot id: A0A6P7XIM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Cytoplasm

1415580:CERS2
gene id: 1415580:CERS2
uniprot id: A0A6P7WR97
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

1415580:TCTN3
gene id: 1415580:TCTN3
uniprot id: A0A6P7YAT0
uniprot id: A0A6P7YHU4
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

1415580:LOC115474989
gene id: 1415580:LOC115474989
uniprot id: A0A6P7YPC2
names: Similarity
messages: Belongs to the SH3BGR family.

1415580:RBX1
gene id: 1415580:RBX1
uniprot id: A0A6P7X5K1
names: Similarity
messages: Belongs to the RING-box family.

1415580:ECHDC2
gene id: 1415580:ECHDC2
uniprot id: A0A6P7Y607
uniprot id: A0A6P7YD48
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1415580:ANXA13
gene id: 1415580:ANXA13
uniprot id: A0A6P7ZAT0
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

1415580:LIPI
gene id: 1415580:LIPI
uniprot id: A0A6P7Y020
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

1415580:LOC115475946
gene id: 1415580:LOC115475946
uniprot id: A0A6P7YKA0
uniprot id: A0A6P7YSD8
names: Similarity
messages: Belongs to the peptidase S10 family.

1415580:S1PR1
gene id: 1415580:S1PR1
uniprot id: A0A6P7YE76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:MED30
gene id: 1415580:MED30
uniprot id: A0A6P7Z4C0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 30 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

1415580:LDLRAD3
gene id: 1415580:LDLRAD3
uniprot id: A0A6P7Y0T0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:COQ10A
gene id: 1415580:COQ10A
uniprot id: A0A6P7XAM5
uniprot id: A0A6P7XQF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

1415580:MRAP
gene id: 1415580:MRAP
uniprot id: A0A6P7Y5H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRAP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:LOC115463416
gene id: 1415580:LOC115463416
uniprot id: A0A6P7XGG2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC3 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

1415580:SFR1
gene id: 1415580:SFR1
uniprot id: A0A6P7Y7D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFR1/MEI5 family.
messages: Nucleus

1415580:LOC115465345
gene id: 1415580:LOC115465345
uniprot id: A0A6P7X7U3
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

1415580:LOC115468109
gene id: 1415580:LOC115468109
uniprot id: A0A6P7XQX6
names: Similarity
messages: Belongs to the nucleoplasmin family.

1415580:SHQ1
gene id: 1415580:SHQ1
uniprot id: A0A6P7YI63
names: Similarity
messages: Belongs to the SHQ1 family.

1415580:SELENOS
gene id: 1415580:SELENOS
uniprot id: A0A6P7WWU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenoprotein S family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:DNM3
gene id: 1415580:DNM3
uniprot id: A0A6P7YMT1
uniprot id: A0A6P7YN76
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

1415580:ARHGEF28
gene id: 1415580:ARHGEF28
uniprot id: A0A6P7XFX9
names: Subcellular Location Annotation
messages: Cytoplasm

1415580:AQP3
gene id: 1415580:AQP3
uniprot id: A0A6P7XDP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

1415580:LOC115479695
gene id: 1415580:LOC115479695
uniprot id: A0A6P7ZAQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

1415580:LOC115458164
gene id: 1415580:LOC115458164
uniprot id: A0A6P7WRS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

1415580:NADSYN1
gene id: 1415580:NADSYN1
uniprot id: A0A6P7XUC4
names: Similarity
names: Subunit
messages: Homohexamer.
messages: In the C-terminal section; belongs to the NAD synthetase family.

1415580:GALNT14
gene id: 1415580:GALNT14
uniprot id: A0A6P7XMV3
uniprot id: A0A6P7XNI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

1415580:LOC115457288
gene id: 1415580:LOC115457288
uniprot id: A0A6P7WND2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:MZT1
gene id: 1415580:MZT1
uniprot id: A0A6P7XV94
names: Function
names: Similarity
messages: Belongs to the MOZART1 family.
messages: Required for gamma-tubulin complex recruitment to the centrosome.

1415580:MCTP2
gene id: 1415580:MCTP2
uniprot id: A0A6P7WWR2
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115461765
gene id: 1415580:LOC115461765
uniprot id: A0A6P7XAR9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:MAGOH
gene id: 1415580:MAGOH
uniprot id: A0A6P7Y312
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mago nashi family.
messages: Nucleus

1415580:LOC115464774
gene id: 1415580:LOC115464774
uniprot id: A0A6P7X5V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

1415580:ATP2B2
gene id: 1415580:ATP2B2
uniprot id: A0A6P7Y0L8
uniprot id: A0A6P7Y855
uniprot id: A0A6P7YDJ7
uniprot id: A0A6P7YE78
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1415580:EPHB3
gene id: 1415580:EPHB3
uniprot id: A0A6P7YY92
uniprot id: A0A6P7Z9K3
names: Subcellular Location Annotation
messages: Membrane

1415580:ANXA9
gene id: 1415580:ANXA9
uniprot id: A0A6P7WYB0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Membrane
messages: basement membrane

1415580:LOC115482576
gene id: 1415580:LOC115482576
uniprot id: A0A6P7ZG66
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

1415580:LOC115476590
gene id: 1415580:LOC115476590
uniprot id: A0A6P7YWE1
uniprot id: A0A6P7YZJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane
messages: Membrane

1415580:LOC115482011
gene id: 1415580:LOC115482011
uniprot id: A0A6P7ZT81
uniprot id: A0A6P7ZV25
uniprot id: A0A6P7ZVU5
names: Similarity
messages: Belongs to the peptidase A1 family.

1415580:LOC115457025
gene id: 1415580:LOC115457025
uniprot id: A0A6P7WVP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115469629
gene id: 1415580:LOC115469629
uniprot id: A0A6P7Y6A8
names: Similarity
messages: Belongs to the helicase family.

1415580:RPRD1A
gene id: 1415580:RPRD1A
uniprot id: A0A6P7YCA2
names: Similarity
messages: Belongs to the UPF0400 (RTT103) family.

1415580:CCHCR1
gene id: 1415580:CCHCR1
uniprot id: A0A6P7XRH8
uniprot id: A0A6P7XS71
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be a regulator of keratinocyte proliferation or differentiation.
messages: Nucleus

1415580:LDHD
gene id: 1415580:LDHD
uniprot id: A0A6P7Y2X3
names: Similarity
messages: Belongs to the FAD-binding oxidoreductase/transferase type 4 family.

1415580:LOC115464602
gene id: 1415580:LOC115464602
uniprot id: A0A6P7XE88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 11 family.
messages: Golgi stack membrane
messages: Membrane

1415580:LOC115477873
gene id: 1415580:LOC115477873
uniprot id: A0A6P7YUK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 7B2 family.
messages: Secreted

1415580:PMF1
gene id: 1415580:PMF1
uniprot id: A0A6P7WV11
names: Subcellular Location Annotation
messages: Nucleus
messages: kinetochore

1415580:DIPK2B
gene id: 1415580:DIPK2B
uniprot id: A0A6P7XXV5
uniprot id: A0A6P7XYK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Secreted

1415580:LOC115465558
gene id: 1415580:LOC115465558
uniprot id: A0A6P7XHN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
messages: lamellipodium

1415580:LOC115469475
gene id: 1415580:LOC115469475
uniprot id: A0A6P7XZP0
names: Similarity
messages: In the C-terminal section; belongs to the GART family.
messages: In the N-terminal section; belongs to the GARS family.
messages: In the central section; belongs to the AIR synthase family.

1415580:RXRA
gene id: 1415580:RXRA
uniprot id: A0A6P7Y7N9
uniprot id: A0A6P7YF25
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

1415580:CNTNAP1
gene id: 1415580:CNTNAP1
uniprot id: A0A6P7ZW67
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: paranodal septate junction

1415580:DBP
gene id: 1415580:DBP
uniprot id: A0A6P7XMB5
uniprot id: A0A6P7XSN1
uniprot id: A0A6P7XTA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

1415580:ACTN1
gene id: 1415580:ACTN1
uniprot id: A0A6P7YXI7
uniprot id: A0A6P7YYN5
uniprot id: A0A6P7Z2F6
names: Similarity
messages: Belongs to the alpha-actinin family.

1415580:SBDS
gene id: 1415580:SBDS
uniprot id: A0A6P7WKU6
names: Function
names: Similarity
messages: Belongs to the SDO1/SBDS family.
messages: Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.

1415580:SLC17A8
gene id: 1415580:SLC17A8
uniprot id: A0A6P7Z0K3
names: Subcellular Location Annotation
messages: Membrane

1415580:LOC115461187
gene id: 1415580:LOC115461187
uniprot id: A0A6P7X7Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:PKNOX1
gene id: 1415580:PKNOX1
uniprot id: A0A6P7Y980
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

1415580:KDM5C
gene id: 1415580:KDM5C
uniprot id: A0A6P7X2U5
uniprot id: A0A6P7X999
uniprot id: A0A6P7XBL8
uniprot id: A0A6P7XGV0
uniprot id: A0A6P7XHY8
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

1415580:GTF2IRD1
gene id: 1415580:GTF2IRD1
uniprot id: A0A6P7WER0
uniprot id: A0A6P7WER5
uniprot id: A0A6P7WKX4
uniprot id: A0A6P7WKX9
uniprot id: A0A6P7WMV9
uniprot id: A0A6P7WTU8
uniprot id: A0A6P7WUV7
names: Subcellular Location Annotation
messages: Nucleus

1415580:PNPLA4
gene id: 1415580:PNPLA4
uniprot id: A0A6P7XQ53
uniprot id: A0A6P7XWZ2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1415580:LCOR
gene id: 1415580:LCOR
uniprot id: A0A6P7Y0T8
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115462513
gene id: 1415580:LOC115462513
uniprot id: A0A6P7XCN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ODAM family.
messages: Cytoplasm
messages: Interacts (via C-terminus) with ARHGEF5.
messages: Nucleus
messages: Secreted
messages: Tooth-associated epithelia protein that probably plays a role in odontogenesis, the complex process that results in the initiation and generation of the tooth. May be incorporated in the enamel matrix at the end of mineralization process. Involved in the induction of RHOA activity via interaction with ARHGEF and expression of downstream factors such as ROCK. Plays a role in attachment of the junctional epithelium to the tooth surface.

1415580:LOC115464560
gene id: 1415580:LOC115464560
uniprot id: A0A6P7XC19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:CHMP1A
gene id: 1415580:CHMP1A
uniprot id: A0A6P7Y672
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF7 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

1415580:LOC115472760
gene id: 1415580:LOC115472760
uniprot id: A0A6P7YIX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

1415580:DDRGK1
gene id: 1415580:DDRGK1
uniprot id: A0A6P7X8I5
uniprot id: A0A6P7X9S4
names: Similarity
messages: Belongs to the DDRGK1 family.

1415580:FGF8
gene id: 1415580:FGF8
uniprot id: A0A6P7YC77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Secreted

1415580:CA4
gene id: 1415580:CA4
uniprot id: A0A6P7WLH0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Cell membrane
messages: Interacts with SLC4A4.
messages: Membrane

1415580:LOC115472718
gene id: 1415580:LOC115472718
uniprot id: A0A6P7Y5Y9
names: Similarity
messages: Belongs to the Luc7 family.

1415580:EDN1
gene id: 1415580:EDN1
uniprot id: A0A6P7YHM9
uniprot id: A0A6P7YQE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

1415580:DCAF13
gene id: 1415580:DCAF13
uniprot id: A0A6P7ZA48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DCAF13/WDSOF1 family.
messages: nucleolus

1415580:UCHL5
gene id: 1415580:UCHL5
uniprot id: A0A6P7Y944
names: Similarity
messages: Belongs to the peptidase C12 family.

1415580:DDIT3
gene id: 1415580:DDIT3
uniprot id: A0A6P7XH12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Cytoplasm

1415580:C8H16orf71
gene id: 1415580:C8H16orf71
uniprot id: A0A6P7YWV9
names: Function
messages: In cyliated cells, dynein axonemal particle-specific protein required for deployment of ODA to the axoneme. Interacts with outer dynein arm (ODA) subunits.

1415580:LOC115466358
gene id: 1415580:LOC115466358
uniprot id: A0A6P7XCW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

1415580:NDUFC2
gene id: 1415580:NDUFC2
uniprot id: A0A6P7XI88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFC2 subunit family.
messages: Mitochondrion inner membrane

1415580:CACNA2D2
gene id: 1415580:CACNA2D2
uniprot id: A0A6P7YIA7
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

1415580:BORCS7
gene id: 1415580:BORCS7
uniprot id: A0A6P7XZ35
uniprot id: A0A6P7YCS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS7 family.
messages: Membrane

1415580:SPRY2
gene id: 1415580:SPRY2
uniprot id: A0A6P7Y0D5
names: Similarity
messages: Belongs to the sprouty family.

1415580:LOC115463480
gene id: 1415580:LOC115463480
uniprot id: A0A6P7XGU1
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

1415580:PARD3
gene id: 1415580:PARD3
uniprot id: A0A6P7XHF0
uniprot id: A0A6P7XP61
uniprot id: A0A6P7XWR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR3 family.
messages: Cell junction
messages: Endomembrane system

1415580:POU6F1
gene id: 1415580:POU6F1
uniprot id: A0A6P7XNL6
uniprot id: A0A6P7XUK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

1415580:OVOL2
gene id: 1415580:OVOL2
uniprot id: A0A6P7X938
uniprot id: A0A6P7XI28
uniprot id: A0A6P7XNW2
names: Subcellular Location Annotation
messages: Nucleus

1415580:LOC115457250
gene id: 1415580:LOC115457250
uniprot id: A0A6P7WGZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115464381
gene id: 1415580:LOC115464381
uniprot id: A0A6P7X4T7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1415580:SLC37A1
gene id: 1415580:SLC37A1
uniprot id: A0A6P7XW28
uniprot id: A0A6P7Y424
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

1415580:DPAGT1
gene id: 1415580:DPAGT1
uniprot id: A0A6P7ZVJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family.
messages: Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol.
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:TRPC5
gene id: 1415580:TRPC5
uniprot id: A0A6P7YQ07
uniprot id: A0A6P7YQD8
names: Subcellular Location Annotation
messages: Membrane

1415580:NCEH1
gene id: 1415580:NCEH1
uniprot id: A0A6P7YZ96
uniprot id: A0A6P7Z748
uniprot id: A0A6P7Z9S0
uniprot id: A0A6P7ZAL5
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

1415580:LOC115462214
gene id: 1415580:LOC115462214
uniprot id: A0A6P7X6K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

1415580:IAH1
gene id: 1415580:IAH1
uniprot id: A0A6P7XW91
names: Function
names: Similarity
messages: Belongs to the 'GDSL' lipolytic enzyme family. IAH1 subfamily.
messages: Probable lipase.

1415580:PDYN
gene id: 1415580:PDYN
uniprot id: A0A6P7YVW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opiod activity, it is 700 times more potent than Leu-enkephalin.
messages: Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress.
messages: Leumorphin has a typical opiod activity and may have anti-apoptotic effect.
messages: Secreted

1415580:LOC115466238
gene id: 1415580:LOC115466238
uniprot id: A0A6P7XJ57
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1415580:LOC115471728
gene id: 1415580:LOC115471728
uniprot id: A0A6P7Y1H9
names: Similarity
messages: Belongs to the folate receptor family.

1415580:LOC115461930
gene id: 1415580:LOC115461930
uniprot id: A0A6P7XBA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:PPP2R2C
gene id: 1415580:PPP2R2C
uniprot id: A0A6P7X3J6
uniprot id: A0A6P7XA79
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

1415580:PIGM
gene id: 1415580:PIGM
uniprot id: A0A6P7YDJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGM family.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly.
messages: Membrane

1415580:LOC115474083
gene id: 1415580:LOC115474083
uniprot id: A0A6P7YCP6
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

1415580:TBX20
gene id: 1415580:TBX20
uniprot id: A0A6P7WRN9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

1415580:SLC6A13
gene id: 1415580:SLC6A13
uniprot id: A0A6P7Z448
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1415580:NGF
gene id: 1415580:NGF
uniprot id: A0A6P7ZGB5
uniprot id: A0A6P7ZV10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Secreted

1415580:KDM3A
gene id: 1415580:KDM3A
uniprot id: A0A6P7X376
names: Subcellular Location Annotation
messages: Nucleus

1415580:SERBP1
gene id: 1415580:SERBP1
uniprot id: A0A6P7Y1P8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

1415580:LOC115457183
gene id: 1415580:LOC115457183
uniprot id: A0A6P7WQ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:LOC115461685
gene id: 1415580:LOC115461685
uniprot id: A0A6P7WWJ7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1415580:LOC115472899
gene id: 1415580:LOC115472899
uniprot id: A0A6P7Y6V8
uniprot id: A0A6P7YDY7
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.

1415580:CCDC39
gene id: 1415580:CCDC39
uniprot id: A0A6P7Z5E8
names: Similarity
messages: Belongs to the CCDC39 family.

1415580:HNF1B
gene id: 1415580:HNF1B
uniprot id: A0A6P7WFU9
uniprot id: A0A6P7WUZ9
uniprot id: A0A6P7WW08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HNF1 homeobox family.
messages: Nucleus

1415580:PFN2
gene id: 1415580:PFN2
uniprot id: A0A6P7ZB20
uniprot id: A0A6P7ZBU2
names: Function
names: Similarity
messages: Belongs to the profilin family.
messages: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.

1415580:LOC115458141
gene id: 1415580:LOC115458141
uniprot id: A0A6P7WKI8
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

1415580:SEPTIN3
gene id: 1415580:SEPTIN3
uniprot id: A0A6P7X017
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cytoplasm

1415580:SPTLC2
gene id: 1415580:SPTLC2
uniprot id: A0A6P7Z233
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1415580:GRIA1
gene id: 1415580:GRIA1
uniprot id: A0A6P7YIZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

1415580:LOC115480243
gene id: 1415580:LOC115480243
uniprot id: A0A6P7ZGD1
names: Similarity
messages: Belongs to the bZIP family. NFIL3 subfamily.

1415580:WSCD2
gene id: 1415580:WSCD2
uniprot id: A0A6P7ZP35
names: Similarity
messages: Belongs to the WSCD family.

1415580:NSFL1C
gene id: 1415580:NSFL1C
uniprot id: A0A6P7YR72
names: Subcellular Location Annotation
messages: Golgi stack

1415580:HNRNPD
gene id: 1415580:HNRNPD
uniprot id: A0A6P7WTF4
uniprot id: A0A6P7WZ85
uniprot id: A0A6P7X8H7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

1415580:SLC66A3
gene id: 1415580:SLC66A3
uniprot id: A0A6P7XW67
names: Subcellular Location Annotation
messages: Membrane

1415580:KCNK1
gene id: 1415580:KCNK1
uniprot id: A0A6P7XEL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: Recycling endosome
messages: Synaptic cell membrane
messages: Vesicle
messages: dendrite

1415580:LOC115461542
gene id: 1415580:LOC115461542
uniprot id: A0A6P7WVR1
uniprot id: A0A6P7WVR7
uniprot id: A0A6P7X1N5
uniprot id: A0A6P7X1P0
uniprot id: A0A6P7X496
uniprot id: A0A6P7X4A2
uniprot id: A0A6P7X4A8
uniprot id: A0A6P7X9M3
uniprot id: A0A6P7XAX5
names: Similarity
names: Subunit
messages: Homooctamer.
messages: In the C-terminal section; belongs to the AIR carboxylase family. Class II subfamily.
messages: In the N-terminal section; belongs to the SAICAR synthetase family.

1415580:FOXP1
gene id: 1415580:FOXP1
uniprot id: A0A6P7Y8W8
uniprot id: A0A6P7YG92
uniprot id: A0A6P7YLD1
uniprot id: A0A6P7YLD5
uniprot id: A0A6P7YLM0
names: Subcellular Location Annotation
messages: Nucleus

1415580:BLMH
gene id: 1415580:BLMH
uniprot id: A0A6P7ZVT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Cytoplasm

1415580:MMGT1
gene id: 1415580:MMGT1
uniprot id: A0A6P7YPD9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane magnesium transporter (TC 1.A.67) family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. May be involved in Mg(2+) transport.

1415580:CREB3L4
gene id: 1415580:CREB3L4
uniprot id: A0A6P7WV82
uniprot id: A0A6P7X148
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:LOC115471039
gene id: 1415580:LOC115471039
uniprot id: A0A6P7XYW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shootin family.
messages: axon
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

1415580:BMPR1B
gene id: 1415580:BMPR1B
uniprot id: A0A6P7X7L8
uniprot id: A0A6P7X8X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

1415580:PURA
gene id: 1415580:PURA
uniprot id: A0A6P7YSQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

1415580:CPLX2
gene id: 1415580:CPLX2
uniprot id: A0A6P7YUL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

1415580:DYNC1I2
gene id: 1415580:DYNC1I2
uniprot id: A0A6P7YIS2
uniprot id: A0A6P7YNL3
names: Similarity
messages: Belongs to the dynein intermediate chain family.

1415580:TSHZ3
gene id: 1415580:TSHZ3
uniprot id: A0A6P7Y5N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.
messages: Nucleus

1415580:RAB3GAP1
gene id: 1415580:RAB3GAP1
uniprot id: A0A6P7YP66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab3-GAP catalytic subunit family.
messages: Cytoplasm

1415580:LOC115468512
gene id: 1415580:LOC115468512
uniprot id: A0A6P7XSW6
names: Similarity
messages: Belongs to the TCP10 family.

1415580:LOC115469447
gene id: 1415580:LOC115469447
uniprot id: A0A6P7XRF5
uniprot id: A0A6P7Y5E5
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1415580:LOC115477934
gene id: 1415580:LOC115477934
uniprot id: A0A6P7Z118
uniprot id: A0A6P7Z5C2
uniprot id: A0A6P7Z697
names: Similarity
messages: Belongs to the ARTD/PARP family.

1415580:LOC115474875
gene id: 1415580:LOC115474875
uniprot id: A0A6P7YNV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Late endosome
messages: Lysosome
messages: Membrane

1415580:MRPL15
gene id: 1415580:MRPL15
uniprot id: A0A6P7WXX3
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

1415580:LOC115475045
gene id: 1415580:LOC115475045
uniprot id: A0A6P7YGT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:VPS11
gene id: 1415580:VPS11
uniprot id: A0A6P7ZGZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS11 family.
messages: Cytoplasmic vesicle
messages: Early endosome
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes.
messages: autophagosome
messages: clathrin-coated vesicle

1415580:LOC115474994
gene id: 1415580:LOC115474994
uniprot id: A0A6P7YTJ5
names: Similarity
messages: Belongs to the EVA1 family.

1415580:DNAJC2
gene id: 1415580:DNAJC2
uniprot id: A0A6P7ZA10
names: Subcellular Location Annotation
messages: cytosol

1415580:LOC115465997
gene id: 1415580:LOC115465997
uniprot id: A0A6P7XB31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF4 family.
messages: Membrane

1415580:LOC115457557
gene id: 1415580:LOC115457557
uniprot id: A0A6P7WHW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

1415580:DHCR7
gene id: 1415580:DHCR7
uniprot id: A0A6P7XMK4
uniprot id: A0A6P7Y0M7
uniprot id: A0A6P7Y189
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

1415580:PPIH
gene id: 1415580:PPIH
uniprot id: A0A6P7WKG0
uniprot id: A0A6P7WUD2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1415580:LOC115465326
gene id: 1415580:LOC115465326
uniprot id: A0A6P7X7S3
uniprot id: A0A6P7XLS2
uniprot id: A0A6P7XMJ9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

1415580:LOC115466843
gene id: 1415580:LOC115466843
uniprot id: A0A6P7XFC8
uniprot id: A0A6P7XUV1
names: Subcellular Location Annotation
messages: Nucleus

1415580:EBPL
gene id: 1415580:EBPL
uniprot id: A0A6P7XX59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1415580:CHPT1
gene id: 1415580:CHPT1
uniprot id: A0A6P7Z6C4
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1415580:FGF4
gene id: 1415580:FGF4
uniprot id: A0A6P7XXA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Secreted

1415580:FNIP1
gene id: 1415580:FNIP1
uniprot id: A0A6P7YMJ7
uniprot id: A0A6P7YUC0
uniprot id: A0A6P7YVB6
uniprot id: A0A6P7YYL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNIP family.
messages: Lysosome membrane
messages: Membrane

1415580:LOC115480964
gene id: 1415580:LOC115480964
uniprot id: A0A6P7ZDH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1415580:RNF157
gene id: 1415580:RNF157
uniprot id: A0A6P7Y9B4
uniprot id: A0A6P7YGB1
uniprot id: A0A6P7YGB7
uniprot id: A0A6P7YGL0
uniprot id: A0A6P7YLS8
uniprot id: A0A6P7YLZ6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin ligase.

1415580:CHRNA2
gene id: 1415580:CHRNA2
uniprot id: A0A6P7XL78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

1415580:LOC115464260
gene id: 1415580:LOC115464260
uniprot id: A0A6P7XIM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily.
messages: Membrane

1415580:ADAMTS6
gene id: 1415580:ADAMTS6
uniprot id: A0A6P7X974
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix