1408281:Epro RS01400
gene id: 1408281:Epro_RS01400
uniprot id: A0A0G3WG87
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1408281:Epro RS05310
gene id: 1408281:Epro_RS05310
uniprot id: A0A0G3WLN0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1408281:Epro RS03280
gene id: 1408281:Epro_RS03280
uniprot id: A0A0G3WJI2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1408281:Epro RS04080
gene id: 1408281:Epro_RS04080
uniprot id: A0A0G3WHP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1408281:Epro RS03235
gene id: 1408281:Epro_RS03235
uniprot id: A0A0G3WI88
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1408281:Epro RS02365
gene id: 1408281:Epro_RS02365
uniprot id: A0A0G3WGN0
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1408281:Epro RS02925
gene id: 1408281:Epro_RS02925
uniprot id: A0A0G3WJC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1408281:Epro RS03735
gene id: 1408281:Epro_RS03735
uniprot id: A0A0G3WHJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1408281:Epro RS04625
gene id: 1408281:Epro_RS04625
uniprot id: A0A0G3WIY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1408281:Epro RS06835
gene id: 1408281:Epro_RS06835
uniprot id: A0A0G3WLC6
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1408281:Epro RS01980
gene id: 1408281:Epro_RS01980
uniprot id: A0A0G3WGF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1408281:Epro RS06370
gene id: 1408281:Epro_RS06370
uniprot id: A0A0G3WIY6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1408281:Epro RS00455
gene id: 1408281:Epro_RS00455
uniprot id: A0A0G3WHZ0
names: Subcellular Location Annotation
messages: Membrane

1408281:Epro RS01285
gene id: 1408281:Epro_RS01285
uniprot id: A0A0G3WID2
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1408281:Epro RS01985
gene id: 1408281:Epro_RS01985
uniprot id: A0A0G3WIQ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1408281:Epro RS05950
gene id: 1408281:Epro_RS05950
uniprot id: A0A0G3WKY4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1408281:Epro RS04425
gene id: 1408281:Epro_RS04425
uniprot id: A0A0G3WL61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

1408281:Epro RS05935
gene id: 1408281:Epro_RS05935
uniprot id: A0A0G3WL03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1408281:Epro RS03630
gene id: 1408281:Epro_RS03630
uniprot id: A0A0G3WKS2
names: Similarity
messages: Belongs to the TrpC family.

1408281:Epro RS01380
gene id: 1408281:Epro_RS01380
uniprot id: A0A0G3WIE8
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1408281:Epro RS05850
gene id: 1408281:Epro_RS05850
uniprot id: A0A0G3WIQ5
names: Subcellular Location Annotation
messages: Cytoplasm

1408281:Epro RS04025
gene id: 1408281:Epro_RS04025
uniprot id: A0A0G3WJV1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1408281:Epro RS03525
gene id: 1408281:Epro_RS03525
uniprot id: A0A0G3WKQ6
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

1408281:Epro RS00890
gene id: 1408281:Epro_RS00890
uniprot id: A0A0G3WI60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1408281:Epro RS01570
gene id: 1408281:Epro_RS01570
uniprot id: A0A0G3WH75
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1408281:Epro RS05065
gene id: 1408281:Epro_RS05065
uniprot id: A0A0G3WI43
names: Subcellular Location Annotation
messages: Membrane

1408281:Epro RS06700
gene id: 1408281:Epro_RS06700
uniprot id: A0A0G3WLA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1408281:Epro RS05695
gene id: 1408281:Epro_RS05695
uniprot id: A0A0G3WIM7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1408281:Epro RS00165
gene id: 1408281:Epro_RS00165
uniprot id: A0A0G3WIU1
names: Subcellular Location Annotation
messages: Membrane

1408281:Epro RS01845
gene id: 1408281:Epro_RS01845
uniprot id: A0A0G3WJR1
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1408281:Epro RS02320
gene id: 1408281:Epro_RS02320
uniprot id: A0A0G3WIX3
names: Similarity
messages: Belongs to the Skp family.

1408281:Epro RS04690
gene id: 1408281:Epro_RS04690
uniprot id: A0A0G3WLA4
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1408281:Epro RS01625
gene id: 1408281:Epro_RS01625
uniprot id: A0A0G3WH85
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1408281:Epro RS06480
gene id: 1408281:Epro_RS06480
uniprot id: A0A0G3WL97
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1408281:Epro RS03635
gene id: 1408281:Epro_RS03635
uniprot id: A0A0G3WJM6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408281:Epro RS06240
gene id: 1408281:Epro_RS06240
uniprot id: A0A0G3WL35
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1408281:Epro RS06220
gene id: 1408281:Epro_RS06220
uniprot id: A0A0G3WIW6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1408281:Epro RS00450
gene id: 1408281:Epro_RS00450
uniprot id: A0A0G3WFT6
names: Subcellular Location Annotation
messages: Membrane

1408281:Epro RS03090
gene id: 1408281:Epro_RS03090
uniprot id: A0A0G3WKK1
names: Subcellular Location Annotation
messages: Membrane

1408281:Epro RS01790
gene id: 1408281:Epro_RS01790
uniprot id: A0A0G3WHB8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1408281:Epro RS02645
gene id: 1408281:Epro_RS02645
uniprot id: A0A0G3WGU1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

1408281:Epro RS01445
gene id: 1408281:Epro_RS01445
uniprot id: A0A0G3WIE9
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1408281:Epro RS02160
gene id: 1408281:Epro_RS02160
uniprot id: A0A0G3WIS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1408281:Epro RS04640
gene id: 1408281:Epro_RS04640
uniprot id: A0A0G3WHX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1408281:Epro RS06820
gene id: 1408281:Epro_RS06820
uniprot id: A0A0G3WLF4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1408281:Epro RS05800
gene id: 1408281:Epro_RS05800
uniprot id: A0A0G3WIP5
names: Subcellular Location Annotation
messages: Membrane

1408281:Epro RS00795
gene id: 1408281:Epro_RS00795
uniprot id: A0A0G3WGT6
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1408281:Epro RS02475
gene id: 1408281:Epro_RS02475
uniprot id: A0A0G3WHQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1408281:Epro RS04585
gene id: 1408281:Epro_RS04585
uniprot id: A0A0G3WK47
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1408281:Epro RS01955
gene id: 1408281:Epro_RS01955
uniprot id: A0A0G3WGF4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408281:Epro RS02715
gene id: 1408281:Epro_RS02715
uniprot id: A0A0G3WGV7
names: Subcellular Location Annotation
messages: Membrane

1408281:Epro RS04235
gene id: 1408281:Epro_RS04235
uniprot id: A0A0G3WJZ6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1408281:Epro RS03260
gene id: 1408281:Epro_RS03260
uniprot id: A0A0G3WI93
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

1408281:Epro RS05530
gene id: 1408281:Epro_RS05530
uniprot id: A0A0G3WKU1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

1408281:Epro RS06105
gene id: 1408281:Epro_RS06105
uniprot id: A0A0G3WL37
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1408281:Epro RS04035
gene id: 1408281:Epro_RS04035
uniprot id: A0A0G3WJW6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1408281:Epro RS06190
gene id: 1408281:Epro_RS06190
uniprot id: A0A0G3WL49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

1408281:Epro RS02625
gene id: 1408281:Epro_RS02625
uniprot id: A0A0G3WJ25
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1408281:Epro RS00105
gene id: 1408281:Epro_RS00105
uniprot id: A0A0G3WFG5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1408281:Epro RS01205
gene id: 1408281:Epro_RS01205
uniprot id: A0A0G3WIB6
names: Subcellular Location Annotation
messages: Membrane

1408281:Epro RS06005
gene id: 1408281:Epro_RS06005
uniprot id: A0A0G3WL15
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408281:Epro RS01580
gene id: 1408281:Epro_RS01580
uniprot id: A0A0G3WIH0
names: Similarity
messages: Belongs to the HupF/HypC family.

1408281:Epro RS03075
gene id: 1408281:Epro_RS03075
uniprot id: A0A0G3WH77
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1408281:Epro RS03450
gene id: 1408281:Epro_RS03450
uniprot id: A0A0G3WKP8
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1408281:Epro RS02960
gene id: 1408281:Epro_RS02960
uniprot id: A0A0G3WI37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1408281:Epro RS02025
gene id: 1408281:Epro_RS02025
uniprot id: A0A0G3WIQ3
names: Similarity
messages: Belongs to the UPF0758 family.

1408281:Epro RS02270
gene id: 1408281:Epro_RS02270
uniprot id: A0A0G3WIW4
names: Subcellular Location Annotation
messages: Membrane

1408281:Epro RS03285
gene id: 1408281:Epro_RS03285
uniprot id: A0A0G3WI99
names: Similarity
messages: Belongs to the GARS family.

1408281:Epro RS01815
gene id: 1408281:Epro_RS01815
uniprot id: A0A0G3WHC3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1408281:Epro RS02060
gene id: 1408281:Epro_RS02060
uniprot id: A0A0G3WIS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1408281:Epro RS05490
gene id: 1408281:Epro_RS05490
uniprot id: A0A0G3WII3
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1408281:Epro RS06785
gene id: 1408281:Epro_RS06785
uniprot id: A0A0G3WJ52
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1408281:Epro RS01395
gene id: 1408281:Epro_RS01395
uniprot id: A0A0G3WIE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1408281:Epro RS06895
gene id: 1408281:Epro_RS06895
uniprot id: A0A0G3WLH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1408281:Epro RS01385
gene id: 1408281:Epro_RS01385
uniprot id: A0A0G3WH39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1408281:Epro RS00745
gene id: 1408281:Epro_RS00745
uniprot id: A0A0G3WI17
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1408281:Epro RS06170
gene id: 1408281:Epro_RS06170
uniprot id: A0A0G3WJV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1408281:Epro RS04950
gene id: 1408281:Epro_RS04950
uniprot id: A0A0G3WKB3
names: Similarity
messages: Belongs to the DprA/Smf family.

1408281:Epro RS04050
gene id: 1408281:Epro_RS04050
uniprot id: A0A0G3WJV5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1408281:Epro RS03925
gene id: 1408281:Epro_RS03925
uniprot id: A0A0G3WJU9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408281:Epro RS06795
gene id: 1408281:Epro_RS06795
uniprot id: A0A0G3WK61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1408281:Epro RS01230
gene id: 1408281:Epro_RS01230
uniprot id: A0A0G3WG58
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1408281:Epro RS01425
gene id: 1408281:Epro_RS01425
uniprot id: A0A0G3WG88
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1408281:Epro RS05505
gene id: 1408281:Epro_RS05505
uniprot id: A0A0G3WJJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1408281:Epro RS03325
gene id: 1408281:Epro_RS03325
uniprot id: A0A0G3WHC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1408281:Epro RS06640
gene id: 1408281:Epro_RS06640
uniprot id: A0A0G3WME9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1408281:Epro RS00155
gene id: 1408281:Epro_RS00155
uniprot id: A0A0G3WHN7
names: Subcellular Location Annotation
messages: Membrane

1408281:Epro RS05710
gene id: 1408281:Epro_RS05710
uniprot id: A0A0G3WJN2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1408281:Epro RS06095
gene id: 1408281:Epro_RS06095
uniprot id: A0A0G3WL10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1408281:Epro RS00835
gene id: 1408281:Epro_RS00835
uniprot id: A0A0G3WFZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1408281:Epro RS03825
gene id: 1408281:Epro_RS03825
uniprot id: A0A0G3WJR9
names: Similarity
messages: Belongs to the Pal lipoprotein family.

1408281:Epro RS06035
gene id: 1408281:Epro_RS06035
uniprot id: A0A0G3WJT9
names: Similarity
messages: Belongs to the LarC family.

1408281:Epro RS00525
gene id: 1408281:Epro_RS00525
uniprot id: A0A0G3WFU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1408281:Epro RS00855
gene id: 1408281:Epro_RS00855
uniprot id: A0A0G3WI34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1408281:Epro RS02780
gene id: 1408281:Epro_RS02780
uniprot id: A0A0G3WHV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1408281:Epro RS00740
gene id: 1408281:Epro_RS00740
uniprot id: A0A0G3WJ87
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1408281:Epro RS00425
gene id: 1408281:Epro_RS00425
uniprot id: A0A0G3WHY7
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1408281:Epro RS04795
gene id: 1408281:Epro_RS04795
uniprot id: A0A0G3WK84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1408281:Epro RS06580
gene id: 1408281:Epro_RS06580
uniprot id: A0A0G3WJ16
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1408281:Epro RS06295
gene id: 1408281:Epro_RS06295
uniprot id: A0A0G3WL63
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1408281:Epro RS04880
gene id: 1408281:Epro_RS04880
uniprot id: A0A0G3WKC2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1408281:Epro RS05520
gene id: 1408281:Epro_RS05520
uniprot id: A0A0G3WKS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1408281:Epro RS05455
gene id: 1408281:Epro_RS05455
uniprot id: A0A0G3WLR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1408281:Epro RS02580
gene id: 1408281:Epro_RS02580
uniprot id: A0A0G3WK51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1408281:Epro RS03355
gene id: 1408281:Epro_RS03355
uniprot id: A0A0G3WJJ6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408281:Epro RS05790
gene id: 1408281:Epro_RS05790
uniprot id: A0A0G3WM26
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1408281:Epro RS05060
gene id: 1408281:Epro_RS05060
uniprot id: A0A0G3WKD3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1408281:Epro RS02935
gene id: 1408281:Epro_RS02935
uniprot id: A0A0G3WKH4
names: Subcellular Location Annotation
messages: Membrane

1408281:Epro RS05975
gene id: 1408281:Epro_RS05975
uniprot id: A0A0G3WKY7
names: Similarity
messages: Belongs to the aspartokinase family.

1408281:Epro RS03785
gene id: 1408281:Epro_RS03785
uniprot id: A0A0G3WJS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1408281:Epro RS02860
gene id: 1408281:Epro_RS02860
uniprot id: A0A0G3WKB1
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

1408281:Epro RS00950
gene id: 1408281:Epro_RS00950
uniprot id: A0A0G3WGW5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1408281:Epro RS05250
gene id: 1408281:Epro_RS05250
uniprot id: A0A0G3WKI4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1408281:Epro RS00565
gene id: 1408281:Epro_RS00565
uniprot id: A0A0G3WI05
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1408281:Epro RS02745
gene id: 1408281:Epro_RS02745
uniprot id: A0A0G3WJ50
names: Similarity
messages: Belongs to the peptidase C40 family.

1408281:Epro RS03990
gene id: 1408281:Epro_RS03990
uniprot id: A0A0G3WIM2
names: Similarity
messages: Belongs to the UPF0045 family.

1408281:Epro RS03255
gene id: 1408281:Epro_RS03255
uniprot id: A0A0G3WJH7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408281:Epro RS02015
gene id: 1408281:Epro_RS02015
uniprot id: A0A0G3WHG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1408281:Epro RS03965
gene id: 1408281:Epro_RS03965
uniprot id: A0A0G3WKX8
names: Similarity
messages: Belongs to the UPF0047 family.

1408281:Epro RS03860
gene id: 1408281:Epro_RS03860
uniprot id: A0A0G3WJT7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1408281:Epro RS06585
gene id: 1408281:Epro_RS06585
uniprot id: A0A0G3WLB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1408281:Epro RS04460
gene id: 1408281:Epro_RS04460
uniprot id: A0A0G3WHU5
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1408281:Epro RS03565
gene id: 1408281:Epro_RS03565
uniprot id: A0A0G3WJN4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-100 inactivates the nitrogenase reductase and regulates nitrogenase activity.

1408281:Epro RS00700
gene id: 1408281:Epro_RS00700
uniprot id: A0A0G3WFX3
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1408281:Epro RS05715
gene id: 1408281:Epro_RS05715
uniprot id: A0A0G3WM12
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.

1408281:Epro RS02720
gene id: 1408281:Epro_RS02720
uniprot id: A0A0G3WJ45
names: Similarity
messages: Belongs to the peptidase S24 family.

1408281:Epro RS06550
gene id: 1408281:Epro_RS06550
uniprot id: A0A0G3WL85
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1408281:Epro RS03445
gene id: 1408281:Epro_RS03445
uniprot id: A0A0G3WIC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1408281:Epro RS03765
gene id: 1408281:Epro_RS03765
uniprot id: A0A0G3WJS1
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1408281:Epro RS06805
gene id: 1408281:Epro_RS06805
uniprot id: A0A0G3WMI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1408281:Epro RS02425
gene id: 1408281:Epro_RS02425
uniprot id: A0A0G3WHN8
names: Subcellular Location Annotation
messages: Membrane

1408281:Epro RS00850
gene id: 1408281:Epro_RS00850
uniprot id: A0A0G3WJ98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1408281:Epro RS06475
gene id: 1408281:Epro_RS06475
uniprot id: A0A0G3WJ00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

1408281:Epro RS03900
gene id: 1408281:Epro_RS03900
uniprot id: A0A0G3WJU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1408281:Epro RS02470
gene id: 1408281:Epro_RS02470
uniprot id: A0A0G3WIZ9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1408281:Epro RS04730
gene id: 1408281:Epro_RS04730
uniprot id: A0A0G3WK91
names: Similarity
messages: Belongs to the CinA family.

1408281:Epro RS01030
gene id: 1408281:Epro_RS01030
uniprot id: A0A0G3WJB8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1408281:Epro RS03850
gene id: 1408281:Epro_RS03850
uniprot id: A0A0G3WJS4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1408281:Epro RS06840
gene id: 1408281:Epro_RS06840
uniprot id: A0A0G3WJ62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1408281:Epro RS05915
gene id: 1408281:Epro_RS05915
uniprot id: A0A0G3WJR8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408281:Epro RS00130
gene id: 1408281:Epro_RS00130
uniprot id: A0A0G3WFH0
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1408281:Epro RS06670
gene id: 1408281:Epro_RS06670
uniprot id: A0A0G3WL98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1408281:Epro RS03750
gene id: 1408281:Epro_RS03750
uniprot id: A0A0G3WKU4
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1408281:Epro RS00370
gene id: 1408281:Epro_RS00370
uniprot id: A0A0G3WFS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1408281:Epro RS02595
gene id: 1408281:Epro_RS02595
uniprot id: A0A0G3WJ20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1408281:Epro RS03705
gene id: 1408281:Epro_RS03705
uniprot id: A0A0G3WKT5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1408281:Epro RS03425
gene id: 1408281:Epro_RS03425
uniprot id: A0A0G3WKP5
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1408281:Epro RS03890
gene id: 1408281:Epro_RS03890
uniprot id: A0A0G3WJT2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1408281:Epro RS00755
gene id: 1408281:Epro_RS00755
uniprot id: A0A0G3WI35
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1408281:Epro RS06770
gene id: 1408281:Epro_RS06770
uniprot id: A0A0G3WK58
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1408281:Epro RS02325
gene id: 1408281:Epro_RS02325
uniprot id: A0A0G3WHM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1408281:Epro RS06635
gene id: 1408281:Epro_RS06635
uniprot id: A0A0G3WK31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1408281:Epro RS01210
gene id: 1408281:Epro_RS01210
uniprot id: A0A0G3WH12
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1408281:Epro RS04400
gene id: 1408281:Epro_RS04400
uniprot id: A0A0G3WL56
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1408281:Epro RS00030
gene id: 1408281:Epro_RS00030
uniprot id: A0A0G3WHK6
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1408281:Epro RS05025
gene id: 1408281:Epro_RS05025
uniprot id: A0A0G3WJ49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1408281:Epro RS01915
gene id: 1408281:Epro_RS01915
uniprot id: A0A0G3WHE3
names: Similarity
messages: Belongs to the CarB family.

1408281:Epro RS04755
gene id: 1408281:Epro_RS04755
uniprot id: A0A0G3WK96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1408281:Epro RS01335
gene id: 1408281:Epro_RS01335
uniprot id: A0A0G3WH32
names: Similarity
messages: Belongs to the RecJ family.

1408281:Epro RS01700
gene id: 1408281:Epro_RS01700
uniprot id: A0A0G3WHA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1408281:Epro RS04010
gene id: 1408281:Epro_RS04010
uniprot id: A0A0G3WJW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1408281:Epro RS02995
gene id: 1408281:Epro_RS02995
uniprot id: A0A0G3WJC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1408281:Epro RS06660
gene id: 1408281:Epro_RS06660
uniprot id: A0A0G3WK37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1408281:Epro RS06200
gene id: 1408281:Epro_RS06200
uniprot id: A0A0G3WM84
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1408281:Epro RS00235
gene id: 1408281:Epro_RS00235
uniprot id: A0A0G3WGD7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

1408281:Epro RS02560
gene id: 1408281:Epro_RS02560
uniprot id: A0A0G3WJ05
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1408281:Epro RS03570
gene id: 1408281:Epro_RS03570
uniprot id: A0A0G3WIF0
names: Similarity
messages: Belongs to the OprB family.

1408281:Epro RS05450
gene id: 1408281:Epro_RS05450
uniprot id: A0A0G3WJB7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1408281:Epro RS02035
gene id: 1408281:Epro_RS02035
uniprot id: A0A0G3WIR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin thioredoxin reductase beta subunit family.
messages: Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.
messages: Heterodimer of subunit A (variable subunit) and subunit B (catalytic subunit). Heterodimeric FTR forms a complex with ferredoxin and thioredoxin.

1408281:Epro RS02620
gene id: 1408281:Epro_RS02620
uniprot id: A0A0G3WGT5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408281:Epro RS02145
gene id: 1408281:Epro_RS02145
uniprot id: A0A0G3WHI8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1408281:Epro RS06690
gene id: 1408281:Epro_RS06690
uniprot id: A0A0G3WK42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1408281:Epro RS02510
gene id: 1408281:Epro_RS02510
uniprot id: A0A0G3WIZ7
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1408281:Epro RS01835
gene id: 1408281:Epro_RS01835
uniprot id: A0A0G3WIM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1408281:Epro RS04475
gene id: 1408281:Epro_RS04475
uniprot id: A0A0G3WL70
names: Subcellular Location Annotation
messages: Membrane

1408281:Epro RS05980
gene id: 1408281:Epro_RS05980
uniprot id: A0A0G3WIS6
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1408281:Epro RS05080
gene id: 1408281:Epro_RS05080
uniprot id: A0A0G3WLI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1408281:Epro RS02825
gene id: 1408281:Epro_RS02825
uniprot id: A0A0G3WJ67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1408281:Epro RS00245
gene id: 1408281:Epro_RS00245
uniprot id: A0A0G3WHP6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408281:Epro RS05345
gene id: 1408281:Epro_RS05345
uniprot id: A0A0G3WIA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1408281:Epro RS04530
gene id: 1408281:Epro_RS04530
uniprot id: A0A0G3WL80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1408281:Epro RS06255
gene id: 1408281:Epro_RS06255
uniprot id: A0A0G3WJW9
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1408281:Epro RS00465
gene id: 1408281:Epro_RS00465
uniprot id: A0A0G3WJ44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1408281:Epro RS00515
gene id: 1408281:Epro_RS00515
uniprot id: A0A0G3WJ53
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1408281:Epro RS06330
gene id: 1408281:Epro_RS06330
uniprot id: A0A0G3WMA3
names: Subcellular Location Annotation
messages: Membrane

1408281:Epro RS03380
gene id: 1408281:Epro_RS03380
uniprot id: A0A0G3WJK1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408281:Epro RS06695
gene id: 1408281:Epro_RS06695
uniprot id: A0A0G3WMF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1408281:Epro RS03680
gene id: 1408281:Epro_RS03680
uniprot id: A0A0G3WIG6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1408281:Epro RS01390
gene id: 1408281:Epro_RS01390
uniprot id: A0A0G3WJH6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408281:Epro RS00025
gene id: 1408281:Epro_RS00025
uniprot id: A0A0G3WIR0
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1408281:Epro RS00575
gene id: 1408281:Epro_RS00575
uniprot id: A0A0G3WGP8
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1408281:Epro RS01550
gene id: 1408281:Epro_RS01550
uniprot id: A0A0G3WJK4
names: Subcellular Location Annotation
messages: Membrane

1408281:Epro RS05920
gene id: 1408281:Epro_RS05920
uniprot id: A0A0G3WM43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1408281:Epro RS00875
gene id: 1408281:Epro_RS00875
uniprot id: A0A0G3WJA1
names: Subcellular Location Annotation
messages: Membrane

1408281:Epro RS04230
gene id: 1408281:Epro_RS04230
uniprot id: A0A0G3WHR8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1408281:Epro RS04745
gene id: 1408281:Epro_RS04745
uniprot id: A0A0G3WK74
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1408281:Epro RS02215
gene id: 1408281:Epro_RS02215
uniprot id: A0A0G3WIT9
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1408281:Epro RS04090
gene id: 1408281:Epro_RS04090
uniprot id: A0A0G3WIN8
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1408281:Epro RS02200
gene id: 1408281:Epro_RS02200
uniprot id: A0A0G3WIV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1408281:Epro RS00820
gene id: 1408281:Epro_RS00820
uniprot id: A0A0G3WGU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1408281:Epro RS01830
gene id: 1408281:Epro_RS01830
uniprot id: A0A0G3WGD6
names: Similarity
messages: Belongs to the fabD family.

1408281:Epro RS01805
gene id: 1408281:Epro_RS01805
uniprot id: A0A0G3WGD2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1408281:Epro RS04150
gene id: 1408281:Epro_RS04150
uniprot id: A0A0G3WJY2
names: Similarity
messages: Belongs to the CapA family.

1408281:Epro RS01440
gene id: 1408281:Epro_RS01440
uniprot id: A0A0G3WJI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1408281:Epro RS02385
gene id: 1408281:Epro_RS02385
uniprot id: A0A0G3WIX5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1408281:Epro RS02610
gene id: 1408281:Epro_RS02610
uniprot id: A0A0G3WJ14
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408281:Epro RS06665
gene id: 1408281:Epro_RS06665
uniprot id: A0A0G3WMF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1408281:Epro RS05150
gene id: 1408281:Epro_RS05150
uniprot id: A0A0G3WKG4
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1408281:Epro RS01410
gene id: 1408281:Epro_RS01410
uniprot id: A0A0G3WH43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1408281:Epro RS01090
gene id: 1408281:Epro_RS01090
uniprot id: A0A0G3WG38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

1408281:Epro RS00500
gene id: 1408281:Epro_RS00500
uniprot id: A0A0G3WFU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1408281:Epro RS06730
gene id: 1408281:Epro_RS06730
uniprot id: A0A0G3WJ42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1408281:Epro RS03920
gene id: 1408281:Epro_RS03920
uniprot id: A0A0G3WHM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1408281:Epro RS02590
gene id: 1408281:Epro_RS02590
uniprot id: A0A0G3WGT0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1408281:Epro RS05995
gene id: 1408281:Epro_RS05995
uniprot id: A0A0G3WKZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1408281:Epro RS03745
gene id: 1408281:Epro_RS03745
uniprot id: A0A0G3WIH6
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1408281:Epro RS04225
gene id: 1408281:Epro_RS04225
uniprot id: A0A0G3WJX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1408281:Epro RS02920
gene id: 1408281:Epro_RS02920
uniprot id: A0A0G3WH51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1408281:Epro RS05945
gene id: 1408281:Epro_RS05945
uniprot id: A0A0G3WM46
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1408281:Epro RS02355
gene id: 1408281:Epro_RS02355
uniprot id: A0A0G3WK02
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1408281:Epro RS03780
gene id: 1408281:Epro_RS03780
uniprot id: A0A0G3WHK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1408281:Epro RS03830
gene id: 1408281:Epro_RS03830
uniprot id: A0A0G3WHK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1408281:Epro RS03115
gene id: 1408281:Epro_RS03115
uniprot id: A0A0G3WKK5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1408281:Epro RS02660
gene id: 1408281:Epro_RS02660
uniprot id: A0A0G3WK66
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

1408281:Epro RS01435
gene id: 1408281:Epro_RS01435
uniprot id: A0A0G3WH47
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1408281:Epro RS05985
gene id: 1408281:Epro_RS05985
uniprot id: A0A0G3WL11
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408281:Epro RS05910
gene id: 1408281:Epro_RS05910
uniprot id: A0A0G3WKZ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved Asp active site.

1408281:Epro RS02010
gene id: 1408281:Epro_RS02010
uniprot id: A0A0G3WIR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1408281:Epro RS02900
gene id: 1408281:Epro_RS02900
uniprot id: A0A0G3WJ81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1408281:Epro RS02205
gene id: 1408281:Epro_RS02205
uniprot id: A0A0G3WHJ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1408281:Epro RS04550
gene id: 1408281:Epro_RS04550
uniprot id: A0A0G3WK54
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1408281:Epro RS05320
gene id: 1408281:Epro_RS05320
uniprot id: A0A0G3WIA1
names: Similarity
messages: Belongs to the AIR synthase family.

1408281:Epro RS02555
gene id: 1408281:Epro_RS02555
uniprot id: A0A0G3WK46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1408281:Epro RS00620
gene id: 1408281:Epro_RS00620
uniprot id: A0A0G3WHZ9
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1408281:Epro RS06230
gene id: 1408281:Epro_RS06230
uniprot id: A0A0G3WJW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1408281:Epro RS05575
gene id: 1408281:Epro_RS05575
uniprot id: A0A0G3WKU5
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1408281:Epro RS00305
gene id: 1408281:Epro_RS00305
uniprot id: A0A0G3WHS1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1408281:Epro RS06125
gene id: 1408281:Epro_RS06125
uniprot id: A0A0G3WIV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1408281:Epro RS02195
gene id: 1408281:Epro_RS02195
uniprot id: A0A0G3WGJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1408281:Epro RS03330
gene id: 1408281:Epro_RS03330
uniprot id: A0A0G3WJJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1408281:Epro RS01025
gene id: 1408281:Epro_RS01025
uniprot id: A0A0G3WGY1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1408281:Epro RS03005
gene id: 1408281:Epro_RS03005
uniprot id: A0A0G3WJD8
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1408281:Epro RS01565
gene id: 1408281:Epro_RS01565
uniprot id: A0A0G3WIH7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1408281:Epro RS06020
gene id: 1408281:Epro_RS06020
uniprot id: A0A0G3WKZ8
names: Subcellular Location Annotation
messages: Membrane

1408281:Epro RS06110
gene id: 1408281:Epro_RS06110
uniprot id: A0A0G3WJV0
names: Similarity
messages: Belongs to the UPF0102 family.

1408281:Epro RS04915
gene id: 1408281:Epro_RS04915
uniprot id: A0A0G3WLF1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1408281:Epro RS02890
gene id: 1408281:Epro_RS02890
uniprot id: A0A0G3WJ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1408281:Epro RS01005
gene id: 1408281:Epro_RS01005
uniprot id: A0A0G3WJB4
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408281:Epro RS01325
gene id: 1408281:Epro_RS01325
uniprot id: A0A0G3WG75
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1408281:Epro RS06345
gene id: 1408281:Epro_RS06345
uniprot id: A0A0G3WL74
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1408281:Epro RS00805
gene id: 1408281:Epro_RS00805
uniprot id: A0A0G3WI25
names: Similarity
messages: Belongs to the class-I fumarase family.

1408281:Epro RS03265
gene id: 1408281:Epro_RS03265
uniprot id: A0A0G3WKM9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1408281:Epro RS02415
gene id: 1408281:Epro_RS02415
uniprot id: A0A0G3WGP0
names: Subcellular Location Annotation
messages: Membrane

1408281:Epro RS03460
gene id: 1408281:Epro_RS03460
uniprot id: A0A0G3WHE8
names: Similarity
messages: Belongs to the thioredoxin family.

1408281:Epro RS05675
gene id: 1408281:Epro_RS05675
uniprot id: A0A0G3WKW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1408281:Epro RS01430
gene id: 1408281:Epro_RS01430
uniprot id: A0A0G3WIF7
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1408281:Epro RS04815
gene id: 1408281:Epro_RS04815
uniprot id: A0A0G3WLC9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1408281:Epro RS02785
gene id: 1408281:Epro_RS02785
uniprot id: A0A0G3WK95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1408281:Epro RS05260
gene id: 1408281:Epro_RS05260
uniprot id: A0A0G3WLL9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1408281:Epro RS06735
gene id: 1408281:Epro_RS06735
uniprot id: A0A0G3WLE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1408281:Epro RS00330
gene id: 1408281:Epro_RS00330
uniprot id: A0A0G3WHX0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1408281:Epro RS03290
gene id: 1408281:Epro_RS03290
uniprot id: A0A0G3WKN1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1408281:Epro RS05925
gene id: 1408281:Epro_RS05925
uniprot id: A0A0G3WKY0
names: Subcellular Location Annotation
messages: Cytoplasm

1408281:Epro RS01560
gene id: 1408281:Epro_RS01560
uniprot id: A0A0G3WGA4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1408281:Epro RS05305
gene id: 1408281:Epro_RS05305
uniprot id: A0A0G3WJ96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1408281:Epro RS03545
gene id: 1408281:Epro_RS03545
uniprot id: A0A0G3WIE6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1408281:Epro RS06755
gene id: 1408281:Epro_RS06755
uniprot id: A0A0G3WLB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1408281:Epro RS00275
gene id: 1408281:Epro_RS00275
uniprot id: A0A0G3WFK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1408281:Epro RS05705
gene id: 1408281:Epro_RS05705
uniprot id: A0A0G3WKW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1408281:Epro RS05005
gene id: 1408281:Epro_RS05005
uniprot id: A0A0G3WI33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1408281:Epro RS05970
gene id: 1408281:Epro_RS05970
uniprot id: A0A0G3WM49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1408281:Epro RS04345
gene id: 1408281:Epro_RS04345
uniprot id: A0A0G3WL46
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1408281:Epro RS01010
gene id: 1408281:Epro_RS01010
uniprot id: A0A0G3WI63
names: Subcellular Location Annotation
messages: Secreted

1408281:Epro RS00270
gene id: 1408281:Epro_RS00270
uniprot id: A0A0G3WHQ3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1408281:Epro RS04450
gene id: 1408281:Epro_RS04450
uniprot id: A0A0G3WL66
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1408281:Epro RS01140
gene id: 1408281:Epro_RS01140
uniprot id: A0A0G3WG46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P(II) protein family.
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

1408281:Epro RS02840
gene id: 1408281:Epro_RS02840
uniprot id: A0A0G3WJ61
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1408281:Epro RS04065
gene id: 1408281:Epro_RS04065
uniprot id: A0A0G3WIN3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1408281:Epro RS02330
gene id: 1408281:Epro_RS02330
uniprot id: A0A0G3WJZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1408281:Epro RS00240
gene id: 1408281:Epro_RS00240
uniprot id: A0A0G3WIV8
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1408281:Epro RS02865
gene id: 1408281:Epro_RS02865
uniprot id: A0A0G3WJ65
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1408281:Epro RS04940
gene id: 1408281:Epro_RS04940
uniprot id: A0A0G3WJ33
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

1408281:Epro RS02910
gene id: 1408281:Epro_RS02910
uniprot id: A0A0G3WKG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1408281:Epro RS03610
gene id: 1408281:Epro_RS03610
uniprot id: A0A0G3WJM3
names: Similarity
messages: Belongs to the glutamine synthetase family.

1408281:Epro RS02190
gene id: 1408281:Epro_RS02190
uniprot id: A0A0G3WIT5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1408281:Epro RS03010
gene id: 1408281:Epro_RS03010
uniprot id: A0A0G3WI47
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1408281:Epro RS06055
gene id: 1408281:Epro_RS06055
uniprot id: A0A0G3WL26
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1408281:Epro RS00475
gene id: 1408281:Epro_RS00475
uniprot id: A0A0G3WFU0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1408281:Epro RS01415
gene id: 1408281:Epro_RS01415
uniprot id: A0A0G3WJI0
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408281:Epro RS00260
gene id: 1408281:Epro_RS00260
uniprot id: A0A0G3WGE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1408281:Epro RS02400
gene id: 1408281:Epro_RS02400
uniprot id: A0A0G3WHN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1408281:Epro RS05445
gene id: 1408281:Epro_RS05445
uniprot id: A0A0G3WKM2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1408281:Epro RS04110
gene id: 1408281:Epro_RS04110
uniprot id: A0A0G3WL98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1408281:Epro RS02455
gene id: 1408281:Epro_RS02455
uniprot id: A0A0G3WK24
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1408281:Epro RS06545
gene id: 1408281:Epro_RS06545
uniprot id: A0A0G3WMD5
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1408281:Epro RS00200
gene id: 1408281:Epro_RS00200
uniprot id: A0A0G3WFI7
names: Similarity
messages: Belongs to the peptidase A31 family.

1408281:Epro RS06765
gene id: 1408281:Epro_RS06765
uniprot id: A0A0G3WLE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1408281:Epro RS04630
gene id: 1408281:Epro_RS04630
uniprot id: A0A0G3WL95
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1408281:Epro RS06215
gene id: 1408281:Epro_RS06215
uniprot id: A0A0G3WL33
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408281:Epro RS02585
gene id: 1408281:Epro_RS02585
uniprot id: A0A0G3WJ10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1408281:Epro RS02810
gene id: 1408281:Epro_RS02810
uniprot id: A0A0G3WKA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1408281:Epro RS00015
gene id: 1408281:Epro_RS00015
uniprot id: A0A0G3WHL1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408281:Epro RS02895
gene id: 1408281:Epro_RS02895
uniprot id: A0A0G3WGZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1408281:Epro RS01865
gene id: 1408281:Epro_RS01865
uniprot id: A0A0G3WHD3
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1408281:Epro RS02155
gene id: 1408281:Epro_RS02155
uniprot id: A0A0G3WJW4
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1408281:Epro RS02850
gene id: 1408281:Epro_RS02850
uniprot id: A0A0G3WJ72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1408281:Epro RS03945
gene id: 1408281:Epro_RS03945
uniprot id: A0A0G3WJT8
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1408281:Epro RS01420
gene id: 1408281:Epro_RS01420
uniprot id: A0A0G3WIE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1408281:Epro RS03085
gene id: 1408281:Epro_RS03085
uniprot id: A0A0G3WI62
names: Similarity
messages: Belongs to the RecO family.

1408281:Epro RS03275
gene id: 1408281:Epro_RS03275
uniprot id: A0A0G3WHB4
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1408281:Epro RS03130
gene id: 1408281:Epro_RS03130
uniprot id: A0A0G3WJF7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1408281:Epro RS06725
gene id: 1408281:Epro_RS06725
uniprot id: A0A0G3WLA9
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1408281:Epro RS05460
gene id: 1408281:Epro_RS05460
uniprot id: A0A0G3WKK8
names: Similarity
messages: Belongs to the pyruvate kinase family.

1408281:Epro RS05000
gene id: 1408281:Epro_RS05000
uniprot id: A0A0G3WKC3
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1408281:Epro RS00685
gene id: 1408281:Epro_RS00685
uniprot id: A0A0G3WGR6
names: Similarity
messages: Belongs to the peptidase S41A family.

1408281:Epro RS02570
gene id: 1408281:Epro_RS02570
uniprot id: A0A0G3WJ15
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1408281:Epro RS03505
gene id: 1408281:Epro_RS03505
uniprot id: A0A0G3WJK3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1408281:Epro RS03755
gene id: 1408281:Epro_RS03755
uniprot id: A0A0G3WJQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1408281:Epro RS06245
gene id: 1408281:Epro_RS06245
uniprot id: A0A0G3WIX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1408281:Epro RS02990
gene id: 1408281:Epro_RS02990
uniprot id: A0A0G3WKI3
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1408281:Epro RS06935
gene id: 1408281:Epro_RS06935
uniprot id: A0A0G3WLE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1408281:Epro RS06850
gene id: 1408281:Epro_RS06850
uniprot id: A0A0G3WK73
names: Subcellular Location Annotation
messages: Membrane

1408281:Epro RS00420
gene id: 1408281:Epro_RS00420
uniprot id: A0A0G3WFT2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1408281:Epro RS02295
gene id: 1408281:Epro_RS02295
uniprot id: A0A0G3WIW9
names: Subcellular Location Annotation
messages: Membrane

1408281:Epro RS05515
gene id: 1408281:Epro_RS05515
uniprot id: A0A0G3WLX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1408281:Epro RS03615
gene id: 1408281:Epro_RS03615
uniprot id: A0A0G3WHH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1408281:Epro RS00055
gene id: 1408281:Epro_RS00055
uniprot id: A0A0G3WFF3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1408281:Epro RS05315
gene id: 1408281:Epro_RS05315
uniprot id: A0A0G3WKH7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408281:Epro RS06140
gene id: 1408281:Epro_RS06140
uniprot id: A0A0G3WM76
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1408281:Epro RS03845
gene id: 1408281:Epro_RS03845
uniprot id: A0A0G3WKV8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1408281:Epro RS06100
gene id: 1408281:Epro_RS06100
uniprot id: A0A0G3WIU7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1408281:Epro RS04095
gene id: 1408281:Epro_RS04095
uniprot id: A0A0G3WL00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1408281:Epro RS00360
gene id: 1408281:Epro_RS00360
uniprot id: A0A0G3WJ26
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

1408281:Epro RS04245
gene id: 1408281:Epro_RS04245
uniprot id: A0A0G3WL25
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1408281:Epro RS00445
gene id: 1408281:Epro_RS00445
uniprot id: A0A0G3WHX4
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

1408281:Epro RS00265
gene id: 1408281:Epro_RS00265
uniprot id: A0A0G3WIW3
names: Subcellular Location Annotation
messages: Membrane

1408281:Epro RS01120
gene id: 1408281:Epro_RS01120
uniprot id: A0A0G3WIA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1408281:Epro RS05670
gene id: 1408281:Epro_RS05670
uniprot id: A0A0G3WIM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1408281:Epro RS03810
gene id: 1408281:Epro_RS03810
uniprot id: A0A0G3WJS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TolB family.
messages: Periplasm

1408281:Epro RS05170
gene id: 1408281:Epro_RS05170
uniprot id: A0A0G3WI64
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1408281:Epro RS03800
gene id: 1408281:Epro_RS03800
uniprot id: A0A0G3WJR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1408281:Epro RS04715
gene id: 1408281:Epro_RS04715
uniprot id: A0A0G3WLA8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1408281:Epro RS02210
gene id: 1408281:Epro_RS02210
uniprot id: A0A0G3WJX2
names: Similarity
messages: Belongs to the TrpF family.

1408281:Epro RS05280
gene id: 1408281:Epro_RS05280
uniprot id: A0A0G3WJ93
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1408281:Epro RS05295
gene id: 1408281:Epro_RS05295
uniprot id: A0A0G3WI96
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1408281:Epro RS03715
gene id: 1408281:Epro_RS03715
uniprot id: A0A0G3WJR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1408281:Epro RS04885
gene id: 1408281:Epro_RS04885
uniprot id: A0A0G3WJ23
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1408281:Epro RS04220
gene id: 1408281:Epro_RS04220
uniprot id: A0A0G3WL20
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1408281:Epro RS03125
gene id: 1408281:Epro_RS03125
uniprot id: A0A0G3WH86
names: Similarity
messages: Belongs to the NDK family.

1408281:Epro RS02775
gene id: 1408281:Epro_RS02775
uniprot id: A0A0G3WJ55
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1408281:Epro RS06875
gene id: 1408281:Epro_RS06875
uniprot id: A0A0G3WK78
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1408281:Epro RS01925
gene id: 1408281:Epro_RS01925
uniprot id: A0A0G3WIN4
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

1408281:Epro RS06315
gene id: 1408281:Epro_RS06315
uniprot id: A0A0G3WIX7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408281:Epro RS03240
gene id: 1408281:Epro_RS03240
uniprot id: A0A0G3WKM5
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1408281:Epro RS00085
gene id: 1408281:Epro_RS00085
uniprot id: A0A0G3WHM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

1408281:Epro RS04750
gene id: 1408281:Epro_RS04750
uniprot id: A0A0G3WHY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1408281:Epro RS03305
gene id: 1408281:Epro_RS03305
uniprot id: A0A0G3WJI6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1408281:Epro RS00655
gene id: 1408281:Epro_RS00655
uniprot id: A0A0G3WI18
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1408281:Epro RS01900
gene id: 1408281:Epro_RS01900
uniprot id: A0A0G3WIN0
names: Similarity
messages: Belongs to the glutamine synthetase family.

1408281:Epro RS00705
gene id: 1408281:Epro_RS00705
uniprot id: A0A0G3WI26
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1408281:Epro RS05355
gene id: 1408281:Epro_RS05355
uniprot id: A0A0G3WJA2
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

1408281:Epro RS06705
gene id: 1408281:Epro_RS06705
uniprot id: A0A0G3WJ37
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1408281:Epro RS04045
gene id: 1408281:Epro_RS04045
uniprot id: A0A0G3WKZ0
names: Similarity
messages: Belongs to the ribF family.

1408281:Epro RS06870
gene id: 1408281:Epro_RS06870
uniprot id: A0A0G3WLG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1408281:Epro RS01080
gene id: 1408281:Epro_RS01080
uniprot id: A0A0G3WJC5
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1408281:Epro RS06535
gene id: 1408281:Epro_RS06535
uniprot id: A0A0G3WLA5
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1408281:Epro RS03270
gene id: 1408281:Epro_RS03270
uniprot id: A0A0G3WJG6
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1408281:Epro RS05350
gene id: 1408281:Epro_RS05350
uniprot id: A0A0G3WKK4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1408281:Epro RS05680
gene id: 1408281:Epro_RS05680
uniprot id: A0A0G3WJM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1408281:Epro RS05685
gene id: 1408281:Epro_RS05685
uniprot id: A0A0G3WM07
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408281:Epro RS03110
gene id: 1408281:Epro_RS03110
uniprot id: A0A0G3WI67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1408281:Epro RS03555
gene id: 1408281:Epro_RS03555
uniprot id: A0A0G3WJL3
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.

1408281:Epro RS05545
gene id: 1408281:Epro_RS05545
uniprot id: A0A0G3WKS4
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1408281:Epro RS06130
gene id: 1408281:Epro_RS06130
uniprot id: A0A0G3WL41
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1408281:Epro RS04015
gene id: 1408281:Epro_RS04015
uniprot id: A0A0G3WIM6
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1408281:Epro RS06720
gene id: 1408281:Epro_RS06720
uniprot id: A0A0G3WMG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1408281:Epro RS06300
gene id: 1408281:Epro_RS06300
uniprot id: A0A0G3WJX3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408281:Epro RS00885
gene id: 1408281:Epro_RS00885
uniprot id: A0A0G3WG03
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1408281:Epro RS00075
gene id: 1408281:Epro_RS00075
uniprot id: A0A0G3WHL4
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1408281:Epro RS04925
gene id: 1408281:Epro_RS04925
uniprot id: A0A0G3WI19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1408281:Epro RS06715
gene id: 1408281:Epro_RS06715
uniprot id: A0A0G3WK48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1408281:Epro RS01280
gene id: 1408281:Epro_RS01280
uniprot id: A0A0G3WG67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1408281:Epro RS05725
gene id: 1408281:Epro_RS05725
uniprot id: A0A0G3WIN2
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1408281:Epro RS01795
gene id: 1408281:Epro_RS01795
uniprot id: A0A0G3WJQ0
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1408281:Epro RS03465
gene id: 1408281:Epro_RS03465
uniprot id: A0A0G3WJL4
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1408281:Epro RS00945
gene id: 1408281:Epro_RS00945
uniprot id: A0A0G3WI69
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1408281:Epro RS03420
gene id: 1408281:Epro_RS03420
uniprot id: A0A0G3WIC4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408281:Epro RS01105
gene id: 1408281:Epro_RS01105
uniprot id: A0A0G3WJD1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1408281:Epro RS00070
gene id: 1408281:Epro_RS00070
uniprot id: A0A0G3WIS0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1408281:Epro RS02265
gene id: 1408281:Epro_RS02265
uniprot id: A0A0G3WGK7
names: Subcellular Location Annotation
messages: Membrane

1408281:Epro RS05055
gene id: 1408281:Epro_RS05055
uniprot id: A0A0G3WLH9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1408281:Epro RS01150
gene id: 1408281:Epro_RS01150
uniprot id: A0A0G3WH04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1408281:Epro RS02240
gene id: 1408281:Epro_RS02240
uniprot id: A0A0G3WIU4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1408281:Epro RS01595
gene id: 1408281:Epro_RS01595
uniprot id: A0A0G3WH80
names: Similarity
messages: Belongs to the HypE family.

1408281:Epro RS00320
gene id: 1408281:Epro_RS00320
uniprot id: A0A0G3WHV3
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1408281:Epro RS02220
gene id: 1408281:Epro_RS02220
uniprot id: A0A0G3WGJ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1408281:Epro RS01320
gene id: 1408281:Epro_RS01320
uniprot id: A0A0G3WIC5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1408281:Epro RS04575
gene id: 1408281:Epro_RS04575
uniprot id: A0A0G3WK60
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

1408281:Epro RS06590
gene id: 1408281:Epro_RS06590
uniprot id: A0A0G3WK26
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1408281:Epro RS04580
gene id: 1408281:Epro_RS04580
uniprot id: A0A0G3WIX6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1408281:Epro RS01990
gene id: 1408281:Epro_RS01990
uniprot id: A0A0G3WHF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1408281:Epro RS01575
gene id: 1408281:Epro_RS01575
uniprot id: A0A0G3WJL0
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

1408281:Epro RS00010
gene id: 1408281:Epro_RS00010
uniprot id: A0A0G3WFE2
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1408281:Epro RS05870
gene id: 1408281:Epro_RS05870
uniprot id: A0A0G3WIQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1408281:Epro RS06265
gene id: 1408281:Epro_RS06265
uniprot id: A0A0G3WL39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

1408281:Epro RS04085
gene id: 1408281:Epro_RS04085
uniprot id: A0A0G3WJX4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1408281:Epro RS00810
gene id: 1408281:Epro_RS00810
uniprot id: A0A0G3WFY9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408281:Epro RS05855
gene id: 1408281:Epro_RS05855
uniprot id: A0A0G3WKY8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408281:Epro RS06470
gene id: 1408281:Epro_RS06470
uniprot id: A0A0G3WL73
names: Subcellular Location Annotation
messages: Membrane

1408281:Epro RS01345
gene id: 1408281:Epro_RS01345
uniprot id: A0A0G3WID1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1408281:Epro RS03805
gene id: 1408281:Epro_RS03805
uniprot id: A0A0G3WHK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1408281:Epro RS04005
gene id: 1408281:Epro_RS04005
uniprot id: A0A0G3WHN4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1408281:Epro RS06810
gene id: 1408281:Epro_RS06810
uniprot id: A0A0G3WLC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1408281:Epro RS01455
gene id: 1408281:Epro_RS01455
uniprot id: A0A0G3WIG0
names: Similarity
messages: Belongs to the bacterial secretin family.

1408281:Epro RS02820
gene id: 1408281:Epro_RS02820
uniprot id: A0A0G3WGX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1408281:Epro RS06745
gene id: 1408281:Epro_RS06745
uniprot id: A0A0G3WMH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1408281:Epro RS00355
gene id: 1408281:Epro_RS00355
uniprot id: A0A0G3WGL0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1408281:Epro RS00250
gene id: 1408281:Epro_RS00250
uniprot id: A0A0G3WFJ8
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1408281:Epro RS03000
gene id: 1408281:Epro_RS03000
uniprot id: A0A0G3WH64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1408281:Epro RS01530
gene id: 1408281:Epro_RS01530
uniprot id: A0A0G3WIG1
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408281:Epro RS06080
gene id: 1408281:Epro_RS06080
uniprot id: A0A0G3WL31
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1408281:Epro RS06885
gene id: 1408281:Epro_RS06885
uniprot id: A0A0G3WLD7
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1408281:Epro RS01055
gene id: 1408281:Epro_RS01055
uniprot id: A0A0G3WJC2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1408281:Epro RS05040
gene id: 1408281:Epro_RS05040
uniprot id: A0A0G3WI38
names: Similarity
messages: Belongs to the DtxR/MntR family.

1408281:Epro RS03385
gene id: 1408281:Epro_RS03385
uniprot id: A0A0G3WIB9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1408281:Epro RS05420
gene id: 1408281:Epro_RS05420
uniprot id: A0A0G3WIC1
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

1408281:Epro RS05335
gene id: 1408281:Epro_RS05335
uniprot id: A0A0G3WLN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1408281:Epro RS00650
gene id: 1408281:Epro_RS00650
uniprot id: A0A0G3WFW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1408281:Epro RS03095
gene id: 1408281:Epro_RS03095
uniprot id: A0A0G3WJE0
names: Subcellular Location Annotation
messages: Membrane

1408281:Epro RS02020
gene id: 1408281:Epro_RS02020
uniprot id: A0A0G3WJU4
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1408281:Epro RS06645
gene id: 1408281:Epro_RS06645
uniprot id: A0A0G3WL94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1408281:Epro RS00695
gene id: 1408281:Epro_RS00695
uniprot id: A0A0G3WI10
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1408281:Epro RS04135
gene id: 1408281:Epro_RS04135
uniprot id: A0A0G3WL05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1408281:Epro RS06685
gene id: 1408281:Epro_RS06685
uniprot id: A0A0G3WLC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1408281:Epro RS01340
gene id: 1408281:Epro_RS01340
uniprot id: A0A0G3WJG8
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1408281:Epro RS06655
gene id: 1408281:Epro_RS06655
uniprot id: A0A0G3WLC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1408281:Epro RS03975
gene id: 1408281:Epro_RS03975
uniprot id: A0A0G3WJU3
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1408281:Epro RS00845
gene id: 1408281:Epro_RS00845
uniprot id: A0A0G3WGU5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1408281:Epro RS02930
gene id: 1408281:Epro_RS02930
uniprot id: A0A0G3WI32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1408281:Epro RS00385
gene id: 1408281:Epro_RS00385
uniprot id: A0A0G3WJ31
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1408281:Epro RS04435
gene id: 1408281:Epro_RS04435
uniprot id: A0A0G3WHU2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1408281:Epro RS00080
gene id: 1408281:Epro_RS00080
uniprot id: A0A0G3WFG0
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1408281:Epro RS02760
gene id: 1408281:Epro_RS02760
uniprot id: A0A0G3WJ46
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1408281:Epro RS04105
gene id: 1408281:Epro_RS04105
uniprot id: A0A0G3WHQ2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1408281:Epro RS01910
gene id: 1408281:Epro_RS01910
uniprot id: A0A0G3WIP2
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1408281:Epro RS01450
gene id: 1408281:Epro_RS01450
uniprot id: A0A0G3WG92
names: Similarity
messages: Belongs to the GcvT family.

1408281:Epro RS06780
gene id: 1408281:Epro_RS06780
uniprot id: A0A0G3WLB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1408281:Epro RS00150
gene id: 1408281:Epro_RS00150
uniprot id: A0A0G3WFH7
names: Subcellular Location Annotation
messages: Membrane

1408281:Epro RS04240
gene id: 1408281:Epro_RS04240
uniprot id: A0A0G3WIR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1408281:Epro RS01100
gene id: 1408281:Epro_RS01100
uniprot id: A0A0G3WGZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1408281:Epro RS02390
gene id: 1408281:Epro_RS02390
uniprot id: A0A0G3WGN5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1408281:Epro RS05210
gene id: 1408281:Epro_RS05210
uniprot id: A0A0G3WLK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1408281:Epro RS00100
gene id: 1408281:Epro_RS00100
uniprot id: A0A0G3WHL8
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1408281:Epro RS00825
gene id: 1408281:Epro_RS00825
uniprot id: A0A0G3WJ94
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1408281:Epro RS03470
gene id: 1408281:Epro_RS03470
uniprot id: A0A0G3WID4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1408281:Epro RS03620
gene id: 1408281:Epro_RS03620
uniprot id: A0A0G3WJP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1408281:Epro RS00050
gene id: 1408281:Epro_RS00050
uniprot id: A0A0G3WHL0
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1408281:Epro RS06160
gene id: 1408281:Epro_RS06160
uniprot id: A0A0G3WIV7
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

1408281:Epro RS01360
gene id: 1408281:Epro_RS01360
uniprot id: A0A0G3WH36
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1408281:Epro RS06085
gene id: 1408281:Epro_RS06085
uniprot id: A0A0G3WJU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1408281:Epro RS01840
gene id: 1408281:Epro_RS01840
uniprot id: A0A0G3WHC7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1408281:Epro RS06760
gene id: 1408281:Epro_RS06760
uniprot id: A0A0G3WJ47
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1408281:Epro RS06595
gene id: 1408281:Epro_RS06595
uniprot id: A0A0G3WME4
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1408281:Epro RS05155
gene id: 1408281:Epro_RS05155
uniprot id: A0A0G3WJ74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1408281:Epro RS05990
gene id: 1408281:Epro_RS05990
uniprot id: A0A0G3WM54
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1408281:Epro RS06650
gene id: 1408281:Epro_RS06650
uniprot id: A0A0G3WJ27
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1408281:Epro RS02790
gene id: 1408281:Epro_RS02790
uniprot id: A0A0G3WJ51
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408281:Epro RS03080
gene id: 1408281:Epro_RS03080
uniprot id: A0A0G3WJE9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1408281:Epro RS04545
gene id: 1408281:Epro_RS04545
uniprot id: A0A0G3WHV5
names: Similarity
messages: Belongs to the CutA family.

1408281:Epro RS03350
gene id: 1408281:Epro_RS03350
uniprot id: A0A0G3WHC9
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1408281:Epro RS02260
gene id: 1408281:Epro_RS02260
uniprot id: A0A0G3WIU9
names: Similarity
messages: Belongs to the GSP E family.

1408281:Epro RS03695
gene id: 1408281:Epro_RS03695
uniprot id: A0A0G3WHJ0
names: Similarity
messages: Belongs to the UPF0234 family.

1408281:Epro RS01475
gene id: 1408281:Epro_RS01475
uniprot id: A0A0G3WG96
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1408281:Epro RS02180
gene id: 1408281:Epro_RS02180
uniprot id: A0A0G3WHJ4
names: Cofactor
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

1408281:Epro RS03625
gene id: 1408281:Epro_RS03625
uniprot id: A0A0G3WIF8
names: Similarity
messages: Belongs to the TrpF family.

1408281:Epro RS05405
gene id: 1408281:Epro_RS05405
uniprot id: A0A0G3WJA9
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1408281:Epro RS04705
gene id: 1408281:Epro_RS04705
uniprot id: A0A0G3WK86
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1408281:Epro RS00440
gene id: 1408281:Epro_RS00440
uniprot id: A0A0G3WJ39
names: Subcellular Location Annotation
messages: Cytoplasm

1408281:Epro RS03915
gene id: 1408281:Epro_RS03915
uniprot id: A0A0G3WJT6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1408281:Epro RS01135
gene id: 1408281:Epro_RS01135
uniprot id: A0A0G3WI91
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1408281:Epro RS03430
gene id: 1408281:Epro_RS03430
uniprot id: A0A0G3WJJ0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1408281:Epro RS04145
gene id: 1408281:Epro_RS04145
uniprot id: A0A0G3WHQ6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408281:Epro RS03100
gene id: 1408281:Epro_RS03100
uniprot id: A0A0G3WH81
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1408281:Epro RS00520
gene id: 1408281:Epro_RS00520
uniprot id: A0A0G3WHY6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1408281:Epro RS02225
gene id: 1408281:Epro_RS02225
uniprot id: A0A0G3WIV4
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1408281:Epro RS00860
gene id: 1408281:Epro_RS00860
uniprot id: A0A0G3WFZ9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1408281:Epro RS01250
gene id: 1408281:Epro_RS01250
uniprot id: A0A0G3WIB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1408281:Epro RS04995
gene id: 1408281:Epro_RS04995
uniprot id: A0A0G3WLG8
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1408281:Epro RS01780
gene id: 1408281:Epro_RS01780
uniprot id: A0A0G3WGC9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1408281:Epro RS01190
gene id: 1408281:Epro_RS01190
uniprot id: A0A0G3WIA0
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1408281:Epro RS05015
gene id: 1408281:Epro_RS05015
uniprot id: A0A0G3WKE4
names: Similarity
messages: Belongs to the OprB family.

1408281:Epro RS06920
gene id: 1408281:Epro_RS06920
uniprot id: A0A0G3WLH6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1408281:Epro RS06460
gene id: 1408281:Epro_RS06460
uniprot id: A0A0G3WJZ9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1408281:Epro RS01555
gene id: 1408281:Epro_RS01555
uniprot id: A0A0G3WIG5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408281:Epro RS01880
gene id: 1408281:Epro_RS01880
uniprot id: A0A0G3WGE2
names: Similarity
messages: Belongs to the glutamate synthase family.

1408281:Epro RS00110
gene id: 1408281:Epro_RS00110
uniprot id: A0A0G3WHM7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1408281:Epro RS04785
gene id: 1408281:Epro_RS04785
uniprot id: A0A0G3WJ06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1408281:Epro RS06225
gene id: 1408281:Epro_RS06225
uniprot id: A0A0G3WL54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1408281:Epro RS00605
gene id: 1408281:Epro_RS00605
uniprot id: A0A0G3WJ68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1408281:Epro RS01515
gene id: 1408281:Epro_RS01515
uniprot id: A0A0G3WIG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1408281:Epro RS04465
gene id: 1408281:Epro_RS04465
uniprot id: A0A0G3WK38
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1408281:Epro RS05415
gene id: 1408281:Epro_RS05415
uniprot id: A0A0G3WKJ6
names: Subcellular Location Annotation
messages: Membrane

1408281:Epro RS00555
gene id: 1408281:Epro_RS00555
uniprot id: A0A0G3WHZ1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1408281:Epro RS02065
gene id: 1408281:Epro_RS02065
uniprot id: A0A0G3WHH3
names: Subcellular Location Annotation
messages: Membrane

1408281:Epro RS00800
gene id: 1408281:Epro_RS00800
uniprot id: A0A0G3WJ91
names: Similarity
messages: Belongs to the class-I fumarase family.

1408281:Epro RS02945
gene id: 1408281:Epro_RS02945
uniprot id: A0A0G3WJC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1408281:Epro RS00920
gene id: 1408281:Epro_RS00920
uniprot id: A0A0G3WGW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1408281:Epro RS02120
gene id: 1408281:Epro_RS02120
uniprot id: A0A0G3WJW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1408281:Epro RS02875
gene id: 1408281:Epro_RS02875
uniprot id: A0A0G3WJ77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1408281:Epro RS01535
gene id: 1408281:Epro_RS01535
uniprot id: A0A0G3WGA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1408281:Epro RS03550
gene id: 1408281:Epro_RS03550
uniprot id: A0A0G3WKR0
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1408281:Epro RS03365
gene id: 1408281:Epro_RS03365
uniprot id: A0A0G3WKN9
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1408281:Epro RS01195
gene id: 1408281:Epro_RS01195
uniprot id: A0A0G3WG56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1408281:Epro RS02185
gene id: 1408281:Epro_RS02185
uniprot id: A0A0G3WJW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1408281:Epro RS00595
gene id: 1408281:Epro_RS00595
uniprot id: A0A0G3WI09
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1408281:Epro RS02965
gene id: 1408281:Epro_RS02965
uniprot id: A0A0G3WKH8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1408281:Epro RS06710
gene id: 1408281:Epro_RS06710
uniprot id: A0A0G3WLD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1408281:Epro RS06825
gene id: 1408281:Epro_RS06825
uniprot id: A0A0G3WK68
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1408281:Epro RS04770
gene id: 1408281:Epro_RS04770
uniprot id: A0A0G3WK80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1408281:Epro RS05175
gene id: 1408281:Epro_RS05175
uniprot id: A0A0G3WKG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1408281:Epro RS00190
gene id: 1408281:Epro_RS00190
uniprot id: A0A0G3WIU6
names: Subcellular Location Annotation
messages: Membrane

1408281:Epro RS01975
gene id: 1408281:Epro_RS01975
uniprot id: A0A0G3WIP3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1408281:Epro RS01245
gene id: 1408281:Epro_RS01245
uniprot id: A0A0G3WJF1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408281:Epro RS03595
gene id: 1408281:Epro_RS03595
uniprot id: A0A0G3WJN8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1408281:Epro RS06865
gene id: 1408281:Epro_RS06865
uniprot id: A0A0G3WJ66
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1408281:Epro RS04445
gene id: 1408281:Epro_RS04445
uniprot id: A0A0G3WIV2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1408281:Epro RS05470
gene id: 1408281:Epro_RS05470
uniprot id: A0A0G3WKM6
names: Subcellular Location Annotation
messages: Membrane

1408281:Epro RS05655
gene id: 1408281:Epro_RS05655
uniprot id: A0A0G3WJM2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1408281:Epro RS01540
gene id: 1408281:Epro_RS01540
uniprot id: A0A0G3WIH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1408281:Epro RS00670
gene id: 1408281:Epro_RS00670
uniprot id: A0A0G3WI06
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1408281:Epro RS06565
gene id: 1408281:Epro_RS06565
uniprot id: A0A0G3WK21
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1408281:Epro RS00490
gene id: 1408281:Epro_RS00490
uniprot id: A0A0G3WJ48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1408281:Epro RS02530
gene id: 1408281:Epro_RS02530
uniprot id: A0A0G3WK40
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1408281:Epro RS03310
gene id: 1408281:Epro_RS03310
uniprot id: A0A0G3WIA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1408281:Epro RS02140
gene id: 1408281:Epro_RS02140
uniprot id: A0A0G3WIU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1408281:Epro RS03515
gene id: 1408281:Epro_RS03515
uniprot id: A0A0G3WJM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1408281:Epro RS03135
gene id: 1408281:Epro_RS03135
uniprot id: A0A0G3WI71
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1408281:Epro RS01820
gene id: 1408281:Epro_RS01820
uniprot id: A0A0G3WJQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1408281:Epro RS04740
gene id: 1408281:Epro_RS04740
uniprot id: A0A0G3WLB3
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1408281:Epro RS01165
gene id: 1408281:Epro_RS01165
uniprot id: A0A0G3WG51
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408281:Epro RS06305
gene id: 1408281:Epro_RS06305
uniprot id: A0A0G3WM98
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1408281:Epro RS04440
gene id: 1408281:Epro_RS04440
uniprot id: A0A0G3WK34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1408281:Epro RS00600
gene id: 1408281:Epro_RS00600
uniprot id: A0A0G3WGQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1408281:Epro RS01265
gene id: 1408281:Epro_RS01265
uniprot id: A0A0G3WH20
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1408281:Epro RS00470
gene id: 1408281:Epro_RS00470
uniprot id: A0A0G3WHY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1408281:Epro RS00185
gene id: 1408281:Epro_RS00185
uniprot id: A0A0G3WGD1
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1408281:Epro RS03370
gene id: 1408281:Epro_RS03370
uniprot id: A0A0G3WJI1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1408281:Epro RS02485
gene id: 1408281:Epro_RS02485
uniprot id: A0A0G3WIZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1408281:Epro RS00915
gene id: 1408281:Epro_RS00915
uniprot id: A0A0G3WI65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1408281:Epro RS06455
gene id: 1408281:Epro_RS06455
uniprot id: A0A0G3WL93
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1408281:Epro RS03950
gene id: 1408281:Epro_RS03950
uniprot id: A0A0G3WHM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1408281:Epro RS06880
gene id: 1408281:Epro_RS06880
uniprot id: A0A0G3WMJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1408281:Epro RS02755
gene id: 1408281:Epro_RS02755
uniprot id: A0A0G3WK90
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408281:Epro RS03535
gene id: 1408281:Epro_RS03535
uniprot id: A0A0G3WHG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1408281:Epro RS04525
gene id: 1408281:Epro_RS04525
uniprot id: A0A0G3WIW7
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

1408281:Epro RS04765
gene id: 1408281:Epro_RS04765
uniprot id: A0A0G3WLB8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1408281:Epro RS00480
gene id: 1408281:Epro_RS00480
uniprot id: A0A0G3WHZ4
names: Subcellular Location Annotation
messages: Membrane

1408281:Epro RS04540
gene id: 1408281:Epro_RS04540
uniprot id: A0A0G3WK39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1408281:Epro RS02290
gene id: 1408281:Epro_RS02290
uniprot id: A0A0G3WGL2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1408281:Epro RS05765
gene id: 1408281:Epro_RS05765
uniprot id: A0A0G3WM22
names: Similarity
messages: Belongs to the ParB family.

1408281:Epro RS03895
gene id: 1408281:Epro_RS03895
uniprot id: A0A0G3WHM1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408281:Epro RS00340
gene id: 1408281:Epro_RS00340
uniprot id: A0A0G3WJ21
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1408281:Epro RS03335
gene id: 1408281:Epro_RS03335
uniprot id: A0A0G3WIA9
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

1408281:Epro RS01035
gene id: 1408281:Epro_RS01035
uniprot id: A0A0G3WI68
names: Subcellular Location Annotation
messages: Membrane

1408281:Epro RS06575
gene id: 1408281:Epro_RS06575
uniprot id: A0A0G3WL89
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1408281:Epro RS02835
gene id: 1408281:Epro_RS02835
uniprot id: A0A0G3WKA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1408281:Epro RS01920
gene id: 1408281:Epro_RS01920
uniprot id: A0A0G3WJS6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1408281:Epro RS06815
gene id: 1408281:Epro_RS06815
uniprot id: A0A0G3WJ57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1408281:Epro RS01585
gene id: 1408281:Epro_RS01585
uniprot id: A0A0G3WGA7
names: Similarity
messages: Belongs to the LOG family.

1408281:Epro RS02980
gene id: 1408281:Epro_RS02980
uniprot id: A0A0G3WJD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1408281:Epro RS01365
gene id: 1408281:Epro_RS01365
uniprot id: A0A0G3WJH2
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1408281:Epro RS02905
gene id: 1408281:Epro_RS02905
uniprot id: A0A0G3WHX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1408281:Epro RS03645
gene id: 1408281:Epro_RS03645
uniprot id: A0A0G3WJP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1408281:Epro RS04470
gene id: 1408281:Epro_RS04470
uniprot id: A0A0G3WIV6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1408281:Epro RS06740
gene id: 1408281:Epro_RS06740
uniprot id: A0A0G3WK53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1408281:Epro RS05745
gene id: 1408281:Epro_RS05745
uniprot id: A0A0G3WKV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1408281:Epro RS02515
gene id: 1408281:Epro_RS02515
uniprot id: A0A0G3WGR4
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1408281:Epro RS05440
gene id: 1408281:Epro_RS05440
uniprot id: A0A0G3WIC8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1408281:Epro RS02305
gene id: 1408281:Epro_RS02305
uniprot id: A0A0G3WJZ2
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1408281:Epro RS01050
gene id: 1408281:Epro_RS01050
uniprot id: A0A0G3WGY5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1408281:Epro RS01850
gene id: 1408281:Epro_RS01850
uniprot id: A0A0G3WIL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.