1347342:BN863 RS17335
gene id: 1347342:BN863_RS17335
uniprot id: T2KRN4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1347342:BN863 RS16840
gene id: 1347342:BN863_RS16840
uniprot id: T2KRI7
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1347342:BN863 RS13760
gene id: 1347342:BN863_RS13760
uniprot id: T2KNK4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1347342:BN863 RS12360
gene id: 1347342:BN863_RS12360
uniprot id: T2KP06
names: Similarity
messages: Belongs to the nitroreductase family.

1347342:BN863 RS00990
gene id: 1347342:BN863_RS00990
uniprot id: T2KGL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1347342:BN863 RS01930
gene id: 1347342:BN863_RS01930
uniprot id: T2KI41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1347342:BN863 RS12460
gene id: 1347342:BN863_RS12460
uniprot id: T2KP13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1347342:BN863 RS01510
gene id: 1347342:BN863_RS01510
uniprot id: T2KGU6
names: Similarity
messages: Belongs to the fabD family.

1347342:BN863 RS13540
gene id: 1347342:BN863_RS13540
uniprot id: T2KPJ8
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1347342:BN863 RS02880
gene id: 1347342:BN863_RS02880
uniprot id: T2KHI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1347342:BN863 RS17660
gene id: 1347342:BN863_RS17660
uniprot id: T2KRV0
names: Similarity
messages: Belongs to the Skp family.

1347342:BN863 RS00215
gene id: 1347342:BN863_RS00215
uniprot id: T2KH77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1347342:BN863 RS07855
gene id: 1347342:BN863_RS07855
uniprot id: T2KMS5
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

1347342:BN863 RS02845
gene id: 1347342:BN863_RS02845
uniprot id: T2KIL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1347342:BN863 RS14780
gene id: 1347342:BN863_RS14780
uniprot id: T2KQC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1347342:BN863 RS13015
gene id: 1347342:BN863_RS13015
uniprot id: T2KQR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1347342:BN863 RS10885
gene id: 1347342:BN863_RS10885
uniprot id: T2KN88
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1347342:BN863 RS04130
gene id: 1347342:BN863_RS04130
uniprot id: T2KJC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1347342:BN863 RS04145
gene id: 1347342:BN863_RS04145
uniprot id: T2KKI6
names: Similarity
messages: Belongs to the group II decarboxylase family.

1347342:BN863 RS17380
gene id: 1347342:BN863_RS17380
uniprot id: T2KQR2
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1347342:BN863 RS13460
gene id: 1347342:BN863_RS13460
uniprot id: T2KPM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1347342:BN863 RS03970
gene id: 1347342:BN863_RS03970
uniprot id: T2KI09
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS03135
gene id: 1347342:BN863_RS03135
uniprot id: T2KHR2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1347342:BN863 RS03765
gene id: 1347342:BN863_RS03765
uniprot id: T2KHX0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1347342:BN863 RS07485
gene id: 1347342:BN863_RS07485
uniprot id: T2KJY3
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1347342:BN863 RS15425
gene id: 1347342:BN863_RS15425
uniprot id: T2KQR4
names: Similarity
messages: Belongs to the SusD family.

1347342:BN863 RS02170
gene id: 1347342:BN863_RS02170
uniprot id: T2KH21
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1347342:BN863 RS13120
gene id: 1347342:BN863_RS13120
uniprot id: T2KNN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

1347342:BN863 RS09210
gene id: 1347342:BN863_RS09210
uniprot id: T2KNI5
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

1347342:BN863 RS12015
gene id: 1347342:BN863_RS12015
uniprot id: T2KQ48
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1347342:BN863 RS17215
gene id: 1347342:BN863_RS17215
uniprot id: T2KRK8
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1347342:BN863 RS07080
gene id: 1347342:BN863_RS07080
uniprot id: T2KKZ9
names: Similarity
messages: Belongs to the porin LamB (TC 1.B.3) family.

1347342:BN863 RS07260
gene id: 1347342:BN863_RS07260
uniprot id: T2KL41
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS17100
gene id: 1347342:BN863_RS17100
uniprot id: T2KRH6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1347342:BN863 RS03375
gene id: 1347342:BN863_RS03375
uniprot id: T2KHV7
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

1347342:BN863 RS17110
gene id: 1347342:BN863_RS17110
uniprot id: T2KQW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1347342:BN863 RS01935
gene id: 1347342:BN863_RS01935
uniprot id: T2KJC5
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1347342:BN863 RS06360
gene id: 1347342:BN863_RS06360
uniprot id: T2KKJ9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1347342:BN863 RS09730
gene id: 1347342:BN863_RS09730
uniprot id: T2KMH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1347342:BN863 RS02710
gene id: 1347342:BN863_RS02710
uniprot id: T2KIJ7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1347342:BN863 RS11880
gene id: 1347342:BN863_RS11880
uniprot id: T2KMH3
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1347342:BN863 RS05330
gene id: 1347342:BN863_RS05330
uniprot id: T2KIY5
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1347342:BN863 RS06065
gene id: 1347342:BN863_RS06065
uniprot id: T2KLN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1347342:BN863 RS01395
gene id: 1347342:BN863_RS01395
uniprot id: T2KHT2
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1347342:BN863 RS05660
gene id: 1347342:BN863_RS05660
uniprot id: T2KK95
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1347342:BN863 RS16235
gene id: 1347342:BN863_RS16235
uniprot id: T2KR13
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1347342:BN863 RS14060
gene id: 1347342:BN863_RS14060
uniprot id: T2KPT9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1347342:BN863 RS00455
gene id: 1347342:BN863_RS00455
uniprot id: T2KGD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1347342:BN863 RS05625
gene id: 1347342:BN863_RS05625
uniprot id: T2KLG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1347342:BN863 RS16765
gene id: 1347342:BN863_RS16765
uniprot id: T2KRH1
names: Similarity
messages: Belongs to the ArsC family.

1347342:BN863 RS16900
gene id: 1347342:BN863_RS16900
uniprot id: T2KRE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1347342:BN863 RS07425
gene id: 1347342:BN863_RS07425
uniprot id: T2KK92
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1347342:BN863 RS01305
gene id: 1347342:BN863_RS01305
uniprot id: T2KHS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1347342:BN863 RS00610
gene id: 1347342:BN863_RS00610
uniprot id: T2KGD3
names: Similarity
messages: Belongs to the peptidase S9C family.

1347342:BN863 RS05020
gene id: 1347342:BN863_RS05020
uniprot id: T2KJU0
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS10375
gene id: 1347342:BN863_RS10375
uniprot id: T2KLK9
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1347342:BN863 RS11055
gene id: 1347342:BN863_RS11055
uniprot id: T2KMH5
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 37 family.
messages: Broad-specificity lyase involved in ulvan degradation (PubMed:30279430). Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall. It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (PubMed:30279430) (Probable). Ulvan lyase catalyzes the endolytic cleavage of the glycosidic bond between Rha3S and the uronic acids GlcA or IduA, producing oligosaccharides that have unsaturated 4-deoxy-L-threo-hex-4-enopyranosiduronic acid (deltaUA) at the non-reducing end. This results eventually in the degradation of the ulvan polysaccharide into deltaUA-Rha3S disaccharides and deltaUA-Rha3S-Xyl-Rha3S tetrasaccharides. It is also able to degrade the glycosaminoglycans heparan sulfate and chondroitin sulfate. Not active against pectin, xanthan or alginate (PubMed:30279430).
messages: By ulvan and rhamnose.
messages: Periplasm

1347342:BN863 RS10790
gene id: 1347342:BN863_RS10790
uniprot id: T2KPG4
names: Similarity
messages: Belongs to the aldose epimerase family.

1347342:BN863 RS16655
gene id: 1347342:BN863_RS16655
uniprot id: T2KS94
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

1347342:BN863 RS04115
gene id: 1347342:BN863_RS04115
uniprot id: T2KI36
names: Similarity
messages: Belongs to the CinA family.

1347342:BN863 RS15920
gene id: 1347342:BN863_RS15920
uniprot id: T2KQV3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1347342:BN863 RS01615
gene id: 1347342:BN863_RS01615
uniprot id: T2KHX3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1347342:BN863 RS10460
gene id: 1347342:BN863_RS10460
uniprot id: T2KM76
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1347342:BN863 RS02840
gene id: 1347342:BN863_RS02840
uniprot id: T2KHE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1347342:BN863 RS02475
gene id: 1347342:BN863_RS02475
uniprot id: T2KJN1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1347342:BN863 RS02950
gene id: 1347342:BN863_RS02950
uniprot id: T2KJX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1347342:BN863 RS00005
gene id: 1347342:BN863_RS00005
uniprot id: T2KH40
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS10250
gene id: 1347342:BN863_RS10250
uniprot id: T2KLI1
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1347342:BN863 RS14905
gene id: 1347342:BN863_RS14905
uniprot id: T2KPA5
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS13880
gene id: 1347342:BN863_RS13880
uniprot id: T2KNN5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1347342:BN863 RS00400
gene id: 1347342:BN863_RS00400
uniprot id: T2KGB6
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

1347342:BN863 RS08530
gene id: 1347342:BN863_RS08530
uniprot id: T2KN52
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS11790
gene id: 1347342:BN863_RS11790
uniprot id: T2KMV1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS02620
gene id: 1347342:BN863_RS02620
uniprot id: T2KIG6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1347342:BN863 RS12290
gene id: 1347342:BN863_RS12290
uniprot id: T2KNY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1347342:BN863 RS09745
gene id: 1347342:BN863_RS09745
uniprot id: T2KMK2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1347342:BN863 RS10935
gene id: 1347342:BN863_RS10935
uniprot id: T2KN98
names: Cofactor
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: By ulvan and rhamnose.
messages: Cytoplasm
messages: Isomerase involved in ulvan degradation (Probable). Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall. It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (Probable). Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity).

1347342:BN863 RS04690
gene id: 1347342:BN863_RS04690
uniprot id: T2KJM8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1347342:BN863 RS00690
gene id: 1347342:BN863_RS00690
uniprot id: T2KHH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1347342:BN863 RS16865
gene id: 1347342:BN863_RS16865
uniprot id: T2KRJ3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1347342:BN863 RS05855
gene id: 1347342:BN863_RS05855
uniprot id: T2KJ13
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

1347342:BN863 RS11060
gene id: 1347342:BN863_RS11060
uniprot id: T2KNC2
names: Domain
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 28 family.
messages: By ulvan and rhamnose.
messages: Secreted
messages: The ulvan-binding domain binds strongly to ulvan, it does not bind other polymers like alginate, heparin, dextran sulfate or iota carrageenan. Presumably it serves to anchor the enzyme at the substrate, thus improving catalysis. Notably, the catalytic domain alone is more active than the full-length enzyme with the binding domain attached. Possibly, the ulvan-binding domain helps the enzyme to act on ulvan in its insoluble form embedded in the algal cell wall.
messages: Ulvan lyase involved in ulvan degradation (Ref.2). Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall. It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (Probable). Ulvan lyase catalyzes the endolytic cleavage of the glycosidic bond between Rha3S and the uronic acids GlcA or IduA, producing oligosaccharides that have unsaturated 4-deoxy-L-threo-hex-4-enopyranosiduronic acid (deltaUA) at the non-reducing end. This results eventually in the degradation of the ulvan polysaccharide into deltaUA-Rha3S disaccharides and deltaUA-Rha3S-Xyl-Rha3S tetrasaccharides (PubMed:29948117, PubMed:31285597).

1347342:BN863 RS00290
gene id: 1347342:BN863_RS00290
uniprot id: T2KH93
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1347342:BN863 RS13545
gene id: 1347342:BN863_RS13545
uniprot id: T2KR01
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS01390
gene id: 1347342:BN863_RS01390
uniprot id: T2KGS9
names: Similarity
messages: Belongs to the Skp family.

1347342:BN863 RS01330
gene id: 1347342:BN863_RS01330
uniprot id: T2KHT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1347342:BN863 RS00650
gene id: 1347342:BN863_RS00650
uniprot id: T2KGG2
names: Similarity
messages: Belongs to the aspartokinase family.

1347342:BN863 RS04795
gene id: 1347342:BN863_RS04795
uniprot id: T2KKX6
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1347342:BN863 RS15485
gene id: 1347342:BN863_RS15485
uniprot id: T2KQP0
names: Function
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.
messages: Belongs to the cellobiose 2-epimerase family.
messages: Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man).

1347342:BN863 RS06660
gene id: 1347342:BN863_RS06660
uniprot id: T2KJG4
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1347342:BN863 RS16835
gene id: 1347342:BN863_RS16835
uniprot id: T2KQQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1347342:BN863 RS16125
gene id: 1347342:BN863_RS16125
uniprot id: T2KQC6
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1347342:BN863 RS06635
gene id: 1347342:BN863_RS06635
uniprot id: T2KKS1
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1347342:BN863 RS10570
gene id: 1347342:BN863_RS10570
uniprot id: T2KPC4
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1347342:BN863 RS03715
gene id: 1347342:BN863_RS03715
uniprot id: T2KHW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1347342:BN863 RS17655
gene id: 1347342:BN863_RS17655
uniprot id: T2KQX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1347342:BN863 RS00835
gene id: 1347342:BN863_RS00835
uniprot id: T2KGI9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS05725
gene id: 1347342:BN863_RS05725
uniprot id: T2KKA6
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1347342:BN863 RS03495
gene id: 1347342:BN863_RS03495
uniprot id: T2KHY1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1347342:BN863 RS03065
gene id: 1347342:BN863_RS03065
uniprot id: T2KIT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1347342:BN863 RS04835
gene id: 1347342:BN863_RS04835
uniprot id: T2KIG1
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

1347342:BN863 RS04135
gene id: 1347342:BN863_RS04135
uniprot id: T2KI39
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1347342:BN863 RS01335
gene id: 1347342:BN863_RS01335
uniprot id: T2KJ09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Cytoplasm

1347342:BN863 RS02450
gene id: 1347342:BN863_RS02450
uniprot id: T2KJM5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1347342:BN863 RS07120
gene id: 1347342:BN863_RS07120
uniprot id: T2KJQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1347342:BN863 RS08620
gene id: 1347342:BN863_RS08620
uniprot id: T2KKM6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1347342:BN863 RS04255
gene id: 1347342:BN863_RS04255
uniprot id: T2KJF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1347342:BN863 RS10805
gene id: 1347342:BN863_RS10805
uniprot id: T2KLX1
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1347342:BN863 RS11595
gene id: 1347342:BN863_RS11595
uniprot id: T2KMB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1347342:BN863 RS15190
gene id: 1347342:BN863_RS15190
uniprot id: T2KRT1
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1347342:BN863 RS01970
gene id: 1347342:BN863_RS01970
uniprot id: T2KI42
names: Similarity
messages: Belongs to the peptidase S15 family.

1347342:BN863 RS16795
gene id: 1347342:BN863_RS16795
uniprot id: T2KQF6
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1347342:BN863 RS05835
gene id: 1347342:BN863_RS05835
uniprot id: T2KLJ9
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1347342:BN863 RS03475
gene id: 1347342:BN863_RS03475
uniprot id: T2KHX7
names: Similarity
messages: Belongs to the glutamine synthetase family.

1347342:BN863 RS04915
gene id: 1347342:BN863_RS04915
uniprot id: T2KJS2
names: Similarity
messages: Belongs to the group II decarboxylase family.

1347342:BN863 RS00510
gene id: 1347342:BN863_RS00510
uniprot id: T2KHD7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1347342:BN863 RS12150
gene id: 1347342:BN863_RS12150
uniprot id: T2KN10
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1347342:BN863 RS02575
gene id: 1347342:BN863_RS02575
uniprot id: T2KJQ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1347342:BN863 RS11820
gene id: 1347342:BN863_RS11820
uniprot id: T2KNQ7
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1347342:BN863 RS01985
gene id: 1347342:BN863_RS01985
uniprot id: T2KJD3
names: Similarity
messages: Belongs to the NAD synthetase family.

1347342:BN863 RS12285
gene id: 1347342:BN863_RS12285
uniprot id: T2KMP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1347342:BN863 RS10190
gene id: 1347342:BN863_RS10190
uniprot id: T2KLZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

1347342:BN863 RS04975
gene id: 1347342:BN863_RS04975
uniprot id: T2KIQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1347342:BN863 RS00720
gene id: 1347342:BN863_RS00720
uniprot id: T2KIQ5
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS02370
gene id: 1347342:BN863_RS02370
uniprot id: T2KIB9
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS11090
gene id: 1347342:BN863_RS11090
uniprot id: T2KM26
names: Cofactor
names: Function
names: Induction
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Bifunctional enzyme containing sulfatase and alpha-L-rhamnosidase activities involved in ulvan degradation (PubMed:31285597). Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall. It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (Probable). The sulfatase specifically desulfates L-rhamnose at the 3-position and can act on the motif Rha3S-Xyl-Rha3S in an exolytic mode of action, producing Rha-Xyl-Rha3S. Also desulfates Rha3S monosaccharides, which are produced by the action of unsaturated glucuronyl hydrolases acting on ulvan oligomers (PubMed:31285597).
messages: Binds 1 Ca(2+) ion per subunit.
messages: By ulvan and rhamnose.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 78 family.
messages: In the N-terminal section; belongs to the sulfatase family.
messages: Periplasm
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. This post-translational modification is severely defective in multiple sulfatase deficiency (MSD).

1347342:BN863 RS15030
gene id: 1347342:BN863_RS15030
uniprot id: T2KPD1
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1347342:BN863 RS15935
gene id: 1347342:BN863_RS15935
uniprot id: T2KR26
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS10625
gene id: 1347342:BN863_RS10625
uniprot id: T2KLT5
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

1347342:BN863 RS00930
gene id: 1347342:BN863_RS00930
uniprot id: T2KIT6
names: Similarity
messages: Belongs to the asparaginase 1 family.

1347342:BN863 RS13905
gene id: 1347342:BN863_RS13905
uniprot id: T2KNP1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1347342:BN863 RS01005
gene id: 1347342:BN863_RS01005
uniprot id: T2KHM6
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1347342:BN863 RS04675
gene id: 1347342:BN863_RS04675
uniprot id: T2KIJ9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1347342:BN863 RS09010
gene id: 1347342:BN863_RS09010
uniprot id: T2KK41
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1347342:BN863 RS11715
gene id: 1347342:BN863_RS11715
uniprot id: T2KMU0
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1347342:BN863 RS09645
gene id: 1347342:BN863_RS09645
uniprot id: T2KMI4
names: Similarity
messages: Belongs to the SusD family.

1347342:BN863 RS13200
gene id: 1347342:BN863_RS13200
uniprot id: T2KNA5
names: Similarity
messages: Belongs to the SusD family.

1347342:BN863 RS11665
gene id: 1347342:BN863_RS11665
uniprot id: T2KMT2
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1347342:BN863 RS04765
gene id: 1347342:BN863_RS04765
uniprot id: T2KIE7
names: Similarity
messages: Belongs to the SusD family.

1347342:BN863 RS03060
gene id: 1347342:BN863_RS03060
uniprot id: T2KHP6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1347342:BN863 RS11915
gene id: 1347342:BN863_RS11915
uniprot id: T2KQ31
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1347342:BN863 RS16910
gene id: 1347342:BN863_RS16910
uniprot id: T2KQS0
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1347342:BN863 RS14975
gene id: 1347342:BN863_RS14975
uniprot id: T2KPM7
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1347342:BN863 RS07395
gene id: 1347342:BN863_RS07395
uniprot id: T2KMG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1347342:BN863 RS06405
gene id: 1347342:BN863_RS06405
uniprot id: T2KKK9
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1347342:BN863 RS00855
gene id: 1347342:BN863_RS00855
uniprot id: T2KIS6
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS16650
gene id: 1347342:BN863_RS16650
uniprot id: T2KR91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1347342:BN863 RS01535
gene id: 1347342:BN863_RS01535
uniprot id: T2KGV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1347342:BN863 RS17825
gene id: 1347342:BN863_RS17825
uniprot id: T2KRC1
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1347342:BN863 RS02400
gene id: 1347342:BN863_RS02400
uniprot id: T2KJL7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1347342:BN863 RS01740
gene id: 1347342:BN863_RS01740
uniprot id: T2KGY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1347342:BN863 RS13525
gene id: 1347342:BN863_RS13525
uniprot id: T2KNV0
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1347342:BN863 RS16085
gene id: 1347342:BN863_RS16085
uniprot id: T2KQ14
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1347342:BN863 RS04995
gene id: 1347342:BN863_RS04995
uniprot id: T2KL18
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1347342:BN863 RS13960
gene id: 1347342:BN863_RS13960
uniprot id: T2KPW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1347342:BN863 RS11875
gene id: 1347342:BN863_RS11875
uniprot id: T2KNR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1347342:BN863 RS01160
gene id: 1347342:BN863_RS01160
uniprot id: T2KIX6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1347342:BN863 RS02920
gene id: 1347342:BN863_RS02920
uniprot id: T2KIM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1347342:BN863 RS04990
gene id: 1347342:BN863_RS04990
uniprot id: T2KJT6
names: Function
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.

1347342:BN863 RS15000
gene id: 1347342:BN863_RS15000
uniprot id: T2KPN3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1347342:BN863 RS07070
gene id: 1347342:BN863_RS07070
uniprot id: T2KL01
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1347342:BN863 RS02815
gene id: 1347342:BN863_RS02815
uniprot id: T2KHD6
names: Similarity
messages: Belongs to the SusD family.

1347342:BN863 RS10585
gene id: 1347342:BN863_RS10585
uniprot id: T2KN11
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1347342:BN863 RS10435
gene id: 1347342:BN863_RS10435
uniprot id: T2KPA6
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1347342:BN863 RS13980
gene id: 1347342:BN863_RS13980
uniprot id: T2KP26
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1347342:BN863 RS02595
gene id: 1347342:BN863_RS02595
uniprot id: T2KIG4
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1347342:BN863 RS07225
gene id: 1347342:BN863_RS07225
uniprot id: T2KMC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1347342:BN863 RS17575
gene id: 1347342:BN863_RS17575
uniprot id: T2KRV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1347342:BN863 RS00130
gene id: 1347342:BN863_RS00130
uniprot id: T2KH56
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1347342:BN863 RS11310
gene id: 1347342:BN863_RS11310
uniprot id: T2KNE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1347342:BN863 RS16985
gene id: 1347342:BN863_RS16985
uniprot id: T2KQT7
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

1347342:BN863 RS05560
gene id: 1347342:BN863_RS05560
uniprot id: T2KK77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1347342:BN863 RS06115
gene id: 1347342:BN863_RS06115
uniprot id: T2KLP7
names: Similarity
messages: Belongs to the peptidase C1 family.

1347342:BN863 RS07005
gene id: 1347342:BN863_RS07005
uniprot id: T2KKY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1347342:BN863 RS16080
gene id: 1347342:BN863_RS16080
uniprot id: T2KR48
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1347342:BN863 RS08655
gene id: 1347342:BN863_RS08655
uniprot id: T2KLV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1347342:BN863 RS03720
gene id: 1347342:BN863_RS03720
uniprot id: T2KJ28
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1347342:BN863 RS16010
gene id: 1347342:BN863_RS16010
uniprot id: T2KR37
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1347342:BN863 RS00375
gene id: 1347342:BN863_RS00375
uniprot id: T2KGB4
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1347342:BN863 RS02085
gene id: 1347342:BN863_RS02085
uniprot id: T2KH39
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS02995
gene id: 1347342:BN863_RS02995
uniprot id: T2KHI7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1347342:BN863 RS03885
gene id: 1347342:BN863_RS03885
uniprot id: T2KJ76
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1347342:BN863 RS02600
gene id: 1347342:BN863_RS02600
uniprot id: T2KJQ3
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1347342:BN863 RS03420
gene id: 1347342:BN863_RS03420
uniprot id: T2KK61
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1347342:BN863 RS16595
gene id: 1347342:BN863_RS16595
uniprot id: T2KQC0
names: Similarity
messages: Belongs to the peptidase M13 family.

1347342:BN863 RS06930
gene id: 1347342:BN863_RS06930
uniprot id: T2KKW9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1347342:BN863 RS09085
gene id: 1347342:BN863_RS09085
uniprot id: T2KKV9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1347342:BN863 RS03705
gene id: 1347342:BN863_RS03705
uniprot id: T2KI16
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1347342:BN863 RS15760
gene id: 1347342:BN863_RS15760
uniprot id: T2KQS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1347342:BN863 RS03230
gene id: 1347342:BN863_RS03230
uniprot id: T2KIW4
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1347342:BN863 RS06795
gene id: 1347342:BN863_RS06795
uniprot id: T2KK41
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1347342:BN863 RS07060
gene id: 1347342:BN863_RS07060
uniprot id: T2KM80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1347342:BN863 RS00135
gene id: 1347342:BN863_RS00135
uniprot id: T2KG81
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1347342:BN863 RS11835
gene id: 1347342:BN863_RS11835
uniprot id: T2KQ16
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1347342:BN863 RS13840
gene id: 1347342:BN863_RS13840
uniprot id: T2KPQ0
names: Similarity
messages: Belongs to the TrpC family.

1347342:BN863 RS03220
gene id: 1347342:BN863_RS03220
uniprot id: T2KK31
names: Similarity
messages: Belongs to the asparagine synthetase family.

1347342:BN863 RS04810
gene id: 1347342:BN863_RS04810
uniprot id: T2KIF7
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS00970
gene id: 1347342:BN863_RS00970
uniprot id: T2KHK2
names: Similarity
messages: Belongs to the sigma-54 factor family.

1347342:BN863 RS12100
gene id: 1347342:BN863_RS12100
uniprot id: T2KMZ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1347342:BN863 RS01035
gene id: 1347342:BN863_RS01035
uniprot id: T2KIV4
names: Similarity
messages: Belongs to the peptidase C56 family.

1347342:BN863 RS08455
gene id: 1347342:BN863_RS08455
uniprot id: T2KN39
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

1347342:BN863 RS03535
gene id: 1347342:BN863_RS03535
uniprot id: T2KIZ9
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1347342:BN863 RS16665
gene id: 1347342:BN863_RS16665
uniprot id: T2KRF6
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1347342:BN863 RS06110
gene id: 1347342:BN863_RS06110
uniprot id: T2KKE8
names: Similarity
messages: Belongs to the CvfB family.

1347342:BN863 RS14080
gene id: 1347342:BN863_RS14080
uniprot id: T2KK41
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1347342:BN863 RS02420
gene id: 1347342:BN863_RS02420
uniprot id: T2KIC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1347342:BN863 RS04820
gene id: 1347342:BN863_RS04820
uniprot id: T2KKY2
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1347342:BN863 RS17685
gene id: 1347342:BN863_RS17685
uniprot id: T2KRV5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1347342:BN863 RS10875
gene id: 1347342:BN863_RS10875
uniprot id: T2KN55
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS18690
gene id: 1347342:BN863_RS18690
uniprot id: T2KPB9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1347342:BN863 RS17275
gene id: 1347342:BN863_RS17275
uniprot id: T2KRR5
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1347342:BN863 RS02215
gene id: 1347342:BN863_RS02215
uniprot id: T2KI93
names: Similarity
messages: Belongs to the arginase family.

1347342:BN863 RS01240
gene id: 1347342:BN863_RS01240
uniprot id: T2KGQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Membrane

1347342:BN863 RS08615
gene id: 1347342:BN863_RS08615
uniprot id: T2KLY1
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1347342:BN863 RS16185
gene id: 1347342:BN863_RS16185
uniprot id: T2KR02
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1347342:BN863 RS02865
gene id: 1347342:BN863_RS02865
uniprot id: T2KHE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1347342:BN863 RS06410
gene id: 1347342:BN863_RS06410
uniprot id: T2KLV2
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.

1347342:BN863 RS10185
gene id: 1347342:BN863_RS10185
uniprot id: T2KP44
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1347342:BN863 RS01750
gene id: 1347342:BN863_RS01750
uniprot id: T2KGV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.
messages: Homotrimer.

1347342:BN863 RS04940
gene id: 1347342:BN863_RS04940
uniprot id: T2KJS7
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS01755
gene id: 1347342:BN863_RS01755
uniprot id: T2KI06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1347342:BN863 RS05670
gene id: 1347342:BN863_RS05670
uniprot id: T2KK72
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1347342:BN863 RS17005
gene id: 1347342:BN863_RS17005
uniprot id: T2KSB1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1347342:BN863 RS00140
gene id: 1347342:BN863_RS00140
uniprot id: T2KH64
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1347342:BN863 RS17845
gene id: 1347342:BN863_RS17845
uniprot id: T2KSE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1347342:BN863 RS06720
gene id: 1347342:BN863_RS06720
uniprot id: T2KJV4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS07720
gene id: 1347342:BN863_RS07720
uniprot id: T2KLD7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1347342:BN863 RS02965
gene id: 1347342:BN863_RS02965
uniprot id: T2KIQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1347342:BN863 RS03225
gene id: 1347342:BN863_RS03225
uniprot id: T2KHT1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1347342:BN863 RS17590
gene id: 1347342:BN863_RS17590
uniprot id: T2KSD5
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1347342:BN863 RS13430
gene id: 1347342:BN863_RS13430
uniprot id: T2KNT4
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS13780
gene id: 1347342:BN863_RS13780
uniprot id: T2KNZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1347342:BN863 RS03745
gene id: 1347342:BN863_RS03745
uniprot id: T2KJ33
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

1347342:BN863 RS17760
gene id: 1347342:BN863_RS17760
uniprot id: T2KR00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1347342:BN863 RS11455
gene id: 1347342:BN863_RS11455
uniprot id: T2KNH0
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1347342:BN863 RS03270
gene id: 1347342:BN863_RS03270
uniprot id: T2KK38
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS07050
gene id: 1347342:BN863_RS07050
uniprot id: T2KJP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1347342:BN863 RS07340
gene id: 1347342:BN863_RS07340
uniprot id: T2KL55
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1347342:BN863 RS12195
gene id: 1347342:BN863_RS12195
uniprot id: T2KQ88
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1347342:BN863 RS06925
gene id: 1347342:BN863_RS06925
uniprot id: T2KJL9
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1347342:BN863 RS07355
gene id: 1347342:BN863_RS07355
uniprot id: T2KL63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1347342:BN863 RS12665
gene id: 1347342:BN863_RS12665
uniprot id: T2KNB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1347342:BN863 RS09860
gene id: 1347342:BN863_RS09860
uniprot id: T2KNW9
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase 20 family.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the trehalose phosphatase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 20 family.

1347342:BN863 RS04890
gene id: 1347342:BN863_RS04890
uniprot id: T2KJR5
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1347342:BN863 RS11730
gene id: 1347342:BN863_RS11730
uniprot id: T2KNM3
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS07210
gene id: 1347342:BN863_RS07210
uniprot id: T2KL32
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1347342:BN863 RS04315
gene id: 1347342:BN863_RS04315
uniprot id: T2KJF4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1347342:BN863 RS02940
gene id: 1347342:BN863_RS02940
uniprot id: T2KHF7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1347342:BN863 RS17735
gene id: 1347342:BN863_RS17735
uniprot id: T2KRW1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1347342:BN863 RS15795
gene id: 1347342:BN863_RS15795
uniprot id: T2KQ68
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1347342:BN863 RS10720
gene id: 1347342:BN863_RS10720
uniprot id: T2KMC1
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1347342:BN863 RS17740
gene id: 1347342:BN863_RS17740
uniprot id: T2KSE1
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1347342:BN863 RS06740
gene id: 1347342:BN863_RS06740
uniprot id: T2KM22
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1347342:BN863 RS09775
gene id: 1347342:BN863_RS09775
uniprot id: T2KL93
names: Similarity
messages: Belongs to the LOG family.

1347342:BN863 RS08295
gene id: 1347342:BN863_RS08295
uniprot id: T2KLS1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1347342:BN863 RS07400
gene id: 1347342:BN863_RS07400
uniprot id: T2KK87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1347342:BN863 RS15900
gene id: 1347342:BN863_RS15900
uniprot id: T2KS11
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1347342:BN863 RS02415
gene id: 1347342:BN863_RS02415
uniprot id: T2KH65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1347342:BN863 RS17135
gene id: 1347342:BN863_RS17135
uniprot id: T2KQM3
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS17765
gene id: 1347342:BN863_RS17765
uniprot id: T2KRW4
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1347342:BN863 RS12065
gene id: 1347342:BN863_RS12065
uniprot id: T2KQ61
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1347342:BN863 RS12450
gene id: 1347342:BN863_RS12450
uniprot id: T2KMS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1347342:BN863 RS04265
gene id: 1347342:BN863_RS04265
uniprot id: T2KJE2
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1347342:BN863 RS07190
gene id: 1347342:BN863_RS07190
uniprot id: T2KL28
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1347342:BN863 RS04005
gene id: 1347342:BN863_RS04005
uniprot id: T2KI73
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS16435
gene id: 1347342:BN863_RS16435
uniprot id: T2KQI5
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1347342:BN863 RS04540
gene id: 1347342:BN863_RS04540
uniprot id: T2KIH5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS03395
gene id: 1347342:BN863_RS03395
uniprot id: T2KK55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1347342:BN863 RS01165
gene id: 1347342:BN863_RS01165
uniprot id: T2KGP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1347342:BN863 RS15465
gene id: 1347342:BN863_RS15465
uniprot id: T2KRX4
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer.
messages: Secreted

1347342:BN863 RS15500
gene id: 1347342:BN863_RS15500
uniprot id: T2KQV1
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

1347342:BN863 RS09410
gene id: 1347342:BN863_RS09410
uniprot id: T2KLG5
names: Similarity
messages: Belongs to the type IB topoisomerase family.

1347342:BN863 RS06315
gene id: 1347342:BN863_RS06315
uniprot id: T2KLT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1347342:BN863 RS17525
gene id: 1347342:BN863_RS17525
uniprot id: T2KRV1
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS00200
gene id: 1347342:BN863_RS00200
uniprot id: T2KGB1
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1347342:BN863 RS10090
gene id: 1347342:BN863_RS10090
uniprot id: T2KLW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1347342:BN863 RS06735
gene id: 1347342:BN863_RS06735
uniprot id: T2KKS9
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1347342:BN863 RS16310
gene id: 1347342:BN863_RS16310
uniprot id: T2KS61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1347342:BN863 RS14705
gene id: 1347342:BN863_RS14705
uniprot id: T2KP65
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS02985
gene id: 1347342:BN863_RS02985
uniprot id: T2KHL8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1347342:BN863 RS05385
gene id: 1347342:BN863_RS05385
uniprot id: T2KK25
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1347342:BN863 RS12420
gene id: 1347342:BN863_RS12420
uniprot id: T2KP14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1347342:BN863 RS02970
gene id: 1347342:BN863_RS02970
uniprot id: T2KHH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1347342:BN863 RS07195
gene id: 1347342:BN863_RS07195
uniprot id: T2KL26
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS16635
gene id: 1347342:BN863_RS16635
uniprot id: T2KQM2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1347342:BN863 RS10060
gene id: 1347342:BN863_RS10060
uniprot id: T2KP16
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1347342:BN863 RS09810
gene id: 1347342:BN863_RS09810
uniprot id: T2KNV5
names: Similarity
messages: Belongs to the DEAD box helicase family.

1347342:BN863 RS10710
gene id: 1347342:BN863_RS10710
uniprot id: T2KK41
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1347342:BN863 RS14245
gene id: 1347342:BN863_RS14245
uniprot id: T2KQ17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1347342:BN863 RS07115
gene id: 1347342:BN863_RS07115
uniprot id: T2KK33
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

1347342:BN863 RS01325
gene id: 1347342:BN863_RS01325
uniprot id: T2KGP2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS07255
gene id: 1347342:BN863_RS07255
uniprot id: T2KK57
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1347342:BN863 RS10280
gene id: 1347342:BN863_RS10280
uniprot id: T2KMU1
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1347342:BN863 RS02955
gene id: 1347342:BN863_RS02955
uniprot id: T2KHK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1347342:BN863 RS08600
gene id: 1347342:BN863_RS08600
uniprot id: T2KLU6
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS14795
gene id: 1347342:BN863_RS14795
uniprot id: T2KRL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1347342:BN863 RS17495
gene id: 1347342:BN863_RS17495
uniprot id: T2KR51
names: Similarity
messages: Belongs to the GARS family.

1347342:BN863 RS03415
gene id: 1347342:BN863_RS03415
uniprot id: T2KIX5
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1347342:BN863 RS00450
gene id: 1347342:BN863_RS00450
uniprot id: T2KIM1
names: Similarity
messages: Belongs to the SCO1/2 family.

1347342:BN863 RS11070
gene id: 1347342:BN863_RS11070
uniprot id: T2KN90
names: Cofactor
names: Function
names: Induction
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: By rhamnose.
messages: Periplasm
messages: Sulfatase involved in ulvan degradation (PubMed:31285597). Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall. It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (Probable). The sulfatase desulfates Xyl2S-Rha3S, product of the degradation of ulvan by endo-acting alpha-1,4-L-rhamnosidase, to Xyl-Rha3S (PubMed:31285597).
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1347342:BN863 RS09205
gene id: 1347342:BN863_RS09205
uniprot id: T2KM66
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS03760
gene id: 1347342:BN863_RS03760
uniprot id: T2KJ54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1347342:BN863 RS13975
gene id: 1347342:BN863_RS13975
uniprot id: T2KR70
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1347342:BN863 RS02385
gene id: 1347342:BN863_RS02385
uniprot id: T2KID0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1347342:BN863 RS01365
gene id: 1347342:BN863_RS01365
uniprot id: T2KGS3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS00010
gene id: 1347342:BN863_RS00010
uniprot id: T2KIB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1347342:BN863 RS04790
gene id: 1347342:BN863_RS04790
uniprot id: T2KJP7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1347342:BN863 RS03410
gene id: 1347342:BN863_RS03410
uniprot id: T2KHQ9
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1347342:BN863 RS03175
gene id: 1347342:BN863_RS03175
uniprot id: T2KK41
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1347342:BN863 RS04070
gene id: 1347342:BN863_RS04070
uniprot id: T2KJA2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1347342:BN863 RS17395
gene id: 1347342:BN863_RS17395
uniprot id: T2KR29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1347342:BN863 RS14820
gene id: 1347342:BN863_RS14820
uniprot id: T2KRM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1347342:BN863 RS01420
gene id: 1347342:BN863_RS01420
uniprot id: T2KHT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1347342:BN863 RS06080
gene id: 1347342:BN863_RS06080
uniprot id: T2KJ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1347342:BN863 RS16105
gene id: 1347342:BN863_RS16105
uniprot id: T2KR52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1347342:BN863 RS08160
gene id: 1347342:BN863_RS08160
uniprot id: T2KLM3
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1347342:BN863 RS17505
gene id: 1347342:BN863_RS17505
uniprot id: T2KQT8
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1347342:BN863 RS03665
gene id: 1347342:BN863_RS03665
uniprot id: T2KJ20
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS13795
gene id: 1347342:BN863_RS13795
uniprot id: T2KR43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1347342:BN863 RS14550
gene id: 1347342:BN863_RS14550
uniprot id: T2KQ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1347342:BN863 RS12635
gene id: 1347342:BN863_RS12635
uniprot id: T2KQH2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1347342:BN863 RS05770
gene id: 1347342:BN863_RS05770
uniprot id: T2KJA5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1347342:BN863 RS14890
gene id: 1347342:BN863_RS14890
uniprot id: T2KRN7
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1347342:BN863 RS07090
gene id: 1347342:BN863_RS07090
uniprot id: T2KK29
names: Similarity
messages: Belongs to the threonine synthase family.

1347342:BN863 RS12520
gene id: 1347342:BN863_RS12520
uniprot id: T2KP29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1347342:BN863 RS08305
gene id: 1347342:BN863_RS08305
uniprot id: T2KLP4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1347342:BN863 RS02850
gene id: 1347342:BN863_RS02850
uniprot id: T2KJV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1347342:BN863 RS06685
gene id: 1347342:BN863_RS06685
uniprot id: T2KKR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1347342:BN863 RS02140
gene id: 1347342:BN863_RS02140
uniprot id: T2KI79
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS03160
gene id: 1347342:BN863_RS03160
uniprot id: T2KIV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1347342:BN863 RS17295
gene id: 1347342:BN863_RS17295
uniprot id: T2KR09
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1347342:BN863 RS11755
gene id: 1347342:BN863_RS11755
uniprot id: T2KNM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1347342:BN863 RS00420
gene id: 1347342:BN863_RS00420
uniprot id: T2KHC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1347342:BN863 RS07095
gene id: 1347342:BN863_RS07095
uniprot id: T2KL06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS06175
gene id: 1347342:BN863_RS06175
uniprot id: T2KKI8
names: Similarity
messages: Belongs to the pirin family.

1347342:BN863 RS14215
gene id: 1347342:BN863_RS14215
uniprot id: T2KP66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1347342:BN863 RS08545
gene id: 1347342:BN863_RS08545
uniprot id: T2KKL2
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1347342:BN863 RS11905
gene id: 1347342:BN863_RS11905
uniprot id: T2KMH6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS01505
gene id: 1347342:BN863_RS01505
uniprot id: T2KJ36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1347342:BN863 RS11870
gene id: 1347342:BN863_RS11870
uniprot id: T2KMW7
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1347342:BN863 RS11260
gene id: 1347342:BN863_RS11260
uniprot id: T2KNC9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1347342:BN863 RS02925
gene id: 1347342:BN863_RS02925
uniprot id: T2KJW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1347342:BN863 RS00640
gene id: 1347342:BN863_RS00640
uniprot id: T2KHG9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

1347342:BN863 RS13490
gene id: 1347342:BN863_RS13490
uniprot id: T2KNF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1347342:BN863 RS11410
gene id: 1347342:BN863_RS11410
uniprot id: T2KPT2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1347342:BN863 RS06995
gene id: 1347342:BN863_RS06995
uniprot id: T2KKY6
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1347342:BN863 RS15230
gene id: 1347342:BN863_RS15230
uniprot id: T2KPI6
names: Similarity
messages: Belongs to the SusD family.

1347342:BN863 RS05800
gene id: 1347342:BN863_RS05800
uniprot id: T2KJ03
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS07105
gene id: 1347342:BN863_RS07105
uniprot id: T2KL04
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS07700
gene id: 1347342:BN863_RS07700
uniprot id: T2KMP4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1347342:BN863 RS04125
gene id: 1347342:BN863_RS04125
uniprot id: T2KKI2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1347342:BN863 RS11690
gene id: 1347342:BN863_RS11690
uniprot id: T2KMT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1347342:BN863 RS15080
gene id: 1347342:BN863_RS15080
uniprot id: T2KPE5
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1347342:BN863 RS04430
gene id: 1347342:BN863_RS04430
uniprot id: T2KJI8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1347342:BN863 RS13260
gene id: 1347342:BN863_RS13260
uniprot id: T2KQV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1347342:BN863 RS01295
gene id: 1347342:BN863_RS01295
uniprot id: T2KHR3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1347342:BN863 RS12440
gene id: 1347342:BN863_RS12440
uniprot id: T2KN64
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1347342:BN863 RS02895
gene id: 1347342:BN863_RS02895
uniprot id: T2KIM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1347342:BN863 RS03000
gene id: 1347342:BN863_RS03000
uniprot id: T2KIQ6
names: Similarity
messages: Belongs to the citrate synthase family.

1347342:BN863 RS05675
gene id: 1347342:BN863_RS05675
uniprot id: T2KLH6
names: Similarity
messages: Belongs to the peptidase M1 family.

1347342:BN863 RS09150
gene id: 1347342:BN863_RS09150
uniprot id: T2KLB9
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1347342:BN863 RS06130
gene id: 1347342:BN863_RS06130
uniprot id: T2KJ61
names: Similarity
messages: Belongs to the UPF0173 family.

1347342:BN863 RS11895
gene id: 1347342:BN863_RS11895
uniprot id: T2KMW9
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1347342:BN863 RS08155
gene id: 1347342:BN863_RS08155
uniprot id: T2KKD7
names: Similarity
messages: Belongs to the nitroreductase family.

1347342:BN863 RS15905
gene id: 1347342:BN863_RS15905
uniprot id: T2KQ85
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1347342:BN863 RS07375
gene id: 1347342:BN863_RS07375
uniprot id: T2KK80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1347342:BN863 RS00615
gene id: 1347342:BN863_RS00615
uniprot id: T2KHG5
names: Similarity
messages: Belongs to the UPF0102 family.

1347342:BN863 RS04095
gene id: 1347342:BN863_RS04095
uniprot id: T2KJA6
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1347342:BN863 RS02610
gene id: 1347342:BN863_RS02610
uniprot id: T2KIH8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1347342:BN863 RS01670
gene id: 1347342:BN863_RS01670
uniprot id: T2KGU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1347342:BN863 RS11580
gene id: 1347342:BN863_RS11580
uniprot id: T2KPX3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1347342:BN863 RS01065
gene id: 1347342:BN863_RS01065
uniprot id: T2KGM5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1347342:BN863 RS16735
gene id: 1347342:BN863_RS16735
uniprot id: T2KQN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm

1347342:BN863 RS04470
gene id: 1347342:BN863_RS04470
uniprot id: T2KKQ3
names: Subcellular Location Annotation
messages: Mitochondrion

1347342:BN863 RS15325
gene id: 1347342:BN863_RS15325
uniprot id: T2KQP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L-fucose isomerase family.
messages: Converts the aldose L-fucose into the corresponding ketose L-fuculose.
messages: Cytoplasm

1347342:BN863 RS17185
gene id: 1347342:BN863_RS17185
uniprot id: T2KQM8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1347342:BN863 RS14680
gene id: 1347342:BN863_RS14680
uniprot id: T2KP60
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1347342:BN863 RS04735
gene id: 1347342:BN863_RS04735
uniprot id: T2KJP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1347342:BN863 RS08045
gene id: 1347342:BN863_RS08045
uniprot id: T2KKR1
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS06535
gene id: 1347342:BN863_RS06535
uniprot id: T2KKQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1347342:BN863 RS04400
gene id: 1347342:BN863_RS04400
uniprot id: T2KIE9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1347342:BN863 RS01560
gene id: 1347342:BN863_RS01560
uniprot id: T2KGV9
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

1347342:BN863 RS16065
gene id: 1347342:BN863_RS16065
uniprot id: T2KQX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required for cell division and gliding motility.

1347342:BN863 RS02670
gene id: 1347342:BN863_RS02670
uniprot id: T2KIH7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1347342:BN863 RS02975
gene id: 1347342:BN863_RS02975
uniprot id: T2KIP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1347342:BN863 RS00735
gene id: 1347342:BN863_RS00735
uniprot id: T2KGE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1347342:BN863 RS10520
gene id: 1347342:BN863_RS10520
uniprot id: T2KLR1
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1347342:BN863 RS00680
gene id: 1347342:BN863_RS00680
uniprot id: T2KHG2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1347342:BN863 RS06455
gene id: 1347342:BN863_RS06455
uniprot id: T2KLW0
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

1347342:BN863 RS03245
gene id: 1347342:BN863_RS03245
uniprot id: T2KK36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1347342:BN863 RS17670
gene id: 1347342:BN863_RS17670
uniprot id: T2KR87
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1347342:BN863 RS03770
gene id: 1347342:BN863_RS03770
uniprot id: T2KJ39
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1347342:BN863 RS11930
gene id: 1347342:BN863_RS11930
uniprot id: T2KMI0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1347342:BN863 RS01980
gene id: 1347342:BN863_RS01980
uniprot id: T2KI48
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS13860
gene id: 1347342:BN863_RS13860
uniprot id: T2KPQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

1347342:BN863 RS13195
gene id: 1347342:BN863_RS13195
uniprot id: T2KPH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1347342:BN863 RS02065
gene id: 1347342:BN863_RS02065
uniprot id: T2KI65
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1347342:BN863 RS12160
gene id: 1347342:BN863_RS12160
uniprot id: T2KMM5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1347342:BN863 RS03180
gene id: 1347342:BN863_RS03180
uniprot id: T2KHS1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1347342:BN863 RS00575
gene id: 1347342:BN863_RS00575
uniprot id: T2KGF3
names: Similarity
messages: Belongs to the histone deacetylase family.

1347342:BN863 RS11080
gene id: 1347342:BN863_RS11080
uniprot id: T2KMH9
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family.
messages: By ulvan and rhamnose.
messages: Cell outer membrane
messages: Glycoside hydrolase probably involved in ulvan degradation (Probable). Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall. It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (Probable).

1347342:BN863 RS00505
gene id: 1347342:BN863_RS00505
uniprot id: T2KGE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1347342:BN863 RS10945
gene id: 1347342:BN863_RS10945
uniprot id: T2KN67
names: Function
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: May be involved in ulvan degradation (Probable). Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall. It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (Probable).

1347342:BN863 RS15340
gene id: 1347342:BN863_RS15340
uniprot id: T2KRV6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1347342:BN863 RS14365
gene id: 1347342:BN863_RS14365
uniprot id: T2KP92
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

1347342:BN863 RS07730
gene id: 1347342:BN863_RS07730
uniprot id: T2KKH3
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS06120
gene id: 1347342:BN863_RS06120
uniprot id: T2KJH5
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS01785
gene id: 1347342:BN863_RS01785
uniprot id: T2KJ88
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1347342:BN863 RS17040
gene id: 1347342:BN863_RS17040
uniprot id: T2KRM9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1347342:BN863 RS17010
gene id: 1347342:BN863_RS17010
uniprot id: T2KQU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1347342:BN863 RS16750
gene id: 1347342:BN863_RS16750
uniprot id: T2KRB3
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1347342:BN863 RS10755
gene id: 1347342:BN863_RS10755
uniprot id: T2KLW2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1347342:BN863 RS17035
gene id: 1347342:BN863_RS17035
uniprot id: T2KQU6
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1347342:BN863 RS08535
gene id: 1347342:BN863_RS08535
uniprot id: T2KL11
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1347342:BN863 RS12905
gene id: 1347342:BN863_RS12905
uniprot id: T2KN06
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1347342:BN863 RS02120
gene id: 1347342:BN863_RS02120
uniprot id: T2KH14
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS16230
gene id: 1347342:BN863_RS16230
uniprot id: T2KQ45
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS13455
gene id: 1347342:BN863_RS13455
uniprot id: T2KNT7
names: Similarity
messages: Belongs to the SusD family.

1347342:BN863 RS17415
gene id: 1347342:BN863_RS17415
uniprot id: T2KSC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Membrane

1347342:BN863 RS17280
gene id: 1347342:BN863_RS17280
uniprot id: T2KQP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1347342:BN863 RS17830
gene id: 1347342:BN863_RS17830
uniprot id: T2KRY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1347342:BN863 RS07075
gene id: 1347342:BN863_RS07075
uniprot id: T2KJP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1347342:BN863 RS12265
gene id: 1347342:BN863_RS12265
uniprot id: T2KNY0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1347342:BN863 RS01975
gene id: 1347342:BN863_RS01975
uniprot id: T2KGZ3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1347342:BN863 RS02390
gene id: 1347342:BN863_RS02390
uniprot id: T2KH60
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

1347342:BN863 RS02555
gene id: 1347342:BN863_RS02555
uniprot id: T2KHC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1347342:BN863 RS00190
gene id: 1347342:BN863_RS00190
uniprot id: T2KH73
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS05755
gene id: 1347342:BN863_RS05755
uniprot id: T2KIZ5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1347342:BN863 RS02790
gene id: 1347342:BN863_RS02790
uniprot id: T2KHD1
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1347342:BN863 RS02550
gene id: 1347342:BN863_RS02550
uniprot id: T2KJP5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1347342:BN863 RS10100
gene id: 1347342:BN863_RS10100
uniprot id: T2KLF2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1347342:BN863 RS03815
gene id: 1347342:BN863_RS03815
uniprot id: T2KJ49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COX15/CtaA family. Type 2 subfamily.
messages: Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
messages: Cell membrane
messages: Interacts with CtaB.
messages: Membrane

1347342:BN863 RS15055
gene id: 1347342:BN863_RS15055
uniprot id: T2KPE0
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1347342:BN863 RS01660
gene id: 1347342:BN863_RS01660
uniprot id: T2KGX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1347342:BN863 RS12750
gene id: 1347342:BN863_RS12750
uniprot id: T2KP72
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS07765
gene id: 1347342:BN863_RS07765
uniprot id: T2KK41
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1347342:BN863 RS02715
gene id: 1347342:BN863_RS02715
uniprot id: T2KHC3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1347342:BN863 RS16745
gene id: 1347342:BN863_RS16745
uniprot id: T2KQE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1347342:BN863 RS09835
gene id: 1347342:BN863_RS09835
uniprot id: T2KNW1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1347342:BN863 RS14235
gene id: 1347342:BN863_RS14235
uniprot id: T2KRB6
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1347342:BN863 RS17620
gene id: 1347342:BN863_RS17620
uniprot id: T2KR74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1347342:BN863 RS07660
gene id: 1347342:BN863_RS07660
uniprot id: T2KKF7
names: Similarity
messages: Belongs to the DEAD box helicase family.

1347342:BN863 RS10480
gene id: 1347342:BN863_RS10480
uniprot id: T2KPB0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1347342:BN863 RS16155
gene id: 1347342:BN863_RS16155
uniprot id: T2KR59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1347342:BN863 RS01385
gene id: 1347342:BN863_RS01385
uniprot id: T2KJ18
names: Similarity
messages: Belongs to the Skp family.

1347342:BN863 RS02855
gene id: 1347342:BN863_RS02855
uniprot id: T2KHH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1347342:BN863 RS12020
gene id: 1347342:BN863_RS12020
uniprot id: T2KMY5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1347342:BN863 RS15445
gene id: 1347342:BN863_RS15445
uniprot id: T2KPY9
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1347342:BN863 RS16615
gene id: 1347342:BN863_RS16615
uniprot id: T2KRE8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1347342:BN863 RS17130
gene id: 1347342:BN863_RS17130
uniprot id: T2KRP4
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

1347342:BN863 RS11220
gene id: 1347342:BN863_RS11220
uniprot id: T2KMK3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1347342:BN863 RS10050
gene id: 1347342:BN863_RS10050
uniprot id: T2KMR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1347342:BN863 RS16525
gene id: 1347342:BN863_RS16525
uniprot id: T2KR66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1347342:BN863 RS15035
gene id: 1347342:BN863_RS15035
uniprot id: T2KQD4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1347342:BN863 RS06020
gene id: 1347342:BN863_RS06020
uniprot id: T2KJF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

1347342:BN863 RS09805
gene id: 1347342:BN863_RS09805
uniprot id: T2KMI7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1347342:BN863 RS11005
gene id: 1347342:BN863_RS11005
uniprot id: T2KMG7
names: Cofactor
names: Function
names: Induction
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: By ulvan.
messages: Cell membrane
messages: Sulfatase involved in ulvan degradation (PubMed:31285597). Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall. It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (Probable).
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. This post-translational modification is severely defective in multiple sulfatase deficiency (MSD).

1347342:BN863 RS03140
gene id: 1347342:BN863_RS03140
uniprot id: T2KIU7
names: Similarity
messages: Belongs to the UPF0246 family.

1347342:BN863 RS13835
gene id: 1347342:BN863_RS13835
uniprot id: T2KNL9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS16715
gene id: 1347342:BN863_RS16715
uniprot id: T2KRG3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1347342:BN863 RS15460
gene id: 1347342:BN863_RS15460
uniprot id: T2KQM9
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1347342:BN863 RS12365
gene id: 1347342:BN863_RS12365
uniprot id: T2KMR1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1347342:BN863 RS13595
gene id: 1347342:BN863_RS13595
uniprot id: T2KNW3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1347342:BN863 RS12730
gene id: 1347342:BN863_RS12730
uniprot id: T2KMX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1347342:BN863 RS01235
gene id: 1347342:BN863_RS01235
uniprot id: T2KIZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1347342:BN863 RS07715
gene id: 1347342:BN863_RS07715
uniprot id: T2KK32
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1347342:BN863 RS12425
gene id: 1347342:BN863_RS12425
uniprot id: T2KMR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1347342:BN863 RS02735
gene id: 1347342:BN863_RS02735
uniprot id: T2KIK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1347342:BN863 RS07065
gene id: 1347342:BN863_RS07065
uniprot id: T2KK24
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1347342:BN863 RS03470
gene id: 1347342:BN863_RS03470
uniprot id: T2KK66
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS12295
gene id: 1347342:BN863_RS12295
uniprot id: T2KQB0
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS05710
gene id: 1347342:BN863_RS05710
uniprot id: T2KKA0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1347342:BN863 RS11210
gene id: 1347342:BN863_RS11210
uniprot id: T2KNC1
names: Similarity
messages: Belongs to the ParB family.

1347342:BN863 RS13635
gene id: 1347342:BN863_RS13635
uniprot id: T2KPL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1347342:BN863 RS04880
gene id: 1347342:BN863_RS04880
uniprot id: T2KJS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1347342:BN863 RS04825
gene id: 1347342:BN863_RS04825
uniprot id: T2KIM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1347342:BN863 RS17125
gene id: 1347342:BN863_RS17125
uniprot id: T2KQW7
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1347342:BN863 RS01620
gene id: 1347342:BN863_RS01620
uniprot id: T2KGT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1347342:BN863 RS11610
gene id: 1347342:BN863_RS11610
uniprot id: T2KMS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1347342:BN863 RS16720
gene id: 1347342:BN863_RS16720
uniprot id: T2KQE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1347342:BN863 RS15915
gene id: 1347342:BN863_RS15915
uniprot id: T2KPY6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1347342:BN863 RS13170
gene id: 1347342:BN863_RS13170
uniprot id: T2KPG8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS13350
gene id: 1347342:BN863_RS13350
uniprot id: T2KQW3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1347342:BN863 RS05730
gene id: 1347342:BN863_RS05730
uniprot id: T2KIY9
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS08955
gene id: 1347342:BN863_RS08955
uniprot id: T2KKT6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1347342:BN863 RS09960
gene id: 1347342:BN863_RS09960
uniprot id: T2KNZ3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1347342:BN863 RS17700
gene id: 1347342:BN863_RS17700
uniprot id: T2KRX1
names: Similarity
messages: Belongs to the UPF0145 family.

1347342:BN863 RS15225
gene id: 1347342:BN863_RS15225
uniprot id: T2KQM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1347342:BN863 RS03195
gene id: 1347342:BN863_RS03195
uniprot id: T2KIT8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1347342:BN863 RS06230
gene id: 1347342:BN863_RS06230
uniprot id: T2KJ80
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS11740
gene id: 1347342:BN863_RS11740
uniprot id: T2KMU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

1347342:BN863 RS13020
gene id: 1347342:BN863_RS13020
uniprot id: T2KNL5
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1347342:BN863 RS03340
gene id: 1347342:BN863_RS03340
uniprot id: T2KIW1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1347342:BN863 RS14840
gene id: 1347342:BN863_RS14840
uniprot id: T2KRM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1347342:BN863 RS11065
gene id: 1347342:BN863_RS11065
uniprot id: T2KM23
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Alpha-rhamnosidase involved in ulvan degradation (PubMed:31285597). Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall. It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (Probable). Endo-acting alpha-1,4-L-rhamnosidase cleaves rhamnose sections interspersed between xylose residues within the polymer, degrading larger oligomers with consecutive Xyl-Rha3S units that are resistant to the ulvan lyases and producing dimers Xyl-Rha3S and Xyl2S-Rha3S as the smallest products (PubMed:31285597).
messages: Belongs to the glycosyl hydrolase 39 family.
messages: By ulvan and rhamnose.
messages: Periplasm

1347342:BN863 RS17810
gene id: 1347342:BN863_RS17810
uniprot id: T2KR12
names: Similarity
messages: Belongs to the peptidase S8 family.

1347342:BN863 RS04965
gene id: 1347342:BN863_RS04965
uniprot id: T2KJT1
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1347342:BN863 RS16055
gene id: 1347342:BN863_RS16055
uniprot id: T2KR44
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1347342:BN863 RS11535
gene id: 1347342:BN863_RS11535
uniprot id: T2KMQ7
names: Similarity
names: Subunit
messages: Belongs to the CMP-NeuNAc synthase family.
messages: Belongs to the KdsC family.
messages: Homotetramer.

1347342:BN863 RS00955
gene id: 1347342:BN863_RS00955
uniprot id: T2KHM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1347342:BN863 RS15260
gene id: 1347342:BN863_RS15260
uniprot id: T2KQI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1347342:BN863 RS06070
gene id: 1347342:BN863_RS06070
uniprot id: T2KJG5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1347342:BN863 RS05480
gene id: 1347342:BN863_RS05480
uniprot id: T2KJ23
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1347342:BN863 RS05910
gene id: 1347342:BN863_RS05910
uniprot id: T2KKB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1347342:BN863 RS02890
gene id: 1347342:BN863_RS02890
uniprot id: T2KHE8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1347342:BN863 RS05495
gene id: 1347342:BN863_RS05495
uniprot id: T2KK28
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1347342:BN863 RS05450
gene id: 1347342:BN863_RS05450
uniprot id: T2KLB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1347342:BN863 RS15705
gene id: 1347342:BN863_RS15705
uniprot id: T2KPV2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1347342:BN863 RS02615
gene id: 1347342:BN863_RS02615
uniprot id: T2KHA4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1347342:BN863 RS00195
gene id: 1347342:BN863_RS00195
uniprot id: T2KIF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1347342:BN863 RS03455
gene id: 1347342:BN863_RS03455
uniprot id: T2KJ06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

1347342:BN863 RS11660
gene id: 1347342:BN863_RS11660
uniprot id: T2KPY7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1347342:BN863 RS06195
gene id: 1347342:BN863_RS06195
uniprot id: T2KJI7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1347342:BN863 RS03945
gene id: 1347342:BN863_RS03945
uniprot id: T2KJ73
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS17860
gene id: 1347342:BN863_RS17860
uniprot id: T2KR25
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1347342:BN863 RS07995
gene id: 1347342:BN863_RS07995
uniprot id: T2KLJ8
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS10210
gene id: 1347342:BN863_RS10210
uniprot id: T2KP49
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1347342:BN863 RS01915
gene id: 1347342:BN863_RS01915
uniprot id: T2KH09
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1347342:BN863 RS01950
gene id: 1347342:BN863_RS01950
uniprot id: T2KGY9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1347342:BN863 RS15995
gene id: 1347342:BN863_RS15995
uniprot id: T2KQW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1347342:BN863 RS10135
gene id: 1347342:BN863_RS10135
uniprot id: T2KP34
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS04415
gene id: 1347342:BN863_RS04415
uniprot id: T2KJH1
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1347342:BN863 RS11075
gene id: 1347342:BN863_RS11075
uniprot id: T2KPL9
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 105 family.
messages: By ulvan and rhamnose.
messages: Periplasm
messages: Unsaturated beta-glucuronyl hydrolase involved in ulvan degradation (Ref.2, PubMed:31285597). Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall. It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (Probable). Unsaturated 3S-rhamnoglycuronyl hydrolase works together with ulvan lyases to fully degrade the ulvan polymer, catalyzing specifically the cleavage of the unsaturated 4-deoxy-L-threo-hex-4-enopyranosiduronic acid (deltaUA) of deltaUA-Rha3S disaccharides and deltaUA-Rha3S-Xyl-Rha3S tetrasaccharides, the end products of the ulvan lyase reaction. Also hydrolases deltaUA-Rha3S-IduA-Rha3S and deltaUA-Rha3S-GlcA-Rha3S tetrasaccharidestetrasaccharides. Prefers tetrasaccharides over disaccharides and prefers an uronic residue at subsite +2 (By similarity).

1347342:BN863 RS09135
gene id: 1347342:BN863_RS09135
uniprot id: T2KKW7
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1347342:BN863 RS08030
gene id: 1347342:BN863_RS08030
uniprot id: T2KKB6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1347342:BN863 RS06850
gene id: 1347342:BN863_RS06850
uniprot id: T2KKV6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1347342:BN863 RS17205
gene id: 1347342:BN863_RS17205
uniprot id: T2KRQ3
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1347342:BN863 RS01495
gene id: 1347342:BN863_RS01495
uniprot id: T2KHW2
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1347342:BN863 RS04060
gene id: 1347342:BN863_RS04060
uniprot id: T2KJA7
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1347342:BN863 RS03930
gene id: 1347342:BN863_RS03930
uniprot id: T2KI59
names: Similarity
messages: Belongs to the Fur family.

1347342:BN863 RS07165
gene id: 1347342:BN863_RS07165
uniprot id: T2KL23
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS01765
gene id: 1347342:BN863_RS01765
uniprot id: T2KGZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1347342:BN863 RS12005
gene id: 1347342:BN863_RS12005
uniprot id: T2KMJ0
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS14765
gene id: 1347342:BN863_RS14765
uniprot id: T2KQ79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1347342:BN863 RS15170
gene id: 1347342:BN863_RS15170
uniprot id: T2KPS1
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1347342:BN863 RS16395
gene id: 1347342:BN863_RS16395
uniprot id: T2KRA5
names: Similarity
messages: Belongs to the aspartokinase family.

1347342:BN863 RS06220
gene id: 1347342:BN863_RS06220
uniprot id: T2KJJ3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS12715
gene id: 1347342:BN863_RS12715
uniprot id: T2KQI8
names: Subunit
messages: Monomer.

1347342:BN863 RS14540
gene id: 1347342:BN863_RS14540
uniprot id: T2KRH0
names: Similarity
messages: Belongs to the DEAD box helicase family.

1347342:BN863 RS01120
gene id: 1347342:BN863_RS01120
uniprot id: T2KHM7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1347342:BN863 RS02820
gene id: 1347342:BN863_RS02820
uniprot id: T2KIK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1347342:BN863 RS04900
gene id: 1347342:BN863_RS04900
uniprot id: T2KIP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1347342:BN863 RS04620
gene id: 1347342:BN863_RS04620
uniprot id: T2KJM0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1347342:BN863 RS11865
gene id: 1347342:BN863_RS11865
uniprot id: T2KQ21
names: Similarity
messages: Belongs to the IMPACT family.

1347342:BN863 RS03280
gene id: 1347342:BN863_RS03280
uniprot id: T2KIX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1347342:BN863 RS15125
gene id: 1347342:BN863_RS15125
uniprot id: T2KQK2
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1347342:BN863 RS12165
gene id: 1347342:BN863_RS12165
uniprot id: T2KNW0
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS11135
gene id: 1347342:BN863_RS11135
uniprot id: T2KMI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1347342:BN863 RS09735
gene id: 1347342:BN863_RS09735
uniprot id: T2KNT8
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS06725
gene id: 1347342:BN863_RS06725
uniprot id: T2KKT8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1347342:BN863 RS10445
gene id: 1347342:BN863_RS10445
uniprot id: T2KN04
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1347342:BN863 RS00170
gene id: 1347342:BN863_RS00170
uniprot id: T2KIE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1347342:BN863 RS06305
gene id: 1347342:BN863_RS06305
uniprot id: T2KJ96
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1347342:BN863 RS15210
gene id: 1347342:BN863_RS15210
uniprot id: T2KQG9
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

1347342:BN863 RS05655
gene id: 1347342:BN863_RS05655
uniprot id: T2KJ82
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

1347342:BN863 RS00205
gene id: 1347342:BN863_RS00205
uniprot id: T2KH72
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS01435
gene id: 1347342:BN863_RS01435
uniprot id: T2KJ27
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1347342:BN863 RS03855
gene id: 1347342:BN863_RS03855
uniprot id: T2KI43
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1347342:BN863 RS15615
gene id: 1347342:BN863_RS15615
uniprot id: T2KQX4
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1347342:BN863 RS00840
gene id: 1347342:BN863_RS00840
uniprot id: T2KHI6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1347342:BN863 RS13915
gene id: 1347342:BN863_RS13915
uniprot id: T2KR61
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1347342:BN863 RS02885
gene id: 1347342:BN863_RS02885
uniprot id: T2KIN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1347342:BN863 RS16165
gene id: 1347342:BN863_RS16165
uniprot id: T2KQZ8
names: Caution
names: Function
names: Similarity
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).

1347342:BN863 RS08835
gene id: 1347342:BN863_RS08835
uniprot id: T2KNA9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell membrane

1347342:BN863 RS15450
gene id: 1347342:BN863_RS15450
uniprot id: T2KQT0
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1347342:BN863 RS08325
gene id: 1347342:BN863_RS08325
uniprot id: T2KKH0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1347342:BN863 RS01010
gene id: 1347342:BN863_RS01010
uniprot id: T2KIU9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1347342:BN863 RS07370
gene id: 1347342:BN863_RS07370
uniprot id: T2KMG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1347342:BN863 RS13695
gene id: 1347342:BN863_RS13695
uniprot id: T2KPM3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1347342:BN863 RS17050
gene id: 1347342:BN863_RS17050
uniprot id: T2KRG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase H family.
messages: Binds 2 metal ions per subunit. Manganese or magnesium.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

1347342:BN863 RS00270
gene id: 1347342:BN863_RS00270
uniprot id: T2KIG3
names: Similarity
messages: Belongs to the RecJ family.

1347342:BN863 RS06240
gene id: 1347342:BN863_RS06240
uniprot id: T2KLR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

1347342:BN863 RS08220
gene id: 1347342:BN863_RS08220
uniprot id: T2KMZ9
names: Similarity
messages: Belongs to the nitroreductase family.

1347342:BN863 RS02110
gene id: 1347342:BN863_RS02110
uniprot id: T2KH43
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1347342:BN863 RS11705
gene id: 1347342:BN863_RS11705
uniprot id: T2KNL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1347342:BN863 RS00870
gene id: 1347342:BN863_RS00870
uniprot id: T2KGG4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1347342:BN863 RS16640
gene id: 1347342:BN863_RS16640
uniprot id: T2KRF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1347342:BN863 RS10980
gene id: 1347342:BN863_RS10980
uniprot id: T2KMG4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Periplasm
messages: Sulfatase that may be involved in ulvan degradation (PubMed:31285597). Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall. It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (Probable). Has no activity on different ulvan polymers (PubMed:31285597).
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. This post-translational modification is severely defective in multiple sulfatase deficiency (MSD).

1347342:BN863 RS04215
gene id: 1347342:BN863_RS04215
uniprot id: T2KJD1
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS04560
gene id: 1347342:BN863_RS04560
uniprot id: T2KKS0
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1347342:BN863 RS15205
gene id: 1347342:BN863_RS15205
uniprot id: T2KPH9
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1347342:BN863 RS00770
gene id: 1347342:BN863_RS00770
uniprot id: T2KHI9
names: Similarity
messages: Belongs to the peptidase S41A family.

1347342:BN863 RS03860
gene id: 1347342:BN863_RS03860
uniprot id: T2KJ71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1347342:BN863 RS08565
gene id: 1347342:BN863_RS08565
uniprot id: T2KLX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1347342:BN863 RS00780
gene id: 1347342:BN863_RS00780
uniprot id: T2KGI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1347342:BN863 RS15830
gene id: 1347342:BN863_RS15830
uniprot id: T2KPX2
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1347342:BN863 RS16030
gene id: 1347342:BN863_RS16030
uniprot id: T2KR40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1347342:BN863 RS02500
gene id: 1347342:BN863_RS02500
uniprot id: T2KJN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1347342:BN863 RS17790
gene id: 1347342:BN863_RS17790
uniprot id: T2KRW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1347342:BN863 RS09140
gene id: 1347342:BN863_RS09140
uniprot id: T2KM51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1347342:BN863 RS13965
gene id: 1347342:BN863_RS13965
uniprot id: T2KNQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1347342:BN863 RS01000
gene id: 1347342:BN863_RS01000
uniprot id: T2KGI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1347342:BN863 RS12370
gene id: 1347342:BN863_RS12370
uniprot id: T2KP00
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS17560
gene id: 1347342:BN863_RS17560
uniprot id: T2KRT0
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1347342:BN863 RS11355
gene id: 1347342:BN863_RS11355
uniprot id: T2KM72
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS09365
gene id: 1347342:BN863_RS09365
uniprot id: T2KMB6
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1347342:BN863 RS14930
gene id: 1347342:BN863_RS14930
uniprot id: T2KPA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1347342:BN863 RS06700
gene id: 1347342:BN863_RS06700
uniprot id: T2KKT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1347342:BN863 RS01115
gene id: 1347342:BN863_RS01115
uniprot id: T2KGN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1347342:BN863 RS04080
gene id: 1347342:BN863_RS04080
uniprot id: T2KI89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1347342:BN863 RS12430
gene id: 1347342:BN863_RS12430
uniprot id: T2KP08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1347342:BN863 RS04340
gene id: 1347342:BN863_RS04340
uniprot id: T2KJG0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

1347342:BN863 RS12660
gene id: 1347342:BN863_RS12660
uniprot id: T2KQH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1347342:BN863 RS14880
gene id: 1347342:BN863_RS14880
uniprot id: T2KPA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1347342:BN863 RS12270
gene id: 1347342:BN863_RS12270
uniprot id: T2KQA5
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS04840
gene id: 1347342:BN863_RS04840
uniprot id: T2KJQ6
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

1347342:BN863 RS07890
gene id: 1347342:BN863_RS07890
uniprot id: T2KK65
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS03125
gene id: 1347342:BN863_RS03125
uniprot id: T2KIS7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1347342:BN863 RS17355
gene id: 1347342:BN863_RS17355
uniprot id: T2KQQ6
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1347342:BN863 RS00875
gene id: 1347342:BN863_RS00875
uniprot id: T2KHK9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1347342:BN863 RS02860
gene id: 1347342:BN863_RS02860
uniprot id: T2KIM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1347342:BN863 RS01550
gene id: 1347342:BN863_RS01550
uniprot id: T2KHX1
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1347342:BN863 RS01200
gene id: 1347342:BN863_RS01200
uniprot id: T2KGL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1347342:BN863 RS12445
gene id: 1347342:BN863_RS12445
uniprot id: T2KP19
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1347342:BN863 RS11505
gene id: 1347342:BN863_RS11505
uniprot id: T2KPV4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1347342:BN863 RS15945
gene id: 1347342:BN863_RS15945
uniprot id: T2KQV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1347342:BN863 RS03325
gene id: 1347342:BN863_RS03325
uniprot id: T2KHU8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1347342:BN863 RS13585
gene id: 1347342:BN863_RS13585
uniprot id: T2KPK4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS03235
gene id: 1347342:BN863_RS03235
uniprot id: T2KHN0
names: Similarity
messages: Belongs to the universal stress protein A family.

1347342:BN863 RS01210
gene id: 1347342:BN863_RS01210
uniprot id: T2KIY7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1347342:BN863 RS04505
gene id: 1347342:BN863_RS04505
uniprot id: T2KJI9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1347342:BN863 RS00860
gene id: 1347342:BN863_RS00860
uniprot id: T2KGJ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS18045
gene id: 1347342:BN863_RS18045
uniprot id: T2KMZ3
names: Subunit
messages: Homodimer.

1347342:BN863 RS02180
gene id: 1347342:BN863_RS02180
uniprot id: T2KJH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1347342:BN863 RS01110
gene id: 1347342:BN863_RS01110
uniprot id: T2KIW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1347342:BN863 RS17105
gene id: 1347342:BN863_RS17105
uniprot id: T2KSB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1347342:BN863 RS16485
gene id: 1347342:BN863_RS16485
uniprot id: T2KQJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1347342:BN863 RS02505
gene id: 1347342:BN863_RS02505
uniprot id: T2KHC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1347342:BN863 RS11085
gene id: 1347342:BN863_RS11085
uniprot id: T2KNC8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Gfo/Idh/MocA family.
messages: By ulvan.
messages: Cell surface
messages: Oxidoreductase that may be involved in ulvan degradation (Probable). Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall. It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (Probable).

1347342:BN863 RS09995
gene id: 1347342:BN863_RS09995
uniprot id: T2KLU2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1347342:BN863 RS15545
gene id: 1347342:BN863_RS15545
uniprot id: T2KQ25
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS11770
gene id: 1347342:BN863_RS11770
uniprot id: T2KNP4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1347342:BN863 RS17835
gene id: 1347342:BN863_RS17835
uniprot id: T2KR18
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

1347342:BN863 RS05500
gene id: 1347342:BN863_RS05500
uniprot id: T2KLC9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1347342:BN863 RS10640
gene id: 1347342:BN863_RS10640
uniprot id: T2KMA8
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

1347342:BN863 RS01650
gene id: 1347342:BN863_RS01650
uniprot id: T2KHY8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS06210
gene id: 1347342:BN863_RS06210
uniprot id: T2KKG7
names: Similarity
messages: Belongs to the arginase family.

1347342:BN863 RS02835
gene id: 1347342:BN863_RS02835
uniprot id: T2KIM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1347342:BN863 RS14145
gene id: 1347342:BN863_RS14145
uniprot id: T2KP55
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1347342:BN863 RS03870
gene id: 1347342:BN863_RS03870
uniprot id: T2KJ57
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1347342:BN863 RS01655
gene id: 1347342:BN863_RS01655
uniprot id: T2KJ64
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1347342:BN863 RS04950
gene id: 1347342:BN863_RS04950
uniprot id: T2KIQ0
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1347342:BN863 RS00185
gene id: 1347342:BN863_RS00185
uniprot id: T2KG91
names: Similarity
messages: Belongs to the peptidase S9A family.

1347342:BN863 RS17140
gene id: 1347342:BN863_RS17140
uniprot id: T2KRJ2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1347342:BN863 RS01855
gene id: 1347342:BN863_RS01855
uniprot id: T2KI23
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1347342:BN863 RS17410
gene id: 1347342:BN863_RS17410
uniprot id: T2KRP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1347342:BN863 RS08720
gene id: 1347342:BN863_RS08720
uniprot id: T2KLZ9
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS02640
gene id: 1347342:BN863_RS02640
uniprot id: T2KHA8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1347342:BN863 RS13190
gene id: 1347342:BN863_RS13190
uniprot id: T2KNP7
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

1347342:BN863 RS12200
gene id: 1347342:BN863_RS12200
uniprot id: T2KN22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

1347342:BN863 RS02795
gene id: 1347342:BN863_RS02795
uniprot id: T2KIK4
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS09265
gene id: 1347342:BN863_RS09265
uniprot id: T2KLD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1347342:BN863 RS17635
gene id: 1347342:BN863_RS17635
uniprot id: T2KRU5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1347342:BN863 RS01025
gene id: 1347342:BN863_RS01025
uniprot id: T2KGI8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1347342:BN863 RS11190
gene id: 1347342:BN863_RS11190
uniprot id: T2KPP3
names: Similarity
messages: Belongs to the SCO1/2 family.

1347342:BN863 RS08480
gene id: 1347342:BN863_RS08480
uniprot id: T2KN44
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1347342:BN863 RS17585
gene id: 1347342:BN863_RS17585
uniprot id: T2KRT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1347342:BN863 RS06545
gene id: 1347342:BN863_RS06545
uniprot id: T2KKN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1347342:BN863 RS16140
gene id: 1347342:BN863_RS16140
uniprot id: T2KQZ3
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1347342:BN863 RS05485
gene id: 1347342:BN863_RS05485
uniprot id: T2KK45
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1347342:BN863 RS16240
gene id: 1347342:BN863_RS16240
uniprot id: T2KS54
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1347342:BN863 RS10495
gene id: 1347342:BN863_RS10495
uniprot id: T2KLQ7
names: Similarity
messages: Belongs to the cytochrome P450 family.

1347342:BN863 RS08320
gene id: 1347342:BN863_RS08320
uniprot id: T2KLS7
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1347342:BN863 RS05580
gene id: 1347342:BN863_RS05580
uniprot id: T2KJ67
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1347342:BN863 RS00100
gene id: 1347342:BN863_RS00100
uniprot id: T2KG97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1347342:BN863 RS08235
gene id: 1347342:BN863_RS08235
uniprot id: T2KKF1
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1347342:BN863 RS11955
gene id: 1347342:BN863_RS11955
uniprot id: T2KMI5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1347342:BN863 RS07100
gene id: 1347342:BN863_RS07100
uniprot id: T2KJQ4
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1347342:BN863 RS11225
gene id: 1347342:BN863_RS11225
uniprot id: T2KNF4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1347342:BN863 RS15950
gene id: 1347342:BN863_RS15950
uniprot id: T2KS17
names: Similarity
messages: Belongs to the peptidase M1 family.

1347342:BN863 RS17595
gene id: 1347342:BN863_RS17595
uniprot id: T2KR68
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1347342:BN863 RS15165
gene id: 1347342:BN863_RS15165
uniprot id: T2KRS6
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1347342:BN863 RS11030
gene id: 1347342:BN863_RS11030
uniprot id: T2KMH0
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family.
messages: By ulvan and rhamnose.
messages: Periplasm
messages: Xylosidase involved in ulvan degradation (Ref.2, PubMed:31285597). Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall. It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (Probable). Beta-xylosidase converts Xyl-Rha3S, a product of alpha-L-rhamnosidase acting on Rha-Xyl-Rha3S oligosaccharides, further to Xyl and Rha3S (PubMed:31285597). The enzyme is able to degrade 4-methylumbelliferyl-beta-D-xylopyranoside (MUX) in vitro (Ref.2).

1347342:BN863 RS05765
gene id: 1347342:BN863_RS05765
uniprot id: T2KLI8
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS16060
gene id: 1347342:BN863_RS16060
uniprot id: T2KQ10
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS00910
gene id: 1347342:BN863_RS00910
uniprot id: T2KGJ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1347342:BN863 RS02875
gene id: 1347342:BN863_RS02875
uniprot id: T2KJV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1347342:BN863 RS07555
gene id: 1347342:BN863_RS07555
uniprot id: T2KJZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1347342:BN863 RS04635
gene id: 1347342:BN863_RS04635
uniprot id: T2KKT7
names: Similarity
messages: Belongs to the peptidase C40 family.

1347342:BN863 RS16245
gene id: 1347342:BN863_RS16245
uniprot id: T2KQE8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1347342:BN863 RS09105
gene id: 1347342:BN863_RS09105
uniprot id: T2KM65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1347342:BN863 RS00560
gene id: 1347342:BN863_RS00560
uniprot id: T2KHE4
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

1347342:BN863 RS16300
gene id: 1347342:BN863_RS16300
uniprot id: T2KQ57
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1347342:BN863 RS09915
gene id: 1347342:BN863_RS09915
uniprot id: T2KLS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1347342:BN863 RS04555
gene id: 1347342:BN863_RS04555
uniprot id: T2KJJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1347342:BN863 RS01170
gene id: 1347342:BN863_RS01170
uniprot id: T2KHN7
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

1347342:BN863 RS02810
gene id: 1347342:BN863_RS02810
uniprot id: T2KIL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1347342:BN863 RS10515
gene id: 1347342:BN863_RS10515
uniprot id: T2KN18
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1347342:BN863 RS01255
gene id: 1347342:BN863_RS01255
uniprot id: T2KHR9
names: Similarity
messages: Belongs to the SCO1/2 family.

1347342:BN863 RS03915
gene id: 1347342:BN863_RS03915
uniprot id: T2KHZ9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1347342:BN863 RS16850
gene id: 1347342:BN863_RS16850
uniprot id: T2KRD2
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS10415
gene id: 1347342:BN863_RS10415
uniprot id: T2KM47
names: Similarity
messages: Belongs to the UxaA family.

1347342:BN863 RS11015
gene id: 1347342:BN863_RS11015
uniprot id: T2KM13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the rhamnose mutarotase family.
messages: Cytoplasm
messages: Homodimer.
messages: L-rhamnose mutarotase involved in ulvan degradation (PubMed:31285597). Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall. It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (Probable). L-rhamnose mutarotase catalyzes the anomeric conversion of alpha- to beta-L-rhamnose (PubMed:31285597).

1347342:BN863 RS13625
gene id: 1347342:BN863_RS13625
uniprot id: T2KPP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1347342:BN863 RS04140
gene id: 1347342:BN863_RS04140
uniprot id: T2KJB7
names: Similarity
messages: Belongs to the BshC family.

1347342:BN863 RS03785
gene id: 1347342:BN863_RS03785
uniprot id: T2KJ58
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1347342:BN863 RS11050
gene id: 1347342:BN863_RS11050
uniprot id: T2KPL4
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Alpha-L-rhamnosidase that may be involved in ulvan degradation (Probable). Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall. It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (Probable).
messages: Belongs to the glycosyl hydrolase 78 family.
messages: By ulvan and rhamnose.
messages: Cell membrane

1347342:BN863 RS01775
gene id: 1347342:BN863_RS01775
uniprot id: T2KGV6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS10315
gene id: 1347342:BN863_RS10315
uniprot id: T2KM20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1347342:BN863 RS09900
gene id: 1347342:BN863_RS09900
uniprot id: T2KLB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1347342:BN863 RS16675
gene id: 1347342:BN863_RS16675
uniprot id: T2KR96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

1347342:BN863 RS15075
gene id: 1347342:BN863_RS15075
uniprot id: T2KQJ1
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

1347342:BN863 RS06185
gene id: 1347342:BN863_RS06185
uniprot id: T2KKG1
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS06710
gene id: 1347342:BN863_RS06710
uniprot id: T2KKS4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1347342:BN863 RS13240
gene id: 1347342:BN863_RS13240
uniprot id: T2KNQ4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1347342:BN863 RS13785
gene id: 1347342:BN863_RS13785
uniprot id: T2KPS0
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1347342:BN863 RS12865
gene id: 1347342:BN863_RS12865
uniprot id: T2KQL7
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS09380
gene id: 1347342:BN863_RS09380
uniprot id: T2KMA5
names: Similarity
messages: Belongs to the SusD family.

1347342:BN863 RS12395
gene id: 1347342:BN863_RS12395
uniprot id: T2KP09
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1347342:BN863 RS04190
gene id: 1347342:BN863_RS04190
uniprot id: T2KJC7
names: Similarity
messages: Belongs to the peptidase S8 family.

1347342:BN863 RS17385
gene id: 1347342:BN863_RS17385
uniprot id: T2KRP2
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS01245
gene id: 1347342:BN863_RS01245
uniprot id: T2KHQ3
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS17840
gene id: 1347342:BN863_RS17840
uniprot id: T2KRX2
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1347342:BN863 RS02525
gene id: 1347342:BN863_RS02525
uniprot id: T2KJP1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

1347342:BN863 RS10085
gene id: 1347342:BN863_RS10085
uniprot id: T2KP23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1347342:BN863 RS05750
gene id: 1347342:BN863_RS05750
uniprot id: T2KKB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1347342:BN863 RS15015
gene id: 1347342:BN863_RS15015
uniprot id: T2KRQ4
names: Similarity
messages: Belongs to the polysaccharide lyase 8 family.

1347342:BN863 RS17805
gene id: 1347342:BN863_RS17805
uniprot id: T2KRX8
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1347342:BN863 RS04515
gene id: 1347342:BN863_RS04515
uniprot id: T2KIH0
names: Similarity
messages: Belongs to the HSP15 family.

1347342:BN863 RS08275
gene id: 1347342:BN863_RS08275
uniprot id: T2KLR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1347342:BN863 RS01810
gene id: 1347342:BN863_RS01810
uniprot id: T2KJ93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1347342:BN863 RS06010
gene id: 1347342:BN863_RS06010
uniprot id: T2KKC9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

1347342:BN863 RS16545
gene id: 1347342:BN863_RS16545
uniprot id: T2KQA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1347342:BN863 RS04640
gene id: 1347342:BN863_RS04640
uniprot id: T2KIJ4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1347342:BN863 RS18685
gene id: 1347342:BN863_RS18685
uniprot id: T2KN68
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1347342:BN863 RS01840
gene id: 1347342:BN863_RS01840
uniprot id: T2KH00
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1347342:BN863 RS12315
gene id: 1347342:BN863_RS12315
uniprot id: T2KNY9
names: Similarity
messages: Belongs to the peptidase M16 family.

1347342:BN863 RS06620
gene id: 1347342:BN863_RS06620
uniprot id: T2KKQ1
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-II family.

1347342:BN863 RS13910
gene id: 1347342:BN863_RS13910
uniprot id: T2KPR5
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1347342:BN863 RS13875
gene id: 1347342:BN863_RS13875
uniprot id: T2KPU3
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS11600
gene id: 1347342:BN863_RS11600
uniprot id: T2KNJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1347342:BN863 RS05525
gene id: 1347342:BN863_RS05525
uniprot id: T2KLE3
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS09865
gene id: 1347342:BN863_RS09865
uniprot id: T2KLQ9
names: Subcellular Location Annotation
messages: Secreted

1347342:BN863 RS17175
gene id: 1347342:BN863_RS17175
uniprot id: T2KQY0
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1347342:BN863 RS17800
gene id: 1347342:BN863_RS17800
uniprot id: T2KRB5
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1347342:BN863 RS03795
gene id: 1347342:BN863_RS03795
uniprot id: T2KKB9
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS09710
gene id: 1347342:BN863_RS09710
uniprot id: T2KNT2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS12650
gene id: 1347342:BN863_RS12650
uniprot id: T2KMV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1347342:BN863 RS10685
gene id: 1347342:BN863_RS10685
uniprot id: T2KN27
names: Similarity
messages: Belongs to the SusD family.

1347342:BN863 RS09790
gene id: 1347342:BN863_RS09790
uniprot id: T2KLP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1347342:BN863 RS05335
gene id: 1347342:BN863_RS05335
uniprot id: T2KK14
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1347342:BN863 RS10095
gene id: 1347342:BN863_RS10095
uniprot id: T2KMS4
names: Similarity
messages: Belongs to the Dps family.

1347342:BN863 RS11585
gene id: 1347342:BN863_RS11585
uniprot id: T2KMR7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1347342:BN863 RS05140
gene id: 1347342:BN863_RS05140
uniprot id: T2KIL3
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

1347342:BN863 RS02945
gene id: 1347342:BN863_RS02945
uniprot id: T2KIN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1347342:BN863 RS13155
gene id: 1347342:BN863_RS13155
uniprot id: T2KN96
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1347342:BN863 RS00950
gene id: 1347342:BN863_RS00950
uniprot id: T2KGH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1347342:BN863 RS12225
gene id: 1347342:BN863_RS12225
uniprot id: T2KN25
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1347342:BN863 RS02090
gene id: 1347342:BN863_RS02090
uniprot id: T2KI67
names: Similarity
messages: Belongs to the DNA photolyase family.

1347342:BN863 RS01525
gene id: 1347342:BN863_RS01525
uniprot id: T2KHW6
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

1347342:BN863 RS10750
gene id: 1347342:BN863_RS10750
uniprot id: T2KN59
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1347342:BN863 RS04175
gene id: 1347342:BN863_RS04175
uniprot id: T2KIA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1347342:BN863 RS15765
gene id: 1347342:BN863_RS15765
uniprot id: T2KRZ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1347342:BN863 RS05060
gene id: 1347342:BN863_RS05060
uniprot id: T2KJW0
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1347342:BN863 RS05395
gene id: 1347342:BN863_RS05395
uniprot id: T2KK04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1347342:BN863 RS00550
gene id: 1347342:BN863_RS00550
uniprot id: T2KIN2
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS11625
gene id: 1347342:BN863_RS11625
uniprot id: T2KNK3
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1347342:BN863 RS14860
gene id: 1347342:BN863_RS14860
uniprot id: T2KQA1
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1347342:BN863 RS02830
gene id: 1347342:BN863_RS02830
uniprot id: T2KHH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1347342:BN863 RS16025
gene id: 1347342:BN863_RS16025
uniprot id: T2KQA7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS15245
gene id: 1347342:BN863_RS15245
uniprot id: T2KPT7
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1347342:BN863 RS12340
gene id: 1347342:BN863_RS12340
uniprot id: T2KNZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1347342:BN863 RS15480
gene id: 1347342:BN863_RS15480
uniprot id: T2KPR4
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS01570
gene id: 1347342:BN863_RS01570
uniprot id: T2KGS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1347342:BN863 RS08425
gene id: 1347342:BN863_RS08425
uniprot id: T2KK41
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1347342:BN863 RS04680
gene id: 1347342:BN863_RS04680
uniprot id: T2KJN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1347342:BN863 RS02935
gene id: 1347342:BN863_RS02935
uniprot id: T2KIP4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1347342:BN863 RS11285
gene id: 1347342:BN863_RS11285
uniprot id: T2KND4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1347342:BN863 RS12765
gene id: 1347342:BN863_RS12765
uniprot id: T2KQJ9
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS10665
gene id: 1347342:BN863_RS10665
uniprot id: T2KPE1
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1347342:BN863 RS02910
gene id: 1347342:BN863_RS02910
uniprot id: T2KIN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1347342:BN863 RS10080
gene id: 1347342:BN863_RS10080
uniprot id: T2KMP0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1347342:BN863 RS15885
gene id: 1347342:BN863_RS15885
uniprot id: T2KR16
names: Similarity
messages: Belongs to the thioredoxin family.

1347342:BN863 RS03935
gene id: 1347342:BN863_RS03935
uniprot id: T2KJ87
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1347342:BN863 RS03465
gene id: 1347342:BN863_RS03465
uniprot id: T2KIY4
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1347342:BN863 RS14575
gene id: 1347342:BN863_RS14575
uniprot id: T2KQ86
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

1347342:BN863 RS04850
gene id: 1347342:BN863_RS04850
uniprot id: T2KIN1
names: Similarity
messages: Belongs to the SusD family.

1347342:BN863 RS00300
gene id: 1347342:BN863_RS00300
uniprot id: T2KH94
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS17565
gene id: 1347342:BN863_RS17565
uniprot id: T2KSD4
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1347342:BN863 RS10395
gene id: 1347342:BN863_RS10395
uniprot id: T2KMX6
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1347342:BN863 RS14560
gene id: 1347342:BN863_RS14560
uniprot id: T2KQ32
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS14700
gene id: 1347342:BN863_RS14700
uniprot id: T2KQB1
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

1347342:BN863 RS06580
gene id: 1347342:BN863_RS06580
uniprot id: T2KJR9
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS05535
gene id: 1347342:BN863_RS05535
uniprot id: T2KK75
names: Subcellular Location Annotation
messages: Nucleus

1347342:BN863 RS10620
gene id: 1347342:BN863_RS10620
uniprot id: T2KN40
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1347342:BN863 RS12350
gene id: 1347342:BN863_RS12350
uniprot id: T2KN50
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1347342:BN863 RS14110
gene id: 1347342:BN863_RS14110
uniprot id: T2KPU7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1347342:BN863 RS13570
gene id: 1347342:BN863_RS13570
uniprot id: T2KNV9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS03500
gene id: 1347342:BN863_RS03500
uniprot id: T2KJ16
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1347342:BN863 RS10825
gene id: 1347342:BN863_RS10825
uniprot id: T2KN74
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1347342:BN863 RS06355
gene id: 1347342:BN863_RS06355
uniprot id: T2KJA8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1347342:BN863 RS08450
gene id: 1347342:BN863_RS08450
uniprot id: T2KLR6
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS16585
gene id: 1347342:BN863_RS16585
uniprot id: T2KQL4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1347342:BN863 RS12045
gene id: 1347342:BN863_RS12045
uniprot id: T2KMY8
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1347342:BN863 RS10965
gene id: 1347342:BN863_RS10965
uniprot id: T2KM04
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell membrane
messages: Sulfatase involved in ulvan degradation (PubMed:31285597). Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall. It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (Probable).
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. This post-translational modification is severely defective in multiple sulfatase deficiency (MSD).

1347342:BN863 RS09635
gene id: 1347342:BN863_RS09635
uniprot id: T2KNR7
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1347342:BN863 RS04185
gene id: 1347342:BN863_RS04185
uniprot id: T2KI47
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS06285
gene id: 1347342:BN863_RS06285
uniprot id: T2KKI7
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS00725
gene id: 1347342:BN863_RS00725
uniprot id: T2KGH2
names: Similarity
messages: Belongs to the ribF family.

1347342:BN863 RS02360
gene id: 1347342:BN863_RS02360
uniprot id: T2KIC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1347342:BN863 RS02990
gene id: 1347342:BN863_RS02990
uniprot id: T2KIR8
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1347342:BN863 RS15430
gene id: 1347342:BN863_RS15430
uniprot id: T2KPN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1347342:BN863 RS16570
gene id: 1347342:BN863_RS16570
uniprot id: T2KQA9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1347342:BN863 RS06605
gene id: 1347342:BN863_RS06605
uniprot id: T2KKR6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1347342:BN863 RS11680
gene id: 1347342:BN863_RS11680
uniprot id: T2KNL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1347342:BN863 RS16190
gene id: 1347342:BN863_RS16190
uniprot id: T2KS46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1347342:BN863 RS17150
gene id: 1347342:BN863_RS17150
uniprot id: T2KQX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

1347342:BN863 RS01175
gene id: 1347342:BN863_RS01175
uniprot id: T2KGL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1347342:BN863 RS12555
gene id: 1347342:BN863_RS12555
uniprot id: T2KP27
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS12790
gene id: 1347342:BN863_RS12790
uniprot id: T2KQK4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1347342:BN863 RS07110
gene id: 1347342:BN863_RS07110
uniprot id: T2KM89
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1347342:BN863 RS17785
gene id: 1347342:BN863_RS17785
uniprot id: T2KR06
names: Similarity
messages: Belongs to the peptidase S41A family.

1347342:BN863 RS16565
gene id: 1347342:BN863_RS16565
uniprot id: T2KRE0
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1347342:BN863 RS01925
gene id: 1347342:BN863_RS01925
uniprot id: T2KGY4
names: Similarity
messages: Belongs to the EPSP synthase family.

1347342:BN863 RS06105
gene id: 1347342:BN863_RS06105
uniprot id: T2KJ56
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1347342:BN863 RS12770
gene id: 1347342:BN863_RS12770
uniprot id: T2KND7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1347342:BN863 RS09890
gene id: 1347342:BN863_RS09890
uniprot id: T2KLR5
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1347342:BN863 RS04085
gene id: 1347342:BN863_RS04085
uniprot id: T2KJB2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1347342:BN863 RS14770
gene id: 1347342:BN863_RS14770
uniprot id: T2KRL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1347342:BN863 RS12405
gene id: 1347342:BN863_RS12405
uniprot id: T2KP05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1347342:BN863 RS11780
gene id: 1347342:BN863_RS11780
uniprot id: T2KNN3
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1347342:BN863 RS16410
gene id: 1347342:BN863_RS16410
uniprot id: T2KS71
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1347342:BN863 RS02150
gene id: 1347342:BN863_RS02150
uniprot id: T2KI77
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS10920
gene id: 1347342:BN863_RS10920
uniprot id: T2KN63
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SusD family.
messages: By ulvan and rhamnose.
messages: Cell outer membrane
messages: Polysaccharide-binding protein probably involved in ulvan degradation (Probable). Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall. It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (Probable). The SusD-like protein may mediate ulvan oligomer-binding before transport in the periplasm for further degradation (By similarity).

1347342:BN863 RS13415
gene id: 1347342:BN863_RS13415
uniprot id: T2KND9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

1347342:BN863 RS05700
gene id: 1347342:BN863_RS05700
uniprot id: T2KLI0
names: Similarity
messages: Belongs to the glutamate synthase family.

1347342:BN863 RS01805
gene id: 1347342:BN863_RS01805
uniprot id: T2KI15
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1347342:BN863 RS01630
gene id: 1347342:BN863_RS01630
uniprot id: T2KJ59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1347342:BN863 RS14715
gene id: 1347342:BN863_RS14715
uniprot id: T2KRK5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1347342:BN863 RS07440
gene id: 1347342:BN863_RS07440
uniprot id: T2KL76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1347342:BN863 RS11100
gene id: 1347342:BN863_RS11100
uniprot id: T2KPM5
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SusD family.
messages: By ulvan and rhamnose.
messages: Cell outer membrane
messages: Polysaccharide-binding protein probably involved in ulvan degradation (Probable). Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall. It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (Probable). The SusD-like protein may mediate ulvan oligomer-binding before transport in the periplasm for further degradation (By similarity).

1347342:BN863 RS14835
gene id: 1347342:BN863_RS14835
uniprot id: T2KQ95
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1347342:BN863 RS13770
gene id: 1347342:BN863_RS13770
uniprot id: T2KPP0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1347342:BN863 RS11805
gene id: 1347342:BN863_RS11805
uniprot id: T2KNN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1347342:BN863 RS17180
gene id: 1347342:BN863_RS17180
uniprot id: T2KRQ1
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS17405
gene id: 1347342:BN863_RS17405
uniprot id: T2KQR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1347342:BN863 RS13040
gene id: 1347342:BN863_RS13040
uniprot id: T2KQR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1347342:BN863 RS07845
gene id: 1347342:BN863_RS07845
uniprot id: T2KK54
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Membrane

1347342:BN863 RS02725
gene id: 1347342:BN863_RS02725
uniprot id: T2KJS8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS02210
gene id: 1347342:BN863_RS02210
uniprot id: T2KH63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1347342:BN863 RS10850
gene id: 1347342:BN863_RS10850
uniprot id: T2KN78
names: Similarity
messages: Belongs to the SusD family.

1347342:BN863 RS05620
gene id: 1347342:BN863_RS05620
uniprot id: T2KK63
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1347342:BN863 RS10510
gene id: 1347342:BN863_RS10510
uniprot id: T2KM87
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1347342:BN863 RS16135
gene id: 1347342:BN863_RS16135
uniprot id: T2KQ24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1347342:BN863 RS00765
gene id: 1347342:BN863_RS00765
uniprot id: T2KGF1
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1347342:BN863 RS12495
gene id: 1347342:BN863_RS12495
uniprot id: T2KP24
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1347342:BN863 RS12875
gene id: 1347342:BN863_RS12875
uniprot id: T2KP97
names: Similarity
messages: Belongs to the AHA1 family.

1347342:BN863 RS10635
gene id: 1347342:BN863_RS10635
uniprot id: T2KPD7
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1347342:BN863 RS03120
gene id: 1347342:BN863_RS03120
uniprot id: T2KHL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1347342:BN863 RS07445
gene id: 1347342:BN863_RS07445
uniprot id: T2KMI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1347342:BN863 RS14790
gene id: 1347342:BN863_RS14790
uniprot id: T2KQ84
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS04170
gene id: 1347342:BN863_RS04170
uniprot id: T2KKJ3
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS04425
gene id: 1347342:BN863_RS04425
uniprot id: T2KIF5
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS06565
gene id: 1347342:BN863_RS06565
uniprot id: T2KJE5
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1347342:BN863 RS00620
gene id: 1347342:BN863_RS00620
uniprot id: T2KIP3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1347342:BN863 RS17090
gene id: 1347342:BN863_RS17090
uniprot id: T2KRN5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1347342:BN863 RS13025
gene id: 1347342:BN863_RS13025
uniprot id: T2KPD9
names: Similarity
messages: Belongs to the peptidase S24 family.

1347342:BN863 RS06960
gene id: 1347342:BN863_RS06960
uniprot id: T2KM62
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1347342:BN863 RS05745
gene id: 1347342:BN863_RS05745
uniprot id: T2KJA0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1347342:BN863 RS12060
gene id: 1347342:BN863_RS12060
uniprot id: T2KNU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1347342:BN863 RS12400
gene id: 1347342:BN863_RS12400
uniprot id: T2KMR6
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

1347342:BN863 RS12040
gene id: 1347342:BN863_RS12040
uniprot id: T2KQ53
names: Similarity
messages: Belongs to the glycosyl hydrolase 63 family.

1347342:BN863 RS02455
gene id: 1347342:BN863_RS02455
uniprot id: T2KHB2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1347342:BN863 RS16445
gene id: 1347342:BN863_RS16445
uniprot id: T2KQ87
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1347342:BN863 RS17580
gene id: 1347342:BN863_RS17580
uniprot id: T2KQV7
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1347342:BN863 RS16520
gene id: 1347342:BN863_RS16520
uniprot id: T2KQA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1347342:BN863 RS13740
gene id: 1347342:BN863_RS13740
uniprot id: T2KNK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1347342:BN863 RS06280
gene id: 1347342:BN863_RS06280
uniprot id: T2KJ92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Membrane

1347342:BN863 RS05025
gene id: 1347342:BN863_RS05025
uniprot id: T2KL24
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1347342:BN863 RS15265
gene id: 1347342:BN863_RS15265
uniprot id: T2KRU3
names: Similarity
messages: Belongs to the peptidase S13 family.

1347342:BN863 RS01745
gene id: 1347342:BN863_RS01745
uniprot id: T2KHZ7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1347342:BN863 RS06485
gene id: 1347342:BN863_RS06485
uniprot id: T2KJP3
names: Similarity
messages: Belongs to the peptidase C56 family.

1347342:BN863 RS12490
gene id: 1347342:BN863_RS12490
uniprot id: T2KN70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1347342:BN863 RS16875
gene id: 1347342:BN863_RS16875
uniprot id: T2KRD6
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS01105
gene id: 1347342:BN863_RS01105
uniprot id: T2KHP4
names: Similarity
messages: Belongs to the universal stress protein A family.

1347342:BN863 RS07420
gene id: 1347342:BN863_RS07420
uniprot id: T2KMH4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1347342:BN863 RS14685
gene id: 1347342:BN863_RS14685
uniprot id: T2KQ60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1347342:BN863 RS10240
gene id: 1347342:BN863_RS10240
uniprot id: T2KM06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1347342:BN863 RS08990
gene id: 1347342:BN863_RS08990
uniprot id: T2KM19
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1347342:BN863 RS12435
gene id: 1347342:BN863_RS12435
uniprot id: T2KQD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1347342:BN863 RS10780
gene id: 1347342:BN863_RS10780
uniprot id: T2KLW7
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1347342:BN863 RS02425
gene id: 1347342:BN863_RS02425
uniprot id: T2KJM1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS11035
gene id: 1347342:BN863_RS11035
uniprot id: T2KNB8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SusD family.
messages: By ulvan and rhamnose.
messages: Cell outer membrane
messages: Polysaccharide-binding protein probably involved in ulvan degradation (Probable). Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall. It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (Probable). The SusD-like protein may mediate ulvan oligomer-binding before transport in the periplasm for further degradation (By similarity).

1347342:BN863 RS16175
gene id: 1347342:BN863_RS16175
uniprot id: T2KQD5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1347342:BN863 RS00740
gene id: 1347342:BN863_RS00740
uniprot id: T2KHI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1347342:BN863 RS01735
gene id: 1347342:BN863_RS01735
uniprot id: T2KJ78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1347342:BN863 RS15395
gene id: 1347342:BN863_RS15395
uniprot id: T2KPX6
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

1347342:BN863 RS00975
gene id: 1347342:BN863_RS00975
uniprot id: T2KGH9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1347342:BN863 RS05315
gene id: 1347342:BN863_RS05315
uniprot id: T2KIP2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

1347342:BN863 RS10960
gene id: 1347342:BN863_RS10960
uniprot id: T2KNA3
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase family.
messages: By ulvan and rhamnose.
messages: Cell surface
messages: Periplasm
messages: Ulvan lyase involved in ulvan degradation (PubMed:31285597). Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall. It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (Probable). Ulvan lyase catalyzes the endolytic cleavage of the glycosidic bond between Rha3S and the uronic acids GlcA or IduA, producing oligosaccharides that have unsaturated 4-deoxy-L-threo-hex-4-enopyranosiduronic acid (deltaUA) at the non-reducing end. This results eventually in the degradation of the ulvan polysaccharide into deltaUA-Rha3S disaccharides and deltaUA-Rha3S-Xyl-Rha3S tetrasaccharides (PubMed:31285597).

1347342:BN863 RS12220
gene id: 1347342:BN863_RS12220
uniprot id: T2KQ93
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1347342:BN863 RS02515
gene id: 1347342:BN863_RS02515
uniprot id: T2KH85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1347342:BN863 RS01180
gene id: 1347342:BN863_RS01180
uniprot id: T2KHQ6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1347342:BN863 RS17345
gene id: 1347342:BN863_RS17345
uniprot id: T2KR20
names: Similarity
messages: Belongs to the DprA/Smf family.

1347342:BN863 RS10970
gene id: 1347342:BN863_RS10970
uniprot id: T2KN71
names: Cofactor
names: Function
names: Induction
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: By rhamnose.
messages: Periplasm
messages: Sulfatase involved in ulvan degradation (PubMed:31285597). Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall. It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (Probable).
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. This post-translational modification is severely defective in multiple sulfatase deficiency (MSD).

1347342:BN863 RS01830
gene id: 1347342:BN863_RS01830
uniprot id: T2KI19
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1347342:BN863 RS16855
gene id: 1347342:BN863_RS16855
uniprot id: T2KSA5
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

1347342:BN863 RS17675
gene id: 1347342:BN863_RS17675
uniprot id: T2KRW8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1347342:BN863 RS09725
gene id: 1347342:BN863_RS09725
uniprot id: T2KL83
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1347342:BN863 RS12170
gene id: 1347342:BN863_RS12170
uniprot id: T2KQ83
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1347342:BN863 RS01910
gene id: 1347342:BN863_RS01910
uniprot id: T2KJB5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1347342:BN863 RS06160
gene id: 1347342:BN863_RS06160
uniprot id: T2KKF6
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS10220
gene id: 1347342:BN863_RS10220
uniprot id: T2KMU9
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1347342:BN863 RS01835
gene id: 1347342:BN863_RS01835
uniprot id: T2KJA1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS08790
gene id: 1347342:BN863_RS08790
uniprot id: T2KL56
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS10140
gene id: 1347342:BN863_RS10140
uniprot id: T2KLY2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

1347342:BN863 RS02915
gene id: 1347342:BN863_RS02915
uniprot id: T2KHF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1347342:BN863 RS08580
gene id: 1347342:BN863_RS08580
uniprot id: T2KN61
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1347342:BN863 RS04390
gene id: 1347342:BN863_RS04390
uniprot id: T2KJG7
names: Similarity
messages: Belongs to the CarB family.

1347342:BN863 RS03380
gene id: 1347342:BN863_RS03380
uniprot id: T2KIZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1347342:BN863 RS02770
gene id: 1347342:BN863_RS02770
uniprot id: T2KIK0
names: Similarity
messages: Belongs to the UPF0758 family.

1347342:BN863 RS12025
gene id: 1347342:BN863_RS12025
uniprot id: T2KNU4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1347342:BN863 RS06555
gene id: 1347342:BN863_RS06555
uniprot id: T2KJR4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1347342:BN863 RS04925
gene id: 1347342:BN863_RS04925
uniprot id: T2KIP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1347342:BN863 RS01890
gene id: 1347342:BN863_RS01890
uniprot id: T2KH05
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1347342:BN863 RS00440
gene id: 1347342:BN863_RS00440
uniprot id: T2KGC3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1347342:BN863 RS14695
gene id: 1347342:BN863_RS14695
uniprot id: T2KPG7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1347342:BN863 RS00995
gene id: 1347342:BN863_RS00995
uniprot id: T2KHK7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS04030
gene id: 1347342:BN863_RS04030
uniprot id: T2KI78
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

1347342:BN863 RS14950
gene id: 1347342:BN863_RS14950
uniprot id: T2KPM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1347342:BN863 RS11735
gene id: 1347342:BN863_RS11735
uniprot id: T2KPZ8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1347342:BN863 RS01625
gene id: 1347342:BN863_RS01625
uniprot id: T2KHY3
names: Similarity
messages: Belongs to the P(II) protein family.

1347342:BN863 RS06125
gene id: 1347342:BN863_RS06125
uniprot id: T2KKH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1347342:BN863 RS08515
gene id: 1347342:BN863_RS08515
uniprot id: T2KLW4
names: Similarity
messages: Belongs to the RutC family.

1347342:BN863 RS04405
gene id: 1347342:BN863_RS04405
uniprot id: T2KJI3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1347342:BN863 RS09755
gene id: 1347342:BN863_RS09755
uniprot id: T2KMH7
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1347342:BN863 RS06075
gene id: 1347342:BN863_RS06075
uniprot id: T2KKG9
names: Similarity
messages: Belongs to the Fur family.

1347342:BN863 RS03925
gene id: 1347342:BN863_RS03925
uniprot id: T2KKE5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1347342:BN863 RS04150
gene id: 1347342:BN863_RS04150
uniprot id: T2KIA2
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1347342:BN863 RS09845
gene id: 1347342:BN863_RS09845
uniprot id: T2KMM4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1347342:BN863 RS16790
gene id: 1347342:BN863_RS16790
uniprot id: T2KRH7
names: Similarity
messages: Belongs to the threonine aldolase family.

1347342:BN863 RS12300
gene id: 1347342:BN863_RS12300
uniprot id: T2KN42
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1347342:BN863 RS14255
gene id: 1347342:BN863_RS14255
uniprot id: T2KPX4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1347342:BN863 RS02905
gene id: 1347342:BN863_RS02905
uniprot id: T2KHI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1347342:BN863 RS01195
gene id: 1347342:BN863_RS01195
uniprot id: T2KHP3
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1347342:BN863 RS13935
gene id: 1347342:BN863_RS13935
uniprot id: T2KPR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1347342:BN863 RS01355
gene id: 1347342:BN863_RS01355
uniprot id: T2KHT7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS04710
gene id: 1347342:BN863_RS04710
uniprot id: T2KJN9
names: Similarity
messages: Belongs to the SusD family.

1347342:BN863 RS07505
gene id: 1347342:BN863_RS07505
uniprot id: T2KL92
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1347342:BN863 RS14800
gene id: 1347342:BN863_RS14800
uniprot id: T2KPJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1347342:BN863 RS11185
gene id: 1347342:BN863_RS11185
uniprot id: T2KNB6
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS01055
gene id: 1347342:BN863_RS01055
uniprot id: T2KHN6
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1347342:BN863 RS02930
gene id: 1347342:BN863_RS02930
uniprot id: T2KHJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1347342:BN863 RS00095
gene id: 1347342:BN863_RS00095
uniprot id: T2KIC7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

1347342:BN863 RS02565
gene id: 1347342:BN863_RS02565
uniprot id: T2KH95
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1347342:BN863 RS14070
gene id: 1347342:BN863_RS14070
uniprot id: T2KP41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1347342:BN863 RS11200
gene id: 1347342:BN863_RS11200
uniprot id: T2KNE9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the multicopper oxidase family.
messages: Homotrimer.
messages: Periplasm

1347342:BN863 RS16915
gene id: 1347342:BN863_RS16915
uniprot id: T2KRK3
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS15580
gene id: 1347342:BN863_RS15580
uniprot id: T2KRY5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1347342:BN863 RS07560
gene id: 1347342:BN863_RS07560
uniprot id: T2KLA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1347342:BN863 RS08520
gene id: 1347342:BN863_RS08520
uniprot id: T2KKK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

1347342:BN863 RS08640
gene id: 1347342:BN863_RS08640
uniprot id: T2KL27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1347342:BN863 RS07450
gene id: 1347342:BN863_RS07450
uniprot id: T2KK99
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1347342:BN863 RS07460
gene id: 1347342:BN863_RS07460
uniprot id: T2KJX8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS02200
gene id: 1347342:BN863_RS02200
uniprot id: T2KI85
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1347342:BN863 RS02175
gene id: 1347342:BN863_RS02175
uniprot id: T2KI84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1347342:BN863 RS09280
gene id: 1347342:BN863_RS09280
uniprot id: T2KM77
names: Similarity
messages: Belongs to the pirin family.

1347342:BN863 RS14090
gene id: 1347342:BN863_RS14090
uniprot id: T2KR88
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1347342:BN863 RS09560
gene id: 1347342:BN863_RS09560
uniprot id: T2KNQ3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1347342:BN863 RS08375
gene id: 1347342:BN863_RS08375
uniprot id: T2KKI0
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1347342:BN863 RS00565
gene id: 1347342:BN863_RS00565
uniprot id: T2KHF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1347342:BN863 RS16425
gene id: 1347342:BN863_RS16425
uniprot id: T2KR50
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1347342:BN863 RS18880
gene id: 1347342:BN863_RS18880
uniprot id: T2KS79
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS10930
gene id: 1347342:BN863_RS10930
uniprot id: T2KMF4
names: Function
names: PTM
names: Subcellular Location Annotation
messages: Autophosphorylated. Activation requires a sequential transfer of a phosphate group from a His in the primary transmitter domain, to an Asp in the receiver domain and to a His in the secondary transmitter domain.
messages: Cell surface
messages: Histidine kinase probably involved in ulvan degradation (Probable). Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall. It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (Probable).
messages: Membrane

1347342:BN863 RS17400
gene id: 1347342:BN863_RS17400
uniprot id: T2KRT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1347342:BN863 RS04700
gene id: 1347342:BN863_RS04700
uniprot id: T2KIK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1347342:BN863 RS01285
gene id: 1347342:BN863_RS01285
uniprot id: T2KJ01
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1347342:BN863 RS08395
gene id: 1347342:BN863_RS08395
uniprot id: T2KKI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1347342:BN863 RS14785
gene id: 1347342:BN863_RS14785
uniprot id: T2KP80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS01280
gene id: 1347342:BN863_RS01280
uniprot id: T2KHS4
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS14545
gene id: 1347342:BN863_RS14545
uniprot id: T2KPD0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1347342:BN863 RS00150
gene id: 1347342:BN863_RS00150
uniprot id: T2KGA5
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1347342:BN863 RS11720
gene id: 1347342:BN863_RS11720
uniprot id: T2KNN6
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1347342:BN863 RS02980
gene id: 1347342:BN863_RS02980
uniprot id: T2KJY2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1347342:BN863 RS11350
gene id: 1347342:BN863_RS11350
uniprot id: T2KNH8
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS13790
gene id: 1347342:BN863_RS13790
uniprot id: T2KNK9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1347342:BN863 RS02720
gene id: 1347342:BN863_RS02720
uniprot id: T2KII7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1347342:BN863 RS10545
gene id: 1347342:BN863_RS10545
uniprot id: T2KN05
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1347342:BN863 RS02900
gene id: 1347342:BN863_RS02900
uniprot id: T2KJW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1347342:BN863 RS15910
gene id: 1347342:BN863_RS15910
uniprot id: T2KR21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

1347342:BN863 RS01780
gene id: 1347342:BN863_RS01780
uniprot id: T2KI10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1347342:BN863 RS02430
gene id: 1347342:BN863_RS02430
uniprot id: T2KHA9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1347342:BN863 RS16990
gene id: 1347342:BN863_RS16990
uniprot id: T2KRM1
names: Similarity
messages: Belongs to the YciI family.

1347342:BN863 RS12510
gene id: 1347342:BN863_RS12510
uniprot id: T2KQE5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1347342:BN863 RS16600
gene id: 1347342:BN863_RS16600
uniprot id: T2KR81
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1347342:BN863 RS12205
gene id: 1347342:BN863_RS12205
uniprot id: T2KNX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1347342:BN863 RS09875
gene id: 1347342:BN863_RS09875
uniprot id: T2KK41
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1347342:BN863 RS01850
gene id: 1347342:BN863_RS01850
uniprot id: T2KGX1
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1347342:BN863 RS03820
gene id: 1347342:BN863_RS03820
uniprot id: T2KKC4
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1347342:BN863 RS11950
gene id: 1347342:BN863_RS11950
uniprot id: T2KNT3
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1347342:BN863 RS08280
gene id: 1347342:BN863_RS08280
uniprot id: T2KKF9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS14200
gene id: 1347342:BN863_RS14200
uniprot id: T2KNU7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1347342:BN863 RS13580
gene id: 1347342:BN863_RS13580
uniprot id: T2KNH7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1347342:BN863 RS01540
gene id: 1347342:BN863_RS01540
uniprot id: T2KHV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1347342:BN863 RS10890
gene id: 1347342:BN863_RS10890
uniprot id: T2KLY7
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1347342:BN863 RS00145
gene id: 1347342:BN863_RS00145
uniprot id: T2KID7
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1347342:BN863 RS08635
gene id: 1347342:BN863_RS08635
uniprot id: T2KN72
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1347342:BN863 RS11250
gene id: 1347342:BN863_RS11250
uniprot id: T2KNF9
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS08190
gene id: 1347342:BN863_RS08190
uniprot id: T2KLM5
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1347342:BN863 RS01665
gene id: 1347342:BN863_RS01665
uniprot id: T2KHY2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS02510
gene id: 1347342:BN863_RS02510
uniprot id: T2KIF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1347342:BN863 RS07415
gene id: 1347342:BN863_RS07415
uniprot id: T2KL72
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1347342:BN863 RS07275
gene id: 1347342:BN863_RS07275
uniprot id: T2KK62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1347342:BN863 RS05735
gene id: 1347342:BN863_RS05735
uniprot id: T2KK82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1347342:BN863 RS13615
gene id: 1347342:BN863_RS13615
uniprot id: T2KR15
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS16965
gene id: 1347342:BN863_RS16965
uniprot id: T2KRL6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1347342:BN863 RS07530
gene id: 1347342:BN863_RS07530
uniprot id: T2KJZ1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1347342:BN863 RS10940
gene id: 1347342:BN863_RS10940
uniprot id: T2KLZ8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase involved in ulvan degradation (Probable). Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall. It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (Probable). Catalyzes the reversible reduction of 2,5-diketo-3-deoxygluconate (DKII or 4,6-dihydroxy-2,5-dioxohexanoate) into 2-keto-3-deoxygluconate (KDG or 2-dehydro-3-deoxygluconate) with a concomitant oxidation of NADH (By similarity).
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: By ulvan and rhamnose.
messages: Cytoplasm
messages: Homotetramer.

1347342:BN863 RS03955
gene id: 1347342:BN863_RS03955
uniprot id: T2KI64
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1347342:BN863 RS10485
gene id: 1347342:BN863_RS10485
uniprot id: T2KM81
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1347342:BN863 RS07385
gene id: 1347342:BN863_RS07385
uniprot id: T2KJW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1347342:BN863 RS03940
gene id: 1347342:BN863_RS03940
uniprot id: T2KI04
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-53 and Arg-56) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1347342:BN863 RS04000
gene id: 1347342:BN863_RS04000
uniprot id: T2KKG2
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS12690
gene id: 1347342:BN863_RS12690
uniprot id: T2KNB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1347342:BN863 RS08575
gene id: 1347342:BN863_RS08575
uniprot id: T2KLU0
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1347342:BN863 RS06595
gene id: 1347342:BN863_RS06595
uniprot id: T2KKP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1347342:BN863 RS02285
gene id: 1347342:BN863_RS02285
uniprot id: T2KH80
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1347342:BN863 RS07625
gene id: 1347342:BN863_RS07625
uniprot id: T2KLC0
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1347342:BN863 RS02145
gene id: 1347342:BN863_RS02145
uniprot id: T2KH16
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1347342:BN863 RS02295
gene id: 1347342:BN863_RS02295
uniprot id: T2KH42
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1347342:BN863 RS18050
gene id: 1347342:BN863_RS18050
uniprot id: T2KPH5
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1347342:BN863 RS11470
gene id: 1347342:BN863_RS11470
uniprot id: T2KM95
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1347342:BN863 RS10915
gene id: 1347342:BN863_RS10915
uniprot id: T2KLZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 88 family.
messages: Cell surface
messages: Unsaturated glucuronyl hydrolase involved in ulvan degradation (PubMed:31285597). Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall. It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (Probable). Unsaturated glucuronyl hydrolase catalyzes the cleavage of the unsaturated 4-deoxy-L-threo-hex-4-enopyranosiduronic acid (deltaUA) at the non-reducing end of ulvan oligomers, thus forming 5-dehydro-4-deoxy-D-glucuronate (PubMed:31285597).

1347342:BN863 RS01275
gene id: 1347342:BN863_RS01275
uniprot id: T2KGN1
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS07280
gene id: 1347342:BN863_RS07280
uniprot id: T2KL48
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1347342:BN863 RS07430
gene id: 1347342:BN863_RS07430
uniprot id: T2KL75
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS11925
gene id: 1347342:BN863_RS11925
uniprot id: T2KNS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1347342:BN863 RS08250
gene id: 1347342:BN863_RS08250
uniprot id: T2KKU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

1347342:BN863 RS04775
gene id: 1347342:BN863_RS04775
uniprot id: T2KIL5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

1347342:BN863 RS03155
gene id: 1347342:BN863_RS03155
uniprot id: T2KHR8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1347342:BN863 RS06885
gene id: 1347342:BN863_RS06885
uniprot id: T2KJY9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

1347342:BN863 RS16815
gene id: 1347342:BN863_RS16815
uniprot id: T2KRI2
names: Similarity
messages: Belongs to the ArsC family.

1347342:BN863 RS15470
gene id: 1347342:BN863_RS15470
uniprot id: T2KQ03
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1347342:BN863 RS00940
gene id: 1347342:BN863_RS00940
uniprot id: T2KGK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1347342:BN863 RS16440
gene id: 1347342:BN863_RS16440
uniprot id: T2KRB4
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1347342:BN863 RS01690
gene id: 1347342:BN863_RS01690
uniprot id: T2KGX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1347342:BN863 RS01865
gene id: 1347342:BN863_RS01865
uniprot id: T2KH03
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1347342:BN863 RS10540
gene id: 1347342:BN863_RS10540
uniprot id: T2KLR9
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1347342:BN863 RS12415
gene id: 1347342:BN863_RS12415
uniprot id: T2KN58
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1347342:BN863 RS09610
gene id: 1347342:BN863_RS09610
uniprot id: T2KNR1
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1347342:BN863 RS01410
gene id: 1347342:BN863_RS01410
uniprot id: T2KJ22
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1347342:BN863 RS08380
gene id: 1347342:BN863_RS08380
uniprot id: T2KLQ5
names: Similarity
messages: Belongs to the SUI1 family.

1347342:BN863 RS02365
gene id: 1347342:BN863_RS02365
uniprot id: T2KH55
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS07565
gene id: 1347342:BN863_RS07565
uniprot id: T2KML5
names: Subcellular Location Annotation
messages: Membrane

1347342:BN863 RS13900
gene id: 1347342:BN863_RS13900
uniprot id: T2KPU8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1347342:BN863 RS05545
gene id: 1347342:BN863_RS05545
uniprot id: T2KK52
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1347342:BN863 RS03210
gene id: 1347342:BN863_RS03210
uniprot id: T2KIW0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1347342:BN863 RS15925
gene id: 1347342:BN863_RS15925
uniprot id: T2KK41
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.