1411621:AUC43 RS17225
gene id: 1411621:AUC43_RS17225
uniprot id: A0A0U4CEU0
names: Similarity
messages: Belongs to the universal stress protein A family.

1411621:AUC43 RS03670
gene id: 1411621:AUC43_RS03670
uniprot id: A0A0U3SUS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1411621:AUC43 RS12560
gene id: 1411621:AUC43_RS12560
uniprot id: A0A0U4ACC1
names: Similarity
messages: Belongs to the SCO1/2 family.

1411621:AUC43 RS09740
gene id: 1411621:AUC43_RS09740
uniprot id: A0A0U4BPK0
names: Similarity
messages: Belongs to the peptidase M24B family.

1411621:AUC43 RS01650
gene id: 1411621:AUC43_RS01650
uniprot id: A0A0U4AK12
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1411621:AUC43 RS04260
gene id: 1411621:AUC43_RS04260
uniprot id: A0A0U4C056
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1411621:AUC43 RS08960
gene id: 1411621:AUC43_RS08960
uniprot id: A0A0U4AWU1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1411621:AUC43 RS08060
gene id: 1411621:AUC43_RS08060
uniprot id: A0A0U4C4B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1411621:AUC43 RS11635
gene id: 1411621:AUC43_RS11635
uniprot id: A0A0U4BZL9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1411621:AUC43 RS06100
gene id: 1411621:AUC43_RS06100
uniprot id: A0A0U4AM87
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS02250
gene id: 1411621:AUC43_RS02250
uniprot id: A0A0U4AKK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1411621:AUC43 RS17025
gene id: 1411621:AUC43_RS17025
uniprot id: A0A0U3T173
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 67 family.
messages: Homodimer.

1411621:AUC43 RS07205
gene id: 1411621:AUC43_RS07205
uniprot id: A0A0U4AMV1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1411621:AUC43 RS13055
gene id: 1411621:AUC43_RS13055
uniprot id: A0A0U3SMF0
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

1411621:AUC43 RS18715
gene id: 1411621:AUC43_RS18715
uniprot id: A0A0U3T1Y8
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS00785
gene id: 1411621:AUC43_RS00785
uniprot id: A0A0U4BJZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1411621:AUC43 RS09415
gene id: 1411621:AUC43_RS09415
uniprot id: A0A0U4AAU9
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1411621:AUC43 RS09425
gene id: 1411621:AUC43_RS09425
uniprot id: A0A0U4CPJ0
names: Similarity
messages: Belongs to the SusD family.

1411621:AUC43 RS17610
gene id: 1411621:AUC43_RS17610
uniprot id: A0A0U4AEV1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1411621:AUC43 RS07995
gene id: 1411621:AUC43_RS07995
uniprot id: A0A0U4AWD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1411621:AUC43 RS14555
gene id: 1411621:AUC43_RS14555
uniprot id: A0A0U4BR50
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1411621:AUC43 RS08100
gene id: 1411621:AUC43_RS08100
uniprot id: A0A0U4AGA8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1411621:AUC43 RS01095
gene id: 1411621:AUC43_RS01095
uniprot id: A0A0U4A6G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1411621:AUC43 RS19635
gene id: 1411621:AUC43_RS19635
uniprot id: A0A0U4AUF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1411621:AUC43 RS08075
gene id: 1411621:AUC43_RS08075
uniprot id: A0A0U4BEP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1411621:AUC43 RS18260
gene id: 1411621:AUC43_RS18260
uniprot id: A0A0U4CTU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1411621:AUC43 RS14055
gene id: 1411621:AUC43_RS14055
uniprot id: A0A0U3SJ21
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1411621:AUC43 RS04960
gene id: 1411621:AUC43_RS04960
uniprot id: A0A0U4BLA6
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1411621:AUC43 RS02125
gene id: 1411621:AUC43_RS02125
uniprot id: A0A0U4AG10
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS13465
gene id: 1411621:AUC43_RS13465
uniprot id: A0A0U4BRF5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1411621:AUC43 RS00320
gene id: 1411621:AUC43_RS00320
uniprot id: A0A0U4BY96
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1411621:AUC43 RS09220
gene id: 1411621:AUC43_RS09220
uniprot id: A0A0U4AAR8
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

1411621:AUC43 RS10265
gene id: 1411621:AUC43_RS10265
uniprot id: A0A0U4APG8
names: Similarity
messages: Belongs to the SusD family.

1411621:AUC43 RS17530
gene id: 1411621:AUC43_RS17530
uniprot id: A0A0U3K298
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1411621:AUC43 RS07950
gene id: 1411621:AUC43_RS07950
uniprot id: A0A0U3SFV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1411621:AUC43 RS03990
gene id: 1411621:AUC43_RS03990
uniprot id: A0A0U3SDU8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS18220
gene id: 1411621:AUC43_RS18220
uniprot id: A0A0U4BVL1
names: Similarity
messages: Belongs to the pirin family.

1411621:AUC43 RS07095
gene id: 1411621:AUC43_RS07095
uniprot id: A0A0U4BE66
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1411621:AUC43 RS00485
gene id: 1411621:AUC43_RS00485
uniprot id: A0A0U4AJF5
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1411621:AUC43 RS09405
gene id: 1411621:AUC43_RS09405
uniprot id: A0A0U4BFF1
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1411621:AUC43 RS03415
gene id: 1411621:AUC43_RS03415
uniprot id: A0A0U4BVD2
names: Similarity
messages: Belongs to the threonine synthase family.

1411621:AUC43 RS16025
gene id: 1411621:AUC43_RS16025
uniprot id: A0A0U4BIS0
names: Similarity
messages: Belongs to the DinB family.

1411621:AUC43 RS04165
gene id: 1411621:AUC43_RS04165
uniprot id: A0A0U4BVT0
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1411621:AUC43 RS12685
gene id: 1411621:AUC43_RS12685
uniprot id: A0A0U4C4B8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1411621:AUC43 RS10150
gene id: 1411621:AUC43_RS10150
uniprot id: A0A0U4APE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1411621:AUC43 RS02085
gene id: 1411621:AUC43_RS02085
uniprot id: A0A0U4C6Y4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1411621:AUC43 RS09870
gene id: 1411621:AUC43_RS09870
uniprot id: A0A0U4AB11
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1411621:AUC43 RS00460
gene id: 1411621:AUC43_RS00460
uniprot id: A0A0U4BAU2
names: Subcellular Location Annotation
messages: Cytoplasm

1411621:AUC43 RS04680
gene id: 1411621:AUC43_RS04680
uniprot id: A0A0U4C8H2
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1411621:AUC43 RS08015
gene id: 1411621:AUC43_RS08015
uniprot id: A0A0U4BXS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1411621:AUC43 RS12335
gene id: 1411621:AUC43_RS12335
uniprot id: A0A0U3SZ32
names: Similarity
messages: Belongs to the peptidase U62 family.

1411621:AUC43 RS13325
gene id: 1411621:AUC43_RS13325
uniprot id: A0A0U4CRF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

1411621:AUC43 RS07180
gene id: 1411621:AUC43_RS07180
uniprot id: A0A0U4BE82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

1411621:AUC43 RS05605
gene id: 1411621:AUC43_RS05605
uniprot id: A0A0U4AV66
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1411621:AUC43 RS01475
gene id: 1411621:AUC43_RS01475
uniprot id: A0A0U4BYU7
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

1411621:AUC43 RS05340
gene id: 1411621:AUC43_RS05340
uniprot id: A0A0U4CMQ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1411621:AUC43 RS09015
gene id: 1411621:AUC43_RS09015
uniprot id: A0A0U4BP77
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1411621:AUC43 RS10650
gene id: 1411621:AUC43_RS10650
uniprot id: A0A0U3SH88
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS11925
gene id: 1411621:AUC43_RS11925
uniprot id: A0A0U3SHY2
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

1411621:AUC43 RS10485
gene id: 1411621:AUC43_RS10485
uniprot id: A0A0U4ABA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1411621:AUC43 RS02630
gene id: 1411621:AUC43_RS02630
uniprot id: A0A0U4BK82
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1411621:AUC43 RS11660
gene id: 1411621:AUC43_RS11660
uniprot id: A0A0U3SMD4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1411621:AUC43 RS05595
gene id: 1411621:AUC43_RS05595
uniprot id: A0A0U4BDF5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS11500
gene id: 1411621:AUC43_RS11500
uniprot id: A0A0U4BGI8
names: Similarity
messages: Belongs to the LOG family.

1411621:AUC43 RS06710
gene id: 1411621:AUC43_RS06710
uniprot id: A0A0U4C1A5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS13170
gene id: 1411621:AUC43_RS13170
uniprot id: A0A0U4BRB6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-53 and Arg-56) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1411621:AUC43 RS07800
gene id: 1411621:AUC43_RS07800
uniprot id: A0A0U4A9Y3
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1411621:AUC43 RS19655
gene id: 1411621:AUC43_RS19655
uniprot id: A0A0U3T2C9
names: Similarity
messages: Belongs to the peptidase M42 family.

1411621:AUC43 RS02580
gene id: 1411621:AUC43_RS02580
uniprot id: A0A0U4BUX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1411621:AUC43 RS13080
gene id: 1411621:AUC43_RS13080
uniprot id: A0A0U4BQD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1411621:AUC43 RS02595
gene id: 1411621:AUC43_RS02595
uniprot id: A0A0U3SD57
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1411621:AUC43 RS08985
gene id: 1411621:AUC43_RS08985
uniprot id: A0A0U4BY87
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1411621:AUC43 RS03620
gene id: 1411621:AUC43_RS03620
uniprot id: A0A0U4C7Y0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS13180
gene id: 1411621:AUC43_RS13180
uniprot id: A0A0U4CCP0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1411621:AUC43 RS08030
gene id: 1411621:AUC43_RS08030
uniprot id: A0A0U3SWW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1411621:AUC43 RS05045
gene id: 1411621:AUC43_RS05045
uniprot id: A0A0U4BD61
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1411621:AUC43 RS09365
gene id: 1411621:AUC43_RS09365
uniprot id: A0A0U4AP15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1411621:AUC43 RS18300
gene id: 1411621:AUC43_RS18300
uniprot id: A0A0U4ATC8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1411621:AUC43 RS06155
gene id: 1411621:AUC43_RS06155
uniprot id: A0A0U4BDP0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1411621:AUC43 RS03150
gene id: 1411621:AUC43_RS03150
uniprot id: A0A0U3SDG0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1411621:AUC43 RS15090
gene id: 1411621:AUC43_RS15090
uniprot id: A0A0U4C5H8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1411621:AUC43 RS19285
gene id: 1411621:AUC43_RS19285
uniprot id: A0A0U4C7T3
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS00475
gene id: 1411621:AUC43_RS00475
uniprot id: A0A0U4CKF3
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1411621:AUC43 RS16920
gene id: 1411621:AUC43_RS16920
uniprot id: A0A0U4C6N7
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

1411621:AUC43 RS10030
gene id: 1411621:AUC43_RS10030
uniprot id: A0A0U4BNP4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1411621:AUC43 RS18640
gene id: 1411621:AUC43_RS18640
uniprot id: A0A0U3SL74
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

1411621:AUC43 RS18700
gene id: 1411621:AUC43_RS18700
uniprot id: A0A0U4ATZ5
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS15830
gene id: 1411621:AUC43_RS15830
uniprot id: A0A0U4CE36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1411621:AUC43 RS16380
gene id: 1411621:AUC43_RS16380
uniprot id: A0A0U3SK11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1411621:AUC43 RS01750
gene id: 1411621:AUC43_RS01750
uniprot id: A0A0U4AK28
names: Similarity
messages: Belongs to the peptidase S41A family.

1411621:AUC43 RS08885
gene id: 1411621:AUC43_RS08885
uniprot id: A0A0U4CP95
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1411621:AUC43 RS18600
gene id: 1411621:AUC43_RS18600
uniprot id: A0A0U4CVI5
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS10110
gene id: 1411621:AUC43_RS10110
uniprot id: A0A0U4C585
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1411621:AUC43 RS06960
gene id: 1411621:AUC43_RS06960
uniprot id: A0A0U4BX86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1411621:AUC43 RS07025
gene id: 1411621:AUC43_RS07025
uniprot id: A0A0U4AVW2
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS06255
gene id: 1411621:AUC43_RS06255
uniprot id: A0A0U3JVU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1411621:AUC43 RS02010
gene id: 1411621:AUC43_RS02010
uniprot id: A0A0U4BJV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1411621:AUC43 RS06825
gene id: 1411621:AUC43_RS06825
uniprot id: A0A0U4C9I9
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS15790
gene id: 1411621:AUC43_RS15790
uniprot id: A0A0U4C1H2
names: Similarity
messages: Belongs to the DNA photolyase family.

1411621:AUC43 RS17120
gene id: 1411621:AUC43_RS17120
uniprot id: A0A0U3SKC7
names: Similarity
messages: Belongs to the peptidase S41A family.

1411621:AUC43 RS07900
gene id: 1411621:AUC43_RS07900
uniprot id: A0A0U4BMM9
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1411621:AUC43 RS04485
gene id: 1411621:AUC43_RS04485
uniprot id: A0A0U4CA30
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1411621:AUC43 RS07910
gene id: 1411621:AUC43_RS07910
uniprot id: A0A0U4A9Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1411621:AUC43 RS13435
gene id: 1411621:AUC43_RS13435
uniprot id: A0A0U4C4R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1411621:AUC43 RS03510
gene id: 1411621:AUC43_RS03510
uniprot id: A0A0U3SUP0
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1411621:AUC43 RS07545
gene id: 1411621:AUC43_RS07545
uniprot id: A0A0U4AW58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MerT family.
messages: Cell inner membrane
messages: Membrane

1411621:AUC43 RS05900
gene id: 1411621:AUC43_RS05900
uniprot id: A0A0U4CMZ2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1411621:AUC43 RS01320
gene id: 1411621:AUC43_RS01320
uniprot id: A0A0U3SCG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1411621:AUC43 RS00225
gene id: 1411621:AUC43_RS00225
uniprot id: A0A0U3SSZ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1411621:AUC43 RS16520
gene id: 1411621:AUC43_RS16520
uniprot id: A0A0U3K1V2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1411621:AUC43 RS10115
gene id: 1411621:AUC43_RS10115
uniprot id: A0A0U4CB48
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS01405
gene id: 1411621:AUC43_RS01405
uniprot id: A0A0U4AK63
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1411621:AUC43 RS10125
gene id: 1411621:AUC43_RS10125
uniprot id: A0A0U4BFT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1411621:AUC43 RS17310
gene id: 1411621:AUC43_RS17310
uniprot id: A0A0U4CEV2
names: Similarity
messages: Belongs to the creatininase superfamily.

1411621:AUC43 RS05485
gene id: 1411621:AUC43_RS05485
uniprot id: A0A0U4C354
names: Similarity
messages: Belongs to the SusD family.

1411621:AUC43 RS19445
gene id: 1411621:AUC43_RS19445
uniprot id: A0A0U4BKF4
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1411621:AUC43 RS04800
gene id: 1411621:AUC43_RS04800
uniprot id: A0A0U4BD06
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1411621:AUC43 RS04625
gene id: 1411621:AUC43_RS04625
uniprot id: A0A0U4ALF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1411621:AUC43 RS10465
gene id: 1411621:AUC43_RS10465
uniprot id: A0A0U4AV22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1411621:AUC43 RS17190
gene id: 1411621:AUC43_RS17190
uniprot id: A0A0U4C6S9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1411621:AUC43 RS11320
gene id: 1411621:AUC43_RS11320
uniprot id: A0A0U4CQG2
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1411621:AUC43 RS14680
gene id: 1411621:AUC43_RS14680
uniprot id: A0A0U4ADI8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1411621:AUC43 RS09505
gene id: 1411621:AUC43_RS09505
uniprot id: A0A0U4CPL0
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1411621:AUC43 RS05415
gene id: 1411621:AUC43_RS05415
uniprot id: A0A0U4AV23
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1411621:AUC43 RS04915
gene id: 1411621:AUC43_RS04915
uniprot id: A0A0U4BW46
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 3-HAO family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.

1411621:AUC43 RS10160
gene id: 1411621:AUC43_RS10160
uniprot id: A0A0U4C302
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

1411621:AUC43 RS12420
gene id: 1411621:AUC43_RS12420
uniprot id: A0A0U3SZ48
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1411621:AUC43 RS06855
gene id: 1411621:AUC43_RS06855
uniprot id: A0A0U3JW94
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1411621:AUC43 RS11495
gene id: 1411621:AUC43_RS11495
uniprot id: A0A0U4BPH4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1411621:AUC43 RS11300
gene id: 1411621:AUC43_RS11300
uniprot id: A0A0U4BGF3
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS07075
gene id: 1411621:AUC43_RS07075
uniprot id: A0A0U4BNA2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1411621:AUC43 RS05250
gene id: 1411621:AUC43_RS05250
uniprot id: A0A0U4CMP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1411621:AUC43 RS16960
gene id: 1411621:AUC43_RS16960
uniprot id: A0A0U4BSG1
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1411621:AUC43 RS13770
gene id: 1411621:AUC43_RS13770
uniprot id: A0A0U3K0J1
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1411621:AUC43 RS18345
gene id: 1411621:AUC43_RS18345
uniprot id: A0A0U4B1C9
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1411621:AUC43 RS12615
gene id: 1411621:AUC43_RS12615
uniprot id: A0A0U3SIA5
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS05050
gene id: 1411621:AUC43_RS05050
uniprot id: A0A0U4A8G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1411621:AUC43 RS14305
gene id: 1411621:AUC43_RS14305
uniprot id: A0A0U4BLC2
names: Subunit
messages: Homodimer.

1411621:AUC43 RS10425
gene id: 1411621:AUC43_RS10425
uniprot id: A0A0U4C339
names: Similarity
messages: Belongs to the SusD family.

1411621:AUC43 RS10490
gene id: 1411621:AUC43_RS10490
uniprot id: A0A0U4AXK4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1411621:AUC43 RS17380
gene id: 1411621:AUC43_RS17380
uniprot id: A0A0U3SKL5
names: Similarity
messages: Belongs to the peptidase S33 family.

1411621:AUC43 RS12750
gene id: 1411621:AUC43_RS12750
uniprot id: A0A0U3JZX0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1411621:AUC43 RS09805
gene id: 1411621:AUC43_RS09805
uniprot id: A0A0U4C2U7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS12355
gene id: 1411621:AUC43_RS12355
uniprot id: A0A0U4BQV4
names: Similarity
messages: Belongs to the peptidase U62 family.

1411621:AUC43 RS03265
gene id: 1411621:AUC43_RS03265
uniprot id: A0A0U4C202
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1411621:AUC43 RS09305
gene id: 1411621:AUC43_RS09305
uniprot id: A0A0U4BFD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1411621:AUC43 RS04555
gene id: 1411621:AUC43_RS04555
uniprot id: A0A0U4ALR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1411621:AUC43 RS01665
gene id: 1411621:AUC43_RS01665
uniprot id: A0A0U3STP5
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1411621:AUC43 RS12820
gene id: 1411621:AUC43_RS12820
uniprot id: A0A0U4AYT9
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS18570
gene id: 1411621:AUC43_RS18570
uniprot id: A0A0U4BU00
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS13955
gene id: 1411621:AUC43_RS13955
uniprot id: A0A0U4C501
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1411621:AUC43 RS16565
gene id: 1411621:AUC43_RS16565
uniprot id: A0A0U4BUX7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1411621:AUC43 RS08335
gene id: 1411621:AUC43_RS08335
uniprot id: A0A0U4C4F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1411621:AUC43 RS04490
gene id: 1411621:AUC43_RS04490
uniprot id: A0A0U4A879
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS03580
gene id: 1411621:AUC43_RS03580
uniprot id: A0A0U4BVG3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS15510
gene id: 1411621:AUC43_RS15510
uniprot id: A0A0U4AUY1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1411621:AUC43 RS10730
gene id: 1411621:AUC43_RS10730
uniprot id: A0A0U3SY87
names: Similarity
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.

1411621:AUC43 RS10070
gene id: 1411621:AUC43_RS10070
uniprot id: A0A0U4APD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1411621:AUC43 RS05625
gene id: 1411621:AUC43_RS05625
uniprot id: A0A0U4BWK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

1411621:AUC43 RS00080
gene id: 1411621:AUC43_RS00080
uniprot id: A0A0U4BIY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

1411621:AUC43 RS15970
gene id: 1411621:AUC43_RS15970
uniprot id: A0A0U4ASM7
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1411621:AUC43 RS13230
gene id: 1411621:AUC43_RS13230
uniprot id: A0A0U3K054
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1411621:AUC43 RS19485
gene id: 1411621:AUC43_RS19485
uniprot id: A0A0U3T2A2
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1411621:AUC43 RS02145
gene id: 1411621:AUC43_RS02145
uniprot id: A0A0U4BZ56
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1411621:AUC43 RS12810
gene id: 1411621:AUC43_RS12810
uniprot id: A0A0U4BH72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1411621:AUC43 RS13800
gene id: 1411621:AUC43_RS13800
uniprot id: A0A0U4AR96
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1411621:AUC43 RS14235
gene id: 1411621:AUC43_RS14235
uniprot id: A0A0U3SJ50
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1411621:AUC43 RS10720
gene id: 1411621:AUC43_RS10720
uniprot id: A0A0U4C382
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1411621:AUC43 RS14210
gene id: 1411621:AUC43_RS14210
uniprot id: A0A0U3K0R0
names: Similarity
messages: Belongs to the DprA/Smf family.

1411621:AUC43 RS00290
gene id: 1411621:AUC43_RS00290
uniprot id: A0A0U4ASA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1411621:AUC43 RS10100
gene id: 1411621:AUC43_RS10100
uniprot id: A0A0U3SGV7
names: Similarity
messages: Belongs to the glutamate synthase family.

1411621:AUC43 RS00430
gene id: 1411621:AUC43_RS00430
uniprot id: A0A0U3SC05
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1411621:AUC43 RS11475
gene id: 1411621:AUC43_RS11475
uniprot id: A0A0U3SHR2
names: Similarity
messages: Belongs to the arginase family.

1411621:AUC43 RS02375
gene id: 1411621:AUC43_RS02375
uniprot id: A0A0U4CLC6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1411621:AUC43 RS03010
gene id: 1411621:AUC43_RS03010
uniprot id: A0A0U4AG26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1411621:AUC43 RS16705
gene id: 1411621:AUC43_RS16705
uniprot id: A0A0U4CT37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1411621:AUC43 RS02205
gene id: 1411621:AUC43_RS02205
uniprot id: A0A0U4CUS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1411621:AUC43 RS01925
gene id: 1411621:AUC43_RS01925
uniprot id: A0A0U4AT79
names: Similarity
messages: Belongs to the UxaA family.

1411621:AUC43 RS08070
gene id: 1411621:AUC43_RS08070
uniprot id: A0A0U4BMR2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1411621:AUC43 RS01560
gene id: 1411621:AUC43_RS01560
uniprot id: A0A0U3JT96
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1411621:AUC43 RS05620
gene id: 1411621:AUC43_RS05620
uniprot id: A0A0U4AM12
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS16065
gene id: 1411621:AUC43_RS16065
uniprot id: A0A0U4C637
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

1411621:AUC43 RS03245
gene id: 1411621:AUC43_RS03245
uniprot id: A0A0U4AL20
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1411621:AUC43 RS08670
gene id: 1411621:AUC43_RS08670
uniprot id: A0A0U4BP05
names: Similarity
messages: Belongs to the histone deacetylase family.

1411621:AUC43 RS14020
gene id: 1411621:AUC43_RS14020
uniprot id: A0A0U4AZD1
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1411621:AUC43 RS05545
gene id: 1411621:AUC43_RS05545
uniprot id: A0A0U4C0S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1411621:AUC43 RS05305
gene id: 1411621:AUC43_RS05305
uniprot id: A0A0U4BMD8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1411621:AUC43 RS02180
gene id: 1411621:AUC43_RS02180
uniprot id: A0A0U4C701
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

1411621:AUC43 RS16000
gene id: 1411621:AUC43_RS16000
uniprot id: A0A0U3SJT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1411621:AUC43 RS03980
gene id: 1411621:AUC43_RS03980
uniprot id: A0A0U4AUT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1411621:AUC43 RS08800
gene id: 1411621:AUC43_RS08800
uniprot id: A0A0U4CP82
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1411621:AUC43 RS06610
gene id: 1411621:AUC43_RS06610
uniprot id: A0A0U4AMH5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1411621:AUC43 RS12920
gene id: 1411621:AUC43_RS12920
uniprot id: A0A0U4AYV7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1411621:AUC43 RS11235
gene id: 1411621:AUC43_RS11235
uniprot id: A0A0U3JZ41
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1411621:AUC43 RS03190
gene id: 1411621:AUC43_RS03190
uniprot id: A0A0U4BC79
names: Similarity
messages: Belongs to the creatininase superfamily.

1411621:AUC43 RS10210
gene id: 1411621:AUC43_RS10210
uniprot id: A0A0U4AB71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1411621:AUC43 RS00230
gene id: 1411621:AUC43_RS00230
uniprot id: A0A0U3SBX0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1411621:AUC43 RS17960
gene id: 1411621:AUC43_RS17960
uniprot id: A0A0U4B165
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1411621:AUC43 RS13630
gene id: 1411621:AUC43_RS13630
uniprot id: A0A0U4AR74
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS03325
gene id: 1411621:AUC43_RS03325
uniprot id: A0A0U4BZS6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1411621:AUC43 RS13450
gene id: 1411621:AUC43_RS13450
uniprot id: A0A0U4AR53
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1411621:AUC43 RS03480
gene id: 1411621:AUC43_RS03480
uniprot id: A0A0U4CLV3
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS07260
gene id: 1411621:AUC43_RS07260
uniprot id: A0A0U4C9R7
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS01270
gene id: 1411621:AUC43_RS01270
uniprot id: A0A0U4BB81
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1411621:AUC43 RS13305
gene id: 1411621:AUC43_RS13305
uniprot id: A0A0U4BQH0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1411621:AUC43 RS05255
gene id: 1411621:AUC43_RS05255
uniprot id: A0A0U3JV36
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1411621:AUC43 RS00100
gene id: 1411621:AUC43_RS00100
uniprot id: A0A0U4CK88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homotetramer.

1411621:AUC43 RS12890
gene id: 1411621:AUC43_RS12890
uniprot id: A0A0U4CCK3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1411621:AUC43 RS18280
gene id: 1411621:AUC43_RS18280
uniprot id: A0A0U4C7B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1411621:AUC43 RS08225
gene id: 1411621:AUC43_RS08225
uniprot id: A0A0U3SG01
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

1411621:AUC43 RS00670
gene id: 1411621:AUC43_RS00670
uniprot id: A0A0U4BYF2
names: Similarity
messages: Belongs to the Skp family.

1411621:AUC43 RS11920
gene id: 1411621:AUC43_RS11920
uniprot id: A0A0U4AQ92
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1411621:AUC43 RS14355
gene id: 1411621:AUC43_RS14355
uniprot id: A0A0U4BRV7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1411621:AUC43 RS07465
gene id: 1411621:AUC43_RS07465
uniprot id: A0A0U3JWL2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1411621:AUC43 RS01315
gene id: 1411621:AUC43_RS01315
uniprot id: A0A0U3STH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1411621:AUC43 RS07920
gene id: 1411621:AUC43_RS07920
uniprot id: A0A0U4CNV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1411621:AUC43 RS05505
gene id: 1411621:AUC43_RS05505
uniprot id: A0A0U4A8P3
names: Similarity
messages: Belongs to the ribulokinase family.

1411621:AUC43 RS00730
gene id: 1411621:AUC43_RS00730
uniprot id: A0A0U4ASI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1411621:AUC43 RS01735
gene id: 1411621:AUC43_RS01735
uniprot id: A0A0U4AT20
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS12500
gene id: 1411621:AUC43_RS12500
uniprot id: A0A0U4AQV6
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS11715
gene id: 1411621:AUC43_RS11715
uniprot id: A0A0U3JZC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1411621:AUC43 RS06990
gene id: 1411621:AUC43_RS06990
uniprot id: A0A0U4BN83
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1411621:AUC43 RS19750
gene id: 1411621:AUC43_RS19750
uniprot id: A0A0U4AU41
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1411621:AUC43 RS16195
gene id: 1411621:AUC43_RS16195
uniprot id: A0A0U4BIU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1411621:AUC43 RS19270
gene id: 1411621:AUC43_RS19270
uniprot id: A0A0U4C2W1
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS13270
gene id: 1411621:AUC43_RS13270
uniprot id: A0A0U3SIP8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS01365
gene id: 1411621:AUC43_RS01365
uniprot id: A0A0U4ASV7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1411621:AUC43 RS05315
gene id: 1411621:AUC43_RS05315
uniprot id: A0A0U4C8W3
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1411621:AUC43 RS06165
gene id: 1411621:AUC43_RS06165
uniprot id: A0A0U4AVG2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1411621:AUC43 RS14005
gene id: 1411621:AUC43_RS14005
uniprot id: A0A0U4BVC4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1411621:AUC43 RS13480
gene id: 1411621:AUC43_RS13480
uniprot id: A0A0U4BQK0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1411621:AUC43 RS01895
gene id: 1411621:AUC43_RS01895
uniprot id: A0A0U4C1E8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

1411621:AUC43 RS03215
gene id: 1411621:AUC43_RS03215
uniprot id: A0A0U3JU30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

1411621:AUC43 RS09590
gene id: 1411621:AUC43_RS09590
uniprot id: A0A0U4AX55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1411621:AUC43 RS10700
gene id: 1411621:AUC43_RS10700
uniprot id: A0A0U3JYV6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1411621:AUC43 RS19175
gene id: 1411621:AUC43_RS19175
uniprot id: A0A0U4ATV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XseA family.
messages: Cytoplasm

1411621:AUC43 RS13430
gene id: 1411621:AUC43_RS13430
uniprot id: A0A0U4CV92
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1411621:AUC43 RS13500
gene id: 1411621:AUC43_RS13500
uniprot id: A0A0U4AZ45
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1411621:AUC43 RS13345
gene id: 1411621:AUC43_RS13345
uniprot id: A0A0U4C4Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1411621:AUC43 RS16110
gene id: 1411621:AUC43_RS16110
uniprot id: A0A0U4BIT0
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS11465
gene id: 1411621:AUC43_RS11465
uniprot id: A0A0U3SHT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1411621:AUC43 RS12720
gene id: 1411621:AUC43_RS12720
uniprot id: A0A0U4CCI1
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS06270
gene id: 1411621:AUC43_RS06270
uniprot id: A0A0U4C136
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1411621:AUC43 RS00855
gene id: 1411621:AUC43_RS00855
uniprot id: A0A0U3T2I0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1411621:AUC43 RS10420
gene id: 1411621:AUC43_RS10420
uniprot id: A0A0U4BZ12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1411621:AUC43 RS16040
gene id: 1411621:AUC43_RS16040
uniprot id: A0A0U4B0A6
names: Similarity
messages: Belongs to the asparaginase 1 family.

1411621:AUC43 RS07580
gene id: 1411621:AUC43_RS07580
uniprot id: A0A0U3SWR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1411621:AUC43 RS15885
gene id: 1411621:AUC43_RS15885
uniprot id: A0A0U4C617
names: Similarity
messages: Belongs to the SusD family.

1411621:AUC43 RS14505
gene id: 1411621:AUC43_RS14505
uniprot id: A0A0U3T052
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1411621:AUC43 RS14990
gene id: 1411621:AUC43_RS14990
uniprot id: A0A0U4B2V3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1411621:AUC43 RS01610
gene id: 1411621:AUC43_RS01610
uniprot id: A0A0U4C1A0
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1411621:AUC43 RS01910
gene id: 1411621:AUC43_RS01910
uniprot id: A0A0U4BJT8
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1411621:AUC43 RS13410
gene id: 1411621:AUC43_RS13410
uniprot id: A0A0U4CRH2
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1411621:AUC43 RS03260
gene id: 1411621:AUC43_RS03260
uniprot id: A0A0U4AUR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1411621:AUC43 RS03675
gene id: 1411621:AUC43_RS03675
uniprot id: A0A0U3SDP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1411621:AUC43 RS12540
gene id: 1411621:AUC43_RS12540
uniprot id: A0A0U4C6B2
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1411621:AUC43 RS19005
gene id: 1411621:AUC43_RS19005
uniprot id: A0A0U4ATS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1411621:AUC43 RS10825
gene id: 1411621:AUC43_RS10825
uniprot id: A0A0U3SYA8
names: Similarity
messages: Belongs to the DapB family.

1411621:AUC43 RS01555
gene id: 1411621:AUC43_RS01555
uniprot id: A0A0U4CKX9
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1411621:AUC43 RS14540
gene id: 1411621:AUC43_RS14540
uniprot id: A0A0U4BRY5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS16490
gene id: 1411621:AUC43_RS16490
uniprot id: A0A0U4CEC7
names: Similarity
messages: Belongs to the peptidase S49 family.

1411621:AUC43 RS05005
gene id: 1411621:AUC43_RS05005
uniprot id: A0A0U3SVG5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1411621:AUC43 RS14600
gene id: 1411621:AUC43_RS14600
uniprot id: A0A0U4C102
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1411621:AUC43 RS19255
gene id: 1411621:AUC43_RS19255
uniprot id: A0A0U3K339
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1411621:AUC43 RS06005
gene id: 1411621:AUC43_RS06005
uniprot id: A0A0U4CN07
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1411621:AUC43 RS06865
gene id: 1411621:AUC43_RS06865
uniprot id: A0A0U4BX66
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1411621:AUC43 RS06150
gene id: 1411621:AUC43_RS06150
uniprot id: A0A0U4BLU3
names: Similarity
messages: Belongs to the BshC family.

1411621:AUC43 RS09725
gene id: 1411621:AUC43_RS09725
uniprot id: A0A0U3SGQ7
names: Similarity
messages: Belongs to the thioredoxin family.

1411621:AUC43 RS16895
gene id: 1411621:AUC43_RS16895
uniprot id: A0A0U4B0N2
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS07435
gene id: 1411621:AUC43_RS07435
uniprot id: A0A0U4BMF6
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1411621:AUC43 RS06895
gene id: 1411621:AUC43_RS06895
uniprot id: A0A0U3SFA0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1411621:AUC43 RS18595
gene id: 1411621:AUC43_RS18595
uniprot id: A0A0U4AFB0
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS00615
gene id: 1411621:AUC43_RS00615
uniprot id: A0A0U4C0N5
names: Similarity
messages: Belongs to the CvfB family.

1411621:AUC43 RS01920
gene id: 1411621:AUC43_RS01920
uniprot id: A0A0U4A6U1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1411621:AUC43 RS15055
gene id: 1411621:AUC43_RS15055
uniprot id: A0A0U4ADP1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1411621:AUC43 RS15820
gene id: 1411621:AUC43_RS15820
uniprot id: A0A0U4BSN9
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

1411621:AUC43 RS03465
gene id: 1411621:AUC43_RS03465
uniprot id: A0A0U4BCD0
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1411621:AUC43 RS06500
gene id: 1411621:AUC43_RS06500
uniprot id: A0A0U4BDU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1411621:AUC43 RS06630
gene id: 1411621:AUC43_RS06630
uniprot id: A0A0U3SF50
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

1411621:AUC43 RS11545
gene id: 1411621:AUC43_RS11545
uniprot id: A0A0U4BZK2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1411621:AUC43 RS06850
gene id: 1411621:AUC43_RS06850
uniprot id: A0A0U4CNE2
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1411621:AUC43 RS04980
gene id: 1411621:AUC43_RS04980
uniprot id: A0A0U4CMK5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1411621:AUC43 RS15085
gene id: 1411621:AUC43_RS15085
uniprot id: A0A0U4C151
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1411621:AUC43 RS02135
gene id: 1411621:AUC43_RS02135
uniprot id: A0A0U4AK87
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1411621:AUC43 RS01215
gene id: 1411621:AUC43_RS01215
uniprot id: A0A0U4BU91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1411621:AUC43 RS18150
gene id: 1411621:AUC43_RS18150
uniprot id: A0A0U4AF40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

1411621:AUC43 RS06010
gene id: 1411621:AUC43_RS06010
uniprot id: A0A0U3JVQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1411621:AUC43 RS09615
gene id: 1411621:AUC43_RS09615
uniprot id: A0A0U4BYK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1411621:AUC43 RS01590
gene id: 1411621:AUC43_RS01590
uniprot id: A0A0U4AK94
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS06940
gene id: 1411621:AUC43_RS06940
uniprot id: A0A0U4CNG6
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1411621:AUC43 RS17800
gene id: 1411621:AUC43_RS17800
uniprot id: A0A0U4CTL2
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1411621:AUC43 RS10450
gene id: 1411621:AUC43_RS10450
uniprot id: A0A0U4BPY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1411621:AUC43 RS13440
gene id: 1411621:AUC43_RS13440
uniprot id: A0A0U3SZP1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1411621:AUC43 RS15035
gene id: 1411621:AUC43_RS15035
uniprot id: A0A0U4CDM1
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1411621:AUC43 RS09575
gene id: 1411621:AUC43_RS09575
uniprot id: A0A0U4BFI5
names: Similarity
messages: Belongs to the HsdR family.

1411621:AUC43 RS06985
gene id: 1411621:AUC43_RS06985
uniprot id: A0A0U3SFD8
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1411621:AUC43 RS18850
gene id: 1411621:AUC43_RS18850
uniprot id: A0A0U4CFI7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1411621:AUC43 RS03315
gene id: 1411621:AUC43_RS03315
uniprot id: A0A0U4AKU3
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1411621:AUC43 RS03285
gene id: 1411621:AUC43_RS03285
uniprot id: A0A0U4A7F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1411621:AUC43 RS04835
gene id: 1411621:AUC43_RS04835
uniprot id: A0A0U4C0D6
names: Similarity
messages: Belongs to the universal stress protein A family.

1411621:AUC43 RS07150
gene id: 1411621:AUC43_RS07150
uniprot id: A0A0U3SFH6
names: Subcellular Location Annotation
messages: Cell inner membrane

1411621:AUC43 RS13340
gene id: 1411621:AUC43_RS13340
uniprot id: A0A0U4C0F4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1411621:AUC43 RS17805
gene id: 1411621:AUC43_RS17805
uniprot id: A0A0U3K2F6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1411621:AUC43 RS04860
gene id: 1411621:AUC43_RS04860
uniprot id: A0A0U4BM68
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1411621:AUC43 RS13875
gene id: 1411621:AUC43_RS13875
uniprot id: A0A0U4C4Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell.

1411621:AUC43 RS13720
gene id: 1411621:AUC43_RS13720
uniprot id: A0A0U4AR84
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1411621:AUC43 RS00190
gene id: 1411621:AUC43_RS00190
uniprot id: A0A0U4A621
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1411621:AUC43 RS15640
gene id: 1411621:AUC43_RS15640
uniprot id: A0A0U4C7Y2
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

1411621:AUC43 RS19480
gene id: 1411621:AUC43_RS19480
uniprot id: A0A0U4C7V7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1411621:AUC43 RS18875
gene id: 1411621:AUC43_RS18875
uniprot id: A0A0U4AFG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1411621:AUC43 RS14610
gene id: 1411621:AUC43_RS14610
uniprot id: A0A0U4C5A2
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1411621:AUC43 RS03635
gene id: 1411621:AUC43_RS03635
uniprot id: A0A0U4A7S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1411621:AUC43 RS17665
gene id: 1411621:AUC43_RS17665
uniprot id: A0A0U3SKL3
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1411621:AUC43 RS02920
gene id: 1411621:AUC43_RS02920
uniprot id: A0A0U4CLN1
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1411621:AUC43 RS08725
gene id: 1411621:AUC43_RS08725
uniprot id: A0A0U4ANN5
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1411621:AUC43 RS04010
gene id: 1411621:AUC43_RS04010
uniprot id: A0A0U4C8E6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1411621:AUC43 RS02880
gene id: 1411621:AUC43_RS02880
uniprot id: A0A0U3SDB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1411621:AUC43 RS14080
gene id: 1411621:AUC43_RS14080
uniprot id: A0A0U4CD21
names: Similarity
messages: Belongs to the type IB topoisomerase family.

1411621:AUC43 RS09450
gene id: 1411621:AUC43_RS09450
uniprot id: A0A0U3SXL7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

1411621:AUC43 RS10120
gene id: 1411621:AUC43_RS10120
uniprot id: A0A0U4BNQ2
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1411621:AUC43 RS18075
gene id: 1411621:AUC43_RS18075
uniprot id: A0A0U4ATN0
names: Similarity
messages: Belongs to the cytochrome P450 family.

1411621:AUC43 RS09020
gene id: 1411621:AUC43_RS09020
uniprot id: A0A0U4C4R5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1411621:AUC43 RS04755
gene id: 1411621:AUC43_RS04755
uniprot id: A0A0U3SM44
names: Similarity
messages: Belongs to the peptidase M28 family. M28B subfamily.

1411621:AUC43 RS16590
gene id: 1411621:AUC43_RS16590
uniprot id: A0A0U4CEE3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1411621:AUC43 RS03420
gene id: 1411621:AUC43_RS03420
uniprot id: A0A0U4BZT2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS15635
gene id: 1411621:AUC43_RS15635
uniprot id: A0A0U4BSJ1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1411621:AUC43 RS09900
gene id: 1411621:AUC43_RS09900
uniprot id: A0A0U4C2W0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1411621:AUC43 RS18955
gene id: 1411621:AUC43_RS18955
uniprot id: A0A0U4AFH1
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1411621:AUC43 RS04615
gene id: 1411621:AUC43_RS04615
uniprot id: A0A0U4CMF0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1411621:AUC43 RS09675
gene id: 1411621:AUC43_RS09675
uniprot id: A0A0U4BNJ8
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS02120
gene id: 1411621:AUC43_RS02120
uniprot id: A0A0U4BKS0
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1411621:AUC43 RS01675
gene id: 1411621:AUC43_RS01675
uniprot id: A0A0U4AKA9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1411621:AUC43 RS04215
gene id: 1411621:AUC43_RS04215
uniprot id: A0A0U3SM29
names: Similarity
messages: Belongs to the LOG family.

1411621:AUC43 RS05640
gene id: 1411621:AUC43_RS05640
uniprot id: A0A0U3SEN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1411621:AUC43 RS16360
gene id: 1411621:AUC43_RS16360
uniprot id: A0A0U3T0X3
names: Function
names: Similarity
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.

1411621:AUC43 RS18925
gene id: 1411621:AUC43_RS18925
uniprot id: A0A0U3SLD1
names: Similarity
messages: Belongs to the FPG family.

1411621:AUC43 RS06700
gene id: 1411621:AUC43_RS06700
uniprot id: A0A0U4AMJ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1411621:AUC43 RS00240
gene id: 1411621:AUC43_RS00240
uniprot id: A0A0U3SBY4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS04745
gene id: 1411621:AUC43_RS04745
uniprot id: A0A0U3SVB5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1411621:AUC43 RS05865
gene id: 1411621:AUC43_RS05865
uniprot id: A0A0U4C3B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1411621:AUC43 RS19550
gene id: 1411621:AUC43_RS19550
uniprot id: A0A0U4AUD6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1411621:AUC43 RS06240
gene id: 1411621:AUC43_RS06240
uniprot id: A0A0U4A948
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1411621:AUC43 RS07940
gene id: 1411621:AUC43_RS07940
uniprot id: A0A0U4C1X4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1411621:AUC43 RS10795
gene id: 1411621:AUC43_RS10795
uniprot id: A0A0U4AXP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1411621:AUC43 RS12160
gene id: 1411621:AUC43_RS12160
uniprot id: A0A0U4BZU9
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1411621:AUC43 RS13280
gene id: 1411621:AUC43_RS13280
uniprot id: A0A0U3SIL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1411621:AUC43 RS05980
gene id: 1411621:AUC43_RS05980
uniprot id: A0A0U4BDL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1411621:AUC43 RS10135
gene id: 1411621:AUC43_RS10135
uniprot id: A0A0U4AXE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1411621:AUC43 RS05260
gene id: 1411621:AUC43_RS05260
uniprot id: A0A0U4ALV1
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS10480
gene id: 1411621:AUC43_RS10480
uniprot id: A0A0U4BFY7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1411621:AUC43 RS09875
gene id: 1411621:AUC43_RS09875
uniprot id: A0A0U4AXA1
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1411621:AUC43 RS04240
gene id: 1411621:AUC43_RS04240
uniprot id: A0A0U4CM75
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1411621:AUC43 RS03425
gene id: 1411621:AUC43_RS03425
uniprot id: A0A0U3SUL6
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1411621:AUC43 RS02240
gene id: 1411621:AUC43_RS02240
uniprot id: A0A0U3STZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1411621:AUC43 RS16305
gene id: 1411621:AUC43_RS16305
uniprot id: A0A0U4BS29
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1411621:AUC43 RS04110
gene id: 1411621:AUC43_RS04110
uniprot id: A0A0U4C2G9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS07310
gene id: 1411621:AUC43_RS07310
uniprot id: A0A0U3SWK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1411621:AUC43 RS08730
gene id: 1411621:AUC43_RS08730
uniprot id: A0A0U4BY48
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS17650
gene id: 1411621:AUC43_RS17650
uniprot id: A0A0U3T1G8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1411621:AUC43 RS06910
gene id: 1411621:AUC43_RS06910
uniprot id: A0A0U4C9J8
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS12775
gene id: 1411621:AUC43_RS12775
uniprot id: A0A0U3SIG9
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1411621:AUC43 RS12710
gene id: 1411621:AUC43_RS12710
uniprot id: A0A0U4BR13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1411621:AUC43 RS17125
gene id: 1411621:AUC43_RS17125
uniprot id: A0A0U4BT97
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1411621:AUC43 RS01135
gene id: 1411621:AUC43_RS01135
uniprot id: A0A0U4BYN2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1411621:AUC43 RS02000
gene id: 1411621:AUC43_RS02000
uniprot id: A0A0U4C6W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1411621:AUC43 RS08045
gene id: 1411621:AUC43_RS08045
uniprot id: A0A0U3SFW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1411621:AUC43 RS04130
gene id: 1411621:AUC43_RS04130
uniprot id: A0A0U4A821
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1411621:AUC43 RS12480
gene id: 1411621:AUC43_RS12480
uniprot id: A0A0U4ACA6
names: Similarity
messages: Belongs to the peptidase M1 family.

1411621:AUC43 RS08460
gene id: 1411621:AUC43_RS08460
uniprot id: A0A0U4BXZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1411621:AUC43 RS03610
gene id: 1411621:AUC43_RS03610
uniprot id: A0A0U4BLJ6
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1411621:AUC43 RS04620
gene id: 1411621:AUC43_RS04620
uniprot id: A0A0U3JUT2
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS04550
gene id: 1411621:AUC43_RS04550
uniprot id: A0A0U4BKW6
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1411621:AUC43 RS10375
gene id: 1411621:AUC43_RS10375
uniprot id: A0A0U4CB98
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1411621:AUC43 RS07930
gene id: 1411621:AUC43_RS07930
uniprot id: A0A0U4AN92
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1411621:AUC43 RS07445
gene id: 1411621:AUC43_RS07445
uniprot id: A0A0U4A9S5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1411621:AUC43 RS09300
gene id: 1411621:AUC43_RS09300
uniprot id: A0A0U4BND4
names: Similarity
messages: Belongs to the SusD family.

1411621:AUC43 RS18960
gene id: 1411621:AUC43_RS18960
uniprot id: A0A0U4AV51
names: Similarity
messages: Belongs to the histone deacetylase family.

1411621:AUC43 RS05115
gene id: 1411621:AUC43_RS05115
uniprot id: A0A0U4C8S7
names: Similarity
messages: Belongs to the peptidase M13 family.

1411621:AUC43 RS05160
gene id: 1411621:AUC43_RS05160
uniprot id: A0A0U4ALS8
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1411621:AUC43 RS16800
gene id: 1411621:AUC43_RS16800
uniprot id: A0A0U4ASZ8
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1411621:AUC43 RS10990
gene id: 1411621:AUC43_RS10990
uniprot id: A0A0U4C3E2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

1411621:AUC43 RS02540
gene id: 1411621:AUC43_RS02540
uniprot id: A0A0U4C759
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1411621:AUC43 RS05845
gene id: 1411621:AUC43_RS05845
uniprot id: A0A0U4AMC7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1411621:AUC43 RS01285
gene id: 1411621:AUC43_RS01285
uniprot id: A0A0U4CKU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

1411621:AUC43 RS02340
gene id: 1411621:AUC43_RS02340
uniprot id: A0A0U4BKV6
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS04810
gene id: 1411621:AUC43_RS04810
uniprot id: A0A0U4AUS1
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1411621:AUC43 RS10745
gene id: 1411621:AUC43_RS10745
uniprot id: A0A0U3SHA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1411621:AUC43 RS07360
gene id: 1411621:AUC43_RS07360
uniprot id: A0A0U4BEB1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1411621:AUC43 RS14130
gene id: 1411621:AUC43_RS14130
uniprot id: A0A0U4C536
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1411621:AUC43 RS19625
gene id: 1411621:AUC43_RS19625
uniprot id: A0A0U3K397
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1411621:AUC43 RS06425
gene id: 1411621:AUC43_RS06425
uniprot id: A0A0U3JVX6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1411621:AUC43 RS10130
gene id: 1411621:AUC43_RS10130
uniprot id: A0A0U4AB51
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.

1411621:AUC43 RS10000
gene id: 1411621:AUC43_RS10000
uniprot id: A0A0U4APC6
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1411621:AUC43 RS08050
gene id: 1411621:AUC43_RS08050
uniprot id: A0A0U4BL19
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1411621:AUC43 RS05390
gene id: 1411621:AUC43_RS05390
uniprot id: A0A0U4C349
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1411621:AUC43 RS07840
gene id: 1411621:AUC43_RS07840
uniprot id: A0A0U3SWU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1411621:AUC43 RS15415
gene id: 1411621:AUC43_RS15415
uniprot id: A0A0U3K1A9
names: Similarity
messages: Belongs to the peptidase S24 family.

1411621:AUC43 RS14980
gene id: 1411621:AUC43_RS14980
uniprot id: A0A0U4AS38
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1411621:AUC43 RS08135
gene id: 1411621:AUC43_RS08135
uniprot id: A0A0U3SFX7
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1411621:AUC43 RS19320
gene id: 1411621:AUC43_RS19320
uniprot id: A0A0U4B330
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1411621:AUC43 RS14570
gene id: 1411621:AUC43_RS14570
uniprot id: A0A0U4AZL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1411621:AUC43 RS10005
gene id: 1411621:AUC43_RS10005
uniprot id: A0A0U3SGU4
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1411621:AUC43 RS08065
gene id: 1411621:AUC43_RS08065
uniprot id: A0A0U4CA38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1411621:AUC43 RS07850
gene id: 1411621:AUC43_RS07850
uniprot id: A0A0U4ANA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1411621:AUC43 RS18460
gene id: 1411621:AUC43_RS18460
uniprot id: A0A0U4C7E5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1411621:AUC43 RS09595
gene id: 1411621:AUC43_RS09595
uniprot id: A0A0U4CPM7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1411621:AUC43 RS00760
gene id: 1411621:AUC43_RS00760
uniprot id: A0A0U3ST87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1411621:AUC43 RS06650
gene id: 1411621:AUC43_RS06650
uniprot id: A0A0U4BN17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1411621:AUC43 RS10155
gene id: 1411621:AUC43_RS10155
uniprot id: A0A0U4BYV9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS08105
gene id: 1411621:AUC43_RS08105
uniprot id: A0A0U4ANC6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1411621:AUC43 RS15735
gene id: 1411621:AUC43_RS15735
uniprot id: A0A0U3SJQ0
names: Subcellular Location Annotation
messages: Cytoplasm

1411621:AUC43 RS10540
gene id: 1411621:AUC43_RS10540
uniprot id: A0A0U3SY54
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1411621:AUC43 RS14550
gene id: 1411621:AUC43_RS14550
uniprot id: A0A0U4CDA0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS10335
gene id: 1411621:AUC43_RS10335
uniprot id: A0A0U4BYZ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1411621:AUC43 RS02855
gene id: 1411621:AUC43_RS02855
uniprot id: A0A0U4BV29
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1411621:AUC43 RS13425
gene id: 1411621:AUC43_RS13425
uniprot id: A0A0U4C0G0
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1411621:AUC43 RS18775
gene id: 1411621:AUC43_RS18775
uniprot id: A0A0U4AFE1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS04585
gene id: 1411621:AUC43_RS04585
uniprot id: A0A0U4C8F7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1411621:AUC43 RS11210
gene id: 1411621:AUC43_RS11210
uniprot id: A0A0U4BPC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1411621:AUC43 RS12040
gene id: 1411621:AUC43_RS12040
uniprot id: A0A0U4AC43
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1411621:AUC43 RS10685
gene id: 1411621:AUC43_RS10685
uniprot id: A0A0U4ABD1
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1411621:AUC43 RS01360
gene id: 1411621:AUC43_RS01360
uniprot id: A0A0U4A6K2
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1411621:AUC43 RS06110
gene id: 1411621:AUC43_RS06110
uniprot id: A0A0U4C119
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1411621:AUC43 RS05240
gene id: 1411621:AUC43_RS05240
uniprot id: A0A0U4A8J8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1411621:AUC43 RS03300
gene id: 1411621:AUC43_RS03300
uniprot id: A0A0U4CLR7
names: Similarity
messages: Belongs to the SusD family.

1411621:AUC43 RS03705
gene id: 1411621:AUC43_RS03705
uniprot id: A0A0U4C7Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1411621:AUC43 RS06890
gene id: 1411621:AUC43_RS06890
uniprot id: A0A0U4AMU6
names: Similarity
messages: Belongs to the MoaD family.

1411621:AUC43 RS04630
gene id: 1411621:AUC43_RS04630
uniprot id: A0A0U4BW02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1411621:AUC43 RS10550
gene id: 1411621:AUC43_RS10550
uniprot id: A0A0U4APL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1411621:AUC43 RS19390
gene id: 1411621:AUC43_RS19390
uniprot id: A0A0U4C2Y1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1411621:AUC43 RS11565
gene id: 1411621:AUC43_RS11565
uniprot id: A0A0U3SHV0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1411621:AUC43 RS00630
gene id: 1411621:AUC43_RS00630
uniprot id: A0A0U4BAX3
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS06310
gene id: 1411621:AUC43_RS06310
uniprot id: A0A0U4BLW8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS14660
gene id: 1411621:AUC43_RS14660
uniprot id: A0A0U4CDB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1411621:AUC43 RS08005
gene id: 1411621:AUC43_RS08005
uniprot id: A0A0U3JWY7
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1411621:AUC43 RS01960
gene id: 1411621:AUC43_RS01960
uniprot id: A0A0U4BZ21
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1411621:AUC43 RS10870
gene id: 1411621:AUC43_RS10870
uniprot id: A0A0U4ABG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1411621:AUC43 RS11245
gene id: 1411621:AUC43_RS11245
uniprot id: A0A0U4BZF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1411621:AUC43 RS08295
gene id: 1411621:AUC43_RS08295
uniprot id: A0A0U4ANG3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1411621:AUC43 RS11750
gene id: 1411621:AUC43_RS11750
uniprot id: A0A0U4AQ65
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS04290
gene id: 1411621:AUC43_RS04290
uniprot id: A0A0U4C2J1
names: Similarity
messages: Belongs to the RutC family.

1411621:AUC43 RS05805
gene id: 1411621:AUC43_RS05805
uniprot id: A0A0U4CMX9
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1411621:AUC43 RS16910
gene id: 1411621:AUC43_RS16910
uniprot id: A0A0U4AT21
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1411621:AUC43 RS07265
gene id: 1411621:AUC43_RS07265
uniprot id: A0A0U4BMD1
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1411621:AUC43 RS06260
gene id: 1411621:AUC43_RS06260
uniprot id: A0A0U4AMB0
names: Subunit
messages: Monomer.

1411621:AUC43 RS09910
gene id: 1411621:AUC43_RS09910
uniprot id: A0A0U3SGT7
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS07985
gene id: 1411621:AUC43_RS07985
uniprot id: A0A0U4BEM9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1411621:AUC43 RS13995
gene id: 1411621:AUC43_RS13995
uniprot id: A0A0U4CD05
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1411621:AUC43 RS05400
gene id: 1411621:AUC43_RS05400
uniprot id: A0A0U4BLH2
names: Similarity
messages: Belongs to the peptidase S66 family.

1411621:AUC43 RS01210
gene id: 1411621:AUC43_RS01210
uniprot id: A0A0U4AJT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Membrane

1411621:AUC43 RS19020
gene id: 1411621:AUC43_RS19020
uniprot id: A0A0U4BU73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1411621:AUC43 RS13220
gene id: 1411621:AUC43_RS13220
uniprot id: A0A0U4AYZ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS06365
gene id: 1411621:AUC43_RS06365
uniprot id: A0A0U3SW58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1411621:AUC43 RS16050
gene id: 1411621:AUC43_RS16050
uniprot id: A0A0U3K1L4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1411621:AUC43 RS13175
gene id: 1411621:AUC43_RS13175
uniprot id: A0A0U4C6N1
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1411621:AUC43 RS06570
gene id: 1411621:AUC43_RS06570
uniprot id: A0A0U4C9G2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1411621:AUC43 RS19380
gene id: 1411621:AUC43_RS19380
uniprot id: A0A0U4AUA9
names: Similarity
messages: Belongs to the peptidase S41A family.

1411621:AUC43 RS00095
gene id: 1411621:AUC43_RS00095
uniprot id: A0A0U4AS74
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1411621:AUC43 RS19865
gene id: 1411621:AUC43_RS19865
uniprot id: A0A0U4BKM6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

1411621:AUC43 RS04305
gene id: 1411621:AUC43_RS04305
uniprot id: A0A0U4BL16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1411621:AUC43 RS16200
gene id: 1411621:AUC43_RS16200
uniprot id: A0A0U4AE98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1411621:AUC43 RS02995
gene id: 1411621:AUC43_RS02995
uniprot id: A0A0U4BKD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1411621:AUC43 RS06640
gene id: 1411621:AUC43_RS06640
uniprot id: A0A0U4CV02
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1411621:AUC43 RS08815
gene id: 1411621:AUC43_RS08815
uniprot id: A0A0U4BY63
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1411621:AUC43 RS15110
gene id: 1411621:AUC43_RS15110
uniprot id: A0A0U3SJF4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1411621:AUC43 RS19505
gene id: 1411621:AUC43_RS19505
uniprot id: A0A0U4BUF2
names: Similarity
messages: Belongs to the RNA polymerase subunit omega family.

1411621:AUC43 RS12190
gene id: 1411621:AUC43_RS12190
uniprot id: A0A0U4BQR9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1411621:AUC43 RS07990
gene id: 1411621:AUC43_RS07990
uniprot id: A0A0U4AA15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1411621:AUC43 RS05515
gene id: 1411621:AUC43_RS05515
uniprot id: A0A0U4CMS6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

1411621:AUC43 RS05105
gene id: 1411621:AUC43_RS05105
uniprot id: A0A0U4BMA8
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1411621:AUC43 RS00285
gene id: 1411621:AUC43_RS00285
uniprot id: A0A0U4A637
names: Similarity
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

1411621:AUC43 RS09895
gene id: 1411621:AUC43_RS09895
uniprot id: A0A0U4BYQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1411621:AUC43 RS19555
gene id: 1411621:AUC43_RS19555
uniprot id: A0A0U4C2Z4
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1411621:AUC43 RS03775
gene id: 1411621:AUC43_RS03775
uniprot id: A0A0U4ALB6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1411621:AUC43 RS03340
gene id: 1411621:AUC43_RS03340
uniprot id: A0A0U4AL29
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1411621:AUC43 RS07105
gene id: 1411621:AUC43_RS07105
uniprot id: A0A0U4AVY7
names: Similarity
messages: Belongs to the catalase family.

1411621:AUC43 RS11120
gene id: 1411621:AUC43_RS11120
uniprot id: A0A0U4C5P2
names: Similarity
messages: Belongs to the peptidase S9C family.

1411621:AUC43 RS04045
gene id: 1411621:AUC43_RS04045
uniprot id: A0A0U4AUD7
names: Caution
names: Function
names: Similarity
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).

1411621:AUC43 RS02245
gene id: 1411621:AUC43_RS02245
uniprot id: A0A0U3SCY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1411621:AUC43 RS10355
gene id: 1411621:AUC43_RS10355
uniprot id: A0A0U4API3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1411621:AUC43 RS00205
gene id: 1411621:AUC43_RS00205
uniprot id: A0A0U3JSM1
names: Similarity
messages: Belongs to the pyruvate kinase family.

1411621:AUC43 RS10045
gene id: 1411621:AUC43_RS10045
uniprot id: A0A0U4AXD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1411621:AUC43 RS16425
gene id: 1411621:AUC43_RS16425
uniprot id: A0A0U3K1T6
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS11590
gene id: 1411621:AUC43_RS11590
uniprot id: A0A0U4CC16
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1411621:AUC43 RS13885
gene id: 1411621:AUC43_RS13885
uniprot id: A0A0U3SIZ2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1411621:AUC43 RS00220
gene id: 1411621:AUC43_RS00220
uniprot id: A0A0U4BY82
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1411621:AUC43 RS06430
gene id: 1411621:AUC43_RS06430
uniprot id: A0A0U4AMD9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1411621:AUC43 RS07470
gene id: 1411621:AUC43_RS07470
uniprot id: A0A0U4AN16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1411621:AUC43 RS09370
gene id: 1411621:AUC43_RS09370
uniprot id: A0A0U3SGJ7
names: Similarity
messages: Belongs to the SusD family.

1411621:AUC43 RS01550
gene id: 1411621:AUC43_RS01550
uniprot id: A0A0U4C377
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1411621:AUC43 RS10660
gene id: 1411621:AUC43_RS10660
uniprot id: A0A0U4C5H1
names: Similarity
messages: Belongs to the SusD family.

1411621:AUC43 RS03370
gene id: 1411621:AUC43_RS03370
uniprot id: A0A0U4BKJ6
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1411621:AUC43 RS03760
gene id: 1411621:AUC43_RS03760
uniprot id: A0A0U4BZY3
names: Similarity
messages: Belongs to the UPF0102 family.

1411621:AUC43 RS00340
gene id: 1411621:AUC43_RS00340
uniprot id: A0A0U4AJP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1411621:AUC43 RS10740
gene id: 1411621:AUC43_RS10740
uniprot id: A0A0U4APP4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1411621:AUC43 RS11315
gene id: 1411621:AUC43_RS11315
uniprot id: A0A0U4AY04
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1411621:AUC43 RS11955
gene id: 1411621:AUC43_RS11955
uniprot id: A0A0U4AC26
names: Subcellular Location Annotation
messages: Nucleus

1411621:AUC43 RS17775
gene id: 1411621:AUC43_RS17775
uniprot id: A0A0U4BSY2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1411621:AUC43 RS11340
gene id: 1411621:AUC43_RS11340
uniprot id: A0A0U4C3M1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1411621:AUC43 RS16230
gene id: 1411621:AUC43_RS16230
uniprot id: A0A0U4C1M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1411621:AUC43 RS06315
gene id: 1411621:AUC43_RS06315
uniprot id: A0A0U4BDR7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1411621:AUC43 RS14655
gene id: 1411621:AUC43_RS14655
uniprot id: A0A0U4C7A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1411621:AUC43 RS13675
gene id: 1411621:AUC43_RS13675
uniprot id: A0A0U4AZ78
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

1411621:AUC43 RS14125
gene id: 1411621:AUC43_RS14125
uniprot id: A0A0U4C0T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1411621:AUC43 RS05885
gene id: 1411621:AUC43_RS05885
uniprot id: A0A0U4A8U2
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

1411621:AUC43 RS00015
gene id: 1411621:AUC43_RS00015
uniprot id: A0A0U4BY45
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1411621:AUC43 RS08700
gene id: 1411621:AUC43_RS08700
uniprot id: A0A0U4AAI8
names: Subcellular Location Annotation
messages: Cell inner membrane

1411621:AUC43 RS13260
gene id: 1411621:AUC43_RS13260
uniprot id: A0A0U3SZL1
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1411621:AUC43 RS12360
gene id: 1411621:AUC43_RS12360
uniprot id: A0A0U4C687
names: Similarity
messages: Belongs to the peptidase U62 family.

1411621:AUC43 RS07210
gene id: 1411621:AUC43_RS07210
uniprot id: A0A0U4BXD1
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1411621:AUC43 RS11345
gene id: 1411621:AUC43_RS11345
uniprot id: A0A0U3SYL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Cytoplasm

1411621:AUC43 RS04210
gene id: 1411621:AUC43_RS04210
uniprot id: A0A0U4BKZ9
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1411621:AUC43 RS00180
gene id: 1411621:AUC43_RS00180
uniprot id: A0A0U4BJ01
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS00740
gene id: 1411621:AUC43_RS00740
uniprot id: A0A0U3JSW1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1411621:AUC43 RS04390
gene id: 1411621:AUC43_RS04390
uniprot id: A0A0U4BL26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1411621:AUC43 RS05055
gene id: 1411621:AUC43_RS05055
uniprot id: A0A0U4AUV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1411621:AUC43 RS14915
gene id: 1411621:AUC43_RS14915
uniprot id: A0A0U4ARQ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1411621:AUC43 RS05490
gene id: 1411621:AUC43_RS05490
uniprot id: A0A0U4C8Z3
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1411621:AUC43 RS13095
gene id: 1411621:AUC43_RS13095
uniprot id: A0A0U4AYY8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1411621:AUC43 RS19540
gene id: 1411621:AUC43_RS19540
uniprot id: A0A0U4CUF5
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS01825
gene id: 1411621:AUC43_RS01825
uniprot id: A0A0U4BBH7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1411621:AUC43 RS08240
gene id: 1411621:AUC43_RS08240
uniprot id: A0A0U3SFZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1411621:AUC43 RS05195
gene id: 1411621:AUC43_RS05195
uniprot id: A0A0U4AM23
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS14250
gene id: 1411621:AUC43_RS14250
uniprot id: A0A0U4BRU5
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1411621:AUC43 RS11555
gene id: 1411621:AUC43_RS11555
uniprot id: A0A0U3SYP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1411621:AUC43 RS15080
gene id: 1411621:AUC43_RS15080
uniprot id: A0A0U4AS53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1411621:AUC43 RS07070
gene id: 1411621:AUC43_RS07070
uniprot id: A0A0U3SFF8
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1411621:AUC43 RS13400
gene id: 1411621:AUC43_RS13400
uniprot id: A0A0U4ACV8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1411621:AUC43 RS08830
gene id: 1411621:AUC43_RS08830
uniprot id: A0A0U4AUM4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS05220
gene id: 1411621:AUC43_RS05220
uniprot id: A0A0U4BLE2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

1411621:AUC43 RS16980
gene id: 1411621:AUC43_RS16980
uniprot id: A0A0U4B0Q2
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

1411621:AUC43 RS07965
gene id: 1411621:AUC43_RS07965
uniprot id: A0A0U4BNQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1411621:AUC43 RS03570
gene id: 1411621:AUC43_RS03570
uniprot id: A0A0U3JUA2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1411621:AUC43 RS14765
gene id: 1411621:AUC43_RS14765
uniprot id: A0A0U4ADK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1411621:AUC43 RS08595
gene id: 1411621:AUC43_RS08595
uniprot id: A0A0U4CAC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1411621:AUC43 RS02300
gene id: 1411621:AUC43_RS02300
uniprot id: A0A0U3JTM3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1411621:AUC43 RS11790
gene id: 1411621:AUC43_RS11790
uniprot id: A0A0U4AC00
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1411621:AUC43 RS06040
gene id: 1411621:AUC43_RS06040
uniprot id: A0A0U3SEU8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS14805
gene id: 1411621:AUC43_RS14805
uniprot id: A0A0U3T090
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1411621:AUC43 RS04370
gene id: 1411621:AUC43_RS04370
uniprot id: A0A0U3SE38
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1411621:AUC43 RS00355
gene id: 1411621:AUC43_RS00355
uniprot id: A0A0U4C0J4
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1411621:AUC43 RS11885
gene id: 1411621:AUC43_RS11885
uniprot id: A0A0U3JZF0
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS07865
gene id: 1411621:AUC43_RS07865
uniprot id: A0A0U4BNP6
names: Similarity
messages: Belongs to the peptidase M1 family.

1411621:AUC43 RS12350
gene id: 1411621:AUC43_RS12350
uniprot id: A0A0U3SI63
names: Similarity
messages: Belongs to the peptidase U62 family.

1411621:AUC43 RS01335
gene id: 1411621:AUC43_RS01335
uniprot id: A0A0U4BKB3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1411621:AUC43 RS18250
gene id: 1411621:AUC43_RS18250
uniprot id: A0A0U4CGZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1411621:AUC43 RS18870
gene id: 1411621:AUC43_RS18870
uniprot id: A0A0U4BK60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1411621:AUC43 RS14225
gene id: 1411621:AUC43_RS14225
uniprot id: A0A0U4C550
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1411621:AUC43 RS12645
gene id: 1411621:AUC43_RS12645
uniprot id: A0A0U4BH41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1411621:AUC43 RS02930
gene id: 1411621:AUC43_RS02930
uniprot id: A0A0U4AKM6
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1411621:AUC43 RS08880
gene id: 1411621:AUC43_RS08880
uniprot id: A0A0U4AWS1
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1411621:AUC43 RS14445
gene id: 1411621:AUC43_RS14445
uniprot id: A0A0U4C775
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1411621:AUC43 RS08095
gene id: 1411621:AUC43_RS08095
uniprot id: A0A0U3JX24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1411621:AUC43 RS04350
gene id: 1411621:AUC43_RS04350
uniprot id: A0A0U4C074
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1411621:AUC43 RS08035
gene id: 1411621:AUC43_RS08035
uniprot id: A0A0U3SFW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1411621:AUC43 RS01450
gene id: 1411621:AUC43_RS01450
uniprot id: A0A0U4ASX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

1411621:AUC43 RS03985
gene id: 1411621:AUC43_RS03985
uniprot id: A0A0U4C3C6
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1411621:AUC43 RS02665
gene id: 1411621:AUC43_RS02665
uniprot id: A0A0U4AKI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1411621:AUC43 RS08625
gene id: 1411621:AUC43_RS08625
uniprot id: A0A0U3JXH6
names: Similarity
messages: Belongs to the peptidase C56 family.

1411621:AUC43 RS08110
gene id: 1411621:AUC43_RS08110
uniprot id: A0A0U4BXU1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1411621:AUC43 RS18880
gene id: 1411621:AUC43_RS18880
uniprot id: A0A0U4B1M6
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS19215
gene id: 1411621:AUC43_RS19215
uniprot id: A0A0U4BTQ0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1411621:AUC43 RS14615
gene id: 1411621:AUC43_RS14615
uniprot id: A0A0U3T060
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1411621:AUC43 RS05015
gene id: 1411621:AUC43_RS05015
uniprot id: A0A0U4ALZ0
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1411621:AUC43 RS15990
gene id: 1411621:AUC43_RS15990
uniprot id: A0A0U3SJZ0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1411621:AUC43 RS01220
gene id: 1411621:AUC43_RS01220
uniprot id: A0A0U4BKQ6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1411621:AUC43 RS13515
gene id: 1411621:AUC43_RS13515
uniprot id: A0A0U4ARE1
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

1411621:AUC43 RS00035
gene id: 1411621:AUC43_RS00035
uniprot id: A0A0U4AJJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1411621:AUC43 RS13960
gene id: 1411621:AUC43_RS13960
uniprot id: A0A0U3SZX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1411621:AUC43 RS00270
gene id: 1411621:AUC43_RS00270
uniprot id: A0A0U4C647
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1411621:AUC43 RS10075
gene id: 1411621:AUC43_RS10075
uniprot id: A0A0U4BYU2
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS14950
gene id: 1411621:AUC43_RS14950
uniprot id: A0A0U4BRB1
names: Similarity
messages: Belongs to the glutamine synthetase family.

1411621:AUC43 RS02825
gene id: 1411621:AUC43_RS02825
uniprot id: A0A0U4A786
names: Subcellular Location Annotation
messages: Cytoplasm

1411621:AUC43 RS07955
gene id: 1411621:AUC43_RS07955
uniprot id: A0A0U4ANC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1411621:AUC43 RS15105
gene id: 1411621:AUC43_RS15105
uniprot id: A0A0U4ART3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS07055
gene id: 1411621:AUC43_RS07055
uniprot id: A0A0U3SWE7
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1411621:AUC43 RS01700
gene id: 1411621:AUC43_RS01700
uniprot id: A0A0U4BJQ6
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS14840
gene id: 1411621:AUC43_RS14840
uniprot id: A0A0U4CDI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1411621:AUC43 RS16725
gene id: 1411621:AUC43_RS16725
uniprot id: A0A0U4C6K6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1411621:AUC43 RS03680
gene id: 1411621:AUC43_RS03680
uniprot id: A0A0U4AL98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1411621:AUC43 RS01180
gene id: 1411621:AUC43_RS01180
uniprot id: A0A0U4BJH3
names: Similarity
messages: Belongs to the peptidase S9C family.

1411621:AUC43 RS13565
gene id: 1411621:AUC43_RS13565
uniprot id: A0A0U4CCU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1411621:AUC43 RS13470
gene id: 1411621:AUC43_RS13470
uniprot id: A0A0U4C6S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1411621:AUC43 RS16550
gene id: 1411621:AUC43_RS16550
uniprot id: A0A0U3T105
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1411621:AUC43 RS02115
gene id: 1411621:AUC43_RS02115
uniprot id: A0A0U3JTJ4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1411621:AUC43 RS07715
gene id: 1411621:AUC43_RS07715
uniprot id: A0A0U4CA74
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1411621:AUC43 RS06325
gene id: 1411621:AUC43_RS06325
uniprot id: A0A0U4AVJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1411621:AUC43 RS18340
gene id: 1411621:AUC43_RS18340
uniprot id: A0A0U4AF73
names: Similarity
messages: Belongs to the peptidase S24 family.

1411621:AUC43 RS02915
gene id: 1411621:AUC43_RS02915
uniprot id: A0A0U4ATQ1
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1411621:AUC43 RS16570
gene id: 1411621:AUC43_RS16570
uniprot id: A0A0U4ASI9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1411621:AUC43 RS14530
gene id: 1411621:AUC43_RS14530
uniprot id: A0A0U3SJ68
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1411621:AUC43 RS04610
gene id: 1411621:AUC43_RS04610
uniprot id: A0A0U4AUP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1411621:AUC43 RS00405
gene id: 1411621:AUC43_RS00405
uniprot id: A0A0U4BYB2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1411621:AUC43 RS16955
gene id: 1411621:AUC43_RS16955
uniprot id: A0A0U4CEP8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1411621:AUC43 RS14120
gene id: 1411621:AUC43_RS14120
uniprot id: A0A0U4ARN7
names: Similarity
messages: Belongs to the SusD family.

1411621:AUC43 RS05630
gene id: 1411621:AUC43_RS05630
uniprot id: A0A0U4C0U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1411621:AUC43 RS18915
gene id: 1411621:AUC43_RS18915
uniprot id: A0A0U3SLD7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1411621:AUC43 RS00525
gene id: 1411621:AUC43_RS00525
uniprot id: A0A0U4C0M0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1411621:AUC43 RS10895
gene id: 1411621:AUC43_RS10895
uniprot id: A0A0U4BZ96
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1411621:AUC43 RS03665
gene id: 1411621:AUC43_RS03665
uniprot id: A0A0U4BZX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1411621:AUC43 RS08210
gene id: 1411621:AUC43_RS08210
uniprot id: A0A0U4C219
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS15025
gene id: 1411621:AUC43_RS15025
uniprot id: A0A0U4BS68
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1411621:AUC43 RS07410
gene id: 1411621:AUC43_RS07410
uniprot id: A0A0U4AN33
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS04105
gene id: 1411621:AUC43_RS04105
uniprot id: A0A0U4BLU9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1411621:AUC43 RS04995
gene id: 1411621:AUC43_RS04995
uniprot id: A0A0U4BW60
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1411621:AUC43 RS05935
gene id: 1411621:AUC43_RS05935
uniprot id: A0A0U4C8H7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1411621:AUC43 RS16495
gene id: 1411621:AUC43_RS16495
uniprot id: A0A0U4BS60
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1411621:AUC43 RS10675
gene id: 1411621:AUC43_RS10675
uniprot id: A0A0U4BP32
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1411621:AUC43 RS14365
gene id: 1411621:AUC43_RS14365
uniprot id: A0A0U4CD60
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS18060
gene id: 1411621:AUC43_RS18060
uniprot id: A0A0U4CTQ9
names: Subcellular Location Annotation
messages: Mitochondrion

1411621:AUC43 RS05520
gene id: 1411621:AUC43_RS05520
uniprot id: A0A0U3JV77
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

1411621:AUC43 RS12055
gene id: 1411621:AUC43_RS12055
uniprot id: A0A0U3JZK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1411621:AUC43 RS13090
gene id: 1411621:AUC43_RS13090
uniprot id: A0A0U4ACN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

1411621:AUC43 RS03255
gene id: 1411621:AUC43_RS03255
uniprot id: A0A0U4BLC8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1411621:AUC43 RS16450
gene id: 1411621:AUC43_RS16450
uniprot id: A0A0U3T0Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1411621:AUC43 RS04655
gene id: 1411621:AUC43_RS04655
uniprot id: A0A0U3SE75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1411621:AUC43 RS18050
gene id: 1411621:AUC43_RS18050
uniprot id: A0A0U4C3Z7
names: Similarity
messages: Belongs to the SusD family.

1411621:AUC43 RS01010
gene id: 1411621:AUC43_RS01010
uniprot id: A0A0U4ASN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1411621:AUC43 RS10260
gene id: 1411621:AUC43_RS10260
uniprot id: A0A0U3SH02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1411621:AUC43 RS10370
gene id: 1411621:AUC43_RS10370
uniprot id: A0A0U4C5C5
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1411621:AUC43 RS00985
gene id: 1411621:AUC43_RS00985
uniprot id: A0A0U4C0V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

1411621:AUC43 RS01820
gene id: 1411621:AUC43_RS01820
uniprot id: A0A0U4AUA6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1411621:AUC43 RS03615
gene id: 1411621:AUC43_RS03615
uniprot id: A0A0U4C277
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1411621:AUC43 RS02195
gene id: 1411621:AUC43_RS02195
uniprot id: A0A0U4A6Y2
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1411621:AUC43 RS11330
gene id: 1411621:AUC43_RS11330
uniprot id: A0A0U4AQ16
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS10815
gene id: 1411621:AUC43_RS10815
uniprot id: A0A0U4BZ80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1411621:AUC43 RS15590
gene id: 1411621:AUC43_RS15590
uniprot id: A0A0U4CSK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

1411621:AUC43 RS07225
gene id: 1411621:AUC43_RS07225
uniprot id: A0A0U3SFH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1411621:AUC43 RS05330
gene id: 1411621:AUC43_RS05330
uniprot id: A0A0U4A8L3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1411621:AUC43 RS09420
gene id: 1411621:AUC43_RS09420
uniprot id: A0A0U4AX25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1411621:AUC43 RS19165
gene id: 1411621:AUC43_RS19165
uniprot id: A0A0U3T258
names: Similarity
messages: Belongs to the peptidase M13 family.

1411621:AUC43 RS01425
gene id: 1411621:AUC43_RS01425
uniprot id: A0A0U4C6N3
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1411621:AUC43 RS09905
gene id: 1411621:AUC43_RS09905
uniprot id: A0A0U3SXT5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1411621:AUC43 RS09925
gene id: 1411621:AUC43_RS09925
uniprot id: A0A0U4BPN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1411621:AUC43 RS14870
gene id: 1411621:AUC43_RS14870
uniprot id: A0A0U4CS87
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1411621:AUC43 RS07160
gene id: 1411621:AUC43_RS07160
uniprot id: A0A0U4C3Y0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1411621:AUC43 RS01140
gene id: 1411621:AUC43_RS01140
uniprot id: A0A0U3STE9
names: Similarity
messages: Belongs to the pirin family.

1411621:AUC43 RS07325
gene id: 1411621:AUC43_RS07325
uniprot id: A0A0U3SFK4
names: Similarity
messages: Belongs to the peptidase S41A family.

1411621:AUC43 RS17490
gene id: 1411621:AUC43_RS17490
uniprot id: A0A0U4BTF7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1411621:AUC43 RS19620
gene id: 1411621:AUC43_RS19620
uniprot id: A0A0U4CUH4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1411621:AUC43 RS02805
gene id: 1411621:AUC43_RS02805
uniprot id: A0A0U4C1S8
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1411621:AUC43 RS02875
gene id: 1411621:AUC43_RS02875
uniprot id: A0A0U4AKV5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1411621:AUC43 RS18000
gene id: 1411621:AUC43_RS18000
uniprot id: A0A0U4AT75
names: Similarity
messages: Belongs to the peptidase S24 family.

1411621:AUC43 RS06635
gene id: 1411621:AUC43_RS06635
uniprot id: A0A0U4AMP0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1411621:AUC43 RS19680
gene id: 1411621:AUC43_RS19680
uniprot id: A0A0U4BUI5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1411621:AUC43 RS14800
gene id: 1411621:AUC43_RS14800
uniprot id: A0A0U4C5D1
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1411621:AUC43 RS16900
gene id: 1411621:AUC43_RS16900
uniprot id: A0A0U4CT67
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1411621:AUC43 RS14195
gene id: 1411621:AUC43_RS14195
uniprot id: A0A0U4ADC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1411621:AUC43 RS16325
gene id: 1411621:AUC43_RS16325
uniprot id: A0A0U4CSY4
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS08000
gene id: 1411621:AUC43_RS08000
uniprot id: A0A0U4CNW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1411621:AUC43 RS19335
gene id: 1411621:AUC43_RS19335
uniprot id: A0A0U4C9K2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1411621:AUC43 RS02710
gene id: 1411621:AUC43_RS02710
uniprot id: A0A0U4BL20
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1411621:AUC43 RS02660
gene id: 1411621:AUC43_RS02660
uniprot id: A0A0U3SLZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1411621:AUC43 RS12245
gene id: 1411621:AUC43_RS12245
uniprot id: A0A0U4C431
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS01970
gene id: 1411621:AUC43_RS01970
uniprot id: A0A0U3SCU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1411621:AUC43 RS02065
gene id: 1411621:AUC43_RS02065
uniprot id: A0A0U4AKH2
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS07905
gene id: 1411621:AUC43_RS07905
uniprot id: A0A0U4BEL2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1411621:AUC43 RS07915
gene id: 1411621:AUC43_RS07915
uniprot id: A0A0U4AWC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1411621:AUC43 RS15995
gene id: 1411621:AUC43_RS15995
uniprot id: A0A0U4AS96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1411621:AUC43 RS04870
gene id: 1411621:AUC43_RS04870
uniprot id: A0A0U4C8N6
names: Function
names: Similarity
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.

1411621:AUC43 RS02200
gene id: 1411621:AUC43_RS02200
uniprot id: A0A0U4ATD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1411621:AUC43 RS13445
gene id: 1411621:AUC43_RS13445
uniprot id: A0A0U3SIS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1411621:AUC43 RS17630
gene id: 1411621:AUC43_RS17630
uniprot id: A0A0U3K2C5
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS19545
gene id: 1411621:AUC43_RS19545
uniprot id: A0A0U3K390
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS06785
gene id: 1411621:AUC43_RS06785
uniprot id: A0A0U4BX54
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1411621:AUC43 RS16235
gene id: 1411621:AUC43_RS16235
uniprot id: A0A0U4C6D1
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS00280
gene id: 1411621:AUC43_RS00280
uniprot id: A0A0U4BAQ6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1411621:AUC43 RS03130
gene id: 1411621:AUC43_RS03130
uniprot id: A0A0U4CUT8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1411621:AUC43 RS18800
gene id: 1411621:AUC43_RS18800
uniprot id: A0A0U4AU12
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1411621:AUC43 RS05095
gene id: 1411621:AUC43_RS05095
uniprot id: A0A0U4AM04
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS13935
gene id: 1411621:AUC43_RS13935
uniprot id: A0A0U4CRS0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS15095
gene id: 1411621:AUC43_RS15095
uniprot id: A0A0U3T0C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1411621:AUC43 RS13315
gene id: 1411621:AUC43_RS13315
uniprot id: A0A0U4ACV0
names: Subunit
messages: Homodimer.

1411621:AUC43 RS12345
gene id: 1411621:AUC43_RS12345
uniprot id: A0A0U4AQJ5
names: Similarity
messages: Belongs to the peptidase U62 family.

1411621:AUC43 RS13980
gene id: 1411621:AUC43_RS13980
uniprot id: A0A0U4BRP3
names: Similarity
messages: Belongs to the citrate synthase family.

1411621:AUC43 RS08025
gene id: 1411621:AUC43_RS08025
uniprot id: A0A0U4C1Y4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1411621:AUC43 RS08055
gene id: 1411621:AUC43_RS08055
uniprot id: A0A0U4BNS1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1411621:AUC43 RS07710
gene id: 1411621:AUC43_RS07710
uniprot id: A0A0U4A9W9
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1411621:AUC43 RS06030
gene id: 1411621:AUC43_RS06030
uniprot id: A0A0U4C105
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1411621:AUC43 RS09140
gene id: 1411621:AUC43_RS09140
uniprot id: A0A0U4AWW9
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1411621:AUC43 RS06540
gene id: 1411621:AUC43_RS06540
uniprot id: A0A0U3SW90
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

1411621:AUC43 RS07330
gene id: 1411621:AUC43_RS07330
uniprot id: A0A0U4BNE6
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

1411621:AUC43 RS11605
gene id: 1411621:AUC43_RS11605
uniprot id: A0A0U4ABW8
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS13330
gene id: 1411621:AUC43_RS13330
uniprot id: A0A0U3K069
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

1411621:AUC43 RS01265
gene id: 1411621:AUC43_RS01265
uniprot id: A0A0U4BJI9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1411621:AUC43 RS14385
gene id: 1411621:AUC43_RS14385
uniprot id: A0A0U4AZI5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1411621:AUC43 RS04440
gene id: 1411621:AUC43_RS04440
uniprot id: A0A0U3SE36
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1411621:AUC43 RS01945
gene id: 1411621:AUC43_RS01945
uniprot id: A0A0U3JTG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1411621:AUC43 RS11650
gene id: 1411621:AUC43_RS11650
uniprot id: A0A0U3SHW5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1411621:AUC43 RS15835
gene id: 1411621:AUC43_RS15835
uniprot id: A0A0U4BRV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1411621:AUC43 RS06795
gene id: 1411621:AUC43_RS06795
uniprot id: A0A0U3SWC1
names: Similarity
messages: Belongs to the SusD family.

1411621:AUC43 RS18085
gene id: 1411621:AUC43_RS18085
uniprot id: A0A0U4C787
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1411621:AUC43 RS04825
gene id: 1411621:AUC43_RS04825
uniprot id: A0A0U4ALL7
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS07780
gene id: 1411621:AUC43_RS07780
uniprot id: A0A0U4C475
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1411621:AUC43 RS10690
gene id: 1411621:AUC43_RS10690
uniprot id: A0A0U4AXN0
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1411621:AUC43 RS12090
gene id: 1411621:AUC43_RS12090
uniprot id: A0A0U3SI43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1411621:AUC43 RS16315
gene id: 1411621:AUC43_RS16315
uniprot id: A0A0U4AEC1
names: Similarity
messages: Belongs to the sterol desaturase family.

1411621:AUC43 RS18070
gene id: 1411621:AUC43_RS18070
uniprot id: A0A0U3K2K2
names: Similarity
messages: Belongs to the universal stress protein A family.

1411621:AUC43 RS03660
gene id: 1411621:AUC43_RS03660
uniprot id: A0A0U4BVH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1411621:AUC43 RS16215
gene id: 1411621:AUC43_RS16215
uniprot id: A0A0U4CSW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

1411621:AUC43 RS12475
gene id: 1411621:AUC43_RS12475
uniprot id: A0A0U4BH09
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1411621:AUC43 RS07130
gene id: 1411621:AUC43_RS07130
uniprot id: A0A0U4C1F9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1411621:AUC43 RS17005
gene id: 1411621:AUC43_RS17005
uniprot id: A0A0U4AT30
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

1411621:AUC43 RS07420
gene id: 1411621:AUC43_RS07420
uniprot id: A0A0U4BNG4
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS14695
gene id: 1411621:AUC43_RS14695
uniprot id: A0A0U3K0Y2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS07220
gene id: 1411621:AUC43_RS07220
uniprot id: A0A0U3SWJ2
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS12485
gene id: 1411621:AUC43_RS12485
uniprot id: A0A0U4AYK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1411621:AUC43 RS13110
gene id: 1411621:AUC43_RS13110
uniprot id: A0A0U4AR89
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1411621:AUC43 RS05265
gene id: 1411621:AUC43_RS05265
uniprot id: A0A0U4BWD1
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1411621:AUC43 RS10395
gene id: 1411621:AUC43_RS10395
uniprot id: A0A0U4AB98
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1411621:AUC43 RS05100
gene id: 1411621:AUC43_RS05100
uniprot id: A0A0U3SEF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1411621:AUC43 RS10735
gene id: 1411621:AUC43_RS10735
uniprot id: A0A0U3SHA4
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS05060
gene id: 1411621:AUC43_RS05060
uniprot id: A0A0U4CML8
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1411621:AUC43 RS00905
gene id: 1411621:AUC43_RS00905
uniprot id: A0A0U4BB24
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

1411621:AUC43 RS07320
gene id: 1411621:AUC43_RS07320
uniprot id: A0A0U4AN19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1411621:AUC43 RS03430
gene id: 1411621:AUC43_RS03430
uniprot id: A0A0U3SDK5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1411621:AUC43 RS08010
gene id: 1411621:AUC43_RS08010
uniprot id: A0A0U4ANB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1411621:AUC43 RS08770
gene id: 1411621:AUC43_RS08770
uniprot id: A0A0U4C4M6
names: Similarity
messages: Belongs to the AIR synthase family.

1411621:AUC43 RS14065
gene id: 1411621:AUC43_RS14065
uniprot id: A0A0U3SJ00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1411621:AUC43 RS04765
gene id: 1411621:AUC43_RS04765
uniprot id: A0A0U3SE82
names: Similarity
messages: Belongs to the peptidase S9C family.

1411621:AUC43 RS19870
gene id: 1411621:AUC43_RS19870
uniprot id: A0A0U4AFW7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1411621:AUC43 RS12905
gene id: 1411621:AUC43_RS12905
uniprot id: A0A0U4BH87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1411621:AUC43 RS07100
gene id: 1411621:AUC43_RS07100
uniprot id: A0A0U4A9N4
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1411621:AUC43 RS08780
gene id: 1411621:AUC43_RS08780
uniprot id: A0A0U4BN35
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1411621:AUC43 RS05020
gene id: 1411621:AUC43_RS05020
uniprot id: A0A0U3SED4
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1411621:AUC43 RS14510
gene id: 1411621:AUC43_RS14510
uniprot id: A0A0U3SJA0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1411621:AUC43 RS20885
gene id: 1411621:AUC43_RS20885
uniprot id: A0A0U4ANH0
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1411621:AUC43 RS05550
gene id: 1411621:AUC43_RS05550
uniprot id: A0A0U4B2F6
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1411621:AUC43 RS03845
gene id: 1411621:AUC43_RS03845
uniprot id: A0A0U4BVK5
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1411621:AUC43 RS06065
gene id: 1411621:AUC43_RS06065
uniprot id: A0A0U4C981
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS10820
gene id: 1411621:AUC43_RS10820
uniprot id: A0A0U4C3A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1411621:AUC43 RS13285
gene id: 1411621:AUC43_RS13285
uniprot id: A0A0U4BRC5
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1411621:AUC43 RS12375
gene id: 1411621:AUC43_RS12375
uniprot id: A0A0U4BGZ4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1411621:AUC43 RS11890
gene id: 1411621:AUC43_RS11890
uniprot id: A0A0U4AQA8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1411621:AUC43 RS10140
gene id: 1411621:AUC43_RS10140
uniprot id: A0A0U4CPU4
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1411621:AUC43 RS15850
gene id: 1411621:AUC43_RS15850
uniprot id: A0A0U4AE46
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS00310
gene id: 1411621:AUC43_RS00310
uniprot id: A0A0U4AJC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1411621:AUC43 RS16345
gene id: 1411621:AUC43_RS16345
uniprot id: A0A0U4C1P3
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1411621:AUC43 RS07140
gene id: 1411621:AUC43_RS07140
uniprot id: A0A0U3SFG2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

1411621:AUC43 RS14955
gene id: 1411621:AUC43_RS14955
uniprot id: A0A0U4BI86
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1411621:AUC43 RS07745
gene id: 1411621:AUC43_RS07745
uniprot id: A0A0U4BXM5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1411621:AUC43 RS04275
gene id: 1411621:AUC43_RS04275
uniprot id: A0A0U4ALK6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1411621:AUC43 RS18140
gene id: 1411621:AUC43_RS18140
uniprot id: A0A0U3SMP4
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1411621:AUC43 RS15495
gene id: 1411621:AUC43_RS15495
uniprot id: A0A0U4CSK0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1411621:AUC43 RS03005
gene id: 1411621:AUC43_RS03005
uniprot id: A0A0U4A7C0
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1411621:AUC43 RS00770
gene id: 1411621:AUC43_RS00770
uniprot id: A0A0U4AJW5
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1411621:AUC43 RS07885
gene id: 1411621:AUC43_RS07885
uniprot id: A0A0U4C487
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1411621:AUC43 RS03920
gene id: 1411621:AUC43_RS03920
uniprot id: A0A0U4A7X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1411621:AUC43 RS16870
gene id: 1411621:AUC43_RS16870
uniprot id: A0A0U4CEN4
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1411621:AUC43 RS00535
gene id: 1411621:AUC43_RS00535
uniprot id: A0A0U4BJ67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

1411621:AUC43 RS04525
gene id: 1411621:AUC43_RS04525
uniprot id: A0A0U4C098
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1411621:AUC43 RS00195
gene id: 1411621:AUC43_RS00195
uniprot id: A0A0U4AS89
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1411621:AUC43 RS16225
gene id: 1411621:AUC43_RS16225
uniprot id: A0A0U4ASR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1411621:AUC43 RS18615
gene id: 1411621:AUC43_RS18615
uniprot id: A0A0U3K2U4
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase 20 family.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the trehalose phosphatase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 20 family.

1411621:AUC43 RS18665
gene id: 1411621:AUC43_RS18665
uniprot id: A0A0U4CFF8
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1411621:AUC43 RS03160
gene id: 1411621:AUC43_RS03160
uniprot id: A0A0U3SDG9
names: Similarity
messages: Belongs to the pirin family.

1411621:AUC43 RS18635
gene id: 1411621:AUC43_RS18635
uniprot id: A0A0U3T1X5
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 zinc ion per subunit.

1411621:AUC43 RS01905
gene id: 1411621:AUC43_RS01905
uniprot id: A0A0U3SLY0
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS02290
gene id: 1411621:AUC43_RS02290
uniprot id: A0A0U4ATF2
names: Similarity
messages: Belongs to the Skp family.

1411621:AUC43 RS11355
gene id: 1411621:AUC43_RS11355
uniprot id: A0A0U3SHR6
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1411621:AUC43 RS12740
gene id: 1411621:AUC43_RS12740
uniprot id: A0A0U4AYS0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1411621:AUC43 RS00725
gene id: 1411621:AUC43_RS00725
uniprot id: A0A0U4A6B6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1411621:AUC43 RS07290
gene id: 1411621:AUC43_RS07290
uniprot id: A0A0U3JWI5
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS12425
gene id: 1411621:AUC43_RS12425
uniprot id: A0A0U3SIA6
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

1411621:AUC43 RS15680
gene id: 1411621:AUC43_RS15680
uniprot id: A0A0U4BVG2
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1411621:AUC43 RS02485
gene id: 1411621:AUC43_RS02485
uniprot id: A0A0U4AUP9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1411621:AUC43 RS10780
gene id: 1411621:AUC43_RS10780
uniprot id: A0A0U4BP47
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

1411621:AUC43 RS04970
gene id: 1411621:AUC43_RS04970
uniprot id: A0A0U4A8F2
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

1411621:AUC43 RS00950
gene id: 1411621:AUC43_RS00950
uniprot id: A0A0U4BYJ9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1411621:AUC43 RS08250
gene id: 1411621:AUC43_RS08250
uniprot id: A0A0U4C4E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1411621:AUC43 RS01785
gene id: 1411621:AUC43_RS01785
uniprot id: A0A0U4AKC3
names: Similarity
messages: Belongs to the DEAD box helicase family.

1411621:AUC43 RS05925
gene id: 1411621:AUC43_RS05925
uniprot id: A0A0U3SVY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1411621:AUC43 RS01950
gene id: 1411621:AUC43_RS01950
uniprot id: A0A0U4AK55
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

1411621:AUC43 RS05420
gene id: 1411621:AUC43_RS05420
uniprot id: A0A0U4BUF6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1411621:AUC43 RS15770
gene id: 1411621:AUC43_RS15770
uniprot id: A0A0U4B056
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1411621:AUC43 RS19640
gene id: 1411621:AUC43_RS19640
uniprot id: A0A0U4C305
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1411621:AUC43 RS21760
gene id: 1411621:AUC43_RS21760
uniprot id: A0A0U4BUU8
names: Similarity
messages: Belongs to the HsdR family.

1411621:AUC43 RS02510
gene id: 1411621:AUC43_RS02510
uniprot id: A0A0U4AKP9
names: Similarity
messages: Belongs to the UPF0234 family.

1411621:AUC43 RS19025
gene id: 1411621:AUC43_RS19025
uniprot id: A0A0U4C9H1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1411621:AUC43 RS13145
gene id: 1411621:AUC43_RS13145
uniprot id: A0A0U3SIN4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1411621:AUC43 RS05760
gene id: 1411621:AUC43_RS05760
uniprot id: A0A0U4AMA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1411621:AUC43 RS04590
gene id: 1411621:AUC43_RS04590
uniprot id: A0A0U4BL52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1411621:AUC43 RS07350
gene id: 1411621:AUC43_RS07350
uniprot id: A0A0U4BME5
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1411621:AUC43 RS15160
gene id: 1411621:AUC43_RS15160
uniprot id: A0A0U4CSB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1411621:AUC43 RS00245
gene id: 1411621:AUC43_RS00245
uniprot id: A0A0U4BJR4
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS05000
gene id: 1411621:AUC43_RS05000
uniprot id: A0A0U4C0I9
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1411621:AUC43 RS04395
gene id: 1411621:AUC43_RS04395
uniprot id: A0A0U4BCU5
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS09265
gene id: 1411621:AUC43_RS09265
uniprot id: A0A0U4ANY9
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

1411621:AUC43 RS03385
gene id: 1411621:AUC43_RS03385
uniprot id: A0A0U4AU17
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1411621:AUC43 RS00315
gene id: 1411621:AUC43_RS00315
uniprot id: A0A0U4BTT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1411621:AUC43 RS10545
gene id: 1411621:AUC43_RS10545
uniprot id: A0A0U3SH83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1411621:AUC43 RS06480
gene id: 1411621:AUC43_RS06480
uniprot id: A0A0U4AG92
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1411621:AUC43 RS14890
gene id: 1411621:AUC43_RS14890
uniprot id: A0A0U4C133
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1411621:AUC43 RS01540
gene id: 1411621:AUC43_RS01540
uniprot id: A0A0U4ASY7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1411621:AUC43 RS13475
gene id: 1411621:AUC43_RS13475
uniprot id: A0A0U4CCS9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1411621:AUC43 RS07970
gene id: 1411621:AUC43_RS07970
uniprot id: A0A0U4C497
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1411621:AUC43 RS02075
gene id: 1411621:AUC43_RS02075
uniprot id: A0A0U4BKQ2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1411621:AUC43 RS19710
gene id: 1411621:AUC43_RS19710
uniprot id: A0A0U4B210
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS14415
gene id: 1411621:AUC43_RS14415
uniprot id: A0A0U4C579
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1411621:AUC43 RS04435
gene id: 1411621:AUC43_RS04435
uniprot id: A0A0U3SV73
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1411621:AUC43 RS16505
gene id: 1411621:AUC43_RS16505
uniprot id: A0A0U4AEE7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1411621:AUC43 RS02445
gene id: 1411621:AUC43_RS02445
uniprot id: A0A0U4A725
names: Similarity
messages: Belongs to the peptidase S33 family.

1411621:AUC43 RS16320
gene id: 1411621:AUC43_RS16320
uniprot id: A0A0U4B0E8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1411621:AUC43 RS15620
gene id: 1411621:AUC43_RS15620
uniprot id: A0A0U3SJT0
names: Similarity
messages: Belongs to the DEAD box helicase family.

1411621:AUC43 RS13295
gene id: 1411621:AUC43_RS13295
uniprot id: A0A0U4C6P6
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1411621:AUC43 RS02315
gene id: 1411621:AUC43_RS02315
uniprot id: A0A0U4BZ92
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS01580
gene id: 1411621:AUC43_RS01580
uniprot id: A0A0U3STM9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1411621:AUC43 RS06945
gene id: 1411621:AUC43_RS06945
uniprot id: A0A0U3JWB9
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1411621:AUC43 RS03095
gene id: 1411621:AUC43_RS03095
uniprot id: A0A0U4A7D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

1411621:AUC43 RS02260
gene id: 1411621:AUC43_RS02260
uniprot id: A0A0U4BKT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

1411621:AUC43 RS07975
gene id: 1411621:AUC43_RS07975
uniprot id: A0A0U4CA22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1411621:AUC43 RS07565
gene id: 1411621:AUC43_RS07565
uniprot id: A0A0U4AN24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1411621:AUC43 RS11365
gene id: 1411621:AUC43_RS11365
uniprot id: A0A0U3K3Y9
names: Similarity
messages: Belongs to the Fur family.

1411621:AUC43 RS08475
gene id: 1411621:AUC43_RS08475
uniprot id: A0A0U3SX44
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1411621:AUC43 RS14515
gene id: 1411621:AUC43_RS14515
uniprot id: A0A0U4ARK2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS08080
gene id: 1411621:AUC43_RS08080
uniprot id: A0A0U4AA41
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1411621:AUC43 RS02955
gene id: 1411621:AUC43_RS02955
uniprot id: A0A0U3SDC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1411621:AUC43 RS19145
gene id: 1411621:AUC43_RS19145
uniprot id: A0A0U3K325
names: Similarity
messages: Belongs to the manganese catalase family.

1411621:AUC43 RS12265
gene id: 1411621:AUC43_RS12265
uniprot id: A0A0U3SI48
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS09500
gene id: 1411621:AUC43_RS09500
uniprot id: A0A0U4AX40
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1411621:AUC43 RS11440
gene id: 1411621:AUC43_RS11440
uniprot id: A0A0U3JZ73
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1411621:AUC43 RS12805
gene id: 1411621:AUC43_RS12805
uniprot id: A0A0U4BQ72
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1411621:AUC43 RS19850
gene id: 1411621:AUC43_RS19850
uniprot id: A0A0U4C9T9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1411621:AUC43 RS10525
gene id: 1411621:AUC43_RS10525
uniprot id: A0A0U4C356
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1411621:AUC43 RS11460
gene id: 1411621:AUC43_RS11460
uniprot id: A0A0U3SYM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1411621:AUC43 RS00555
gene id: 1411621:AUC43_RS00555
uniprot id: A0A0U4ASF6
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1411621:AUC43 RS06475
gene id: 1411621:AUC43_RS06475
uniprot id: A0A0U4BMY7
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS19345
gene id: 1411621:AUC43_RS19345
uniprot id: A0A0U4BTR5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1411621:AUC43 RS01985
gene id: 1411621:AUC43_RS01985
uniprot id: A0A0U3SCW2
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

1411621:AUC43 RS13840
gene id: 1411621:AUC43_RS13840
uniprot id: A0A0U4AD19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1411621:AUC43 RS07980
gene id: 1411621:AUC43_RS07980
uniprot id: A0A0U4BMP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1411621:AUC43 RS03105
gene id: 1411621:AUC43_RS03105
uniprot id: A0A0U4CLQ4
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1411621:AUC43 RS05445
gene id: 1411621:AUC43_RS05445
uniprot id: A0A0U4ALX1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1411621:AUC43 RS09890
gene id: 1411621:AUC43_RS09890
uniprot id: A0A0U4AP96
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1411621:AUC43 RS08040
gene id: 1411621:AUC43_RS08040
uniprot id: A0A0U4AND8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1411621:AUC43 RS02280
gene id: 1411621:AUC43_RS02280
uniprot id: A0A0U4BBS4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1411621:AUC43 RS12285
gene id: 1411621:AUC43_RS12285
uniprot id: A0A0U4CCA9
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1411621:AUC43 RS14565
gene id: 1411621:AUC43_RS14565
uniprot id: A0A0U4ADH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1411621:AUC43 RS08755
gene id: 1411621:AUC43_RS08755
uniprot id: A0A0U4ANR0
names: Similarity
messages: Belongs to the GARS family.

1411621:AUC43 RS08735
gene id: 1411621:AUC43_RS08735
uniprot id: A0A0U4C2B4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1411621:AUC43 RS11280
gene id: 1411621:AUC43_RS11280
uniprot id: A0A0U4C5S4
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS19110
gene id: 1411621:AUC43_RS19110
uniprot id: A0A0U4C9I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1411621:AUC43 RS14380
gene id: 1411621:AUC43_RS14380
uniprot id: A0A0U4ADF0
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1411621:AUC43 RS13375
gene id: 1411621:AUC43_RS13375
uniprot id: A0A0U4BRD9
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1411621:AUC43 RS05205
gene id: 1411621:AUC43_RS05205
uniprot id: A0A0U4BMC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1411621:AUC43 RS03655
gene id: 1411621:AUC43_RS03655
uniprot id: A0A0U4AL04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1411621:AUC43 RS00480
gene id: 1411621:AUC43_RS00480
uniprot id: A0A0U3JSR7
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1411621:AUC43 RS03445
gene id: 1411621:AUC43_RS03445
uniprot id: A0A0U4BLG3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1411621:AUC43 RS16915
gene id: 1411621:AUC43_RS16915
uniprot id: A0A0U4C1W1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

1411621:AUC43 RS16220
gene id: 1411621:AUC43_RS16220
uniprot id: A0A0U3K1P5
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS14440
gene id: 1411621:AUC43_RS14440
uniprot id: A0A0U4BRX2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

1411621:AUC43 RS06975
gene id: 1411621:AUC43_RS06975
uniprot id: A0A0U3SFC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1411621:AUC43 RS14015
gene id: 1411621:AUC43_RS14015
uniprot id: A0A0U4AD44
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1411621:AUC43 RS01570
gene id: 1411621:AUC43_RS01570
uniprot id: A0A0U4BUF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1411621:AUC43 RS02150
gene id: 1411621:AUC43_RS02150
uniprot id: A0A0U3STX4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1411621:AUC43 RS09480
gene id: 1411621:AUC43_RS09480
uniprot id: A0A0U4CAW2
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1411621:AUC43 RS00215
gene id: 1411621:AUC43_RS00215
uniprot id: A0A0U4BTR7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1411621:AUC43 RS01620
gene id: 1411621:AUC43_RS01620
uniprot id: A0A0U4BJP9
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS10385
gene id: 1411621:AUC43_RS10385
uniprot id: A0A0U4BNY0
names: Similarity
messages: Belongs to the ComB family.

1411621:AUC43 RS01870
gene id: 1411621:AUC43_RS01870
uniprot id: A0A0U3STS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1411621:AUC43 RS01575
gene id: 1411621:AUC43_RS01575
uniprot id: A0A0U4BYW8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1411621:AUC43 RS19575
gene id: 1411621:AUC43_RS19575
uniprot id: A0A0U4AU10
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1411621:AUC43 RS11230
gene id: 1411621:AUC43_RS11230
uniprot id: A0A0U4CQB2
names: Similarity
messages: Belongs to the SusD family.

1411621:AUC43 RS12895
gene id: 1411621:AUC43_RS12895
uniprot id: A0A0U4C8Q7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1411621:AUC43 RS07945
gene id: 1411621:AUC43_RS07945
uniprot id: A0A0U3SWV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1411621:AUC43 RS09490
gene id: 1411621:AUC43_RS09490
uniprot id: A0A0U4BFG6
names: Similarity
messages: Belongs to the SusD family.

1411621:AUC43 RS08285
gene id: 1411621:AUC43_RS08285
uniprot id: A0A0U4CNY9
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

1411621:AUC43 RS14835
gene id: 1411621:AUC43_RS14835
uniprot id: A0A0U4C7D3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1411621:AUC43 RS10555
gene id: 1411621:AUC43_RS10555
uniprot id: A0A0U3SH55
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS19520
gene id: 1411621:AUC43_RS19520
uniprot id: A0A0U4BTV2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1411621:AUC43 RS17200
gene id: 1411621:AUC43_RS17200
uniprot id: A0A0U3SKI1
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1411621:AUC43 RS10205
gene id: 1411621:AUC43_RS10205
uniprot id: A0A0U4BFU5
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1411621:AUC43 RS04770
gene id: 1411621:AUC43_RS04770
uniprot id: A0A0U4ALV3
names: Similarity
messages: Belongs to the peptidase S33 family.

1411621:AUC43 RS07315
gene id: 1411621:AUC43_RS07315
uniprot id: A0A0U3SFJ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1411621:AUC43 RS14665
gene id: 1411621:AUC43_RS14665
uniprot id: A0A0U4BR61
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS17135
gene id: 1411621:AUC43_RS17135
uniprot id: A0A0U4C8N7
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

1411621:AUC43 RS08085
gene id: 1411621:AUC43_RS08085
uniprot id: A0A0U4AWF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1411621:AUC43 RS06320
gene id: 1411621:AUC43_RS06320
uniprot id: A0A0U4A963
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1411621:AUC43 RS16180
gene id: 1411621:AUC43_RS16180
uniprot id: A0A0U4C875
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1411621:AUC43 RS10875
gene id: 1411621:AUC43_RS10875
uniprot id: A0A0U4AXR6
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS04400
gene id: 1411621:AUC43_RS04400
uniprot id: A0A0U4A865
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS04900
gene id: 1411621:AUC43_RS04900
uniprot id: A0A0U4CMI8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS14895
gene id: 1411621:AUC43_RS14895
uniprot id: A0A0U4C5E3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS00385
gene id: 1411621:AUC43_RS00385
uniprot id: A0A0U4CKD9
names: Similarity
messages: Belongs to the UPF0235 family.

1411621:AUC43 RS04540
gene id: 1411621:AUC43_RS04540
uniprot id: A0A0U3SE51
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1411621:AUC43 RS19820
gene id: 1411621:AUC43_RS19820
uniprot id: A0A0U3T2G0
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

1411621:AUC43 RS02350
gene id: 1411621:AUC43_RS02350
uniprot id: A0A0U4C737
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS09680
gene id: 1411621:AUC43_RS09680
uniprot id: A0A0U4BFK5
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS08345
gene id: 1411621:AUC43_RS08345
uniprot id: A0A0U4BMW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

1411621:AUC43 RS17635
gene id: 1411621:AUC43_RS17635
uniprot id: A0A0U4ATD3
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS17495
gene id: 1411621:AUC43_RS17495
uniprot id: A0A0U4C8U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Cell wall formation.
messages: Cytoplasm

1411621:AUC43 RS13240
gene id: 1411621:AUC43_RS13240
uniprot id: A0A0U4C0E5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1411621:AUC43 RS14500
gene id: 1411621:AUC43_RS14500
uniprot id: A0A0U4C592
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1411621:AUC43 RS00165
gene id: 1411621:AUC43_RS00165
uniprot id: A0A0U4C0H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1411621:AUC43 RS01355
gene id: 1411621:AUC43_RS01355
uniprot id: A0A0U4BBA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1411621:AUC43 RS03565
gene id: 1411621:AUC43_RS03565
uniprot id: A0A0U4CLW1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1411621:AUC43 RS16760
gene id: 1411621:AUC43_RS16760
uniprot id: A0A0U4C8D5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1411621:AUC43 RS01535
gene id: 1411621:AUC43_RS01535
uniprot id: A0A0U3K3H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1411621:AUC43 RS09970
gene id: 1411621:AUC43_RS09970
uniprot id: A0A0U3JYG1
names: Similarity
messages: Belongs to the TPP enzyme family.

1411621:AUC43 RS09395
gene id: 1411621:AUC43_RS09395
uniprot id: A0A0U4BNE9
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1411621:AUC43 RS19040
gene id: 1411621:AUC43_RS19040
uniprot id: A0A0U4BK91
names: Similarity
messages: Belongs to the CarB family.

1411621:AUC43 RS05370
gene id: 1411621:AUC43_RS05370
uniprot id: A0A0U3SEJ4
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS17535
gene id: 1411621:AUC43_RS17535
uniprot id: A0A0U4ATB6
names: Similarity
messages: Belongs to the peptidase S58 family.

1411621:AUC43 RS01630
gene id: 1411621:AUC43_RS01630
uniprot id: A0A0U4A6P0
names: Similarity
messages: Belongs to the NDK family.

1411621:AUC43 RS19030
gene id: 1411621:AUC43_RS19030
uniprot id: A0A0U4CFL3
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1411621:AUC43 RS00255
gene id: 1411621:AUC43_RS00255
uniprot id: A0A0U4C0I2
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1411621:AUC43 RS05915
gene id: 1411621:AUC43_RS05915
uniprot id: A0A0U4BWP4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1411621:AUC43 RS01155
gene id: 1411621:AUC43_RS01155
uniprot id: A0A0U4AK20
names: Similarity
messages: Belongs to the peptidase S9A family.

1411621:AUC43 RS16255
gene id: 1411621:AUC43_RS16255
uniprot id: A0A0U3T0W1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1411621:AUC43 RS01760
gene id: 1411621:AUC43_RS01760
uniprot id: A0A0U4BUI9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1411621:AUC43 RS08765
gene id: 1411621:AUC43_RS08765
uniprot id: A0A0U4BP20
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1411621:AUC43 RS11915
gene id: 1411621:AUC43_RS11915
uniprot id: A0A0U3SI10
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1411621:AUC43 RS06600
gene id: 1411621:AUC43_RS06600
uniprot id: A0A0U4CN95
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1411621:AUC43 RS18895
gene id: 1411621:AUC43_RS18895
uniprot id: A0A0U4AU24
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1411621:AUC43 RS08090
gene id: 1411621:AUC43_RS08090
uniprot id: A0A0U4CNX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1411621:AUC43 RS05535
gene id: 1411621:AUC43_RS05535
uniprot id: A0A0U4BWI7
names: Similarity
messages: Belongs to the glycosyl hydrolase.

1411621:AUC43 RS07215
gene id: 1411621:AUC43_RS07215
uniprot id: A0A0U4C1H8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1411621:AUC43 RS02230
gene id: 1411621:AUC43_RS02230
uniprot id: A0A0U3K3J5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1411621:AUC43 RS11960
gene id: 1411621:AUC43_RS11960
uniprot id: A0A0U4AYB3
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1411621:AUC43 RS18055
gene id: 1411621:AUC43_RS18055
uniprot id: A0A0U4B181
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1411621:AUC43 RS18240
gene id: 1411621:AUC43_RS18240
uniprot id: A0A0U4BJV6
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS11510
gene id: 1411621:AUC43_RS11510
uniprot id: A0A0U4AY40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1411621:AUC43 RS09975
gene id: 1411621:AUC43_RS09975
uniprot id: A0A0U4APB4
names: Similarity
messages: Belongs to the UPF0162 family.

1411621:AUC43 RS06140
gene id: 1411621:AUC43_RS06140
uniprot id: A0A0U4C3F6
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1411621:AUC43 RS14645
gene id: 1411621:AUC43_RS14645
uniprot id: A0A0U3SJ81
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

1411621:AUC43 RS19530
gene id: 1411621:AUC43_RS19530
uniprot id: A0A0U4AFQ7
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1411621:AUC43 RS16030
gene id: 1411621:AUC43_RS16030
uniprot id: A0A0U4AE79
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS08430
gene id: 1411621:AUC43_RS08430
uniprot id: A0A0U4BEW8
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1411621:AUC43 RS04465
gene id: 1411621:AUC43_RS04465
uniprot id: A0A0U4C8E2
names: Similarity
messages: Belongs to the peptidase C40 family.

1411621:AUC43 RS16600
gene id: 1411621:AUC43_RS16600
uniprot id: A0A0U4BJ06
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1411621:AUC43 RS03365
gene id: 1411621:AUC43_RS03365
uniprot id: A0A0U4C7S2
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1411621:AUC43 RS16650
gene id: 1411621:AUC43_RS16650
uniprot id: A0A0U4ASL2
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS14480
gene id: 1411621:AUC43_RS14480
uniprot id: A0A0U4CS22
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS06955
gene id: 1411621:AUC43_RS06955
uniprot id: A0A0U4AMN5
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS08930
gene id: 1411621:AUC43_RS08930
uniprot id: A0A0U4BP60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1411621:AUC43 RS02575
gene id: 1411621:AUC43_RS02575
uniprot id: A0A0U4AKG7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS13985
gene id: 1411621:AUC43_RS13985
uniprot id: A0A0U4C709
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1411621:AUC43 RS03890
gene id: 1411621:AUC43_RS03890
uniprot id: A0A0U4C2C8
names: Similarity
messages: Belongs to the SusD family.

1411621:AUC43 RS16775
gene id: 1411621:AUC43_RS16775
uniprot id: A0A0U4BJ26
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1411621:AUC43 RS13815
gene id: 1411621:AUC43_RS13815
uniprot id: A0A0U4C6X9
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1411621:AUC43 RS05920
gene id: 1411621:AUC43_RS05920
uniprot id: A0A0U4C0Z3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1411621:AUC43 RS18290
gene id: 1411621:AUC43_RS18290
uniprot id: A0A0U3T1S1
names: Similarity
messages: Belongs to the SUI1 family.

1411621:AUC43 RS07830
gene id: 1411621:AUC43_RS07830
uniprot id: A0A0U4BXN9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1411621:AUC43 RS07155
gene id: 1411621:AUC43_RS07155
uniprot id: A0A0U4BNB4
names: Similarity
messages: Belongs to the sigma-54 factor family.

1411621:AUC43 RS07845
gene id: 1411621:AUC43_RS07845
uniprot id: A0A0U3SFT3
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1411621:AUC43 RS18245
gene id: 1411621:AUC43_RS18245
uniprot id: A0A0U4AF52
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

1411621:AUC43 RS07455
gene id: 1411621:AUC43_RS07455
uniprot id: A0A0U4CNP4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1411621:AUC43 RS16285
gene id: 1411621:AUC43_RS16285
uniprot id: A0A0U4BSU6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1411621:AUC43 RS02170
gene id: 1411621:AUC43_RS02170
uniprot id: A0A0U4BKS3
names: Similarity
messages: Belongs to the arginase family.

1411621:AUC43 RS14685
gene id: 1411621:AUC43_RS14685
uniprot id: A0A0U4AZN0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1411621:AUC43 RS11450
gene id: 1411621:AUC43_RS11450
uniprot id: A0A0U4BZI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1411621:AUC43 RS18785
gene id: 1411621:AUC43_RS18785
uniprot id: A0A0U4C412
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1411621:AUC43 RS12370
gene id: 1411621:AUC43_RS12370
uniprot id: A0A0U4BPZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1411621:AUC43 RS06070
gene id: 1411621:AUC43_RS06070
uniprot id: A0A0U4BLS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1411621:AUC43 RS08525
gene id: 1411621:AUC43_RS08525
uniprot id: A0A0U4AAB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

1411621:AUC43 RS19045
gene id: 1411621:AUC43_RS19045
uniprot id: A0A0U4AFI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.
messages: Homotrimer.

1411621:AUC43 RS10410
gene id: 1411621:AUC43_RS10410
uniprot id: A0A0U3JYQ4
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1411621:AUC43 RS07400
gene id: 1411621:AUC43_RS07400
uniprot id: A0A0U3SWM5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1411621:AUC43 RS12340
gene id: 1411621:AUC43_RS12340
uniprot id: A0A0U3SI89
names: Similarity
messages: Belongs to the peptidase U62 family.

1411621:AUC43 RS19880
gene id: 1411621:AUC43_RS19880
uniprot id: A0A0U4CUN2
names: Similarity
messages: Belongs to the asparagine synthetase family.

1411621:AUC43 RS06505
gene id: 1411621:AUC43_RS06505
uniprot id: A0A0U4A994
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1411621:AUC43 RS12655
gene id: 1411621:AUC43_RS12655
uniprot id: A0A0U4ACD3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1411621:AUC43 RS10645
gene id: 1411621:AUC43_RS10645
uniprot id: A0A0U4APM7
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

1411621:AUC43 RS17695
gene id: 1411621:AUC43_RS17695
uniprot id: A0A0U4BJI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1411621:AUC43 RS14495
gene id: 1411621:AUC43_RS14495
uniprot id: A0A0U4C0Z7
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1411621:AUC43 RS19250
gene id: 1411621:AUC43_RS19250
uniprot id: A0A0U4CUA8
names: Similarity
messages: Belongs to the SusD family.

1411621:AUC43 RS10710
gene id: 1411621:AUC43_RS10710
uniprot id: A0A0U4BZ55
names: Similarity
messages: Belongs to the ribF family.

1411621:AUC43 RS18475
gene id: 1411621:AUC43_RS18475
uniprot id: A0A0U4ATF0
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS06715
gene id: 1411621:AUC43_RS06715
uniprot id: A0A0U3SWB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1411621:AUC43 RS16985
gene id: 1411621:AUC43_RS16985
uniprot id: A0A0U4CT81
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

1411621:AUC43 RS19430
gene id: 1411621:AUC43_RS19430
uniprot id: A0A0U4C9L5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

1411621:AUC43 RS08535
gene id: 1411621:AUC43_RS08535
uniprot id: A0A0U4CP40
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1411621:AUC43 RS08925
gene id: 1411621:AUC43_RS08925
uniprot id: A0A0U3SGB5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1411621:AUC43 RS05325
gene id: 1411621:AUC43_RS05325
uniprot id: A0A0U4BDB1
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1411621:AUC43 RS18585
gene id: 1411621:AUC43_RS18585
uniprot id: A0A0U4BTD1
names: Similarity
messages: Belongs to the peptidase S9C family.

1411621:AUC43 RS16700
gene id: 1411621:AUC43_RS16700
uniprot id: A0A0U4B0K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1411621:AUC43 RS09995
gene id: 1411621:AUC43_RS09995
uniprot id: A0A0U3SGV2
names: Subcellular Location Annotation
messages: Cytoplasm

1411621:AUC43 RS11375
gene id: 1411621:AUC43_RS11375
uniprot id: A0A0U4BQD2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1411621:AUC43 RS12525
gene id: 1411621:AUC43_RS12525
uniprot id: A0A0U4AQP2
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1411621:AUC43 RS07415
gene id: 1411621:AUC43_RS07415
uniprot id: A0A0U3SFL6
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS08355
gene id: 1411621:AUC43_RS08355
uniprot id: A0A0U4AA85
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

1411621:AUC43 RS14965
gene id: 1411621:AUC43_RS14965
uniprot id: A0A0U4AZS8
names: Subcellular Location Annotation
messages: Membrane

1411621:AUC43 RS04200
gene id: 1411621:AUC43_RS04200
uniprot id: A0A0U4C2H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm