1379270:GEMMAAP RS14740
gene id: 1379270:GEMMAAP_RS14740
uniprot id: A0A143BMP1
names: Similarity
messages: Belongs to the creatininase superfamily.

1379270:GEMMAAP RS18415
gene id: 1379270:GEMMAAP_RS18415
uniprot id: A0A143BNX2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1379270:GEMMAAP RS16040
gene id: 1379270:GEMMAAP_RS16040
uniprot id: A0A143BN46
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1379270:GEMMAAP RS00795
gene id: 1379270:GEMMAAP_RS00795
uniprot id: A0A143BFH8
names: Similarity
messages: Belongs to the AHA1 family.

1379270:GEMMAAP RS15980
gene id: 1379270:GEMMAAP_RS15980
uniprot id: A0A143BMZ9
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS09310
gene id: 1379270:GEMMAAP_RS09310
uniprot id: A0A143BIW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1379270:GEMMAAP RS17925
gene id: 1379270:GEMMAAP_RS17925
uniprot id: A0A143BNN2
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1379270:GEMMAAP RS12605
gene id: 1379270:GEMMAAP_RS12605
uniprot id: A0A143BLK8
names: Similarity
messages: Belongs to the Lgt family.

1379270:GEMMAAP RS16555
gene id: 1379270:GEMMAAP_RS16555
uniprot id: A0A143BMW3
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1379270:GEMMAAP RS06830
gene id: 1379270:GEMMAAP_RS06830
uniprot id: A0A143BJ99
names: Similarity
messages: Belongs to the UPF0234 family.

1379270:GEMMAAP RS13035
gene id: 1379270:GEMMAAP_RS13035
uniprot id: A0A143BLJ0
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1379270:GEMMAAP RS10350
gene id: 1379270:GEMMAAP_RS10350
uniprot id: A0A143BJA7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1379270:GEMMAAP RS07380
gene id: 1379270:GEMMAAP_RS07380
uniprot id: A0A143BNK8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS08605
gene id: 1379270:GEMMAAP_RS08605
uniprot id: A0A143BIN2
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1379270:GEMMAAP RS08955
gene id: 1379270:GEMMAAP_RS08955
uniprot id: A0A143BQG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1379270:GEMMAAP RS06345
gene id: 1379270:GEMMAAP_RS06345
uniprot id: A0A143BIX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1379270:GEMMAAP RS15260
gene id: 1379270:GEMMAAP_RS15260
uniprot id: A0A143BL60
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1379270:GEMMAAP RS05170
gene id: 1379270:GEMMAAP_RS05170
uniprot id: A0A143BH60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1379270:GEMMAAP RS10090
gene id: 1379270:GEMMAAP_RS10090
uniprot id: A0A143BKF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1379270:GEMMAAP RS14615
gene id: 1379270:GEMMAAP_RS14615
uniprot id: A0A143BL13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS12830
gene id: 1379270:GEMMAAP_RS12830
uniprot id: A0A143BK70
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1379270:GEMMAAP RS03790
gene id: 1379270:GEMMAAP_RS03790
uniprot id: A0A143BI19
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1379270:GEMMAAP RS12025
gene id: 1379270:GEMMAAP_RS12025
uniprot id: A0A143BJR6
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1379270:GEMMAAP RS10125
gene id: 1379270:GEMMAAP_RS10125
uniprot id: A0A143BJ73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1379270:GEMMAAP RS07545
gene id: 1379270:GEMMAAP_RS07545
uniprot id: A0A143BI69
names: Similarity
messages: Belongs to the peptidase S9C family.

1379270:GEMMAAP RS05140
gene id: 1379270:GEMMAAP_RS05140
uniprot id: A0A143BIK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1379270:GEMMAAP RS15450
gene id: 1379270:GEMMAAP_RS15450
uniprot id: A0A143BLB3
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1379270:GEMMAAP RS08285
gene id: 1379270:GEMMAAP_RS08285
uniprot id: A0A143BIE8
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1379270:GEMMAAP RS14955
gene id: 1379270:GEMMAAP_RS14955
uniprot id: A0A143BMP9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1379270:GEMMAAP RS07355
gene id: 1379270:GEMMAAP_RS07355
uniprot id: A0A143BJE0
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS03200
gene id: 1379270:GEMMAAP_RS03200
uniprot id: A0A143BGE2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1379270:GEMMAAP RS14490
gene id: 1379270:GEMMAAP_RS14490
uniprot id: A0A143BKV9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS00710
gene id: 1379270:GEMMAAP_RS00710
uniprot id: A0A143BFG8
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1379270:GEMMAAP RS03490
gene id: 1379270:GEMMAAP_RS03490
uniprot id: A0A143BHY6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1379270:GEMMAAP RS06045
gene id: 1379270:GEMMAAP_RS06045
uniprot id: A0A143BIV2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1379270:GEMMAAP RS15640
gene id: 1379270:GEMMAAP_RS15640
uniprot id: A0A143BLE6
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS18550
gene id: 1379270:GEMMAAP_RS18550
uniprot id: A0A143BP42
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1379270:GEMMAAP RS04875
gene id: 1379270:GEMMAAP_RS04875
uniprot id: A0A143BH24
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

1379270:GEMMAAP RS14345
gene id: 1379270:GEMMAAP_RS14345
uniprot id: A0A143BMD4
names: Similarity
messages: Belongs to the universal stress protein A family.

1379270:GEMMAAP RS15470
gene id: 1379270:GEMMAAP_RS15470
uniprot id: A0A143BMR3
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1379270:GEMMAAP RS06460
gene id: 1379270:GEMMAAP_RS06460
uniprot id: A0A143BJE9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1379270:GEMMAAP RS16785
gene id: 1379270:GEMMAAP_RS16785
uniprot id: A0A143BNE5
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1379270:GEMMAAP RS14055
gene id: 1379270:GEMMAAP_RS14055
uniprot id: A0A143BKP7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1379270:GEMMAAP RS09640
gene id: 1379270:GEMMAAP_RS09640
uniprot id: A0A143BKD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1379270:GEMMAAP RS11390
gene id: 1379270:GEMMAAP_RS11390
uniprot id: A0A143BL27
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1379270:GEMMAAP RS17405
gene id: 1379270:GEMMAAP_RS17405
uniprot id: A0A143BM24
names: Similarity
messages: Belongs to the pirin family.

1379270:GEMMAAP RS15710
gene id: 1379270:GEMMAAP_RS15710
uniprot id: A0A143BMU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS07940
gene id: 1379270:GEMMAAP_RS07940
uniprot id: A0A143BIE0
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1379270:GEMMAAP RS04635
gene id: 1379270:GEMMAAP_RS04635
uniprot id: A0A143BGY3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1379270:GEMMAAP RS16965
gene id: 1379270:GEMMAAP_RS16965
uniprot id: A0A143BNE3
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS09005
gene id: 1379270:GEMMAAP_RS09005
uniprot id: A0A143BK59
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1379270:GEMMAAP RS12540
gene id: 1379270:GEMMAAP_RS12540
uniprot id: A0A143BLJ6
names: Similarity
messages: Belongs to the peptidase S13 family.

1379270:GEMMAAP RS08280
gene id: 1379270:GEMMAAP_RS08280
uniprot id: A0A143BJQ1
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1379270:GEMMAAP RS01675
gene id: 1379270:GEMMAAP_RS01675
uniprot id: A0A143BH07
names: Similarity
messages: Belongs to the UPF0434 family.

1379270:GEMMAAP RS19585
gene id: 1379270:GEMMAAP_RS19585
uniprot id: A0A143BPL6
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1379270:GEMMAAP RS15500
gene id: 1379270:GEMMAAP_RS15500
uniprot id: A0A143BLC1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1379270:GEMMAAP RS19535
gene id: 1379270:GEMMAAP_RS19535
uniprot id: A0A143BMT3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1379270:GEMMAAP RS00120
gene id: 1379270:GEMMAAP_RS00120
uniprot id: A0A143BGF2
names: Similarity
messages: Belongs to the peptidase U62 family.

1379270:GEMMAAP RS13270
gene id: 1379270:GEMMAAP_RS13270
uniprot id: A0A143BKF0
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS19470
gene id: 1379270:GEMMAAP_RS19470
uniprot id: A0A143BMQ1
names: Similarity
messages: Belongs to the peptidase S33 family.

1379270:GEMMAAP RS04585
gene id: 1379270:GEMMAAP_RS04585
uniprot id: A0A143BGX9
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1379270:GEMMAAP RS15035
gene id: 1379270:GEMMAAP_RS15035
uniprot id: A0A143BMB3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1379270:GEMMAAP RS01540
gene id: 1379270:GEMMAAP_RS01540
uniprot id: A0A143BHJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1379270:GEMMAAP RS07040
gene id: 1379270:GEMMAAP_RS07040
uniprot id: A0A143BJD8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1379270:GEMMAAP RS02990
gene id: 1379270:GEMMAAP_RS02990
uniprot id: A0A143BI30
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS09905
gene id: 1379270:GEMMAAP_RS09905
uniprot id: A0A143BJ54
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1379270:GEMMAAP RS15525
gene id: 1379270:GEMMAAP_RS15525
uniprot id: A0A143BMS3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1379270:GEMMAAP RS18710
gene id: 1379270:GEMMAAP_RS18710
uniprot id: A0A143BNX3
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

1379270:GEMMAAP RS11235
gene id: 1379270:GEMMAAP_RS11235
uniprot id: A0A143BKS2
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

1379270:GEMMAAP RS17570
gene id: 1379270:GEMMAAP_RS17570
uniprot id: A0A143BN93
names: Similarity
messages: Belongs to the RuBisCO large chain family.

1379270:GEMMAAP RS12045
gene id: 1379270:GEMMAAP_RS12045
uniprot id: A0A143BLC8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1379270:GEMMAAP RS10880
gene id: 1379270:GEMMAAP_RS10880
uniprot id: A0A143BKV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1379270:GEMMAAP RS16845
gene id: 1379270:GEMMAAP_RS16845
uniprot id: A0A143BN94
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1379270:GEMMAAP RS14970
gene id: 1379270:GEMMAAP_RS14970
uniprot id: A0A143BPG8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

1379270:GEMMAAP RS10185
gene id: 1379270:GEMMAAP_RS10185
uniprot id: A0A143BKQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1379270:GEMMAAP RS10570
gene id: 1379270:GEMMAAP_RS10570
uniprot id: A0A143BJ94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1379270:GEMMAAP RS13430
gene id: 1379270:GEMMAAP_RS13430
uniprot id: A0A143BM54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1379270:GEMMAAP RS05190
gene id: 1379270:GEMMAAP_RS05190
uniprot id: A0A143BII8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1379270:GEMMAAP RS13260
gene id: 1379270:GEMMAAP_RS13260
uniprot id: A0A143BKA8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1379270:GEMMAAP RS08300
gene id: 1379270:GEMMAAP_RS08300
uniprot id: A0A143BIG6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1379270:GEMMAAP RS05895
gene id: 1379270:GEMMAAP_RS05895
uniprot id: A0A143BJ43
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS09675
gene id: 1379270:GEMMAAP_RS09675
uniprot id: A0A143BJ27
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1379270:GEMMAAP RS06980
gene id: 1379270:GEMMAAP_RS06980
uniprot id: A0A143BJL6
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1379270:GEMMAAP RS15480
gene id: 1379270:GEMMAAP_RS15480
uniprot id: A0A143BMZ3
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

1379270:GEMMAAP RS10270
gene id: 1379270:GEMMAAP_RS10270
uniprot id: A0A143BJ96
names: Similarity
messages: Belongs to the group II decarboxylase family.

1379270:GEMMAAP RS08975
gene id: 1379270:GEMMAAP_RS08975
uniprot id: A0A143BIS9
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1379270:GEMMAAP RS08825
gene id: 1379270:GEMMAAP_RS08825
uniprot id: A0A143BJX5
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1379270:GEMMAAP RS13755
gene id: 1379270:GEMMAAP_RS13755
uniprot id: A0A143BKK9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1379270:GEMMAAP RS12435
gene id: 1379270:GEMMAAP_RS12435
uniprot id: A0A143BLN9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1379270:GEMMAAP RS04900
gene id: 1379270:GEMMAAP_RS04900
uniprot id: A0A143BIQ1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1379270:GEMMAAP RS07420
gene id: 1379270:GEMMAAP_RS07420
uniprot id: A0A143BJF1
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1379270:GEMMAAP RS12595
gene id: 1379270:GEMMAAP_RS12595
uniprot id: A0A143BLK0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1379270:GEMMAAP RS02520
gene id: 1379270:GEMMAAP_RS02520
uniprot id: A0A143BG57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1379270:GEMMAAP RS01680
gene id: 1379270:GEMMAAP_RS01680
uniprot id: A0A143BHA9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1379270:GEMMAAP RS09815
gene id: 1379270:GEMMAAP_RS09815
uniprot id: A0A143BJ47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1379270:GEMMAAP RS19385
gene id: 1379270:GEMMAAP_RS19385
uniprot id: A0A143BP05
names: Similarity
messages: Belongs to the VgrG protein family.

1379270:GEMMAAP RS10195
gene id: 1379270:GEMMAAP_RS10195
uniprot id: A0A143BKM3
names: Similarity
messages: Belongs to the Pal lipoprotein family.

1379270:GEMMAAP RS15335
gene id: 1379270:GEMMAAP_RS15335
uniprot id: A0A145Q517
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1379270:GEMMAAP RS12355
gene id: 1379270:GEMMAAP_RS12355
uniprot id: A0A143BP21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1379270:GEMMAAP RS09035
gene id: 1379270:GEMMAAP_RS09035
uniprot id: A0A143BIP5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1379270:GEMMAAP RS13505
gene id: 1379270:GEMMAAP_RS13505
uniprot id: A0A143BM62
names: Similarity
messages: Belongs to the peptidase M16 family.

1379270:GEMMAAP RS04890
gene id: 1379270:GEMMAAP_RS04890
uniprot id: A0A143BH28
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1379270:GEMMAAP RS06685
gene id: 1379270:GEMMAAP_RS06685
uniprot id: A0A143BJ26
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS11870
gene id: 1379270:GEMMAAP_RS11870
uniprot id: A0A143BL23
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1379270:GEMMAAP RS08510
gene id: 1379270:GEMMAAP_RS08510
uniprot id: A0A143BK94
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1379270:GEMMAAP RS09305
gene id: 1379270:GEMMAAP_RS09305
uniprot id: A0A143BIX6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1379270:GEMMAAP RS17625
gene id: 1379270:GEMMAAP_RS17625
uniprot id: A0A143BNK2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1379270:GEMMAAP RS10075
gene id: 1379270:GEMMAAP_RS10075
uniprot id: A0A143BKL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1379270:GEMMAAP RS07405
gene id: 1379270:GEMMAAP_RS07405
uniprot id: A0A143BJL2
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1379270:GEMMAAP RS03895
gene id: 1379270:GEMMAAP_RS03895
uniprot id: A0A143BIB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1379270:GEMMAAP RS06620
gene id: 1379270:GEMMAAP_RS06620
uniprot id: A0A143BJ63
names: Similarity
messages: Belongs to the NifH/BchL/ChlL family.

1379270:GEMMAAP RS08945
gene id: 1379270:GEMMAAP_RS08945
uniprot id: A0A143BJZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1379270:GEMMAAP RS14575
gene id: 1379270:GEMMAAP_RS14575
uniprot id: A0A143BMF2
names: Similarity
messages: Belongs to the universal stress protein A family.

1379270:GEMMAAP RS18005
gene id: 1379270:GEMMAAP_RS18005
uniprot id: A0A143BNY6
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS04895
gene id: 1379270:GEMMAAP_RS04895
uniprot id: A0A143BH43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1379270:GEMMAAP RS12490
gene id: 1379270:GEMMAAP_RS12490
uniprot id: A0A143BLB1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1379270:GEMMAAP RS03715
gene id: 1379270:GEMMAAP_RS03715
uniprot id: A0A143BN67
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1379270:GEMMAAP RS03220
gene id: 1379270:GEMMAAP_RS03220
uniprot id: A0A143BGD4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1379270:GEMMAAP RS03720
gene id: 1379270:GEMMAAP_RS03720
uniprot id: A0A143BGI8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1379270:GEMMAAP RS12030
gene id: 1379270:GEMMAAP_RS12030
uniprot id: A0A143BJR7
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS11960
gene id: 1379270:GEMMAAP_RS11960
uniprot id: A0A143BJQ6
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1379270:GEMMAAP RS09025
gene id: 1379270:GEMMAAP_RS09025
uniprot id: A0A143BKH4
names: Similarity
messages: Belongs to the NDK family.

1379270:GEMMAAP RS03955
gene id: 1379270:GEMMAAP_RS03955
uniprot id: A0A143BGP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1379270:GEMMAAP RS01105
gene id: 1379270:GEMMAAP_RS01105
uniprot id: A0A143BH35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1379270:GEMMAAP RS02010
gene id: 1379270:GEMMAAP_RS02010
uniprot id: A0A143BH55
names: Similarity
messages: Belongs to the CIA30 family.

1379270:GEMMAAP RS10175
gene id: 1379270:GEMMAAP_RS10175
uniprot id: A0A143BJ88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

1379270:GEMMAAP RS14700
gene id: 1379270:GEMMAAP_RS14700
uniprot id: A0A143BL25
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1379270:GEMMAAP RS11650
gene id: 1379270:GEMMAAP_RS11650
uniprot id: A0A143BKZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1379270:GEMMAAP RS17720
gene id: 1379270:GEMMAAP_RS17720
uniprot id: A0A143BNV2
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1379270:GEMMAAP RS09685
gene id: 1379270:GEMMAAP_RS09685
uniprot id: A0A143BKI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1379270:GEMMAAP RS18665
gene id: 1379270:GEMMAAP_RS18665
uniprot id: A0A143BMD7
names: Similarity
messages: Belongs to the RutC family.

1379270:GEMMAAP RS10595
gene id: 1379270:GEMMAAP_RS10595
uniprot id: A0A143BJD3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1379270:GEMMAAP RS05250
gene id: 1379270:GEMMAAP_RS05250
uniprot id: A0A143BNH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1379270:GEMMAAP RS20315
gene id: 1379270:GEMMAAP_RS20315
uniprot id: A0A143BLR1
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS07210
gene id: 1379270:GEMMAAP_RS07210
uniprot id: A0A143BI08
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS13445
gene id: 1379270:GEMMAAP_RS13445
uniprot id: A0A143BKD6
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1379270:GEMMAAP RS16380
gene id: 1379270:GEMMAAP_RS16380
uniprot id: A0A143BN34
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1379270:GEMMAAP RS04505
gene id: 1379270:GEMMAAP_RS04505
uniprot id: A0A143BI35
names: Similarity
messages: Belongs to the NodU/CmcH family.

1379270:GEMMAAP RS08090
gene id: 1379270:GEMMAAP_RS08090
uniprot id: A0A143BIF9
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS14510
gene id: 1379270:GEMMAAP_RS14510
uniprot id: A0A143BMH7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1379270:GEMMAAP RS04525
gene id: 1379270:GEMMAAP_RS04525
uniprot id: A0A143BGV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1379270:GEMMAAP RS19885
gene id: 1379270:GEMMAAP_RS19885
uniprot id: A0A143BPD4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1379270:GEMMAAP RS01045
gene id: 1379270:GEMMAAP_RS01045
uniprot id: A0A143BH26
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS11545
gene id: 1379270:GEMMAAP_RS11545
uniprot id: A0A143BLB9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1379270:GEMMAAP RS05855
gene id: 1379270:GEMMAAP_RS05855
uniprot id: A0A143BIQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1379270:GEMMAAP RS16100
gene id: 1379270:GEMMAAP_RS16100
uniprot id: A0A143BN14
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1379270:GEMMAAP RS19865
gene id: 1379270:GEMMAAP_RS19865
uniprot id: A0A143BPI1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS18265
gene id: 1379270:GEMMAAP_RS18265
uniprot id: A0A143BP07
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1379270:GEMMAAP RS00980
gene id: 1379270:GEMMAAP_RS00980
uniprot id: A0A143BH15
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1379270:GEMMAAP RS05175
gene id: 1379270:GEMMAAP_RS05175
uniprot id: A0A143BH76
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1379270:GEMMAAP RS00975
gene id: 1379270:GEMMAAP_RS00975
uniprot id: A0A143BGQ1
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS04205
gene id: 1379270:GEMMAAP_RS04205
uniprot id: A0A143BGS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1379270:GEMMAAP RS10345
gene id: 1379270:GEMMAAP_RS10345
uniprot id: A0A143BJ71
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS08860
gene id: 1379270:GEMMAAP_RS08860
uniprot id: A0A143BK62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1379270:GEMMAAP RS08680
gene id: 1379270:GEMMAAP_RS08680
uniprot id: A0A143BKB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1379270:GEMMAAP RS16195
gene id: 1379270:GEMMAAP_RS16195
uniprot id: A0A143BN96
names: Similarity
messages: Belongs to the TrpF family.

1379270:GEMMAAP RS09065
gene id: 1379270:GEMMAAP_RS09065
uniprot id: A0A143BIT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1379270:GEMMAAP RS03175
gene id: 1379270:GEMMAAP_RS03175
uniprot id: A0A143BHU8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1379270:GEMMAAP RS02760
gene id: 1379270:GEMMAAP_RS02760
uniprot id: A0A143BHP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1379270:GEMMAAP RS04730
gene id: 1379270:GEMMAAP_RS04730
uniprot id: A0A143BIA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1379270:GEMMAAP RS11845
gene id: 1379270:GEMMAAP_RS11845
uniprot id: A0A143BL87
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1379270:GEMMAAP RS05150
gene id: 1379270:GEMMAAP_RS05150
uniprot id: A0A143BIX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1379270:GEMMAAP RS10960
gene id: 1379270:GEMMAAP_RS10960
uniprot id: A0A143BJH7
names: Similarity
messages: Belongs to the UPF0502 family.

1379270:GEMMAAP RS14670
gene id: 1379270:GEMMAAP_RS14670
uniprot id: A0A143BMN5
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1379270:GEMMAAP RS06350
gene id: 1379270:GEMMAAP_RS06350
uniprot id: A0A143BHN2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1379270:GEMMAAP RS11040
gene id: 1379270:GEMMAAP_RS11040
uniprot id: A0A143BL04
names: Caution
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1379270:GEMMAAP RS12405
gene id: 1379270:GEMMAAP_RS12405
uniprot id: A0A143BK12
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1379270:GEMMAAP RS10210
gene id: 1379270:GEMMAAP_RS10210
uniprot id: A0A143BKX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1379270:GEMMAAP RS14205
gene id: 1379270:GEMMAAP_RS14205
uniprot id: A0A145Q4L7
names: Similarity
messages: Belongs to the universal stress protein A family.

1379270:GEMMAAP RS10375
gene id: 1379270:GEMMAAP_RS10375
uniprot id: A0A143BKQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1379270:GEMMAAP RS06600
gene id: 1379270:GEMMAAP_RS06600
uniprot id: A0A143BHS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
messages: Belongs to the antenna complex beta subunit family.
messages: Membrane

1379270:GEMMAAP RS08505
gene id: 1379270:GEMMAAP_RS08505
uniprot id: A0A143BJS4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1379270:GEMMAAP RS03160
gene id: 1379270:GEMMAAP_RS03160
uniprot id: A0A143BGC4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1379270:GEMMAAP RS06675
gene id: 1379270:GEMMAAP_RS06675
uniprot id: A0A143BJ48
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS02385
gene id: 1379270:GEMMAAP_RS02385
uniprot id: A0A143BG42
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1379270:GEMMAAP RS15275
gene id: 1379270:GEMMAAP_RS15275
uniprot id: A0A143BL95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1379270:GEMMAAP RS02345
gene id: 1379270:GEMMAAP_RS02345
uniprot id: A0A143BHP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

1379270:GEMMAAP RS09610
gene id: 1379270:GEMMAAP_RS09610
uniprot id: A0A143BJ15
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1379270:GEMMAAP RS18730
gene id: 1379270:GEMMAAP_RS18730
uniprot id: A0A143BNT9
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS05850
gene id: 1379270:GEMMAAP_RS05850
uniprot id: A0A143BIV6
names: Similarity
messages: Belongs to the SusD family.

1379270:GEMMAAP RS12340
gene id: 1379270:GEMMAAP_RS12340
uniprot id: A0A143BLH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1379270:GEMMAAP RS01700
gene id: 1379270:GEMMAAP_RS01700
uniprot id: A0A143BFW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1379270:GEMMAAP RS10750
gene id: 1379270:GEMMAAP_RS10750
uniprot id: A0A143BKU7
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

1379270:GEMMAAP RS08020
gene id: 1379270:GEMMAAP_RS08020
uniprot id: A0A143BIE9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1379270:GEMMAAP RS16135
gene id: 1379270:GEMMAAP_RS16135
uniprot id: A0A143BLI1
names: Similarity
messages: Belongs to the DinB family.

1379270:GEMMAAP RS12360
gene id: 1379270:GEMMAAP_RS12360
uniprot id: A0A143BL77
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1379270:GEMMAAP RS03170
gene id: 1379270:GEMMAAP_RS03170
uniprot id: A0A143BHM1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1379270:GEMMAAP RS13025
gene id: 1379270:GEMMAAP_RS13025
uniprot id: A0A143BLH9
names: Similarity
messages: Belongs to the DSD1 family.

1379270:GEMMAAP RS05065
gene id: 1379270:GEMMAAP_RS05065
uniprot id: A0A143BIG3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1379270:GEMMAAP RS03740
gene id: 1379270:GEMMAAP_RS03740
uniprot id: A0A143BI12
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1379270:GEMMAAP RS14160
gene id: 1379270:GEMMAAP_RS14160
uniprot id: A0A143BM23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1379270:GEMMAAP RS09655
gene id: 1379270:GEMMAAP_RS09655
uniprot id: A0A143BKP3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1379270:GEMMAAP RS18820
gene id: 1379270:GEMMAAP_RS18820
uniprot id: A0A143BMI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1379270:GEMMAAP RS08585
gene id: 1379270:GEMMAAP_RS08585
uniprot id: A0A143BJU5
names: Similarity
messages: Belongs to the RutC family.

1379270:GEMMAAP RS05800
gene id: 1379270:GEMMAAP_RS05800
uniprot id: A0A143BJ64
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS08565
gene id: 1379270:GEMMAAP_RS08565
uniprot id: A0A143BJT3
names: Similarity
messages: Belongs to the ribF family.

1379270:GEMMAAP RS04905
gene id: 1379270:GEMMAAP_RS04905
uniprot id: A0A143BNC1
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1379270:GEMMAAP RS09230
gene id: 1379270:GEMMAAP_RS09230
uniprot id: A0A143BIW5
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1379270:GEMMAAP RS08380
gene id: 1379270:GEMMAAP_RS08380
uniprot id: A0A143BK14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1379270:GEMMAAP RS17475
gene id: 1379270:GEMMAAP_RS17475
uniprot id: A0A143BNK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1379270:GEMMAAP RS08990
gene id: 1379270:GEMMAAP_RS08990
uniprot id: A0A143BKA3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1379270:GEMMAAP RS04665
gene id: 1379270:GEMMAAP_RS04665
uniprot id: A0A143BI97
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1379270:GEMMAAP RS02895
gene id: 1379270:GEMMAAP_RS02895
uniprot id: A0A143BHR3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1379270:GEMMAAP RS17200
gene id: 1379270:GEMMAAP_RS17200
uniprot id: A0A143BNK3
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1379270:GEMMAAP RS03090
gene id: 1379270:GEMMAAP_RS03090
uniprot id: A0A143BGC1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS09845
gene id: 1379270:GEMMAAP_RS09845
uniprot id: A0A143BKA0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1379270:GEMMAAP RS07890
gene id: 1379270:GEMMAAP_RS07890
uniprot id: A0A143BJK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1379270:GEMMAAP RS04610
gene id: 1379270:GEMMAAP_RS04610
uniprot id: A0A143BID1
names: Similarity
messages: Belongs to the peptidase M16 family.

1379270:GEMMAAP RS07285
gene id: 1379270:GEMMAAP_RS07285
uniprot id: A0A143BJD0
names: Similarity
messages: Belongs to the Dps family.

1379270:GEMMAAP RS10540
gene id: 1379270:GEMMAAP_RS10540
uniprot id: A0A143BKS6
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS10255
gene id: 1379270:GEMMAAP_RS10255
uniprot id: A0A143BJ61
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1379270:GEMMAAP RS08355
gene id: 1379270:GEMMAAP_RS08355
uniprot id: A0A143BNS0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1379270:GEMMAAP RS17210
gene id: 1379270:GEMMAAP_RS17210
uniprot id: A0A143BN41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1379270:GEMMAAP RS05355
gene id: 1379270:GEMMAAP_RS05355
uniprot id: A0A143BHA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1379270:GEMMAAP RS18980
gene id: 1379270:GEMMAAP_RS18980
uniprot id: A0A143BPA6
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS06730
gene id: 1379270:GEMMAAP_RS06730
uniprot id: A0A143BHU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1379270:GEMMAAP RS08360
gene id: 1379270:GEMMAAP_RS08360
uniprot id: A0A143BIF4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1379270:GEMMAAP RS15100
gene id: 1379270:GEMMAAP_RS15100
uniprot id: A0A143BMU4
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1379270:GEMMAAP RS10315
gene id: 1379270:GEMMAAP_RS10315
uniprot id: A0A143BKX8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1379270:GEMMAAP RS09645
gene id: 1379270:GEMMAAP_RS09645
uniprot id: A0A143BKG0
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS06410
gene id: 1379270:GEMMAAP_RS06410
uniprot id: A0A143BHP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS14210
gene id: 1379270:GEMMAAP_RS14210
uniprot id: A0A143BM87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

1379270:GEMMAAP RS06665
gene id: 1379270:GEMMAAP_RS06665
uniprot id: A0A143BHU2
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS10365
gene id: 1379270:GEMMAAP_RS10365
uniprot id: A0A143BKS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1379270:GEMMAAP RS11580
gene id: 1379270:GEMMAAP_RS11580
uniprot id: A0A143BJL0
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1379270:GEMMAAP RS06815
gene id: 1379270:GEMMAAP_RS06815
uniprot id: A0A143BJF3
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

1379270:GEMMAAP RS12185
gene id: 1379270:GEMMAAP_RS12185
uniprot id: A0A143BJY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1379270:GEMMAAP RS16600
gene id: 1379270:GEMMAAP_RS16600
uniprot id: A0A143BLM4
names: Similarity
messages: Belongs to the peptidase M24B family.

1379270:GEMMAAP RS15495
gene id: 1379270:GEMMAAP_RS15495
uniprot id: A0A143BL94
names: Subunit
messages: Homodimer.

1379270:GEMMAAP RS07875
gene id: 1379270:GEMMAAP_RS07875
uniprot id: A0A143BJI9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS03830
gene id: 1379270:GEMMAAP_RS03830
uniprot id: A0A143BIA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1379270:GEMMAAP RS08780
gene id: 1379270:GEMMAAP_RS08780
uniprot id: A0A143BIQ0
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1379270:GEMMAAP RS05070
gene id: 1379270:GEMMAAP_RS05070
uniprot id: A0A143BIK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1379270:GEMMAAP RS01820
gene id: 1379270:GEMMAAP_RS01820
uniprot id: A0A143BH17
names: Similarity
messages: Belongs to the asparaginase 1 family.

1379270:GEMMAAP RS04645
gene id: 1379270:GEMMAAP_RS04645
uniprot id: A0A143BGY9
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1379270:GEMMAAP RS10525
gene id: 1379270:GEMMAAP_RS10525
uniprot id: A0A143BJC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1379270:GEMMAAP RS06785
gene id: 1379270:GEMMAAP_RS06785
uniprot id: A0A143BNI8
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1379270:GEMMAAP RS14625
gene id: 1379270:GEMMAAP_RS14625
uniprot id: A0A143BMH2
names: Similarity
messages: Belongs to the DEAD box helicase family.

1379270:GEMMAAP RS07860
gene id: 1379270:GEMMAAP_RS07860
uniprot id: A0A143BJU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1379270:GEMMAAP RS06320
gene id: 1379270:GEMMAAP_RS06320
uniprot id: A0A143BJ22
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS18615
gene id: 1379270:GEMMAAP_RS18615
uniprot id: A0A143BR27
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

1379270:GEMMAAP RS09985
gene id: 1379270:GEMMAAP_RS09985
uniprot id: A0A143BJ55
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1379270:GEMMAAP RS14330
gene id: 1379270:GEMMAAP_RS14330
uniprot id: A0A143BKQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1379270:GEMMAAP RS08110
gene id: 1379270:GEMMAAP_RS08110
uniprot id: A0A143BJU8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1379270:GEMMAAP RS19530
gene id: 1379270:GEMMAAP_RS19530
uniprot id: A0A143BMR6
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS01630
gene id: 1379270:GEMMAAP_RS01630
uniprot id: A0A143BFU4
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1379270:GEMMAAP RS04740
gene id: 1379270:GEMMAAP_RS04740
uniprot id: A0A143BI76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1379270:GEMMAAP RS05205
gene id: 1379270:GEMMAAP_RS05205
uniprot id: A0A143BIE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1379270:GEMMAAP RS20680
gene id: 1379270:GEMMAAP_RS20680
uniprot id: A0A143BLZ8
names: Similarity
messages: Belongs to the CIA30 family.

1379270:GEMMAAP RS00200
gene id: 1379270:GEMMAAP_RS00200
uniprot id: A0A143BFA1
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS06030
gene id: 1379270:GEMMAAP_RS06030
uniprot id: A0A143BHJ4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1379270:GEMMAAP RS02000
gene id: 1379270:GEMMAAP_RS02000
uniprot id: A0A143BFZ3
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1379270:GEMMAAP RS09090
gene id: 1379270:GEMMAAP_RS09090
uniprot id: A0A143BK92
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1379270:GEMMAAP RS05010
gene id: 1379270:GEMMAAP_RS05010
uniprot id: A0A143BH44
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1379270:GEMMAAP RS10500
gene id: 1379270:GEMMAAP_RS10500
uniprot id: A0A143BJC4
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1379270:GEMMAAP RS04970
gene id: 1379270:GEMMAAP_RS04970
uniprot id: A0A143BIR1
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1379270:GEMMAAP RS17500
gene id: 1379270:GEMMAAP_RS17500
uniprot id: A0A143BN80
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS10355
gene id: 1379270:GEMMAAP_RS10355
uniprot id: A0A143BJA5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1379270:GEMMAAP RS13535
gene id: 1379270:GEMMAAP_RS13535
uniprot id: A0A143BM02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1379270:GEMMAAP RS17575
gene id: 1379270:GEMMAAP_RS17575
uniprot id: A0A143BNT1
names: Similarity
messages: Belongs to the UPF0047 family.

1379270:GEMMAAP RS03910
gene id: 1379270:GEMMAAP_RS03910
uniprot id: A0A143BHW5
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS05210
gene id: 1379270:GEMMAAP_RS05210
uniprot id: A0A143BQ12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1379270:GEMMAAP RS04640
gene id: 1379270:GEMMAAP_RS04640
uniprot id: A0A143BGX7
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1379270:GEMMAAP RS01910
gene id: 1379270:GEMMAAP_RS01910
uniprot id: A0A143BFZ4
names: Similarity
messages: Belongs to the UPF0145 family.

1379270:GEMMAAP RS07275
gene id: 1379270:GEMMAAP_RS07275
uniprot id: A0A143BJS6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1379270:GEMMAAP RS11980
gene id: 1379270:GEMMAAP_RS11980
uniprot id: A0A143BLB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1379270:GEMMAAP RS07350
gene id: 1379270:GEMMAAP_RS07350
uniprot id: A0A143BJT8
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1379270:GEMMAAP RS13310
gene id: 1379270:GEMMAAP_RS13310
uniprot id: A0A143BM35
names: Similarity
messages: Belongs to the GSP E family.

1379270:GEMMAAP RS12590
gene id: 1379270:GEMMAAP_RS12590
uniprot id: A0A143BLL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1379270:GEMMAAP RS09625
gene id: 1379270:GEMMAAP_RS09625
uniprot id: A0A143BJ07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1379270:GEMMAAP RS12290
gene id: 1379270:GEMMAAP_RS12290
uniprot id: A0A143BLE9
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1379270:GEMMAAP RS04925
gene id: 1379270:GEMMAAP_RS04925
uniprot id: A0A143BIH0
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1379270:GEMMAAP RS16865
gene id: 1379270:GEMMAAP_RS16865
uniprot id: A0A143BN35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1379270:GEMMAAP RS17305
gene id: 1379270:GEMMAAP_RS17305
uniprot id: A0A143BN90
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1379270:GEMMAAP RS14540
gene id: 1379270:GEMMAAP_RS14540
uniprot id: A0A143BKW2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1379270:GEMMAAP RS08885
gene id: 1379270:GEMMAAP_RS08885
uniprot id: A0A143BJY6
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS09010
gene id: 1379270:GEMMAAP_RS09010
uniprot id: A0A143BK82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1379270:GEMMAAP RS04860
gene id: 1379270:GEMMAAP_RS04860
uniprot id: A0A143BI98
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1379270:GEMMAAP RS04990
gene id: 1379270:GEMMAAP_RS04990
uniprot id: A0A143BIB7
names: Similarity
messages: Belongs to the PspA/IM30 family.

1379270:GEMMAAP RS04085
gene id: 1379270:GEMMAAP_RS04085
uniprot id: A0A143BGQ8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1379270:GEMMAAP RS00320
gene id: 1379270:GEMMAAP_RS00320
uniprot id: A0A143BFC1
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS10715
gene id: 1379270:GEMMAAP_RS10715
uniprot id: A0A143BJB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1379270:GEMMAAP RS19850
gene id: 1379270:GEMMAAP_RS19850
uniprot id: A0A143BMX2
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1379270:GEMMAAP RS19220
gene id: 1379270:GEMMAAP_RS19220
uniprot id: A0A143BP06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1379270:GEMMAAP RS08385
gene id: 1379270:GEMMAAP_RS08385
uniprot id: A0A143BJX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1379270:GEMMAAP RS04050
gene id: 1379270:GEMMAAP_RS04050
uniprot id: A0A143BHZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1379270:GEMMAAP RS07310
gene id: 1379270:GEMMAAP_RS07310
uniprot id: A0A143BI55
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1379270:GEMMAAP RS06530
gene id: 1379270:GEMMAAP_RS06530
uniprot id: A0A143BJC1
names: Similarity
messages: Belongs to the PucC family.

1379270:GEMMAAP RS02300
gene id: 1379270:GEMMAAP_RS02300
uniprot id: A0A143BHU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

1379270:GEMMAAP RS13335
gene id: 1379270:GEMMAAP_RS13335
uniprot id: A0A143BKG1
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS06970
gene id: 1379270:GEMMAAP_RS06970
uniprot id: A0A143BJ68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1379270:GEMMAAP RS10700
gene id: 1379270:GEMMAAP_RS10700
uniprot id: A0A143BL28
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1379270:GEMMAAP RS15965
gene id: 1379270:GEMMAAP_RS15965
uniprot id: A0A143BLI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1379270:GEMMAAP RS09945
gene id: 1379270:GEMMAAP_RS09945
uniprot id: A0A143BKB1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1379270:GEMMAAP RS15360
gene id: 1379270:GEMMAAP_RS15360
uniprot id: A0A143BL75
names: Similarity
messages: Belongs to the peptidase S9C family.

1379270:GEMMAAP RS12545
gene id: 1379270:GEMMAAP_RS12545
uniprot id: A0A143BLB5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1379270:GEMMAAP RS12280
gene id: 1379270:GEMMAAP_RS12280
uniprot id: A0A143BLG6
names: Similarity
messages: Belongs to the cytochrome P450 family.

1379270:GEMMAAP RS08555
gene id: 1379270:GEMMAAP_RS08555
uniprot id: A0A143BK01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1379270:GEMMAAP RS13545
gene id: 1379270:GEMMAAP_RS13545
uniprot id: A0A143BLZ9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1379270:GEMMAAP RS01135
gene id: 1379270:GEMMAAP_RS01135
uniprot id: A0A143BFN7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1379270:GEMMAAP RS04595
gene id: 1379270:GEMMAAP_RS04595
uniprot id: A0A143BGZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1379270:GEMMAAP RS04820
gene id: 1379270:GEMMAAP_RS04820
uniprot id: A0A143BH09
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1379270:GEMMAAP RS05055
gene id: 1379270:GEMMAAP_RS05055
uniprot id: A0A143BIS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1379270:GEMMAAP RS10070
gene id: 1379270:GEMMAAP_RS10070
uniprot id: A0A143BKJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1379270:GEMMAAP RS15065
gene id: 1379270:GEMMAAP_RS15065
uniprot id: A0A143BL29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1379270:GEMMAAP RS12155
gene id: 1379270:GEMMAAP_RS12155
uniprot id: A0A143BL63
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1379270:GEMMAAP RS00995
gene id: 1379270:GEMMAAP_RS00995
uniprot id: A0A143BGQ5
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1379270:GEMMAAP RS13140
gene id: 1379270:GEMMAAP_RS13140
uniprot id: A0A143BLU0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1379270:GEMMAAP RS18825
gene id: 1379270:GEMMAAP_RS18825
uniprot id: A0A143BMM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1379270:GEMMAAP RS08030
gene id: 1379270:GEMMAAP_RS08030
uniprot id: A0A143BIC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1379270:GEMMAAP RS11065
gene id: 1379270:GEMMAAP_RS11065
uniprot id: A0A143BL74
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS07655
gene id: 1379270:GEMMAAP_RS07655
uniprot id: A0A143BI60
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1379270:GEMMAAP RS06790
gene id: 1379270:GEMMAAP_RS06790
uniprot id: A0A143BJ46
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1379270:GEMMAAP RS07410
gene id: 1379270:GEMMAAP_RS07410
uniprot id: A0A143BJD7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1379270:GEMMAAP RS04540
gene id: 1379270:GEMMAAP_RS04540
uniprot id: A0A143BIJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1379270:GEMMAAP RS09115
gene id: 1379270:GEMMAAP_RS09115
uniprot id: A0A143BK02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1379270:GEMMAAP RS11175
gene id: 1379270:GEMMAAP_RS11175
uniprot id: A0A143BJG3
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

1379270:GEMMAAP RS13425
gene id: 1379270:GEMMAAP_RS13425
uniprot id: A0A143BLN6
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1379270:GEMMAAP RS12270
gene id: 1379270:GEMMAAP_RS12270
uniprot id: A0A143BJZ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1379270:GEMMAAP RS19180
gene id: 1379270:GEMMAAP_RS19180
uniprot id: A0A143BMM8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1379270:GEMMAAP RS18260
gene id: 1379270:GEMMAAP_RS18260
uniprot id: A0A143BNV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1379270:GEMMAAP RS14025
gene id: 1379270:GEMMAAP_RS14025
uniprot id: A0A143BKK5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1379270:GEMMAAP RS06655
gene id: 1379270:GEMMAAP_RS06655
uniprot id: A0A143BHS4
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS12850
gene id: 1379270:GEMMAAP_RS12850
uniprot id: A0A143BLF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1379270:GEMMAAP RS13870
gene id: 1379270:GEMMAAP_RS13870
uniprot id: A0A145Q4J0
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

1379270:GEMMAAP RS05165
gene id: 1379270:GEMMAAP_RS05165
uniprot id: A0A143BH59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1379270:GEMMAAP RS19740
gene id: 1379270:GEMMAAP_RS19740
uniprot id: A0A143BN05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intimin/invasin family.
messages: Cell outer membrane
messages: Membrane

1379270:GEMMAAP RS10730
gene id: 1379270:GEMMAAP_RS10730
uniprot id: A0A143BJF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1379270:GEMMAAP RS15775
gene id: 1379270:GEMMAAP_RS15775
uniprot id: A0A143BMV1
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

1379270:GEMMAAP RS16495
gene id: 1379270:GEMMAAP_RS16495
uniprot id: A0A143BLM8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS03880
gene id: 1379270:GEMMAAP_RS03880
uniprot id: A0A143BGM4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS15530
gene id: 1379270:GEMMAAP_RS15530
uniprot id: A0A143BMH5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1379270:GEMMAAP RS14350
gene id: 1379270:GEMMAAP_RS14350
uniprot id: A0A143BME5
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS09440
gene id: 1379270:GEMMAAP_RS09440
uniprot id: A0A143BK66
names: Similarity
messages: Belongs to the TrpF family.

1379270:GEMMAAP RS07455
gene id: 1379270:GEMMAAP_RS07455
uniprot id: A0A143BI29
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1379270:GEMMAAP RS18685
gene id: 1379270:GEMMAAP_RS18685
uniprot id: A0A143BMK6
names: Similarity
messages: Belongs to the cytochrome b562 family.

1379270:GEMMAAP RS07230
gene id: 1379270:GEMMAAP_RS07230
uniprot id: A0A143BQ58
names: Similarity
messages: Belongs to the thioredoxin family.

1379270:GEMMAAP RS06840
gene id: 1379270:GEMMAAP_RS06840
uniprot id: A0A143BJ45
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1379270:GEMMAAP RS16205
gene id: 1379270:GEMMAAP_RS16205
uniprot id: A0A143BLJ1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1379270:GEMMAAP RS04735
gene id: 1379270:GEMMAAP_RS04735
uniprot id: A0A143BIE7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1379270:GEMMAAP RS16830
gene id: 1379270:GEMMAAP_RS16830
uniprot id: A0A143BLQ5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1379270:GEMMAAP RS06960
gene id: 1379270:GEMMAAP_RS06960
uniprot id: A0A143BJ83
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1379270:GEMMAAP RS13115
gene id: 1379270:GEMMAAP_RS13115
uniprot id: A0A143BKC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1379270:GEMMAAP RS03970
gene id: 1379270:GEMMAAP_RS03970
uniprot id: A0A143BI45
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS04040
gene id: 1379270:GEMMAAP_RS04040
uniprot id: A0A143BGQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1379270:GEMMAAP RS00075
gene id: 1379270:GEMMAAP_RS00075
uniprot id: A0A143BGD7
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS09395
gene id: 1379270:GEMMAAP_RS09395
uniprot id: A0A143BIY6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS17050
gene id: 1379270:GEMMAAP_RS17050
uniprot id: A0A143BLT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1379270:GEMMAAP RS00445
gene id: 1379270:GEMMAAP_RS00445
uniprot id: A0A143BFD9
names: Similarity
messages: Belongs to the HepT RNase toxin family.

1379270:GEMMAAP RS12040
gene id: 1379270:GEMMAAP_RS12040
uniprot id: A0A143BJW1
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS09565
gene id: 1379270:GEMMAAP_RS09565
uniprot id: A0A143BKF1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1379270:GEMMAAP RS08525
gene id: 1379270:GEMMAAP_RS08525
uniprot id: A0A143BII4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS07865
gene id: 1379270:GEMMAAP_RS07865
uniprot id: A0A143BJP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1379270:GEMMAAP RS09375
gene id: 1379270:GEMMAAP_RS09375
uniprot id: A0A143BIU4
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS02220
gene id: 1379270:GEMMAAP_RS02220
uniprot id: A0A143BHH8
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1379270:GEMMAAP RS12825
gene id: 1379270:GEMMAAP_RS12825
uniprot id: A0A143BK74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1379270:GEMMAAP RS02295
gene id: 1379270:GEMMAAP_RS02295
uniprot id: A0A143BHA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.

1379270:GEMMAAP RS13830
gene id: 1379270:GEMMAAP_RS13830
uniprot id: A0A143BLU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1379270:GEMMAAP RS12860
gene id: 1379270:GEMMAAP_RS12860
uniprot id: A0A143BLG4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1379270:GEMMAAP RS18285
gene id: 1379270:GEMMAAP_RS18285
uniprot id: A0A143BP25
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1379270:GEMMAAP RS09155
gene id: 1379270:GEMMAAP_RS09155
uniprot id: A0A143BIU9
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1379270:GEMMAAP RS09550
gene id: 1379270:GEMMAAP_RS09550
uniprot id: A0A143BIZ5
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1379270:GEMMAAP RS09715
gene id: 1379270:GEMMAAP_RS09715
uniprot id: A0A143BKQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1379270:GEMMAAP RS10080
gene id: 1379270:GEMMAAP_RS10080
uniprot id: A0A143BKC5
names: Similarity
messages: Belongs to the UPF0102 family.

1379270:GEMMAAP RS06105
gene id: 1379270:GEMMAAP_RS06105
uniprot id: A0A143BIZ4
names: Similarity
messages: Belongs to the peptidase S9C family.

1379270:GEMMAAP RS17630
gene id: 1379270:GEMMAAP_RS17630
uniprot id: A0A145Q5N2
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS12000
gene id: 1379270:GEMMAAP_RS12000
uniprot id: A0A143BL19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1379270:GEMMAAP RS08790
gene id: 1379270:GEMMAAP_RS08790
uniprot id: A0A143BK31
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1379270:GEMMAAP RS02610
gene id: 1379270:GEMMAAP_RS02610
uniprot id: A0A143BHD3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1379270:GEMMAAP RS15445
gene id: 1379270:GEMMAAP_RS15445
uniprot id: A0A143BL88
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1379270:GEMMAAP RS01975
gene id: 1379270:GEMMAAP_RS01975
uniprot id: A0A143BN29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1379270:GEMMAAP RS07705
gene id: 1379270:GEMMAAP_RS07705
uniprot id: A0A143BJH1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1379270:GEMMAAP RS13100
gene id: 1379270:GEMMAAP_RS13100
uniprot id: A0A143BLK1
names: Similarity
messages: Belongs to the peptidase S49 family.

1379270:GEMMAAP RS08595
gene id: 1379270:GEMMAAP_RS08595
uniprot id: A0A143BIJ8
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1379270:GEMMAAP RS06390
gene id: 1379270:GEMMAAP_RS06390
uniprot id: A0A143BJ30
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1379270:GEMMAAP RS12335
gene id: 1379270:GEMMAAP_RS12335
uniprot id: A0A143BK00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1379270:GEMMAAP RS06325
gene id: 1379270:GEMMAAP_RS06325
uniprot id: A0A143BIX7
names: Similarity
messages: Belongs to the threonine aldolase family.

1379270:GEMMAAP RS00515
gene id: 1379270:GEMMAAP_RS00515
uniprot id: A0A143BFF1
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1379270:GEMMAAP RS02910
gene id: 1379270:GEMMAAP_RS02910
uniprot id: A0A143BI20
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS18850
gene id: 1379270:GEMMAAP_RS18850
uniprot id: A0A143BP90
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1379270:GEMMAAP RS15110
gene id: 1379270:GEMMAAP_RS15110
uniprot id: A0A143BL39
names: Similarity
messages: Belongs to the GreA/GreB family.

1379270:GEMMAAP RS16470
gene id: 1379270:GEMMAAP_RS16470
uniprot id: A0A143BN45
names: Similarity
messages: Belongs to the IlvD/Edd family.

1379270:GEMMAAP RS11280
gene id: 1379270:GEMMAAP_RS11280
uniprot id: A0A143BJL5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1379270:GEMMAAP RS15255
gene id: 1379270:GEMMAAP_RS15255
uniprot id: A0A143BMH4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1379270:GEMMAAP RS00640
gene id: 1379270:GEMMAAP_RS00640
uniprot id: A0A143BMV8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1379270:GEMMAAP RS05345
gene id: 1379270:GEMMAAP_RS05345
uniprot id: A0A143BH98
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1379270:GEMMAAP RS07225
gene id: 1379270:GEMMAAP_RS07225
uniprot id: A0A143BJM6
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1379270:GEMMAAP RS07685
gene id: 1379270:GEMMAAP_RS07685
uniprot id: A0A143BJP9
names: Similarity
messages: Belongs to the P(II) protein family.

1379270:GEMMAAP RS19525
gene id: 1379270:GEMMAAP_RS19525
uniprot id: A0A143BP54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1379270:GEMMAAP RS15250
gene id: 1379270:GEMMAAP_RS15250
uniprot id: A0A143BMW6
names: Similarity
messages: Belongs to the cytochrome P450 family.

1379270:GEMMAAP RS11630
gene id: 1379270:GEMMAAP_RS11630
uniprot id: A0A143BP22
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1379270:GEMMAAP RS05255
gene id: 1379270:GEMMAAP_RS05255
uniprot id: A0A143BH88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1379270:GEMMAAP RS05445
gene id: 1379270:GEMMAAP_RS05445
uniprot id: A0A143BII6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1379270:GEMMAAP RS02900
gene id: 1379270:GEMMAAP_RS02900
uniprot id: A0A143BHI9
names: Similarity
messages: Belongs to the peptidase S9C family.

1379270:GEMMAAP RS12525
gene id: 1379270:GEMMAAP_RS12525
uniprot id: A0A143BK32
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1379270:GEMMAAP RS04455
gene id: 1379270:GEMMAAP_RS04455
uniprot id: A0A143BIL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1379270:GEMMAAP RS06680
gene id: 1379270:GEMMAAP_RS06680
uniprot id: A0A143BJ80
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS10495
gene id: 1379270:GEMMAAP_RS10495
uniprot id: A0A143BJ87
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1379270:GEMMAAP RS20590
gene id: 1379270:GEMMAAP_RS20590
uniprot id: A0A143BLJ5
names: Similarity
messages: Belongs to the group II decarboxylase family.

1379270:GEMMAAP RS01810
gene id: 1379270:GEMMAAP_RS01810
uniprot id: A0A143BMZ1
names: Similarity
messages: Belongs to the AHA1 family.

1379270:GEMMAAP RS01100
gene id: 1379270:GEMMAAP_RS01100
uniprot id: A0A143BGS2
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1379270:GEMMAAP RS17690
gene id: 1379270:GEMMAAP_RS17690
uniprot id: A0A143BNM8
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS05290
gene id: 1379270:GEMMAAP_RS05290
uniprot id: A0A143BQ27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1379270:GEMMAAP RS07165
gene id: 1379270:GEMMAAP_RS07165
uniprot id: A0A143BI25
names: Similarity
messages: Belongs to the peptidase U62 family.

1379270:GEMMAAP RS12245
gene id: 1379270:GEMMAAP_RS12245
uniprot id: A0A143BLL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1379270:GEMMAAP RS10440
gene id: 1379270:GEMMAAP_RS10440
uniprot id: A0A143BJB5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1379270:GEMMAAP RS02855
gene id: 1379270:GEMMAAP_RS02855
uniprot id: A0A143BHG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1379270:GEMMAAP RS10405
gene id: 1379270:GEMMAAP_RS10405
uniprot id: A0A143BKJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1379270:GEMMAAP RS12845
gene id: 1379270:GEMMAAP_RS12845
uniprot id: A0A143BLN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1379270:GEMMAAP RS09750
gene id: 1379270:GEMMAAP_RS09750
uniprot id: A0A143BKJ7
names: Similarity
messages: Belongs to the aspartokinase family.

1379270:GEMMAAP RS09665
gene id: 1379270:GEMMAAP_RS09665
uniprot id: A0A143BIY0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS02645
gene id: 1379270:GEMMAAP_RS02645
uniprot id: A0A143BG67
names: Similarity
messages: Belongs to the SufE family.

1379270:GEMMAAP RS04755
gene id: 1379270:GEMMAAP_RS04755
uniprot id: A0A143BH04
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1379270:GEMMAAP RS02820
gene id: 1379270:GEMMAAP_RS02820
uniprot id: A0A143BHG3
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1379270:GEMMAAP RS09955
gene id: 1379270:GEMMAAP_RS09955
uniprot id: A0A143BKD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1379270:GEMMAAP RS05710
gene id: 1379270:GEMMAAP_RS05710
uniprot id: A0A143BHF6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1379270:GEMMAAP RS12265
gene id: 1379270:GEMMAAP_RS12265
uniprot id: A0A143BJU7
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1379270:GEMMAAP RS10065
gene id: 1379270:GEMMAAP_RS10065
uniprot id: A0A143BKP1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1379270:GEMMAAP RS18295
gene id: 1379270:GEMMAAP_RS18295
uniprot id: A0A143BM96
names: Similarity
messages: Belongs to the IMPACT family.

1379270:GEMMAAP RS09855
gene id: 1379270:GEMMAAP_RS09855
uniprot id: A0A143BKR8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1379270:GEMMAAP RS15890
gene id: 1379270:GEMMAAP_RS15890
uniprot id: A0A143BLH5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1379270:GEMMAAP RS17035
gene id: 1379270:GEMMAAP_RS17035
uniprot id: A0A143BLU7
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1379270:GEMMAAP RS06455
gene id: 1379270:GEMMAAP_RS06455
uniprot id: A0A143BIZ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS05110
gene id: 1379270:GEMMAAP_RS05110
uniprot id: A0A143BH50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1379270:GEMMAAP RS09480
gene id: 1379270:GEMMAAP_RS09480
uniprot id: A0A143BKB6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1379270:GEMMAAP RS06445
gene id: 1379270:GEMMAAP_RS06445
uniprot id: A0A143BQ29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1379270:GEMMAAP RS09450
gene id: 1379270:GEMMAAP_RS09450
uniprot id: A0A143BIV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1379270:GEMMAAP RS08290
gene id: 1379270:GEMMAAP_RS08290
uniprot id: A0A143BIE3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS02455
gene id: 1379270:GEMMAAP_RS02455
uniprot id: A0A143BG46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

1379270:GEMMAAP RS10370
gene id: 1379270:GEMMAAP_RS10370
uniprot id: A0A143BKP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1379270:GEMMAAP RS12390
gene id: 1379270:GEMMAAP_RS12390
uniprot id: A0A143BJW4
names: Similarity
messages: Belongs to the GARS family.

1379270:GEMMAAP RS18325
gene id: 1379270:GEMMAAP_RS18325
uniprot id: A0A143BP16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1379270:GEMMAAP RS18320
gene id: 1379270:GEMMAAP_RS18320
uniprot id: A0A143BNW2
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

1379270:GEMMAAP RS00140
gene id: 1379270:GEMMAAP_RS00140
uniprot id: A0A143BH01
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS08540
gene id: 1379270:GEMMAAP_RS08540
uniprot id: A0A143BIM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1379270:GEMMAAP RS03960
gene id: 1379270:GEMMAAP_RS03960
uniprot id: A0A143BIC2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1379270:GEMMAAP RS05295
gene id: 1379270:GEMMAAP_RS05295
uniprot id: A0A143BIJ6
names: Similarity
messages: Belongs to the GSP E family.

1379270:GEMMAAP RS09030
gene id: 1379270:GEMMAAP_RS09030
uniprot id: A0A143BK09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1379270:GEMMAAP RS10305
gene id: 1379270:GEMMAAP_RS10305
uniprot id: A0A143BKF8
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1379270:GEMMAAP RS08485
gene id: 1379270:GEMMAAP_RS08485
uniprot id: A0A143BIL1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1379270:GEMMAAP RS12840
gene id: 1379270:GEMMAAP_RS12840
uniprot id: A0A143BLP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1379270:GEMMAAP RS10735
gene id: 1379270:GEMMAAP_RS10735
uniprot id: A0A143BKW5
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1379270:GEMMAAP RS08535
gene id: 1379270:GEMMAAP_RS08535
uniprot id: A0A143BII5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1379270:GEMMAAP RS01130
gene id: 1379270:GEMMAAP_RS01130
uniprot id: A0A143BFP2
names: Cofactor
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

1379270:GEMMAAP RS09140
gene id: 1379270:GEMMAAP_RS09140
uniprot id: A0A143BIR5
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1379270:GEMMAAP RS10950
gene id: 1379270:GEMMAAP_RS10950
uniprot id: A0A143BJH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1379270:GEMMAAP RS13675
gene id: 1379270:GEMMAAP_RS13675
uniprot id: A0A143BM37
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1379270:GEMMAAP RS06415
gene id: 1379270:GEMMAAP_RS06415
uniprot id: A0A143BHP3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1379270:GEMMAAP RS07870
gene id: 1379270:GEMMAAP_RS07870
uniprot id: A0A143BJR8
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS11550
gene id: 1379270:GEMMAAP_RS11550
uniprot id: A0A143BKY1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1379270:GEMMAAP RS06380
gene id: 1379270:GEMMAAP_RS06380
uniprot id: A0A143BJ06
names: Similarity
messages: Belongs to the CinA family.

1379270:GEMMAAP RS09530
gene id: 1379270:GEMMAAP_RS09530
uniprot id: A0A143BIW1
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1379270:GEMMAAP RS10320
gene id: 1379270:GEMMAAP_RS10320
uniprot id: A0A143BKI3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1379270:GEMMAAP RS04225
gene id: 1379270:GEMMAAP_RS04225
uniprot id: A0A143BGU5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1379270:GEMMAAP RS02420
gene id: 1379270:GEMMAAP_RS02420
uniprot id: A0A143BHA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1379270:GEMMAAP RS03245
gene id: 1379270:GEMMAAP_RS03245
uniprot id: A0A143BHN9
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS00615
gene id: 1379270:GEMMAAP_RS00615
uniprot id: A0A143BFG1
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1379270:GEMMAAP RS05220
gene id: 1379270:GEMMAAP_RS05220
uniprot id: A0A143BIY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1379270:GEMMAAP RS02940
gene id: 1379270:GEMMAAP_RS02940
uniprot id: A0A143BG99
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1379270:GEMMAAP RS09740
gene id: 1379270:GEMMAAP_RS09740
uniprot id: A0A143BJ36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1379270:GEMMAAP RS00350
gene id: 1379270:GEMMAAP_RS00350
uniprot id: A0A143BGH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

1379270:GEMMAAP RS02470
gene id: 1379270:GEMMAAP_RS02470
uniprot id: A0A143BHR9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1379270:GEMMAAP RS09465
gene id: 1379270:GEMMAAP_RS09465
uniprot id: A0A143BIZ6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS15115
gene id: 1379270:GEMMAAP_RS15115
uniprot id: A0A143BL41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1379270:GEMMAAP RS08105
gene id: 1379270:GEMMAAP_RS08105
uniprot id: A0A143BJT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1379270:GEMMAAP RS04160
gene id: 1379270:GEMMAAP_RS04160
uniprot id: A0A143BIF0
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1379270:GEMMAAP RS13315
gene id: 1379270:GEMMAAP_RS13315
uniprot id: A0A143BLP0
names: Similarity
messages: Belongs to the GSP E family.

1379270:GEMMAAP RS09520
gene id: 1379270:GEMMAAP_RS09520
uniprot id: A0A143BIW0
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1379270:GEMMAAP RS04000
gene id: 1379270:GEMMAAP_RS04000
uniprot id: A0A143BIG5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1379270:GEMMAAP RS19785
gene id: 1379270:GEMMAAP_RS19785
uniprot id: A0A143BPM4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1379270:GEMMAAP RS02215
gene id: 1379270:GEMMAAP_RS02215
uniprot id: A0A143BH77
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1379270:GEMMAAP RS03555
gene id: 1379270:GEMMAAP_RS03555
uniprot id: A0A143BHZ7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1379270:GEMMAAP RS06780
gene id: 1379270:GEMMAAP_RS06780
uniprot id: A0A143BJI8
names: Similarity
messages: Belongs to the peptidase S9C family.

1379270:GEMMAAP RS02575
gene id: 1379270:GEMMAAP_RS02575
uniprot id: A0A143BG68
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1379270:GEMMAAP RS13885
gene id: 1379270:GEMMAAP_RS13885
uniprot id: A0A143BM56
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1379270:GEMMAAP RS05080
gene id: 1379270:GEMMAAP_RS05080
uniprot id: A0A143BIW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1379270:GEMMAAP RS02935
gene id: 1379270:GEMMAAP_RS02935
uniprot id: A0A143BGA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1379270:GEMMAAP RS05225
gene id: 1379270:GEMMAAP_RS05225
uniprot id: A0A143BIG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1379270:GEMMAAP RS14070
gene id: 1379270:GEMMAAP_RS14070
uniprot id: A0A143BM91
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1379270:GEMMAAP RS14410
gene id: 1379270:GEMMAAP_RS14410
uniprot id: A0A143BME3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1379270:GEMMAAP RS06130
gene id: 1379270:GEMMAAP_RS06130
uniprot id: A0A143BIU7
names: Similarity
messages: Belongs to the peptidase S9C family.

1379270:GEMMAAP RS13760
gene id: 1379270:GEMMAAP_RS13760
uniprot id: A0A143BM36
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1379270:GEMMAAP RS02925
gene id: 1379270:GEMMAAP_RS02925
uniprot id: A0A143BPG5
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1379270:GEMMAAP RS02785
gene id: 1379270:GEMMAAP_RS02785
uniprot id: A0A143BG87
names: Similarity
messages: Belongs to the peptidase U62 family.

1379270:GEMMAAP RS08710
gene id: 1379270:GEMMAAP_RS08710
uniprot id: A0A143BNP6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1379270:GEMMAAP RS09280
gene id: 1379270:GEMMAAP_RS09280
uniprot id: A0A143BK20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1379270:GEMMAAP RS07095
gene id: 1379270:GEMMAAP_RS07095
uniprot id: A0A143BI01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1379270:GEMMAAP RS03065
gene id: 1379270:GEMMAAP_RS03065
uniprot id: A0A143BHS9
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1379270:GEMMAAP RS00240
gene id: 1379270:GEMMAAP_RS00240
uniprot id: A0A143BFB6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1379270:GEMMAAP RS03425
gene id: 1379270:GEMMAAP_RS03425
uniprot id: A0A143BGG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1379270:GEMMAAP RS16750
gene id: 1379270:GEMMAAP_RS16750
uniprot id: A0A143BLQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1379270:GEMMAAP RS06200
gene id: 1379270:GEMMAAP_RS06200
uniprot id: A0A143BIV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1379270:GEMMAAP RS12535
gene id: 1379270:GEMMAAP_RS12535
uniprot id: A0A143BLI7
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1379270:GEMMAAP RS01480
gene id: 1379270:GEMMAAP_RS01480
uniprot id: A0A143BFT1
names: Similarity
messages: Belongs to the glutamine synthetase family.

1379270:GEMMAAP RS14365
gene id: 1379270:GEMMAAP_RS14365
uniprot id: A0A143BMC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm

1379270:GEMMAAP RS06465
gene id: 1379270:GEMMAAP_RS06465
uniprot id: A0A143BQ70
names: Similarity
messages: Belongs to the geranylgeranyl reductase family. ChlP subfamily.

1379270:GEMMAAP RS11425
gene id: 1379270:GEMMAAP_RS11425
uniprot id: A0A143BJJ0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS15040
gene id: 1379270:GEMMAAP_RS15040
uniprot id: A0A143BMT9
names: Cofactor
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.

1379270:GEMMAAP RS07395
gene id: 1379270:GEMMAAP_RS07395
uniprot id: A0A143BJI7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1379270:GEMMAAP RS19590
gene id: 1379270:GEMMAAP_RS19590
uniprot id: A0A143BP70
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1379270:GEMMAAP RS06290
gene id: 1379270:GEMMAAP_RS06290
uniprot id: A0A143BHP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1379270:GEMMAAP RS10560
gene id: 1379270:GEMMAAP_RS10560
uniprot id: A0A143BJ93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1379270:GEMMAAP RS02415
gene id: 1379270:GEMMAAP_RS02415
uniprot id: A0A143BN88
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1379270:GEMMAAP RS03735
gene id: 1379270:GEMMAAP_RS03735
uniprot id: A0A143BHU5
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS05215
gene id: 1379270:GEMMAAP_RS05215
uniprot id: A0A143BPR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1379270:GEMMAAP RS09555
gene id: 1379270:GEMMAAP_RS09555
uniprot id: A0A143BKH2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1379270:GEMMAAP RS12170
gene id: 1379270:GEMMAAP_RS12170
uniprot id: A0A143BJU0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1379270:GEMMAAP RS04095
gene id: 1379270:GEMMAAP_RS04095
uniprot id: A0A143BIE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1379270:GEMMAAP RS08050
gene id: 1379270:GEMMAAP_RS08050
uniprot id: A0A143BJT6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1379270:GEMMAAP RS13575
gene id: 1379270:GEMMAAP_RS13575
uniprot id: A0A143BKE8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1379270:GEMMAAP RS10335
gene id: 1379270:GEMMAAP_RS10335
uniprot id: A0A143BJ70
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS04445
gene id: 1379270:GEMMAAP_RS04445
uniprot id: A0A143BIA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1379270:GEMMAAP RS01330
gene id: 1379270:GEMMAAP_RS01330
uniprot id: A0A143BGV1
names: Similarity
messages: Belongs to the peptidase S51 family.

1379270:GEMMAAP RS08370
gene id: 1379270:GEMMAAP_RS08370
uniprot id: A0A143BII0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1379270:GEMMAAP RS12395
gene id: 1379270:GEMMAAP_RS12395
uniprot id: A0A143BK19
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Monomer.

1379270:GEMMAAP RS07930
gene id: 1379270:GEMMAAP_RS07930
uniprot id: A0A143BNW1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1379270:GEMMAAP RS03410
gene id: 1379270:GEMMAAP_RS03410
uniprot id: A0A143BHQ6
names: Similarity
messages: Belongs to the peptidase S33 family.

1379270:GEMMAAP RS13330
gene id: 1379270:GEMMAAP_RS13330
uniprot id: A0A143BKB0
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS13810
gene id: 1379270:GEMMAAP_RS13810
uniprot id: A0A143BM46
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1379270:GEMMAAP RS00165
gene id: 1379270:GEMMAAP_RS00165
uniprot id: A0A143BFA4
names: Similarity
messages: Belongs to the ParB family.

1379270:GEMMAAP RS02275
gene id: 1379270:GEMMAAP_RS02275
uniprot id: A0A143BHN6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1379270:GEMMAAP RS09495
gene id: 1379270:GEMMAAP_RS09495
uniprot id: A0A143BK49
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1379270:GEMMAAP RS07610
gene id: 1379270:GEMMAAP_RS07610
uniprot id: A0A143BIA1
names: Similarity
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1379270:GEMMAAP RS09180
gene id: 1379270:GEMMAAP_RS09180
uniprot id: A0A143BKA2
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1379270:GEMMAAP RS13440
gene id: 1379270:GEMMAAP_RS13440
uniprot id: A0A143BLR4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1379270:GEMMAAP RS08085
gene id: 1379270:GEMMAAP_RS08085
uniprot id: A0A143BIA6
names: Subcellular Location Annotation
messages: Cytoplasm

1379270:GEMMAAP RS09605
gene id: 1379270:GEMMAAP_RS09605
uniprot id: A0A143BIX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1379270:GEMMAAP RS03295
gene id: 1379270:GEMMAAP_RS03295
uniprot id: A0A143BI32
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS16535
gene id: 1379270:GEMMAAP_RS16535
uniprot id: A0A143BN55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1379270:GEMMAAP RS01970
gene id: 1379270:GEMMAAP_RS01970
uniprot id: A0A143BH37
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1379270:GEMMAAP RS04765
gene id: 1379270:GEMMAAP_RS04765
uniprot id: A0A143BH08
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1379270:GEMMAAP RS13920
gene id: 1379270:GEMMAAP_RS13920
uniprot id: A0A143BMC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1379270:GEMMAAP RS04450
gene id: 1379270:GEMMAAP_RS04450
uniprot id: A0A143BI23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1379270:GEMMAAP RS09500
gene id: 1379270:GEMMAAP_RS09500
uniprot id: A0A143BKM5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1379270:GEMMAAP RS18695
gene id: 1379270:GEMMAAP_RS18695
uniprot id: A0A143BP11
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS14850
gene id: 1379270:GEMMAAP_RS14850
uniprot id: A0A143BL02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1379270:GEMMAAP RS12980
gene id: 1379270:GEMMAAP_RS12980
uniprot id: A0A143BK63
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1379270:GEMMAAP RS07945
gene id: 1379270:GEMMAAP_RS07945
uniprot id: A0A143BIB6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1379270:GEMMAAP RS12575
gene id: 1379270:GEMMAAP_RS12575
uniprot id: A0A143BJZ9
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1379270:GEMMAAP RS11625
gene id: 1379270:GEMMAAP_RS11625
uniprot id: A0A143BL36
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1379270:GEMMAAP RS03235
gene id: 1379270:GEMMAAP_RS03235
uniprot id: A0A143BHN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1379270:GEMMAAP RS05185
gene id: 1379270:GEMMAAP_RS05185
uniprot id: A0A143BIU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1379270:GEMMAAP RS14990
gene id: 1379270:GEMMAAP_RS14990
uniprot id: A0A143BL21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1379270:GEMMAAP RS09070
gene id: 1379270:GEMMAAP_RS09070
uniprot id: A0A143BKB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1379270:GEMMAAP RS00210
gene id: 1379270:GEMMAAP_RS00210
uniprot id: A0A143BGG0
names: Similarity
messages: Belongs to the ArsC family.

1379270:GEMMAAP RS07205
gene id: 1379270:GEMMAAP_RS07205
uniprot id: A0A143BI18
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS09290
gene id: 1379270:GEMMAAP_RS09290
uniprot id: A0A143BK42
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1379270:GEMMAAP RS07615
gene id: 1379270:GEMMAAP_RS07615
uniprot id: A0A143BI79
names: Similarity
messages: Belongs to the threonine synthase family.

1379270:GEMMAAP RS15510
gene id: 1379270:GEMMAAP_RS15510
uniprot id: A0A143BL92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1379270:GEMMAAP RS09970
gene id: 1379270:GEMMAAP_RS09970
uniprot id: A0A143BJ19
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1379270:GEMMAAP RS06955
gene id: 1379270:GEMMAAP_RS06955
uniprot id: A0A143BJH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1379270:GEMMAAP RS10640
gene id: 1379270:GEMMAAP_RS10640
uniprot id: A0A143BKL8
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

1379270:GEMMAAP RS00920
gene id: 1379270:GEMMAAP_RS00920
uniprot id: A0A143BFJ7
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS20945
gene id: 1379270:GEMMAAP_RS20945
uniprot id: A0A143BK78
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1379270:GEMMAAP RS09185
gene id: 1379270:GEMMAAP_RS09185
uniprot id: A0A143BK11
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1379270:GEMMAAP RS01230
gene id: 1379270:GEMMAAP_RS01230
uniprot id: A0A143BGW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1379270:GEMMAAP RS07195
gene id: 1379270:GEMMAAP_RS07195
uniprot id: A0A143BJC2
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

1379270:GEMMAAP RS11415
gene id: 1379270:GEMMAAP_RS11415
uniprot id: A0A143BLA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1379270:GEMMAAP RS07415
gene id: 1379270:GEMMAAP_RS07415
uniprot id: A0A143BJV1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1379270:GEMMAAP RS07605
gene id: 1379270:GEMMAAP_RS07605
uniprot id: A0A143BI49
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1379270:GEMMAAP RS07915
gene id: 1379270:GEMMAAP_RS07915
uniprot id: A0A143BI88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1379270:GEMMAAP RS01900
gene id: 1379270:GEMMAAP_RS01900
uniprot id: A0A143BHN7
names: Similarity
messages: Belongs to the AHA1 family.

1379270:GEMMAAP RS00010
gene id: 1379270:GEMMAAP_RS00010
uniprot id: A0A143BES9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1379270:GEMMAAP RS02450
gene id: 1379270:GEMMAAP_RS02450
uniprot id: A0A143BG53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1379270:GEMMAAP RS15075
gene id: 1379270:GEMMAAP_RS15075
uniprot id: A0A143BMR8
names: Cofactor
messages: Binds 1 FAD per subunit.

1379270:GEMMAAP RS18790
gene id: 1379270:GEMMAAP_RS18790
uniprot id: A0A143BPA0
names: Similarity
messages: Belongs to the creatininase superfamily.

1379270:GEMMAAP RS09650
gene id: 1379270:GEMMAAP_RS09650
uniprot id: A0A143BK71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1379270:GEMMAAP RS16080
gene id: 1379270:GEMMAAP_RS16080
uniprot id: A0A143BLH0
names: Similarity
messages: Belongs to the YciI family.

1379270:GEMMAAP RS00780
gene id: 1379270:GEMMAAP_RS00780
uniprot id: A0A143BFI0
names: Similarity
messages: Belongs to the SCO1/2 family.

1379270:GEMMAAP RS14290
gene id: 1379270:GEMMAAP_RS14290
uniprot id: A0A143BM06
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1379270:GEMMAAP RS05145
gene id: 1379270:GEMMAAP_RS05145
uniprot id: A0A143BID6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1379270:GEMMAAP RS13565
gene id: 1379270:GEMMAAP_RS13565
uniprot id: A0A143BLT2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS09060
gene id: 1379270:GEMMAAP_RS09060
uniprot id: A0A143BIU2
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS10055
gene id: 1379270:GEMMAAP_RS10055
uniprot id: A0A143BJ72
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1379270:GEMMAAP RS01085
gene id: 1379270:GEMMAAP_RS01085
uniprot id: A0A143BFM1
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

1379270:GEMMAAP RS16315
gene id: 1379270:GEMMAAP_RS16315
uniprot id: A0A143BN85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1379270:GEMMAAP RS10160
gene id: 1379270:GEMMAAP_RS10160
uniprot id: A0A143BKG3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1379270:GEMMAAP RS15420
gene id: 1379270:GEMMAAP_RS15420
uniprot id: A0A143BMF6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1379270:GEMMAAP RS09600
gene id: 1379270:GEMMAAP_RS09600
uniprot id: A0A143BIX3
names: Similarity
messages: Belongs to the MreC family.

1379270:GEMMAAP RS09320
gene id: 1379270:GEMMAAP_RS09320
uniprot id: A0A143BK99
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1379270:GEMMAAP RS18105
gene id: 1379270:GEMMAAP_RS18105
uniprot id: A0A143BMC5
names: Similarity
messages: Belongs to the ArsC family.

1379270:GEMMAAP RS11945
gene id: 1379270:GEMMAAP_RS11945
uniprot id: A0A143BL34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1379270:GEMMAAP RS04975
gene id: 1379270:GEMMAAP_RS04975
uniprot id: A0A143BIF5
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1379270:GEMMAAP RS05090
gene id: 1379270:GEMMAAP_RS05090
uniprot id: A0A143BIE1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1379270:GEMMAAP RS06740
gene id: 1379270:GEMMAAP_RS06740
uniprot id: A0A143BJ58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

1379270:GEMMAAP RS02870
gene id: 1379270:GEMMAAP_RS02870
uniprot id: A0A143BG93
names: Similarity
messages: Belongs to the glycosyl hydrolase 100 family.

1379270:GEMMAAP RS11505
gene id: 1379270:GEMMAAP_RS11505
uniprot id: A0A143BNY0
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS15870
gene id: 1379270:GEMMAAP_RS15870
uniprot id: A0A143BMQ3
names: Similarity
messages: Belongs to the group II decarboxylase family.

1379270:GEMMAAP RS06635
gene id: 1379270:GEMMAAP_RS06635
uniprot id: A0A143BJG9
names: Function
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.
messages: Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.

1379270:GEMMAAP RS02780
gene id: 1379270:GEMMAAP_RS02780
uniprot id: A0A143BG92
names: Similarity
messages: Belongs to the peptidase U62 family.

1379270:GEMMAAP RS15095
gene id: 1379270:GEMMAAP_RS15095
uniprot id: A0A143BMC2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1379270:GEMMAAP RS18620
gene id: 1379270:GEMMAAP_RS18620
uniprot id: A0A143BP57
names: Similarity
messages: Belongs to the SusD family.

1379270:GEMMAAP RS18650
gene id: 1379270:GEMMAAP_RS18650
uniprot id: A0A143BPK4
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS09735
gene id: 1379270:GEMMAAP_RS09735
uniprot id: A0A143BIZ0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1379270:GEMMAAP RS00925
gene id: 1379270:GEMMAAP_RS00925
uniprot id: A0A143BMZ4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

1379270:GEMMAAP RS01095
gene id: 1379270:GEMMAAP_RS01095
uniprot id: A0A143BH75
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1379270:GEMMAAP RS09490
gene id: 1379270:GEMMAAP_RS09490
uniprot id: A0A143BKE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1379270:GEMMAAP RS13305
gene id: 1379270:GEMMAAP_RS13305
uniprot id: A0A143BLL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

1379270:GEMMAAP RS12450
gene id: 1379270:GEMMAAP_RS12450
uniprot id: A0A143BJX9
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1379270:GEMMAAP RS12150
gene id: 1379270:GEMMAAP_RS12150
uniprot id: A0A143BLK3
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1379270:GEMMAAP RS01235
gene id: 1379270:GEMMAAP_RS01235
uniprot id: A0A143BHE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1379270:GEMMAAP RS17680
gene id: 1379270:GEMMAAP_RS17680
uniprot id: A0A143BM65
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1379270:GEMMAAP RS06590
gene id: 1379270:GEMMAAP_RS06590
uniprot id: A0A143BHS7
names: Function
messages: Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.

1379270:GEMMAAP RS05440
gene id: 1379270:GEMMAAP_RS05440
uniprot id: A0A143BIP7
names: Similarity
messages: Belongs to the histone deacetylase family.

1379270:GEMMAAP RS06935
gene id: 1379270:GEMMAAP_RS06935
uniprot id: A0A143BHW8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1379270:GEMMAAP RS13495
gene id: 1379270:GEMMAAP_RS13495
uniprot id: A0A143BLY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1379270:GEMMAAP RS05075
gene id: 1379270:GEMMAAP_RS05075
uniprot id: A0A143BIC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1379270:GEMMAAP RS09745
gene id: 1379270:GEMMAAP_RS09745
uniprot id: A0A143BJ24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1379270:GEMMAAP RS03370
gene id: 1379270:GEMMAAP_RS03370
uniprot id: A0A143BGF0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1379270:GEMMAAP RS18975
gene id: 1379270:GEMMAAP_RS18975
uniprot id: A0A143BP48
names: Similarity
messages: Belongs to the AHA1 family.

1379270:GEMMAAP RS14745
gene id: 1379270:GEMMAAP_RS14745
uniprot id: A0A143BMB6
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS09680
gene id: 1379270:GEMMAAP_RS09680
uniprot id: A0A143BJ16
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1379270:GEMMAAP RS13680
gene id: 1379270:GEMMAAP_RS13680
uniprot id: A0A143BM19
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS09980
gene id: 1379270:GEMMAAP_RS09980
uniprot id: A0A143BJ66
names: Similarity
messages: Belongs to the DprA/Smf family.

1379270:GEMMAAP RS12770
gene id: 1379270:GEMMAAP_RS12770
uniprot id: A0A143BLN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1379270:GEMMAAP RS11965
gene id: 1379270:GEMMAAP_RS11965
uniprot id: A0A143BJV9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1379270:GEMMAAP RS09795
gene id: 1379270:GEMMAAP_RS09795
uniprot id: A0A143BJ04
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1379270:GEMMAAP RS14190
gene id: 1379270:GEMMAAP_RS14190
uniprot id: A0A143BM99
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS05535
gene id: 1379270:GEMMAAP_RS05535
uniprot id: A0A143BHA7
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1379270:GEMMAAP RS09670
gene id: 1379270:GEMMAAP_RS09670
uniprot id: A0A143BIY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1379270:GEMMAAP RS14820
gene id: 1379270:GEMMAAP_RS14820
uniprot id: A0A143BMI0
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

1379270:GEMMAAP RS06670
gene id: 1379270:GEMMAAP_RS06670
uniprot id: A0A143BJD6
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS13925
gene id: 1379270:GEMMAAP_RS13925
uniprot id: A0A143BLY8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1379270:GEMMAAP RS15345
gene id: 1379270:GEMMAAP_RS15345
uniprot id: A0A143BMX6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. POR subfamily.

1379270:GEMMAAP RS09860
gene id: 1379270:GEMMAAP_RS09860
uniprot id: A0A143BKC4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1379270:GEMMAAP RS10925
gene id: 1379270:GEMMAAP_RS10925
uniprot id: A0A143BL57
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1379270:GEMMAAP RS14130
gene id: 1379270:GEMMAAP_RS14130
uniprot id: A0A143BMA1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1379270:GEMMAAP RS16540
gene id: 1379270:GEMMAAP_RS16540
uniprot id: A0A143BPD2
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS09825
gene id: 1379270:GEMMAAP_RS09825
uniprot id: A0A143BKK6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS07800
gene id: 1379270:GEMMAAP_RS07800
uniprot id: A0A143BJI2
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1379270:GEMMAAP RS11115
gene id: 1379270:GEMMAAP_RS11115
uniprot id: A0A143BJF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1379270:GEMMAAP RS05105
gene id: 1379270:GEMMAAP_RS05105
uniprot id: A0A143BQ17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1379270:GEMMAAP RS06890
gene id: 1379270:GEMMAAP_RS06890
uniprot id: A0A143BJG2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1379270:GEMMAAP RS15760
gene id: 1379270:GEMMAAP_RS15760
uniprot id: A0A143BMX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1379270:GEMMAAP RS19050
gene id: 1379270:GEMMAAP_RS19050
uniprot id: A0A143BQV9
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1379270:GEMMAAP RS10385
gene id: 1379270:GEMMAAP_RS10385
uniprot id: A0A143BP39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1379270:GEMMAAP RS06180
gene id: 1379270:GEMMAAP_RS06180
uniprot id: A0A143BIX8
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1379270:GEMMAAP RS03890
gene id: 1379270:GEMMAAP_RS03890
uniprot id: A0A143BGN5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS11180
gene id: 1379270:GEMMAAP_RS11180
uniprot id: A0A143BNX0
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1379270:GEMMAAP RS05300
gene id: 1379270:GEMMAAP_RS05300
uniprot id: A0A143BPS3
names: Similarity
messages: Belongs to the DapA family.

1379270:GEMMAAP RS14830
gene id: 1379270:GEMMAAP_RS14830
uniprot id: A0A145Q4V4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

1379270:GEMMAAP RS15000
gene id: 1379270:GEMMAAP_RS15000
uniprot id: A0A143BL59
names: Similarity
messages: Belongs to the Fur family.

1379270:GEMMAAP RS14115
gene id: 1379270:GEMMAAP_RS14115
uniprot id: A0A143BKS3
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS16560
gene id: 1379270:GEMMAAP_RS16560
uniprot id: A0A143BNE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1379270:GEMMAAP RS07635
gene id: 1379270:GEMMAAP_RS07635
uniprot id: A0A143BJG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

1379270:GEMMAAP RS10100
gene id: 1379270:GEMMAAP_RS10100
uniprot id: A0A143BJ39
names: Similarity
messages: Belongs to the ComB family.

1379270:GEMMAAP RS17745
gene id: 1379270:GEMMAAP_RS17745
uniprot id: A0A143BM20
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1379270:GEMMAAP RS09595
gene id: 1379270:GEMMAAP_RS09595
uniprot id: A0A143BK86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1379270:GEMMAAP RS07370
gene id: 1379270:GEMMAAP_RS07370
uniprot id: A0A143BI26
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1379270:GEMMAAP RS10105
gene id: 1379270:GEMMAAP_RS10105
uniprot id: A0A143BJ40
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1379270:GEMMAAP RS10990
gene id: 1379270:GEMMAAP_RS10990
uniprot id: A0A143BKW0
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS11915
gene id: 1379270:GEMMAAP_RS11915
uniprot id: A0A143BJU2
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1379270:GEMMAAP RS14530
gene id: 1379270:GEMMAAP_RS14530
uniprot id: A0A143BML4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1379270:GEMMAAP RS19100
gene id: 1379270:GEMMAAP_RS19100
uniprot id: A0A143BMJ4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1379270:GEMMAAP RS03240
gene id: 1379270:GEMMAAP_RS03240
uniprot id: A0A143BHV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1379270:GEMMAAP RS05155
gene id: 1379270:GEMMAAP_RS05155
uniprot id: A0A143BIF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1379270:GEMMAAP RS05200
gene id: 1379270:GEMMAAP_RS05200
uniprot id: A0A143BPN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1379270:GEMMAAP RS07975
gene id: 1379270:GEMMAAP_RS07975
uniprot id: A0A145Q2R2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS18025
gene id: 1379270:GEMMAAP_RS18025
uniprot id: A0A143BM83
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1379270:GEMMAAP RS06060
gene id: 1379270:GEMMAAP_RS06060
uniprot id: A0A143BIT8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1379270:GEMMAAP RS09200
gene id: 1379270:GEMMAAP_RS09200
uniprot id: A0A143BK28
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1379270:GEMMAAP RS17275
gene id: 1379270:GEMMAAP_RS17275
uniprot id: A0A143BLW2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1379270:GEMMAAP RS11145
gene id: 1379270:GEMMAAP_RS11145
uniprot id: A0A143BKZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1379270:GEMMAAP RS01115
gene id: 1379270:GEMMAAP_RS01115
uniprot id: A0A143BHC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1379270:GEMMAAP RS04440
gene id: 1379270:GEMMAAP_RS04440
uniprot id: A0A143BI46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1379270:GEMMAAP RS18655
gene id: 1379270:GEMMAAP_RS18655
uniprot id: A0A143BP81
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS02400
gene id: 1379270:GEMMAAP_RS02400
uniprot id: A0A143BG34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1379270:GEMMAAP RS09015
gene id: 1379270:GEMMAAP_RS09015
uniprot id: A0A143BJZ2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1379270:GEMMAAP RS16435
gene id: 1379270:GEMMAAP_RS16435
uniprot id: A0A143BLQ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1379270:GEMMAAP RS08940
gene id: 1379270:GEMMAAP_RS08940
uniprot id: A0A143BKG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1379270:GEMMAAP RS03885
gene id: 1379270:GEMMAAP_RS03885
uniprot id: A0A143BGM7
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1379270:GEMMAAP RS13055
gene id: 1379270:GEMMAAP_RS13055
uniprot id: A0A143BKB8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1379270:GEMMAAP RS00015
gene id: 1379270:GEMMAAP_RS00015
uniprot id: A0A143BES7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1379270:GEMMAAP RS18755
gene id: 1379270:GEMMAAP_RS18755
uniprot id: A0A143BMC9
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS04015
gene id: 1379270:GEMMAAP_RS04015
uniprot id: A0A143BGP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1379270:GEMMAAP RS14985
gene id: 1379270:GEMMAAP_RS14985
uniprot id: A0A143BMD8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1379270:GEMMAAP RS09190
gene id: 1379270:GEMMAAP_RS09190
uniprot id: A0A143BKJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1379270:GEMMAAP RS08055
gene id: 1379270:GEMMAAP_RS08055
uniprot id: A0A143BJK9
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1379270:GEMMAAP RS09215
gene id: 1379270:GEMMAAP_RS09215
uniprot id: A0A143BIS5
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1379270:GEMMAAP RS01430
gene id: 1379270:GEMMAAP_RS01430
uniprot id: A0A143BGX5
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1379270:GEMMAAP RS01225
gene id: 1379270:GEMMAAP_RS01225
uniprot id: A0A143BH56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1379270:GEMMAAP RS09660
gene id: 1379270:GEMMAAP_RS09660
uniprot id: A0A143BK93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1379270:GEMMAAP RS19875
gene id: 1379270:GEMMAAP_RS19875
uniprot id: A0A145Q6B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1379270:GEMMAAP RS08185
gene id: 1379270:GEMMAAP_RS08185
uniprot id: A0A143BK48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1379270:GEMMAAP RS14900
gene id: 1379270:GEMMAAP_RS14900
uniprot id: A0A143BMN2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1379270:GEMMAAP RS12195
gene id: 1379270:GEMMAAP_RS12195
uniprot id: A0A143BLC9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1379270:GEMMAAP RS15455
gene id: 1379270:GEMMAAP_RS15455
uniprot id: A0A143BL85
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1379270:GEMMAAP RS16060
gene id: 1379270:GEMMAAP_RS16060
uniprot id: A0A143BN79
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS04695
gene id: 1379270:GEMMAAP_RS04695
uniprot id: A0A143BGZ3
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS05455
gene id: 1379270:GEMMAAP_RS05455
uniprot id: A0A143BJ12
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1379270:GEMMAAP RS04630
gene id: 1379270:GEMMAAP_RS04630
uniprot id: A0A143BI72
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1379270:GEMMAAP RS10150
gene id: 1379270:GEMMAAP_RS10150
uniprot id: A0A143BKD5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1379270:GEMMAAP RS06990
gene id: 1379270:GEMMAAP_RS06990
uniprot id: A0A143BHX8
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1379270:GEMMAAP RS08845
gene id: 1379270:GEMMAAP_RS08845
uniprot id: A0A143BIR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1379270:GEMMAAP RS06230
gene id: 1379270:GEMMAAP_RS06230
uniprot id: A0A143BHL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1379270:GEMMAAP RS08730
gene id: 1379270:GEMMAAP_RS08730
uniprot id: A0A143BK43
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

1379270:GEMMAAP RS00290
gene id: 1379270:GEMMAAP_RS00290
uniprot id: A0A143BGI2
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1379270:GEMMAAP RS12690
gene id: 1379270:GEMMAAP_RS12690
uniprot id: A0A143BLL6
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

1379270:GEMMAAP RS08830
gene id: 1379270:GEMMAAP_RS08830
uniprot id: A0A143BIL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1379270:GEMMAAP RS09245
gene id: 1379270:GEMMAAP_RS09245
uniprot id: A0A143BIV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1379270:GEMMAAP RS18580
gene id: 1379270:GEMMAAP_RS18580
uniprot id: A0A143BNS2
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS01240
gene id: 1379270:GEMMAAP_RS01240
uniprot id: A0A143BGU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1379270:GEMMAAP RS06500
gene id: 1379270:GEMMAAP_RS06500
uniprot id: A0A143BPW7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ChlB/BchB/BchZ family.
messages: Binds 1 [4Fe-4S] cluster per heterodimer. The cluster is bound at the heterodimer interface by residues from both subunits.
messages: Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.
messages: Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB. Forms a heterotetramer of two BchB and two BchN subunits.

1379270:GEMMAAP RS04155
gene id: 1379270:GEMMAAP_RS04155
uniprot id: A0A143BGT4
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1379270:GEMMAAP RS02305
gene id: 1379270:GEMMAAP_RS02305
uniprot id: A0A143BH79
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1379270:GEMMAAP RS09160
gene id: 1379270:GEMMAAP_RS09160
uniprot id: A0A143BKC3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1379270:GEMMAAP RS17300
gene id: 1379270:GEMMAAP_RS17300
uniprot id: A0A143BNP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1379270:GEMMAAP RS06660
gene id: 1379270:GEMMAAP_RS06660
uniprot id: A0A143BHT6
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS10390
gene id: 1379270:GEMMAAP_RS10390
uniprot id: A0A143BKG9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

1379270:GEMMAAP RS12585
gene id: 1379270:GEMMAAP_RS12585
uniprot id: A0A143BK41
names: Similarity
messages: Belongs to the SusD family.

1379270:GEMMAAP RS18835
gene id: 1379270:GEMMAAP_RS18835
uniprot id: A0A143BME0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1379270:GEMMAAP RS04945
gene id: 1379270:GEMMAAP_RS04945
uniprot id: A0A143BIC0
names: Similarity
messages: Belongs to the Nth/MutY family.

1379270:GEMMAAP RS04180
gene id: 1379270:GEMMAAP_RS04180
uniprot id: A0A143BHZ4
names: Similarity
messages: Belongs to the FPG family.

1379270:GEMMAAP RS10300
gene id: 1379270:GEMMAAP_RS10300
uniprot id: A0A143BKP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1379270:GEMMAAP RS04960
gene id: 1379270:GEMMAAP_RS04960
uniprot id: A0A143BH38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1379270:GEMMAAP RS09965
gene id: 1379270:GEMMAAP_RS09965
uniprot id: A0A143BJ20
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1379270:GEMMAAP RS12795
gene id: 1379270:GEMMAAP_RS12795
uniprot id: A0A143BLU2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1379270:GEMMAAP RS13460
gene id: 1379270:GEMMAAP_RS13460
uniprot id: A0A143BKI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1379270:GEMMAAP RS07150
gene id: 1379270:GEMMAAP_RS07150
uniprot id: A0A143BI36
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1379270:GEMMAAP RS12035
gene id: 1379270:GEMMAAP_RS12035
uniprot id: A0A143BJW8
names: Similarity
messages: Belongs to the UPF0111 family.

1379270:GEMMAAP RS05260
gene id: 1379270:GEMMAAP_RS05260
uniprot id: A0A143BH95
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1379270:GEMMAAP RS16325
gene id: 1379270:GEMMAAP_RS16325
uniprot id: A0A143BMT5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1379270:GEMMAAP RS00505
gene id: 1379270:GEMMAAP_RS00505
uniprot id: A0A143BH51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1379270:GEMMAAP RS00055
gene id: 1379270:GEMMAAP_RS00055
uniprot id: A0A143BGQ3
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1379270:GEMMAAP RS11925
gene id: 1379270:GEMMAAP_RS11925
uniprot id: A0A143BL76
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1379270:GEMMAAP RS02065
gene id: 1379270:GEMMAAP_RS02065
uniprot id: A0A143BH54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1379270:GEMMAAP RS00180
gene id: 1379270:GEMMAAP_RS00180
uniprot id: A0A143BN26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1379270:GEMMAAP RS12380
gene id: 1379270:GEMMAAP_RS12380
uniprot id: A0A143BJX7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1379270:GEMMAAP RS03420
gene id: 1379270:GEMMAAP_RS03420
uniprot id: A0A143BHP8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1379270:GEMMAAP RS01125
gene id: 1379270:GEMMAAP_RS01125
uniprot id: A0A143BGS4
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1379270:GEMMAAP RS13470
gene id: 1379270:GEMMAAP_RS13470
uniprot id: A0A143BKG7
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS07575
gene id: 1379270:GEMMAAP_RS07575
uniprot id: A0A143BJF5
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1379270:GEMMAAP RS07530
gene id: 1379270:GEMMAAP_RS07530
uniprot id: A0A143BI40
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS16805
gene id: 1379270:GEMMAAP_RS16805
uniprot id: A0A143BN30
names: Similarity
messages: Belongs to the YjdM family.

1379270:GEMMAAP RS01485
gene id: 1379270:GEMMAAP_RS01485
uniprot id: A0A143BPH3
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1379270:GEMMAAP RS12190
gene id: 1379270:GEMMAAP_RS12190
uniprot id: A0A143BLF6
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS08715
gene id: 1379270:GEMMAAP_RS08715
uniprot id: A0A143BIP0
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS12780
gene id: 1379270:GEMMAAP_RS12780
uniprot id: A0A143BQQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1379270:GEMMAAP RS09580
gene id: 1379270:GEMMAAP_RS09580
uniprot id: A0A143BK61
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1379270:GEMMAAP RS17295
gene id: 1379270:GEMMAAP_RS17295
uniprot id: A0A143BN51
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1379270:GEMMAAP RS16820
gene id: 1379270:GEMMAAP_RS16820
uniprot id: A0A143BLR6
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1379270:GEMMAAP RS01570
gene id: 1379270:GEMMAAP_RS01570
uniprot id: A0A143BHE4
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

1379270:GEMMAAP RS02375
gene id: 1379270:GEMMAAP_RS02375
uniprot id: A0A143BHV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1379270:GEMMAAP RS14825
gene id: 1379270:GEMMAAP_RS14825
uniprot id: A0A143BM89
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

1379270:GEMMAAP RS01280
gene id: 1379270:GEMMAAP_RS01280
uniprot id: A0A143BHA3
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1379270:GEMMAAP RS05530
gene id: 1379270:GEMMAAP_RS05530
uniprot id: A0A143BIJ7
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

1379270:GEMMAAP RS07215
gene id: 1379270:GEMMAAP_RS07215
uniprot id: A0A143BI47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1379270:GEMMAAP RS08160
gene id: 1379270:GEMMAAP_RS08160
uniprot id: A0A143BJT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1379270:GEMMAAP RS03560
gene id: 1379270:GEMMAAP_RS03560
uniprot id: A0A143BHS3
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1379270:GEMMAAP RS16300
gene id: 1379270:GEMMAAP_RS16300
uniprot id: A0A143BLN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

1379270:GEMMAAP RS05195
gene id: 1379270:GEMMAAP_RS05195
uniprot id: A0A143BIL9
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1379270:GEMMAAP RS12670
gene id: 1379270:GEMMAAP_RS12670
uniprot id: A0A143BLL9
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS04005
gene id: 1379270:GEMMAAP_RS04005
uniprot id: A0A143BHY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1379270:GEMMAAP RS12955
gene id: 1379270:GEMMAAP_RS12955
uniprot id: A0A143BLQ9
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1379270:GEMMAAP RS05935
gene id: 1379270:GEMMAAP_RS05935
uniprot id: A0A143BHH6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

1379270:GEMMAAP RS04210
gene id: 1379270:GEMMAAP_RS04210
uniprot id: A0A143BGS0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS14110
gene id: 1379270:GEMMAAP_RS14110
uniprot id: A0A143BKL7
names: Similarity
messages: Belongs to the asparagine synthetase family.

1379270:GEMMAAP RS09505
gene id: 1379270:GEMMAAP_RS09505
uniprot id: A0A143BK75
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1379270:GEMMAAP RS02365
gene id: 1379270:GEMMAAP_RS02365
uniprot id: A0A143BHJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

1379270:GEMMAAP RS09435
gene id: 1379270:GEMMAAP_RS09435
uniprot id: A0A143BKL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1379270:GEMMAAP RS04810
gene id: 1379270:GEMMAAP_RS04810
uniprot id: A0A143BH13
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1379270:GEMMAAP RS06585
gene id: 1379270:GEMMAAP_RS06585
uniprot id: A0A143BHR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reaction center PufL/M/PsbA/D family.
messages: Membrane
messages: The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis.

1379270:GEMMAAP RS05230
gene id: 1379270:GEMMAAP_RS05230
uniprot id: A0A143BH68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1379270:GEMMAAP RS07715
gene id: 1379270:GEMMAAP_RS07715
uniprot id: A0A143BJI5
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1379270:GEMMAAP RS02370
gene id: 1379270:GEMMAAP_RS02370
uniprot id: A0A143BHB0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

1379270:GEMMAAP RS09560
gene id: 1379270:GEMMAAP_RS09560
uniprot id: A0A143BKC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1379270:GEMMAAP RS08935
gene id: 1379270:GEMMAAP_RS08935
uniprot id: A0A143BJY1
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS07425
gene id: 1379270:GEMMAAP_RS07425
uniprot id: A0A143BNI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1379270:GEMMAAP RS08925
gene id: 1379270:GEMMAAP_RS08925
uniprot id: A0A143BK50
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1379270:GEMMAAP RS13030
gene id: 1379270:GEMMAAP_RS13030
uniprot id: A0A143BLZ2
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1379270:GEMMAAP RS00040
gene id: 1379270:GEMMAAP_RS00040
uniprot id: A0A143BP80
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS15025
gene id: 1379270:GEMMAAP_RS15025
uniprot id: A0A143BMK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1379270:GEMMAAP RS05565
gene id: 1379270:GEMMAAP_RS05565
uniprot id: A0A143BIZ1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1379270:GEMMAAP RS07970
gene id: 1379270:GEMMAAP_RS07970
uniprot id: A0A143BJS7
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS19035
gene id: 1379270:GEMMAAP_RS19035
uniprot id: A0A143BMG7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1379270:GEMMAAP RS12865
gene id: 1379270:GEMMAAP_RS12865
uniprot id: A0A143BK46
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

1379270:GEMMAAP RS11350
gene id: 1379270:GEMMAAP_RS11350
uniprot id: A0A143BJI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1379270:GEMMAAP RS14485
gene id: 1379270:GEMMAAP_RS14485
uniprot id: A0A143BKY5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1379270:GEMMAAP RS04165
gene id: 1379270:GEMMAAP_RS04165
uniprot id: A0A143BI10
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1379270:GEMMAAP RS12485
gene id: 1379270:GEMMAAP_RS12485
uniprot id: A0A143BLQ2
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS03500
gene id: 1379270:GEMMAAP_RS03500
uniprot id: A0A143BHR4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1379270:GEMMAAP RS04080
gene id: 1379270:GEMMAAP_RS04080
uniprot id: A0A143BGQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1379270:GEMMAAP RS16320
gene id: 1379270:GEMMAAP_RS16320
uniprot id: A0A143BN31
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1379270:GEMMAAP RS13095
gene id: 1379270:GEMMAAP_RS13095
uniprot id: A0A143BM00
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1379270:GEMMAAP RS00550
gene id: 1379270:GEMMAAP_RS00550
uniprot id: A0A143BGL1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1379270:GEMMAAP RS12015
gene id: 1379270:GEMMAAP_RS12015
uniprot id: A0A143BL44
names: Similarity
messages: Belongs to the PstS family.

1379270:GEMMAAP RS16835
gene id: 1379270:GEMMAAP_RS16835
uniprot id: A0A143BNC2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1379270:GEMMAAP RS06690
gene id: 1379270:GEMMAAP_RS06690
uniprot id: A0A143BJH8
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS18290
gene id: 1379270:GEMMAAP_RS18290
uniprot id: A0A143BNN0
names: Similarity
messages: Belongs to the globin family.

1379270:GEMMAAP RS05235
gene id: 1379270:GEMMAAP_RS05235
uniprot id: A0A143BH70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1379270:GEMMAAP RS19870
gene id: 1379270:GEMMAAP_RS19870
uniprot id: A0A143BPN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1379270:GEMMAAP RS11070
gene id: 1379270:GEMMAAP_RS11070
uniprot id: A0A143BKS7
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1379270:GEMMAAP RS10170
gene id: 1379270:GEMMAAP_RS10170
uniprot id: A0A143BJ50
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

1379270:GEMMAAP RS02425
gene id: 1379270:GEMMAAP_RS02425
uniprot id: A0A143BHK2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1379270:GEMMAAP RS06495
gene id: 1379270:GEMMAAP_RS06495
uniprot id: A0A143BHQ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BchN/ChlN family.
messages: Binds 1 [4Fe-4S] cluster per heterodimer. The cluster is bound at the heterodimer interface by residues from both subunits.
messages: Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.
messages: Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB. Forms a heterotetramer of two BchB and two BchN subunits.

1379270:GEMMAAP RS18300
gene id: 1379270:GEMMAAP_RS18300
uniprot id: A0A143BMB8
names: Similarity
messages: Belongs to the DEAD box helicase family.

1379270:GEMMAAP RS06400
gene id: 1379270:GEMMAAP_RS06400
uniprot id: A0A143BJE2
names: Subcellular Location Annotation
messages: Membrane

1379270:GEMMAAP RS03385
gene id: 1379270:GEMMAAP_RS03385
uniprot id: A0A143BHQ0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1379270:GEMMAAP RS17145
gene id: 1379270:GEMMAAP_RS17145
uniprot id: A0A143BND2
names: Similarity
messages: Belongs to the Skp family.

1379270:GEMMAAP RS11310
gene id: 1379270:GEMMAAP_RS11310
uniprot id: A0A143BL31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1379270:GEMMAAP RS05050
gene id: 1379270:GEMMAAP_RS05050
uniprot id: A0A143BH58
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1379270:GEMMAAP RS12720
gene id: 1379270:GEMMAAP_RS12720
uniprot id: A0A143BK29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1379270:GEMMAAP RS13880
gene id: 1379270:GEMMAAP_RS13880
uniprot id: A0A143BKM7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1379270:GEMMAAP RS12425
gene id: 1379270:GEMMAAP_RS12425
uniprot id: A0A143BLG8
names: Similarity
messages: Belongs to the UbiD family.

1379270:GEMMAAP RS18445
gene id: 1379270:GEMMAAP_RS18445
uniprot id: A0A143BNQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane