1355015:LK06 RS06760
gene id: 1355015:LK06_RS06760
uniprot id: A0A221P8F7
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS04925
gene id: 1355015:LK06_RS04925
uniprot id: A0A221NUP6
names: Similarity
messages: Belongs to the cytochrome P450 family.

1355015:LK06 RS15915
gene id: 1355015:LK06_RS15915
uniprot id: A0A221NZQ9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1355015:LK06 RS07125
gene id: 1355015:LK06_RS07125
uniprot id: A0A221NVI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1355015:LK06 RS20140
gene id: 1355015:LK06_RS20140
uniprot id: A0A221P2V4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1355015:LK06 RS26400
gene id: 1355015:LK06_RS26400
uniprot id: A0A221P9D2
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

1355015:LK06 RS13360
gene id: 1355015:LK06_RS13360
uniprot id: A0A221NYH8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1355015:LK06 RS02375
gene id: 1355015:LK06_RS02375
uniprot id: A0A221NTF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1355015:LK06 RS04220
gene id: 1355015:LK06_RS04220
uniprot id: A0A221P7H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

1355015:LK06 RS05890
gene id: 1355015:LK06_RS05890
uniprot id: A0A221NV47
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1355015:LK06 RS07305
gene id: 1355015:LK06_RS07305
uniprot id: A0A221NW47
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS05110
gene id: 1355015:LK06_RS05110
uniprot id: A0A221NUQ1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS01325
gene id: 1355015:LK06_RS01325
uniprot id: A0A221NTB2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1355015:LK06 RS05045
gene id: 1355015:LK06_RS05045
uniprot id: A0A221NUS1
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1355015:LK06 RS22190
gene id: 1355015:LK06_RS22190
uniprot id: A0A221P2L4
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS27370
gene id: 1355015:LK06_RS27370
uniprot id: A0A221P961
names: Similarity
messages: Belongs to the catalase family.

1355015:LK06 RS24215
gene id: 1355015:LK06_RS24215
uniprot id: A0A221P3G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1355015:LK06 RS29615
gene id: 1355015:LK06_RS29615
uniprot id: A0A221P693
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

1355015:LK06 RS24910
gene id: 1355015:LK06_RS24910
uniprot id: A0A221P3P9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

1355015:LK06 RS21920
gene id: 1355015:LK06_RS21920
uniprot id: A0A221P2K7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.

1355015:LK06 RS10700
gene id: 1355015:LK06_RS10700
uniprot id: A0A221NXP9
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1355015:LK06 RS26600
gene id: 1355015:LK06_RS26600
uniprot id: A0A221P4U0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1355015:LK06 RS02145
gene id: 1355015:LK06_RS02145
uniprot id: A0A221NTT8
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS05895
gene id: 1355015:LK06_RS05895
uniprot id: A0A221NW87
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS13295
gene id: 1355015:LK06_RS13295
uniprot id: A0A221NYH0
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS14570
gene id: 1355015:LK06_RS14570
uniprot id: A0A221NZ23
names: Similarity
messages: Belongs to the cytochrome P450 family.

1355015:LK06 RS24775
gene id: 1355015:LK06_RS24775
uniprot id: A0A221P3N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1355015:LK06 RS20980
gene id: 1355015:LK06_RS20980
uniprot id: A0A221P1Z2
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

1355015:LK06 RS17020
gene id: 1355015:LK06_RS17020
uniprot id: A0A221P047
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1355015:LK06 RS04700
gene id: 1355015:LK06_RS04700
uniprot id: A0A221NUW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1355015:LK06 RS31380
gene id: 1355015:LK06_RS31380
uniprot id: A0A221P9U5
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS19665
gene id: 1355015:LK06_RS19665
uniprot id: A0A221P2L9
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS23350
gene id: 1355015:LK06_RS23350
uniprot id: A0A221P3B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS18775
gene id: 1355015:LK06_RS18775
uniprot id: A0A221P0Z4
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1355015:LK06 RS18615
gene id: 1355015:LK06_RS18615
uniprot id: A0A221P136
names: Similarity
messages: Belongs to the FemABX family.

1355015:LK06 RS15355
gene id: 1355015:LK06_RS15355
uniprot id: A0A221NZN5
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS18110
gene id: 1355015:LK06_RS18110
uniprot id: A0A221P8V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

1355015:LK06 RS22815
gene id: 1355015:LK06_RS22815
uniprot id: A0A221P309
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS24435
gene id: 1355015:LK06_RS24435
uniprot id: A0A221P3P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1355015:LK06 RS06935
gene id: 1355015:LK06_RS06935
uniprot id: A0A221NVL7
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

1355015:LK06 RS04960
gene id: 1355015:LK06_RS04960
uniprot id: A0A221NUN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1355015:LK06 RS21500
gene id: 1355015:LK06_RS21500
uniprot id: A0A221P2F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1355015:LK06 RS01600
gene id: 1355015:LK06_RS01600
uniprot id: A0A221NT23
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1355015:LK06 RS15335
gene id: 1355015:LK06_RS15335
uniprot id: A0A221NZH0
names: Similarity
messages: Belongs to the LOR family.

1355015:LK06 RS20410
gene id: 1355015:LK06_RS20410
uniprot id: A0A221P267
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1355015:LK06 RS08225
gene id: 1355015:LK06_RS08225
uniprot id: A0A221NW61
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1355015:LK06 RS22240
gene id: 1355015:LK06_RS22240
uniprot id: A0A221P2H4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: Nucleus
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1355015:LK06 RS29210
gene id: 1355015:LK06_RS29210
uniprot id: A0A221P5Z9
names: Similarity
messages: Belongs to the thioesterase family.

1355015:LK06 RS10025
gene id: 1355015:LK06_RS10025
uniprot id: A0A221P990
names: Similarity
messages: Belongs to the peptidase S8 family.

1355015:LK06 RS24065
gene id: 1355015:LK06_RS24065
uniprot id: A0A221P3X5
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS11595
gene id: 1355015:LK06_RS11595
uniprot id: A0A221NXY2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1355015:LK06 RS29325
gene id: 1355015:LK06_RS29325
uniprot id: A0A221P5Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

1355015:LK06 RS04690
gene id: 1355015:LK06_RS04690
uniprot id: A0A221NUJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1355015:LK06 RS19070
gene id: 1355015:LK06_RS19070
uniprot id: A0A221P1A1
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1355015:LK06 RS17015
gene id: 1355015:LK06_RS17015
uniprot id: A0A221P0L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1355015:LK06 RS24480
gene id: 1355015:LK06_RS24480
uniprot id: A0A221P3K1
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1355015:LK06 RS05650
gene id: 1355015:LK06_RS05650
uniprot id: A0A221NV43
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

1355015:LK06 RS00315
gene id: 1355015:LK06_RS00315
uniprot id: A0A221NSF2
names: Similarity
messages: Belongs to the peptidase A31 family.

1355015:LK06 RS20160
gene id: 1355015:LK06_RS20160
uniprot id: A0A221P1H7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1355015:LK06 RS21170
gene id: 1355015:LK06_RS21170
uniprot id: A0A221P284
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1355015:LK06 RS12435
gene id: 1355015:LK06_RS12435
uniprot id: A0A221NY57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1355015:LK06 RS20165
gene id: 1355015:LK06_RS20165
uniprot id: A0A221P1M1
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

1355015:LK06 RS29400
gene id: 1355015:LK06_RS29400
uniprot id: A0A221P5V7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1355015:LK06 RS18350
gene id: 1355015:LK06_RS18350
uniprot id: A0A221P0M7
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

1355015:LK06 RS09465
gene id: 1355015:LK06_RS09465
uniprot id: A0A221NWN0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1355015:LK06 RS25180
gene id: 1355015:LK06_RS25180
uniprot id: A0A221P3U1
names: Similarity
messages: Belongs to the IucA/IucC family.

1355015:LK06 RS24220
gene id: 1355015:LK06_RS24220
uniprot id: A0A221P3P7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1355015:LK06 RS29335
gene id: 1355015:LK06_RS29335
uniprot id: A0A221P5U4
names: Similarity
messages: Belongs to the carbamate kinase family.

1355015:LK06 RS04505
gene id: 1355015:LK06_RS04505
uniprot id: A0A221NUD8
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1355015:LK06 RS21245
gene id: 1355015:LK06_RS21245
uniprot id: A0A221P2A9
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

1355015:LK06 RS23310
gene id: 1355015:LK06_RS23310
uniprot id: A0A221P3I2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1355015:LK06 RS23345
gene id: 1355015:LK06_RS23345
uniprot id: A0A221P2Y5
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1355015:LK06 RS01540
gene id: 1355015:LK06_RS01540
uniprot id: A0A221NSZ3
names: Function
messages: Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

1355015:LK06 RS08140
gene id: 1355015:LK06_RS08140
uniprot id: A0A221NW10
names: Similarity
messages: Belongs to the glutamine synthetase family.

1355015:LK06 RS25520
gene id: 1355015:LK06_RS25520
uniprot id: A0A221P4M9
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS11645
gene id: 1355015:LK06_RS11645
uniprot id: A0A221NXZ2
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1355015:LK06 RS16260
gene id: 1355015:LK06_RS16260
uniprot id: A0A221NZW4
names: Similarity
messages: Belongs to the SCO1/2 family.

1355015:LK06 RS02370
gene id: 1355015:LK06_RS02370
uniprot id: A0A221NTE1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1355015:LK06 RS11940
gene id: 1355015:LK06_RS11940
uniprot id: A0A221P8G9
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1355015:LK06 RS08450
gene id: 1355015:LK06_RS08450
uniprot id: A0A221NWF0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1355015:LK06 RS13590
gene id: 1355015:LK06_RS13590
uniprot id: A0A221P9I8
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1355015:LK06 RS07410
gene id: 1355015:LK06_RS07410
uniprot id: A0A221NX01
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS23505
gene id: 1355015:LK06_RS23505
uniprot id: A0A221P3B3
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1355015:LK06 RS24780
gene id: 1355015:LK06_RS24780
uniprot id: A0A221P432
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1355015:LK06 RS27590
gene id: 1355015:LK06_RS27590
uniprot id: A0A221P5B6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1355015:LK06 RS04885
gene id: 1355015:LK06_RS04885
uniprot id: A0A221NUJ8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1355015:LK06 RS28850
gene id: 1355015:LK06_RS28850
uniprot id: A0A221P5R1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1355015:LK06 RS01115
gene id: 1355015:LK06_RS01115
uniprot id: A0A221NST0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1355015:LK06 RS30730
gene id: 1355015:LK06_RS30730
uniprot id: A0A221P6F7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1355015:LK06 RS14755
gene id: 1355015:LK06_RS14755
uniprot id: A0A221P0G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1355015:LK06 RS16070
gene id: 1355015:LK06_RS16070
uniprot id: A0A221NZN8
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1355015:LK06 RS23970
gene id: 1355015:LK06_RS23970
uniprot id: A0A221P3G2
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1355015:LK06 RS23295
gene id: 1355015:LK06_RS23295
uniprot id: A0A221P2X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1355015:LK06 RS12315
gene id: 1355015:LK06_RS12315
uniprot id: A0A221NY33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1355015:LK06 RS26540
gene id: 1355015:LK06_RS26540
uniprot id: A0A221P4S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1355015:LK06 RS25125
gene id: 1355015:LK06_RS25125
uniprot id: A0A221P3T0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1355015:LK06 RS16060
gene id: 1355015:LK06_RS16060
uniprot id: A0A221NZP8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1355015:LK06 RS28735
gene id: 1355015:LK06_RS28735
uniprot id: A0A221P6W6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1355015:LK06 RS20210
gene id: 1355015:LK06_RS20210
uniprot id: A0A221P220
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1355015:LK06 RS02330
gene id: 1355015:LK06_RS02330
uniprot id: A0A221NTK4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS16635
gene id: 1355015:LK06_RS16635
uniprot id: A0A221NZY0
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS29330
gene id: 1355015:LK06_RS29330
uniprot id: A0A221P6J9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS19090
gene id: 1355015:LK06_RS19090
uniprot id: A0A221P2D6
names: Subcellular Location Annotation
messages: Cell membrane

1355015:LK06 RS13100
gene id: 1355015:LK06_RS13100
uniprot id: A0A221NZQ3
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS22435
gene id: 1355015:LK06_RS22435
uniprot id: A0A221P368
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1355015:LK06 RS18685
gene id: 1355015:LK06_RS18685
uniprot id: A0A221P0W7
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1355015:LK06 RS21820
gene id: 1355015:LK06_RS21820
uniprot id: A0A221P2L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS05205
gene id: 1355015:LK06_RS05205
uniprot id: A0A221NUN2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

1355015:LK06 RS12420
gene id: 1355015:LK06_RS12420
uniprot id: A0A221NZF0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1355015:LK06 RS05365
gene id: 1355015:LK06_RS05365
uniprot id: A0A221NVA8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1355015:LK06 RS29440
gene id: 1355015:LK06_RS29440
uniprot id: A0A221P5W4
names: Similarity
messages: Belongs to the cytochrome P450 family.

1355015:LK06 RS14505
gene id: 1355015:LK06_RS14505
uniprot id: A0A221NZ89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1355015:LK06 RS08295
gene id: 1355015:LK06_RS08295
uniprot id: A0A221NW75
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

1355015:LK06 RS04665
gene id: 1355015:LK06_RS04665
uniprot id: A0A221NUN1
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS25195
gene id: 1355015:LK06_RS25195
uniprot id: A0A221P572
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1355015:LK06 RS26970
gene id: 1355015:LK06_RS26970
uniprot id: A0A221P4Q8
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

1355015:LK06 RS03845
gene id: 1355015:LK06_RS03845
uniprot id: A0A221NVA7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

1355015:LK06 RS22690
gene id: 1355015:LK06_RS22690
uniprot id: A0A221P2P8
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1355015:LK06 RS00100
gene id: 1355015:LK06_RS00100
uniprot id: A0A221NSB1
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS05570
gene id: 1355015:LK06_RS05570
uniprot id: A0A221NUW5
names: Similarity
messages: Belongs to the peptidase S1 family.

1355015:LK06 RS21275
gene id: 1355015:LK06_RS21275
uniprot id: A0A221P224
names: Similarity
messages: Belongs to the GSP E family.

1355015:LK06 RS11005
gene id: 1355015:LK06_RS11005
uniprot id: A0A221NXL1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1355015:LK06 RS24420
gene id: 1355015:LK06_RS24420
uniprot id: A0A221P3P0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1355015:LK06 RS19615
gene id: 1355015:LK06_RS19615
uniprot id: A0A221P1I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

1355015:LK06 RS16065
gene id: 1355015:LK06_RS16065
uniprot id: A0A221P0B5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1355015:LK06 RS12935
gene id: 1355015:LK06_RS12935
uniprot id: A0A221NYD9
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.

1355015:LK06 RS11040
gene id: 1355015:LK06_RS11040
uniprot id: A0A221NXD7
names: Similarity
messages: Belongs to the UPF0303 family.

1355015:LK06 RS12385
gene id: 1355015:LK06_RS12385
uniprot id: A0A221NY60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS10605
gene id: 1355015:LK06_RS10605
uniprot id: A0A221P8P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1355015:LK06 RS08000
gene id: 1355015:LK06_RS08000
uniprot id: A0A221NVY6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS13840
gene id: 1355015:LK06_RS13840
uniprot id: A0A221NYL9
names: Similarity
messages: Belongs to the UPF0145 family.

1355015:LK06 RS18715
gene id: 1355015:LK06_RS18715
uniprot id: A0A221P0Y0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1355015:LK06 RS25445
gene id: 1355015:LK06_RS25445
uniprot id: A0A221P3X8
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1355015:LK06 RS12885
gene id: 1355015:LK06_RS12885
uniprot id: A0A221NYC9
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1355015:LK06 RS05990
gene id: 1355015:LK06_RS05990
uniprot id: A0A221NUZ9
names: Similarity
messages: Belongs to the peptidase U62 family.

1355015:LK06 RS07300
gene id: 1355015:LK06_RS07300
uniprot id: A0A221NWY2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS22405
gene id: 1355015:LK06_RS22405
uniprot id: A0A221P2W3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1355015:LK06 RS19140
gene id: 1355015:LK06_RS19140
uniprot id: A0A221P1C1
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS13795
gene id: 1355015:LK06_RS13795
uniprot id: A0A221P002
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1355015:LK06 RS06280
gene id: 1355015:LK06_RS06280
uniprot id: A0A221NVD8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1355015:LK06 RS06540
gene id: 1355015:LK06_RS06540
uniprot id: A0A221NVU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1355015:LK06 RS28620
gene id: 1355015:LK06_RS28620
uniprot id: A0A221P5V8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1355015:LK06 RS12155
gene id: 1355015:LK06_RS12155
uniprot id: A0A221NYF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1355015:LK06 RS29955
gene id: 1355015:LK06_RS29955
uniprot id: A0A221P684
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1355015:LK06 RS00250
gene id: 1355015:LK06_RS00250
uniprot id: A0A221NSE6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1355015:LK06 RS25660
gene id: 1355015:LK06_RS25660
uniprot id: A0A221P444
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1355015:LK06 RS20690
gene id: 1355015:LK06_RS20690
uniprot id: A0A221P2A2
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS21375
gene id: 1355015:LK06_RS21375
uniprot id: A0A221P235
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1355015:LK06 RS24570
gene id: 1355015:LK06_RS24570
uniprot id: A0A221P3S4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1355015:LK06 RS28675
gene id: 1355015:LK06_RS28675
uniprot id: A0A221P5W6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

1355015:LK06 RS17500
gene id: 1355015:LK06_RS17500
uniprot id: A0A221P1N0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1355015:LK06 RS08655
gene id: 1355015:LK06_RS08655
uniprot id: A0A221NWJ9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1355015:LK06 RS20400
gene id: 1355015:LK06_RS20400
uniprot id: A0A221P251
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS17875
gene id: 1355015:LK06_RS17875
uniprot id: A0A221P129
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS04195
gene id: 1355015:LK06_RS04195
uniprot id: A0A221NUP2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1355015:LK06 RS03840
gene id: 1355015:LK06_RS03840
uniprot id: A0A221NU59
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS14095
gene id: 1355015:LK06_RS14095
uniprot id: A0A221NYS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1355015:LK06 RS31780
gene id: 1355015:LK06_RS31780
uniprot id: A0A221P7M3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1355015:LK06 RS30250
gene id: 1355015:LK06_RS30250
uniprot id: A0A221P922
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS04100
gene id: 1355015:LK06_RS04100
uniprot id: A0A221NU94
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1355015:LK06 RS21970
gene id: 1355015:LK06_RS21970
uniprot id: A0A221P2F6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1355015:LK06 RS26225
gene id: 1355015:LK06_RS26225
uniprot id: A0A221P4B0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1355015:LK06 RS03660
gene id: 1355015:LK06_RS03660
uniprot id: A0A221NV80
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1355015:LK06 RS18555
gene id: 1355015:LK06_RS18555
uniprot id: A0A221P127
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1355015:LK06 RS24655
gene id: 1355015:LK06_RS24655
uniprot id: A0A221P3P2
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

1355015:LK06 RS11630
gene id: 1355015:LK06_RS11630
uniprot id: A0A221NXN8
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1355015:LK06 RS08610
gene id: 1355015:LK06_RS08610
uniprot id: A0A221NW89
names: Similarity
messages: Belongs to the cytochrome P450 family.

1355015:LK06 RS19300
gene id: 1355015:LK06_RS19300
uniprot id: A0A221P1C8
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS28665
gene id: 1355015:LK06_RS28665
uniprot id: A0A221P5S9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1355015:LK06 RS09390
gene id: 1355015:LK06_RS09390
uniprot id: A0A221NWS9
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1355015:LK06 RS30000
gene id: 1355015:LK06_RS30000
uniprot id: A0A221P9H4
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1355015:LK06 RS02205
gene id: 1355015:LK06_RS02205
uniprot id: A0A221NTC6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

1355015:LK06 RS23750
gene id: 1355015:LK06_RS23750
uniprot id: A0A221P3F5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1355015:LK06 RS05785
gene id: 1355015:LK06_RS05785
uniprot id: A0A221NV39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1355015:LK06 RS22720
gene id: 1355015:LK06_RS22720
uniprot id: A0A221P313
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1355015:LK06 RS20155
gene id: 1355015:LK06_RS20155
uniprot id: A0A221P232
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1355015:LK06 RS07535
gene id: 1355015:LK06_RS07535
uniprot id: A0A221NVT7
names: Similarity
messages: Belongs to the arsA ATPase family.

1355015:LK06 RS04570
gene id: 1355015:LK06_RS04570
uniprot id: A0A221NVM8
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1355015:LK06 RS01475
gene id: 1355015:LK06_RS01475
uniprot id: A0A221P7D2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1355015:LK06 RS22425
gene id: 1355015:LK06_RS22425
uniprot id: A0A221P2S2
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1355015:LK06 RS29835
gene id: 1355015:LK06_RS29835
uniprot id: A0A221P692
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1355015:LK06 RS08410
gene id: 1355015:LK06_RS08410
uniprot id: A0A221NWM9
names: Similarity
messages: Belongs to the UPF0246 family.

1355015:LK06 RS26130
gene id: 1355015:LK06_RS26130
uniprot id: A0A221P4Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1355015:LK06 RS11275
gene id: 1355015:LK06_RS11275
uniprot id: A0A221NXJ4
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS20620
gene id: 1355015:LK06_RS20620
uniprot id: A0A221P207
names: Similarity
names: Subunit
messages: Belongs to the CMP-NeuNAc synthase family.
messages: Belongs to the KdsC family.
messages: Homotetramer.

1355015:LK06 RS12640
gene id: 1355015:LK06_RS12640
uniprot id: A0A221NY87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1355015:LK06 RS01875
gene id: 1355015:LK06_RS01875
uniprot id: A0A221NT66
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1355015:LK06 RS20995
gene id: 1355015:LK06_RS20995
uniprot id: A0A221P269
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1355015:LK06 RS17460
gene id: 1355015:LK06_RS17460
uniprot id: A0A221P085
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1355015:LK06 RS22820
gene id: 1355015:LK06_RS22820
uniprot id: A0A221P2Q7
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS18870
gene id: 1355015:LK06_RS18870
uniprot id: A0A221P0X0
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS20120
gene id: 1355015:LK06_RS20120
uniprot id: A0A221P1K6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1355015:LK06 RS04820
gene id: 1355015:LK06_RS04820
uniprot id: A0A221NUI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1355015:LK06 RS07565
gene id: 1355015:LK06_RS07565
uniprot id: A0A221NVZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1355015:LK06 RS24005
gene id: 1355015:LK06_RS24005
uniprot id: A0A221P3U2
names: Cofactor
messages: Binds 1 FAD per subunit.

1355015:LK06 RS22680
gene id: 1355015:LK06_RS22680
uniprot id: A0A221P2V9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S16 family.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1355015:LK06 RS28435
gene id: 1355015:LK06_RS28435
uniprot id: A0A221P5T2
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1355015:LK06 RS06905
gene id: 1355015:LK06_RS06905
uniprot id: A0A221NVX6
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS23235
gene id: 1355015:LK06_RS23235
uniprot id: A0A221P8W5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1355015:LK06 RS02295
gene id: 1355015:LK06_RS02295
uniprot id: A0A221NUM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1355015:LK06 RS27820
gene id: 1355015:LK06_RS27820
uniprot id: A0A221P5F6
names: Similarity
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Homohexamer. The oligomerization is ATP-dependent.

1355015:LK06 RS29245
gene id: 1355015:LK06_RS29245
uniprot id: A0A221P755
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1355015:LK06 RS11960
gene id: 1355015:LK06_RS11960
uniprot id: A0A221NXU1
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1355015:LK06 RS27815
gene id: 1355015:LK06_RS27815
uniprot id: A0A221P548
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1355015:LK06 RS27985
gene id: 1355015:LK06_RS27985
uniprot id: A0A221P5B7
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1355015:LK06 RS19605
gene id: 1355015:LK06_RS19605
uniprot id: A0A221P2K8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1355015:LK06 RS01335
gene id: 1355015:LK06_RS01335
uniprot id: A0A221NTF0
names: Similarity
messages: Belongs to the pirin family.

1355015:LK06 RS05925
gene id: 1355015:LK06_RS05925
uniprot id: A0A221NV19
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1355015:LK06 RS17040
gene id: 1355015:LK06_RS17040
uniprot id: A0A221P080
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1355015:LK06 RS20870
gene id: 1355015:LK06_RS20870
uniprot id: A0A221P380
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

1355015:LK06 RS11075
gene id: 1355015:LK06_RS11075
uniprot id: A0A221NXW1
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS08960
gene id: 1355015:LK06_RS08960
uniprot id: A0A221NXU6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS15290
gene id: 1355015:LK06_RS15290
uniprot id: A0A221NZA0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1355015:LK06 RS30750
gene id: 1355015:LK06_RS30750
uniprot id: A0A221P7S9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1355015:LK06 RS24470
gene id: 1355015:LK06_RS24470
uniprot id: A0A221P3Q1
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1355015:LK06 RS10725
gene id: 1355015:LK06_RS10725
uniprot id: A0A221NXD9
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1355015:LK06 RS23575
gene id: 1355015:LK06_RS23575
uniprot id: A0A221P3F7
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS09975
gene id: 1355015:LK06_RS09975
uniprot id: A0A221NWW1
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1355015:LK06 RS18605
gene id: 1355015:LK06_RS18605
uniprot id: A0A221P130
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS12410
gene id: 1355015:LK06_RS12410
uniprot id: A0A221NXZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1355015:LK06 RS11565
gene id: 1355015:LK06_RS11565
uniprot id: A0A221NXP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1355015:LK06 RS01435
gene id: 1355015:LK06_RS01435
uniprot id: A0A221NT21
names: Subcellular Location Annotation
messages: Cell membrane

1355015:LK06 RS29680
gene id: 1355015:LK06_RS29680
uniprot id: A0A221P6A3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

1355015:LK06 RS17530
gene id: 1355015:LK06_RS17530
uniprot id: A0A221P0E9
names: Similarity
messages: Belongs to the CsoR family.

1355015:LK06 RS21480
gene id: 1355015:LK06_RS21480
uniprot id: A0A221P2A3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1355015:LK06 RS04150
gene id: 1355015:LK06_RS04150
uniprot id: A0A221NU66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1355015:LK06 RS18265
gene id: 1355015:LK06_RS18265
uniprot id: A0A221P1Z7
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

1355015:LK06 RS04165
gene id: 1355015:LK06_RS04165
uniprot id: A0A221NUE5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS19265
gene id: 1355015:LK06_RS19265
uniprot id: A0A221P1C9
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS03085
gene id: 1355015:LK06_RS03085
uniprot id: A0A221NTT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS16955
gene id: 1355015:LK06_RS16955
uniprot id: A0A221P019
names: Similarity
messages: Belongs to the GARS family.

1355015:LK06 RS13520
gene id: 1355015:LK06_RS13520
uniprot id: A0A221P7X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1355015:LK06 RS24890
gene id: 1355015:LK06_RS24890
uniprot id: A0A221P3R5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1355015:LK06 RS31110
gene id: 1355015:LK06_RS31110
uniprot id: A0A221P6L8
names: Similarity
messages: Belongs to the fructosamine kinase family.

1355015:LK06 RS31465
gene id: 1355015:LK06_RS31465
uniprot id: A0A221P6R1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS00300
gene id: 1355015:LK06_RS00300
uniprot id: A0A221NSE3
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1355015:LK06 RS01070
gene id: 1355015:LK06_RS01070
uniprot id: A0A221NSX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I16 (SSI) family.
messages: Homodimer.
messages: Secreted
messages: Strong inhibitor of bacterial serine proteases such as subtilisin.

1355015:LK06 RS11710
gene id: 1355015:LK06_RS11710
uniprot id: A0A221NY01
names: Similarity
messages: Belongs to the peptidase C56 family.

1355015:LK06 RS23680
gene id: 1355015:LK06_RS23680
uniprot id: A0A221P3B8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1355015:LK06 RS07795
gene id: 1355015:LK06_RS07795
uniprot id: A0A221NW40
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1355015:LK06 RS25065
gene id: 1355015:LK06_RS25065
uniprot id: A0A221P472
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS21870
gene id: 1355015:LK06_RS21870
uniprot id: A0A221P2J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS09270
gene id: 1355015:LK06_RS09270
uniprot id: A0A221NWN5
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1355015:LK06 RS25975
gene id: 1355015:LK06_RS25975
uniprot id: A0A221P470
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1355015:LK06 RS07660
gene id: 1355015:LK06_RS07660
uniprot id: A0A221NVT3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Belongs to the sulfur carrier protein TusA family.

1355015:LK06 RS04930
gene id: 1355015:LK06_RS04930
uniprot id: A0A221NVT9
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1355015:LK06 RS00255
gene id: 1355015:LK06_RS00255
uniprot id: A0A221NSE1
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1355015:LK06 RS18545
gene id: 1355015:LK06_RS18545
uniprot id: A0A221P119
names: Subcellular Location Annotation
messages: Cell membrane

1355015:LK06 RS12370
gene id: 1355015:LK06_RS12370
uniprot id: A0A221NY48
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1355015:LK06 RS06885
gene id: 1355015:LK06_RS06885
uniprot id: A0A221NVE1
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1355015:LK06 RS28590
gene id: 1355015:LK06_RS28590
uniprot id: A0A221P5N7
names: Similarity
messages: Belongs to the YciI family.

1355015:LK06 RS28760
gene id: 1355015:LK06_RS28760
uniprot id: A0A221P5R8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1355015:LK06 RS04145
gene id: 1355015:LK06_RS04145
uniprot id: A0A221NUR3
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1355015:LK06 RS18790
gene id: 1355015:LK06_RS18790
uniprot id: A0A221P161
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1355015:LK06 RS26765
gene id: 1355015:LK06_RS26765
uniprot id: A0A221P4X1
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1355015:LK06 RS13365
gene id: 1355015:LK06_RS13365
uniprot id: A0A221NZ11
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1355015:LK06 RS03940
gene id: 1355015:LK06_RS03940
uniprot id: A0A221NU65
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1355015:LK06 RS11910
gene id: 1355015:LK06_RS11910
uniprot id: A0A221NY30
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofD family.
messages: Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS02170
gene id: 1355015:LK06_RS02170
uniprot id: A0A221NT95
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1355015:LK06 RS16135
gene id: 1355015:LK06_RS16135
uniprot id: A0A221P0C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1355015:LK06 RS15825
gene id: 1355015:LK06_RS15825
uniprot id: A0A221NZJ2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1355015:LK06 RS01720
gene id: 1355015:LK06_RS01720
uniprot id: A0A221NT97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1355015:LK06 RS21205
gene id: 1355015:LK06_RS21205
uniprot id: A0A221P211
names: Similarity
messages: Belongs to the DSD1 family.

1355015:LK06 RS15115
gene id: 1355015:LK06_RS15115
uniprot id: A0A221NZD3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1355015:LK06 RS25265
gene id: 1355015:LK06_RS25265
uniprot id: A0A221P4G5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1355015:LK06 RS19340
gene id: 1355015:LK06_RS19340
uniprot id: A0A221P145
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase involved in purine salvage.

1355015:LK06 RS12450
gene id: 1355015:LK06_RS12450
uniprot id: A0A221NY70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1355015:LK06 RS15995
gene id: 1355015:LK06_RS15995
uniprot id: A0A221P072
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS29645
gene id: 1355015:LK06_RS29645
uniprot id: A0A221P979
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1355015:LK06 RS26755
gene id: 1355015:LK06_RS26755
uniprot id: A0A221P4S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1355015:LK06 RS12440
gene id: 1355015:LK06_RS12440
uniprot id: A0A221NYM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1355015:LK06 RS25910
gene id: 1355015:LK06_RS25910
uniprot id: A0A221P4D0
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS32075
gene id: 1355015:LK06_RS32075
uniprot id: A0A221P757
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1355015:LK06 RS14340
gene id: 1355015:LK06_RS14340
uniprot id: A0A221P090
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS07265
gene id: 1355015:LK06_RS07265
uniprot id: A0A221NVK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

1355015:LK06 RS01680
gene id: 1355015:LK06_RS01680
uniprot id: A0A221NUA8
names: Similarity
messages: Belongs to the FPG family.

1355015:LK06 RS11680
gene id: 1355015:LK06_RS11680
uniprot id: A0A221NY84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS26990
gene id: 1355015:LK06_RS26990
uniprot id: A0A221P4N4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1355015:LK06 RS26825
gene id: 1355015:LK06_RS26825
uniprot id: A0A221P4K5
names: Similarity
messages: Belongs to the terpene synthase family.

1355015:LK06 RS23440
gene id: 1355015:LK06_RS23440
uniprot id: A0A221P331
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1355015:LK06 RS31675
gene id: 1355015:LK06_RS31675
uniprot id: A0A221P6V9
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1355015:LK06 RS12205
gene id: 1355015:LK06_RS12205
uniprot id: A0A221NYG7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1355015:LK06 RS21005
gene id: 1355015:LK06_RS21005
uniprot id: A0A221P2F0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

1355015:LK06 RS17505
gene id: 1355015:LK06_RS17505
uniprot id: A0A221P0T1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1355015:LK06 RS12175
gene id: 1355015:LK06_RS12175
uniprot id: A0A221NY15
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1355015:LK06 RS27545
gene id: 1355015:LK06_RS27545
uniprot id: A0A221P8V5
names: Similarity
messages: Belongs to the allantoicase family.

1355015:LK06 RS17795
gene id: 1355015:LK06_RS17795
uniprot id: A0A221P0R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

1355015:LK06 RS05385
gene id: 1355015:LK06_RS05385
uniprot id: A0A221NV01
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the homogentisate dioxygenase family.
messages: Hexamer; dimer of trimers.
messages: Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS18240
gene id: 1355015:LK06_RS18240
uniprot id: A0A221P0X4
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1355015:LK06 RS12890
gene id: 1355015:LK06_RS12890
uniprot id: A0A221NYB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1355015:LK06 RS04795
gene id: 1355015:LK06_RS04795
uniprot id: A0A221NUQ0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1355015:LK06 RS02320
gene id: 1355015:LK06_RS02320
uniprot id: A0A221NTE7
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1355015:LK06 RS27860
gene id: 1355015:LK06_RS27860
uniprot id: A0A221P564
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

1355015:LK06 RS19980
gene id: 1355015:LK06_RS19980
uniprot id: A0A221P205
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1355015:LK06 RS00790
gene id: 1355015:LK06_RS00790
uniprot id: A0A221NSJ3
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1355015:LK06 RS19285
gene id: 1355015:LK06_RS19285
uniprot id: A0A221P2G2
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1355015:LK06 RS20540
gene id: 1355015:LK06_RS20540
uniprot id: A0A221P294
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1355015:LK06 RS14615
gene id: 1355015:LK06_RS14615
uniprot id: A0A221NZA8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS15935
gene id: 1355015:LK06_RS15935
uniprot id: A0A221NZY6
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS24510
gene id: 1355015:LK06_RS24510
uniprot id: A0A221P4W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1355015:LK06 RS04985
gene id: 1355015:LK06_RS04985
uniprot id: A0A221NUQ9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1355015:LK06 RS15575
gene id: 1355015:LK06_RS15575
uniprot id: A0A221NZF3
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS20825
gene id: 1355015:LK06_RS20825
uniprot id: A0A221P223
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1355015:LK06 RS07910
gene id: 1355015:LK06_RS07910
uniprot id: A0A221NW06
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1355015:LK06 RS04105
gene id: 1355015:LK06_RS04105
uniprot id: A0A221NU83
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1355015:LK06 RS13715
gene id: 1355015:LK06_RS13715
uniprot id: A0A221P897
names: Similarity
messages: Belongs to the threonine aldolase family.

1355015:LK06 RS19750
gene id: 1355015:LK06_RS19750
uniprot id: A0A221P1E5
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1355015:LK06 RS02490
gene id: 1355015:LK06_RS02490
uniprot id: A0A221NTH2
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1355015:LK06 RS07525
gene id: 1355015:LK06_RS07525
uniprot id: A0A221NX22
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1355015:LK06 RS09380
gene id: 1355015:LK06_RS09380
uniprot id: A0A221P968
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

1355015:LK06 RS23220
gene id: 1355015:LK06_RS23220
uniprot id: A0A221P366
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1355015:LK06 RS07740
gene id: 1355015:LK06_RS07740
uniprot id: A0A221NVT5
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1355015:LK06 RS10445
gene id: 1355015:LK06_RS10445
uniprot id: A0A221NX48
names: Similarity
messages: Belongs to the TPP enzyme family.

1355015:LK06 RS28025
gene id: 1355015:LK06_RS28025
uniprot id: A0A221P555
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS25325
gene id: 1355015:LK06_RS25325
uniprot id: A0A221P4H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1355015:LK06 RS08245
gene id: 1355015:LK06_RS08245
uniprot id: A0A221NW62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS19930
gene id: 1355015:LK06_RS19930
uniprot id: A0A221P1Z5
names: Similarity
messages: Belongs to the cytochrome P450 family.

1355015:LK06 RS09575
gene id: 1355015:LK06_RS09575
uniprot id: A0A221NWP9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS04630
gene id: 1355015:LK06_RS04630
uniprot id: A0A221NUW1
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS12165
gene id: 1355015:LK06_RS12165
uniprot id: A0A221NYG6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS30835
gene id: 1355015:LK06_RS30835
uniprot id: A0A221P6N2
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS25490
gene id: 1355015:LK06_RS25490
uniprot id: A0A221P4A8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1355015:LK06 RS11515
gene id: 1355015:LK06_RS11515
uniprot id: A0A221NXM1
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1355015:LK06 RS08275
gene id: 1355015:LK06_RS08275
uniprot id: A0A221NW74
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1355015:LK06 RS04230
gene id: 1355015:LK06_RS04230
uniprot id: A0A221NUB6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1355015:LK06 RS13920
gene id: 1355015:LK06_RS13920
uniprot id: A0A221P8L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS23885
gene id: 1355015:LK06_RS23885
uniprot id: A0A221P3K8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1355015:LK06 RS26700
gene id: 1355015:LK06_RS26700
uniprot id: A0A221P4L0
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Reversible hydration of carbon dioxide.

1355015:LK06 RS31270
gene id: 1355015:LK06_RS31270
uniprot id: A0A221P6V5
names: Similarity
messages: Belongs to the HupF/HypC family.

1355015:LK06 RS01545
gene id: 1355015:LK06_RS01545
uniprot id: A0A221NT09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. EgtD family.
messages: Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine.
messages: Monomer.

1355015:LK06 RS13695
gene id: 1355015:LK06_RS13695
uniprot id: A0A221NZ56
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1355015:LK06 RS23305
gene id: 1355015:LK06_RS23305
uniprot id: A0A221P4B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1355015:LK06 RS11455
gene id: 1355015:LK06_RS11455
uniprot id: A0A221NY42
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1355015:LK06 RS18960
gene id: 1355015:LK06_RS18960
uniprot id: A0A221P0X9
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1355015:LK06 RS26535
gene id: 1355015:LK06_RS26535
uniprot id: A0A221P4I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1355015:LK06 RS21760
gene id: 1355015:LK06_RS21760
uniprot id: A0A221P2J3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1355015:LK06 RS24235
gene id: 1355015:LK06_RS24235
uniprot id: A0A221P4R5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1355015:LK06 RS24185
gene id: 1355015:LK06_RS24185
uniprot id: A0A221P4Q4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1355015:LK06 RS06235
gene id: 1355015:LK06_RS06235
uniprot id: A0A221NVM2
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1355015:LK06 RS09610
gene id: 1355015:LK06_RS09610
uniprot id: A0A221NWY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1355015:LK06 RS06640
gene id: 1355015:LK06_RS06640
uniprot id: A0A221NVE4
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1355015:LK06 RS07290
gene id: 1355015:LK06_RS07290
uniprot id: A0A221NVV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1355015:LK06 RS00220
gene id: 1355015:LK06_RS00220
uniprot id: A0A221NTL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane

1355015:LK06 RS11750
gene id: 1355015:LK06_RS11750
uniprot id: A0A221NY94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1355015:LK06 RS09515
gene id: 1355015:LK06_RS09515
uniprot id: A0A221P8L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1355015:LK06 RS19825
gene id: 1355015:LK06_RS19825
uniprot id: A0A221P1N6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1355015:LK06 RS15870
gene id: 1355015:LK06_RS15870
uniprot id: A0A221NZX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1355015:LK06 RS00875
gene id: 1355015:LK06_RS00875
uniprot id: A0A221NT35
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS05720
gene id: 1355015:LK06_RS05720
uniprot id: A0A221NV27
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS01920
gene id: 1355015:LK06_RS01920
uniprot id: A0A221NTQ1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1355015:LK06 RS22730
gene id: 1355015:LK06_RS22730
uniprot id: A0A221P3A0
names: Similarity
messages: Belongs to the peptidase C40 family.

1355015:LK06 RS23215
gene id: 1355015:LK06_RS23215
uniprot id: A0A221P2Z9
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1355015:LK06 RS09865
gene id: 1355015:LK06_RS09865
uniprot id: A0A221NWT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1355015:LK06 RS02840
gene id: 1355015:LK06_RS02840
uniprot id: A0A221NTP6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1355015:LK06 RS16950
gene id: 1355015:LK06_RS16950
uniprot id: A0A221P0P6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1355015:LK06 RS20145
gene id: 1355015:LK06_RS20145
uniprot id: A0A221P212
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1355015:LK06 RS10975
gene id: 1355015:LK06_RS10975
uniprot id: A0A221NXC8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

1355015:LK06 RS08115
gene id: 1355015:LK06_RS08115
uniprot id: A0A221NW08
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

1355015:LK06 RS04070
gene id: 1355015:LK06_RS04070
uniprot id: A0A221NU98
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS07105
gene id: 1355015:LK06_RS07105
uniprot id: A0A221NVP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1355015:LK06 RS20485
gene id: 1355015:LK06_RS20485
uniprot id: A0A221P278
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS07630
gene id: 1355015:LK06_RS07630
uniprot id: A0A221NVR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS04585
gene id: 1355015:LK06_RS04585
uniprot id: A0A221NUX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1355015:LK06 RS31835
gene id: 1355015:LK06_RS31835
uniprot id: A0A221P9N2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1355015:LK06 RS26930
gene id: 1355015:LK06_RS26930
uniprot id: A0A221P4Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1355015:LK06 RS05210
gene id: 1355015:LK06_RS05210
uniprot id: A0A221NUU7
names: Similarity
messages: Belongs to the CapA family.

1355015:LK06 RS05605
gene id: 1355015:LK06_RS05605
uniprot id: A0A221NV08
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1355015:LK06 RS19645
gene id: 1355015:LK06_RS19645
uniprot id: A0A221P1C5
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1355015:LK06 RS21260
gene id: 1355015:LK06_RS21260
uniprot id: A0A221P290
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS12980
gene id: 1355015:LK06_RS12980
uniprot id: A0A221NYT6
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1355015:LK06 RS04125
gene id: 1355015:LK06_RS04125
uniprot id: A0A221NVF9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS20355
gene id: 1355015:LK06_RS20355
uniprot id: A0A221P258
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1355015:LK06 RS08555
gene id: 1355015:LK06_RS08555
uniprot id: A0A221NW80
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1355015:LK06 RS17520
gene id: 1355015:LK06_RS17520
uniprot id: A0A221P099
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS11775
gene id: 1355015:LK06_RS11775
uniprot id: A0A221NXS2
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1355015:LK06 RS24700
gene id: 1355015:LK06_RS24700
uniprot id: A0A221P495
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS05025
gene id: 1355015:LK06_RS05025
uniprot id: A0A221NUM8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

1355015:LK06 RS09585
gene id: 1355015:LK06_RS09585
uniprot id: A0A221NWT2
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1355015:LK06 RS27380
gene id: 1355015:LK06_RS27380
uniprot id: A0A221P5M0
names: Similarity
messages: Belongs to the hyi family.

1355015:LK06 RS12085
gene id: 1355015:LK06_RS12085
uniprot id: A0A221NY41
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1355015:LK06 RS24500
gene id: 1355015:LK06_RS24500
uniprot id: A0A221P3I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1355015:LK06 RS24040
gene id: 1355015:LK06_RS24040
uniprot id: A0A221P3A1
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: May form a heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits. May also form a heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1355015:LK06 RS07610
gene id: 1355015:LK06_RS07610
uniprot id: A0A221NVS0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS28305
gene id: 1355015:LK06_RS28305
uniprot id: A0A221P629
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1355015:LK06 RS06435
gene id: 1355015:LK06_RS06435
uniprot id: A0A221NVD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

1355015:LK06 RS13480
gene id: 1355015:LK06_RS13480
uniprot id: A0A221NZ13
names: Similarity
messages: Belongs to the histone deacetylase family.

1355015:LK06 RS20130
gene id: 1355015:LK06_RS20130
uniprot id: A0A221P1G4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1355015:LK06 RS15440
gene id: 1355015:LK06_RS15440
uniprot id: A0A221NZD7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1355015:LK06 RS04330
gene id: 1355015:LK06_RS04330
uniprot id: A0A221NU96
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1355015:LK06 RS22580
gene id: 1355015:LK06_RS22580
uniprot id: A0A221P2S5
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1355015:LK06 RS23370
gene id: 1355015:LK06_RS23370
uniprot id: A0A221P369
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1355015:LK06 RS19010
gene id: 1355015:LK06_RS19010
uniprot id: A0A221P193
names: Function
names: Similarity
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: In the C-terminal section; belongs to the radical SAM superfamily. CofH family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. CofG family.

1355015:LK06 RS20335
gene id: 1355015:LK06_RS20335
uniprot id: A0A221P2Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1355015:LK06 RS06820
gene id: 1355015:LK06_RS06820
uniprot id: A0A221NVD3
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

1355015:LK06 RS27935
gene id: 1355015:LK06_RS27935
uniprot id: A0A221P569
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1355015:LK06 RS27025
gene id: 1355015:LK06_RS27025
uniprot id: A0A221P4Y1
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1355015:LK06 RS21525
gene id: 1355015:LK06_RS21525
uniprot id: A0A221P256
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1355015:LK06 RS20245
gene id: 1355015:LK06_RS20245
uniprot id: A0A221P1U9
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS22095
gene id: 1355015:LK06_RS22095
uniprot id: A0A221P2E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS14780
gene id: 1355015:LK06_RS14780
uniprot id: A0A221NZ66
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS17525
gene id: 1355015:LK06_RS17525
uniprot id: A0A221P0E6
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

1355015:LK06 RS14710
gene id: 1355015:LK06_RS14710
uniprot id: A0A221NZ36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1355015:LK06 RS20405
gene id: 1355015:LK06_RS20405
uniprot id: A0A221P1V2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1355015:LK06 RS30375
gene id: 1355015:LK06_RS30375
uniprot id: A0A221P6G0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS30955
gene id: 1355015:LK06_RS30955
uniprot id: A0A221P6I3
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1355015:LK06 RS13835
gene id: 1355015:LK06_RS13835
uniprot id: A0A221NYY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Membrane

1355015:LK06 RS12460
gene id: 1355015:LK06_RS12460
uniprot id: A0A221NYC4
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1355015:LK06 RS04075
gene id: 1355015:LK06_RS04075
uniprot id: A0A221NVE7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1355015:LK06 RS14940
gene id: 1355015:LK06_RS14940
uniprot id: A0A221NZ77
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1355015:LK06 RS30590
gene id: 1355015:LK06_RS30590
uniprot id: A0A221P6C6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1355015:LK06 RS06840
gene id: 1355015:LK06_RS06840
uniprot id: A0A221NVH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1355015:LK06 RS06460
gene id: 1355015:LK06_RS06460
uniprot id: A0A221NWJ0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1355015:LK06 RS27635
gene id: 1355015:LK06_RS27635
uniprot id: A0A221P595
names: Similarity
messages: Belongs to the PrpD family.

1355015:LK06 RS20680
gene id: 1355015:LK06_RS20680
uniprot id: A0A221P219
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1355015:LK06 RS00570
gene id: 1355015:LK06_RS00570
uniprot id: A0A221NSQ2
names: Similarity
messages: Belongs to the EfeM/EfeO family.

1355015:LK06 RS25835
gene id: 1355015:LK06_RS25835
uniprot id: A0A221P4Q5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1355015:LK06 RS27460
gene id: 1355015:LK06_RS27460
uniprot id: A0A221P955
names: Similarity
messages: Belongs to the IucA/IucC family.

1355015:LK06 RS06215
gene id: 1355015:LK06_RS06215
uniprot id: A0A221NVC8
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1355015:LK06 RS02670
gene id: 1355015:LK06_RS02670
uniprot id: A0A221NTK0
names: Similarity
messages: Belongs to the cytochrome P450 family.

1355015:LK06 RS10125
gene id: 1355015:LK06_RS10125
uniprot id: A0A221NYD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1355015:LK06 RS09895
gene id: 1355015:LK06_RS09895
uniprot id: A0A221NWU9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1355015:LK06 RS05540
gene id: 1355015:LK06_RS05540
uniprot id: A0A221NUZ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.
messages: Belongs to the aromatic-ring hydroxylase family. TetX subfamily.
messages: Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.
messages: Cytoplasm
messages: Monomer.

1355015:LK06 RS24790
gene id: 1355015:LK06_RS24790
uniprot id: A0A221P511
names: Similarity
messages: Belongs to the ribF family.

1355015:LK06 RS24410
gene id: 1355015:LK06_RS24410
uniprot id: A0A221P4U4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1355015:LK06 RS10915
gene id: 1355015:LK06_RS10915
uniprot id: A0A221P8Q4
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1355015:LK06 RS01175
gene id: 1355015:LK06_RS01175
uniprot id: A0A221NSU2
names: Similarity
messages: Belongs to the cytochrome P450 family.

1355015:LK06 RS12275
gene id: 1355015:LK06_RS12275
uniprot id: A0A221NXZ8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1355015:LK06 RS29180
gene id: 1355015:LK06_RS29180
uniprot id: A0A221P659
names: Subunit
messages: Homodimer.

1355015:LK06 RS06085
gene id: 1355015:LK06_RS06085
uniprot id: A0A221NV70
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS12290
gene id: 1355015:LK06_RS12290
uniprot id: A0A221NY99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1355015:LK06 RS13865
gene id: 1355015:LK06_RS13865
uniprot id: A0A221NYQ3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1355015:LK06 RS20035
gene id: 1355015:LK06_RS20035
uniprot id: A0A221P1P7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1355015:LK06 RS07835
gene id: 1355015:LK06_RS07835
uniprot id: A0A221NWG5
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS07665
gene id: 1355015:LK06_RS07665
uniprot id: A0A221NW01
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1355015:LK06 RS06720
gene id: 1355015:LK06_RS06720
uniprot id: A0A221NVJ1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1355015:LK06 RS31440
gene id: 1355015:LK06_RS31440
uniprot id: A0A221P832
names: Subcellular Location Annotation
messages: Cell membrane

1355015:LK06 RS09190
gene id: 1355015:LK06_RS09190
uniprot id: A0A221NWM1
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1355015:LK06 RS11730
gene id: 1355015:LK06_RS11730
uniprot id: A0A221NZ46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1355015:LK06 RS08535
gene id: 1355015:LK06_RS08535
uniprot id: A0A221P7X6
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS09015
gene id: 1355015:LK06_RS09015
uniprot id: A0A221NWQ2
names: Similarity
messages: Belongs to the CdaR family.

1355015:LK06 RS15315
gene id: 1355015:LK06_RS15315
uniprot id: A0A221NZC7
names: Similarity
messages: Belongs to the pirin family.

1355015:LK06 RS22420
gene id: 1355015:LK06_RS22420
uniprot id: A0A221P341
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1355015:LK06 RS05055
gene id: 1355015:LK06_RS05055
uniprot id: A0A221NV28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

1355015:LK06 RS18465
gene id: 1355015:LK06_RS18465
uniprot id: A0A221P0U6
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1355015:LK06 RS02305
gene id: 1355015:LK06_RS02305
uniprot id: A0A221NTE0
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: May form a heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits. May also form a heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1355015:LK06 RS23500
gene id: 1355015:LK06_RS23500
uniprot id: A0A221P9A8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1355015:LK06 RS05360
gene id: 1355015:LK06_RS05360
uniprot id: A0A221NUT4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1355015:LK06 RS05645
gene id: 1355015:LK06_RS05645
uniprot id: A0A221NUX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1355015:LK06 RS06340
gene id: 1355015:LK06_RS06340
uniprot id: A0A221NV51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

1355015:LK06 RS28055
gene id: 1355015:LK06_RS28055
uniprot id: A0A221P5Y5
names: Similarity
messages: Belongs to the peptidase S66 family.

1355015:LK06 RS14910
gene id: 1355015:LK06_RS14910
uniprot id: A0A221NZF4
names: Similarity
messages: Belongs to the cytochrome P450 family.

1355015:LK06 RS04355
gene id: 1355015:LK06_RS04355
uniprot id: A0A221NU74
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS30725
gene id: 1355015:LK06_RS30725
uniprot id: A0A221P6L2
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1355015:LK06 RS24920
gene id: 1355015:LK06_RS24920
uniprot id: A0A221P527
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1355015:LK06 RS11635
gene id: 1355015:LK06_RS11635
uniprot id: A0A221NXS7
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1355015:LK06 RS25775
gene id: 1355015:LK06_RS25775
uniprot id: A0A221P4A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

1355015:LK06 RS26080
gene id: 1355015:LK06_RS26080
uniprot id: A0A221P4B1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1355015:LK06 RS30360
gene id: 1355015:LK06_RS30360
uniprot id: A0A221PAL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1355015:LK06 RS23260
gene id: 1355015:LK06_RS23260
uniprot id: A0A221P3I4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS00380
gene id: 1355015:LK06_RS00380
uniprot id: A0A221NSG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS14750
gene id: 1355015:LK06_RS14750
uniprot id: A0A221NZC9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1355015:LK06 RS11310
gene id: 1355015:LK06_RS11310
uniprot id: A0A221NXL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1355015:LK06 RS27400
gene id: 1355015:LK06_RS27400
uniprot id: A0A221P587
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

1355015:LK06 RS24325
gene id: 1355015:LK06_RS24325
uniprot id: A0A221P3H6
names: Similarity
messages: Belongs to the acylphosphatase family.

1355015:LK06 RS13185
gene id: 1355015:LK06_RS13185
uniprot id: A0A221NZR2
names: Similarity
messages: Belongs to the ComB family.

1355015:LK06 RS27120
gene id: 1355015:LK06_RS27120
uniprot id: A0A221P4W8
names: Similarity
messages: Belongs to the CdaR family.

1355015:LK06 RS11625
gene id: 1355015:LK06_RS11625
uniprot id: A0A221NY74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1355015:LK06 RS07460
gene id: 1355015:LK06_RS07460
uniprot id: A0A221NVN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1355015:LK06 RS03740
gene id: 1355015:LK06_RS03740
uniprot id: A0A221NUF2
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1355015:LK06 RS15635
gene id: 1355015:LK06_RS15635
uniprot id: A0A221NZT3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1355015:LK06 RS10040
gene id: 1355015:LK06_RS10040
uniprot id: A0A221NX23
names: Similarity
messages: Belongs to the peptidase M1 family.

1355015:LK06 RS19730
gene id: 1355015:LK06_RS19730
uniprot id: A0A221P1J9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS09040
gene id: 1355015:LK06_RS09040
uniprot id: A0A221NX29
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1355015:LK06 RS21505
gene id: 1355015:LK06_RS21505
uniprot id: A0A221P3I7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1355015:LK06 RS08865
gene id: 1355015:LK06_RS08865
uniprot id: A0A221NWH7
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1355015:LK06 RS04720
gene id: 1355015:LK06_RS04720
uniprot id: A0A221NUF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1355015:LK06 RS12140
gene id: 1355015:LK06_RS12140
uniprot id: A0A221NXU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

1355015:LK06 RS02300
gene id: 1355015:LK06_RS02300
uniprot id: A0A221NTR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1355015:LK06 RS14010
gene id: 1355015:LK06_RS14010
uniprot id: A0A221NYR4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

1355015:LK06 RS00060
gene id: 1355015:LK06_RS00060
uniprot id: A0A221NSF0
names: Similarity
messages: Belongs to the leucine-binding protein family.

1355015:LK06 RS24390
gene id: 1355015:LK06_RS24390
uniprot id: A0A221P3I9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1355015:LK06 RS06270
gene id: 1355015:LK06_RS06270
uniprot id: A0A221NVA1
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1355015:LK06 RS02995
gene id: 1355015:LK06_RS02995
uniprot id: A0A221P844
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS02515
gene id: 1355015:LK06_RS02515
uniprot id: A0A221NTH7
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

1355015:LK06 RS24495
gene id: 1355015:LK06_RS24495
uniprot id: A0A221P3U6
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1355015:LK06 RS06430
gene id: 1355015:LK06_RS06430
uniprot id: A0A221NV62
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1355015:LK06 RS10120
gene id: 1355015:LK06_RS10120
uniprot id: A0A221NX69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1355015:LK06 RS04275
gene id: 1355015:LK06_RS04275
uniprot id: A0A221NUS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1355015:LK06 RS05265
gene id: 1355015:LK06_RS05265
uniprot id: A0A221NUP0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1355015:LK06 RS18575
gene id: 1355015:LK06_RS18575
uniprot id: A0A221P197
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1355015:LK06 RS18770
gene id: 1355015:LK06_RS18770
uniprot id: A0A221P0Z9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1355015:LK06 RS03245
gene id: 1355015:LK06_RS03245
uniprot id: A0A221NTZ7
names: Similarity
messages: Belongs to the cytochrome P450 family.

1355015:LK06 RS15205
gene id: 1355015:LK06_RS15205
uniprot id: A0A221NZT7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1355015:LK06 RS24850
gene id: 1355015:LK06_RS24850
uniprot id: A0A221P3P6
names: Similarity
messages: Belongs to the WXG100 family.

1355015:LK06 RS06610
gene id: 1355015:LK06_RS06610
uniprot id: A0A221NVE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1355015:LK06 RS05520
gene id: 1355015:LK06_RS05520
uniprot id: A0A221NV22
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1355015:LK06 RS08110
gene id: 1355015:LK06_RS08110
uniprot id: A0A221NWL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1355015:LK06 RS03880
gene id: 1355015:LK06_RS03880
uniprot id: A0A221NU92
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1355015:LK06 RS23550
gene id: 1355015:LK06_RS23550
uniprot id: A0A221P330
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1355015:LK06 RS26425
gene id: 1355015:LK06_RS26425
uniprot id: A0A221P4G6
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1355015:LK06 RS04865
gene id: 1355015:LK06_RS04865
uniprot id: A0A221NUG0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1355015:LK06 RS15105
gene id: 1355015:LK06_RS15105
uniprot id: A0A221NZC1
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1355015:LK06 RS11985
gene id: 1355015:LK06_RS11985
uniprot id: A0A221NY22
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1355015:LK06 RS15035
gene id: 1355015:LK06_RS15035
uniprot id: A0A221NZ79
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS12995
gene id: 1355015:LK06_RS12995
uniprot id: A0A221NYB1
names: Similarity
messages: Belongs to the peptidase A24 family.

1355015:LK06 RS04590
gene id: 1355015:LK06_RS04590
uniprot id: A0A221P8W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1355015:LK06 RS04870
gene id: 1355015:LK06_RS04870
uniprot id: A0A221NUL3
names: Similarity
messages: Belongs to the glutamine synthetase family.

1355015:LK06 RS08100
gene id: 1355015:LK06_RS08100
uniprot id: A0A221NWI1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1355015:LK06 RS08240
gene id: 1355015:LK06_RS08240
uniprot id: A0A221NW92
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1355015:LK06 RS24240
gene id: 1355015:LK06_RS24240
uniprot id: A0A221P3Y6
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

1355015:LK06 RS15630
gene id: 1355015:LK06_RS15630
uniprot id: A0A221NZG3
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS25205
gene id: 1355015:LK06_RS25205
uniprot id: A0A221P4E9
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1355015:LK06 RS09400
gene id: 1355015:LK06_RS09400
uniprot id: A0A221NWW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS27470
gene id: 1355015:LK06_RS27470
uniprot id: A0A221P4X5
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

1355015:LK06 RS27420
gene id: 1355015:LK06_RS27420
uniprot id: A0A221P5F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1355015:LK06 RS06910
gene id: 1355015:LK06_RS06910
uniprot id: A0A221P7Z9
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS24515
gene id: 1355015:LK06_RS24515
uniprot id: A0A221P442
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1355015:LK06 RS06535
gene id: 1355015:LK06_RS06535
uniprot id: A0A221NVC1
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

1355015:LK06 RS07080
gene id: 1355015:LK06_RS07080
uniprot id: A0A221NW07
names: Similarity
messages: Belongs to the TrpC family.

1355015:LK06 RS01060
gene id: 1355015:LK06_RS01060
uniprot id: A0A221NSS0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1355015:LK06 RS28485
gene id: 1355015:LK06_RS28485
uniprot id: A0A221P5F2
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1355015:LK06 RS13445
gene id: 1355015:LK06_RS13445
uniprot id: A0A221NYJ2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1355015:LK06 RS19350
gene id: 1355015:LK06_RS19350
uniprot id: A0A221P2H1
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS22885
gene id: 1355015:LK06_RS22885
uniprot id: A0A221P458
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1355015:LK06 RS07405
gene id: 1355015:LK06_RS07405
uniprot id: A0A221NVX3
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1355015:LK06 RS22565
gene id: 1355015:LK06_RS22565
uniprot id: A0A221P390
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1355015:LK06 RS24205
gene id: 1355015:LK06_RS24205
uniprot id: A0A221P3F1
names: Function
names: Similarity
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.

1355015:LK06 RS27405
gene id: 1355015:LK06_RS27405
uniprot id: A0A221P4W3
names: Function
names: Similarity
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

1355015:LK06 RS25435
gene id: 1355015:LK06_RS25435
uniprot id: A0A221P980
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1355015:LK06 RS12090
gene id: 1355015:LK06_RS12090
uniprot id: A0A221NZ96
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS03745
gene id: 1355015:LK06_RS03745
uniprot id: A0A221NU15
names: Similarity
messages: Belongs to the oxoprolinase family.

1355015:LK06 RS16490
gene id: 1355015:LK06_RS16490
uniprot id: A0A221P0I6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1355015:LK06 RS28680
gene id: 1355015:LK06_RS28680
uniprot id: A0A221P6V4
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS32005
gene id: 1355015:LK06_RS32005
uniprot id: A0A221P7Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

1355015:LK06 RS19490
gene id: 1355015:LK06_RS19490
uniprot id: A0A221P8L3
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1355015:LK06 RS17975
gene id: 1355015:LK06_RS17975
uniprot id: A0A221P1V4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1355015:LK06 RS12780
gene id: 1355015:LK06_RS12780
uniprot id: A0A221NY93
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS23410
gene id: 1355015:LK06_RS23410
uniprot id: A0A221P4D4
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS12265
gene id: 1355015:LK06_RS12265
uniprot id: A0A221NY21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1355015:LK06 RS25915
gene id: 1355015:LK06_RS25915
uniprot id: A0A221P475
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS24060
gene id: 1355015:LK06_RS24060
uniprot id: A0A221P3I5
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1355015:LK06 RS08895
gene id: 1355015:LK06_RS08895
uniprot id: A0A221NWE3
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1355015:LK06 RS23960
gene id: 1355015:LK06_RS23960
uniprot id: A0A221P3V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1355015:LK06 RS29340
gene id: 1355015:LK06_RS29340
uniprot id: A0A221P9J2
names: Similarity
messages: Belongs to the universal stress protein A family.

1355015:LK06 RS06890
gene id: 1355015:LK06_RS06890
uniprot id: A0A221NVM4
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1355015:LK06 RS00040
gene id: 1355015:LK06_RS00040
uniprot id: A0A221NSB0
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS24195
gene id: 1355015:LK06_RS24195
uniprot id: A0A221P3K5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1355015:LK06 RS05150
gene id: 1355015:LK06_RS05150
uniprot id: A0A221NUT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1355015:LK06 RS04790
gene id: 1355015:LK06_RS04790
uniprot id: A0A221NUJ7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1355015:LK06 RS29455
gene id: 1355015:LK06_RS29455
uniprot id: A0A221P674
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1355015:LK06 RS10780
gene id: 1355015:LK06_RS10780
uniprot id: A0A221NX98
names: Similarity
messages: Belongs to the universal stress protein A family.

1355015:LK06 RS20595
gene id: 1355015:LK06_RS20595
uniprot id: A0A221P1Q3
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1355015:LK06 RS02745
gene id: 1355015:LK06_RS02745
uniprot id: A0A221NTP2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1355015:LK06 RS13125
gene id: 1355015:LK06_RS13125
uniprot id: A0A221P881
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1355015:LK06 RS03610
gene id: 1355015:LK06_RS03610
uniprot id: A0A221NUD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1355015:LK06 RS15430
gene id: 1355015:LK06_RS15430
uniprot id: A0A221NZE5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1355015:LK06 RS09485
gene id: 1355015:LK06_RS09485
uniprot id: A0A221NWS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1355015:LK06 RS07025
gene id: 1355015:LK06_RS07025
uniprot id: A0A221NWS8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1355015:LK06 RS18895
gene id: 1355015:LK06_RS18895
uniprot id: A0A221P0X1
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1355015:LK06 RS21815
gene id: 1355015:LK06_RS21815
uniprot id: A0A221P299
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1355015:LK06 RS19880
gene id: 1355015:LK06_RS19880
uniprot id: A0A221P1G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1355015:LK06 RS16185
gene id: 1355015:LK06_RS16185
uniprot id: A0A221P0D5
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

1355015:LK06 RS19710
gene id: 1355015:LK06_RS19710
uniprot id: A0A221P195
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1355015:LK06 RS21955
gene id: 1355015:LK06_RS21955
uniprot id: A0A221P2Y7
names: Similarity
messages: Belongs to the UPF0162 family.

1355015:LK06 RS19940
gene id: 1355015:LK06_RS19940
uniprot id: A0A221P1I0
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1355015:LK06 RS12280
gene id: 1355015:LK06_RS12280
uniprot id: A0A221NY39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1355015:LK06 RS10280
gene id: 1355015:LK06_RS10280
uniprot id: A0A221NX14
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1355015:LK06 RS23060
gene id: 1355015:LK06_RS23060
uniprot id: A0A221P304
names: Similarity
messages: Belongs to the peptidase C40 family.

1355015:LK06 RS01290
gene id: 1355015:LK06_RS01290
uniprot id: A0A221P814
names: Similarity
messages: Belongs to the peptidase S33 family.

1355015:LK06 RS03645
gene id: 1355015:LK06_RS03645
uniprot id: A0A221P7L1
names: Similarity
messages: Belongs to the UPF0749 family.

1355015:LK06 RS12595
gene id: 1355015:LK06_RS12595
uniprot id: A0A221NY66
names: Similarity
messages: Belongs to the UPF0234 family.

1355015:LK06 RS19245
gene id: 1355015:LK06_RS19245
uniprot id: A0A221P8I0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1355015:LK06 RS13530
gene id: 1355015:LK06_RS13530
uniprot id: A0A221NYK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS18690
gene id: 1355015:LK06_RS18690
uniprot id: A0A221P1G2
names: Similarity
messages: Belongs to the citrate synthase family.

1355015:LK06 RS30810
gene id: 1355015:LK06_RS30810
uniprot id: A0A221P6Z0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1355015:LK06 RS00600
gene id: 1355015:LK06_RS00600
uniprot id: A0A221NSM7
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS03240
gene id: 1355015:LK06_RS03240
uniprot id: A0A221NTU2
names: Similarity
messages: Belongs to the thioesterase family.

1355015:LK06 RS29450
gene id: 1355015:LK06_RS29450
uniprot id: A0A221P5W7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1355015:LK06 RS16015
gene id: 1355015:LK06_RS16015
uniprot id: A0A221NZS9
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1355015:LK06 RS15340
gene id: 1355015:LK06_RS15340
uniprot id: A0A221NZN2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1355015:LK06 RS24375
gene id: 1355015:LK06_RS24375
uniprot id: A0A221P434
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS15075
gene id: 1355015:LK06_RS15075
uniprot id: A0A221P0L9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1355015:LK06 RS13910
gene id: 1355015:LK06_RS13910
uniprot id: A0A221NYM8
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1355015:LK06 RS20270
gene id: 1355015:LK06_RS20270
uniprot id: A0A221P8V6
names: Similarity
messages: Belongs to the peptidase C40 family.

1355015:LK06 RS08300
gene id: 1355015:LK06_RS08300
uniprot id: A0A221NWD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1355015:LK06 RS09805
gene id: 1355015:LK06_RS09805
uniprot id: A0A221NX28
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1355015:LK06 RS12405
gene id: 1355015:LK06_RS12405
uniprot id: A0A221NYB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1355015:LK06 RS26350
gene id: 1355015:LK06_RS26350
uniprot id: A0A221P4W9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1355015:LK06 RS10825
gene id: 1355015:LK06_RS10825
uniprot id: A0A221NYP4
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1355015:LK06 RS07995
gene id: 1355015:LK06_RS07995
uniprot id: A0A221NWJ4
names: Similarity
messages: Belongs to the cytochrome P450 family.

1355015:LK06 RS11055
gene id: 1355015:LK06_RS11055
uniprot id: A0A221NXP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1355015:LK06 RS07650
gene id: 1355015:LK06_RS07650
uniprot id: A0A221NVW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1355015:LK06 RS09990
gene id: 1355015:LK06_RS09990
uniprot id: A0A221NX60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1355015:LK06 RS12220
gene id: 1355015:LK06_RS12220
uniprot id: A0A221NXY9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1355015:LK06 RS23540
gene id: 1355015:LK06_RS23540
uniprot id: A0A221P397
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

1355015:LK06 RS11895
gene id: 1355015:LK06_RS11895
uniprot id: A0A221NXT1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1355015:LK06 RS25230
gene id: 1355015:LK06_RS25230
uniprot id: A0A221P411
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1355015:LK06 RS14370
gene id: 1355015:LK06_RS14370
uniprot id: A0A221NYZ1
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS08645
gene id: 1355015:LK06_RS08645
uniprot id: A0A221NWF7
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS25680
gene id: 1355015:LK06_RS25680
uniprot id: A0A221P437
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS26735
gene id: 1355015:LK06_RS26735
uniprot id: A0A221P592
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1355015:LK06 RS23965
gene id: 1355015:LK06_RS23965
uniprot id: A0A221P3A8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS13595
gene id: 1355015:LK06_RS13595
uniprot id: A0A221NYU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

1355015:LK06 RS19375
gene id: 1355015:LK06_RS19375
uniprot id: A0A221P186
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1355015:LK06 RS24875
gene id: 1355015:LK06_RS24875
uniprot id: A0A221P4A4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1355015:LK06 RS15145
gene id: 1355015:LK06_RS15145
uniprot id: A0A221NZS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS20450
gene id: 1355015:LK06_RS20450
uniprot id: A0A221P1X5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1355015:LK06 RS10110
gene id: 1355015:LK06_RS10110
uniprot id: A0A221NX82
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1355015:LK06 RS15030
gene id: 1355015:LK06_RS15030
uniprot id: A0A221NZU1
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS30990
gene id: 1355015:LK06_RS30990
uniprot id: A0A221PAN2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1355015:LK06 RS01715
gene id: 1355015:LK06_RS01715
uniprot id: A0A221NT43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1355015:LK06 RS29620
gene id: 1355015:LK06_RS29620
uniprot id: A0A221P5V2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS03930
gene id: 1355015:LK06_RS03930
uniprot id: A0A221NU27
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1355015:LK06 RS19935
gene id: 1355015:LK06_RS19935
uniprot id: A0A221P1D9
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1355015:LK06 RS28355
gene id: 1355015:LK06_RS28355
uniprot id: A0A221P5S1
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1355015:LK06 RS10035
gene id: 1355015:LK06_RS10035
uniprot id: A0A221NWW9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS24025
gene id: 1355015:LK06_RS24025
uniprot id: A0A221P3G5
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1355015:LK06 RS02310
gene id: 1355015:LK06_RS02310
uniprot id: A0A221NTW9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1355015:LK06 RS04135
gene id: 1355015:LK06_RS04135
uniprot id: A0A221NUN0
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1355015:LK06 RS05560
gene id: 1355015:LK06_RS05560
uniprot id: A0A221P7W7
names: Similarity
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.

1355015:LK06 RS26230
gene id: 1355015:LK06_RS26230
uniprot id: A0A221P4R7
names: Similarity
messages: Belongs to the PrpF family.

1355015:LK06 RS07280
gene id: 1355015:LK06_RS07280
uniprot id: A0A221NVV2
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1355015:LK06 RS13270
gene id: 1355015:LK06_RS13270
uniprot id: A0A221NYP6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1355015:LK06 RS10775
gene id: 1355015:LK06_RS10775
uniprot id: A0A221NXT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1355015:LK06 RS01785
gene id: 1355015:LK06_RS01785
uniprot id: A0A221NT84
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1355015:LK06 RS12550
gene id: 1355015:LK06_RS12550
uniprot id: A0A221NYM1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1355015:LK06 RS02235
gene id: 1355015:LK06_RS02235
uniprot id: A0A221NUL5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1355015:LK06 RS13560
gene id: 1355015:LK06_RS13560
uniprot id: A0A221NZ24
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS19740
gene id: 1355015:LK06_RS19740
uniprot id: A0A221P1A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1355015:LK06 RS04020
gene id: 1355015:LK06_RS04020
uniprot id: A0A221NVD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1355015:LK06 RS07315
gene id: 1355015:LK06_RS07315
uniprot id: A0A221NW69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS19655
gene id: 1355015:LK06_RS19655
uniprot id: A0A221P185
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1355015:LK06 RS12910
gene id: 1355015:LK06_RS12910
uniprot id: A0A221NZM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1355015:LK06 RS30165
gene id: 1355015:LK06_RS30165
uniprot id: A0A221P9Q6
names: Similarity
messages: Belongs to the thioesterase family.

1355015:LK06 RS09800
gene id: 1355015:LK06_RS09800
uniprot id: A0A221NWW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1355015:LK06 RS07485
gene id: 1355015:LK06_RS07485
uniprot id: A0A221NWA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS21435
gene id: 1355015:LK06_RS21435
uniprot id: A0A221P2E4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1355015:LK06 RS05310
gene id: 1355015:LK06_RS05310
uniprot id: A0A221NUN9
names: Similarity
messages: Belongs to the peptidase S45 family.

1355015:LK06 RS01205
gene id: 1355015:LK06_RS01205
uniprot id: A0A221P7R7
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1355015:LK06 RS23975
gene id: 1355015:LK06_RS23975
uniprot id: A0A221P3C1
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS12295
gene id: 1355015:LK06_RS12295
uniprot id: A0A221NXX9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1355015:LK06 RS01180
gene id: 1355015:LK06_RS01180
uniprot id: A0A221NSV8
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1355015:LK06 RS20660
gene id: 1355015:LK06_RS20660
uniprot id: A0A221P1Z9
names: Similarity
messages: Belongs to the FemABX family.

1355015:LK06 RS30195
gene id: 1355015:LK06_RS30195
uniprot id: A0A221PA28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1355015:LK06 RS18245
gene id: 1355015:LK06_RS18245
uniprot id: A0A221P0L0
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1355015:LK06 RS04305
gene id: 1355015:LK06_RS04305
uniprot id: A0A221NUD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1355015:LK06 RS00605
gene id: 1355015:LK06_RS00605
uniprot id: A0A221NTS7
names: Similarity
messages: Belongs to the Fur family.

1355015:LK06 RS12680
gene id: 1355015:LK06_RS12680
uniprot id: A0A221NYF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1355015:LK06 RS14610
gene id: 1355015:LK06_RS14610
uniprot id: A0A221NYY2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1355015:LK06 RS06565
gene id: 1355015:LK06_RS06565
uniprot id: A0A221NV93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1355015:LK06 RS02770
gene id: 1355015:LK06_RS02770
uniprot id: A0A221NTK6
names: Caution
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS01750
gene id: 1355015:LK06_RS01750
uniprot id: A0A221NT34
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1355015:LK06 RS08805
gene id: 1355015:LK06_RS08805
uniprot id: A0A221NXS4
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS07240
gene id: 1355015:LK06_RS07240
uniprot id: A0A221NWX3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1355015:LK06 RS15845
gene id: 1355015:LK06_RS15845
uniprot id: A0A221NZK8
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1355015:LK06 RS11575
gene id: 1355015:LK06_RS11575
uniprot id: A0A221NY65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1355015:LK06 RS03020
gene id: 1355015:LK06_RS03020
uniprot id: A0A221P7E0
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS14445
gene id: 1355015:LK06_RS14445
uniprot id: A0A221NYV2
names: Function
names: Similarity
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

1355015:LK06 RS10380
gene id: 1355015:LK06_RS10380
uniprot id: A0A221NX56
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

1355015:LK06 RS12145
gene id: 1355015:LK06_RS12145
uniprot id: A0A221NY51
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1355015:LK06 RS20890
gene id: 1355015:LK06_RS20890
uniprot id: A0A221P2F8
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Cys-Ser-Gly.
messages: Cytoplasm

1355015:LK06 RS23555
gene id: 1355015:LK06_RS23555
uniprot id: A0A221P392
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS14895
gene id: 1355015:LK06_RS14895
uniprot id: A0A221NZ51
names: Subcellular Location Annotation
messages: Cell membrane

1355015:LK06 RS06690
gene id: 1355015:LK06_RS06690
uniprot id: A0A221P822
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS06645
gene id: 1355015:LK06_RS06645
uniprot id: A0A221NVW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1355015:LK06 RS21370
gene id: 1355015:LK06_RS21370
uniprot id: A0A221P2B9
names: Subcellular Location Annotation
messages: Cytoplasm

1355015:LK06 RS16140
gene id: 1355015:LK06_RS16140
uniprot id: A0A221NZP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1355015:LK06 RS09230
gene id: 1355015:LK06_RS09230
uniprot id: A0A221NWT1
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

1355015:LK06 RS30720
gene id: 1355015:LK06_RS30720
uniprot id: A0A221P9E6
names: Similarity
messages: Belongs to the YciI family.

1355015:LK06 RS12490
gene id: 1355015:LK06_RS12490
uniprot id: A0A221NY69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1355015:LK06 RS22460
gene id: 1355015:LK06_RS22460
uniprot id: A0A221P2K2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1355015:LK06 RS32310
gene id: 1355015:LK06_RS32310
uniprot id: A0A221P8H4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1355015:LK06 RS07340
gene id: 1355015:LK06_RS07340
uniprot id: A0A221NVW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1355015:LK06 RS16125
gene id: 1355015:LK06_RS16125
uniprot id: A0A221P8D2
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

1355015:LK06 RS13740
gene id: 1355015:LK06_RS13740
uniprot id: A0A221NZY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1355015:LK06 RS29030
gene id: 1355015:LK06_RS29030
uniprot id: A0A221P5W9
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS07645
gene id: 1355015:LK06_RS07645
uniprot id: A0A221NWA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

1355015:LK06 RS17255
gene id: 1355015:LK06_RS17255
uniprot id: A0A221P0H3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1355015:LK06 RS29950
gene id: 1355015:LK06_RS29950
uniprot id: A0A221P6L1
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1355015:LK06 RS24635
gene id: 1355015:LK06_RS24635
uniprot id: A0A221P3T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1355015:LK06 RS10145
gene id: 1355015:LK06_RS10145
uniprot id: A0A221NXJ0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1355015:LK06 RS12215
gene id: 1355015:LK06_RS12215
uniprot id: A0A221NYH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1355015:LK06 RS02175
gene id: 1355015:LK06_RS02175
uniprot id: A0A221NTF3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1355015:LK06 RS07320
gene id: 1355015:LK06_RS07320
uniprot id: A0A221NVL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1355015:LK06 RS07150
gene id: 1355015:LK06_RS07150
uniprot id: A0A221NW43
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1355015:LK06 RS04300
gene id: 1355015:LK06_RS04300
uniprot id: A0A221NU67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1355015:LK06 RS03080
gene id: 1355015:LK06_RS03080
uniprot id: A0A221NTP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1355015:LK06 RS10835
gene id: 1355015:LK06_RS10835
uniprot id: A0A221NXD0
names: Subcellular Location Annotation
messages: Cell membrane

1355015:LK06 RS24640
gene id: 1355015:LK06_RS24640
uniprot id: A0A221P485
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1355015:LK06 RS28990
gene id: 1355015:LK06_RS28990
uniprot id: A0A221P5K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1355015:LK06 RS05790
gene id: 1355015:LK06_RS05790
uniprot id: A0A221NW77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1355015:LK06 RS11535
gene id: 1355015:LK06_RS11535
uniprot id: A0A221NXJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1355015:LK06 RS21830
gene id: 1355015:LK06_RS21830
uniprot id: A0A221P2U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS14415
gene id: 1355015:LK06_RS14415
uniprot id: A0A221NZG8
names: Similarity
messages: Belongs to the CsoR family.

1355015:LK06 RS20935
gene id: 1355015:LK06_RS20935
uniprot id: A0A221P2D9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1355015:LK06 RS27055
gene id: 1355015:LK06_RS27055
uniprot id: A0A221P642
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1355015:LK06 RS20815
gene id: 1355015:LK06_RS20815
uniprot id: A0A221P370
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

1355015:LK06 RS20055
gene id: 1355015:LK06_RS20055
uniprot id: A0A221P1K2
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1355015:LK06 RS14090
gene id: 1355015:LK06_RS14090
uniprot id: A0A221NZB5
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS17785
gene id: 1355015:LK06_RS17785
uniprot id: A0A221P0Q1
names: Similarity
messages: Belongs to the peptidase C40 family.

1355015:LK06 RS25905
gene id: 1355015:LK06_RS25905
uniprot id: A0A221P482
names: Similarity
messages: Belongs to the asparagine synthetase family.

1355015:LK06 RS28985
gene id: 1355015:LK06_RS28985
uniprot id: A0A221P5Z2
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1355015:LK06 RS00700
gene id: 1355015:LK06_RS00700
uniprot id: A0A221NSL2
names: Similarity
messages: Belongs to the cytochrome P450 family.

1355015:LK06 RS10285
gene id: 1355015:LK06_RS10285
uniprot id: A0A221NX64
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1355015:LK06 RS05470
gene id: 1355015:LK06_RS05470
uniprot id: A0A221NW25
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

1355015:LK06 RS30160
gene id: 1355015:LK06_RS30160
uniprot id: A0A221P681
names: Similarity
messages: Belongs to the CdaR family.

1355015:LK06 RS06335
gene id: 1355015:LK06_RS06335
uniprot id: A0A221NVE9
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

1355015:LK06 RS13015
gene id: 1355015:LK06_RS13015
uniprot id: A0A221NYD0
names: Subcellular Location Annotation
messages: Cytoplasm

1355015:LK06 RS07620
gene id: 1355015:LK06_RS07620
uniprot id: A0A221NVV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

1355015:LK06 RS06330
gene id: 1355015:LK06_RS06330
uniprot id: A0A221NV90
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

1355015:LK06 RS05635
gene id: 1355015:LK06_RS05635
uniprot id: A0A221NUU1
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1355015:LK06 RS24475
gene id: 1355015:LK06_RS24475
uniprot id: A0A221P456
names: Similarity
messages: Belongs to the DprA/Smf family.

1355015:LK06 RS04800
gene id: 1355015:LK06_RS04800
uniprot id: A0A221NUF0
names: Subcellular Location Annotation
messages: Cell membrane

1355015:LK06 RS00695
gene id: 1355015:LK06_RS00695
uniprot id: A0A221NSL0
names: Similarity
messages: Belongs to the cytochrome P450 family.

1355015:LK06 RS19810
gene id: 1355015:LK06_RS19810
uniprot id: A0A221P1B9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1355015:LK06 RS28235
gene id: 1355015:LK06_RS28235
uniprot id: A0A221P5F9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1355015:LK06 RS14630
gene id: 1355015:LK06_RS14630
uniprot id: A0A221NZ31
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS05735
gene id: 1355015:LK06_RS05735
uniprot id: A0A221NV00
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1355015:LK06 RS25365
gene id: 1355015:LK06_RS25365
uniprot id: A0A221P3Y9
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

1355015:LK06 RS24985
gene id: 1355015:LK06_RS24985
uniprot id: A0A221P435
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1355015:LK06 RS31150
gene id: 1355015:LK06_RS31150
uniprot id: A0A221P7C5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1355015:LK06 RS28515
gene id: 1355015:LK06_RS28515
uniprot id: A0A221P5J7
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS13425
gene id: 1355015:LK06_RS13425
uniprot id: A0A221NZ16
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1355015:LK06 RS24345
gene id: 1355015:LK06_RS24345
uniprot id: A0A221P3R7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1355015:LK06 RS14795
gene id: 1355015:LK06_RS14795
uniprot id: A0A221NZD0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS20740
gene id: 1355015:LK06_RS20740
uniprot id: A0A221P230
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS12880
gene id: 1355015:LK06_RS12880
uniprot id: A0A221NY91
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1355015:LK06 RS06050
gene id: 1355015:LK06_RS06050
uniprot id: A0A221NV76
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1355015:LK06 RS15980
gene id: 1355015:LK06_RS15980
uniprot id: A0A221NZM4
names: Similarity
messages: Belongs to the FemABX family.

1355015:LK06 RS11545
gene id: 1355015:LK06_RS11545
uniprot id: A0A221NZ21
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1355015:LK06 RS16650
gene id: 1355015:LK06_RS16650
uniprot id: A0A221P029
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS19745
gene id: 1355015:LK06_RS19745
uniprot id: A0A221P1F0
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

1355015:LK06 RS08445
gene id: 1355015:LK06_RS08445
uniprot id: A0A221NW63
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1355015:LK06 RS25045
gene id: 1355015:LK06_RS25045
uniprot id: A0A221P3U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1355015:LK06 RS05575
gene id: 1355015:LK06_RS05575
uniprot id: A0A221NVD9
names: Similarity
messages: Belongs to the peptidase S1 family.

1355015:LK06 RS09275
gene id: 1355015:LK06_RS09275
uniprot id: A0A221P7N6
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS22050
gene id: 1355015:LK06_RS22050
uniprot id: A0A221P2P5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1355015:LK06 RS04215
gene id: 1355015:LK06_RS04215
uniprot id: A0A221NU75
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1355015:LK06 RS09980
gene id: 1355015:LK06_RS09980
uniprot id: A0A221NX13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1355015:LK06 RS23745
gene id: 1355015:LK06_RS23745
uniprot id: A0A221P376
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1355015:LK06 RS18175
gene id: 1355015:LK06_RS18175
uniprot id: A0A221P0Q2
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS00665
gene id: 1355015:LK06_RS00665
uniprot id: A0A221NT06
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1355015:LK06 RS31550
gene id: 1355015:LK06_RS31550
uniprot id: A0A221P760
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

1355015:LK06 RS05030
gene id: 1355015:LK06_RS05030
uniprot id: A0A221NUU3
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

1355015:LK06 RS12030
gene id: 1355015:LK06_RS12030
uniprot id: A0A221NXS3
names: Subcellular Location Annotation
messages: Cell membrane

1355015:LK06 RS09880
gene id: 1355015:LK06_RS09880
uniprot id: A0A221NXD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1355015:LK06 RS09650
gene id: 1355015:LK06_RS09650
uniprot id: A0A221NWW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1355015:LK06 RS01895
gene id: 1355015:LK06_RS01895
uniprot id: A0A221NTA2
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1355015:LK06 RS24265
gene id: 1355015:LK06_RS24265
uniprot id: A0A221P3G9
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1355015:LK06 RS15410
gene id: 1355015:LK06_RS15410
uniprot id: A0A221NZC0
names: Similarity
names: Subunit
messages: Belongs to the Bpa family.
messages: Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings.

1355015:LK06 RS12415
gene id: 1355015:LK06_RS12415
uniprot id: A0A221NYB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1355015:LK06 RS03910
gene id: 1355015:LK06_RS03910
uniprot id: A0A221NVB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

1355015:LK06 RS23845
gene id: 1355015:LK06_RS23845
uniprot id: A0A221P3E7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS29495
gene id: 1355015:LK06_RS29495
uniprot id: A0A221P6N3
names: Similarity
messages: Belongs to the SCO1/2 family.

1355015:LK06 RS10105
gene id: 1355015:LK06_RS10105
uniprot id: A0A221NX11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1355015:LK06 RS13095
gene id: 1355015:LK06_RS13095
uniprot id: A0A221NYM6
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS08045
gene id: 1355015:LK06_RS08045
uniprot id: A0A221NWG9
names: Similarity
messages: Belongs to the glutamine synthetase family.

1355015:LK06 RS00295
gene id: 1355015:LK06_RS00295
uniprot id: A0A221NSY7
names: Similarity
messages: Belongs to the universal stress protein A family.

1355015:LK06 RS14425
gene id: 1355015:LK06_RS14425
uniprot id: A0A221NZ06
names: Similarity
messages: Belongs to the thioredoxin family.

1355015:LK06 RS12650
gene id: 1355015:LK06_RS12650
uniprot id: A0A221NY53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1355015:LK06 RS23650
gene id: 1355015:LK06_RS23650
uniprot id: A0A221P3N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

1355015:LK06 RS11175
gene id: 1355015:LK06_RS11175
uniprot id: A0A221NXR1
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS02240
gene id: 1355015:LK06_RS02240
uniprot id: A0A221NTQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

1355015:LK06 RS19380
gene id: 1355015:LK06_RS19380
uniprot id: A0A221P8Z4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1355015:LK06 RS11440
gene id: 1355015:LK06_RS11440
uniprot id: A0A221NY25
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1355015:LK06 RS09810
gene id: 1355015:LK06_RS09810
uniprot id: A0A221NWS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1355015:LK06 RS12495
gene id: 1355015:LK06_RS12495
uniprot id: A0A221NYN1
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS26960
gene id: 1355015:LK06_RS26960
uniprot id: A0A221P4U7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1355015:LK06 RS23900
gene id: 1355015:LK06_RS23900
uniprot id: A0A221P3F4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1355015:LK06 RS27955
gene id: 1355015:LK06_RS27955
uniprot id: A0A221P5H5
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1355015:LK06 RS13420
gene id: 1355015:LK06_RS13420
uniprot id: A0A221NYI9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1355015:LK06 RS10195
gene id: 1355015:LK06_RS10195
uniprot id: A0A221NX26
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1355015:LK06 RS24350
gene id: 1355015:LK06_RS24350
uniprot id: A0A221P3E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1355015:LK06 RS11520
gene id: 1355015:LK06_RS11520
uniprot id: A0A221NXR0
names: Similarity
messages: Belongs to the universal stress protein A family.

1355015:LK06 RS09210
gene id: 1355015:LK06_RS09210
uniprot id: A0A221NWQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

1355015:LK06 RS24300
gene id: 1355015:LK06_RS24300
uniprot id: A0A221P424
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1355015:LK06 RS12040
gene id: 1355015:LK06_RS12040
uniprot id: A0A221NZ92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1355015:LK06 RS20750
gene id: 1355015:LK06_RS20750
uniprot id: A0A221P358
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS10730
gene id: 1355015:LK06_RS10730
uniprot id: A0A221P7S3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1355015:LK06 RS19670
gene id: 1355015:LK06_RS19670
uniprot id: A0A221P1S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1355015:LK06 RS18215
gene id: 1355015:LK06_RS18215
uniprot id: A0A221P179
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1355015:LK06 RS01775
gene id: 1355015:LK06_RS01775
uniprot id: A0A221NTA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1355015:LK06 RS26255
gene id: 1355015:LK06_RS26255
uniprot id: A0A221P4E1
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

1355015:LK06 RS15865
gene id: 1355015:LK06_RS15865
uniprot id: A0A221NZQ6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1355015:LK06 RS06220
gene id: 1355015:LK06_RS06220
uniprot id: A0A221NV32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1355015:LK06 RS06465
gene id: 1355015:LK06_RS06465
uniprot id: A0A221NVR1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1355015:LK06 RS12075
gene id: 1355015:LK06_RS12075
uniprot id: A0A221NY59
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1355015:LK06 RS24810
gene id: 1355015:LK06_RS24810
uniprot id: A0A221P8Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccB family.
messages: Membrane

1355015:LK06 RS25855
gene id: 1355015:LK06_RS25855
uniprot id: A0A221P4B6
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1355015:LK06 RS21335
gene id: 1355015:LK06_RS21335
uniprot id: A0A221P3F9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS26065
gene id: 1355015:LK06_RS26065
uniprot id: A0A221P4T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1355015:LK06 RS20775
gene id: 1355015:LK06_RS20775
uniprot id: A0A221P940
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1355015:LK06 RS07810
gene id: 1355015:LK06_RS07810
uniprot id: A0A221NX77
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1355015:LK06 RS15655
gene id: 1355015:LK06_RS15655
uniprot id: A0A221NZI2
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS26995
gene id: 1355015:LK06_RS26995
uniprot id: A0A221P550
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS09985
gene id: 1355015:LK06_RS09985
uniprot id: A0A221NWZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1355015:LK06 RS13440
gene id: 1355015:LK06_RS13440
uniprot id: A0A221NYK9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1355015:LK06 RS09970
gene id: 1355015:LK06_RS09970
uniprot id: A0A221NXG1
names: Similarity
messages: Belongs to the FPG family.

1355015:LK06 RS01765
gene id: 1355015:LK06_RS01765
uniprot id: A0A221NT46
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS20480
gene id: 1355015:LK06_RS20480
uniprot id: A0A221P1W7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1355015:LK06 RS28595
gene id: 1355015:LK06_RS28595
uniprot id: A0A221P986
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

1355015:LK06 RS27960
gene id: 1355015:LK06_RS27960
uniprot id: A0A221P545
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1355015:LK06 RS28395
gene id: 1355015:LK06_RS28395
uniprot id: A0A221P5E2
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS15955
gene id: 1355015:LK06_RS15955
uniprot id: A0A221P093
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1355015:LK06 RS08025
gene id: 1355015:LK06_RS08025
uniprot id: A0A221NVY8
names: Similarity
messages: Belongs to the ArsC family.

1355015:LK06 RS24385
gene id: 1355015:LK06_RS24385
uniprot id: A0A221P3N1
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1355015:LK06 RS01585
gene id: 1355015:LK06_RS01585
uniprot id: A0A221NTJ2
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1355015:LK06 RS03695
gene id: 1355015:LK06_RS03695
uniprot id: A0A221NUJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1355015:LK06 RS28200
gene id: 1355015:LK06_RS28200
uniprot id: A0A221P5L4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1355015:LK06 RS09635
gene id: 1355015:LK06_RS09635
uniprot id: A0A221NXB5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1355015:LK06 RS10870
gene id: 1355015:LK06_RS10870
uniprot id: A0A221NX89
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS21395
gene id: 1355015:LK06_RS21395
uniprot id: A0A221P2M3
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS19805
gene id: 1355015:LK06_RS19805
uniprot id: A0A221P1X6
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS14595
gene id: 1355015:LK06_RS14595
uniprot id: A0A221NZ39
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS25040
gene id: 1355015:LK06_RS25040
uniprot id: A0A221P3Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1355015:LK06 RS20045
gene id: 1355015:LK06_RS20045
uniprot id: A0A221P1F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1355015:LK06 RS20395
gene id: 1355015:LK06_RS20395
uniprot id: A0A221P2Z5
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1355015:LK06 RS20380
gene id: 1355015:LK06_RS20380
uniprot id: A0A221P1K5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1355015:LK06 RS07245
gene id: 1355015:LK06_RS07245
uniprot id: A0A221NW37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1355015:LK06 RS30025
gene id: 1355015:LK06_RS30025
uniprot id: A0A221P651
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1355015:LK06 RS18820
gene id: 1355015:LK06_RS18820
uniprot id: A0A221P110
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1355015:LK06 RS13350
gene id: 1355015:LK06_RS13350
uniprot id: A0A221NZT0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS05105
gene id: 1355015:LK06_RS05105
uniprot id: A0A221NV37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1355015:LK06 RS13430
gene id: 1355015:LK06_RS13430
uniprot id: A0A221NYH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1355015:LK06 RS09320
gene id: 1355015:LK06_RS09320
uniprot id: A0A221NWL1
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1355015:LK06 RS07005
gene id: 1355015:LK06_RS07005
uniprot id: A0A221NVQ0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1355015:LK06 RS05225
gene id: 1355015:LK06_RS05225
uniprot id: A0A221NUR5
names: Similarity
messages: Belongs to the UPF0225 family.

1355015:LK06 RS05130
gene id: 1355015:LK06_RS05130
uniprot id: A0A221P7N8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

1355015:LK06 RS14945
gene id: 1355015:LK06_RS14945
uniprot id: A0A221NZS2
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1355015:LK06 RS04575
gene id: 1355015:LK06_RS04575
uniprot id: A0A221NUU8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1355015:LK06 RS23545
gene id: 1355015:LK06_RS23545
uniprot id: A0A221P3N2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1355015:LK06 RS02985
gene id: 1355015:LK06_RS02985
uniprot id: A0A221NTM5
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS30320
gene id: 1355015:LK06_RS30320
uniprot id: A0A221P699
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1355015:LK06 RS10430
gene id: 1355015:LK06_RS10430
uniprot id: A0A221NXL4
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS24685
gene id: 1355015:LK06_RS24685
uniprot id: A0A221P476
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1355015:LK06 RS25925
gene id: 1355015:LK06_RS25925
uniprot id: A0A221P462
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1355015:LK06 RS19575
gene id: 1355015:LK06_RS19575
uniprot id: A0A221P178
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1355015:LK06 RS15990
gene id: 1355015:LK06_RS15990
uniprot id: A0A221P123
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1355015:LK06 RS08330
gene id: 1355015:LK06_RS08330
uniprot id: A0A221NW84
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1355015:LK06 RS06505
gene id: 1355015:LK06_RS06505
uniprot id: A0A221NVH1
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS05430
gene id: 1355015:LK06_RS05430
uniprot id: A0A221NVB9
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS24535
gene id: 1355015:LK06_RS24535
uniprot id: A0A221P3R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1355015:LK06 RS07295
gene id: 1355015:LK06_RS07295
uniprot id: A0A221P8G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell membrane
messages: Essential cell division protein.

1355015:LK06 RS09355
gene id: 1355015:LK06_RS09355
uniprot id: A0A221NY09
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1355015:LK06 RS28650
gene id: 1355015:LK06_RS28650
uniprot id: A0A221P5I0
names: Similarity
messages: Belongs to the peptidase M1 family.

1355015:LK06 RS15050
gene id: 1355015:LK06_RS15050
uniprot id: A0A221P816
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS25480
gene id: 1355015:LK06_RS25480
uniprot id: A0A221P454
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1355015:LK06 RS15890
gene id: 1355015:LK06_RS15890
uniprot id: A0A221P052
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1355015:LK06 RS08170
gene id: 1355015:LK06_RS08170
uniprot id: A0A221NW81
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS11280
gene id: 1355015:LK06_RS11280
uniprot id: A0A221NXS8
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS17690
gene id: 1355015:LK06_RS17690
uniprot id: A0A221P105
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS07450
gene id: 1355015:LK06_RS07450
uniprot id: A0A221NVS4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1355015:LK06 RS07625
gene id: 1355015:LK06_RS07625
uniprot id: A0A221NW09
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

1355015:LK06 RS29310
gene id: 1355015:LK06_RS29310
uniprot id: A0A221P678
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

1355015:LK06 RS17665
gene id: 1355015:LK06_RS17665
uniprot id: A0A221P0B6
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

1355015:LK06 RS28380
gene id: 1355015:LK06_RS28380
uniprot id: A0A221P9H2
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1355015:LK06 RS12895
gene id: 1355015:LK06_RS12895
uniprot id: A0A221NYJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1355015:LK06 RS17885
gene id: 1355015:LK06_RS17885
uniprot id: A0A221P0F9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1355015:LK06 RS04890
gene id: 1355015:LK06_RS04890
uniprot id: A0A221NV30
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS19360
gene id: 1355015:LK06_RS19360
uniprot id: A0A221P1E1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1355015:LK06 RS28585
gene id: 1355015:LK06_RS28585
uniprot id: A0A221P5H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1355015:LK06 RS19835
gene id: 1355015:LK06_RS19835
uniprot id: A0A221P1N1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS17560
gene id: 1355015:LK06_RS17560
uniprot id: A0A221P1P4
names: Subcellular Location Annotation
messages: Cell membrane

1355015:LK06 RS29870
gene id: 1355015:LK06_RS29870
uniprot id: A0A221P6K3
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1355015:LK06 RS24245
gene id: 1355015:LK06_RS24245
uniprot id: A0A221P3L5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1355015:LK06 RS19050
gene id: 1355015:LK06_RS19050
uniprot id: A0A221P1L8
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS24750
gene id: 1355015:LK06_RS24750
uniprot id: A0A221P4A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1355015:LK06 RS08235
gene id: 1355015:LK06_RS08235
uniprot id: A0A221NW28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS25985
gene id: 1355015:LK06_RS25985
uniprot id: A0A221P5J6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1355015:LK06 RS26415
gene id: 1355015:LK06_RS26415
uniprot id: A0A221P4L3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1355015:LK06 RS00860
gene id: 1355015:LK06_RS00860
uniprot id: A0A221NSK5
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1355015:LK06 RS05340
gene id: 1355015:LK06_RS05340
uniprot id: A0A221P8Y1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1355015:LK06 RS12210
gene id: 1355015:LK06_RS12210
uniprot id: A0A221NY12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1355015:LK06 RS19460
gene id: 1355015:LK06_RS19460
uniprot id: A0A221P196
names: Similarity
messages: Belongs to the MT-A70-like family.

1355015:LK06 RS11210
gene id: 1355015:LK06_RS11210
uniprot id: A0A221NXG7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1355015:LK06 RS30330
gene id: 1355015:LK06_RS30330
uniprot id: A0A221P655
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1355015:LK06 RS02405
gene id: 1355015:LK06_RS02405
uniprot id: A0A221NUN7
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS05345
gene id: 1355015:LK06_RS05345
uniprot id: A0A221NUW7
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

1355015:LK06 RS27905
gene id: 1355015:LK06_RS27905
uniprot id: A0A221P5K2
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

1355015:LK06 RS23735
gene id: 1355015:LK06_RS23735
uniprot id: A0A221P362
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1355015:LK06 RS19330
gene id: 1355015:LK06_RS19330
uniprot id: A0A221P1E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1355015:LK06 RS00625
gene id: 1355015:LK06_RS00625
uniprot id: A0A221NSK0
names: Function
messages: Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).

1355015:LK06 RS28500
gene id: 1355015:LK06_RS28500
uniprot id: A0A221P5U2
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

1355015:LK06 RS24605
gene id: 1355015:LK06_RS24605
uniprot id: A0A221P3X1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1355015:LK06 RS03935
gene id: 1355015:LK06_RS03935
uniprot id: A0A221P7C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1355015:LK06 RS04095
gene id: 1355015:LK06_RS04095
uniprot id: A0A221NU54
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

1355015:LK06 RS21665
gene id: 1355015:LK06_RS21665
uniprot id: A0A221P973
names: Similarity
messages: Belongs to the UPF0167 family.

1355015:LK06 RS23770
gene id: 1355015:LK06_RS23770
uniprot id: A0A221P4I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS12665
gene id: 1355015:LK06_RS12665
uniprot id: A0A221NY78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1355015:LK06 RS23795
gene id: 1355015:LK06_RS23795
uniprot id: A0A221P374
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1355015:LK06 RS07195
gene id: 1355015:LK06_RS07195
uniprot id: A0A221NVN3
names: Subcellular Location Annotation
messages: Cytoplasm

1355015:LK06 RS02895
gene id: 1355015:LK06_RS02895
uniprot id: A0A221NTQ9
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1355015:LK06 RS12675
gene id: 1355015:LK06_RS12675
uniprot id: A0A221NY35
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1355015:LK06 RS19585
gene id: 1355015:LK06_RS19585
uniprot id: A0A221P1B5
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1355015:LK06 RS12240
gene id: 1355015:LK06_RS12240
uniprot id: A0A221NXW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1355015:LK06 RS31180
gene id: 1355015:LK06_RS31180
uniprot id: A0A221P716
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1355015:LK06 RS14365
gene id: 1355015:LK06_RS14365
uniprot id: A0A221NYZ6
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.

1355015:LK06 RS13010
gene id: 1355015:LK06_RS13010
uniprot id: A0A221NYE9
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1355015:LK06 RS13610
gene id: 1355015:LK06_RS13610
uniprot id: A0A221NYU5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1355015:LK06 RS27540
gene id: 1355015:LK06_RS27540
uniprot id: A0A221P5E5
names: Subunit
messages: Homotetramer.

1355015:LK06 RS30665
gene id: 1355015:LK06_RS30665
uniprot id: A0A221P6E8
names: Similarity
messages: Belongs to the asparagine synthetase family.

1355015:LK06 RS08840
gene id: 1355015:LK06_RS08840
uniprot id: A0A221NWN6
names: Similarity
messages: Belongs to the pirin family.

1355015:LK06 RS10130
gene id: 1355015:LK06_RS10130
uniprot id: A0A221NXG5
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1355015:LK06 RS24725
gene id: 1355015:LK06_RS24725
uniprot id: A0A221P3M3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1355015:LK06 RS05555
gene id: 1355015:LK06_RS05555
uniprot id: A0A221P7F9
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1355015:LK06 RS30820
gene id: 1355015:LK06_RS30820
uniprot id: A0A221P779
names: Similarity
messages: Belongs to the melC1 family.

1355015:LK06 RS20695
gene id: 1355015:LK06_RS20695
uniprot id: A0A221P204
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS18300
gene id: 1355015:LK06_RS18300
uniprot id: A0A221P0R8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1355015:LK06 RS07110
gene id: 1355015:LK06_RS07110
uniprot id: A0A221P859
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1355015:LK06 RS00845
gene id: 1355015:LK06_RS00845
uniprot id: A0A221NSP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EfeM/EfeO family.
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1355015:LK06 RS30505
gene id: 1355015:LK06_RS30505
uniprot id: A0A221P6U0
names: Similarity
messages: Belongs to the creatininase superfamily.

1355015:LK06 RS06285
gene id: 1355015:LK06_RS06285
uniprot id: A0A221NV41
names: Similarity
messages: Belongs to the CobH/CbiC family.

1355015:LK06 RS30205
gene id: 1355015:LK06_RS30205
uniprot id: A0A221P959
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1355015:LK06 RS12310
gene id: 1355015:LK06_RS12310
uniprot id: A0A221NYI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1355015:LK06 RS12515
gene id: 1355015:LK06_RS12515
uniprot id: A0A221NYD3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1355015:LK06 RS26220
gene id: 1355015:LK06_RS26220
uniprot id: A0A221P4N8
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1355015:LK06 RS19830
gene id: 1355015:LK06_RS19830
uniprot id: A0A221P1B4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1355015:LK06 RS05880
gene id: 1355015:LK06_RS05880
uniprot id: A0A221NUX2
names: Similarity
messages: Belongs to the UPF0098 family.

1355015:LK06 RS20225
gene id: 1355015:LK06_RS20225
uniprot id: A0A221P1I8
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1355015:LK06 RS12095
gene id: 1355015:LK06_RS12095
uniprot id: A0A221NYE1
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1355015:LK06 RS23320
gene id: 1355015:LK06_RS23320
uniprot id: A0A221P3J4
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

1355015:LK06 RS08105
gene id: 1355015:LK06_RS08105
uniprot id: A0A221NW44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1355015:LK06 RS07580
gene id: 1355015:LK06_RS07580
uniprot id: A0A221NW03
names: Similarity
messages: Belongs to the peptidase C40 family.

1355015:LK06 RS18410
gene id: 1355015:LK06_RS18410
uniprot id: A0A221P0U1
names: Similarity
messages: Belongs to the CutC family.

1355015:LK06 RS24035
gene id: 1355015:LK06_RS24035
uniprot id: A0A221P3L3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits.
messages: In the C-terminal section; belongs to the urease beta subunit family.
messages: In the N-terminal section; belongs to the urease gamma subunit family.

1355015:LK06 RS24755
gene id: 1355015:LK06_RS24755
uniprot id: A0A221P3P5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1355015:LK06 RS20710
gene id: 1355015:LK06_RS20710
uniprot id: A0A221P1S2
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS03620
gene id: 1355015:LK06_RS03620
uniprot id: A0A221NUI1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1355015:LK06 RS28565
gene id: 1355015:LK06_RS28565
uniprot id: A0A221P921
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1355015:LK06 RS05965
gene id: 1355015:LK06_RS05965
uniprot id: A0A221NUY6
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS30770
gene id: 1355015:LK06_RS30770
uniprot id: A0A221P770
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS04285
gene id: 1355015:LK06_RS04285
uniprot id: A0A221NUC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1355015:LK06 RS26395
gene id: 1355015:LK06_RS26395
uniprot id: A0A221P4V2
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS15265
gene id: 1355015:LK06_RS15265
uniprot id: A0A221NZY2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1355015:LK06 RS30175
gene id: 1355015:LK06_RS30175
uniprot id: A0A221P9D5
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS17840
gene id: 1355015:LK06_RS17840
uniprot id: A0A221P0F0
names: Subcellular Location Annotation
messages: Cell membrane

1355015:LK06 RS24395
gene id: 1355015:LK06_RS24395
uniprot id: A0A221P3S5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1355015:LK06 RS01530
gene id: 1355015:LK06_RS01530
uniprot id: A0A221NTI2
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine.

1355015:LK06 RS02060
gene id: 1355015:LK06_RS02060
uniprot id: A0A221NTF5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1355015:LK06 RS18850
gene id: 1355015:LK06_RS18850
uniprot id: A0A221P291
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1355015:LK06 RS25455
gene id: 1355015:LK06_RS25455
uniprot id: A0A221P5A8
names: Subcellular Location Annotation
messages: Cell membrane

1355015:LK06 RS17490
gene id: 1355015:LK06_RS17490
uniprot id: A0A221P089
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1355015:LK06 RS23700
gene id: 1355015:LK06_RS23700
uniprot id: A0A221P3F0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1355015:LK06 RS12905
gene id: 1355015:LK06_RS12905
uniprot id: A0A221NYJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1355015:LK06 RS03110
gene id: 1355015:LK06_RS03110
uniprot id: A0A221NTP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1355015:LK06 RS20065
gene id: 1355015:LK06_RS20065
uniprot id: A0A221P1S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

1355015:LK06 RS14545
gene id: 1355015:LK06_RS14545
uniprot id: A0A221NZ91
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1355015:LK06 RS23910
gene id: 1355015:LK06_RS23910
uniprot id: A0A221P393
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS26620
gene id: 1355015:LK06_RS26620
uniprot id: A0A221P507
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS00855
gene id: 1355015:LK06_RS00855
uniprot id: A0A221NSU8
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1355015:LK06 RS20585
gene id: 1355015:LK06_RS20585
uniprot id: A0A221P1Y4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1355015:LK06 RS20285
gene id: 1355015:LK06_RS20285
uniprot id: A0A221P1U0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1355015:LK06 RS01265
gene id: 1355015:LK06_RS01265
uniprot id: A0A221NTA4
names: Similarity
messages: Belongs to the cytochrome P450 family.

1355015:LK06 RS12270
gene id: 1355015:LK06_RS12270
uniprot id: A0A221NYI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1355015:LK06 RS20725
gene id: 1355015:LK06_RS20725
uniprot id: A0A221P1U2
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS09905
gene id: 1355015:LK06_RS09905
uniprot id: A0A221NWY3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1355015:LK06 RS02765
gene id: 1355015:LK06_RS02765
uniprot id: A0A221NU53
names: Caution
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS09920
gene id: 1355015:LK06_RS09920
uniprot id: A0A221NWU7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1355015:LK06 RS06595
gene id: 1355015:LK06_RS06595
uniprot id: A0A221NV95
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS17315
gene id: 1355015:LK06_RS17315
uniprot id: A0A221P0C0
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1355015:LK06 RS04110
gene id: 1355015:LK06_RS04110
uniprot id: A0A221NUD4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS03580
gene id: 1355015:LK06_RS03580
uniprot id: A0A221NU44
names: Similarity
messages: Belongs to the universal stress protein A family.

1355015:LK06 RS04080
gene id: 1355015:LK06_RS04080
uniprot id: A0A221NUL1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS02410
gene id: 1355015:LK06_RS02410
uniprot id: A0A221NTT9
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS08520
gene id: 1355015:LK06_RS08520
uniprot id: A0A221NWT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1355015:LK06 RS17055
gene id: 1355015:LK06_RS17055
uniprot id: A0A221P0F3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Cytoplasm
messages: Homodimer.

1355015:LK06 RS07045
gene id: 1355015:LK06_RS07045
uniprot id: A0A221NVG3
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS21165
gene id: 1355015:LK06_RS21165
uniprot id: A0A221P221
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS31535
gene id: 1355015:LK06_RS31535
uniprot id: A0A221P6S1
names: Similarity
messages: Belongs to the acyltransferase PapA5 family.

1355015:LK06 RS29610
gene id: 1355015:LK06_RS29610
uniprot id: A0A221P5Y8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1355015:LK06 RS31015
gene id: 1355015:LK06_RS31015
uniprot id: A0A221P6R5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1355015:LK06 RS16710
gene id: 1355015:LK06_RS16710
uniprot id: A0A221P038
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1355015:LK06 RS03825
gene id: 1355015:LK06_RS03825
uniprot id: A0A221NU30
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1355015:LK06 RS13990
gene id: 1355015:LK06_RS13990
uniprot id: A0A221P035
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1355015:LK06 RS21105
gene id: 1355015:LK06_RS21105
uniprot id: A0A221P237
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS06315
gene id: 1355015:LK06_RS06315
uniprot id: A0A221NVQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS05585
gene id: 1355015:LK06_RS05585
uniprot id: A0A221NUZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1355015:LK06 RS21995
gene id: 1355015:LK06_RS21995
uniprot id: A0A221P3S3
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1355015:LK06 RS23330
gene id: 1355015:LK06_RS23330
uniprot id: A0A221P348
names: Subcellular Location Annotation
messages: Cell membrane

1355015:LK06 RS00130
gene id: 1355015:LK06_RS00130
uniprot id: A0A221NSG1
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1355015:LK06 RS28785
gene id: 1355015:LK06_RS28785
uniprot id: A0A221P6X7
names: Similarity
messages: Belongs to the glycosyl hydrolase.

1355015:LK06 RS12320
gene id: 1355015:LK06_RS12320
uniprot id: A0A221NYK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1355015:LK06 RS09615
gene id: 1355015:LK06_RS09615
uniprot id: A0A221NY47
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1355015:LK06 RS26405
gene id: 1355015:LK06_RS26405
uniprot id: A0A221P5S4
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS06945
gene id: 1355015:LK06_RS06945
uniprot id: A0A221NVN8
names: Similarity
messages: Belongs to the group II decarboxylase family.

1355015:LK06 RS04210
gene id: 1355015:LK06_RS04210
uniprot id: A0A221P879
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1355015:LK06 RS15620
gene id: 1355015:LK06_RS15620
uniprot id: A0A221NZM1
names: Similarity
messages: Belongs to the UPF0749 family.

1355015:LK06 RS30490
gene id: 1355015:LK06_RS30490
uniprot id: A0A221P9B0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1355015:LK06 RS22025
gene id: 1355015:LK06_RS22025
uniprot id: A0A221P2I8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1355015:LK06 RS24765
gene id: 1355015:LK06_RS24765
uniprot id: A0A221P3Q8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1355015:LK06 RS25200
gene id: 1355015:LK06_RS25200
uniprot id: A0A221P9A1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1355015:LK06 RS10985
gene id: 1355015:LK06_RS10985
uniprot id: A0A221NXE4
names: Similarity
messages: Belongs to the peptidase C40 family.

1355015:LK06 RS28475
gene id: 1355015:LK06_RS28475
uniprot id: A0A221P5E6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1355015:LK06 RS11690
gene id: 1355015:LK06_RS11690
uniprot id: A0A221NXQ0
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1355015:LK06 RS11245
gene id: 1355015:LK06_RS11245
uniprot id: A0A221NYW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1355015:LK06 RS06440
gene id: 1355015:LK06_RS06440
uniprot id: A0A221NVA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS24415
gene id: 1355015:LK06_RS24415
uniprot id: A0A221P423
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

1355015:LK06 RS07860
gene id: 1355015:LK06_RS07860
uniprot id: A0A221NW53
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1355015:LK06 RS01045
gene id: 1355015:LK06_RS01045
uniprot id: A0A221NSR6
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

1355015:LK06 RS08615
gene id: 1355015:LK06_RS08615
uniprot id: A0A221NWH9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1355015:LK06 RS08855
gene id: 1355015:LK06_RS08855
uniprot id: A0A221NXT3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1355015:LK06 RS28840
gene id: 1355015:LK06_RS28840
uniprot id: A0A221P6Y7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

1355015:LK06 RS15850
gene id: 1355015:LK06_RS15850
uniprot id: A0A221P073
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1355015:LK06 RS16005
gene id: 1355015:LK06_RS16005
uniprot id: A0A221P0A3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1355015:LK06 RS15325
gene id: 1355015:LK06_RS15325
uniprot id: A0A221NZC2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1355015:LK06 RS28050
gene id: 1355015:LK06_RS28050
uniprot id: A0A221P5C8
names: Similarity
messages: Belongs to the peptidase S9C family.

1355015:LK06 RS20880
gene id: 1355015:LK06_RS20880
uniprot id: A0A221P2C9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1355015:LK06 RS11870
gene id: 1355015:LK06_RS11870
uniprot id: A0A221NZ65
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1355015:LK06 RS27145
gene id: 1355015:LK06_RS27145
uniprot id: A0A221P540
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1355015:LK06 RS09290
gene id: 1355015:LK06_RS09290
uniprot id: A0A221NWU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1355015:LK06 RS26950
gene id: 1355015:LK06_RS26950
uniprot id: A0A221P622
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1355015:LK06 RS29405
gene id: 1355015:LK06_RS29405
uniprot id: A0A221P625
names: Similarity
messages: Belongs to the cytochrome P450 family.

1355015:LK06 RS19820
gene id: 1355015:LK06_RS19820
uniprot id: A0A221P1F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1355015:LK06 RS12015
gene id: 1355015:LK06_RS12015
uniprot id: A0A221NXY7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1355015:LK06 RS20810
gene id: 1355015:LK06_RS20810
uniprot id: A0A221P239
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1355015:LK06 RS28330
gene id: 1355015:LK06_RS28330
uniprot id: A0A221P5D2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1355015:LK06 RS25525
gene id: 1355015:LK06_RS25525
uniprot id: A0A221P417
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1355015:LK06 RS13625
gene id: 1355015:LK06_RS13625
uniprot id: A0A221NYL4
names: Subcellular Location Annotation
messages: Cell membrane

1355015:LK06 RS29470
gene id: 1355015:LK06_RS29470
uniprot id: A0A221P6A4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1355015:LK06 RS06030
gene id: 1355015:LK06_RS06030
uniprot id: A0A221NV60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1355015:LK06 RS22350
gene id: 1355015:LK06_RS22350
uniprot id: A0A221P2V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS03315
gene id: 1355015:LK06_RS03315
uniprot id: A0A221NTS4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1355015:LK06 RS12950
gene id: 1355015:LK06_RS12950
uniprot id: A0A221NY81
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1355015:LK06 RS07065
gene id: 1355015:LK06_RS07065
uniprot id: A0A221NVH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1355015:LK06 RS30740
gene id: 1355015:LK06_RS30740
uniprot id: A0A221P6B8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS12180
gene id: 1355015:LK06_RS12180
uniprot id: A0A221NXZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1355015:LK06 RS13415
gene id: 1355015:LK06_RS13415
uniprot id: A0A221NZ01
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1355015:LK06 RS25020
gene id: 1355015:LK06_RS25020
uniprot id: A0A221P3Y8
names: Similarity
messages: Belongs to the FPG family.

1355015:LK06 RS16515
gene id: 1355015:LK06_RS16515
uniprot id: A0A221P008
names: Similarity
messages: Belongs to the protease inhibitor I16 (SSI) family.

1355015:LK06 RS02315
gene id: 1355015:LK06_RS02315
uniprot id: A0A221NTD1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1355015:LK06 RS21045
gene id: 1355015:LK06_RS21045
uniprot id: A0A221P1Y2
names: Similarity
messages: Belongs to the thioesterase family.

1355015:LK06 RS18135
gene id: 1355015:LK06_RS18135
uniprot id: A0A221P0V9
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS20180
gene id: 1355015:LK06_RS20180
uniprot id: A0A221P1H5
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1355015:LK06 RS10770
gene id: 1355015:LK06_RS10770
uniprot id: A0A221NXB6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1355015:LK06 RS20705
gene id: 1355015:LK06_RS20705
uniprot id: A0A221P2C1
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

1355015:LK06 RS08415
gene id: 1355015:LK06_RS08415
uniprot id: A0A221NW93
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1355015:LK06 RS23630
gene id: 1355015:LK06_RS23630
uniprot id: A0A221P3E0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

1355015:LK06 RS14915
gene id: 1355015:LK06_RS14915
uniprot id: A0A221NZ30
names: Similarity
messages: Belongs to the cytochrome P450 family.

1355015:LK06 RS23470
gene id: 1355015:LK06_RS23470
uniprot id: A0A221P388
names: Similarity
messages: Belongs to the UPF0045 family.

1355015:LK06 RS02905
gene id: 1355015:LK06_RS02905
uniprot id: A0A221NTU3
names: Similarity
messages: Belongs to the cytochrome P450 family.

1355015:LK06 RS21365
gene id: 1355015:LK06_RS21365
uniprot id: A0A221P262
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.

1355015:LK06 RS14490
gene id: 1355015:LK06_RS14490
uniprot id: A0A221NZ10
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

1355015:LK06 RS27670
gene id: 1355015:LK06_RS27670
uniprot id: A0A221P6F3
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

1355015:LK06 RS31355
gene id: 1355015:LK06_RS31355
uniprot id: A0A221P747
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1355015:LK06 RS05935
gene id: 1355015:LK06_RS05935
uniprot id: A0A221NUY1
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS26445
gene id: 1355015:LK06_RS26445
uniprot id: A0A221P4F5
names: Similarity
messages: Belongs to the peptidase S8 family.

1355015:LK06 RS15480
gene id: 1355015:LK06_RS15480
uniprot id: A0A221NZF5
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS10075
gene id: 1355015:LK06_RS10075
uniprot id: A0A221NXG0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1355015:LK06 RS02250
gene id: 1355015:LK06_RS02250
uniprot id: A0A221NTW0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS00025
gene id: 1355015:LK06_RS00025
uniprot id: A0A221NSU6
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS09960
gene id: 1355015:LK06_RS09960
uniprot id: A0A221NWY9
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

1355015:LK06 RS10675
gene id: 1355015:LK06_RS10675
uniprot id: A0A221NXH2
names: Similarity
messages: Belongs to the TPP enzyme family.

1355015:LK06 RS22850
gene id: 1355015:LK06_RS22850
uniprot id: A0A221P2S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1355015:LK06 RS07695
gene id: 1355015:LK06_RS07695
uniprot id: A0A221NX55
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1355015:LK06 RS28910
gene id: 1355015:LK06_RS28910
uniprot id: A0A221P6D0
names: Similarity
messages: Belongs to the glutamine synthetase family.

1355015:LK06 RS12400
gene id: 1355015:LK06_RS12400
uniprot id: A0A221NY38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1355015:LK06 RS28695
gene id: 1355015:LK06_RS28695
uniprot id: A0A221P691
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1355015:LK06 RS04290
gene id: 1355015:LK06_RS04290
uniprot id: A0A221NUB2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1355015:LK06 RS22075
gene id: 1355015:LK06_RS22075
uniprot id: A0A221P2E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1355015:LK06 RS23225
gene id: 1355015:LK06_RS23225
uniprot id: A0A221P2W7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS05010
gene id: 1355015:LK06_RS05010
uniprot id: A0A221NUJ4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1355015:LK06 RS17810
gene id: 1355015:LK06_RS17810
uniprot id: A0A221P0H4
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS11435
gene id: 1355015:LK06_RS11435
uniprot id: A0A221NYZ7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1355015:LK06 RS09445
gene id: 1355015:LK06_RS09445
uniprot id: A0A221NWT8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1355015:LK06 RS20720
gene id: 1355015:LK06_RS20720
uniprot id: A0A221P1X8
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1355015:LK06 RS24290
gene id: 1355015:LK06_RS24290
uniprot id: A0A221P3Z7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1355015:LK06 RS25355
gene id: 1355015:LK06_RS25355
uniprot id: A0A221P433
names: Similarity
messages: Belongs to the citrate synthase family.

1355015:LK06 RS26625
gene id: 1355015:LK06_RS26625
uniprot id: A0A221P4P0
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS22760
gene id: 1355015:LK06_RS22760
uniprot id: A0A221P2Z7
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS14520
gene id: 1355015:LK06_RS14520
uniprot id: A0A221NZ09
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1355015:LK06 RS01655
gene id: 1355015:LK06_RS01655
uniprot id: A0A221NT27
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS29665
gene id: 1355015:LK06_RS29665
uniprot id: A0A221P662
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1355015:LK06 RS11230
gene id: 1355015:LK06_RS11230
uniprot id: A0A221NXE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1355015:LK06 RS02760
gene id: 1355015:LK06_RS02760
uniprot id: A0A221NTL5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1355015:LK06 RS07050
gene id: 1355015:LK06_RS07050
uniprot id: A0A221NVN7
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1355015:LK06 RS22340
gene id: 1355015:LK06_RS22340
uniprot id: A0A221P2S9
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1355015:LK06 RS10345
gene id: 1355015:LK06_RS10345
uniprot id: A0A221NX74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1355015:LK06 RS04085
gene id: 1355015:LK06_RS04085
uniprot id: A0A221NU70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1355015:LK06 RS20175
gene id: 1355015:LK06_RS20175
uniprot id: A0A221P1U3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1355015:LK06 RS11660
gene id: 1355015:LK06_RS11660
uniprot id: A0A221NZ40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1355015:LK06 RS06630
gene id: 1355015:LK06_RS06630
uniprot id: A0A221NWL7
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1355015:LK06 RS12190
gene id: 1355015:LK06_RS12190
uniprot id: A0A221NXV9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1355015:LK06 RS04190
gene id: 1355015:LK06_RS04190
uniprot id: A0A221NVG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1355015:LK06 RS07140
gene id: 1355015:LK06_RS07140
uniprot id: A0A221NW20
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1355015:LK06 RS02210
gene id: 1355015:LK06_RS02210
uniprot id: A0A221NTD0
names: Similarity
messages: Belongs to the cytochrome P450 family.

1355015:LK06 RS01660
gene id: 1355015:LK06_RS01660
uniprot id: A0A221NT31
names: Similarity
messages: Belongs to the CapA family.

1355015:LK06 RS06680
gene id: 1355015:LK06_RS06680
uniprot id: A0A221NVI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1355015:LK06 RS31600
gene id: 1355015:LK06_RS31600
uniprot id: A0A221P6U8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1355015:LK06 RS04810
gene id: 1355015:LK06_RS04810
uniprot id: A0A221NVR9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1355015:LK06 RS22355
gene id: 1355015:LK06_RS22355
uniprot id: A0A221P3Y3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1355015:LK06 RS11670
gene id: 1355015:LK06_RS11670
uniprot id: A0A221NY61
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1355015:LK06 RS09335
gene id: 1355015:LK06_RS09335
uniprot id: A0A221NWP5
names: Similarity
messages: Belongs to the DapA family.

1355015:LK06 RS12300
gene id: 1355015:LK06_RS12300
uniprot id: A0A221NY90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1355015:LK06 RS05235
gene id: 1355015:LK06_RS05235
uniprot id: A0A221P7J2
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

1355015:LK06 RS08795
gene id: 1355015:LK06_RS08795
uniprot id: A0A221NWC5
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1355015:LK06 RS18120
gene id: 1355015:LK06_RS18120
uniprot id: A0A221P0N3
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1355015:LK06 RS02225
gene id: 1355015:LK06_RS02225
uniprot id: A0A221NTA3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1355015:LK06 RS18760
gene id: 1355015:LK06_RS18760
uniprot id: A0A221P0U7
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1355015:LK06 RS06730
gene id: 1355015:LK06_RS06730
uniprot id: A0A221P915
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

1355015:LK06 RS23380
gene id: 1355015:LK06_RS23380
uniprot id: A0A221P300
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

1355015:LK06 RS17670
gene id: 1355015:LK06_RS17670
uniprot id: A0A221P0N7
names: Similarity
messages: Belongs to the Fur family.

1355015:LK06 RS06325
gene id: 1355015:LK06_RS06325
uniprot id: A0A221NVB2
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

1355015:LK06 RS09535
gene id: 1355015:LK06_RS09535
uniprot id: A0A221NWX8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1355015:LK06 RS04645
gene id: 1355015:LK06_RS04645
uniprot id: A0A221NUE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1355015:LK06 RS07020
gene id: 1355015:LK06_RS07020
uniprot id: A0A221P831
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1355015:LK06 RS01700
gene id: 1355015:LK06_RS01700
uniprot id: A0A221NT24
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1355015:LK06 RS10355
gene id: 1355015:LK06_RS10355
uniprot id: A0A221NXC2
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS00330
gene id: 1355015:LK06_RS00330
uniprot id: A0A221NSC8
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1355015:LK06 RS04705
gene id: 1355015:LK06_RS04705
uniprot id: A0A221NUG5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1355015:LK06 RS04995
gene id: 1355015:LK06_RS04995
uniprot id: A0A221NV17
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

1355015:LK06 RS04710
gene id: 1355015:LK06_RS04710
uniprot id: A0A221NUZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1355015:LK06 RS02130
gene id: 1355015:LK06_RS02130
uniprot id: A0A221NUJ5
names: Similarity
messages: Belongs to the DapA family.

1355015:LK06 RS03595
gene id: 1355015:LK06_RS03595
uniprot id: A0A221NU23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1355015:LK06 RS11355
gene id: 1355015:LK06_RS11355
uniprot id: A0A221NXS5
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS28570
gene id: 1355015:LK06_RS28570
uniprot id: A0A221P5X8
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

1355015:LK06 RS27520
gene id: 1355015:LK06_RS27520
uniprot id: A0A221P568
names: Similarity
messages: Belongs to the malate synthase family.

1355015:LK06 RS07145
gene id: 1355015:LK06_RS07145
uniprot id: A0A221NVM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1355015:LK06 RS07905
gene id: 1355015:LK06_RS07905
uniprot id: A0A221NW38
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1355015:LK06 RS14765
gene id: 1355015:LK06_RS14765
uniprot id: A0A221NZ47
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS12020
gene id: 1355015:LK06_RS12020
uniprot id: A0A221NXW5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS23240
gene id: 1355015:LK06_RS23240
uniprot id: A0A221P4A5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1355015:LK06 RS19690
gene id: 1355015:LK06_RS19690
uniprot id: A0A221P198
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1355015:LK06 RS17285
gene id: 1355015:LK06_RS17285
uniprot id: A0A221P091
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS03920
gene id: 1355015:LK06_RS03920
uniprot id: A0A221NU41
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS25335
gene id: 1355015:LK06_RS25335
uniprot id: A0A221P431
names: Subcellular Location Annotation
messages: Cytoplasm

1355015:LK06 RS19755
gene id: 1355015:LK06_RS19755
uniprot id: A0A221P1M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

1355015:LK06 RS18220
gene id: 1355015:LK06_RS18220
uniprot id: A0A221P0K8
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1355015:LK06 RS07055
gene id: 1355015:LK06_RS07055
uniprot id: A0A221NVK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1355015:LK06 RS15840
gene id: 1355015:LK06_RS15840
uniprot id: A0A221P042
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1355015:LK06 RS09530
gene id: 1355015:LK06_RS09530
uniprot id: A0A221NWN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1355015:LK06 RS26100
gene id: 1355015:LK06_RS26100
uniprot id: A0A221P4L4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1355015:LK06 RS23290
gene id: 1355015:LK06_RS23290
uniprot id: A0A221P378
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1355015:LK06 RS26125
gene id: 1355015:LK06_RS26125
uniprot id: A0A221P4G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1355015:LK06 RS20115
gene id: 1355015:LK06_RS20115
uniprot id: A0A221P1L0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1355015:LK06 RS13700
gene id: 1355015:LK06_RS13700
uniprot id: A0A221NYL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
messages: Cytoplasm

1355015:LK06 RS26060
gene id: 1355015:LK06_RS26060
uniprot id: A0A221P5L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

1355015:LK06 RS12475
gene id: 1355015:LK06_RS12475
uniprot id: A0A221NYC8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1355015:LK06 RS22770
gene id: 1355015:LK06_RS22770
uniprot id: A0A221P325
names: Subcellular Location Annotation
messages: Cell membrane

1355015:LK06 RS00480
gene id: 1355015:LK06_RS00480
uniprot id: A0A221NT17
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1355015:LK06 RS28160
gene id: 1355015:LK06_RS28160
uniprot id: A0A221P6M9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1355015:LK06 RS30690
gene id: 1355015:LK06_RS30690
uniprot id: A0A221P977
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1355015:LK06 RS29290
gene id: 1355015:LK06_RS29290
uniprot id: A0A221P5T6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

1355015:LK06 RS07285
gene id: 1355015:LK06_RS07285
uniprot id: A0A221NVL3
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1355015:LK06 RS19970
gene id: 1355015:LK06_RS19970
uniprot id: A0A221P1Y0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1355015:LK06 RS14920
gene id: 1355015:LK06_RS14920
uniprot id: A0A221NZG2
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1355015:LK06 RS00410
gene id: 1355015:LK06_RS00410
uniprot id: A0A221NTQ0
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1355015:LK06 RS28295
gene id: 1355015:LK06_RS28295
uniprot id: A0A221P5T7
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1355015:LK06 RS29300
gene id: 1355015:LK06_RS29300
uniprot id: A0A221P645
names: Similarity
messages: Belongs to the universal stress protein A family.

1355015:LK06 RS13355
gene id: 1355015:LK06_RS13355
uniprot id: A0A221NYZ2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1355015:LK06 RS23210
gene id: 1355015:LK06_RS23210
uniprot id: A0A221P8Q3
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1355015:LK06 RS24665
gene id: 1355015:LK06_RS24665
uniprot id: A0A221P3Y1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1355015:LK06 RS31375
gene id: 1355015:LK06_RS31375
uniprot id: A0A221P6V7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1355015:LK06 RS12150
gene id: 1355015:LK06_RS12150
uniprot id: A0A221NZA5
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1355015:LK06 RS28685
gene id: 1355015:LK06_RS28685
uniprot id: A0A221P5Z6
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1355015:LK06 RS30565
gene id: 1355015:LK06_RS30565
uniprot id: A0A221P7Q3
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1355015:LK06 RS11860
gene id: 1355015:LK06_RS11860
uniprot id: A0A221NXP5
names: Similarity
messages: Belongs to the PGI/PMI family.

1355015:LK06 RS26250
gene id: 1355015:LK06_RS26250
uniprot id: A0A221P508
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

1355015:LK06 RS14065
gene id: 1355015:LK06_RS14065
uniprot id: A0A221NZ15
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1355015:LK06 RS20645
gene id: 1355015:LK06_RS20645
uniprot id: A0A221P1R7
names: Subcellular Location Annotation
messages: Cell membrane

1355015:LK06 RS02960
gene id: 1355015:LK06_RS02960
uniprot id: A0A221NU87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1355015:LK06 RS08130
gene id: 1355015:LK06_RS08130
uniprot id: A0A221NW42
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1355015:LK06 RS13805
gene id: 1355015:LK06_RS13805
uniprot id: A0A221NYP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1355015:LK06 RS30575
gene id: 1355015:LK06_RS30575
uniprot id: A0A221P6V1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS26760
gene id: 1355015:LK06_RS26760
uniprot id: A0A221P4M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1355015:LK06 RS11465
gene id: 1355015:LK06_RS11465
uniprot id: A0A221NXQ1
names: Similarity
messages: Belongs to the XFP family.

1355015:LK06 RS06695
gene id: 1355015:LK06_RS06695
uniprot id: A0A221NWM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1355015:LK06 RS25990
gene id: 1355015:LK06_RS25990
uniprot id: A0A221P4T4
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1355015:LK06 RS23230
gene id: 1355015:LK06_RS23230
uniprot id: A0A221P394
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1355015:LK06 RS07180
gene id: 1355015:LK06_RS07180
uniprot id: A0A221NVT1
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS19945
gene id: 1355015:LK06_RS19945
uniprot id: A0A221P1H4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1355015:LK06 RS05705
gene id: 1355015:LK06_RS05705
uniprot id: A0A221NUY4
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

1355015:LK06 RS15715
gene id: 1355015:LK06_RS15715
uniprot id: A0A221P028
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1355015:LK06 RS13070
gene id: 1355015:LK06_RS13070
uniprot id: A0A221NYC6
names: Similarity
messages: Belongs to the UbiD family.

1355015:LK06 RS00045
gene id: 1355015:LK06_RS00045
uniprot id: A0A221NSH6
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS13525
gene id: 1355015:LK06_RS13525
uniprot id: A0A221NYL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1355015:LK06 RS12845
gene id: 1355015:LK06_RS12845
uniprot id: A0A221NY63
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1355015:LK06 RS13605
gene id: 1355015:LK06_RS13605
uniprot id: A0A221NYH7
names: Similarity
messages: Belongs to the Nth/MutY family.

1355015:LK06 RS17815
gene id: 1355015:LK06_RS17815
uniprot id: A0A221P122
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1355015:LK06 RS02340
gene id: 1355015:LK06_RS02340
uniprot id: A0A221NTI0
names: Similarity
messages: Belongs to the peptidase C40 family.

1355015:LK06 RS00375
gene id: 1355015:LK06_RS00375
uniprot id: A0A221NSF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS13820
gene id: 1355015:LK06_RS13820
uniprot id: A0A221NYR8
names: Similarity
messages: Belongs to the peptidase S13 family.

1355015:LK06 RS05230
gene id: 1355015:LK06_RS05230
uniprot id: A0A221NV91
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS12745
gene id: 1355015:LK06_RS12745
uniprot id: A0A221NZJ6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1355015:LK06 RS13930
gene id: 1355015:LK06_RS13930
uniprot id: A0A221P8A3
names: Subcellular Location Annotation
messages: Cell membrane

1355015:LK06 RS06665
gene id: 1355015:LK06_RS06665
uniprot id: A0A221NVF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1355015:LK06 RS16105
gene id: 1355015:LK06_RS16105
uniprot id: A0A221P142
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1355015:LK06 RS13060
gene id: 1355015:LK06_RS13060
uniprot id: A0A221NYE0
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS19790
gene id: 1355015:LK06_RS19790
uniprot id: A0A221P1T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. Tam family.
messages: Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
messages: Cytoplasm

1355015:LK06 RS15025
gene id: 1355015:LK06_RS15025
uniprot id: A0A221NZ82
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS23205
gene id: 1355015:LK06_RS23205
uniprot id: A0A221P328
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1355015:LK06 RS09870
gene id: 1355015:LK06_RS09870
uniprot id: A0A221NX30
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1355015:LK06 RS07260
gene id: 1355015:LK06_RS07260
uniprot id: A0A221NW59
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1355015:LK06 RS24880
gene id: 1355015:LK06_RS24880
uniprot id: A0A221P3W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1355015:LK06 RS07720
gene id: 1355015:LK06_RS07720
uniprot id: A0A221NVU3
names: Similarity
messages: Belongs to the PspA/IM30 family.

1355015:LK06 RS20535
gene id: 1355015:LK06_RS20535
uniprot id: A0A221P1X4
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1355015:LK06 RS06065
gene id: 1355015:LK06_RS06065
uniprot id: A0A221NVJ3
names: Similarity
messages: Belongs to the peptidase S8 family.

1355015:LK06 RS26695
gene id: 1355015:LK06_RS26695
uniprot id: A0A221P4R4
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS14540
gene id: 1355015:LK06_RS14540
uniprot id: A0A221NZ18
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1355015:LK06 RS24620
gene id: 1355015:LK06_RS24620
uniprot id: A0A221P400
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1355015:LK06 RS19660
gene id: 1355015:LK06_RS19660
uniprot id: A0A221P1K1
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS05285
gene id: 1355015:LK06_RS05285
uniprot id: A0A221NUS5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1355015:LK06 RS12990
gene id: 1355015:LK06_RS12990
uniprot id: A0A221NYV9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

1355015:LK06 RS04815
gene id: 1355015:LK06_RS04815
uniprot id: A0A221NUY7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1355015:LK06 RS03665
gene id: 1355015:LK06_RS03665
uniprot id: A0A221NUE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1355015:LK06 RS30240
gene id: 1355015:LK06_RS30240
uniprot id: A0A221P6Z3
names: Similarity
messages: Belongs to the universal stress protein A family.

1355015:LK06 RS15900
gene id: 1355015:LK06_RS15900
uniprot id: A0A221NZL8
names: Similarity
messages: Belongs to the ParB family.

1355015:LK06 RS12645
gene id: 1355015:LK06_RS12645
uniprot id: A0A221NYQ1
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS11420
gene id: 1355015:LK06_RS11420
uniprot id: A0A221NXV1
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1355015:LK06 RS18995
gene id: 1355015:LK06_RS18995
uniprot id: A0A221P0Z2
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1355015:LK06 RS31315
gene id: 1355015:LK06_RS31315
uniprot id: A0A221P7G0
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

1355015:LK06 RS28635
gene id: 1355015:LK06_RS28635
uniprot id: A0A221P5Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1355015:LK06 RS08290
gene id: 1355015:LK06_RS08290
uniprot id: A0A221NWA3
names: Similarity
messages: Belongs to the EfeM/EfeO family.

1355015:LK06 RS18695
gene id: 1355015:LK06_RS18695
uniprot id: A0A221P0T8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

1355015:LK06 RS26235
gene id: 1355015:LK06_RS26235
uniprot id: A0A221P5P3
names: Similarity
messages: Belongs to the asparagine synthetase family.

1355015:LK06 RS15020
gene id: 1355015:LK06_RS15020
uniprot id: A0A221NZP6
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS10350
gene id: 1355015:LK06_RS10350
uniprot id: A0A221NX51
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS08560
gene id: 1355015:LK06_RS08560
uniprot id: A0A221NWH1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1355015:LK06 RS01405
gene id: 1355015:LK06_RS01405
uniprot id: A0A221NTF8
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS09500
gene id: 1355015:LK06_RS09500
uniprot id: A0A221NWU8
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1355015:LK06 RS08325
gene id: 1355015:LK06_RS08325
uniprot id: A0A221NWL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS22360
gene id: 1355015:LK06_RS22360
uniprot id: A0A221P332
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1355015:LK06 RS15515
gene id: 1355015:LK06_RS15515
uniprot id: A0A221NZR3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1355015:LK06 RS07275
gene id: 1355015:LK06_RS07275
uniprot id: A0A221NVP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1355015:LK06 RS23590
gene id: 1355015:LK06_RS23590
uniprot id: A0A221P3A6
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS13780
gene id: 1355015:LK06_RS13780
uniprot id: A0A221NYX4
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1355015:LK06 RS23300
gene id: 1355015:LK06_RS23300
uniprot id: A0A221P3A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1355015:LK06 RS27060
gene id: 1355015:LK06_RS27060
uniprot id: A0A221P585
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1355015:LK06 RS10745
gene id: 1355015:LK06_RS10745
uniprot id: A0A221NX71
names: Similarity
messages: Belongs to the group II decarboxylase family.

1355015:LK06 RS12620
gene id: 1355015:LK06_RS12620
uniprot id: A0A221NY24
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS27075
gene id: 1355015:LK06_RS27075
uniprot id: A0A221P4T3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1355015:LK06 RS16620
gene id: 1355015:LK06_RS16620
uniprot id: A0A221P0G6
names: Subcellular Location Annotation
messages: Cell membrane

1355015:LK06 RS11955
gene id: 1355015:LK06_RS11955
uniprot id: A0A221NYC5
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1355015:LK06 RS14880
gene id: 1355015:LK06_RS14880
uniprot id: A0A221NZN1
names: Subcellular Location Annotation
messages: Cytoplasm

1355015:LK06 RS28845
gene id: 1355015:LK06_RS28845
uniprot id: A0A221P626
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

1355015:LK06 RS08685
gene id: 1355015:LK06_RS08685
uniprot id: A0A221NWE2
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS25415
gene id: 1355015:LK06_RS25415
uniprot id: A0A221P402
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS24045
gene id: 1355015:LK06_RS24045
uniprot id: A0A221P3N9
names: Similarity
messages: Belongs to the agmatine deiminase family.

1355015:LK06 RS12920
gene id: 1355015:LK06_RS12920
uniprot id: A0A221NYC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1355015:LK06 RS22040
gene id: 1355015:LK06_RS22040
uniprot id: A0A221P2M4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1355015:LK06 RS15330
gene id: 1355015:LK06_RS15330
uniprot id: A0A221NZF6
names: Similarity
messages: Belongs to the peptidase M18 family.

1355015:LK06 RS25060
gene id: 1355015:LK06_RS25060
uniprot id: A0A221P3S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS23570
gene id: 1355015:LK06_RS23570
uniprot id: A0A221P324
names: Subcellular Location Annotation
messages: Cytoplasm

1355015:LK06 RS18675
gene id: 1355015:LK06_RS18675
uniprot id: A0A221P265
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1355015:LK06 RS21645
gene id: 1355015:LK06_RS21645
uniprot id: A0A221P2F1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1355015:LK06 RS08800
gene id: 1355015:LK06_RS08800
uniprot id: A0A221NWL5
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS04280
gene id: 1355015:LK06_RS04280
uniprot id: A0A221NU86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1355015:LK06 RS06620
gene id: 1355015:LK06_RS06620
uniprot id: A0A221NVA2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1355015:LK06 RS26545
gene id: 1355015:LK06_RS26545
uniprot id: A0A221P4G3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1355015:LK06 RS11300
gene id: 1355015:LK06_RS11300
uniprot id: A0A221NYX7
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1355015:LK06 RS07770
gene id: 1355015:LK06_RS07770
uniprot id: A0A221NWF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1355015:LK06 RS12635
gene id: 1355015:LK06_RS12635
uniprot id: A0A221NYN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1355015:LK06 RS13905
gene id: 1355015:LK06_RS13905
uniprot id: A0A221NYZ4
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

1355015:LK06 RS24180
gene id: 1355015:LK06_RS24180
uniprot id: A0A221P3R6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1355015:LK06 RS06625
gene id: 1355015:LK06_RS06625
uniprot id: A0A221NVH9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1355015:LK06 RS09665
gene id: 1355015:LK06_RS09665
uniprot id: A0A221NX10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1355015:LK06 RS16250
gene id: 1355015:LK06_RS16250
uniprot id: A0A221P0E5
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS17205
gene id: 1355015:LK06_RS17205
uniprot id: A0A221P0P1
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1355015:LK06 RS15175
gene id: 1355015:LK06_RS15175
uniprot id: A0A221NZE2
names: Similarity
messages: Belongs to the CdaR family.

1355015:LK06 RS31725
gene id: 1355015:LK06_RS31725
uniprot id: A0A221P6V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS06025
gene id: 1355015:LK06_RS06025
uniprot id: A0A221NUZ4
names: Similarity
messages: Belongs to the peptidase U62 family.

1355015:LK06 RS24450
gene id: 1355015:LK06_RS24450
uniprot id: A0A221P3G4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1355015:LK06 RS31170
gene id: 1355015:LK06_RS31170
uniprot id: A0A221P700
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1355015:LK06 RS13690
gene id: 1355015:LK06_RS13690
uniprot id: A0A221NYM3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS32065
gene id: 1355015:LK06_RS32065
uniprot id: A0A221P8D5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1355015:LK06 RS05035
gene id: 1355015:LK06_RS05035
uniprot id: A0A221NUI5
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

1355015:LK06 RS26645
gene id: 1355015:LK06_RS26645
uniprot id: A0A221P4K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1355015:LK06 RS18570
gene id: 1355015:LK06_RS18570
uniprot id: A0A221P8X0
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS09350
gene id: 1355015:LK06_RS09350
uniprot id: A0A221NWV0
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS11855
gene id: 1355015:LK06_RS11855
uniprot id: A0A221NY20
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1355015:LK06 RS24915
gene id: 1355015:LK06_RS24915
uniprot id: A0A221P452
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1355015:LK06 RS32055
gene id: 1355015:LK06_RS32055
uniprot id: A0A221P7E5
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

1355015:LK06 RS10760
gene id: 1355015:LK06_RS10760
uniprot id: A0A221NYN3
names: Similarity
messages: Belongs to the IucA/IucC family.

1355015:LK06 RS09495
gene id: 1355015:LK06_RS09495
uniprot id: A0A221NWN8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1355015:LK06 RS12060
gene id: 1355015:LK06_RS12060
uniprot id: A0A221NXV6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1355015:LK06 RS25150
gene id: 1355015:LK06_RS25150
uniprot id: A0A221P4H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1355015:LK06 RS18435
gene id: 1355015:LK06_RS18435
uniprot id: A0A221P226
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

1355015:LK06 RS01285
gene id: 1355015:LK06_RS01285
uniprot id: A0A221NSV2
names: Similarity
messages: Belongs to the peptidase C59 family.

1355015:LK06 RS25070
gene id: 1355015:LK06_RS25070
uniprot id: A0A221P551
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1355015:LK06 RS05115
gene id: 1355015:LK06_RS05115
uniprot id: A0A221NV72
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1355015:LK06 RS04695
gene id: 1355015:LK06_RS04695
uniprot id: A0A221NVP7
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1355015:LK06 RS06975
gene id: 1355015:LK06_RS06975
uniprot id: A0A221NVJ4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1355015:LK06 RS31275
gene id: 1355015:LK06_RS31275
uniprot id: A0A221P6P1
names: Similarity
messages: Belongs to the HypD family.

1355015:LK06 RS24260
gene id: 1355015:LK06_RS24260
uniprot id: A0A221P3L4
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1355015:LK06 RS12630
gene id: 1355015:LK06_RS12630
uniprot id: A0A221NZH7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS08145
gene id: 1355015:LK06_RS08145
uniprot id: A0A221NXE5
names: Caution
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS30885
gene id: 1355015:LK06_RS30885
uniprot id: A0A221P787
names: Similarity
messages: Belongs to the universal stress protein A family.

1355015:LK06 RS15375
gene id: 1355015:LK06_RS15375
uniprot id: A0A221NZD5
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1355015:LK06 RS28575
gene id: 1355015:LK06_RS28575
uniprot id: A0A221P5K8
names: Similarity
messages: Belongs to the DDAH family.

1355015:LK06 RS08095
gene id: 1355015:LK06_RS08095
uniprot id: A0A221NXD4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1355015:LK06 RS12250
gene id: 1355015:LK06_RS12250
uniprot id: A0A221NY72
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1355015:LK06 RS24440
gene id: 1355015:LK06_RS24440
uniprot id: A0A221P3J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1355015:LK06 RS27580
gene id: 1355015:LK06_RS27580
uniprot id: A0A221P576
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS32010
gene id: 1355015:LK06_RS32010
uniprot id: A0A221P6Z4
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1355015:LK06 RS10930
gene id: 1355015:LK06_RS10930
uniprot id: A0A221NX99
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1355015:LK06 RS02275
gene id: 1355015:LK06_RS02275
uniprot id: A0A221NTB4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1355015:LK06 RS21085
gene id: 1355015:LK06_RS21085
uniprot id: A0A221P1Z3
names: Subunit
messages: Homodimer.

1355015:LK06 RS15875
gene id: 1355015:LK06_RS15875
uniprot id: A0A221NZK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1355015:LK06 RS06545
gene id: 1355015:LK06_RS06545
uniprot id: A0A221NV84
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS03945
gene id: 1355015:LK06_RS03945
uniprot id: A0A221NU49
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1355015:LK06 RS20025
gene id: 1355015:LK06_RS20025
uniprot id: A0A221P1Z0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1355015:LK06 RS18665
gene id: 1355015:LK06_RS18665
uniprot id: A0A221P0S6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1355015:LK06 RS00910
gene id: 1355015:LK06_RS00910
uniprot id: A0A221NSL9
names: Similarity
messages: Belongs to the peptidase S1 family.

1355015:LK06 RS06480
gene id: 1355015:LK06_RS06480
uniprot id: A0A221NVU1
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1355015:LK06 RS01170
gene id: 1355015:LK06_RS01170
uniprot id: A0A221NST3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1355015:LK06 RS02365
gene id: 1355015:LK06_RS02365
uniprot id: A0A221NTY1
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1355015:LK06 RS14085
gene id: 1355015:LK06_RS14085
uniprot id: A0A221NYU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Membrane

1355015:LK06 RS20330
gene id: 1355015:LK06_RS20330
uniprot id: A0A221P1V5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1355015:LK06 RS30030
gene id: 1355015:LK06_RS30030
uniprot id: A0A221P6B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmG family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.

1355015:LK06 RS12955
gene id: 1355015:LK06_RS12955
uniprot id: A0A221NYK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1355015:LK06 RS24030
gene id: 1355015:LK06_RS24030
uniprot id: A0A221P3C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1355015:LK06 RS30965
gene id: 1355015:LK06_RS30965
uniprot id: A0A221P6J8
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

1355015:LK06 RS19625
gene id: 1355015:LK06_RS19625
uniprot id: A0A221P187
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS10705
gene id: 1355015:LK06_RS10705
uniprot id: A0A221P887
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1355015:LK06 RS14355
gene id: 1355015:LK06_RS14355
uniprot id: A0A221NZF8
names: Subcellular Location Annotation
messages: Cell membrane

1355015:LK06 RS23640
gene id: 1355015:LK06_RS23640
uniprot id: A0A221P3H2
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1355015:LK06 RS01770
gene id: 1355015:LK06_RS01770
uniprot id: A0A221NT51
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1355015:LK06 RS09995
gene id: 1355015:LK06_RS09995
uniprot id: A0A221NWV7
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1355015:LK06 RS07790
gene id: 1355015:LK06_RS07790
uniprot id: A0A221NVY7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1355015:LK06 RS12510
gene id: 1355015:LK06_RS12510
uniprot id: A0A221NY58
names: Similarity
messages: Belongs to the UPF0336 family.

1355015:LK06 RS28935
gene id: 1355015:LK06_RS28935
uniprot id: A0A221P5J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS12945
gene id: 1355015:LK06_RS12945
uniprot id: A0A221NYK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1355015:LK06 RS05985
gene id: 1355015:LK06_RS05985
uniprot id: A0A221NV92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1355015:LK06 RS16235
gene id: 1355015:LK06_RS16235
uniprot id: A0A221P159
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1355015:LK06 RS31745
gene id: 1355015:LK06_RS31745
uniprot id: A0A221P6X0
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1355015:LK06 RS13765
gene id: 1355015:LK06_RS13765
uniprot id: A0A221NYQ9
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS00455
gene id: 1355015:LK06_RS00455
uniprot id: A0A221NSE7
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1355015:LK06 RS16245
gene id: 1355015:LK06_RS16245
uniprot id: A0A221NZT1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

1355015:LK06 RS25085
gene id: 1355015:LK06_RS25085
uniprot id: A0A221P3Z5
names: Subcellular Location Annotation
messages: Cell membrane

1355015:LK06 RS06500
gene id: 1355015:LK06_RS06500
uniprot id: A0A221NVB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS29395
gene id: 1355015:LK06_RS29395
uniprot id: A0A221P6L0
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1355015:LK06 RS22495
gene id: 1355015:LK06_RS22495
uniprot id: A0A221P2L3
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1355015:LK06 RS01940
gene id: 1355015:LK06_RS01940
uniprot id: A0A221NTD5
names: Similarity
messages: Belongs to the DNA photolyase family.

1355015:LK06 RS02965
gene id: 1355015:LK06_RS02965
uniprot id: A0A221NTN2
names: Similarity
messages: Belongs to the IMPACT family.

1355015:LK06 RS24360
gene id: 1355015:LK06_RS24360
uniprot id: A0A221P4T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1355015:LK06 RS15880
gene id: 1355015:LK06_RS15880
uniprot id: A0A221NZX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1355015:LK06 RS24080
gene id: 1355015:LK06_RS24080
uniprot id: A0A221P3D4
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1355015:LK06 RS11160
gene id: 1355015:LK06_RS11160
uniprot id: A0A221NXF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1355015:LK06 RS30270
gene id: 1355015:LK06_RS30270
uniprot id: A0A221P6K1
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS20085
gene id: 1355015:LK06_RS20085
uniprot id: A0A221P202
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1355015:LK06 RS11905
gene id: 1355015:LK06_RS11905
uniprot id: A0A221NXU3
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

1355015:LK06 RS09875
gene id: 1355015:LK06_RS09875
uniprot id: A0A221NY92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1355015:LK06 RS15365
gene id: 1355015:LK06_RS15365
uniprot id: A0A221NZW6
names: Similarity
messages: Belongs to the peptidase S11 family.

1355015:LK06 RS23740
gene id: 1355015:LK06_RS23740
uniprot id: A0A221P3C3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS30145
gene id: 1355015:LK06_RS30145
uniprot id: A0A221P6Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS02875
gene id: 1355015:LK06_RS02875
uniprot id: A0A221NU22
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1355015:LK06 RS28710
gene id: 1355015:LK06_RS28710
uniprot id: A0A221P5R0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1355015:LK06 RS04060
gene id: 1355015:LK06_RS04060
uniprot id: A0A221NU29
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1355015:LK06 RS02380
gene id: 1355015:LK06_RS02380
uniprot id: A0A221NTF9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS10005
gene id: 1355015:LK06_RS10005
uniprot id: A0A221NYB6
names: Similarity
messages: Belongs to the peptidase M1 family.

1355015:LK06 RS29525
gene id: 1355015:LK06_RS29525
uniprot id: A0A221P5T9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1355015:LK06 RS29715
gene id: 1355015:LK06_RS29715
uniprot id: A0A221P602
names: Similarity
messages: Belongs to the UPF0047 family.

1355015:LK06 RS00580
gene id: 1355015:LK06_RS00580
uniprot id: A0A221NSG8
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

1355015:LK06 RS09155
gene id: 1355015:LK06_RS09155
uniprot id: A0A221NWL6
names: Similarity
messages: Belongs to the FGGY kinase family.

1355015:LK06 RS12260
gene id: 1355015:LK06_RS12260
uniprot id: A0A221NYH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1355015:LK06 RS10680
gene id: 1355015:LK06_RS10680
uniprot id: A0A221NX62
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1355015:LK06 RS14020
gene id: 1355015:LK06_RS14020
uniprot id: A0A221NYT5
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1355015:LK06 RS06100
gene id: 1355015:LK06_RS06100
uniprot id: A0A221NV14
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1355015:LK06 RS12900
gene id: 1355015:LK06_RS12900
uniprot id: A0A221NY73
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS30500
gene id: 1355015:LK06_RS30500
uniprot id: A0A221P7P3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1355015:LK06 RS04335
gene id: 1355015:LK06_RS04335
uniprot id: A0A221NUD5
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1355015:LK06 RS03985
gene id: 1355015:LK06_RS03985
uniprot id: A0A221NU35
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1355015:LK06 RS14410
gene id: 1355015:LK06_RS14410
uniprot id: A0A221NYY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS21895
gene id: 1355015:LK06_RS21895
uniprot id: A0A221P2I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS24815
gene id: 1355015:LK06_RS24815
uniprot id: A0A221P4B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS11945
gene id: 1355015:LK06_RS11945
uniprot id: A0A221NYB0
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1355015:LK06 RS23465
gene id: 1355015:LK06_RS23465
uniprot id: A0A221P3L1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1355015:LK06 RS02150
gene id: 1355015:LK06_RS02150
uniprot id: A0A221NTA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS04115
gene id: 1355015:LK06_RS04115
uniprot id: A0A221NU38
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1355015:LK06 RS29590
gene id: 1355015:LK06_RS29590
uniprot id: A0A221P9A5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1355015:LK06 RS19990
gene id: 1355015:LK06_RS19990
uniprot id: A0A221P1I9
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS06745
gene id: 1355015:LK06_RS06745
uniprot id: A0A221NVC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1355015:LK06 RS07935
gene id: 1355015:LK06_RS07935
uniprot id: A0A221NWF3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1355015:LK06 RS13810
gene id: 1355015:LK06_RS13810
uniprot id: A0A221NZ78
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1355015:LK06 RS04480
gene id: 1355015:LK06_RS04480
uniprot id: A0A221NUJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1355015:LK06 RS19985
gene id: 1355015:LK06_RS19985
uniprot id: A0A221P1E7
names: Similarity
messages: Belongs to the CFA/CMAS family.

1355015:LK06 RS12425
gene id: 1355015:LK06_RS12425
uniprot id: A0A221NYK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1355015:LK06 RS10270
gene id: 1355015:LK06_RS10270
uniprot id: A0A221NX35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1355015:LK06 RS12655
gene id: 1355015:LK06_RS12655
uniprot id: A0A221NY96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1355015:LK06 RS25135
gene id: 1355015:LK06_RS25135
uniprot id: A0A221P562
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS12200
gene id: 1355015:LK06_RS12200
uniprot id: A0A221NZB4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1355015:LK06 RS12285
gene id: 1355015:LK06_RS12285
uniprot id: A0A221NY14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1355015:LK06 RS21285
gene id: 1355015:LK06_RS21285
uniprot id: A0A221P250
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS04350
gene id: 1355015:LK06_RS04350
uniprot id: A0A221NUH9
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS30355
gene id: 1355015:LK06_RS30355
uniprot id: A0A221P6F1
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1355015:LK06 RS15185
gene id: 1355015:LK06_RS15185
uniprot id: A0A221NZ76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1355015:LK06 RS15625
gene id: 1355015:LK06_RS15625
uniprot id: A0A221NZS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

1355015:LK06 RS30875
gene id: 1355015:LK06_RS30875
uniprot id: A0A221P701
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

1355015:LK06 RS03325
gene id: 1355015:LK06_RS03325
uniprot id: A0A221NV25
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1355015:LK06 RS05270
gene id: 1355015:LK06_RS05270
uniprot id: A0A221NUV7
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS12230
gene id: 1355015:LK06_RS12230
uniprot id: A0A221NY08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1355015:LK06 RS10610
gene id: 1355015:LK06_RS10610
uniprot id: A0A221NXG3
names: Similarity
messages: Belongs to the citrate synthase family.

1355015:LK06 RS06130
gene id: 1355015:LK06_RS06130
uniprot id: A0A221NV54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1355015:LK06 RS18795
gene id: 1355015:LK06_RS18795
uniprot id: A0A221P283
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1355015:LK06 RS31390
gene id: 1355015:LK06_RS31390
uniprot id: A0A221P7G5
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

1355015:LK06 RS12455
gene id: 1355015:LK06_RS12455
uniprot id: A0A221NY46
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1355015:LK06 RS09180
gene id: 1355015:LK06_RS09180
uniprot id: A0A221NXX8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1355015:LK06 RS31265
gene id: 1355015:LK06_RS31265
uniprot id: A0A221P6N5
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

1355015:LK06 RS10755
gene id: 1355015:LK06_RS10755
uniprot id: A0A221NXH0
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

1355015:LK06 RS06555
gene id: 1355015:LK06_RS06555
uniprot id: A0A221NVD0
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1355015:LK06 RS01230
gene id: 1355015:LK06_RS01230
uniprot id: A0A221NSV6
names: Similarity
messages: In the N-terminal section; belongs to the cytochrome P450 family.

1355015:LK06 RS17165
gene id: 1355015:LK06_RS17165
uniprot id: A0A221P097
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1355015:LK06 RS00145
gene id: 1355015:LK06_RS00145
uniprot id: A0A221NSC3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1355015:LK06 RS30455
gene id: 1355015:LK06_RS30455
uniprot id: A0A221P722
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1355015:LK06 RS07655
gene id: 1355015:LK06_RS07655
uniprot id: A0A221NWD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1355015:LK06 RS17045
gene id: 1355015:LK06_RS17045
uniprot id: A0A221P0E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1355015:LK06 RS12185
gene id: 1355015:LK06_RS12185
uniprot id: A0A221NY80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1355015:LK06 RS06230
gene id: 1355015:LK06_RS06230
uniprot id: A0A221NWE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

1355015:LK06 RS00690
gene id: 1355015:LK06_RS00690
uniprot id: A0A221P8M8
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1355015:LK06 RS04250
gene id: 1355015:LK06_RS04250
uniprot id: A0A221NUC7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1355015:LK06 RS03250
gene id: 1355015:LK06_RS03250
uniprot id: A0A221NTR2
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS02255
gene id: 1355015:LK06_RS02255
uniprot id: A0A221NTC1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1355015:LK06 RS07480
gene id: 1355015:LK06_RS07480
uniprot id: A0A221NVS9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1355015:LK06 RS02135
gene id: 1355015:LK06_RS02135
uniprot id: A0A221NTN5
names: Similarity
messages: Belongs to the proline racemase family.

1355015:LK06 RS16970
gene id: 1355015:LK06_RS16970
uniprot id: A0A221P0D2
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1355015:LK06 RS27965
gene id: 1355015:LK06_RS27965
uniprot id: A0A221P5L2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1355015:LK06 RS18205
gene id: 1355015:LK06_RS18205
uniprot id: A0A221P141
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1355015:LK06 RS09305
gene id: 1355015:LK06_RS09305
uniprot id: A0A221NX45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS18345
gene id: 1355015:LK06_RS18345
uniprot id: A0A221P1A2
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS30325
gene id: 1355015:LK06_RS30325
uniprot id: A0A221P6L3
names: Similarity
messages: Belongs to the UPF0166 family.

1355015:LK06 RS02465
gene id: 1355015:LK06_RS02465
uniprot id: A0A221NTE6
names: Similarity
messages: Belongs to the cytochrome P450 family.

1355015:LK06 RS25115
gene id: 1355015:LK06_RS25115
uniprot id: A0A221P453
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1355015:LK06 RS14600
gene id: 1355015:LK06_RS14600
uniprot id: A0A221NZ34
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS11865
gene id: 1355015:LK06_RS11865
uniprot id: A0A221NY02
names: Similarity
messages: Belongs to the UPF0434 family.

1355015:LK06 RS10175
gene id: 1355015:LK06_RS10175
uniprot id: A0A221NWY5
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1355015:LK06 RS00020
gene id: 1355015:LK06_RS00020
uniprot id: A0A221NSA1
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1355015:LK06 RS24885
gene id: 1355015:LK06_RS24885
uniprot id: A0A221P4D1
names: Similarity
messages: Belongs to the peptidase M16 family.

1355015:LK06 RS06490
gene id: 1355015:LK06_RS06490
uniprot id: A0A221NVE6
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

1355015:LK06 RS12135
gene id: 1355015:LK06_RS12135
uniprot id: A0A221NY67
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1355015:LK06 RS09245
gene id: 1355015:LK06_RS09245
uniprot id: A0A221NWN1
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1355015:LK06 RS05980
gene id: 1355015:LK06_RS05980
uniprot id: A0A221NV29
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1355015:LK06 RS29705
gene id: 1355015:LK06_RS29705
uniprot id: A0A221P650
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1355015:LK06 RS05275
gene id: 1355015:LK06_RS05275
uniprot id: A0A221NVZ5
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS29800
gene id: 1355015:LK06_RS29800
uniprot id: A0A221P6F4
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS09440
gene id: 1355015:LK06_RS09440
uniprot id: A0A221NWM8
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS25440
gene id: 1355015:LK06_RS25440
uniprot id: A0A221P497
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS11580
gene id: 1355015:LK06_RS11580
uniprot id: A0A221NXN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1355015:LK06 RS03650
gene id: 1355015:LK06_RS03650
uniprot id: A0A221NTW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

1355015:LK06 RS11105
gene id: 1355015:LK06_RS11105
uniprot id: A0A221NXQ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1355015:LK06 RS11915
gene id: 1355015:LK06_RS11915
uniprot id: A0A221NXQ5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Bifunctional enzyme that catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2-dependent reduction of dehydro-F420-0 to form F420-0.
messages: Binds 2 divalent metal cations per subunit. The ions could be magnesium and/or manganese.
messages: In the N-terminal section; belongs to the CofE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monovalent cation. The ion could be potassium.

1355015:LK06 RS28240
gene id: 1355015:LK06_RS28240
uniprot id: A0A221P618
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1355015:LK06 RS32080
gene id: 1355015:LK06_RS32080
uniprot id: A0A221P7R6
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1355015:LK06 RS09910
gene id: 1355015:LK06_RS09910
uniprot id: A0A221NX49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1355015:LK06 RS17265
gene id: 1355015:LK06_RS17265
uniprot id: A0A221P0H9
names: Function
names: Similarity
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1355015:LK06 RS30855
gene id: 1355015:LK06_RS30855
uniprot id: A0A221P6D7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1355015:LK06 RS21355
gene id: 1355015:LK06_RS21355
uniprot id: A0A221P234
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1355015:LK06 RS14760
gene id: 1355015:LK06_RS14760
uniprot id: A0A221NZL3
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1355015:LK06 RS03015
gene id: 1355015:LK06_RS03015
uniprot id: A0A221NU95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS24990
gene id: 1355015:LK06_RS24990
uniprot id: A0A221P3R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1355015:LK06 RS06275
gene id: 1355015:LK06_RS06275
uniprot id: A0A221NV78
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1355015:LK06 RS05415
gene id: 1355015:LK06_RS05415
uniprot id: A0A221NV87
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1355015:LK06 RS03950
gene id: 1355015:LK06_RS03950
uniprot id: A0A221NUA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1355015:LK06 RS12195
gene id: 1355015:LK06_RS12195
uniprot id: A0A221NY62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1355015:LK06 RS21990
gene id: 1355015:LK06_RS21990
uniprot id: A0A221P2N6
names: Similarity
messages: Belongs to the LOG family.

1355015:LK06 RS20490
gene id: 1355015:LK06_RS20490
uniprot id: A0A221P1M9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS08860
gene id: 1355015:LK06_RS08860
uniprot id: A0A221NWY1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1355015:LK06 RS31260
gene id: 1355015:LK06_RS31260
uniprot id: A0A221P7E7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1355015:LK06 RS07070
gene id: 1355015:LK06_RS07070
uniprot id: A0A221NVQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1355015:LK06 RS20260
gene id: 1355015:LK06_RS20260
uniprot id: A0A221P8L2
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS21030
gene id: 1355015:LK06_RS21030
uniprot id: A0A221P203
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

1355015:LK06 RS05765
gene id: 1355015:LK06_RS05765
uniprot id: A0A221NUZ3
names: Similarity
messages: Belongs to the TlyA family.

1355015:LK06 RS02185
gene id: 1355015:LK06_RS02185
uniprot id: A0A221NTP3
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

1355015:LK06 RS07270
gene id: 1355015:LK06_RS07270
uniprot id: A0A221NVS5
names: Similarity
messages: Belongs to the YggT family.

1355015:LK06 RS21705
gene id: 1355015:LK06_RS21705
uniprot id: A0A221P2F9
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1355015:LK06 RS23365
gene id: 1355015:LK06_RS23365
uniprot id: A0A221P3I6
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1355015:LK06 RS18710
gene id: 1355015:LK06_RS18710
uniprot id: A0A221P0Y9
names: Similarity
messages: Belongs to the UPF0309 family.

1355015:LK06 RS26300
gene id: 1355015:LK06_RS26300
uniprot id: A0A221P523
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

1355015:LK06 RS21280
gene id: 1355015:LK06_RS21280
uniprot id: A0A221P276
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS30705
gene id: 1355015:LK06_RS30705
uniprot id: A0A221P6J7
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS06180
gene id: 1355015:LK06_RS06180
uniprot id: A0A221NVL4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1355015:LK06 RS17555
gene id: 1355015:LK06_RS17555
uniprot id: A0A221P9S6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1355015:LK06 RS02070
gene id: 1355015:LK06_RS02070
uniprot id: A0A221NUI4
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1355015:LK06 RS13395
gene id: 1355015:LK06_RS13395
uniprot id: A0A221NYR6
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1355015:LK06 RS05760
gene id: 1355015:LK06_RS05760
uniprot id: A0A221NV21
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS08430
gene id: 1355015:LK06_RS08430
uniprot id: A0A221NWB9
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1355015:LK06 RS23625
gene id: 1355015:LK06_RS23625
uniprot id: A0A221P357
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

1355015:LK06 RS26070
gene id: 1355015:LK06_RS26070
uniprot id: A0A221P4F4
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS17245
gene id: 1355015:LK06_RS17245
uniprot id: A0A221P0A7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1355015:LK06 RS21940
gene id: 1355015:LK06_RS21940
uniprot id: A0A221P2W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

1355015:LK06 RS31475
gene id: 1355015:LK06_RS31475
uniprot id: A0A221P6Y5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS07855
gene id: 1355015:LK06_RS07855
uniprot id: A0A221NVZ9
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS23400
gene id: 1355015:LK06_RS23400
uniprot id: A0A221P2Z6
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS18285
gene id: 1355015:LK06_RS18285
uniprot id: A0A221P189
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1355015:LK06 RS05945
gene id: 1355015:LK06_RS05945
uniprot id: A0A221NW95
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1355015:LK06 RS34785
gene id: 1355015:LK06_RS34785
uniprot id: A0A221P730
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1355015:LK06 RS12925
gene id: 1355015:LK06_RS12925
uniprot id: A0A221NYU8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1355015:LK06 RS21790
gene id: 1355015:LK06_RS21790
uniprot id: A0A221P2V3
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1355015:LK06 RS24020
gene id: 1355015:LK06_RS24020
uniprot id: A0A221P3C0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1355015:LK06 RS12170
gene id: 1355015:LK06_RS12170
uniprot id: A0A221NXX6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1355015:LK06 RS05680
gene id: 1355015:LK06_RS05680
uniprot id: A0A221NUZ0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1355015:LK06 RS04260
gene id: 1355015:LK06_RS04260
uniprot id: A0A221NUP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1355015:LK06 RS12915
gene id: 1355015:LK06_RS12915
uniprot id: A0A221NYS7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1355015:LK06 RS08090
gene id: 1355015:LK06_RS08090
uniprot id: A0A221NW98
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1355015:LK06 RS13315
gene id: 1355015:LK06_RS13315
uniprot id: A0A221NYI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

1355015:LK06 RS20730
gene id: 1355015:LK06_RS20730
uniprot id: A0A221P208
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1355015:LK06 RS30335
gene id: 1355015:LK06_RS30335
uniprot id: A0A221P6N1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS13675
gene id: 1355015:LK06_RS13675
uniprot id: A0A221NYV5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1355015:LK06 RS19240
gene id: 1355015:LK06_RS19240
uniprot id: A0A221P131
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1355015:LK06 RS25140
gene id: 1355015:LK06_RS25140
uniprot id: A0A221P4E0
names: Similarity
messages: Belongs to the RelA/SpoT family.

1355015:LK06 RS13800
gene id: 1355015:LK06_RS13800
uniprot id: A0A221NZ62
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1355015:LK06 RS23430
gene id: 1355015:LK06_RS23430
uniprot id: A0A221P310
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1355015:LK06 RS09855
gene id: 1355015:LK06_RS09855
uniprot id: A0A221NWX2
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS23860
gene id: 1355015:LK06_RS23860
uniprot id: A0A221P383
names: Similarity
messages: Belongs to the LOG family.

1355015:LK06 RS08345
gene id: 1355015:LK06_RS08345
uniprot id: A0A221P7R8
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS12235
gene id: 1355015:LK06_RS12235
uniprot id: A0A221NY89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1355015:LK06 RS23265
gene id: 1355015:LK06_RS23265
uniprot id: A0A221P2X9
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS29230
gene id: 1355015:LK06_RS29230
uniprot id: A0A221P5P1
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS07155
gene id: 1355015:LK06_RS07155
uniprot id: A0A221NVI6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS17120
gene id: 1355015:LK06_RS17120
uniprot id: A0A221P0F4
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS23780
gene id: 1355015:LK06_RS23780
uniprot id: A0A221P3Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS31765
gene id: 1355015:LK06_RS31765
uniprot id: A0A221P888
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1355015:LK06 RS06940
gene id: 1355015:LK06_RS06940
uniprot id: A0A221NVI2
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

1355015:LK06 RS11840
gene id: 1355015:LK06_RS11840
uniprot id: A0A221NXV8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1355015:LK06 RS06035
gene id: 1355015:LK06_RS06035
uniprot id: A0A221NV38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1355015:LK06 RS15910
gene id: 1355015:LK06_RS15910
uniprot id: A0A221NZK9
names: Similarity
messages: Belongs to the thioredoxin family.

1355015:LK06 RS04845
gene id: 1355015:LK06_RS04845
uniprot id: A0A221NUL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS30510
gene id: 1355015:LK06_RS30510
uniprot id: A0A221P6H3
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS20950
gene id: 1355015:LK06_RS20950
uniprot id: A0A221P8Q6
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS21890
gene id: 1355015:LK06_RS21890
uniprot id: A0A221P2V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS05095
gene id: 1355015:LK06_RS05095
uniprot id: A0A221NUT0
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1355015:LK06 RS13825
gene id: 1355015:LK06_RS13825
uniprot id: A0A221P8G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1355015:LK06 RS18295
gene id: 1355015:LK06_RS18295
uniprot id: A0A221P0S2
names: Subcellular Location Annotation
messages: Cytoplasm

1355015:LK06 RS02245
gene id: 1355015:LK06_RS02245
uniprot id: A0A221NTC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

1355015:LK06 RS04565
gene id: 1355015:LK06_RS04565
uniprot id: A0A221NUH6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1355015:LK06 RS08700
gene id: 1355015:LK06_RS08700
uniprot id: A0A221NWW4
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1355015:LK06 RS25165
gene id: 1355015:LK06_RS25165
uniprot id: A0A221P404
names: Similarity
messages: Belongs to the alkaline phosphatase family.

1355015:LK06 RS22010
gene id: 1355015:LK06_RS22010
uniprot id: A0A221P2Z8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1355015:LK06 RS29595
gene id: 1355015:LK06_RS29595
uniprot id: A0A221P6P3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1355015:LK06 RS00930
gene id: 1355015:LK06_RS00930
uniprot id: A0A221NSP6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1355015:LK06 RS26570
gene id: 1355015:LK06_RS26570
uniprot id: A0A221P4Z5
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS00840
gene id: 1355015:LK06_RS00840
uniprot id: A0A221P7G1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

1355015:LK06 RS17870
gene id: 1355015:LK06_RS17870
uniprot id: A0A221P0I2
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1355015:LK06 RS02075
gene id: 1355015:LK06_RS02075
uniprot id: A0A221NTM9
names: Similarity
messages: Belongs to the cytochrome P450 family.

1355015:LK06 RS13850
gene id: 1355015:LK06_RS13850
uniprot id: A0A221P013
names: Similarity
messages: Belongs to the group II decarboxylase family.

1355015:LK06 RS12305
gene id: 1355015:LK06_RS12305
uniprot id: A0A221NZD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1355015:LK06 RS22450
gene id: 1355015:LK06_RS22450
uniprot id: A0A221P2N1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS31540
gene id: 1355015:LK06_RS31540
uniprot id: A0A221P6Z5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1355015:LK06 RS20280
gene id: 1355015:LK06_RS20280
uniprot id: A0A221P228
names: Similarity
messages: Belongs to the peptidase C40 family.

1355015:LK06 RS17835
gene id: 1355015:LK06_RS17835
uniprot id: A0A221P0R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1355015:LK06 RS05620
gene id: 1355015:LK06_RS05620
uniprot id: A0A221NUX7
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1355015:LK06 RS07135
gene id: 1355015:LK06_RS07135
uniprot id: A0A221NWV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Involved in both the histidine and tryptophan biosynthetic pathways.

1355015:LK06 RS31140
gene id: 1355015:LK06_RS31140
uniprot id: A0A221P740
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1355015:LK06 RS12225
gene id: 1355015:LK06_RS12225
uniprot id: A0A221NY29
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1355015:LK06 RS27795
gene id: 1355015:LK06_RS27795
uniprot id: A0A221P5U0
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1355015:LK06 RS24425
gene id: 1355015:LK06_RS24425
uniprot id: A0A221P443
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates guanosine-37 in various tRNAs.

1355015:LK06 RS30915
gene id: 1355015:LK06_RS30915
uniprot id: A0A221P6E6
names: Similarity
messages: Belongs to the peptidase M1 family.

1355015:LK06 RS16095
gene id: 1355015:LK06_RS16095
uniprot id: A0A221NZP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1355015:LK06 RS22330
gene id: 1355015:LK06_RS22330
uniprot id: A0A221P2L2
names: Similarity
messages: Belongs to the Fur family.

1355015:LK06 RS07470
gene id: 1355015:LK06_RS07470
uniprot id: A0A221NX12
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

1355015:LK06 RS08845
gene id: 1355015:LK06_RS08845
uniprot id: A0A221NWD4
names: Similarity
messages: Belongs to the CdaR family.

1355015:LK06 RS05015
gene id: 1355015:LK06_RS05015
uniprot id: A0A221NUP5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1355015:LK06 RS13050
gene id: 1355015:LK06_RS13050
uniprot id: A0A221NZP3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

1355015:LK06 RS03915
gene id: 1355015:LK06_RS03915
uniprot id: A0A221NUI2
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS21965
gene id: 1355015:LK06_RS21965
uniprot id: A0A221P2I0
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1355015:LK06 RS13330
gene id: 1355015:LK06_RS13330
uniprot id: A0A221NYD6
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1355015:LK06 RS25005
gene id: 1355015:LK06_RS25005
uniprot id: A0A221P4C2
names: Similarity
messages: Belongs to the Dps family.

1355015:LK06 RS03895
gene id: 1355015:LK06_RS03895
uniprot id: A0A221NU03
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS01480
gene id: 1355015:LK06_RS01480
uniprot id: A0A221NT04
names: Similarity
messages: Belongs to the thioredoxin family.

1355015:LK06 RS12465
gene id: 1355015:LK06_RS12465
uniprot id: A0A221NY06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1355015:LK06 RS26245
gene id: 1355015:LK06_RS26245
uniprot id: A0A221P4I3
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1355015:LK06 RS23245
gene id: 1355015:LK06_RS23245
uniprot id: A0A221P8U0
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1355015:LK06 RS24675
gene id: 1355015:LK06_RS24675
uniprot id: A0A221P413
names: Similarity
messages: Belongs to the CdaR family.

1355015:LK06 RS26565
gene id: 1355015:LK06_RS26565
uniprot id: A0A221P5U5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1355015:LK06 RS06170
gene id: 1355015:LK06_RS06170
uniprot id: A0A221NV96
names: Similarity
messages: Belongs to the asp23 family.

1355015:LK06 RS10795
gene id: 1355015:LK06_RS10795
uniprot id: A0A221NXB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1355015:LK06 RS20415
gene id: 1355015:LK06_RS20415
uniprot id: A0A221P1L9
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1355015:LK06 RS11170
gene id: 1355015:LK06_RS11170
uniprot id: A0A221NXH4
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS14375
gene id: 1355015:LK06_RS14375
uniprot id: A0A221NZ60
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1355015:LK06 RS03055
gene id: 1355015:LK06_RS03055
uniprot id: A0A221NTU8
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1355015:LK06 RS00180
gene id: 1355015:LK06_RS00180
uniprot id: A0A221NSD2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1355015:LK06 RS07750
gene id: 1355015:LK06_RS07750
uniprot id: A0A221NX65
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1355015:LK06 RS10815
gene id: 1355015:LK06_RS10815
uniprot id: A0A221NXI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1355015:LK06 RS01470
gene id: 1355015:LK06_RS01470
uniprot id: A0A221NT00
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1355015:LK06 RS25765
gene id: 1355015:LK06_RS25765
uniprot id: A0A221P5F7
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1355015:LK06 RS24505
gene id: 1355015:LK06_RS24505
uniprot id: A0A221P3X7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS11425
gene id: 1355015:LK06_RS11425
uniprot id: A0A221NXH6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS11250
gene id: 1355015:LK06_RS11250
uniprot id: A0A221NXZ4
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1355015:LK06 RS08470
gene id: 1355015:LK06_RS08470
uniprot id: A0A221NWS4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1355015:LK06 RS32130
gene id: 1355015:LK06_RS32130
uniprot id: A0A221P771
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS20360
gene id: 1355015:LK06_RS20360
uniprot id: A0A221P1K8
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1355015:LK06 RS31285
gene id: 1355015:LK06_RS31285
uniprot id: A0A221P718
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1355015:LK06 RS31255
gene id: 1355015:LK06_RS31255
uniprot id: A0A221P6T6
names: Similarity
messages: Belongs to the peptidase A31 family.

1355015:LK06 RS24130
gene id: 1355015:LK06_RS24130
uniprot id: A0A221P3E2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

1355015:LK06 RS11685
gene id: 1355015:LK06_RS11685
uniprot id: A0A221P842
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1355015:LK06 RS13945
gene id: 1355015:LK06_RS13945
uniprot id: A0A221NZ97
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS28220
gene id: 1355015:LK06_RS28220
uniprot id: A0A221P911
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1355015:LK06 RS11125
gene id: 1355015:LK06_RS11125
uniprot id: A0A221NYU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1355015:LK06 RS20915
gene id: 1355015:LK06_RS20915
uniprot id: A0A221P1W0
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS04045
gene id: 1355015:LK06_RS04045
uniprot id: A0A221NU84
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1355015:LK06 RS24430
gene id: 1355015:LK06_RS24430
uniprot id: A0A221P3J1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1355015:LK06 RS00265
gene id: 1355015:LK06_RS00265
uniprot id: A0A221NSK7
names: Similarity
messages: Belongs to the universal stress protein A family.

1355015:LK06 RS06615
gene id: 1355015:LK06_RS06615
uniprot id: A0A221NVJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1355015:LK06 RS18115
gene id: 1355015:LK06_RS18115
uniprot id: A0A221P0P5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1355015:LK06 RS22370
gene id: 1355015:LK06_RS22370
uniprot id: A0A221P359
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1355015:LK06 RS27640
gene id: 1355015:LK06_RS27640
uniprot id: A0A221P524
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1355015:LK06 RS11850
gene id: 1355015:LK06_RS11850
uniprot id: A0A221NXT2
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS07800
gene id: 1355015:LK06_RS07800
uniprot id: A0A221NVU9
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1355015:LK06 RS23835
gene id: 1355015:LK06_RS23835
uniprot id: A0A221P3R4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1355015:LK06 RS05595
gene id: 1355015:LK06_RS05595
uniprot id: A0A221NV33
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS12480
gene id: 1355015:LK06_RS12480
uniprot id: A0A221NZG0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1355015:LK06 RS07170
gene id: 1355015:LK06_RS07170
uniprot id: A0A221NVS6
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1355015:LK06 RS08620
gene id: 1355015:LK06_RS08620
uniprot id: A0A221NXN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1355015:LK06 RS31615
gene id: 1355015:LK06_RS31615
uniprot id: A0A221P786
names: Similarity
messages: Belongs to the FGGY kinase family.

1355015:LK06 RS21485
gene id: 1355015:LK06_RS21485
uniprot id: A0A221P281
names: Similarity
messages: Belongs to the FBPase class 2 family.

1355015:LK06 RS27185
gene id: 1355015:LK06_RS27185
uniprot id: A0A221P513
names: Similarity
messages: In the C-terminal section; belongs to the anthranilate synthase component I family.

1355015:LK06 RS10950
gene id: 1355015:LK06_RS10950
uniprot id: A0A221P839
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1355015:LK06 RS25185
gene id: 1355015:LK06_RS25185
uniprot id: A0A221P8Q5
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

1355015:LK06 RS05590
gene id: 1355015:LK06_RS05590
uniprot id: A0A221NUW2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1355015:LK06 RS02065
gene id: 1355015:LK06_RS02065
uniprot id: A0A221NTD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1355015:LK06 RS14485
gene id: 1355015:LK06_RS14485
uniprot id: A0A221NZ20
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS12940
gene id: 1355015:LK06_RS12940
uniprot id: A0A221NYC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1355015:LK06 RS02140
gene id: 1355015:LK06_RS02140
uniprot id: A0A221NTA6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS04015
gene id: 1355015:LK06_RS04015
uniprot id: A0A221NU89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1355015:LK06 RS26875
gene id: 1355015:LK06_RS26875
uniprot id: A0A221P4P6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1355015:LK06 RS06635
gene id: 1355015:LK06_RS06635
uniprot id: A0A221NVT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1355015:LK06 RS27970
gene id: 1355015:LK06_RS27970
uniprot id: A0A221P6K0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1355015:LK06 RS10615
gene id: 1355015:LK06_RS10615
uniprot id: A0A221NX52
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1355015:LK06 RS09295
gene id: 1355015:LK06_RS09295
uniprot id: A0A221NXZ9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1355015:LK06 RS29280
gene id: 1355015:LK06_RS29280
uniprot id: A0A221P5T5
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1355015:LK06 RS06070
gene id: 1355015:LK06_RS06070
uniprot id: A0A221NV45
names: Similarity
messages: Belongs to the peptidase S8 family.

1355015:LK06 RS28085
gene id: 1355015:LK06_RS28085
uniprot id: A0A221P5N2
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

1355015:LK06 RS17025
gene id: 1355015:LK06_RS17025
uniprot id: A0A221P0Q5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1355015:LK06 RS11640
gene id: 1355015:LK06_RS11640
uniprot id: A0A221NXQ4
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1355015:LK06 RS11990
gene id: 1355015:LK06_RS11990
uniprot id: A0A221NZ81
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1355015:LK06 RS09915
gene id: 1355015:LK06_RS09915
uniprot id: A0A221P7X2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1355015:LK06 RS04055
gene id: 1355015:LK06_RS04055
uniprot id: A0A221NUC3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1355015:LK06 RS22205
gene id: 1355015:LK06_RS22205
uniprot id: A0A221P8V7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1355015:LK06 RS24455
gene id: 1355015:LK06_RS24455
uniprot id: A0A221P3W4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1355015:LK06 RS16215
gene id: 1355015:LK06_RS16215
uniprot id: A0A221P031
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS09430
gene id: 1355015:LK06_RS09430
uniprot id: A0A221NWR6
names: Similarity
messages: Belongs to the peptidase S66 family.

1355015:LK06 RS04090
gene id: 1355015:LK06_RS04090
uniprot id: A0A221NUP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1355015:LK06 RS28830
gene id: 1355015:LK06_RS28830
uniprot id: A0A221P5H3
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1355015:LK06 RS24525
gene id: 1355015:LK06_RS24525
uniprot id: A0A221P464
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1355015:LK06 RS19275
gene id: 1355015:LK06_RS19275
uniprot id: A0A221P1E2
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1355015:LK06 RS22490
gene id: 1355015:LK06_RS22490
uniprot id: A0A221P377
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1355015:LK06 RS16290
gene id: 1355015:LK06_RS16290
uniprot id: A0A221P0B9
names: Similarity
messages: Belongs to the peptidase M24B family.

1355015:LK06 RS03965
gene id: 1355015:LK06_RS03965
uniprot id: A0A221NVC7
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS16010
gene id: 1355015:LK06_RS16010
uniprot id: A0A221NZM6
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS06560
gene id: 1355015:LK06_RS06560
uniprot id: A0A221NVI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1355015:LK06 RS24580
gene id: 1355015:LK06_RS24580
uniprot id: A0A221P3L6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1355015:LK06 RS18880
gene id: 1355015:LK06_RS18880
uniprot id: A0A221P120
names: Cofactor
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.

1355015:LK06 RS28765
gene id: 1355015:LK06_RS28765
uniprot id: A0A221P5K1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1355015:LK06 RS12255
gene id: 1355015:LK06_RS12255
uniprot id: A0A221NZC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1355015:LK06 RS31145
gene id: 1355015:LK06_RS31145
uniprot id: A0A221P6R4
names: Subcellular Location Annotation
messages: Secreted

1355015:LK06 RS12615
gene id: 1355015:LK06_RS12615
uniprot id: A0A221P9F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1355015:LK06 RS12025
gene id: 1355015:LK06_RS12025
uniprot id: A0A221NY49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1355015:LK06 RS23280
gene id: 1355015:LK06_RS23280
uniprot id: A0A221P307
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1355015:LK06 RS06265
gene id: 1355015:LK06_RS06265
uniprot id: A0A221NV34
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS13705
gene id: 1355015:LK06_RS13705
uniprot id: A0A221NYP9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1355015:LK06 RS27465
gene id: 1355015:LK06_RS27465
uniprot id: A0A221P5A1
names: Similarity
messages: Belongs to the IucA/IucC family.

1355015:LK06 RS06705
gene id: 1355015:LK06_RS06705
uniprot id: A0A221NVF4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1355015:LK06 RS14115
gene id: 1355015:LK06_RS14115
uniprot id: A0A221P8K5
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS27225
gene id: 1355015:LK06_RS27225
uniprot id: A0A221P4Z0
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS15300
gene id: 1355015:LK06_RS15300
uniprot id: A0A221P0Q7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1355015:LK06 RS31785
gene id: 1355015:LK06_RS31785
uniprot id: A0A221P6W4
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1355015:LK06 RS07230
gene id: 1355015:LK06_RS07230
uniprot id: A0A221NVK4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1355015:LK06 RS12730
gene id: 1355015:LK06_RS12730
uniprot id: A0A221NYG4
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS16625
gene id: 1355015:LK06_RS16625
uniprot id: A0A221NZZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Belongs to the glycosyltransferase 2 family.
messages: Membrane

1355015:LK06 RS09370
gene id: 1355015:LK06_RS09370
uniprot id: A0A221NX75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1355015:LK06 RS30650
gene id: 1355015:LK06_RS30650
uniprot id: A0A221P6D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1355015:LK06 RS25650
gene id: 1355015:LK06_RS25650
uniprot id: A0A221P481
names: Similarity
messages: Belongs to the thioesterase family.

1355015:LK06 RS28180
gene id: 1355015:LK06_RS28180
uniprot id: A0A221P5B1
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1355015:LK06 RS13830
gene id: 1355015:LK06_RS13830
uniprot id: A0A221NYQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1355015:LK06 RS10310
gene id: 1355015:LK06_RS10310
uniprot id: A0A221NYG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

1355015:LK06 RS04265
gene id: 1355015:LK06_RS04265
uniprot id: A0A221NUA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1355015:LK06 RS14500
gene id: 1355015:LK06_RS14500
uniprot id: A0A221NYW2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1355015:LK06 RS09315
gene id: 1355015:LK06_RS09315
uniprot id: A0A221NX66
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1355015:LK06 RS00520
gene id: 1355015:LK06_RS00520
uniprot id: A0A221NSL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1355015:LK06 RS28715
gene id: 1355015:LK06_RS28715
uniprot id: A0A221P5J2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1355015:LK06 RS11285
gene id: 1355015:LK06_RS11285
uniprot id: A0A221NXF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1355015:LK06 RS21470
gene id: 1355015:LK06_RS21470
uniprot id: A0A221P2R1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1355015:LK06 RS04175
gene id: 1355015:LK06_RS04175
uniprot id: A0A221NU48
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1355015:LK06 RS25995
gene id: 1355015:LK06_RS25995
uniprot id: A0A221P4E4
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1355015:LK06 RS18825
gene id: 1355015:LK06_RS18825
uniprot id: A0A221P101
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1355015:LK06 RS27315
gene id: 1355015:LK06_RS27315
uniprot id: A0A221P4Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1355015:LK06 RS07930
gene id: 1355015:LK06_RS07930
uniprot id: A0A221NXA2
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS30190
gene id: 1355015:LK06_RS30190
uniprot id: A0A221P6L4
names: Similarity
messages: Belongs to the universal stress protein A family.

1355015:LK06 RS08995
gene id: 1355015:LK06_RS08995
uniprot id: A0A221P8K9
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS20505
gene id: 1355015:LK06_RS20505
uniprot id: A0A221P1R5
names: Subcellular Location Annotation
messages: Membrane

1355015:LK06 RS19715
gene id: 1355015:LK06_RS19715
uniprot id: A0A221P1L2
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1355015:LK06 RS03130
gene id: 1355015:LK06_RS03130
uniprot id: A0A221NU62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1355015:LK06 RS04050
gene id: 1355015:LK06_RS04050
uniprot id: A0A221NU73
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1355015:LK06 RS16000
gene id: 1355015:LK06_RS16000
uniprot id: A0A221NZP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.