1384459:GL4 RS15970
gene id: 1384459:GL4_RS15970
uniprot id: A0A0A8K9F3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1384459:GL4 RS06820
gene id: 1384459:GL4_RS06820
uniprot id: A0A0A8K2Z9
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1384459:GL4 RS00360
gene id: 1384459:GL4_RS00360
uniprot id: A0A0A8JXN3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1384459:GL4 RS08350
gene id: 1384459:GL4_RS08350
uniprot id: A0A0A8K2Z7
names: Similarity
messages: Belongs to the SfsA family.

1384459:GL4 RS13530
gene id: 1384459:GL4_RS13530
uniprot id: A0A0A8K6S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1384459:GL4 RS03875
gene id: 1384459:GL4_RS03875
uniprot id: A0A0A8K193
names: Similarity
messages: Belongs to the glutamate synthase family.

1384459:GL4 RS15625
gene id: 1384459:GL4_RS15625
uniprot id: A0A0A8K6S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1384459:GL4 RS15590
gene id: 1384459:GL4_RS15590
uniprot id: A0A0A8K764
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS11935
gene id: 1384459:GL4_RS11935
uniprot id: A0A0A8K4U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1384459:GL4 RS01640
gene id: 1384459:GL4_RS01640
uniprot id: A0A0A8JZ05
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1384459:GL4 RS04645
gene id: 1384459:GL4_RS04645
uniprot id: A0A0A8K367
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1384459:GL4 RS11375
gene id: 1384459:GL4_RS11375
uniprot id: A0A0A8K4R2
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

1384459:GL4 RS01985
gene id: 1384459:GL4_RS01985
uniprot id: A0A0A8K1N1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1384459:GL4 RS00370
gene id: 1384459:GL4_RS00370
uniprot id: A0A0A8JY80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1384459:GL4 RS11485
gene id: 1384459:GL4_RS11485
uniprot id: A0A0A8K4D9
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1384459:GL4 RS12625
gene id: 1384459:GL4_RS12625
uniprot id: A0A0A8K516
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1384459:GL4 RS09385
gene id: 1384459:GL4_RS09385
uniprot id: A0A0A8K5Z0
names: Similarity
messages: Belongs to the transglycosylase Slt family.
messages: Belongs to the virb1 family.

1384459:GL4 RS01305
gene id: 1384459:GL4_RS01305
uniprot id: A0A0A8JYR2
names: Similarity
messages: Belongs to the asparagine synthetase family.

1384459:GL4 RS07760
gene id: 1384459:GL4_RS07760
uniprot id: A0A0A8K4X4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1384459:GL4 RS09745
gene id: 1384459:GL4_RS09745
uniprot id: A0A0A8K632
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1384459:GL4 RS09060
gene id: 1384459:GL4_RS09060
uniprot id: A0A0A8K5Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0314 family.
messages: Cell membrane

1384459:GL4 RS08810
gene id: 1384459:GL4_RS08810
uniprot id: A0A0A8K417
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1384459:GL4 RS09475
gene id: 1384459:GL4_RS09475
uniprot id: A0A0A8K4G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1384459:GL4 RS11975
gene id: 1384459:GL4_RS11975
uniprot id: A0A0A8K7F2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1384459:GL4 RS08345
gene id: 1384459:GL4_RS08345
uniprot id: A0A0A8K2N6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1384459:GL4 RS09205
gene id: 1384459:GL4_RS09205
uniprot id: A0A0A8K4A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1384459:GL4 RS01755
gene id: 1384459:GL4_RS01755
uniprot id: A0A0A8JYE8
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS02015
gene id: 1384459:GL4_RS02015
uniprot id: A0A0A8JZB6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1384459:GL4 RS08615
gene id: 1384459:GL4_RS08615
uniprot id: A0A0A8K350
names: Similarity
messages: Belongs to the HisA/HisF family.

1384459:GL4 RS03770
gene id: 1384459:GL4_RS03770
uniprot id: A0A0A8K2M1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1384459:GL4 RS11050
gene id: 1384459:GL4_RS11050
uniprot id: A0A0A8K6V3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1384459:GL4 RS04820
gene id: 1384459:GL4_RS04820
uniprot id: A0A0A8K116
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1384459:GL4 RS13215
gene id: 1384459:GL4_RS13215
uniprot id: A0A0A8K5S8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1384459:GL4 RS06855
gene id: 1384459:GL4_RS06855
uniprot id: A0A0A8K4I2
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS04560
gene id: 1384459:GL4_RS04560
uniprot id: A0A0A8K0X7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1384459:GL4 RS01325
gene id: 1384459:GL4_RS01325
uniprot id: A0A0A8JYS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1384459:GL4 RS06230
gene id: 1384459:GL4_RS06230
uniprot id: A0A0A8K1A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1384459:GL4 RS05750
gene id: 1384459:GL4_RS05750
uniprot id: A0A0A8K147
names: Cofactor
messages: Binds 2 manganese ions per subunit.

1384459:GL4 RS07910
gene id: 1384459:GL4_RS07910
uniprot id: A0A0A8K3H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1384459:GL4 RS15930
gene id: 1384459:GL4_RS15930
uniprot id: A0A0A8K7B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1384459:GL4 RS02580
gene id: 1384459:GL4_RS02580
uniprot id: A0A0A8JZL0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1384459:GL4 RS03365
gene id: 1384459:GL4_RS03365
uniprot id: A0A0A8K041
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1384459:GL4 RS15090
gene id: 1384459:GL4_RS15090
uniprot id: A0A0A8K6Y1
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS08500
gene id: 1384459:GL4_RS08500
uniprot id: A0A0A8K2M9
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS10150
gene id: 1384459:GL4_RS10150
uniprot id: A0A0A8K427
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1384459:GL4 RS09230
gene id: 1384459:GL4_RS09230
uniprot id: A0A0A8K4C6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1384459:GL4 RS03940
gene id: 1384459:GL4_RS03940
uniprot id: A0A0A8K044
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1384459:GL4 RS15350
gene id: 1384459:GL4_RS15350
uniprot id: A0A0A8K966
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1384459:GL4 RS01620
gene id: 1384459:GL4_RS01620
uniprot id: A0A0A8JZF4
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1384459:GL4 RS09955
gene id: 1384459:GL4_RS09955
uniprot id: A0A0A8K665
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1384459:GL4 RS04855
gene id: 1384459:GL4_RS04855
uniprot id: A0A0A8K0H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1384459:GL4 RS05020
gene id: 1384459:GL4_RS05020
uniprot id: A0A0A8K0K3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1384459:GL4 RS01935
gene id: 1384459:GL4_RS01935
uniprot id: A0A0A8K1M3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1384459:GL4 RS02140
gene id: 1384459:GL4_RS02140
uniprot id: A0A0A8JZD4
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1384459:GL4 RS00200
gene id: 1384459:GL4_RS00200
uniprot id: A0A0A8JY55
names: Similarity
messages: Belongs to the DNA photolyase family.

1384459:GL4 RS13565
gene id: 1384459:GL4_RS13565
uniprot id: A0A0A8K8B7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1384459:GL4 RS00365
gene id: 1384459:GL4_RS00365
uniprot id: A0A0A8K0L5
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

1384459:GL4 RS00540
gene id: 1384459:GL4_RS00540
uniprot id: A0A0A8JYS4
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1384459:GL4 RS16410
gene id: 1384459:GL4_RS16410
uniprot id: A0A0A8K7A9
names: Similarity
messages: Belongs to the peptidase S11 family.

1384459:GL4 RS07460
gene id: 1384459:GL4_RS07460
uniprot id: A0A0A8K218
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide deacetylase family.
messages: Cytoplasm
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

1384459:GL4 RS01905
gene id: 1384459:GL4_RS01905
uniprot id: A0A0A8JZU9
names: Similarity
messages: Belongs to the asparagine synthetase family.

1384459:GL4 RS15225
gene id: 1384459:GL4_RS15225
uniprot id: A0A0A8K6I9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1384459:GL4 RS08310
gene id: 1384459:GL4_RS08310
uniprot id: A0A0A8K2I6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1384459:GL4 RS04425
gene id: 1384459:GL4_RS04425
uniprot id: A0A0A8K0G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1384459:GL4 RS04885
gene id: 1384459:GL4_RS04885
uniprot id: A0A0A8K3A5
names: Function
names: Similarity
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: May be required for disulfide bond formation in some proteins.

1384459:GL4 RS08785
gene id: 1384459:GL4_RS08785
uniprot id: A0A0A8K412
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1384459:GL4 RS00970
gene id: 1384459:GL4_RS00970
uniprot id: A0A0A8JZ98
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1384459:GL4 RS08800
gene id: 1384459:GL4_RS08800
uniprot id: A0A0A8K2X7
names: Similarity
messages: Belongs to the HesB/IscA family.

1384459:GL4 RS01895
gene id: 1384459:GL4_RS01895
uniprot id: A0A0A8JZ61
names: Similarity
messages: Belongs to the peptidase M42 family.

1384459:GL4 RS12600
gene id: 1384459:GL4_RS12600
uniprot id: A0A0A8K658
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1384459:GL4 RS05850
gene id: 1384459:GL4_RS05850
uniprot id: A0A0A8K1I1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1384459:GL4 RS14525
gene id: 1384459:GL4_RS14525
uniprot id: A0A0A8K8V9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1384459:GL4 RS08055
gene id: 1384459:GL4_RS08055
uniprot id: A0A0A8K2H4
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1384459:GL4 RS08060
gene id: 1384459:GL4_RS08060
uniprot id: A0A0A8K2V0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1384459:GL4 RS11230
gene id: 1384459:GL4_RS11230
uniprot id: A0A0A8K4C0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1384459:GL4 RS16075
gene id: 1384459:GL4_RS16075
uniprot id: A0A0A8K741
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

1384459:GL4 RS13335
gene id: 1384459:GL4_RS13335
uniprot id: A0A0A8K864
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

1384459:GL4 RS01035
gene id: 1384459:GL4_RS01035
uniprot id: A0A0A8JYJ6
names: Function
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.

1384459:GL4 RS09730
gene id: 1384459:GL4_RS09730
uniprot id: A0A0A8K3W3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1384459:GL4 RS08780
gene id: 1384459:GL4_RS08780
uniprot id: A0A0A8K383
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1384459:GL4 RS14725
gene id: 1384459:GL4_RS14725
uniprot id: A0A0A8K6D9
names: Subcellular Location Annotation
messages: Cytoplasm

1384459:GL4 RS12035
gene id: 1384459:GL4_RS12035
uniprot id: A0A0A8K589
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

1384459:GL4 RS10375
gene id: 1384459:GL4_RS10375
uniprot id: A0A0A8K4V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1384459:GL4 RS06675
gene id: 1384459:GL4_RS06675
uniprot id: A0A0A8K236
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1384459:GL4 RS13105
gene id: 1384459:GL4_RS13105
uniprot id: A0A0A8K5B1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1384459:GL4 RS13410
gene id: 1384459:GL4_RS13410
uniprot id: A0A0A8K882
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1384459:GL4 RS00550
gene id: 1384459:GL4_RS00550
uniprot id: A0A0A8JXR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1384459:GL4 RS15005
gene id: 1384459:GL4_RS15005
uniprot id: A0A0A8K923
names: Similarity
messages: Belongs to the pyruvate kinase family.

1384459:GL4 RS02350
gene id: 1384459:GL4_RS02350
uniprot id: A0A0A8JZG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1384459:GL4 RS04890
gene id: 1384459:GL4_RS04890
uniprot id: A0A0A8K0P7
names: Function
names: Similarity
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: May be required for disulfide bond formation in some proteins.

1384459:GL4 RS04340
gene id: 1384459:GL4_RS04340
uniprot id: A0A0A8K1K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

1384459:GL4 RS03335
gene id: 1384459:GL4_RS03335
uniprot id: A0A0A8JZY6
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1384459:GL4 RS01690
gene id: 1384459:GL4_RS01690
uniprot id: A0A0A8JZ20
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1384459:GL4 RS04630
gene id: 1384459:GL4_RS04630
uniprot id: A0A0A8K0Y7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1384459:GL4 RS15480
gene id: 1384459:GL4_RS15480
uniprot id: A0A0A8K7V3
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS07640
gene id: 1384459:GL4_RS07640
uniprot id: A0A0A8K4U7
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1384459:GL4 RS06020
gene id: 1384459:GL4_RS06020
uniprot id: A0A0A8K154
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1384459:GL4 RS02470
gene id: 1384459:GL4_RS02470
uniprot id: A0A0A8JYU8
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS16460
gene id: 1384459:GL4_RS16460
uniprot id: A0A0A8JYH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1384459:GL4 RS00575
gene id: 1384459:GL4_RS00575
uniprot id: A0A0A8JXS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1384459:GL4 RS00705
gene id: 1384459:GL4_RS00705
uniprot id: A0A0A8JZ49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1384459:GL4 RS08210
gene id: 1384459:GL4_RS08210
uniprot id: A0A0A8K2G4
names: Similarity
messages: Belongs to the BolA/IbaG family.

1384459:GL4 RS00700
gene id: 1384459:GL4_RS00700
uniprot id: A0A0A8JYV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

1384459:GL4 RS09930
gene id: 1384459:GL4_RS09930
uniprot id: A0A0A8K660
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS02185
gene id: 1384459:GL4_RS02185
uniprot id: A0A0A8JYP7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1384459:GL4 RS04975
gene id: 1384459:GL4_RS04975
uniprot id: A0A0A8K0J3
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1384459:GL4 RS08835
gene id: 1384459:GL4_RS08835
uniprot id: A0A0A8K425
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

1384459:GL4 RS07845
gene id: 1384459:GL4_RS07845
uniprot id: A0A0A8K4Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1384459:GL4 RS03710
gene id: 1384459:GL4_RS03710
uniprot id: A0A0A8K155
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1384459:GL4 RS04280
gene id: 1384459:GL4_RS04280
uniprot id: A0A0A8K2Y3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1384459:GL4 RS04755
gene id: 1384459:GL4_RS04755
uniprot id: A0A0A8K105
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1384459:GL4 RS06265
gene id: 1384459:GL4_RS06265
uniprot id: A0A0A8K1F2
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1384459:GL4 RS02075
gene id: 1384459:GL4_RS02075
uniprot id: A0A0A8K075
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methanol dehydrogenase subunit 2 family.
messages: Catalyzes the oxidation of primary alcohols including methanol.
messages: Heterotetramer composed of 2 alpha and 2 beta subunits.

1384459:GL4 RS01695
gene id: 1384459:GL4_RS01695
uniprot id: A0A0A8JZH6
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1384459:GL4 RS11470
gene id: 1384459:GL4_RS11470
uniprot id: A0A0A8K4G4
names: Similarity
messages: Belongs to the CutA family.

1384459:GL4 RS06640
gene id: 1384459:GL4_RS06640
uniprot id: A0A0A8K4B3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1384459:GL4 RS01700
gene id: 1384459:GL4_RS01700
uniprot id: A0A0A8JZP4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1384459:GL4 RS10030
gene id: 1384459:GL4_RS10030
uniprot id: A0A0A8K4N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1384459:GL4 RS07785
gene id: 1384459:GL4_RS07785
uniprot id: A0A0A8K4X9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1384459:GL4 RS10425
gene id: 1384459:GL4_RS10425
uniprot id: A0A0A8K4W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1384459:GL4 RS09410
gene id: 1384459:GL4_RS09410
uniprot id: A0A0A8K5Z4
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

1384459:GL4 RS03345
gene id: 1384459:GL4_RS03345
uniprot id: A0A0A8K0W7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1384459:GL4 RS16340
gene id: 1384459:GL4_RS16340
uniprot id: A0A0A8K795
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1384459:GL4 RS07820
gene id: 1384459:GL4_RS07820
uniprot id: A0A0A8K2C8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1384459:GL4 RS10190
gene id: 1384459:GL4_RS10190
uniprot id: A0A0A8K6B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1384459:GL4 RS00165
gene id: 1384459:GL4_RS00165
uniprot id: A0A0A8JYT7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1384459:GL4 RS04790
gene id: 1384459:GL4_RS04790
uniprot id: A0A0A8K392
names: Similarity
messages: Belongs to the threonine synthase family.

1384459:GL4 RS04955
gene id: 1384459:GL4_RS04955
uniprot id: A0A0A8K3B8
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1384459:GL4 RS11215
gene id: 1384459:GL4_RS11215
uniprot id: A0A0A8K5F5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1384459:GL4 RS05240
gene id: 1384459:GL4_RS05240
uniprot id: A0A0A8K1Z6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1384459:GL4 RS10325
gene id: 1384459:GL4_RS10325
uniprot id: A0A0A8K4U4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1384459:GL4 RS06485
gene id: 1384459:GL4_RS06485
uniprot id: A0A0A8K1F8
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1384459:GL4 RS07960
gene id: 1384459:GL4_RS07960
uniprot id: A0A0A8K3I6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1384459:GL4 RS16165
gene id: 1384459:GL4_RS16165
uniprot id: A0A0A8K9J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1384459:GL4 RS09890
gene id: 1384459:GL4_RS09890
uniprot id: A0A0A8K3Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabB family.
messages: Cell membrane
messages: Forms a complex with DabA.
messages: Membrane
messages: Part of an energy-coupled inorganic carbon pump.

1384459:GL4 RS14980
gene id: 1384459:GL4_RS14980
uniprot id: A0A0A8K6I0
names: Similarity
messages: Belongs to the UPF0335 family.

1384459:GL4 RS06440
gene id: 1384459:GL4_RS06440
uniprot id: A0A0A8K1E9
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1384459:GL4 RS01480
gene id: 1384459:GL4_RS01480
uniprot id: A0A0A8JZC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1384459:GL4 RS10580
gene id: 1384459:GL4_RS10580
uniprot id: A0A0A8K3Z0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1384459:GL4 RS01160
gene id: 1384459:GL4_RS01160
uniprot id: A0A0A8JYM0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1384459:GL4 RS03560
gene id: 1384459:GL4_RS03560
uniprot id: A0A0A8K056
names: Similarity
messages: Belongs to the peptidase A24 family.

1384459:GL4 RS07610
gene id: 1384459:GL4_RS07610
uniprot id: A0A0A8K246
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1384459:GL4 RS15135
gene id: 1384459:GL4_RS15135
uniprot id: A0A0A8K941
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1384459:GL4 RS14460
gene id: 1384459:GL4_RS14460
uniprot id: A0A0A8K6N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1384459:GL4 RS12835
gene id: 1384459:GL4_RS12835
uniprot id: A0A0A8K7V6
names: Similarity
messages: Belongs to the glutamine synthetase family.

1384459:GL4 RS12000
gene id: 1384459:GL4_RS12000
uniprot id: A0A0A8K7F5
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS11125
gene id: 1384459:GL4_RS11125
uniprot id: A0A0A8K6W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1384459:GL4 RS09280
gene id: 1384459:GL4_RS09280
uniprot id: A0A0A8K366
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1384459:GL4 RS11985
gene id: 1384459:GL4_RS11985
uniprot id: A0A0A8K581
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1384459:GL4 RS04880
gene id: 1384459:GL4_RS04880
uniprot id: A0A0A8K0H5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1384459:GL4 RS02570
gene id: 1384459:GL4_RS02570
uniprot id: A0A0A8JYW7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1384459:GL4 RS09560
gene id: 1384459:GL4_RS09560
uniprot id: A0A0A8K610
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1384459:GL4 RS04020
gene id: 1384459:GL4_RS04020
uniprot id: A0A0A8K1C6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1384459:GL4 RS12300
gene id: 1384459:GL4_RS12300
uniprot id: A0A0A8K503
names: Similarity
messages: Belongs to the peptidase M1 family.

1384459:GL4 RS14295
gene id: 1384459:GL4_RS14295
uniprot id: A0A0A8K7A6
names: Similarity
messages: Belongs to the pirin family.

1384459:GL4 RS10755
gene id: 1384459:GL4_RS10755
uniprot id: A0A0A8K3Y8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1384459:GL4 RS11100
gene id: 1384459:GL4_RS11100
uniprot id: A0A0A8K6W3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1384459:GL4 RS00425
gene id: 1384459:GL4_RS00425
uniprot id: A0A0A8JYP8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1384459:GL4 RS11060
gene id: 1384459:GL4_RS11060
uniprot id: A0A0A8K4I7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1384459:GL4 RS10280
gene id: 1384459:GL4_RS10280
uniprot id: A0A0A8K3N3
names: Similarity
messages: Belongs to the Gfa family.

1384459:GL4 RS09530
gene id: 1384459:GL4_RS09530
uniprot id: A0A0A8K607
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1384459:GL4 RS11840
gene id: 1384459:GL4_RS11840
uniprot id: A0A0A8K5V1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1384459:GL4 RS03675
gene id: 1384459:GL4_RS03675
uniprot id: A0A0A8K022
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1384459:GL4 RS06375
gene id: 1384459:GL4_RS06375
uniprot id: A0A0A8K1D3
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1384459:GL4 RS04905
gene id: 1384459:GL4_RS04905
uniprot id: A0A0A8K0H9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1384459:GL4 RS01550
gene id: 1384459:GL4_RS01550
uniprot id: A0A0A8JZD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1384459:GL4 RS02540
gene id: 1384459:GL4_RS02540
uniprot id: A0A0A8K0F5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1384459:GL4 RS00090
gene id: 1384459:GL4_RS00090
uniprot id: A0A0A8JXI7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1384459:GL4 RS07995
gene id: 1384459:GL4_RS07995
uniprot id: A0A0A8K522
names: Similarity
messages: Belongs to the fructosamine kinase family.

1384459:GL4 RS08205
gene id: 1384459:GL4_RS08205
uniprot id: A0A0A8K3N4
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1384459:GL4 RS10320
gene id: 1384459:GL4_RS10320
uniprot id: A0A0A8K455
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1384459:GL4 RS09895
gene id: 1384459:GL4_RS09895
uniprot id: A0A0A8K4L7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1384459:GL4 RS07345
gene id: 1384459:GL4_RS07345
uniprot id: A0A0A8K1Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1384459:GL4 RS06270
gene id: 1384459:GL4_RS06270
uniprot id: A0A0A8K1R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1384459:GL4 RS01395
gene id: 1384459:GL4_RS01395
uniprot id: A0A0A8K190
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1384459:GL4 RS08160
gene id: 1384459:GL4_RS08160
uniprot id: A0A0A8K3M4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1384459:GL4 RS11030
gene id: 1384459:GL4_RS11030
uniprot id: A0A0A8K482
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1384459:GL4 RS01495
gene id: 1384459:GL4_RS01495
uniprot id: A0A0A8K1B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1384459:GL4 RS15935
gene id: 1384459:GL4_RS15935
uniprot id: A0A0A8K851
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS11990
gene id: 1384459:GL4_RS11990
uniprot id: A0A0A8K5W5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1384459:GL4 RS09370
gene id: 1384459:GL4_RS09370
uniprot id: A0A0A8K3C9
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS03350
gene id: 1384459:GL4_RS03350
uniprot id: A0A0A8JZB0
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1384459:GL4 RS14480
gene id: 1384459:GL4_RS14480
uniprot id: A0A0A8K6A1
names: Similarity
messages: Belongs to the Gfa family.

1384459:GL4 RS04795
gene id: 1384459:GL4_RS04795
uniprot id: A0A0A8K0N2
names: Similarity
messages: Belongs to the peptidase M16 family.

1384459:GL4 RS00525
gene id: 1384459:GL4_RS00525
uniprot id: A0A0A8JXR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1384459:GL4 RS16070
gene id: 1384459:GL4_RS16070
uniprot id: A0A0A8K9H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ivy family.
messages: Periplasm

1384459:GL4 RS14250
gene id: 1384459:GL4_RS14250
uniprot id: A0A0A8K7A0
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1384459:GL4 RS08420
gene id: 1384459:GL4_RS08420
uniprot id: A0A0A8K311
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

1384459:GL4 RS03835
gene id: 1384459:GL4_RS03835
uniprot id: A0A0A8K182
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1384459:GL4 RS15910
gene id: 1384459:GL4_RS15910
uniprot id: A0A0A8K844
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1384459:GL4 RS01485
gene id: 1384459:GL4_RS01485
uniprot id: A0A0A8JZK4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1384459:GL4 RS06165
gene id: 1384459:GL4_RS06165
uniprot id: A0A0A8K1D2
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS06370
gene id: 1384459:GL4_RS06370
uniprot id: A0A0A8K2N4
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1384459:GL4 RS14810
gene id: 1384459:GL4_RS14810
uniprot id: A0A0A8K6B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nurim family.
messages: Catalyzes the methylation of methanethiol (MeSH) to yield dimethylsulphide (DMS).
messages: Membrane

1384459:GL4 RS01785
gene id: 1384459:GL4_RS01785
uniprot id: A0A0A8K1H8
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1384459:GL4 RS09480
gene id: 1384459:GL4_RS09480
uniprot id: A0A0A8K395
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1384459:GL4 RS09710
gene id: 1384459:GL4_RS09710
uniprot id: A0A0A8K4J3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1384459:GL4 RS06655
gene id: 1384459:GL4_RS06655
uniprot id: A0A0A8K2U7
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

1384459:GL4 RS11150
gene id: 1384459:GL4_RS11150
uniprot id: A0A0A8K6X4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1384459:GL4 RS16135
gene id: 1384459:GL4_RS16135
uniprot id: A0A0A8K734
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1384459:GL4 RS12850
gene id: 1384459:GL4_RS12850
uniprot id: A0A0A8K6B8
names: Similarity
messages: Belongs to the universal stress protein A family.

1384459:GL4 RS08855
gene id: 1384459:GL4_RS08855
uniprot id: A0A0A8K3A2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1384459:GL4 RS06775
gene id: 1384459:GL4_RS06775
uniprot id: A0A0A8K2Y4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1384459:GL4 RS01625
gene id: 1384459:GL4_RS01625
uniprot id: A0A0A8JZM9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1384459:GL4 RS05775
gene id: 1384459:GL4_RS05775
uniprot id: A0A0A8K1G8
names: Similarity
messages: Belongs to the Dps family.

1384459:GL4 RS08365
gene id: 1384459:GL4_RS08365
uniprot id: A0A0A8K5A0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1384459:GL4 RS09090
gene id: 1384459:GL4_RS09090
uniprot id: A0A0A8K336
names: Similarity
messages: Belongs to the OmpW/AlkL family.

1384459:GL4 RS09965
gene id: 1384459:GL4_RS09965
uniprot id: A0A0A8K3Z8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1384459:GL4 RS07895
gene id: 1384459:GL4_RS07895
uniprot id: A0A0A8K501
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1384459:GL4 RS06510
gene id: 1384459:GL4_RS06510
uniprot id: A0A0A8K489
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1384459:GL4 RS00355
gene id: 1384459:GL4_RS00355
uniprot id: A0A0A8JYX3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1384459:GL4 RS01015
gene id: 1384459:GL4_RS01015
uniprot id: A0A0A8JZ27
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS07955
gene id: 1384459:GL4_RS07955
uniprot id: A0A0A8K2T4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1384459:GL4 RS02245
gene id: 1384459:GL4_RS02245
uniprot id: A0A0A8JZE9
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1384459:GL4 RS00490
gene id: 1384459:GL4_RS00490
uniprot id: A0A0A8JYR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1384459:GL4 RS14530
gene id: 1384459:GL4_RS14530
uniprot id: A0A0A8K6A8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

1384459:GL4 RS09885
gene id: 1384459:GL4_RS09885
uniprot id: A0A0A8K3K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

1384459:GL4 RS04730
gene id: 1384459:GL4_RS04730
uniprot id: A0A0A8K101
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).

1384459:GL4 RS07715
gene id: 1384459:GL4_RS07715
uniprot id: A0A0A8K2A7
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1384459:GL4 RS16160
gene id: 1384459:GL4_RS16160
uniprot id: A0A0A8K738
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1384459:GL4 RS04385
gene id: 1384459:GL4_RS04385
uniprot id: A0A0A8K0U8
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS14425
gene id: 1384459:GL4_RS14425
uniprot id: A0A0A8K651
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1384459:GL4 RS00495
gene id: 1384459:GL4_RS00495
uniprot id: A0A0A8JZ02
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

1384459:GL4 RS08495
gene id: 1384459:GL4_RS08495
uniprot id: A0A0A8K3U9
names: Similarity
messages: Belongs to the DEAD box helicase family.

1384459:GL4 RS15715
gene id: 1384459:GL4_RS15715
uniprot id: A0A0A8K6U9
names: Similarity
messages: Belongs to the universal stress protein A family.

1384459:GL4 RS08880
gene id: 1384459:GL4_RS08880
uniprot id: A0A0A8K3A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1384459:GL4 RS08860
gene id: 1384459:GL4_RS08860
uniprot id: A0A0A8K431
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1384459:GL4 RS02535
gene id: 1384459:GL4_RS02535
uniprot id: A0A0A8JZX8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1384459:GL4 RS10595
gene id: 1384459:GL4_RS10595
uniprot id: A0A0A8K3V1
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1384459:GL4 RS03385
gene id: 1384459:GL4_RS03385
uniprot id: A0A0A8JZZ2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1384459:GL4 RS02530
gene id: 1384459:GL4_RS02530
uniprot id: A0A0A8JZJ8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1384459:GL4 RS00520
gene id: 1384459:GL4_RS00520
uniprot id: A0A0A8JZ08
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1384459:GL4 RS11135
gene id: 1384459:GL4_RS11135
uniprot id: A0A0A8K4K6
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1384459:GL4 RS00440
gene id: 1384459:GL4_RS00440
uniprot id: A0A0A8K0M9
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1384459:GL4 RS03720
gene id: 1384459:GL4_RS03720
uniprot id: A0A0A8K2L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1384459:GL4 RS14970
gene id: 1384459:GL4_RS14970
uniprot id: A0A0A8K6E6
names: Similarity
messages: Belongs to the YkuD family.

1384459:GL4 RS05165
gene id: 1384459:GL4_RS05165
uniprot id: A0A0A8K1X9
names: Similarity
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.

1384459:GL4 RS15975
gene id: 1384459:GL4_RS15975
uniprot id: A0A0A8K721
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.
messages: Membrane

1384459:GL4 RS01140
gene id: 1384459:GL4_RS01140
uniprot id: A0A0A8JZ53
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1384459:GL4 RS10345
gene id: 1384459:GL4_RS10345
uniprot id: A0A0A8K456
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

1384459:GL4 RS07635
gene id: 1384459:GL4_RS07635
uniprot id: A0A0A8K249
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1384459:GL4 RS14695
gene id: 1384459:GL4_RS14695
uniprot id: A0A0A8K8Y0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

1384459:GL4 RS12775
gene id: 1384459:GL4_RS12775
uniprot id: A0A0A8K6A2
names: Subcellular Location Annotation
messages: Cytoplasm

1384459:GL4 RS04500
gene id: 1384459:GL4_RS04500
uniprot id: A0A0A8K348
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS02440
gene id: 1384459:GL4_RS02440
uniprot id: A0A0A8JZW9
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1384459:GL4 RS16965
gene id: 1384459:GL4_RS16965
uniprot id: A0A0A8K7E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1384459:GL4 RS01810
gene id: 1384459:GL4_RS01810
uniprot id: A0A0A8K1I3
names: Similarity
messages: Belongs to the YciI family.

1384459:GL4 RS08635
gene id: 1384459:GL4_RS08635
uniprot id: A0A0A8K2U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
messages: Cytoplasm

1384459:GL4 RS14625
gene id: 1384459:GL4_RS14625
uniprot id: A0A0A8K6C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1384459:GL4 RS11370
gene id: 1384459:GL4_RS11370
uniprot id: A0A0A8K4E2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1384459:GL4 RS07945
gene id: 1384459:GL4_RS07945
uniprot id: A0A0A8K511
names: Similarity
messages: Belongs to the FBPase class 2 family.

1384459:GL4 RS10470
gene id: 1384459:GL4_RS10470
uniprot id: A0A0A8K4X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1384459:GL4 RS10700
gene id: 1384459:GL4_RS10700
uniprot id: A0A0A8K4C1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1384459:GL4 RS01610
gene id: 1384459:GL4_RS01610
uniprot id: A0A0A8K1E0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1384459:GL4 RS08515
gene id: 1384459:GL4_RS08515
uniprot id: A0A0A8K329
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1384459:GL4 RS06280
gene id: 1384459:GL4_RS06280
uniprot id: A0A0A8K1B2
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS07550
gene id: 1384459:GL4_RS07550
uniprot id: A0A0A8K2L8
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1384459:GL4 RS01175
gene id: 1384459:GL4_RS01175
uniprot id: A0A0A8JY34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

1384459:GL4 RS11860
gene id: 1384459:GL4_RS11860
uniprot id: A0A0A8K565
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1384459:GL4 RS12645
gene id: 1384459:GL4_RS12645
uniprot id: A0A0A8K520
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1384459:GL4 RS10490
gene id: 1384459:GL4_RS10490
uniprot id: A0A0A8K485
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1384459:GL4 RS00180
gene id: 1384459:GL4_RS00180
uniprot id: A0A0A8JYK3
names: Function
names: Similarity
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.

1384459:GL4 RS14440
gene id: 1384459:GL4_RS14440
uniprot id: A0A0A8K7C0
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS00530
gene id: 1384459:GL4_RS00530
uniprot id: A0A0A8K0Q0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

1384459:GL4 RS10960
gene id: 1384459:GL4_RS10960
uniprot id: A0A0A8K4G7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1384459:GL4 RS05265
gene id: 1384459:GL4_RS05265
uniprot id: A0A0A8K202
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1384459:GL4 RS10300
gene id: 1384459:GL4_RS10300
uniprot id: A0A0A8K4T9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde.

1384459:GL4 RS07745
gene id: 1384459:GL4_RS07745
uniprot id: A0A0A8K2P9
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1384459:GL4 RS02860
gene id: 1384459:GL4_RS02860
uniprot id: A0A0A8K230
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS14740
gene id: 1384459:GL4_RS14740
uniprot id: A0A0A8K8Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1384459:GL4 RS05080
gene id: 1384459:GL4_RS05080
uniprot id: A0A0A8K0S6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1384459:GL4 RS10380
gene id: 1384459:GL4_RS10380
uniprot id: A0A0A8K3Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1384459:GL4 RS02800
gene id: 1384459:GL4_RS02800
uniprot id: A0A0A8K0K7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1384459:GL4 RS10740
gene id: 1384459:GL4_RS10740
uniprot id: A0A0A8K424
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

1384459:GL4 RS03410
gene id: 1384459:GL4_RS03410
uniprot id: A0A0A8JZZ4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1384459:GL4 RS08105
gene id: 1384459:GL4_RS08105
uniprot id: A0A0A8K2I5
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS02490
gene id: 1384459:GL4_RS02490
uniprot id: A0A0A8K0E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1384459:GL4 RS13195
gene id: 1384459:GL4_RS13195
uniprot id: A0A0A8K6J0
names: Subcellular Location Annotation
messages: Cytoplasm

1384459:GL4 RS05975
gene id: 1384459:GL4_RS05975
uniprot id: A0A0A8K192
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nurim family.
messages: Catalyzes the methylation of methanethiol (MeSH) to yield dimethylsulphide (DMS).
messages: Membrane

1384459:GL4 RS10230
gene id: 1384459:GL4_RS10230
uniprot id: A0A0A8K4S3
names: Similarity
messages: Belongs to the TrpC family.

1384459:GL4 RS10225
gene id: 1384459:GL4_RS10225
uniprot id: A0A0A8K436
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1384459:GL4 RS09565
gene id: 1384459:GL4_RS09565
uniprot id: A0A0A8K3G2
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1384459:GL4 RS07660
gene id: 1384459:GL4_RS07660
uniprot id: A0A0A8K4V2
names: Similarity
messages: Belongs to the peptidase M24B family.

1384459:GL4 RS00475
gene id: 1384459:GL4_RS00475
uniprot id: A0A0A8JYZ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1384459:GL4 RS00010
gene id: 1384459:GL4_RS00010
uniprot id: A0A0A8JYQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1384459:GL4 RS13165
gene id: 1384459:GL4_RS13165
uniprot id: A0A0A8K5G5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

1384459:GL4 RS13055
gene id: 1384459:GL4_RS13055
uniprot id: A0A0A8K5E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1384459:GL4 RS04700
gene id: 1384459:GL4_RS04700
uniprot id: A0A0A8K0L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1384459:GL4 RS09115
gene id: 1384459:GL4_RS09115
uniprot id: A0A0A8K343
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1384459:GL4 RS11200
gene id: 1384459:GL4_RS11200
uniprot id: A0A0A8K6Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1384459:GL4 RS13290
gene id: 1384459:GL4_RS13290
uniprot id: A0A0A8K5J0
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1384459:GL4 RS15845
gene id: 1384459:GL4_RS15845
uniprot id: A0A0A8K9D5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1384459:GL4 RS08240
gene id: 1384459:GL4_RS08240
uniprot id: A0A0A8K572
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

1384459:GL4 RS15185
gene id: 1384459:GL4_RS15185
uniprot id: A0A0A8K6L1
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1384459:GL4 RS14265
gene id: 1384459:GL4_RS14265
uniprot id: A0A0A8K6K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1384459:GL4 RS07815
gene id: 1384459:GL4_RS07815
uniprot id: A0A0A8K4Y5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1384459:GL4 RS02455
gene id: 1384459:GL4_RS02455
uniprot id: A0A0A8K1U8
names: Similarity
messages: Belongs to the peptidase C59 family.

1384459:GL4 RS14960
gene id: 1384459:GL4_RS14960
uniprot id: A0A0A8K6W2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1384459:GL4 RS00330
gene id: 1384459:GL4_RS00330
uniprot id: A0A0A8JYW8
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS09535
gene id: 1384459:GL4_RS09535
uniprot id: A0A0A8K3F8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1384459:GL4 RS03805
gene id: 1384459:GL4_RS03805
uniprot id: A0A0A8K176
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1384459:GL4 RS01930
gene id: 1384459:GL4_RS01930
uniprot id: A0A0A8JYL3
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1384459:GL4 RS10080
gene id: 1384459:GL4_RS10080
uniprot id: A0A0A8K4P4
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

1384459:GL4 RS09600
gene id: 1384459:GL4_RS09600
uniprot id: A0A0A8K4H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1384459:GL4 RS16385
gene id: 1384459:GL4_RS16385
uniprot id: A0A0A8K7A4
names: Similarity
messages: Belongs to the AHA1 family.

1384459:GL4 RS02690
gene id: 1384459:GL4_RS02690
uniprot id: A0A0A8K1Z4
names: Similarity
messages: Belongs to the peptidase S49 family.

1384459:GL4 RS01080
gene id: 1384459:GL4_RS01080
uniprot id: A0A0A8K117
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1384459:GL4 RS11070
gene id: 1384459:GL4_RS11070
uniprot id: A0A0A8K458
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1384459:GL4 RS10890
gene id: 1384459:GL4_RS10890
uniprot id: A0A0A8K4F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1384459:GL4 RS09670
gene id: 1384459:GL4_RS09670
uniprot id: A0A0A8K621
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1384459:GL4 RS15990
gene id: 1384459:GL4_RS15990
uniprot id: A0A0A8K701
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

1384459:GL4 RS09985
gene id: 1384459:GL4_RS09985
uniprot id: A0A0A8K669
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1384459:GL4 RS04685
gene id: 1384459:GL4_RS04685
uniprot id: A0A0A8K1P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

1384459:GL4 RS10070
gene id: 1384459:GL4_RS10070
uniprot id: A0A0A8K3N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1384459:GL4 RS01705
gene id: 1384459:GL4_RS01705
uniprot id: A0A0A8JYD9
names: Similarity
messages: Belongs to the UPF0434 family.

1384459:GL4 RS15980
gene id: 1384459:GL4_RS15980
uniprot id: A0A0A8K7C5
names: Similarity
messages: Belongs to the BolA/IbaG family.

1384459:GL4 RS11240
gene id: 1384459:GL4_RS11240
uniprot id: A0A0A8K5G1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1384459:GL4 RS11075
gene id: 1384459:GL4_RS11075
uniprot id: A0A0A8K6V7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1384459:GL4 RS06645
gene id: 1384459:GL4_RS06645
uniprot id: A0A0A8K1M9
names: PTM
messages: Binds 1 heme group per subunit.

1384459:GL4 RS08200
gene id: 1384459:GL4_RS08200
uniprot id: A0A0A8K2X5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1384459:GL4 RS03320
gene id: 1384459:GL4_RS03320
uniprot id: A0A0A8K0W1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1384459:GL4 RS04810
gene id: 1384459:GL4_RS04810
uniprot id: A0A0A8K0G0
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1384459:GL4 RS06275
gene id: 1384459:GL4_RS06275
uniprot id: A0A0A8K2L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

1384459:GL4 RS13040
gene id: 1384459:GL4_RS13040
uniprot id: A0A0A8K6G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1384459:GL4 RS04760
gene id: 1384459:GL4_RS04760
uniprot id: A0A0A8K1Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1384459:GL4 RS06135
gene id: 1384459:GL4_RS06135
uniprot id: A0A0A8K401
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

1384459:GL4 RS03795
gene id: 1384459:GL4_RS03795
uniprot id: A0A0A8K2M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1384459:GL4 RS13085
gene id: 1384459:GL4_RS13085
uniprot id: A0A0A8K806
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1384459:GL4 RS02710
gene id: 1384459:GL4_RS02710
uniprot id: A0A0A8JYZ6
names: Similarity
messages: Belongs to the TrpF family.

1384459:GL4 RS06465
gene id: 1384459:GL4_RS06465
uniprot id: A0A0A8K479
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1384459:GL4 RS13680
gene id: 1384459:GL4_RS13680
uniprot id: A0A0A8K6V8
names: Similarity
messages: Belongs to the UPF0234 family.

1384459:GL4 RS05190
gene id: 1384459:GL4_RS05190
uniprot id: A0A0A8K1Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1384459:GL4 RS10830
gene id: 1384459:GL4_RS10830
uniprot id: A0A0A8K6Q0
names: Similarity
messages: Belongs to the peptidase S11 family.

1384459:GL4 RS07480
gene id: 1384459:GL4_RS07480
uniprot id: A0A0A8K390
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1384459:GL4 RS04765
gene id: 1384459:GL4_RS04765
uniprot id: A0A0A8K0F3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1384459:GL4 RS01765
gene id: 1384459:GL4_RS01765
uniprot id: A0A0A8JZ35
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1384459:GL4 RS01045
gene id: 1384459:GL4_RS01045
uniprot id: A0A0A8JZB1
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1384459:GL4 RS06445
gene id: 1384459:GL4_RS06445
uniprot id: A0A0A8K474
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1384459:GL4 RS13345
gene id: 1384459:GL4_RS13345
uniprot id: A0A0A8K5U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

1384459:GL4 RS01945
gene id: 1384459:GL4_RS01945
uniprot id: A0A0A8JZQ2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1384459:GL4 RS08525
gene id: 1384459:GL4_RS08525
uniprot id: A0A0A8K2N5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1384459:GL4 RS04300
gene id: 1384459:GL4_RS04300
uniprot id: A0A0A8JZV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1384459:GL4 RS14070
gene id: 1384459:GL4_RS14070
uniprot id: A0A0A8K5Z8
names: Similarity
messages: Belongs to the MT-A70-like family.

1384459:GL4 RS14735
gene id: 1384459:GL4_RS14735
uniprot id: A0A0A8K6A3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1384459:GL4 RS00290
gene id: 1384459:GL4_RS00290
uniprot id: A0A0A8K0K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1384459:GL4 RS02520
gene id: 1384459:GL4_RS02520
uniprot id: A0A0A8JYV8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1384459:GL4 RS16570
gene id: 1384459:GL4_RS16570
uniprot id: A0A0A8K0I8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1384459:GL4 RS07840
gene id: 1384459:GL4_RS07840
uniprot id: A0A0A8K284
names: Similarity
messages: Belongs to the class-D beta-lactamase family.

1384459:GL4 RS04665
gene id: 1384459:GL4_RS04665
uniprot id: A0A0A8K0E0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1384459:GL4 RS02840
gene id: 1384459:GL4_RS02840
uniprot id: A0A0A8JZQ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1384459:GL4 RS11175
gene id: 1384459:GL4_RS11175
uniprot id: A0A0A8K6X9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1384459:GL4 RS02510
gene id: 1384459:GL4_RS02510
uniprot id: A0A0A8JZX6
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1384459:GL4 RS14895
gene id: 1384459:GL4_RS14895
uniprot id: A0A0A8K7I2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1384459:GL4 RS15035
gene id: 1384459:GL4_RS15035
uniprot id: A0A0A8K6I8
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS07915
gene id: 1384459:GL4_RS07915
uniprot id: A0A0A8K298
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1384459:GL4 RS10850
gene id: 1384459:GL4_RS10850
uniprot id: A0A0A8K411
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1384459:GL4 RS03735
gene id: 1384459:GL4_RS03735
uniprot id: A0A0A8K160
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1384459:GL4 RS12270
gene id: 1384459:GL4_RS12270
uniprot id: A0A0A8K7J0
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

1384459:GL4 RS08305
gene id: 1384459:GL4_RS08305
uniprot id: A0A0A8K3Q6
names: Similarity
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1384459:GL4 RS15045
gene id: 1384459:GL4_RS15045
uniprot id: A0A0A8K7K7
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS15395
gene id: 1384459:GL4_RS15395
uniprot id: A0A0A8K6M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1384459:GL4 RS11945
gene id: 1384459:GL4_RS11945
uniprot id: A0A0A8K5W0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1384459:GL4 RS00105
gene id: 1384459:GL4_RS00105
uniprot id: A0A0A8JY40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1384459:GL4 RS12335
gene id: 1384459:GL4_RS12335
uniprot id: A0A0A8K614
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1384459:GL4 RS02410
gene id: 1384459:GL4_RS02410
uniprot id: A0A0A8JZH8
names: Similarity
messages: Belongs to the nitroreductase family. HadB/RutE subfamily.

1384459:GL4 RS15965
gene id: 1384459:GL4_RS15965
uniprot id: A0A0A8K6Z6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1384459:GL4 RS04540
gene id: 1384459:GL4_RS04540
uniprot id: A0A0A8K1M7
names: Function
names: Similarity
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.

1384459:GL4 RS08220
gene id: 1384459:GL4_RS08220
uniprot id: A0A0A8K2L2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1384459:GL4 RS10050
gene id: 1384459:GL4_RS10050
uniprot id: A0A0A8K410
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1384459:GL4 RS06795
gene id: 1384459:GL4_RS06795
uniprot id: A0A0A8K288
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1384459:GL4 RS02775
gene id: 1384459:GL4_RS02775
uniprot id: A0A0A8K0K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1384459:GL4 RS03400
gene id: 1384459:GL4_RS03400
uniprot id: A0A0A8JZB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1384459:GL4 RS05160
gene id: 1384459:GL4_RS05160
uniprot id: A0A0A8K169
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1384459:GL4 RS13325
gene id: 1384459:GL4_RS13325
uniprot id: A0A0A8K6L9
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

1384459:GL4 RS05335
gene id: 1384459:GL4_RS05335
uniprot id: A0A0A8K0W8
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS01050
gene id: 1384459:GL4_RS01050
uniprot id: A0A0A8JY08
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1384459:GL4 RS07940
gene id: 1384459:GL4_RS07940
uniprot id: A0A0A8K2A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1384459:GL4 RS15825
gene id: 1384459:GL4_RS15825
uniprot id: A0A0A8K6Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

1384459:GL4 RS14670
gene id: 1384459:GL4_RS14670
uniprot id: A0A0A8K8X7
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1384459:GL4 RS10530
gene id: 1384459:GL4_RS10530
uniprot id: A0A0A8K6I3
names: Similarity
messages: Belongs to the CFA/CMAS family.

1384459:GL4 RS12250
gene id: 1384459:GL4_RS12250
uniprot id: A0A0A8K4Z5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1384459:GL4 RS04610
gene id: 1384459:GL4_RS04610
uniprot id: A0A0A8K1N6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1384459:GL4 RS11085
gene id: 1384459:GL4_RS11085
uniprot id: A0A0A8K4J4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1384459:GL4 RS03620
gene id: 1384459:GL4_RS03620
uniprot id: A0A0A8K2I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

1384459:GL4 RS15670
gene id: 1384459:GL4_RS15670
uniprot id: A0A0A8K6T8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1384459:GL4 RS07580
gene id: 1384459:GL4_RS07580
uniprot id: A0A0A8K3A7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1384459:GL4 RS12995
gene id: 1384459:GL4_RS12995
uniprot id: A0A0A8K590
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1384459:GL4 RS06130
gene id: 1384459:GL4_RS06130
uniprot id: A0A0A8K180
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1384459:GL4 RS02635
gene id: 1384459:GL4_RS02635
uniprot id: A0A0A8K0H1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1384459:GL4 RS05040
gene id: 1384459:GL4_RS05040
uniprot id: A0A0A8K1V4
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the reversible phosphorylation of pyruvate and phosphate.

1384459:GL4 RS02170
gene id: 1384459:GL4_RS02170
uniprot id: A0A0A8JZD7
names: Similarity
messages: Belongs to the UPF0235 family.

1384459:GL4 RS00465
gene id: 1384459:GL4_RS00465
uniprot id: A0A0A8JY96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1384459:GL4 RS08450
gene id: 1384459:GL4_RS08450
uniprot id: A0A0A8K2L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1384459:GL4 RS04785
gene id: 1384459:GL4_RS04785
uniprot id: A0A0A8K0F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1384459:GL4 RS04525
gene id: 1384459:GL4_RS04525
uniprot id: A0A0A8K351
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1384459:GL4 RS15630
gene id: 1384459:GL4_RS15630
uniprot id: A0A0A8K9B2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1384459:GL4 RS02175
gene id: 1384459:GL4_RS02175
uniprot id: A0A0A8JZT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1384459:GL4 RS01835
gene id: 1384459:GL4_RS01835
uniprot id: A0A0A8K1I8
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1384459:GL4 RS13365
gene id: 1384459:GL4_RS13365
uniprot id: A0A0A8K5K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Could be part of an ABC transporter complex.
messages: Membrane

1384459:GL4 RS01875
gene id: 1384459:GL4_RS01875
uniprot id: A0A0A8JZL1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1384459:GL4 RS10900
gene id: 1384459:GL4_RS10900
uniprot id: A0A0A8K421
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS04065
gene id: 1384459:GL4_RS04065
uniprot id: A0A0A8K0I2
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

1384459:GL4 RS15305
gene id: 1384459:GL4_RS15305
uniprot id: A0A0A8K961
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.

1384459:GL4 RS05865
gene id: 1384459:GL4_RS05865
uniprot id: A0A0A8K3U2
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS02675
gene id: 1384459:GL4_RS02675
uniprot id: A0A0A8JZM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1384459:GL4 RS04565
gene id: 1384459:GL4_RS04565
uniprot id: A0A0A8K1N0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1384459:GL4 RS11140
gene id: 1384459:GL4_RS11140
uniprot id: A0A0A8K5D6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1384459:GL4 RS00020
gene id: 1384459:GL4_RS00020
uniprot id: A0A0A8K0F1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1384459:GL4 RS16140
gene id: 1384459:GL4_RS16140
uniprot id: A0A0A8K9I5
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1384459:GL4 RS13185
gene id: 1384459:GL4_RS13185
uniprot id: A0A0A8K830
names: Cofactor
names: Function
names: Miscellaneous
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1384459:GL4 RS03745
gene id: 1384459:GL4_RS03745
uniprot id: A0A0A8K2L5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1384459:GL4 RS16845
gene id: 1384459:GL4_RS16845
uniprot id: A0A0A8K5C2
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS03785
gene id: 1384459:GL4_RS03785
uniprot id: A0A0A8K171
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1384459:GL4 RS08250
gene id: 1384459:GL4_RS08250
uniprot id: A0A0A8K2Y0
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1384459:GL4 RS11145
gene id: 1384459:GL4_RS11145
uniprot id: A0A0A8K473
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1384459:GL4 RS08470
gene id: 1384459:GL4_RS08470
uniprot id: A0A0A8K3U4
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1384459:GL4 RS06750
gene id: 1384459:GL4_RS06750
uniprot id: A0A0A8K2W8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

1384459:GL4 RS00515
gene id: 1384459:GL4_RS00515
uniprot id: A0A0A8JYR9
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1384459:GL4 RS11995
gene id: 1384459:GL4_RS11995
uniprot id: A0A0A8K4R0
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

1384459:GL4 RS10020
gene id: 1384459:GL4_RS10020
uniprot id: A0A0A8K3M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1384459:GL4 RS02165
gene id: 1384459:GL4_RS02165
uniprot id: A0A0A8K1Q3
names: Similarity
messages: Belongs to the YggT family.

1384459:GL4 RS01775
gene id: 1384459:GL4_RS01775
uniprot id: A0A0A8JZQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1384459:GL4 RS13880
gene id: 1384459:GL4_RS13880
uniprot id: A0A0A8K682
names: Similarity
messages: Belongs to the peptidase C40 family.

1384459:GL4 RS09990
gene id: 1384459:GL4_RS09990
uniprot id: A0A0A8K3M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1384459:GL4 RS09080
gene id: 1384459:GL4_RS09080
uniprot id: A0A0A8K2Z4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1384459:GL4 RS13605
gene id: 1384459:GL4_RS13605
uniprot id: A0A0A8K6U6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1384459:GL4 RS08460
gene id: 1384459:GL4_RS08460
uniprot id: A0A0A8K2R3
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

1384459:GL4 RS05700
gene id: 1384459:GL4_RS05700
uniprot id: A0A0A8K0Y0
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1384459:GL4 RS03680
gene id: 1384459:GL4_RS03680
uniprot id: A0A0A8K080
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1384459:GL4 RS10270
gene id: 1384459:GL4_RS10270
uniprot id: A0A0A8K445
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1384459:GL4 RS00625
gene id: 1384459:GL4_RS00625
uniprot id: A0A0A8JXS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1384459:GL4 RS00580
gene id: 1384459:GL4_RS00580
uniprot id: A0A0A8K0R0
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1384459:GL4 RS10185
gene id: 1384459:GL4_RS10185
uniprot id: A0A0A8K3L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1384459:GL4 RS12190
gene id: 1384459:GL4_RS12190
uniprot id: A0A0A8K4U1
names: Similarity
messages: Belongs to the GST superfamily.

1384459:GL4 RS04710
gene id: 1384459:GL4_RS04710
uniprot id: A0A0A8K1P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Membrane

1384459:GL4 RS01720
gene id: 1384459:GL4_RS01720
uniprot id: A0A0A8JZI3
names: Similarity
messages: Belongs to the PRORSD1 family.

1384459:GL4 RS15950
gene id: 1384459:GL4_RS15950
uniprot id: A0A0A8K716
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1384459:GL4 RS15075
gene id: 1384459:GL4_RS15075
uniprot id: A0A0A8K6G5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

1384459:GL4 RS06085
gene id: 1384459:GL4_RS06085
uniprot id: A0A0A8K170
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1384459:GL4 RS04035
gene id: 1384459:GL4_RS04035
uniprot id: A0A0A8K053
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1384459:GL4 RS08565
gene id: 1384459:GL4_RS08565
uniprot id: A0A0A8K339
names: Function
messages: Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).

1384459:GL4 RS03390
gene id: 1384459:GL4_RS03390
uniprot id: A0A0A8K043
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1384459:GL4 RS00045
gene id: 1384459:GL4_RS00045
uniprot id: A0A0A8K0F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1384459:GL4 RS14575
gene id: 1384459:GL4_RS14575
uniprot id: A0A0A8K6B7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1384459:GL4 RS09765
gene id: 1384459:GL4_RS09765
uniprot id: A0A0A8K3E2
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1384459:GL4 RS02060
gene id: 1384459:GL4_RS02060
uniprot id: T2HQE2
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1384459:GL4 RS00140
gene id: 1384459:GL4_RS00140
uniprot id: A0A0A8JYT2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1384459:GL4 RS00385
gene id: 1384459:GL4_RS00385
uniprot id: A0A0A8JXN8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1384459:GL4 RS13110
gene id: 1384459:GL4_RS13110
uniprot id: A0A0A8K811
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1384459:GL4 RS05215
gene id: 1384459:GL4_RS05215
uniprot id: A0A0A8K1Z0
names: Similarity
messages: Belongs to the TlyA family.

1384459:GL4 RS15600
gene id: 1384459:GL4_RS15600
uniprot id: A0A0A8K6S2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1384459:GL4 RS12605
gene id: 1384459:GL4_RS12605
uniprot id: A0A0A8K513
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1384459:GL4 RS03655
gene id: 1384459:GL4_RS03655
uniprot id: A0A0A8K073
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1384459:GL4 RS12965
gene id: 1384459:GL4_RS12965
uniprot id: A0A0A8K584
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1384459:GL4 RS10220
gene id: 1384459:GL4_RS10220
uniprot id: A0A0A8K3R3
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1384459:GL4 RS10515
gene id: 1384459:GL4_RS10515
uniprot id: A0A0A8K490
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1384459:GL4 RS10065
gene id: 1384459:GL4_RS10065
uniprot id: A0A0A8K684
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1384459:GL4 RS03910
gene id: 1384459:GL4_RS03910
uniprot id: A0A0A8K2Q4
names: Similarity
messages: Belongs to the GcvT family.

1384459:GL4 RS00600
gene id: 1384459:GL4_RS00600
uniprot id: A0A0A8JXS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1384459:GL4 RS12905
gene id: 1384459:GL4_RS12905
uniprot id: A0A0A8K5B6
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS08290
gene id: 1384459:GL4_RS08290
uniprot id: A0A0A8K583
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS07500
gene id: 1384459:GL4_RS07500
uniprot id: A0A0A8K2K9
names: Similarity
messages: Belongs to the oxoprolinase family.

1384459:GL4 RS13445
gene id: 1384459:GL4_RS13445
uniprot id: A0A0A8K6Q3
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1384459:GL4 RS10695
gene id: 1384459:GL4_RS10695
uniprot id: A0A0A8K414
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.
messages: Hydrolyzes indole-3-acetamide (IAM) into indole-3-acetic acid (IAA).

1384459:GL4 RS11185
gene id: 1384459:GL4_RS11185
uniprot id: A0A0A8K4L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1384459:GL4 RS06885
gene id: 1384459:GL4_RS06885
uniprot id: A0A0A8K1X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1384459:GL4 RS10910
gene id: 1384459:GL4_RS10910
uniprot id: A0A0A8K457
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

1384459:GL4 RS08165
gene id: 1384459:GL4_RS08165
uniprot id: A0A0A8K2F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1384459:GL4 RS03480
gene id: 1384459:GL4_RS03480
uniprot id: A0A0A8K006
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1384459:GL4 RS11875
gene id: 1384459:GL4_RS11875
uniprot id: A0A0A8K7D9
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS06330
gene id: 1384459:GL4_RS06330
uniprot id: A0A0A8K446
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex. FixP subunit is required for transferring electrons from donor cytochrome c via its heme groups to FixO subunit. From there, electrons are shuttled to the catalytic binuclear center of FixN subunit where oxygen reduction takes place. The complex also functions as a proton pump.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase at least composed of FixN, FixO, FixQ and FixP.
messages: Membrane

1384459:GL4 RS04965
gene id: 1384459:GL4_RS04965
uniprot id: A0A0A8K138
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1384459:GL4 RS08605
gene id: 1384459:GL4_RS08605
uniprot id: A0A0A8K5F9
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS10705
gene id: 1384459:GL4_RS10705
uniprot id: A0A0A8K531
names: Similarity
messages: Belongs to the UPF0173 family.

1384459:GL4 RS09235
gene id: 1384459:GL4_RS09235
uniprot id: A0A0A8K342
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1384459:GL4 RS13385
gene id: 1384459:GL4_RS13385
uniprot id: A0A0A8K875
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

1384459:GL4 RS06770
gene id: 1384459:GL4_RS06770
uniprot id: A0A0A8K266
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1384459:GL4 RS06470
gene id: 1384459:GL4_RS06470
uniprot id: A0A0A8K1J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1384459:GL4 RS02755
gene id: 1384459:GL4_RS02755
uniprot id: A0A0A8K0J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1384459:GL4 RS11105
gene id: 1384459:GL4_RS11105
uniprot id: A0A0A8K497
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1384459:GL4 RS09515
gene id: 1384459:GL4_RS09515
uniprot id: A0A0A8K3T1
names: Similarity
messages: Belongs to the YkuD family.

1384459:GL4 RS10055
gene id: 1384459:GL4_RS10055
uniprot id: A0A0A8K4P0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1384459:GL4 RS00260
gene id: 1384459:GL4_RS00260
uniprot id: A0A0A8JXL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1384459:GL4 RS05515
gene id: 1384459:GL4_RS05515
uniprot id: A0A0A8K1C1
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

1384459:GL4 RS09095
gene id: 1384459:GL4_RS09095
uniprot id: A0A0A8K3G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1384459:GL4 RS05900
gene id: 1384459:GL4_RS05900
uniprot id: A0A0A8K1I9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1384459:GL4 RS10105
gene id: 1384459:GL4_RS10105
uniprot id: A0A0A8K4P7
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1384459:GL4 RS05855
gene id: 1384459:GL4_RS05855
uniprot id: A0A0A8K2B4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1384459:GL4 RS00160
gene id: 1384459:GL4_RS00160
uniprot id: A0A0A8JYJ9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1384459:GL4 RS02545
gene id: 1384459:GL4_RS02545
uniprot id: A0A0A8JYW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

1384459:GL4 RS09445
gene id: 1384459:GL4_RS09445
uniprot id: A0A0A8K3S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1384459:GL4 RS14665
gene id: 1384459:GL4_RS14665
uniprot id: A0A0A8K688
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1384459:GL4 RS09960
gene id: 1384459:GL4_RS09960
uniprot id: A0A0A8K3L9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1384459:GL4 RS09455
gene id: 1384459:GL4_RS09455
uniprot id: A0A0A8K391
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1384459:GL4 RS11575
gene id: 1384459:GL4_RS11575
uniprot id: A0A0A8K765
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1384459:GL4 RS10630
gene id: 1384459:GL4_RS10630
uniprot id: A0A0A8K3W2
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1384459:GL4 RS13425
gene id: 1384459:GL4_RS13425
uniprot id: A0A0A8K5H9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

1384459:GL4 RS09465
gene id: 1384459:GL4_RS09465
uniprot id: A0A0A8K3E6
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1384459:GL4 RS06365
gene id: 1384459:GL4_RS06365
uniprot id: A0A0A8K1U0
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS10710
gene id: 1384459:GL4_RS10710
uniprot id: A0A0A8K3X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1384459:GL4 RS08550
gene id: 1384459:GL4_RS08550
uniprot id: A0A0A8K2N9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.
messages: In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP. P-II-UMP allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme. Conversely, in nitrogen excess P-II is deuridylated and promotes the adenylation of GS. P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is uridylylated to P-II-UMP, these events are reversed.

1384459:GL4 RS01890
gene id: 1384459:GL4_RS01890
uniprot id: A0A0A8K1J8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1384459:GL4 RS08090
gene id: 1384459:GL4_RS08090
uniprot id: A0A0A8K3L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane
messages: Membrane

1384459:GL4 RS00255
gene id: 1384459:GL4_RS00255
uniprot id: A0A0A8JYV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1384459:GL4 RS00250
gene id: 1384459:GL4_RS00250
uniprot id: A0A0A8JYL5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1384459:GL4 RS04830
gene id: 1384459:GL4_RS04830
uniprot id: A0A0A8K0G5
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

1384459:GL4 RS10085
gene id: 1384459:GL4_RS10085
uniprot id: A0A0A8K3J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1384459:GL4 RS05420
gene id: 1384459:GL4_RS05420
uniprot id: A0A0A8K0Y4
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS08395
gene id: 1384459:GL4_RS08395
uniprot id: A0A0A8K2P7
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1384459:GL4 RS06630
gene id: 1384459:GL4_RS06630
uniprot id: A0A0A8K2U3
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1384459:GL4 RS01575
gene id: 1384459:GL4_RS01575
uniprot id: A0A0A8JZE1
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1384459:GL4 RS12175
gene id: 1384459:GL4_RS12175
uniprot id: A0A0A8K4Y4
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1384459:GL4 RS12005
gene id: 1384459:GL4_RS12005
uniprot id: A0A0A8K4V7
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1384459:GL4 RS01055
gene id: 1384459:GL4_RS01055
uniprot id: A0A0A8K111
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS13155
gene id: 1384459:GL4_RS13155
uniprot id: A0A0A8K5C1
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1384459:GL4 RS01445
gene id: 1384459:GL4_RS01445
uniprot id: A0A0A8K1A1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1384459:GL4 RS05460
gene id: 1384459:GL4_RS05460
uniprot id: A0A0A8K0T2
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1384459:GL4 RS11910
gene id: 1384459:GL4_RS11910
uniprot id: A0A0A8K4U3
names: Similarity
messages: Belongs to the universal stress protein A family.

1384459:GL4 RS02205
gene id: 1384459:GL4_RS02205
uniprot id: A0A0A8K095
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1384459:GL4 RS09995
gene id: 1384459:GL4_RS09995
uniprot id: A0A0A8K4N3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1384459:GL4 RS10060
gene id: 1384459:GL4_RS10060
uniprot id: A0A0A8K3J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1384459:GL4 RS01795
gene id: 1384459:GL4_RS01795
uniprot id: A0A0A8JZK0
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

1384459:GL4 RS05495
gene id: 1384459:GL4_RS05495
uniprot id: A0A0A8K243
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1384459:GL4 RS08000
gene id: 1384459:GL4_RS08000
uniprot id: A0A0A8K2G3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1384459:GL4 RS02585
gene id: 1384459:GL4_RS02585
uniprot id: A0A0A8JZY2
names: Similarity
messages: Belongs to the Gfa family.

1384459:GL4 RS02680
gene id: 1384459:GL4_RS02680
uniprot id: A0A0A8JZZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1384459:GL4 RS16045
gene id: 1384459:GL4_RS16045
uniprot id: A0A0A8K737
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1384459:GL4 RS10545
gene id: 1384459:GL4_RS10545
uniprot id: A0A0A8K4Z4
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1384459:GL4 RS11505
gene id: 1384459:GL4_RS11505
uniprot id: A0A0A8K4G9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1384459:GL4 RS11205
gene id: 1384459:GL4_RS11205
uniprot id: A0A0A8K4B5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1384459:GL4 RS15060
gene id: 1384459:GL4_RS15060
uniprot id: A0A0A8K6J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1384459:GL4 RS04825
gene id: 1384459:GL4_RS04825
uniprot id: A0A0A8K1R9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1384459:GL4 RS15200
gene id: 1384459:GL4_RS15200
uniprot id: A0A0A8K6I5
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1384459:GL4 RS09430
gene id: 1384459:GL4_RS09430
uniprot id: A0A0A8K387
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1384459:GL4 RS03800
gene id: 1384459:GL4_RS03800
uniprot id: A0A0A8K0A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1384459:GL4 RS11155
gene id: 1384459:GL4_RS11155
uniprot id: A0A0A8K4A6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1384459:GL4 RS11605
gene id: 1384459:GL4_RS11605
uniprot id: A0A0A8K4J8
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS04835
gene id: 1384459:GL4_RS04835
uniprot id: A0A0A8K398
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1384459:GL4 RS04240
gene id: 1384459:GL4_RS04240
uniprot id: A0A0A8K094
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1384459:GL4 RS03450
gene id: 1384459:GL4_RS03450
uniprot id: A0A0A8JZC9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1384459:GL4 RS13245
gene id: 1384459:GL4_RS13245
uniprot id: A0A0A8K5T3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1384459:GL4 RS08390
gene id: 1384459:GL4_RS08390
uniprot id: A0A0A8K5A8
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1384459:GL4 RS11620
gene id: 1384459:GL4_RS11620
uniprot id: A0A0A8K4G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1384459:GL4 RS13400
gene id: 1384459:GL4_RS13400
uniprot id: A0A0A8K6N8
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1384459:GL4 RS00780
gene id: 1384459:GL4_RS00780
uniprot id: A0A0A8JZ62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

1384459:GL4 RS15865
gene id: 1384459:GL4_RS15865
uniprot id: A0A0A8K6X5
names: Similarity
messages: Belongs to the aspartokinase family.

1384459:GL4 RS16925
gene id: 1384459:GL4_RS16925
uniprot id: A0A0A8K6Z9
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1384459:GL4 RS07620
gene id: 1384459:GL4_RS07620
uniprot id: A0A0A8K292
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1384459:GL4 RS02250
gene id: 1384459:GL4_RS02250
uniprot id: A0A0A8JZU3
names: Similarity
messages: Belongs to the UPF0102 family.

1384459:GL4 RS10370
gene id: 1384459:GL4_RS10370
uniprot id: A0A0A8K461
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1384459:GL4 RS06670
gene id: 1384459:GL4_RS06670
uniprot id: A0A0A8K1N5
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1384459:GL4 RS00485
gene id: 1384459:GL4_RS00485
uniprot id: A0A0A8JYA0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

1384459:GL4 RS01205
gene id: 1384459:GL4_RS01205
uniprot id: A0A0A8K145
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1384459:GL4 RS01510
gene id: 1384459:GL4_RS01510
uniprot id: A0A0A8JZK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1384459:GL4 RS14890
gene id: 1384459:GL4_RS14890
uniprot id: A0A0A8K6V0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1384459:GL4 RS15645
gene id: 1384459:GL4_RS15645
uniprot id: A0A0A8K7Y6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1384459:GL4 RS10760
gene id: 1384459:GL4_RS10760
uniprot id: A0A0A8K6N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1384459:GL4 RS02735
gene id: 1384459:GL4_RS02735
uniprot id: A0A0A8JZ01
names: Similarity
messages: Belongs to the thioredoxin family.

1384459:GL4 RS14570
gene id: 1384459:GL4_RS14570
uniprot id: A0A0A8K8W5
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1384459:GL4 RS11110
gene id: 1384459:GL4_RS11110
uniprot id: A0A0A8K4K0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1384459:GL4 RS10145
gene id: 1384459:GL4_RS10145
uniprot id: A0A0A8K3Q0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.

1384459:GL4 RS13350
gene id: 1384459:GL4_RS13350
uniprot id: A0A0A8K6M5
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1384459:GL4 RS10115
gene id: 1384459:GL4_RS10115
uniprot id: A0A0A8K695
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Cytoplasm
messages: Homodimer.

1384459:GL4 RS10135
gene id: 1384459:GL4_RS10135
uniprot id: A0A0A8K3K9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1384459:GL4 RS07605
gene id: 1384459:GL4_RS07605
uniprot id: A0A0A8K3B0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1384459:GL4 RS07630
gene id: 1384459:GL4_RS07630
uniprot id: A0A0A8K3B7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1384459:GL4 RS02720
gene id: 1384459:GL4_RS02720
uniprot id: A0A0A8JZN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1384459:GL4 RS01595
gene id: 1384459:GL4_RS01595
uniprot id: A0A0A8JZE7
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

1384459:GL4 RS07650
gene id: 1384459:GL4_RS07650
uniprot id: A0A0A8K2N3
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1384459:GL4 RS04865
gene id: 1384459:GL4_RS04865
uniprot id: A0A0A8K0P3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1384459:GL4 RS09760
gene id: 1384459:GL4_RS09760
uniprot id: A0A0A8K4K1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1384459:GL4 RS09050
gene id: 1384459:GL4_RS09050
uniprot id: A0A0A8K475
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1384459:GL4 RS04400
gene id: 1384459:GL4_RS04400
uniprot id: A0A0A8K330
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1384459:GL4 RS04310
gene id: 1384459:GL4_RS04310
uniprot id: A0A0A8K0B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1384459:GL4 RS00295
gene id: 1384459:GL4_RS00295
uniprot id: A0A0A8JY69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1384459:GL4 RS01470
gene id: 1384459:GL4_RS01470
uniprot id: A0A0A8K1A8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1384459:GL4 RS12165
gene id: 1384459:GL4_RS12165
uniprot id: A0A0A8K4T5
names: Function
names: Similarity
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.

1384459:GL4 RS04980
gene id: 1384459:GL4_RS04980
uniprot id: A0A0A8K3C3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1384459:GL4 RS04870
gene id: 1384459:GL4_RS04870
uniprot id: A0A0A8K123
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1384459:GL4 RS12945
gene id: 1384459:GL4_RS12945
uniprot id: A0A0A8K7X9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1384459:GL4 RS11365
gene id: 1384459:GL4_RS11365
uniprot id: A0A0A8K719
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1384459:GL4 RS10590
gene id: 1384459:GL4_RS10590
uniprot id: A0A0A8K505
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1384459:GL4 RS12970
gene id: 1384459:GL4_RS12970
uniprot id: A0A0A8K7Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1384459:GL4 RS14580
gene id: 1384459:GL4_RS14580
uniprot id: A0A0A8K6Q4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1384459:GL4 RS06780
gene id: 1384459:GL4_RS06780
uniprot id: A0A0A8K1N7
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS10525
gene id: 1384459:GL4_RS10525
uniprot id: A0A0A8K3T4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1384459:GL4 RS13065
gene id: 1384459:GL4_RS13065
uniprot id: A0A0A8K6G6
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1384459:GL4 RS02620
gene id: 1384459:GL4_RS02620
uniprot id: A0A0A8K1Y0
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1384459:GL4 RS00035
gene id: 1384459:GL4_RS00035
uniprot id: A0A0A8JYR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1384459:GL4 RS09735
gene id: 1384459:GL4_RS09735
uniprot id: A0A0A8K4J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1384459:GL4 RS01365
gene id: 1384459:GL4_RS01365
uniprot id: A0A0A8JY73
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1384459:GL4 RS00445
gene id: 1384459:GL4_RS00445
uniprot id: A0A0A8JY92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.
messages: Cytoplasm
messages: Homodimer.

1384459:GL4 RS11805
gene id: 1384459:GL4_RS11805
uniprot id: A0A0A8K4S6
names: Similarity
messages: Belongs to the UPF0178 family.

1384459:GL4 RS07775
gene id: 1384459:GL4_RS07775
uniprot id: A0A0A8K3E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1384459:GL4 RS03870
gene id: 1384459:GL4_RS03870
uniprot id: A0A0A8K0C5
names: Function
names: Similarity
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.

1384459:GL4 RS11210
gene id: 1384459:GL4_RS11210
uniprot id: A0A0A8K4M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1384459:GL4 RS14915
gene id: 1384459:GL4_RS14915
uniprot id: A0A0A8K6V5
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1384459:GL4 RS12020
gene id: 1384459:GL4_RS12020
uniprot id: A0A0A8K4R4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Maintains high levels of reduced glutathione.

1384459:GL4 RS11760
gene id: 1384459:GL4_RS11760
uniprot id: A0A0A8K4Q6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1384459:GL4 RS11220
gene id: 1384459:GL4_RS11220
uniprot id: A0A0A8K488
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1384459:GL4 RS05220
gene id: 1384459:GL4_RS05220
uniprot id: A0A0A8K0P1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1384459:GL4 RS03990
gene id: 1384459:GL4_RS03990
uniprot id: A0A0A8K0F6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1384459:GL4 RS00415
gene id: 1384459:GL4_RS00415
uniprot id: A0A0A8K0M4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1384459:GL4 RS04260
gene id: 1384459:GL4_RS04260
uniprot id: A0A0A8K2X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1384459:GL4 RS06585
gene id: 1384459:GL4_RS06585
uniprot id: A0A0A8K1I0
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1384459:GL4 RS01820
gene id: 1384459:GL4_RS01820
uniprot id: A0A0A8JZK3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1384459:GL4 RS07200
gene id: 1384459:GL4_RS07200
uniprot id: A0A0A8K220
names: Function
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1384459:GL4 RS09770
gene id: 1384459:GL4_RS09770
uniprot id: A0A0A8K636
names: Similarity
messages: Belongs to the FBPase class 2 family.

1384459:GL4 RS09105
gene id: 1384459:GL4_RS09105
uniprot id: A0A0A8K2Z8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1384459:GL4 RS13340
gene id: 1384459:GL4_RS13340
uniprot id: A0A0A8K5J9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1384459:GL4 RS02300
gene id: 1384459:GL4_RS02300
uniprot id: A0A0A8JZV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1384459:GL4 RS06590
gene id: 1384459:GL4_RS06590
uniprot id: A0A0A8K4A4
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1384459:GL4 RS07935
gene id: 1384459:GL4_RS07935
uniprot id: A0A0A8K3I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1384459:GL4 RS10820
gene id: 1384459:GL4_RS10820
uniprot id: A0A0A8K553
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1384459:GL4 RS14510
gene id: 1384459:GL4_RS14510
uniprot id: A0A0A8K6P3
names: Similarity
messages: Belongs to the DinB family.

1384459:GL4 RS03595
gene id: 1384459:GL4_RS03595
uniprot id: A0A0A8K2I3
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS16150
gene id: 1384459:GL4_RS16150
uniprot id: A0A0A8K7G6
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1384459:GL4 RS14060
gene id: 1384459:GL4_RS14060
uniprot id: A0A0A8K8L8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1384459:GL4 RS01555
gene id: 1384459:GL4_RS01555
uniprot id: A0A0A8JZL6
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1384459:GL4 RS00640
gene id: 1384459:GL4_RS00640
uniprot id: A0A0A8JYU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1384459:GL4 RS11690
gene id: 1384459:GL4_RS11690
uniprot id: A0A0A8K4L6
names: Similarity
messages: Belongs to the GppA/Ppx family.

1384459:GL4 RS12310
gene id: 1384459:GL4_RS12310
uniprot id: A0A0A8K611
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1384459:GL4 RS07655
gene id: 1384459:GL4_RS07655
uniprot id: A0A0A8K3C2
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1384459:GL4 RS01815
gene id: 1384459:GL4_RS01815
uniprot id: A0A0A8JZ45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1384459:GL4 RS06435
gene id: 1384459:GL4_RS06435
uniprot id: A0A0A8K2Q1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1384459:GL4 RS08795
gene id: 1384459:GL4_RS08795
uniprot id: A0A0A8K5J8
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1384459:GL4 RS13330
gene id: 1384459:GL4_RS13330
uniprot id: A0A0A8K5F8
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

1384459:GL4 RS11160
gene id: 1384459:GL4_RS11160
uniprot id: A0A0A8K4L2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1384459:GL4 RS07810
gene id: 1384459:GL4_RS07810
uniprot id: A0A0A8K280
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS03430
gene id: 1384459:GL4_RS03430
uniprot id: A0A0A8K2E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1384459:GL4 RS12980
gene id: 1384459:GL4_RS12980
uniprot id: A0A0A8K5P1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

1384459:GL4 RS06625
gene id: 1384459:GL4_RS06625
uniprot id: A0A0A8K221
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1384459:GL4 RS15100
gene id: 1384459:GL4_RS15100
uniprot id: A0A0A8K6G8
names: Similarity
messages: Belongs to the squalene monooxygenase family.

1384459:GL4 RS03760
gene id: 1384459:GL4_RS03760
uniprot id: A0A0A8K166
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1384459:GL4 RS04495
gene id: 1384459:GL4_RS04495
uniprot id: A0A0A8K0B1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1384459:GL4 RS14435
gene id: 1384459:GL4_RS14435
uniprot id: A0A0A8K693
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1384459:GL4 RS05720
gene id: 1384459:GL4_RS05720
uniprot id: A0A0A8K0Y5
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS16365
gene id: 1384459:GL4_RS16365
uniprot id: A0A0A8K799
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1384459:GL4 RS16375
gene id: 1384459:GL4_RS16375
uniprot id: A0A0A8K782
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1384459:GL4 RS06635
gene id: 1384459:GL4_RS06635
uniprot id: A0A0A8K1J0
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1384459:GL4 RS05450
gene id: 1384459:GL4_RS05450
uniprot id: A0A0A8K1B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1384459:GL4 RS08020
gene id: 1384459:GL4_RS08020
uniprot id: A0A0A8K525
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1384459:GL4 RS14475
gene id: 1384459:GL4_RS14475
uniprot id: A0A0A8K8V2
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS04025
gene id: 1384459:GL4_RS04025
uniprot id: A0A0A8JZQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1384459:GL4 RS01585
gene id: 1384459:GL4_RS01585
uniprot id: A0A0A8K1D5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1384459:GL4 RS02920
gene id: 1384459:GL4_RS02920
uniprot id: A0A0A8K005
names: Similarity
messages: Belongs to the UPF0335 family.

1384459:GL4 RS00565
gene id: 1384459:GL4_RS00565
uniprot id: A0A0A8JYT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1384459:GL4 RS03295
gene id: 1384459:GL4_RS03295
uniprot id: A0A0A8K036
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1384459:GL4 RS08680
gene id: 1384459:GL4_RS08680
uniprot id: A0A0A8K5H5
names: Similarity
messages: Belongs to the FwdC/FmdC family.

1384459:GL4 RS03845
gene id: 1384459:GL4_RS03845
uniprot id: A0A0A8K035
names: Similarity
messages: Belongs to the glutamine synthetase family.

1384459:GL4 RS02305
gene id: 1384459:GL4_RS02305
uniprot id: A0A0A8K0B3
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1384459:GL4 RS01965
gene id: 1384459:GL4_RS01965
uniprot id: A0A0A8JZA8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1384459:GL4 RS07740
gene id: 1384459:GL4_RS07740
uniprot id: A0A0A8K2B2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1384459:GL4 RS07600
gene id: 1384459:GL4_RS07600
uniprot id: A0A0A8K2M6
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS13440
gene id: 1384459:GL4_RS13440
uniprot id: A0A0A8K5W7
names: Similarity
messages: Belongs to the ArsC family.

1384459:GL4 RS11090
gene id: 1384459:GL4_RS11090
uniprot id: A0A0A8K5C4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1384459:GL4 RS04350
gene id: 1384459:GL4_RS04350
uniprot id: A0A0A8K314
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1384459:GL4 RS16540
gene id: 1384459:GL4_RS16540
uniprot id: A0A0A8K2U9
names: Similarity
messages: Belongs to the autoinducer synthase family.

1384459:GL4 RS01560
gene id: 1384459:GL4_RS01560
uniprot id: A0A0A8JYA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1384459:GL4 RS08865
gene id: 1384459:GL4_RS08865
uniprot id: A0A0A8K2V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1384459:GL4 RS03685
gene id: 1384459:GL4_RS03685
uniprot id: A0A0A8K149
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1384459:GL4 RS03625
gene id: 1384459:GL4_RS03625
uniprot id: A0A0A8K019
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

1384459:GL4 RS09880
gene id: 1384459:GL4_RS09880
uniprot id: A0A0A8K652
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1384459:GL4 RS10550
gene id: 1384459:GL4_RS10550
uniprot id: A0A0A8K3U1
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS00535
gene id: 1384459:GL4_RS00535
uniprot id: A0A0A8JYA9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1384459:GL4 RS10210
gene id: 1384459:GL4_RS10210
uniprot id: A0A0A8K3M1
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS07400
gene id: 1384459:GL4_RS07400
uniprot id: A0A0A8K4Q3
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS11820
gene id: 1384459:GL4_RS11820
uniprot id: A0A0A8K4N8
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1384459:GL4 RS03495
gene id: 1384459:GL4_RS03495
uniprot id: A0A0A8JZD9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1384459:GL4 RS03855
gene id: 1384459:GL4_RS03855
uniprot id: A0A0A8JZM0
names: Similarity
messages: Belongs to the glutamine synthetase family.

1384459:GL4 RS04505
gene id: 1384459:GL4_RS04505
uniprot id: A0A0A8K0I6
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1384459:GL4 RS16145
gene id: 1384459:GL4_RS16145
uniprot id: A0A0A8K757
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS03630
gene id: 1384459:GL4_RS03630
uniprot id: A0A0A8K066
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1384459:GL4 RS07665
gene id: 1384459:GL4_RS07665
uniprot id: A0A0A8K299
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1384459:GL4 RS02525
gene id: 1384459:GL4_RS02525
uniprot id: A0A0A8K1W1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1384459:GL4 RS05845
gene id: 1384459:GL4_RS05845
uniprot id: A0A0A8K168
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1384459:GL4 RS04705
gene id: 1384459:GL4_RS04705
uniprot id: A0A0A8K0Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1384459:GL4 RS16490
gene id: 1384459:GL4_RS16490
uniprot id: A0A0A8JZP8
names: Similarity
messages: Belongs to the YkuD family.

1384459:GL4 RS02295
gene id: 1384459:GL4_RS02295
uniprot id: A0A0A8JZF8
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

1384459:GL4 RS12880
gene id: 1384459:GL4_RS12880
uniprot id: A0A0A8K7W5
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1384459:GL4 RS04775
gene id: 1384459:GL4_RS04775
uniprot id: A0A0A8K107
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1384459:GL4 RS06505
gene id: 1384459:GL4_RS06505
uniprot id: A0A0A8K1G4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1384459:GL4 RS03405
gene id: 1384459:GL4_RS03405
uniprot id: A0A0A8K2D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1384459:GL4 RS08805
gene id: 1384459:GL4_RS08805
uniprot id: A0A0A8K389
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1384459:GL4 RS12395
gene id: 1384459:GL4_RS12395
uniprot id: A0A0A8K7L1
names: Similarity
messages: Belongs to the peptidase C40 family.

1384459:GL4 RS13240
gene id: 1384459:GL4_RS13240
uniprot id: A0A0A8K5I1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1384459:GL4 RS12895
gene id: 1384459:GL4_RS12895
uniprot id: A0A0A8K6D0
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1384459:GL4 RS01255
gene id: 1384459:GL4_RS01255
uniprot id: A0A0A8K156
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1384459:GL4 RS01145
gene id: 1384459:GL4_RS01145
uniprot id: A0A0A8JZD3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1384459:GL4 RS02285
gene id: 1384459:GL4_RS02285
uniprot id: A0A0A8JYR3
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1384459:GL4 RS00350
gene id: 1384459:GL4_RS00350
uniprot id: A0A0A8JYN4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cell inner membrane
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1384459:GL4 RS15870
gene id: 1384459:GL4_RS15870
uniprot id: A0A0A8K9D8
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1384459:GL4 RS07595
gene id: 1384459:GL4_RS07595
uniprot id: A0A0A8K287
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1384459:GL4 RS13180
gene id: 1384459:GL4_RS13180
uniprot id: A0A0A8K5C7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1384459:GL4 RS11225
gene id: 1384459:GL4_RS11225
uniprot id: A0A0A8K6Z3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1384459:GL4 RS03490
gene id: 1384459:GL4_RS03490
uniprot id: A0A0A8K104
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1384459:GL4 RS04050
gene id: 1384459:GL4_RS04050
uniprot id: A0A0A8JZQ7
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1384459:GL4 RS08685
gene id: 1384459:GL4_RS08685
uniprot id: A0A0A8K2V8
names: Function
messages: Acts on leucine, isoleucine and valine.

1384459:GL4 RS05680
gene id: 1384459:GL4_RS05680
uniprot id: A0A0A8K0X5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1384459:GL4 RS00560
gene id: 1384459:GL4_RS00560
uniprot id: A0A0A8JYB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1384459:GL4 RS10495
gene id: 1384459:GL4_RS10495
uniprot id: A0A0A8K4Y3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1384459:GL4 RS12585
gene id: 1384459:GL4_RS12585
uniprot id: A0A0A8K7Q0
names: Similarity
messages: Belongs to the peptidase S9A family.

1384459:GL4 RS01590
gene id: 1384459:GL4_RS01590
uniprot id: A0A0A8JYZ4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1384459:GL4 RS07590
gene id: 1384459:GL4_RS07590
uniprot id: A0A0A8K4T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1384459:GL4 RS08660
gene id: 1384459:GL4_RS08660
uniprot id: A0A0A8K2V2
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1384459:GL4 RS10000
gene id: 1384459:GL4_RS10000
uniprot id: A0A0A8K3I4
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1384459:GL4 RS16450
gene id: 1384459:GL4_RS16450
uniprot id: A0A0A8K0S8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1384459:GL4 RS02005
gene id: 1384459:GL4_RS02005
uniprot id: A0A0A8JYM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

1384459:GL4 RS08545
gene id: 1384459:GL4_RS08545
uniprot id: A0A0A8K3W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.
messages: Oligomer of 12 subunits arranged in the form of two hexameric ring.

1384459:GL4 RS05125
gene id: 1384459:GL4_RS05125
uniprot id: A0A0A8K0T4
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1384459:GL4 RS08015
gene id: 1384459:GL4_RS08015
uniprot id: A0A0A8K2B9
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS11750
gene id: 1384459:GL4_RS11750
uniprot id: A0A0A8K4L9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1384459:GL4 RS07675
gene id: 1384459:GL4_RS07675
uniprot id: A0A0A8K3D0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1384459:GL4 RS03420
gene id: 1384459:GL4_RS03420
uniprot id: A0A0A8K0Y6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1384459:GL4 RS14455
gene id: 1384459:GL4_RS14455
uniprot id: A0A0A8K696
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1384459:GL4 RS10560
gene id: 1384459:GL4_RS10560
uniprot id: A0A0A8K3Y5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1384459:GL4 RS00770
gene id: 1384459:GL4_RS00770
uniprot id: A0A0A8JYE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

1384459:GL4 RS00555
gene id: 1384459:GL4_RS00555
uniprot id: A0A0A8K0Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1384459:GL4 RS14550
gene id: 1384459:GL4_RS14550
uniprot id: A0A0A8K8W3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1384459:GL4 RS11080
gene id: 1384459:GL4_RS11080
uniprot id: A0A0A8K492
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1384459:GL4 RS06740
gene id: 1384459:GL4_RS06740
uniprot id: A0A0A8K1Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1384459:GL4 RS01505
gene id: 1384459:GL4_RS01505
uniprot id: A0A0A8JZC6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1384459:GL4 RS10770
gene id: 1384459:GL4_RS10770
uniprot id: A0A0A8K4D2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1384459:GL4 RS09120
gene id: 1384459:GL4_RS09120
uniprot id: A0A0A8K3H3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1384459:GL4 RS08340
gene id: 1384459:GL4_RS08340
uniprot id: A0A0A8K594
names: Similarity
messages: Belongs to the UPF0758 family.

1384459:GL4 RS10775
gene id: 1384459:GL4_RS10775
uniprot id: A0A0A8K543
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1384459:GL4 RS09395
gene id: 1384459:GL4_RS09395
uniprot id: A0A0A8K3R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1384459:GL4 RS00635
gene id: 1384459:GL4_RS00635
uniprot id: A0A0A8JYC7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1384459:GL4 RS03465
gene id: 1384459:GL4_RS03465
uniprot id: A0A0A8K049
names: Similarity
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.

1384459:GL4 RS05255
gene id: 1384459:GL4_RS05255
uniprot id: A0A0A8K3H7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1384459:GL4 RS09450
gene id: 1384459:GL4_RS09450
uniprot id: A0A0A8K4G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1384459:GL4 RS05765
gene id: 1384459:GL4_RS05765
uniprot id: A0A0A8K0Z7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1384459:GL4 RS07970
gene id: 1384459:GL4_RS07970
uniprot id: A0A0A8K517
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1384459:GL4 RS02730
gene id: 1384459:GL4_RS02730
uniprot id: A0A0A8K0J2
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

1384459:GL4 RS05885
gene id: 1384459:GL4_RS05885
uniprot id: A0A0A8K125
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1384459:GL4 RS12280
gene id: 1384459:GL4_RS12280
uniprot id: A0A0A8K5C5
names: Similarity
messages: Belongs to the ArsC family.

1384459:GL4 RS06080
gene id: 1384459:GL4_RS06080
uniprot id: A0A0A8K2G6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1384459:GL4 RS15220
gene id: 1384459:GL4_RS15220
uniprot id: A0A0A8K7P2
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS08025
gene id: 1384459:GL4_RS08025
uniprot id: A0A0A8K2G9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Could be part of an ABC transporter complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1384459:GL4 RS10950
gene id: 1384459:GL4_RS10950
uniprot id: A0A0A8K6T0
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.

1384459:GL4 RS00080
gene id: 1384459:GL4_RS00080
uniprot id: A0A0A8JYI7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1384459:GL4 RS15015
gene id: 1384459:GL4_RS15015
uniprot id: A0A0A8K6W9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1384459:GL4 RS10180
gene id: 1384459:GL4_RS10180
uniprot id: A0A0A8K4R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1384459:GL4 RS11735
gene id: 1384459:GL4_RS11735
uniprot id: A0A0A8K4N1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1384459:GL4 RS01100
gene id: 1384459:GL4_RS01100
uniprot id: A0A0A8JY18
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1384459:GL4 RS08700
gene id: 1384459:GL4_RS08700
uniprot id: A0A0A8K2S3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1384459:GL4 RS04725
gene id: 1384459:GL4_RS04725
uniprot id: A0A0A8K0M1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1384459:GL4 RS11170
gene id: 1384459:GL4_RS11170
uniprot id: A0A0A8K478
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1384459:GL4 RS14935
gene id: 1384459:GL4_RS14935
uniprot id: A0A0A8K6V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1384459:GL4 RS05025
gene id: 1384459:GL4_RS05025
uniprot id: A0A0A8K3D1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1384459:GL4 RS06530
gene id: 1384459:GL4_RS06530
uniprot id: A0A0A8K1H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1384459:GL4 RS00825
gene id: 1384459:GL4_RS00825
uniprot id: A0A0A8JZ71
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1384459:GL4 RS09460
gene id: 1384459:GL4_RS09460
uniprot id: A0A0A8K5Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1384459:GL4 RS10410
gene id: 1384459:GL4_RS10410
uniprot id: A0A0A8K6F8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1384459:GL4 RS03330
gene id: 1384459:GL4_RS03330
uniprot id: A0A0A8K2C1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1384459:GL4 RS04215
gene id: 1384459:GL4_RS04215
uniprot id: A0A0A8K087
names: Similarity
messages: Belongs to the ArsC family.

1384459:GL4 RS12875
gene id: 1384459:GL4_RS12875
uniprot id: A0A0A8K563
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1384459:GL4 RS01230
gene id: 1384459:GL4_RS01230
uniprot id: A0A0A8K151
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1384459:GL4 RS04070
gene id: 1384459:GL4_RS04070
uniprot id: A0A0A8K1D6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1384459:GL4 RS15300
gene id: 1384459:GL4_RS15300
uniprot id: A0A0A8K6K3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1384459:GL4 RS16005
gene id: 1384459:GL4_RS16005
uniprot id: A0A0A8K7D2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1384459:GL4 RS04660
gene id: 1384459:GL4_RS04660
uniprot id: A0A0A8K1P3
names: Similarity
messages: Belongs to the GARS family.

1384459:GL4 RS09070
gene id: 1384459:GL4_RS09070
uniprot id: A0A0A8K3F9
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1384459:GL4 RS08840
gene id: 1384459:GL4_RS08840
uniprot id: A0A0A8K2U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1384459:GL4 RS11655
gene id: 1384459:GL4_RS11655
uniprot id: A0A0A8K4H0
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS15065
gene id: 1384459:GL4_RS15065
uniprot id: A0A0A8K6X8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1384459:GL4 RS03590
gene id: 1384459:GL4_RS03590
uniprot id: A0A0A8JZG0
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS03305
gene id: 1384459:GL4_RS03305
uniprot id: A0A0A8K2B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1384459:GL4 RS10075
gene id: 1384459:GL4_RS10075
uniprot id: A0A0A8K415
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1384459:GL4 RS05520
gene id: 1384459:GL4_RS05520
uniprot id: A0A0A8K247
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1384459:GL4 RS03975
gene id: 1384459:GL4_RS03975
uniprot id: A0A0A8JZP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1384459:GL4 RS10680
gene id: 1384459:GL4_RS10680
uniprot id: A0A0A8K527
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1384459:GL4 RS10205
gene id: 1384459:GL4_RS10205
uniprot id: A0A0A8K4R8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1384459:GL4 RS16350
gene id: 1384459:GL4_RS16350
uniprot id: A0A0A8K8E3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1384459:GL4 RS12785
gene id: 1384459:GL4_RS12785
uniprot id: A0A0A8K7U5
names: Similarity
messages: Belongs to the RNase T2 family.

1384459:GL4 RS14495
gene id: 1384459:GL4_RS14495
uniprot id: A0A0A8K661
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1384459:GL4 RS12930
gene id: 1384459:GL4_RS12930
uniprot id: A0A0A8K5C0
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS12735
gene id: 1384459:GL4_RS12735
uniprot id: A0A0A8K537
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS08225
gene id: 1384459:GL4_RS08225
uniprot id: A0A0A8K2X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1384459:GL4 RS13115
gene id: 1384459:GL4_RS13115
uniprot id: A0A0A8K5F6
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1384459:GL4 RS05425
gene id: 1384459:GL4_RS05425
uniprot id: A0A0A8K1A9
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family.

1384459:GL4 RS07855
gene id: 1384459:GL4_RS07855
uniprot id: A0A0A8K2R6
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS13160
gene id: 1384459:GL4_RS13160
uniprot id: A0A0A8K823
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1384459:GL4 RS01545
gene id: 1384459:GL4_RS01545
uniprot id: A0A0A8JYY2
names: Similarity
messages: Belongs to the Tim44 family.

1384459:GL4 RS10005
gene id: 1384459:GL4_RS10005
uniprot id: A0A0A8K674
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1384459:GL4 RS06320
gene id: 1384459:GL4_RS06320
uniprot id: A0A0A8K1S8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Cell membrane
messages: Membrane

1384459:GL4 RS03435
gene id: 1384459:GL4_RS03435
uniprot id: A0A0A8K001
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1384459:GL4 RS16305
gene id: 1384459:GL4_RS16305
uniprot id: A0A0A8K8D3
names: Function
names: Similarity
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.

1384459:GL4 RS10090
gene id: 1384459:GL4_RS10090
uniprot id: A0A0A8K689
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1384459:GL4 RS09425
gene id: 1384459:GL4_RS09425
uniprot id: A0A0A8K4F6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1384459:GL4 RS00435
gene id: 1384459:GL4_RS00435
uniprot id: A0A0A8JXP7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1384459:GL4 RS09175
gene id: 1384459:GL4_RS09175
uniprot id: A0A0A8K4A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1384459:GL4 RS03740
gene id: 1384459:GL4_RS03740
uniprot id: A0A0A8JZJ1
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1384459:GL4 RS00170
gene id: 1384459:GL4_RS00170
uniprot id: A0A0A8JXJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1384459:GL4 RS13430
gene id: 1384459:GL4_RS13430
uniprot id: A0A0A8K887
names: Similarity
messages: Belongs to the PhzF family.

1384459:GL4 RS02000
gene id: 1384459:GL4_RS02000
uniprot id: A0A0A8K065
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1384459:GL4 RS13495
gene id: 1384459:GL4_RS13495
uniprot id: A0A0A8K8A4
names: Function
names: Similarity
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.

1384459:GL4 RS08745
gene id: 1384459:GL4_RS08745
uniprot id: A0A0A8K379
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1384459:GL4 RS10170
gene id: 1384459:GL4_RS10170
uniprot id: A0A0A8K3Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell inner membrane
messages: Membrane

1384459:GL4 RS02290
gene id: 1384459:GL4_RS02290
uniprot id: A0A0A8K1S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1384459:GL4 RS16090
gene id: 1384459:GL4_RS16090
uniprot id: A0A0A8K723
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1384459:GL4 RS15415
gene id: 1384459:GL4_RS15415
uniprot id: A0A0A8K7T8
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1384459:GL4 RS07570
gene id: 1384459:GL4_RS07570
uniprot id: A0A0A8K283
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS12820
gene id: 1384459:GL4_RS12820
uniprot id: A0A0A8K5L2
names: Similarity
messages: Belongs to the glutamate synthase family.

1384459:GL4 RS03615
gene id: 1384459:GL4_RS03615
uniprot id: A0A0A8JZG4
names: Similarity
messages: Belongs to the peptidase C40 family.

1384459:GL4 RS11670
gene id: 1384459:GL4_RS11670
uniprot id: A0A0A8K4Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

1384459:GL4 RS11525
gene id: 1384459:GL4_RS11525
uniprot id: A0A0A8K753
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

1384459:GL4 RS10815
gene id: 1384459:GL4_RS10815
uniprot id: A0A0A8K4E0
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1384459:GL4 RS11930
gene id: 1384459:GL4_RS11930
uniprot id: A0A0A8K7E6
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Proposed to provide activated sulfate for transfer to Nod factor. ATP sulfurylase may be the GTPase, regulating ATP sulfurylase activity.
messages: Sulfate-activating enzymes, NodP and NodQ, may be physically associated.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1384459:GL4 RS16085
gene id: 1384459:GL4_RS16085
uniprot id: A0A0A8K885
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1384459:GL4 RS15840
gene id: 1384459:GL4_RS15840
uniprot id: A0A0A8K6X0
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1384459:GL4 RS00620
gene id: 1384459:GL4_RS00620
uniprot id: A0A0A8JZ26
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1384459:GL4 RS16335
gene id: 1384459:GL4_RS16335
uniprot id: A0A0A8K9M1
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

1384459:GL4 RS16195
gene id: 1384459:GL4_RS16195
uniprot id: A0A0A8K768
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1384459:GL4 RS01735
gene id: 1384459:GL4_RS01735
uniprot id: A0A0A8K1G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1384459:GL4 RS12030
gene id: 1384459:GL4_RS12030
uniprot id: A0A0A8K4W0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1384459:GL4 RS10500
gene id: 1384459:GL4_RS10500
uniprot id: A0A0A8K3S9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1384459:GL4 RS05070
gene id: 1384459:GL4_RS05070
uniprot id: A0A0A8K0L4
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS11615
gene id: 1384459:GL4_RS11615
uniprot id: A0A0A8K5P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1384459:GL4 RS11130
gene id: 1384459:GL4_RS11130
uniprot id: A0A0A8K4A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1384459:GL4 RS14910
gene id: 1384459:GL4_RS14910
uniprot id: A0A0A8K6H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1384459:GL4 RS08520
gene id: 1384459:GL4_RS08520
uniprot id: A0A0A8K3V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1384459:GL4 RS10120
gene id: 1384459:GL4_RS10120
uniprot id: A0A0A8K3P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1384459:GL4 RS11695
gene id: 1384459:GL4_RS11695
uniprot id: A0A0A8K502
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1384459:GL4 RS11960
gene id: 1384459:GL4_RS11960
uniprot id: A0A0A8K4V0
names: Similarity
messages: Belongs to the LOG family.

1384459:GL4 RS01410
gene id: 1384459:GL4_RS01410
uniprot id: A0A0A8JZI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1384459:GL4 RS15235
gene id: 1384459:GL4_RS15235
uniprot id: A0A0A8K6M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1384459:GL4 RS17610
gene id: 1384459:GL4_RS17610
uniprot id: A0A0A8K6L7
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS02795
gene id: 1384459:GL4_RS02795
uniprot id: A0A0A8JZZ8
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1384459:GL4 RS00340
gene id: 1384459:GL4_RS00340
uniprot id: A0A0A8K0L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1384459:GL4 RS01060
gene id: 1384459:GL4_RS01060
uniprot id: A0A0A8JYK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1384459:GL4 RS15145
gene id: 1384459:GL4_RS15145
uniprot id: A0A0A8K6Y9
names: Similarity
messages: Belongs to the UPF0276 family.

1384459:GL4 RS11165
gene id: 1384459:GL4_RS11165
uniprot id: A0A0A8K5E2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1384459:GL4 RS01970
gene id: 1384459:GL4_RS01970
uniprot id: A0A0A8JZQ6
names: Similarity
messages: Belongs to the CobH/CbiC family.

1384459:GL4 RS15650
gene id: 1384459:GL4_RS15650
uniprot id: A0A0A8K6T3
names: Similarity
messages: Belongs to the GcvT family.

1384459:GL4 RS12160
gene id: 1384459:GL4_RS12160
uniprot id: A0A0A8K5Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1384459:GL4 RS09950
gene id: 1384459:GL4_RS09950
uniprot id: A0A0A8K3H4
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS05225
gene id: 1384459:GL4_RS05225
uniprot id: A0A0A8K3H2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-55 and Arg-58) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1384459:GL4 RS15315
gene id: 1384459:GL4_RS15315
uniprot id: A0A0A8K715
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

1384459:GL4 RS11195
gene id: 1384459:GL4_RS11195
uniprot id: A0A0A8K483
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1384459:GL4 RS12845
gene id: 1384459:GL4_RS12845
uniprot id: A0A0A8K5L7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1384459:GL4 RS09740
gene id: 1384459:GL4_RS09740
uniprot id: A0A0A8K3D8
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1384459:GL4 RS12685
gene id: 1384459:GL4_RS12685
uniprot id: A0A0A8K566
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

1384459:GL4 RS01465
gene id: 1384459:GL4_RS01465
uniprot id: A0A0A8JY89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1384459:GL4 RS02200
gene id: 1384459:GL4_RS02200
uniprot id: A0A0A8JZT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1384459:GL4 RS02220
gene id: 1384459:GL4_RS02220
uniprot id: A0A0A8JZE4
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1384459:GL4 RS13150
gene id: 1384459:GL4_RS13150
uniprot id: A0A0A8K6I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1384459:GL4 RS08465
gene id: 1384459:GL4_RS08465
uniprot id: A0A0A8K321
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1384459:GL4 RS11035
gene id: 1384459:GL4_RS11035
uniprot id: A0A0A8K4I1
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1384459:GL4 RS03505
gene id: 1384459:GL4_RS03505
uniprot id: A0A0A8K008
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OprB family.
messages: Cell outer membrane

1384459:GL4 RS02445
gene id: 1384459:GL4_RS02445
uniprot id: A0A0A8K0D9
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS07560
gene id: 1384459:GL4_RS07560
uniprot id: A0A0A8K235
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1384459:GL4 RS08935
gene id: 1384459:GL4_RS08935
uniprot id: A0A0A8K447
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1384459:GL4 RS08275
gene id: 1384459:GL4_RS08275
uniprot id: A0A0A8K2Y6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1384459:GL4 RS04570
gene id: 1384459:GL4_RS04570
uniprot id: A0A0A8K0C6
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Has an organic peroxide-dependent peroxidase activity.

1384459:GL4 RS05500
gene id: 1384459:GL4_RS05500
uniprot id: A0A0A8K0T9
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1384459:GL4 RS15750
gene id: 1384459:GL4_RS15750
uniprot id: A0A0A8K6Y3
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS14815
gene id: 1384459:GL4_RS14815
uniprot id: A0A0A8K8Z5
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1384459:GL4 RS06705
gene id: 1384459:GL4_RS06705
uniprot id: A0A0A8K2V7
names: Similarity
messages: Belongs to the peptidase S13 family.

1384459:GL4 RS11600
gene id: 1384459:GL4_RS11600
uniprot id: A0A0A8K770
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1384459:GL4 RS06000
gene id: 1384459:GL4_RS06000
uniprot id: A0A0A8K3W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

1384459:GL4 RS02190
gene id: 1384459:GL4_RS02190
uniprot id: A0A0A8K1Q8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1384459:GL4 RS07420
gene id: 1384459:GL4_RS07420
uniprot id: A0A0A8K4Q7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1384459:GL4 RS02695
gene id: 1384459:GL4_RS02695
uniprot id: A0A0A8JZN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1384459:GL4 RS04860
gene id: 1384459:GL4_RS04860
uniprot id: A0A0A8K3A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1384459:GL4 RS16080
gene id: 1384459:GL4_RS16080
uniprot id: A0A0A8K7E9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1384459:GL4 RS11190
gene id: 1384459:GL4_RS11190
uniprot id: A0A0A8K5E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1384459:GL4 RS12710
gene id: 1384459:GL4_RS12710
uniprot id: A0A0A8K570
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1384459:GL4 RS11065
gene id: 1384459:GL4_RS11065
uniprot id: A0A0A8K5B8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1384459:GL4 RS05075
gene id: 1384459:GL4_RS05075
uniprot id: A0A0A8K3E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1384459:GL4 RS13010
gene id: 1384459:GL4_RS13010
uniprot id: A0A0A8K5P5
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1384459:GL4 RS09900
gene id: 1384459:GL4_RS09900
uniprot id: A0A0A8K3G4
names: Function
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

1384459:GL4 RS01645
gene id: 1384459:GL4_RS01645
uniprot id: A0A0A8JZG5
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1384459:GL4 RS11180
gene id: 1384459:GL4_RS11180
uniprot id: A0A0A8K4B1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1384459:GL4 RS16345
gene id: 1384459:GL4_RS16345
uniprot id: A0A0A8K7L4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1384459:GL4 RS11965
gene id: 1384459:GL4_RS11965
uniprot id: A0A0A8K578
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1384459:GL4 RS09075
gene id: 1384459:GL4_RS09075
uniprot id: A0A0A8K480
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1384459:GL4 RS10140
gene id: 1384459:GL4_RS10140
uniprot id: A0A0A8K6A0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1384459:GL4 RS10510
gene id: 1384459:GL4_RS10510
uniprot id: A0A0A8K3X5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1384459:GL4 RS01685
gene id: 1384459:GL4_RS01685
uniprot id: A0A0A8K1F6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.
messages: In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP. P-II-UMP allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme. Conversely, in nitrogen excess P-II is deuridylated and promotes the adenylation of GS. P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is uridylylated to P-II-UMP, these events are reversed.

1384459:GL4 RS00135
gene id: 1384459:GL4_RS00135
uniprot id: A0A0A8JYJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1384459:GL4 RS08400
gene id: 1384459:GL4_RS08400
uniprot id: A0A0A8K306
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1384459:GL4 RS04625
gene id: 1384459:GL4_RS04625
uniprot id: A0A0A8K0K6
names: Similarity
messages: Belongs to the peptidase M16 family.

1384459:GL4 RS10385
gene id: 1384459:GL4_RS10385
uniprot id: A0A0A8K6F3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1384459:GL4 RS08900
gene id: 1384459:GL4_RS08900
uniprot id: A0A0A8K2Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1384459:GL4 RS02565
gene id: 1384459:GL4_RS02565
uniprot id: A0A0A8K0F9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1384459:GL4 RS05195
gene id: 1384459:GL4_RS05195
uniprot id: A0A0A8K0N7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1384459:GL4 RS08180
gene id: 1384459:GL4_RS08180
uniprot id: A0A0A8K3N0
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS06480
gene id: 1384459:GL4_RS06480
uniprot id: A0A0A8K2R1
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1384459:GL4 RS06515
gene id: 1384459:GL4_RS06515
uniprot id: A0A0A8K1K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1384459:GL4 RS02435
gene id: 1384459:GL4_RS02435
uniprot id: A0A0A8JZI0
names: Similarity
messages: Belongs to the YkuD family.

1384459:GL4 RS10305
gene id: 1384459:GL4_RS10305
uniprot id: A0A0A8K3N7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.

1384459:GL4 RS10465
gene id: 1384459:GL4_RS10465
uniprot id: A0A0A8K481
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1384459:GL4 RS00075
gene id: 1384459:GL4_RS00075
uniprot id: A0A0A8JY36
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1384459:GL4 RS07770
gene id: 1384459:GL4_RS07770
uniprot id: A0A0A8K2Q3
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1384459:GL4 RS14240
gene id: 1384459:GL4_RS14240
uniprot id: A0A0A8K662
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1384459:GL4 RS03290
gene id: 1384459:GL4_RS03290
uniprot id: A0A0A8K2A8
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1384459:GL4 RS02345
gene id: 1384459:GL4_RS02345
uniprot id: A0A0A8K1S9
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS07880
gene id: 1384459:GL4_RS07880
uniprot id: A0A0A8K2S0
names: Function
messages: Acts on leucine, isoleucine and valine.

1384459:GL4 RS00545
gene id: 1384459:GL4_RS00545
uniprot id: A0A0A8JZ12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1384459:GL4 RS01925
gene id: 1384459:GL4_RS01925
uniprot id: A0A0A8K059
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1384459:GL4 RS05405
gene id: 1384459:GL4_RS05405
uniprot id: A0A0A8K226
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

1384459:GL4 RS10330
gene id: 1384459:GL4_RS10330
uniprot id: A0A0A8K3P2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1384459:GL4 RS12575
gene id: 1384459:GL4_RS12575
uniprot id: A0A0A8K654
names: Similarity
messages: Belongs to the ros/MucR family.

1384459:GL4 RS06390
gene id: 1384459:GL4_RS06390
uniprot id: A0A0A8K1D8
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1384459:GL4 RS01580
gene id: 1384459:GL4_RS01580
uniprot id: A0A0A8JYB2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1384459:GL4 RS14540
gene id: 1384459:GL4_RS14540
uniprot id: A0A0A8K7D3
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1384459:GL4 RS05535
gene id: 1384459:GL4_RS05535
uniprot id: A0A0A8K253
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1384459:GL4 RS10430
gene id: 1384459:GL4_RS10430
uniprot id: A0A0A8K3R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1384459:GL4 RS06025
gene id: 1384459:GL4_RS06025
uniprot id: A0A0A8K3X4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1384459:GL4 RS00450
gene id: 1384459:GL4_RS00450
uniprot id: A0A0A8JYZ3
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS17000
gene id: 1384459:GL4_RS17000
uniprot id: A0A0A8K751
names: Similarity
messages: Belongs to the AHA1 family.

1384459:GL4 RS09570
gene id: 1384459:GL4_RS09570
uniprot id: A0A0A8K3U0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

1384459:GL4 RS05055
gene id: 1384459:GL4_RS05055
uniprot id: A0A0A8K0S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1384459:GL4 RS01660
gene id: 1384459:GL4_RS01660
uniprot id: A0A0A8K1F0
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1384459:GL4 RS03415
gene id: 1384459:GL4_RS03415
uniprot id: A0A0A8K045
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1384459:GL4 RS04455
gene id: 1384459:GL4_RS04455
uniprot id: A0A0A8K341
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1384459:GL4 RS12265
gene id: 1384459:GL4_RS12265
uniprot id: A0A0A8K4V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1384459:GL4 RS12810
gene id: 1384459:GL4_RS12810
uniprot id: A0A0A8K7V2
names: Subcellular Location Annotation
messages: Membrane

1384459:GL4 RS02010
gene id: 1384459:GL4_RS02010
uniprot id: A0A0A8K1N4
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.