1389489:O159 RS08840
gene id: 1389489:O159_RS08840
uniprot id: U3PEG0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1389489:O159 RS02910
gene id: 1389489:O159_RS02910
uniprot id: U3P4Y1
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS02500
gene id: 1389489:O159_RS02500
uniprot id: U3PB73
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1389489:O159 RS07910
gene id: 1389489:O159_RS07910
uniprot id: U3PDY5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1389489:O159 RS05315
gene id: 1389489:O159_RS05315
uniprot id: U3P635
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1389489:O159 RS05510
gene id: 1389489:O159_RS05510
uniprot id: U3P671
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1389489:O159 RS11540
gene id: 1389489:O159_RS11540
uniprot id: U3PFQ8
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1389489:O159 RS09155
gene id: 1389489:O159_RS09155
uniprot id: U3P6U0
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS01935
gene id: 1389489:O159_RS01935
uniprot id: U3P2T5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1389489:O159 RS09760
gene id: 1389489:O159_RS09760
uniprot id: U3PET9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1389489:O159 RS07165
gene id: 1389489:O159_RS07165
uniprot id: U3PDJ8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1389489:O159 RS06500
gene id: 1389489:O159_RS06500
uniprot id: U3PD98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1389489:O159 RS09115
gene id: 1389489:O159_RS09115
uniprot id: U3PBA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1389489:O159 RS05670
gene id: 1389489:O159_RS05670
uniprot id: U3P8S2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1389489:O159 RS02585
gene id: 1389489:O159_RS02585
uniprot id: U3P5N4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS10600
gene id: 1389489:O159_RS10600
uniprot id: U3P9W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1389489:O159 RS05775
gene id: 1389489:O159_RS05775
uniprot id: U3PCX7
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1389489:O159 RS12760
gene id: 1389489:O159_RS12760
uniprot id: U3PD62
names: Similarity
messages: Belongs to the citrate synthase family.

1389489:O159 RS01905
gene id: 1389489:O159_RS01905
uniprot id: U3P593
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1389489:O159 RS04740
gene id: 1389489:O159_RS04740
uniprot id: U3P4B6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1389489:O159 RS02130
gene id: 1389489:O159_RS02130
uniprot id: U3P5D4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1389489:O159 RS01735
gene id: 1389489:O159_RS01735
uniprot id: U3P567
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1389489:O159 RS05285
gene id: 1389489:O159_RS05285
uniprot id: U3P4L3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1389489:O159 RS04780
gene id: 1389489:O159_RS04780
uniprot id: U3P8A9
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1389489:O159 RS07880
gene id: 1389489:O159_RS07880
uniprot id: U3PAB8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1389489:O159 RS07130
gene id: 1389489:O159_RS07130
uniprot id: U3PDJ6
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS05370
gene id: 1389489:O159_RS05370
uniprot id: U3P8M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1389489:O159 RS07245
gene id: 1389489:O159_RS07245
uniprot id: U3P5Q5
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1389489:O159 RS10475
gene id: 1389489:O159_RS10475
uniprot id: U3P9T6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS08530
gene id: 1389489:O159_RS08530
uniprot id: U3P6F7
names: Similarity
messages: Belongs to the EfeM/EfeO family.

1389489:O159 RS05355
gene id: 1389489:O159_RS05355
uniprot id: U3P743
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1389489:O159 RS12700
gene id: 1389489:O159_RS12700
uniprot id: U3PD55
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1389489:O159 RS06020
gene id: 1389489:O159_RS06020
uniprot id: U3P928
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1389489:O159 RS10500
gene id: 1389489:O159_RS10500
uniprot id: U3P9U1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1389489:O159 RS10660
gene id: 1389489:O159_RS10660
uniprot id: U3P7P3
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1389489:O159 RS08440
gene id: 1389489:O159_RS08440
uniprot id: U3P7U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1389489:O159 RS04980
gene id: 1389489:O159_RS04980
uniprot id: U3P4G0
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1389489:O159 RS08625
gene id: 1389489:O159_RS08625
uniprot id: U3P8V8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1389489:O159 RS03420
gene id: 1389489:O159_RS03420
uniprot id: U3P5A3
names: Similarity
messages: Belongs to the Nth/MutY family.

1389489:O159 RS08025
gene id: 1389489:O159_RS08025
uniprot id: U3P649
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1389489:O159 RS03300
gene id: 1389489:O159_RS03300
uniprot id: U3P7L8
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1389489:O159 RS01990
gene id: 1389489:O159_RS01990
uniprot id: U3P4G3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS08525
gene id: 1389489:O159_RS08525
uniprot id: U3P8U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1389489:O159 RS09130
gene id: 1389489:O159_RS09130
uniprot id: U3P6T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1389489:O159 RS03280
gene id: 1389489:O159_RS03280
uniprot id: U3PBP6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1389489:O159 RS02095
gene id: 1389489:O159_RS02095
uniprot id: U3P6X0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1389489:O159 RS08375
gene id: 1389489:O159_RS08375
uniprot id: U3PE94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1389489:O159 RS03350
gene id: 1389489:O159_RS03350
uniprot id: U3P7M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1389489:O159 RS07775
gene id: 1389489:O159_RS07775
uniprot id: U3PF48
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1389489:O159 RS04455
gene id: 1389489:O159_RS04455
uniprot id: U3P6M5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS04795
gene id: 1389489:O159_RS04795
uniprot id: U3P4C5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1389489:O159 RS09140
gene id: 1389489:O159_RS09140
uniprot id: U3PBB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1389489:O159 RS06135
gene id: 1389489:O159_RS06135
uniprot id: U3PD42
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS08665
gene id: 1389489:O159_RS08665
uniprot id: U3PB26
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1389489:O159 RS08435
gene id: 1389489:O159_RS08435
uniprot id: U3P6E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.
messages: Membrane

1389489:O159 RS05340
gene id: 1389489:O159_RS05340
uniprot id: U3P639
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1389489:O159 RS08615
gene id: 1389489:O159_RS08615
uniprot id: U3PB19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1389489:O159 RS10665
gene id: 1389489:O159_RS10665
uniprot id: U3P922
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1389489:O159 RS10865
gene id: 1389489:O159_RS10865
uniprot id: U3PCA4
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS01995
gene id: 1389489:O159_RS01995
uniprot id: U3P6U7
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1389489:O159 RS04545
gene id: 1389489:O159_RS04545
uniprot id: U3P482
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1389489:O159 RS12840
gene id: 1389489:O159_RS12840
uniprot id: U3PA42
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1389489:O159 RS04265
gene id: 1389489:O159_RS04265
uniprot id: U3PC37
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS12480
gene id: 1389489:O159_RS12480
uniprot id: U3PD09
names: Function
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1389489:O159 RS10000
gene id: 1389489:O159_RS10000
uniprot id: U3PBS6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1389489:O159 RS09475
gene id: 1389489:O159_RS09475
uniprot id: U3P8E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1389489:O159 RS12855
gene id: 1389489:O159_RS12855
uniprot id: U3PB08
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS07195
gene id: 1389489:O159_RS07195
uniprot id: U3P5P7
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1389489:O159 RS03085
gene id: 1389489:O159_RS03085
uniprot id: U3P3J8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

1389489:O159 RS03310
gene id: 1389489:O159_RS03310
uniprot id: U3P640
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

1389489:O159 RS12880
gene id: 1389489:O159_RS12880
uniprot id: U3PB13
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1389489:O159 RS02190
gene id: 1389489:O159_RS02190
uniprot id: U3P4J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1389489:O159 RS02235
gene id: 1389489:O159_RS02235
uniprot id: U3P303
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1389489:O159 RS10820
gene id: 1389489:O159_RS10820
uniprot id: U3PC85
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1389489:O159 RS04765
gene id: 1389489:O159_RS04765
uniprot id: U3P6T1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1389489:O159 RS09735
gene id: 1389489:O159_RS09735
uniprot id: U3PBL9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1389489:O159 RS04275
gene id: 1389489:O159_RS04275
uniprot id: U3P446
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS02765
gene id: 1389489:O159_RS02765
uniprot id: U3P4V8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1389489:O159 RS00615
gene id: 1389489:O159_RS00615
uniprot id: U3P285
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1389489:O159 RS01930
gene id: 1389489:O159_RS01930
uniprot id: U3P597
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1389489:O159 RS02420
gene id: 1389489:O159_RS02420
uniprot id: U3P734
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1389489:O159 RS07285
gene id: 1389489:O159_RS07285
uniprot id: U3PDL7
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

1389489:O159 RS08940
gene id: 1389489:O159_RS08940
uniprot id: U3PB77
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1389489:O159 RS00455
gene id: 1389489:O159_RS00455
uniprot id: U3P262
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS02755
gene id: 1389489:O159_RS02755
uniprot id: U3P5R5
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1389489:O159 RS10465
gene id: 1389489:O159_RS10465
uniprot id: U3PC02
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1389489:O159 RS07120
gene id: 1389489:O159_RS07120
uniprot id: U3P720
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

1389489:O159 RS08985
gene id: 1389489:O159_RS08985
uniprot id: U3P908
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1389489:O159 RS00035
gene id: 1389489:O159_RS00035
uniprot id: U3P3F6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1389489:O159 RS06185
gene id: 1389489:O159_RS06185
uniprot id: U3P967
names: Similarity
messages: Belongs to the CdaR family.

1389489:O159 RS12755
gene id: 1389489:O159_RS12755
uniprot id: U3PA30
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

1389489:O159 RS09110
gene id: 1389489:O159_RS09110
uniprot id: U3P875
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

1389489:O159 RS09720
gene id: 1389489:O159_RS09720
uniprot id: U3P9D0
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1389489:O159 RS03810
gene id: 1389489:O159_RS03810
uniprot id: U3PBX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1389489:O159 RS09745
gene id: 1389489:O159_RS09745
uniprot id: U3P9D5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1389489:O159 RS08750
gene id: 1389489:O159_RS08750
uniprot id: U3P6K0
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Reversible hydration of carbon dioxide.

1389489:O159 RS09740
gene id: 1389489:O159_RS09740
uniprot id: U3PET5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1389489:O159 RS04105
gene id: 1389489:O159_RS04105
uniprot id: U3PC15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1389489:O159 RS01515
gene id: 1389489:O159_RS01515
uniprot id: U3P6L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1389489:O159 RS09195
gene id: 1389489:O159_RS09195
uniprot id: U3PEK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1389489:O159 RS03405
gene id: 1389489:O159_RS03405
uniprot id: U3PBR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1389489:O159 RS00220
gene id: 1389489:O159_RS00220
uniprot id: U3P4H2
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS06345
gene id: 1389489:O159_RS06345
uniprot id: U3PD78
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1389489:O159 RS07450
gene id: 1389489:O159_RS07450
uniprot id: U3P781
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1389489:O159 RS12455
gene id: 1389489:O159_RS12455
uniprot id: U3PD06
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1389489:O159 RS00015
gene id: 1389489:O159_RS00015
uniprot id: U3P5U6
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1389489:O159 RS00660
gene id: 1389489:O159_RS00660
uniprot id: U3P687
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS01520
gene id: 1389489:O159_RS01520
uniprot id: U3PAP6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1389489:O159 RS07200
gene id: 1389489:O159_RS07200
uniprot id: U3P731
names: Similarity
messages: Belongs to the glutamine synthetase family.

1389489:O159 RS03020
gene id: 1389489:O159_RS03020
uniprot id: U3P7E1
names: Subcellular Location Annotation
messages: Cytoplasm

1389489:O159 RS06540
gene id: 1389489:O159_RS06540
uniprot id: U3P6S7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1389489:O159 RS01225
gene id: 1389489:O159_RS01225
uniprot id: U3PAK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1389489:O159 RS08510
gene id: 1389489:O159_RS08510
uniprot id: U3P7W2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1389489:O159 RS08555
gene id: 1389489:O159_RS08555
uniprot id: U3P6G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1389489:O159 RS07350
gene id: 1389489:O159_RS07350
uniprot id: U3P9Y3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS08110
gene id: 1389489:O159_RS08110
uniprot id: U3PAJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

1389489:O159 RS12040
gene id: 1389489:O159_RS12040
uniprot id: U3P9S0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS05295
gene id: 1389489:O159_RS05295
uniprot id: U3P8K8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS05755
gene id: 1389489:O159_RS05755
uniprot id: U3P7B7
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS07395
gene id: 1389489:O159_RS07395
uniprot id: U3P772
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1389489:O159 RS06325
gene id: 1389489:O159_RS06325
uniprot id: U3P7N9
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1389489:O159 RS09330
gene id: 1389489:O159_RS09330
uniprot id: U3P8B9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1389489:O159 RS00480
gene id: 1389489:O159_RS00480
uniprot id: U3P265
names: Similarity
messages: Belongs to the peptidase M13 family.

1389489:O159 RS03815
gene id: 1389489:O159_RS03815
uniprot id: U3P6B9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS03890
gene id: 1389489:O159_RS03890
uniprot id: U3P5H1
names: Similarity
messages: Belongs to the DEAD box helicase family.

1389489:O159 RS01610
gene id: 1389489:O159_RS01610
uniprot id: U3P4A3
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS03250
gene id: 1389489:O159_RS03250
uniprot id: U3P7L0
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1389489:O159 RS02970
gene id: 1389489:O159_RS02970
uniprot id: U3P4Z0
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS09120
gene id: 1389489:O159_RS09120
uniprot id: U3PEJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1389489:O159 RS02105
gene id: 1389489:O159_RS02105
uniprot id: U3P5D0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1389489:O159 RS15810
gene id: 1389489:O159_RS15810
uniprot id: U3P8S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm

1389489:O159 RS05835
gene id: 1389489:O159_RS05835
uniprot id: U3P4Z9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1389489:O159 RS05195
gene id: 1389489:O159_RS05195
uniprot id: U3P8I8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1389489:O159 RS04070
gene id: 1389489:O159_RS04070
uniprot id: U3P7Y5
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1389489:O159 RS07900
gene id: 1389489:O159_RS07900
uniprot id: U3P7G0
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1389489:O159 RS05790
gene id: 1389489:O159_RS05790
uniprot id: U3P6F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1389489:O159 RS12885
gene id: 1389489:O159_RS12885
uniprot id: U3P8W1
names: Similarity
messages: Belongs to the thioredoxin family.

1389489:O159 RS09460
gene id: 1389489:O159_RS09460
uniprot id: U3PEP5
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1389489:O159 RS00490
gene id: 1389489:O159_RS00490
uniprot id: U3P661
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1389489:O159 RS10790
gene id: 1389489:O159_RS10790
uniprot id: U3P949
names: Similarity
messages: Belongs to the DnaX/STICHEL family.

1389489:O159 RS03670
gene id: 1389489:O159_RS03670
uniprot id: U3P5E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1389489:O159 RS04495
gene id: 1389489:O159_RS04495
uniprot id: U3P858
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1389489:O159 RS06750
gene id: 1389489:O159_RS06750
uniprot id: U3P5G1
names: Similarity
messages: Belongs to the CsoR family.

1389489:O159 RS05310
gene id: 1389489:O159_RS05310
uniprot id: U3P4L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1389489:O159 RS06980
gene id: 1389489:O159_RS06980
uniprot id: U3PDH3
names: Similarity
messages: Belongs to the peptidase M1 family.

1389489:O159 RS06910
gene id: 1389489:O159_RS06910
uniprot id: U3P6Y8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1389489:O159 RS05695
gene id: 1389489:O159_RS05695
uniprot id: U3P8S7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1389489:O159 RS04605
gene id: 1389489:O159_RS04605
uniprot id: U3P491
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1389489:O159 RS02100
gene id: 1389489:O159_RS02100
uniprot id: U3PAY5
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1389489:O159 RS09170
gene id: 1389489:O159_RS09170
uniprot id: U3PEJ8
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1389489:O159 RS04590
gene id: 1389489:O159_RS04590
uniprot id: U3P874
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1389489:O159 RS10145
gene id: 1389489:O159_RS10145
uniprot id: U3P9L9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1389489:O159 RS04040
gene id: 1389489:O159_RS04040
uniprot id: U3P5J2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1389489:O159 RS05850
gene id: 1389489:O159_RS05850
uniprot id: U3PCY9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

1389489:O159 RS10920
gene id: 1389489:O159_RS10920
uniprot id: U3PFH1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1389489:O159 RS06860
gene id: 1389489:O159_RS06860
uniprot id: U3P6X9
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1389489:O159 RS02820
gene id: 1389489:O159_RS02820
uniprot id: U3P5S5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1389489:O159 RS05575
gene id: 1389489:O159_RS05575
uniprot id: U3P784
names: Similarity
messages: Belongs to the glutamate synthase family.

1389489:O159 RS04155
gene id: 1389489:O159_RS04155
uniprot id: U3P7Z7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

1389489:O159 RS09675
gene id: 1389489:O159_RS09675
uniprot id: U3P759
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1389489:O159 RS09515
gene id: 1389489:O159_RS09515
uniprot id: U3P992
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS03690
gene id: 1389489:O159_RS03690
uniprot id: U3P5E4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS10495
gene id: 1389489:O159_RS10495
uniprot id: U3PF67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1389489:O159 RS07405
gene id: 1389489:O159_RS07405
uniprot id: U3PDN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1389489:O159 RS03025
gene id: 1389489:O159_RS03025
uniprot id: U3PBI2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1389489:O159 RS07970
gene id: 1389489:O159_RS07970
uniprot id: U3P8I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1389489:O159 RS06025
gene id: 1389489:O159_RS06025
uniprot id: U3PD23
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS09185
gene id: 1389489:O159_RS09185
uniprot id: U3P889
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1389489:O159 RS08065
gene id: 1389489:O159_RS08065
uniprot id: U3PE18
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1389489:O159 RS00195
gene id: 1389489:O159_RS00195
uniprot id: U3P4G6
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS00930
gene id: 1389489:O159_RS00930
uniprot id: U3PAH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1389489:O159 RS10085
gene id: 1389489:O159_RS10085
uniprot id: U3P7C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpqB lipoprotein family.
messages: Cell membrane

1389489:O159 RS00815
gene id: 1389489:O159_RS00815
uniprot id: U3P4T0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1389489:O159 RS07375
gene id: 1389489:O159_RS07375
uniprot id: U3P9Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

1389489:O159 RS06735
gene id: 1389489:O159_RS06735
uniprot id: U3P9J6
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS10605
gene id: 1389489:O159_RS10605
uniprot id: U3P7N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1389489:O159 RS05940
gene id: 1389489:O159_RS05940
uniprot id: U3PD08
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1389489:O159 RS06790
gene id: 1389489:O159_RS06790
uniprot id: U3P9K5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1389489:O159 RS08540
gene id: 1389489:O159_RS08540
uniprot id: U3PB06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1389489:O159 RS09125
gene id: 1389489:O159_RS09125
uniprot id: U3P926
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1389489:O159 RS00695
gene id: 1389489:O159_RS00695
uniprot id: U3P690
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS01215
gene id: 1389489:O159_RS01215
uniprot id: U3P441
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1389489:O159 RS07305
gene id: 1389489:O159_RS07305
uniprot id: U3PDM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

1389489:O159 RS08640
gene id: 1389489:O159_RS08640
uniprot id: U3PB23
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1389489:O159 RS10985
gene id: 1389489:O159_RS10985
uniprot id: U3P998
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1389489:O159 RS05655
gene id: 1389489:O159_RS05655
uniprot id: U3P799
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1389489:O159 RS10590
gene id: 1389489:O159_RS10590
uniprot id: U3PC28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1389489:O159 RS05515
gene id: 1389489:O159_RS05515
uniprot id: U3P8P5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1389489:O159 RS10740
gene id: 1389489:O159_RS10740
uniprot id: U3P940
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1389489:O159 RS12845
gene id: 1389489:O159_RS12845
uniprot id: U3PD76
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1389489:O159 RS11200
gene id: 1389489:O159_RS11200
uniprot id: U3P9D4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1389489:O159 RS12095
gene id: 1389489:O159_RS12095
uniprot id: U3P8J1
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS06925
gene id: 1389489:O159_RS06925
uniprot id: U3P7Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1389489:O159 RS13035
gene id: 1389489:O159_RS13035
uniprot id: U3P454
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS10615
gene id: 1389489:O159_RS10615
uniprot id: U3PC33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1389489:O159 RS06440
gene id: 1389489:O159_RS06440
uniprot id: U3PD93
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1389489:O159 RS05035
gene id: 1389489:O159_RS05035
uniprot id: U3P4H0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1389489:O159 RS01395
gene id: 1389489:O159_RS01395
uniprot id: U3P511
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1389489:O159 RS05135
gene id: 1389489:O159_RS05135
uniprot id: U3P4I6
names: Similarity
messages: Belongs to the intimin/invasin family.

1389489:O159 RS09490
gene id: 1389489:O159_RS09490
uniprot id: U3P987
names: Similarity
messages: Belongs to the peptidase C40 family.

1389489:O159 RS02225
gene id: 1389489:O159_RS02225
uniprot id: U3PB07
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1389489:O159 RS01965
gene id: 1389489:O159_RS01965
uniprot id: U3P4F7
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1389489:O159 RS11450
gene id: 1389489:O159_RS11450
uniprot id: U3P9H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

1389489:O159 RS02405
gene id: 1389489:O159_RS02405
uniprot id: U3P5J4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1389489:O159 RS09205
gene id: 1389489:O159_RS09205
uniprot id: U3P6V7
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1389489:O159 RS08245
gene id: 1389489:O159_RS08245
uniprot id: U3P8P2
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1389489:O159 RS11005
gene id: 1389489:O159_RS11005
uniprot id: U3P7Z0
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS05525
gene id: 1389489:O159_RS05525
uniprot id: U3P774
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1389489:O159 RS01450
gene id: 1389489:O159_RS01450
uniprot id: U3P517
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1389489:O159 RS04445
gene id: 1389489:O159_RS04445
uniprot id: U3P848
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1389489:O159 RS04600
gene id: 1389489:O159_RS04600
uniprot id: U3P6Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

1389489:O159 RS08000
gene id: 1389489:O159_RS08000
uniprot id: U3P644
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1389489:O159 RS07240
gene id: 1389489:O159_RS07240
uniprot id: U3P845
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1389489:O159 RS01825
gene id: 1389489:O159_RS01825
uniprot id: U3P2S3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1389489:O159 RS10490
gene id: 1389489:O159_RS10490
uniprot id: U3PC05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1389489:O159 RS04555
gene id: 1389489:O159_RS04555
uniprot id: U3P870
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1389489:O159 RS08630
gene id: 1389489:O159_RS08630
uniprot id: U3P6I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
messages: Cytoplasm

1389489:O159 RS05250
gene id: 1389489:O159_RS05250
uniprot id: U3PCL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1389489:O159 RS00505
gene id: 1389489:O159_RS00505
uniprot id: U3P269
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS08535
gene id: 1389489:O159_RS08535
uniprot id: U3P7W5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

1389489:O159 RS00085
gene id: 1389489:O159_RS00085
uniprot id: U3P3G7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1389489:O159 RS09845
gene id: 1389489:O159_RS09845
uniprot id: U3P9F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1389489:O159 RS11455
gene id: 1389489:O159_RS11455
uniprot id: U3PCJ9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1389489:O159 RS06530
gene id: 1389489:O159_RS06530
uniprot id: U3P7S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1389489:O159 RS08810
gene id: 1389489:O159_RS08810
uniprot id: U3PB52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1389489:O159 RS08365
gene id: 1389489:O159_RS08365
uniprot id: U3P6D3
names: Similarity
messages: Belongs to the ketopantoate reductase family.

1389489:O159 RS06450
gene id: 1389489:O159_RS06450
uniprot id: U3P5A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1389489:O159 RS01220
gene id: 1389489:O159_RS01220
uniprot id: U3P6G8
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1389489:O159 RS04515
gene id: 1389489:O159_RS04515
uniprot id: U3P5R1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1389489:O159 RS10725
gene id: 1389489:O159_RS10725
uniprot id: U3PC53
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1389489:O159 RS07075
gene id: 1389489:O159_RS07075
uniprot id: U3P9S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1389489:O159 RS03270
gene id: 1389489:O159_RS03270
uniprot id: U3P577
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1389489:O159 RS07855
gene id: 1389489:O159_RS07855
uniprot id: U3P7F1
names: Similarity
messages: Belongs to the HSP15 family.

1389489:O159 RS02380
gene id: 1389489:O159_RS02380
uniprot id: U3P5J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1389489:O159 RS02075
gene id: 1389489:O159_RS02075
uniprot id: U3PAY0
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

1389489:O159 RS02065
gene id: 1389489:O159_RS02065
uniprot id: U3P4H6
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS06350
gene id: 1389489:O159_RS06350
uniprot id: U3P7P5
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1389489:O159 RS03560
gene id: 1389489:O159_RS03560
uniprot id: U3P678
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1389489:O159 RS12420
gene id: 1389489:O159_RS12420
uniprot id: U3P8P3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1389489:O159 RS08690
gene id: 1389489:O159_RS08690
uniprot id: U3PED9
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1389489:O159 RS08585
gene id: 1389489:O159_RS08585
uniprot id: U3PB16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1389489:O159 RS01650
gene id: 1389489:O159_RS01650
uniprot id: U3P549
names: Similarity
messages: Belongs to the FPG family.

1389489:O159 RS10510
gene id: 1389489:O159_RS10510
uniprot id: U3P8Y6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1389489:O159 RS00020
gene id: 1389489:O159_RS00020
uniprot id: U3PA15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1389489:O159 RS11485
gene id: 1389489:O159_RS11485
uniprot id: U3PFQ0
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1389489:O159 RS09465
gene id: 1389489:O159_RS09465
uniprot id: U3P984
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1389489:O159 RS12425
gene id: 1389489:O159_RS12425
uniprot id: U3P9Y0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1389489:O159 RS12930
gene id: 1389489:O159_RS12930
uniprot id: U3PGD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1389489:O159 RS06405
gene id: 1389489:O159_RS06405
uniprot id: U3P6R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1389489:O159 RS01355
gene id: 1389489:O159_RS01355
uniprot id: U3P6J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1389489:O159 RS10175
gene id: 1389489:O159_RS10175
uniprot id: U3P7E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1389489:O159 RS10720
gene id: 1389489:O159_RS10720
uniprot id: U3P934
names: Similarity
messages: Belongs to the SsuE family.

1389489:O159 RS01835
gene id: 1389489:O159_RS01835
uniprot id: U3P6S6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1389489:O159 RS01565
gene id: 1389489:O159_RS01565
uniprot id: U3P6M6
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

1389489:O159 RS07020
gene id: 1389489:O159_RS07020
uniprot id: U3P706
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1389489:O159 RS10580
gene id: 1389489:O159_RS10580
uniprot id: U3P7M4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1389489:O159 RS07115
gene id: 1389489:O159_RS07115
uniprot id: U3P5N3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

1389489:O159 RS09190
gene id: 1389489:O159_RS09190
uniprot id: U3PBB6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS03340
gene id: 1389489:O159_RS03340
uniprot id: U3P3P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1389489:O159 RS11565
gene id: 1389489:O159_RS11565
uniprot id: U3PCL3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1389489:O159 RS11825
gene id: 1389489:O159_RS11825
uniprot id: U3PCQ4
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS12745
gene id: 1389489:O159_RS12745
uniprot id: U3PAY6
names: Similarity
messages: Belongs to the UPF0098 family.

1389489:O159 RS00610
gene id: 1389489:O159_RS00610
uniprot id: U3P4Q1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1389489:O159 RS02315
gene id: 1389489:O159_RS02315
uniprot id: U3P4L8
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1389489:O159 RS07430
gene id: 1389489:O159_RS07430
uniprot id: U3PA05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1389489:O159 RS02050
gene id: 1389489:O159_RS02050
uniprot id: U3PAX6
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1389489:O159 RS03095
gene id: 1389489:O159_RS03095
uniprot id: U3P7I0
names: Similarity
messages: Belongs to the peptidase C40 family.

1389489:O159 RS08740
gene id: 1389489:O159_RS08740
uniprot id: U3PEE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1389489:O159 RS07275
gene id: 1389489:O159_RS07275
uniprot id: U3P744
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS04450
gene id: 1389489:O159_RS04450
uniprot id: U3PC70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1389489:O159 RS05215
gene id: 1389489:O159_RS05215
uniprot id: U3P616
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1389489:O159 RS02505
gene id: 1389489:O159_RS02505
uniprot id: U3P5L9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1389489:O159 RS02080
gene id: 1389489:O159_RS02080
uniprot id: U3P5C5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1389489:O159 RS05225
gene id: 1389489:O159_RS05225
uniprot id: U3PCK4
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1389489:O159 RS03230
gene id: 1389489:O159_RS03230
uniprot id: U3P630
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1389489:O159 RS04595
gene id: 1389489:O159_RS04595
uniprot id: U3PC87
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1389489:O159 RS12925
gene id: 1389489:O159_RS12925
uniprot id: U3PD92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1389489:O159 RS01505
gene id: 1389489:O159_RS01505
uniprot id: U3P2M2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1389489:O159 RS01525
gene id: 1389489:O159_RS01525
uniprot id: U3P530
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1389489:O159 RS05185
gene id: 1389489:O159_RS05185
uniprot id: U3P4J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1389489:O159 RS08605
gene id: 1389489:O159_RS08605
uniprot id: U3P6H5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1389489:O159 RS08980
gene id: 1389489:O159_RS08980
uniprot id: U3PEH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1389489:O159 RS10620
gene id: 1389489:O159_RS10620
uniprot id: U3PF89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1389489:O159 RS04855
gene id: 1389489:O159_RS04855
uniprot id: U3P8C6
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS02625
gene id: 1389489:O159_RS02625
uniprot id: U3P379
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1389489:O159 RS06935
gene id: 1389489:O159_RS06935
uniprot id: U3P6Z1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1389489:O159 RS06430
gene id: 1389489:O159_RS06430
uniprot id: U3P6R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1389489:O159 RS06880
gene id: 1389489:O159_RS06880
uniprot id: U3P5I6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1389489:O159 RS04080
gene id: 1389489:O159_RS04080
uniprot id: U3P6F9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1389489:O159 RS11820
gene id: 1389489:O159_RS11820
uniprot id: U3P9N6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1389489:O159 RS06260
gene id: 1389489:O159_RS06260
uniprot id: U3P574
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1389489:O159 RS03730
gene id: 1389489:O159_RS03730
uniprot id: U3PBW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1389489:O159 RS10890
gene id: 1389489:O159_RS10890
uniprot id: U3PCA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1389489:O159 RS01960
gene id: 1389489:O159_RS01960
uniprot id: U3P2U0
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1389489:O159 RS02990
gene id: 1389489:O159_RS02990
uniprot id: U3P4Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1389489:O159 RS13515
gene id: 1389489:O159_RS13515
uniprot id: U3PD13
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS05705
gene id: 1389489:O159_RS05705
uniprot id: U3P7A8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1389489:O159 RS10395
gene id: 1389489:O159_RS10395
uniprot id: U3PF48
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1389489:O159 RS08635
gene id: 1389489:O159_RS08635
uniprot id: U3P7Y1
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1389489:O159 RS04110
gene id: 1389489:O159_RS04110
uniprot id: U3P6G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1389489:O159 RS10695
gene id: 1389489:O159_RS10695
uniprot id: U3PC48
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS01445
gene id: 1389489:O159_RS01445
uniprot id: U3PAN4
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS00975
gene id: 1389489:O159_RS00975
uniprot id: U3P6D2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS05305
gene id: 1389489:O159_RS05305
uniprot id: U3P732
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1389489:O159 RS10570
gene id: 1389489:O159_RS10570
uniprot id: U3PF81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1389489:O159 RS08700
gene id: 1389489:O159_RS08700
uniprot id: U3P6J3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1389489:O159 RS10555
gene id: 1389489:O159_RS10555
uniprot id: U3P7L9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1389489:O159 RS10525
gene id: 1389489:O159_RS10525
uniprot id: U3P9U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1389489:O159 RS07840
gene id: 1389489:O159_RS07840
uniprot id: U3PDX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1389489:O159 RS05495
gene id: 1389489:O159_RS05495
uniprot id: U3PCQ5
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1389489:O159 RS08090
gene id: 1389489:O159_RS08090
uniprot id: U3PE22
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS03470
gene id: 1389489:O159_RS03470
uniprot id: U3P3R1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1389489:O159 RS07995
gene id: 1389489:O159_RS07995
uniprot id: U3P8J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1389489:O159 RS02015
gene id: 1389489:O159_RS02015
uniprot id: U3P4G7
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1389489:O159 RS10030
gene id: 1389489:O159_RS10030
uniprot id: U3PEY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1389489:O159 RS04565
gene id: 1389489:O159_RS04565
uniprot id: U3P6P7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1389489:O159 RS10170
gene id: 1389489:O159_RS10170
uniprot id: U3P9M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1389489:O159 RS05270
gene id: 1389489:O159_RS05270
uniprot id: U3P8K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1389489:O159 RS01830
gene id: 1389489:O159_RS01830
uniprot id: U3P4D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1389489:O159 RS05385
gene id: 1389489:O159_RS05385
uniprot id: U3P4N3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1389489:O159 RS01145
gene id: 1389489:O159_RS01145
uniprot id: U3P2G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1389489:O159 RS02865
gene id: 1389489:O159_RS02865
uniprot id: U3P7B4
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.
messages: Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.
messages: Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS05055
gene id: 1389489:O159_RS05055
uniprot id: U3P6Y9
names: Similarity
messages: Belongs to the SufE family.

1389489:O159 RS11520
gene id: 1389489:O159_RS11520
uniprot id: U3P9J0
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1389489:O159 RS11515
gene id: 1389489:O159_RS11515
uniprot id: U3P882
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

1389489:O159 RS06820
gene id: 1389489:O159_RS06820
uniprot id: U3PDE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1389489:O159 RS06415
gene id: 1389489:O159_RS06415
uniprot id: U3PD89
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1389489:O159 RS01110
gene id: 1389489:O159_RS01110
uniprot id: U3P4X3
names: Similarity
messages: Belongs to the catalase family.

1389489:O159 RS01630
gene id: 1389489:O159_RS01630
uniprot id: U3P2P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1389489:O159 RS12805
gene id: 1389489:O159_RS12805
uniprot id: U3PA37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1389489:O159 RS08020
gene id: 1389489:O159_RS08020
uniprot id: U3P8J9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1389489:O159 RS05675
gene id: 1389489:O159_RS05675
uniprot id: U3PCU4
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1389489:O159 RS09555
gene id: 1389489:O159_RS09555
uniprot id: U3PEQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1389489:O159 RS07340
gene id: 1389489:O159_RS07340
uniprot id: U3P5S0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1389489:O159 RS01870
gene id: 1389489:O159_RS01870
uniprot id: U3P6S9
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS06435
gene id: 1389489:O159_RS06435
uniprot id: U3P9B6
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1389489:O159 RS06315
gene id: 1389489:O159_RS06315
uniprot id: U3P6P4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1389489:O159 RS04490
gene id: 1389489:O159_RS04490
uniprot id: U3P5Q6
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

1389489:O159 RS08160
gene id: 1389489:O159_RS08160
uniprot id: U3P7L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1389489:O159 RS09145
gene id: 1389489:O159_RS09145
uniprot id: U3PEJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1389489:O159 RS04470
gene id: 1389489:O159_RS04470
uniprot id: U3P853
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1389489:O159 RS00370
gene id: 1389489:O159_RS00370
uniprot id: U3P3N6
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

1389489:O159 RS02530
gene id: 1389489:O159_RS02530
uniprot id: U3P364
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1389489:O159 RS04320
gene id: 1389489:O159_RS04320
uniprot id: U3P5N0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1389489:O159 RS05155
gene id: 1389489:O159_RS05155
uniprot id: U3P704
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS08550
gene id: 1389489:O159_RS08550
uniprot id: U3P8U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1389489:O159 RS12590
gene id: 1389489:O159_RS12590
uniprot id: U3PA08
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS01090
gene id: 1389489:O159_RS01090
uniprot id: U3P425
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1389489:O159 RS12195
gene id: 1389489:O159_RS12195
uniprot id: U3P8K7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1389489:O159 RS07140
gene id: 1389489:O159_RS07140
uniprot id: U3P5N8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1389489:O159 RS08165
gene id: 1389489:O159_RS08165
uniprot id: U3PAM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1389489:O159 RS12645
gene id: 1389489:O159_RS12645
uniprot id: U3P8S5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1389489:O159 RS05760
gene id: 1389489:O159_RS05760
uniprot id: U3P4X6
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1389489:O159 RS07495
gene id: 1389489:O159_RS07495
uniprot id: U3P5U8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1389489:O159 RS05210
gene id: 1389489:O159_RS05210
uniprot id: U3P4K0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1389489:O159 RS05180
gene id: 1389489:O159_RS05180
uniprot id: U3P709
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1389489:O159 RS05710
gene id: 1389489:O159_RS05710
uniprot id: U3P4V1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS05690
gene id: 1389489:O159_RS05690
uniprot id: U3P6B1
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1389489:O159 RS09600
gene id: 1389489:O159_RS09600
uniprot id: U3P8G9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1389489:O159 RS06975
gene id: 1389489:O159_RS06975
uniprot id: U3P9Q4
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1389489:O159 RS03715
gene id: 1389489:O159_RS03715
uniprot id: U3P5E7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1389489:O159 RS03265
gene id: 1389489:O159_RS03265
uniprot id: U3P3N0
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1389489:O159 RS04680
gene id: 1389489:O159_RS04680
uniprot id: U3PC98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1389489:O159 RS02280
gene id: 1389489:O159_RS02280
uniprot id: U3P5G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1389489:O159 RS10785
gene id: 1389489:O159_RS10785
uniprot id: U3P7R9
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1389489:O159 RS09945
gene id: 1389489:O159_RS09945
uniprot id: U3P7A4
names: Similarity
messages: Belongs to the UPF0045 family.

1389489:O159 RS12160
gene id: 1389489:O159_RS12160
uniprot id: U3PAN9
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS06120
gene id: 1389489:O159_RS06120
uniprot id: U3P552
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1389489:O159 RS04260
gene id: 1389489:O159_RS04260
uniprot id: U3P816
names: Similarity
messages: Belongs to the carbamate kinase family.

1389489:O159 RS10460
gene id: 1389489:O159_RS10460
uniprot id: U3P8X2
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1389489:O159 RS12800
gene id: 1389489:O159_RS12800
uniprot id: U3P8V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1389489:O159 RS02880
gene id: 1389489:O159_RS02880
uniprot id: U3P3D0
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1389489:O159 RS06965
gene id: 1389489:O159_RS06965
uniprot id: U3P5K2
names: Similarity
messages: Belongs to the Dps family.

1389489:O159 RS02320
gene id: 1389489:O159_RS02320
uniprot id: U3P713
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1389489:O159 RS07335
gene id: 1389489:O159_RS07335
uniprot id: U3P867
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1389489:O159 RS05820
gene id: 1389489:O159_RS05820
uniprot id: U3P8X3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS04525
gene id: 1389489:O159_RS04525
uniprot id: U3PC79
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS07345
gene id: 1389489:O159_RS07345
uniprot id: U3P758
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1389489:O159 RS07220
gene id: 1389489:O159_RS07220
uniprot id: U3P5Q2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1389489:O159 RS02385
gene id: 1389489:O159_RS02385
uniprot id: U3P334
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1389489:O159 RS08080
gene id: 1389489:O159_RS08080
uniprot id: U3P7J8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1389489:O159 RS06475
gene id: 1389489:O159_RS06475
uniprot id: U3P5B2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1389489:O159 RS10140
gene id: 1389489:O159_RS10140
uniprot id: U3PF01
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1389489:O159 RS06095
gene id: 1389489:O159_RS06095
uniprot id: U3P547
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1389489:O159 RS02230
gene id: 1389489:O159_RS02230
uniprot id: U3P5F6
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

1389489:O159 RS12000
gene id: 1389489:O159_RS12000
uniprot id: U3PCS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1389489:O159 RS11480
gene id: 1389489:O159_RS11480
uniprot id: U3PCK2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1389489:O159 RS08055
gene id: 1389489:O159_RS08055
uniprot id: U3P7J2
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1389489:O159 RS04370
gene id: 1389489:O159_RS04370
uniprot id: U3P6L3
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1389489:O159 RS09900
gene id: 1389489:O159_RS09900
uniprot id: U3P793
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS08915
gene id: 1389489:O159_RS08915
uniprot id: U3PB76
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1389489:O159 RS05005
gene id: 1389489:O159_RS05005
uniprot id: U3P4G4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1389489:O159 RS01530
gene id: 1389489:O159_RS01530
uniprot id: U3P2M7
names: Similarity
messages: Belongs to the peptidase C40 family.

1389489:O159 RS07050
gene id: 1389489:O159_RS07050
uniprot id: U3P9S1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1389489:O159 RS05685
gene id: 1389489:O159_RS05685
uniprot id: U3P4U7
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1389489:O159 RS06525
gene id: 1389489:O159_RS06525
uniprot id: U3PDA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1389489:O159 RS04435
gene id: 1389489:O159_RS04435
uniprot id: U3P466
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1389489:O159 RS07420
gene id: 1389489:O159_RS07420
uniprot id: U3P5T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1389489:O159 RS10050
gene id: 1389489:O159_RS10050
uniprot id: U3PBT4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1389489:O159 RS04635
gene id: 1389489:O159_RS04635
uniprot id: U3P6Q8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1389489:O159 RS12415
gene id: 1389489:O159_RS12415
uniprot id: U3PAT0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1389489:O159 RS03390
gene id: 1389489:O159_RS03390
uniprot id: U3P598
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1389489:O159 RS08030
gene id: 1389489:O159_RS08030
uniprot id: U3P7I8
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1389489:O159 RS09955
gene id: 1389489:O159_RS09955
uniprot id: U3PBR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

1389489:O159 RS08135
gene id: 1389489:O159_RS08135
uniprot id: U3P7L1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1389489:O159 RS03155
gene id: 1389489:O159_RS03155
uniprot id: U3P3L4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1389489:O159 RS12140
gene id: 1389489:O159_RS12140
uniprot id: U3P8K0
names: Similarity
messages: Belongs to the GARS family.

1389489:O159 RS00920
gene id: 1389489:O159_RS00920
uniprot id: U3P401
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1389489:O159 RS11550
gene id: 1389489:O159_RS11550
uniprot id: U3PAE5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1389489:O159 RS09620
gene id: 1389489:O159_RS09620
uniprot id: U3P751
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1389489:O159 RS04510
gene id: 1389489:O159_RS04510
uniprot id: U3P477
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1389489:O159 RS03425
gene id: 1389489:O159_RS03425
uniprot id: U3P7N8
names: Similarity
messages: Belongs to the ketopantoate reductase family.

1389489:O159 RS10485
gene id: 1389489:O159_RS10485
uniprot id: U3P8X8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1389489:O159 RS03055
gene id: 1389489:O159_RS03055
uniprot id: U3P5Y9
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

1389489:O159 RS07005
gene id: 1389489:O159_RS07005
uniprot id: U3PDH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1389489:O159 RS10520
gene id: 1389489:O159_RS10520
uniprot id: U3PF71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1389489:O159 RS09300
gene id: 1389489:O159_RS09300
uniprot id: U3P959
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1389489:O159 RS04800
gene id: 1389489:O159_RS04800
uniprot id: U3P5V3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1389489:O159 RS06195
gene id: 1389489:O159_RS06195
uniprot id: U3P7L7
names: Similarity
messages: Belongs to the thiolase-like superfamily. FabH family.

1389489:O159 RS06070
gene id: 1389489:O159_RS06070
uniprot id: U3PD29
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1389489:O159 RS07365
gene id: 1389489:O159_RS07365
uniprot id: U3P5S4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1389489:O159 RS04675
gene id: 1389489:O159_RS04675
uniprot id: U3P890
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1389489:O159 RS03195
gene id: 1389489:O159_RS03195
uniprot id: U3P7K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1389489:O159 RS12025
gene id: 1389489:O159_RS12025
uniprot id: U3PFY9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

1389489:O159 RS12090
gene id: 1389489:O159_RS12090
uniprot id: U3PAM6
names: Subcellular Location Annotation
messages: Cytoplasm

1389489:O159 RS04645
gene id: 1389489:O159_RS04645
uniprot id: U3P5S6
names: Similarity
messages: Belongs to the UPF0102 family.

1389489:O159 RS10775
gene id: 1389489:O159_RS10775
uniprot id: U3PFC1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS02795
gene id: 1389489:O159_RS02795
uniprot id: U3P5R9
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

1389489:O159 RS07035
gene id: 1389489:O159_RS07035
uniprot id: U3P807
names: Function
names: Subcellular Location Annotation
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

1389489:O159 RS05265
gene id: 1389489:O159_RS05265
uniprot id: U3P624
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1389489:O159 RS10980
gene id: 1389489:O159_RS10980
uniprot id: U3P7Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1389489:O159 RS05335
gene id: 1389489:O159_RS05335
uniprot id: U3P4M5
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1389489:O159 RS12440
gene id: 1389489:O159_RS12440
uniprot id: U3PAT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1389489:O159 RS02425
gene id: 1389489:O159_RS02425
uniprot id: U3PB53
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1389489:O159 RS00845
gene id: 1389489:O159_RS00845
uniprot id: U3P6B3
names: Similarity
messages: Belongs to the group II decarboxylase family.

1389489:O159 RS05000
gene id: 1389489:O159_RS05000
uniprot id: U3P6Y0
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1389489:O159 RS11885
gene id: 1389489:O159_RS11885
uniprot id: U3P9P4
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS10595
gene id: 1389489:O159_RS10595
uniprot id: U3PF85
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1389489:O159 RS08800
gene id: 1389489:O159_RS08800
uniprot id: U3P6L4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1389489:O159 RS05555
gene id: 1389489:O159_RS05555
uniprot id: U3P4R6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1389489:O159 RS06300
gene id: 1389489:O159_RS06300
uniprot id: U3PD70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1389489:O159 RS10070
gene id: 1389489:O159_RS10070
uniprot id: U3PBT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1389489:O159 RS12585
gene id: 1389489:O159_RS12585
uniprot id: U3P8R7
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1389489:O159 RS07380
gene id: 1389489:O159_RS07380
uniprot id: U3PDN4
names: Similarity
messages: Belongs to the YggT family.

1389489:O159 RS12750
gene id: 1389489:O159_RS12750
uniprot id: U3P8U4
names: Similarity
messages: Belongs to the PrpD family.

1389489:O159 RS10545
gene id: 1389489:O159_RS10545
uniprot id: U3PF75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1389489:O159 RS10610
gene id: 1389489:O159_RS10610
uniprot id: U3P912
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1389489:O159 RS00205
gene id: 1389489:O159_RS00205
uniprot id: U3P3I6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS07180
gene id: 1389489:O159_RS07180
uniprot id: U3P726
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS01755
gene id: 1389489:O159_RS01755
uniprot id: U3P572
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1389489:O159 RS04085
gene id: 1389489:O159_RS04085
uniprot id: U3P412
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1389489:O159 RS06355
gene id: 1389489:O159_RS06355
uniprot id: U3P592
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1389489:O159 RS07465
gene id: 1389489:O159_RS07465
uniprot id: U3P892
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1389489:O159 RS02975
gene id: 1389489:O159_RS02975
uniprot id: U3P7C9
names: Subcellular Location Annotation
messages: Cytoplasm

1389489:O159 RS06605
gene id: 1389489:O159_RS06605
uniprot id: U3PDB5
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS13325
gene id: 1389489:O159_RS13325
uniprot id: U3P8B0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS07890
gene id: 1389489:O159_RS07890
uniprot id: U3P8H7
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS03345
gene id: 1389489:O159_RS03345
uniprot id: U3P590
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

1389489:O159 RS04720
gene id: 1389489:O159_RS04720
uniprot id: U3P5U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1389489:O159 RS12900
gene id: 1389489:O159_RS12900
uniprot id: U3PD88
names: Similarity
messages: Belongs to the ParB family.

1389489:O159 RS01975
gene id: 1389489:O159_RS01975
uniprot id: U3PAW4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS10130
gene id: 1389489:O159_RS10130
uniprot id: U3P7D3
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS12435
gene id: 1389489:O159_RS12435
uniprot id: U3PG54
names: Similarity
messages: Belongs to the Fur family.

1389489:O159 RS12735
gene id: 1389489:O159_RS12735
uniprot id: U3PD59
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1389489:O159 RS05375
gene id: 1389489:O159_RS05375
uniprot id: U3PCN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1389489:O159 RS11675
gene id: 1389489:O159_RS11675
uniprot id: U3PAG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1389489:O159 RS08190
gene id: 1389489:O159_RS08190
uniprot id: U3PE39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1389489:O159 RS09970
gene id: 1389489:O159_RS09970
uniprot id: U3P8N9
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS02710
gene id: 1389489:O159_RS02710
uniprot id: U3PBB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1389489:O159 RS00420
gene id: 1389489:O159_RS00420
uniprot id: U3P647
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

1389489:O159 RS00840
gene id: 1389489:O159_RS00840
uniprot id: U3P3Y7
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS08610
gene id: 1389489:O159_RS08610
uniprot id: U3P7X7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1389489:O159 RS09820
gene id: 1389489:O159_RS09820
uniprot id: U3P9F0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1389489:O159 RS00100
gene id: 1389489:O159_RS00100
uniprot id: U3P4E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

1389489:O159 RS05360
gene id: 1389489:O159_RS05360
uniprot id: U3P4M9
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS00925
gene id: 1389489:O159_RS00925
uniprot id: U3P6C3
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS11185
gene id: 1389489:O159_RS11185
uniprot id: U3PA90
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Belongs to the acyl-CoA oxidase family.

1389489:O159 RS01420
gene id: 1389489:O159_RS01420
uniprot id: U3PAN1
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1389489:O159 RS06410
gene id: 1389489:O159_RS06410
uniprot id: U3P9B1
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS08095
gene id: 1389489:O159_RS08095
uniprot id: U3P8L1
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

1389489:O159 RS04075
gene id: 1389489:O159_RS04075
uniprot id: U3PC12
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1389489:O159 RS01120
gene id: 1389489:O159_RS01120
uniprot id: U3P431
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS02815
gene id: 1389489:O159_RS02815
uniprot id: U3PBE2
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1389489:O159 RS12250
gene id: 1389489:O159_RS12250
uniprot id: U3PCX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

1389489:O159 RS03950
gene id: 1389489:O159_RS03950
uniprot id: U3P5I0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1389489:O159 RS10895
gene id: 1389489:O159_RS10895
uniprot id: U3PFG6
names: Similarity
messages: Belongs to the thioredoxin family.

1389489:O159 RS09535
gene id: 1389489:O159_RS09535
uniprot id: U3P996
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1389489:O159 RS10560
gene id: 1389489:O159_RS10560
uniprot id: U3P8Z8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1389489:O159 RS07030
gene id: 1389489:O159_RS07030
uniprot id: U3PDI1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1389489:O159 RS02525
gene id: 1389489:O159_RS02525
uniprot id: U3P5M4
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1389489:O159 RS09705
gene id: 1389489:O159_RS09705
uniprot id: U3P8I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1389489:O159 RS05715
gene id: 1389489:O159_RS05715
uniprot id: U3P6B4
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1389489:O159 RS05520
gene id: 1389489:O159_RS05520
uniprot id: U3PCR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1389489:O159 RS02000
gene id: 1389489:O159_RS02000
uniprot id: U3PAW9
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS01330
gene id: 1389489:O159_RS01330
uniprot id: U3P501
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1389489:O159 RS05175
gene id: 1389489:O159_RS05175
uniprot id: U3PCJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1389489:O159 RS06970
gene id: 1389489:O159_RS06970
uniprot id: U3P6Z6
names: Similarity
messages: Belongs to the FPG family.

1389489:O159 RS09210
gene id: 1389489:O159_RS09210
uniprot id: U3P895
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1389489:O159 RS01740
gene id: 1389489:O159_RS01740
uniprot id: U3P2Q9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1389489:O159 RS09765
gene id: 1389489:O159_RS09765
uniprot id: U3P9D9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1389489:O159 RS05390
gene id: 1389489:O159_RS05390
uniprot id: U3P648
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS02460
gene id: 1389489:O159_RS02460
uniprot id: U3P349
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1389489:O159 RS06180
gene id: 1389489:O159_RS06180
uniprot id: U3P6M4
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1389489:O159 RS09200
gene id: 1389489:O159_RS09200
uniprot id: U3P941
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1389489:O159 RS00230
gene id: 1389489:O159_RS00230
uniprot id: U3P3J1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1389489:O159 RS09650
gene id: 1389489:O159_RS09650
uniprot id: U3P8H5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS02810
gene id: 1389489:O159_RS02810
uniprot id: U3P7A6
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS04045
gene id: 1389489:O159_RS04045
uniprot id: U3P7X8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1389489:O159 RS07170
gene id: 1389489:O159_RS07170
uniprot id: U3P833
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1389489:O159 RS05740
gene id: 1389489:O159_RS05740
uniprot id: U3P6B7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1389489:O159 RS04020
gene id: 1389489:O159_RS04020
uniprot id: U3P7X3
names: Similarity
messages: Belongs to the peptidase S1C family.

1389489:O159 RS06800
gene id: 1389489:O159_RS06800
uniprot id: U3P7X1
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1389489:O159 RS10505
gene id: 1389489:O159_RS10505
uniprot id: U3P7K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1389489:O159 RS09245
gene id: 1389489:O159_RS09245
uniprot id: U3P8A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1389489:O159 RS05165
gene id: 1389489:O159_RS05165
uniprot id: U3P606
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxine kinase family. PdxY subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.

1389489:O159 RS00380
gene id: 1389489:O159_RS00380
uniprot id: U3PA84
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS02885
gene id: 1389489:O159_RS02885
uniprot id: U3P4X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1389489:O159 RS05200
gene id: 1389489:O159_RS05200
uniprot id: U3PCJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1389489:O159 RS11940
gene id: 1389489:O159_RS11940
uniprot id: U3PCR8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1389489:O159 RS09590
gene id: 1389489:O159_RS09590
uniprot id: U3P9A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1389489:O159 RS10540
gene id: 1389489:O159_RS10540
uniprot id: U3PC16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1389489:O159 RS03090
gene id: 1389489:O159_RS03090
uniprot id: U3P545
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1389489:O159 RS10825
gene id: 1389489:O159_RS10825
uniprot id: U3PFE2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1389489:O159 RS01455
gene id: 1389489:O159_RS01455
uniprot id: U3P2L3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1389489:O159 RS04480
gene id: 1389489:O159_RS04480
uniprot id: U3P6N0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1389489:O159 RS09135
gene id: 1389489:O159_RS09135
uniprot id: U3P880
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1389489:O159 RS10585
gene id: 1389489:O159_RS10585
uniprot id: U3P906
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1389489:O159 RS05650
gene id: 1389489:O159_RS05650
uniprot id: U3PCT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1389489:O159 RS08075
gene id: 1389489:O159_RS08075
uniprot id: U3P662
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS01490
gene id: 1389489:O159_RS01490
uniprot id: U3P6L2
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1389489:O159 RS07515
gene id: 1389489:O159_RS07515
uniprot id: U3P8A1
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1389489:O159 RS08945
gene id: 1389489:O159_RS08945
uniprot id: U3PEH4
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

1389489:O159 RS11845
gene id: 1389489:O159_RS11845
uniprot id: U3P9N8
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS08355
gene id: 1389489:O159_RS08355
uniprot id: U3PE92
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1389489:O159 RS04955
gene id: 1389489:O159_RS04955
uniprot id: U3P4F4
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

1389489:O159 RS02205
gene id: 1389489:O159_RS02205
uniprot id: U3P5F0
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1389489:O159 RS09030
gene id: 1389489:O159_RS09030
uniprot id: U3P913
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1389489:O159 RS03335
gene id: 1389489:O159_RS03335
uniprot id: U3P645
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1389489:O159 RS10780
gene id: 1389489:O159_RS10780
uniprot id: U3PA11
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

1389489:O159 RS09220
gene id: 1389489:O159_RS09220
uniprot id: U3PEK6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1389489:O159 RS11690
gene id: 1389489:O159_RS11690
uniprot id: U3P8B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1389489:O159 RS05130
gene id: 1389489:O159_RS05130
uniprot id: U3P700
names: Similarity
messages: Belongs to the intimin/invasin family.

1389489:O159 RS07895
gene id: 1389489:O159_RS07895
uniprot id: U3P623
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS10005
gene id: 1389489:O159_RS10005
uniprot id: U3PEY0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1389489:O159 RS04505
gene id: 1389489:O159_RS04505
uniprot id: U3P6N8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1389489:O159 RS02580
gene id: 1389489:O159_RS02580
uniprot id: U3PB90
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1389489:O159 RS03485
gene id: 1389489:O159_RS03485
uniprot id: U3PBT2
names: Similarity
messages: Belongs to the ribF family.

1389489:O159 RS05075
gene id: 1389489:O159_RS05075
uniprot id: U3PCH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

1389489:O159 RS04115
gene id: 1389489:O159_RS04115
uniprot id: U3P416
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1389489:O159 RS10075
gene id: 1389489:O159_RS10075
uniprot id: U3PEZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1389489:O159 RS00030
gene id: 1389489:O159_RS00030
uniprot id: U3P1U7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1389489:O159 RS07385
gene id: 1389489:O159_RS07385
uniprot id: U3P877
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1389489:O159 RS02650
gene id: 1389489:O159_RS02650
uniprot id: U3P384
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1389489:O159 RS01210
gene id: 1389489:O159_RS01210
uniprot id: U3P2H2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1389489:O159 RS06850
gene id: 1389489:O159_RS06850
uniprot id: U3P7Y0
names: Similarity
messages: Belongs to the NDK family.

1389489:O159 RS03800
gene id: 1389489:O159_RS03800
uniprot id: U3P5G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1389489:O159 RS05735
gene id: 1389489:O159_RS05735
uniprot id: U3P4V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1389489:O159 RS05930
gene id: 1389489:O159_RS05930
uniprot id: U3P6I6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1389489:O159 RS05505
gene id: 1389489:O159_RS05505
uniprot id: U3P4Q4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1389489:O159 RS01030
gene id: 1389489:O159_RS01030
uniprot id: U3PAI4
names: Similarity
messages: Belongs to the UPF0234 family.

1389489:O159 RS06565
gene id: 1389489:O159_RS06565
uniprot id: U3P5C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1389489:O159 RS07455
gene id: 1389489:O159_RS07455
uniprot id: U3PA10
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1389489:O159 RS02435
gene id: 1389489:O159_RS02435
uniprot id: U3P345
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

1389489:O159 RS09725
gene id: 1389489:O159_RS09725
uniprot id: U3P764
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1389489:O159 RS12935
gene id: 1389489:O159_RS12935
uniprot id: U3PB21
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1389489:O159 RS10745
gene id: 1389489:O159_RS10745
uniprot id: U3PC59
names: Similarity
messages: Belongs to the thymidine kinase family.

1389489:O159 RS04615
gene id: 1389489:O159_RS04615
uniprot id: U3P5S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1389489:O159 RS05680
gene id: 1389489:O159_RS05680
uniprot id: U3P7A3
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1389489:O159 RS12860
gene id: 1389489:O159_RS12860
uniprot id: U3P8V9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1389489:O159 RS07150
gene id: 1389489:O159_RS07150
uniprot id: U3P9U4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1389489:O159 RS09560
gene id: 1389489:O159_RS09560
uniprot id: U3P999
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1389489:O159 RS10450
gene id: 1389489:O159_RS10450
uniprot id: U3P9T1
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS06845
gene id: 1389489:O159_RS06845
uniprot id: U3PDF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

1389489:O159 RS01620
gene id: 1389489:O159_RS01620
uniprot id: U3PAR5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1389489:O159 RS07425
gene id: 1389489:O159_RS07425
uniprot id: U3P778
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1389489:O159 RS07290
gene id: 1389489:O159_RS07290
uniprot id: U3P856
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

1389489:O159 RS03005
gene id: 1389489:O159_RS03005
uniprot id: U3P5W6
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1389489:O159 RS04995
gene id: 1389489:O159_RS04995
uniprot id: U3PCF9
names: Subcellular Location Annotation
messages: Cell membrane

1389489:O159 RS09730
gene id: 1389489:O159_RS09730
uniprot id: U3P8I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1389489:O159 RS04685
gene id: 1389489:O159_RS04685
uniprot id: U3P6R9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS08060
gene id: 1389489:O159_RS08060
uniprot id: U3PAG6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1389489:O159 RS02825
gene id: 1389489:O159_RS02825
uniprot id: U3P3B8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1389489:O159 RS05745
gene id: 1389489:O159_RS05745
uniprot id: U3P8T6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1389489:O159 RS12005
gene id: 1389489:O159_RS12005
uniprot id: U3PFY4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1389489:O159 RS06915
gene id: 1389489:O159_RS06915
uniprot id: U3P9P1
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1389489:O159 RS06205
gene id: 1389489:O159_RS06205
uniprot id: U3P6M9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1389489:O159 RS07390
gene id: 1389489:O159_RS07390
uniprot id: U3P5S9
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1389489:O159 RS02010
gene id: 1389489:O159_RS02010
uniprot id: U3P2V3
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1389489:O159 RS01005
gene id: 1389489:O159_RS01005
uniprot id: U3PAI1
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1389489:O159 RS03550
gene id: 1389489:O159_RS03550
uniprot id: U3P7Q7
names: Similarity
messages: Belongs to the CsoR family.

1389489:O159 RS06635
gene id: 1389489:O159_RS06635
uniprot id: U3P7T9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1389489:O159 RS00510
gene id: 1389489:O159_RS00510
uniprot id: U3P666
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1389489:O159 RS04790
gene id: 1389489:O159_RS04790
uniprot id: U3P6T6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1389489:O159 RS08010
gene id: 1389489:O159_RS08010
uniprot id: U3PAE7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1389489:O159 RS08410
gene id: 1389489:O159_RS08410
uniprot id: U3P6E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1389489:O159 RS04090
gene id: 1389489:O159_RS04090
uniprot id: U3P5J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1389489:O159 RS04630
gene id: 1389489:O159_RS04630
uniprot id: U3PC92
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1389489:O159 RS00010
gene id: 1389489:O159_RS00010
uniprot id: U3P3F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1389489:O159 RS01360
gene id: 1389489:O159_RS01360
uniprot id: U3PAM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Mediates magnesium influx to the cytosol.

1389489:O159 RS08975
gene id: 1389489:O159_RS08975
uniprot id: U3PB82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1389489:O159 RS06305
gene id: 1389489:O159_RS06305
uniprot id: U3P7N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1389489:O159 RS11150
gene id: 1389489:O159_RS11150
uniprot id: U3PCE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1389489:O159 RS06875
gene id: 1389489:O159_RS06875
uniprot id: U3P7Y4
names: Subcellular Location Annotation
messages: Membrane

1389489:O159 RS03000
gene id: 1389489:O159_RS03000
uniprot id: U3PBH8
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1389489:O159 RS03910
gene id: 1389489:O159_RS03910
uniprot id: U3P3Y3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1389489:O159 RS11715
gene id: 1389489:O159_RS11715
uniprot id: U3P8B7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1389489:O159 RS00385
gene id: 1389489:O159_RS00385
uniprot id: U3P4M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1389489:O159 RS07370
gene id: 1389489:O159_RS07370
uniprot id: U3P765
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1389489:O159 RS00295
gene id: 1389489:O159_RS00295
uniprot id: U3PA56
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1389489:O159 RS06360
gene id: 1389489:O159_RS06360
uniprot id: U3P6Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1389489:O159 RS07360
gene id: 1389489:O159_RS07360
uniprot id: U3P873
names: Subcellular Location Annotation
messages: Cytoplasm

1389489:O159 RS08005
gene id: 1389489:O159_RS08005
uniprot id: U3P7I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1389489:O159 RS02275
gene id: 1389489:O159_RS02275
uniprot id: U3PB20
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1389489:O159 RS09585
gene id: 1389489:O159_RS09585
uniprot id: U3PER3
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1389489:O159 RS03070
gene id: 1389489:O159_RS03070
uniprot id: U3P7H4
names: Subcellular Location Annotation
messages: Cytoplasm

1389489:O159 RS07260
gene id: 1389489:O159_RS07260
uniprot id: U3PDL5
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

1389489:O159 RS05550
gene id: 1389489:O159_RS05550
uniprot id: U3P777
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1389489:O159 RS07435
gene id: 1389489:O159_RS07435
uniprot id: U3PDP1
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS03235
gene id: 1389489:O159_RS03235
uniprot id: U3P3M6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS12920
gene id: 1389489:O159_RS12920
uniprot id: U3PA54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1389489:O159 RS09750
gene id: 1389489:O159_RS09750
uniprot id: U3P769
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1389489:O159 RS04305
gene id: 1389489:O159_RS04305
uniprot id: U3PC43
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1389489:O159 RS02310
gene id: 1389489:O159_RS02310
uniprot id: U3P321
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1389489:O159 RS07505
gene id: 1389489:O159_RS07505
uniprot id: U3PA27
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1389489:O159 RS03600
gene id: 1389489:O159_RS03600
uniprot id: U3P7R5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1389489:O159 RS06825
gene id: 1389489:O159_RS06825
uniprot id: U3P7X6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1389489:O159 RS07280
gene id: 1389489:O159_RS07280
uniprot id: U3P9W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1389489:O159 RS08515
gene id: 1389489:O159_RS08515
uniprot id: U3PB05
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1389489:O159 RS01500
gene id: 1389489:O159_RS01500
uniprot id: U3P526
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1389489:O159 RS01590
gene id: 1389489:O159_RS01590
uniprot id: U3P6N1
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1389489:O159 RS05170
gene id: 1389489:O159_RS05170
uniprot id: U3P8I2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1389489:O159 RS03505
gene id: 1389489:O159_RS03505
uniprot id: U3PBT5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1389489:O159 RS10565
gene id: 1389489:O159_RS10565
uniprot id: U3PC22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1389489:O159 RS10470
gene id: 1389489:O159_RS10470
uniprot id: U3PF63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1389489:O159 RS08590
gene id: 1389489:O159_RS08590
uniprot id: U3PEC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane