1345695:CLSA RS11760
gene id: 1345695:CLSA_RS11760
uniprot id: U5MVG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1345695:CLSA RS11365
gene id: 1345695:CLSA_RS11365
uniprot id: U5MR90
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1345695:CLSA RS02605
gene id: 1345695:CLSA_RS02605
uniprot id: U5ML77
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1345695:CLSA RS02265
gene id: 1345695:CLSA_RS02265
uniprot id: U5ML29
names: Similarity
messages: Belongs to the peptidase U62 family.

1345695:CLSA RS14770
gene id: 1345695:CLSA_RS14770
uniprot id: U5MTX7
names: Function
names: Similarity
messages: Belongs to the V-ATPase F subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1345695:CLSA RS15140
gene id: 1345695:CLSA_RS15140
uniprot id: U5MXD9
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

1345695:CLSA RS11640
gene id: 1345695:CLSA_RS11640
uniprot id: U5MVD6
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS06060
gene id: 1345695:CLSA_RS06060
uniprot id: U5MRE7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS05845
gene id: 1345695:CLSA_RS05845
uniprot id: U5MRY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS00205
gene id: 1345695:CLSA_RS00205
uniprot id: U5MJX6
names: Caution
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS19595
gene id: 1345695:CLSA_RS19595
uniprot id: U5MWR6
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1345695:CLSA RS15490
gene id: 1345695:CLSA_RS15490
uniprot id: U5MUI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1345695:CLSA RS16375
gene id: 1345695:CLSA_RS16375
uniprot id: U5MUE6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1345695:CLSA RS02270
gene id: 1345695:CLSA_RS02270
uniprot id: U5MLM5
names: Similarity
messages: Belongs to the peptidase U62 family.

1345695:CLSA RS01780
gene id: 1345695:CLSA_RS01780
uniprot id: U5MLG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1345695:CLSA RS12705
gene id: 1345695:CLSA_RS12705
uniprot id: U5MVD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

1345695:CLSA RS01910
gene id: 1345695:CLSA_RS01910
uniprot id: U5MP64
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1345695:CLSA RS00500
gene id: 1345695:CLSA_RS00500
uniprot id: U5MKW4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1345695:CLSA RS09470
gene id: 1345695:CLSA_RS09470
uniprot id: U5MU46
names: Similarity
messages: Belongs to the mannitol dehydrogenase family. UxaB subfamily.

1345695:CLSA RS07025
gene id: 1345695:CLSA_RS07025
uniprot id: U5MPL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1345695:CLSA RS15115
gene id: 1345695:CLSA_RS15115
uniprot id: U5MXD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1345695:CLSA RS10005
gene id: 1345695:CLSA_RS10005
uniprot id: U5MR25
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS06080
gene id: 1345695:CLSA_RS06080
uniprot id: U5MNS9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1345695:CLSA RS05585
gene id: 1345695:CLSA_RS05585
uniprot id: U5MR47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1345695:CLSA RS03785
gene id: 1345695:CLSA_RS03785
uniprot id: U5MLV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1345695:CLSA RS00520
gene id: 1345695:CLSA_RS00520
uniprot id: U5MP08
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

1345695:CLSA RS12940
gene id: 1345695:CLSA_RS12940
uniprot id: U5MST9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1345695:CLSA RS00375
gene id: 1345695:CLSA_RS00375
uniprot id: U5MK10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

1345695:CLSA RS03600
gene id: 1345695:CLSA_RS03600
uniprot id: U5MPY7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1345695:CLSA RS04530
gene id: 1345695:CLSA_RS04530
uniprot id: U5MMZ7
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1345695:CLSA RS04295
gene id: 1345695:CLSA_RS04295
uniprot id: U5MN29
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1345695:CLSA RS00945
gene id: 1345695:CLSA_RS00945
uniprot id: U5MNH5
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1345695:CLSA RS20930
gene id: 1345695:CLSA_RS20930
uniprot id: U5MWX9
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1345695:CLSA RS11335
gene id: 1345695:CLSA_RS11335
uniprot id: U5MS10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1345695:CLSA RS19700
gene id: 1345695:CLSA_RS19700
uniprot id: U5MW91
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS20795
gene id: 1345695:CLSA_RS20795
uniprot id: U5MXK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Cell membrane
messages: Membrane
messages: O-acyltransferase that catalyzes D-alanylation of both teichoic acid and lipoteichoic acid (LTA). D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Catalyzes D-alanylation from DltC carrier protein.

1345695:CLSA RS02500
gene id: 1345695:CLSA_RS02500
uniprot id: U5MLS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1345695:CLSA RS08310
gene id: 1345695:CLSA_RS08310
uniprot id: U5MQ32
names: Similarity
messages: Belongs to the DtxR/MntR family.

1345695:CLSA RS01025
gene id: 1345695:CLSA_RS01025
uniprot id: U5MP86
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1345695:CLSA RS05195
gene id: 1345695:CLSA_RS05195
uniprot id: U5MMP7
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

1345695:CLSA RS12770
gene id: 1345695:CLSA_RS12770
uniprot id: U5MS40
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1345695:CLSA RS15685
gene id: 1345695:CLSA_RS15685
uniprot id: U5MUD2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1345695:CLSA RS20225
gene id: 1345695:CLSA_RS20225
uniprot id: U5MWI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS21860
gene id: 1345695:CLSA_RS21860
uniprot id: U5MY53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

1345695:CLSA RS08635
gene id: 1345695:CLSA_RS08635
uniprot id: U5MTI5
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS19025
gene id: 1345695:CLSA_RS19025
uniprot id: U5MWM8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1345695:CLSA RS18810
gene id: 1345695:CLSA_RS18810
uniprot id: U5MWI4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1345695:CLSA RS20580
gene id: 1345695:CLSA_RS20580
uniprot id: U5N0B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1345695:CLSA RS02085
gene id: 1345695:CLSA_RS02085
uniprot id: U5MLS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1345695:CLSA RS20395
gene id: 1345695:CLSA_RS20395
uniprot id: U5MX75
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1345695:CLSA RS06655
gene id: 1345695:CLSA_RS06655
uniprot id: U5MP45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1345695:CLSA RS07600
gene id: 1345695:CLSA_RS07600
uniprot id: U5MPP9
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

1345695:CLSA RS00710
gene id: 1345695:CLSA_RS00710
uniprot id: U5MKR5
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1345695:CLSA RS21575
gene id: 1345695:CLSA_RS21575
uniprot id: U5MY10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1345695:CLSA RS18595
gene id: 1345695:CLSA_RS18595
uniprot id: U5MWA2
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS10360
gene id: 1345695:CLSA_RS10360
uniprot id: U5MQN9
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1345695:CLSA RS13295
gene id: 1345695:CLSA_RS13295
uniprot id: U5MSZ9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1345695:CLSA RS03595
gene id: 1345695:CLSA_RS03595
uniprot id: U5MMC8
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1345695:CLSA RS06790
gene id: 1345695:CLSA_RS06790
uniprot id: U5MSL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1345695:CLSA RS02750
gene id: 1345695:CLSA_RS02750
uniprot id: U5MLA2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1345695:CLSA RS00840
gene id: 1345695:CLSA_RS00840
uniprot id: U5MNF4
names: Similarity
messages: Belongs to the CtsR family.

1345695:CLSA RS06435
gene id: 1345695:CLSA_RS06435
uniprot id: U5MRM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1345695:CLSA RS11705
gene id: 1345695:CLSA_RS11705
uniprot id: U5MS39
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1345695:CLSA RS07500
gene id: 1345695:CLSA_RS07500
uniprot id: U5MPN0
names: Similarity
messages: Belongs to the UPF0237 family.

1345695:CLSA RS03320
gene id: 1345695:CLSA_RS03320
uniprot id: U5MM64
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1345695:CLSA RS14745
gene id: 1345695:CLSA_RS14745
uniprot id: U5MTX2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1345695:CLSA RS06600
gene id: 1345695:CLSA_RS06600
uniprot id: U5MNH4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1345695:CLSA RS06825
gene id: 1345695:CLSA_RS06825
uniprot id: U5MNR1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1345695:CLSA RS01840
gene id: 1345695:CLSA_RS01840
uniprot id: U5MPU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS02235
gene id: 1345695:CLSA_RS02235
uniprot id: U5MPZ9
names: Similarity
messages: Belongs to the peptidase M13 family.

1345695:CLSA RS06345
gene id: 1345695:CLSA_RS06345
uniprot id: U5MP49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1345695:CLSA RS02625
gene id: 1345695:CLSA_RS02625
uniprot id: U5MM06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1345695:CLSA RS01610
gene id: 1345695:CLSA_RS01610
uniprot id: U5MLD2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1345695:CLSA RS01725
gene id: 1345695:CLSA_RS01725
uniprot id: U5MKV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

1345695:CLSA RS05355
gene id: 1345695:CLSA_RS05355
uniprot id: U5MRQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1345695:CLSA RS19950
gene id: 1345695:CLSA_RS19950
uniprot id: U5MWY3
names: Similarity
messages: Belongs to the EamA transporter family.

1345695:CLSA RS15790
gene id: 1345695:CLSA_RS15790
uniprot id: U5MXQ5
names: Similarity
messages: Belongs to the EamA transporter family.

1345695:CLSA RS07250
gene id: 1345695:CLSA_RS07250
uniprot id: U5MN47
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1345695:CLSA RS06715
gene id: 1345695:CLSA_RS06715
uniprot id: U5MSJ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1345695:CLSA RS11825
gene id: 1345695:CLSA_RS11825
uniprot id: U5MS65
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS19480
gene id: 1345695:CLSA_RS19480
uniprot id: U5MZS7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1345695:CLSA RS18610
gene id: 1345695:CLSA_RS18610
uniprot id: U5MYU5
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1345695:CLSA RS23730
gene id: 1345695:CLSA_RS23730
uniprot id: U5MPR6
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1345695:CLSA RS19090
gene id: 1345695:CLSA_RS19090
uniprot id: U5MZ65
names: Similarity
messages: Belongs to the bacterial flagellin family.

1345695:CLSA RS14575
gene id: 1345695:CLSA_RS14575
uniprot id: U5MWK0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1345695:CLSA RS18165
gene id: 1345695:CLSA_RS18165
uniprot id: U5MW15
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1345695:CLSA RS03455
gene id: 1345695:CLSA_RS03455
uniprot id: U5MPV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1345695:CLSA RS10220
gene id: 1345695:CLSA_RS10220
uniprot id: U5MTV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS05825
gene id: 1345695:CLSA_RS05825
uniprot id: U5MNU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1345695:CLSA RS02380
gene id: 1345695:CLSA_RS02380
uniprot id: U5MQ18
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

1345695:CLSA RS06050
gene id: 1345695:CLSA_RS06050
uniprot id: U5MN60
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1345695:CLSA RS05045
gene id: 1345695:CLSA_RS05045
uniprot id: U5MMM1
names: Similarity
messages: Belongs to the thioredoxin family.

1345695:CLSA RS06900
gene id: 1345695:CLSA_RS06900
uniprot id: U5MNS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1345695:CLSA RS04825
gene id: 1345695:CLSA_RS04825
uniprot id: U5MNB7
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1345695:CLSA RS01100
gene id: 1345695:CLSA_RS01100
uniprot id: U5ML62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1345695:CLSA RS06570
gene id: 1345695:CLSA_RS06570
uniprot id: U5MP93
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1345695:CLSA RS14970
gene id: 1345695:CLSA_RS14970
uniprot id: U5MXA2
names: Similarity
messages: Belongs to the peptidase S16 family.

1345695:CLSA RS12820
gene id: 1345695:CLSA_RS12820
uniprot id: U5MS49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS00030
gene id: 1345695:CLSA_RS00030
uniprot id: U5MJV8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1345695:CLSA RS16840
gene id: 1345695:CLSA_RS16840
uniprot id: U5MUN0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1345695:CLSA RS22095
gene id: 1345695:CLSA_RS22095
uniprot id: U5MUM9
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1345695:CLSA RS19865
gene id: 1345695:CLSA_RS19865
uniprot id: U5MX27
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS21780
gene id: 1345695:CLSA_RS21780
uniprot id: U5N134
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS00320
gene id: 1345695:CLSA_RS00320
uniprot id: U5MKS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1345695:CLSA RS04155
gene id: 1345695:CLSA_RS04155
uniprot id: U5MMQ0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1345695:CLSA RS15615
gene id: 1345695:CLSA_RS15615
uniprot id: U5MUL2
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS16310
gene id: 1345695:CLSA_RS16310
uniprot id: U5MN47
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1345695:CLSA RS20670
gene id: 1345695:CLSA_RS20670
uniprot id: U5N001
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1345695:CLSA RS19560
gene id: 1345695:CLSA_RS19560
uniprot id: U5MWX1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1345695:CLSA RS05985
gene id: 1345695:CLSA_RS05985
uniprot id: U5MNQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1345695:CLSA RS12205
gene id: 1345695:CLSA_RS12205
uniprot id: U5MV34
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type II sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

1345695:CLSA RS15775
gene id: 1345695:CLSA_RS15775
uniprot id: U5MTX9
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS15665
gene id: 1345695:CLSA_RS15665
uniprot id: U5MXP2
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS10675
gene id: 1345695:CLSA_RS10675
uniprot id: U5MUQ7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS19395
gene id: 1345695:CLSA_RS19395
uniprot id: U5MW51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1345695:CLSA RS02840
gene id: 1345695:CLSA_RS02840
uniprot id: U5MPI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS05975
gene id: 1345695:CLSA_RS05975
uniprot id: U5MNX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1345695:CLSA RS07445
gene id: 1345695:CLSA_RS07445
uniprot id: U5MP14
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1345695:CLSA RS04160
gene id: 1345695:CLSA_RS04160
uniprot id: U5MQC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

1345695:CLSA RS01755
gene id: 1345695:CLSA_RS01755
uniprot id: U5MLG2
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1345695:CLSA RS10870
gene id: 1345695:CLSA_RS10870
uniprot id: U5MRS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1345695:CLSA RS11240
gene id: 1345695:CLSA_RS11240
uniprot id: U5MR62
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1345695:CLSA RS07085
gene id: 1345695:CLSA_RS07085
uniprot id: U5MPF7
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1345695:CLSA RS10375
gene id: 1345695:CLSA_RS10375
uniprot id: U5MUK4
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS00895
gene id: 1345695:CLSA_RS00895
uniprot id: U5MP62
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1345695:CLSA RS07160
gene id: 1345695:CLSA_RS07160
uniprot id: U5MNW6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1345695:CLSA RS12700
gene id: 1345695:CLSA_RS12700
uniprot id: U5MSL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

1345695:CLSA RS12170
gene id: 1345695:CLSA_RS12170
uniprot id: U5MVP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

1345695:CLSA RS01000
gene id: 1345695:CLSA_RS01000
uniprot id: U5MP80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1345695:CLSA RS07585
gene id: 1345695:CLSA_RS07585
uniprot id: U5MPW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1345695:CLSA RS20240
gene id: 1345695:CLSA_RS20240
uniprot id: U5N055
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1345695:CLSA RS20640
gene id: 1345695:CLSA_RS20640
uniprot id: U5MXC7
names: Similarity
messages: Belongs to the pyruvate kinase family.

1345695:CLSA RS07895
gene id: 1345695:CLSA_RS07895
uniprot id: U5MSI2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS01575
gene id: 1345695:CLSA_RS01575
uniprot id: U5MLC9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1345695:CLSA RS15180
gene id: 1345695:CLSA_RS15180
uniprot id: U5MU62
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS18840
gene id: 1345695:CLSA_RS18840
uniprot id: U5MWD4
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1345695:CLSA RS06630
gene id: 1345695:CLSA_RS06630
uniprot id: U5MP39
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

1345695:CLSA RS06430
gene id: 1345695:CLSA_RS06430
uniprot id: U5MNZ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1345695:CLSA RS08750
gene id: 1345695:CLSA_RS08750
uniprot id: U5MSZ6
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Homodimer.

1345695:CLSA RS15110
gene id: 1345695:CLSA_RS15110
uniprot id: U5MWV4
names: Similarity
messages: Belongs to the UPF0735 family.

1345695:CLSA RS13860
gene id: 1345695:CLSA_RS13860
uniprot id: U5MW29
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1345695:CLSA RS19200
gene id: 1345695:CLSA_RS19200
uniprot id: U5MWQ6
names: Similarity
messages: Belongs to the RecJ family.

1345695:CLSA RS01210
gene id: 1345695:CLSA_RS01210
uniprot id: U5MKF5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1345695:CLSA RS15015
gene id: 1345695:CLSA_RS15015
uniprot id: U5MWT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1345695:CLSA RS04955
gene id: 1345695:CLSA_RS04955
uniprot id: U5MN73
names: Similarity
messages: Belongs to the MotB family.

1345695:CLSA RS10990
gene id: 1345695:CLSA_RS10990
uniprot id: U5MUW3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1345695:CLSA RS08650
gene id: 1345695:CLSA_RS08650
uniprot id: U5MQA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1345695:CLSA RS03480
gene id: 1345695:CLSA_RS03480
uniprot id: U5MQL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1345695:CLSA RS05035
gene id: 1345695:CLSA_RS05035
uniprot id: U5MRI9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1345695:CLSA RS00890
gene id: 1345695:CLSA_RS00890
uniprot id: U5MNG4
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1345695:CLSA RS13020
gene id: 1345695:CLSA_RS13020
uniprot id: U5MVK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1345695:CLSA RS06670
gene id: 1345695:CLSA_RS06670
uniprot id: U5MPD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1345695:CLSA RS19470
gene id: 1345695:CLSA_RS19470
uniprot id: U5MW62
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1345695:CLSA RS04405
gene id: 1345695:CLSA_RS04405
uniprot id: U5MMY0
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1345695:CLSA RS03085
gene id: 1345695:CLSA_RS03085
uniprot id: U5MM88
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS12000
gene id: 1345695:CLSA_RS12000
uniprot id: U5MQP3
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1345695:CLSA RS18930
gene id: 1345695:CLSA_RS18930
uniprot id: U5MWL0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1345695:CLSA RS00715
gene id: 1345695:CLSA_RS00715
uniprot id: U5MND8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1345695:CLSA RS19185
gene id: 1345695:CLSA_RS19185
uniprot id: U5MWJ2
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1345695:CLSA RS09990
gene id: 1345695:CLSA_RS09990
uniprot id: U5MUD5
names: Subcellular Location Annotation
messages: Cytoplasm

1345695:CLSA RS02915
gene id: 1345695:CLSA_RS02915
uniprot id: U5MLY8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1345695:CLSA RS00515
gene id: 1345695:CLSA_RS00515
uniprot id: U5MNA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1345695:CLSA RS05375
gene id: 1345695:CLSA_RS05375
uniprot id: U5MR10
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1345695:CLSA RS21255
gene id: 1345695:CLSA_RS21255
uniprot id: U5MX36
names: Similarity
messages: Belongs to the CFA/CMAS family.

1345695:CLSA RS14820
gene id: 1345695:CLSA_RS14820
uniprot id: U5MTY5
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1345695:CLSA RS18255
gene id: 1345695:CLSA_RS18255
uniprot id: U5MZ13
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

1345695:CLSA RS03735
gene id: 1345695:CLSA_RS03735
uniprot id: U5MMM3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

1345695:CLSA RS03430
gene id: 1345695:CLSA_RS03430
uniprot id: U5MPU8
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1345695:CLSA RS06155
gene id: 1345695:CLSA_RS06155
uniprot id: U5MNU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS03150
gene id: 1345695:CLSA_RS03150
uniprot id: U5MM34
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1345695:CLSA RS01820
gene id: 1345695:CLSA_RS01820
uniprot id: U5MLP7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS16365
gene id: 1345695:CLSA_RS16365
uniprot id: U5MY52
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1345695:CLSA RS21355
gene id: 1345695:CLSA_RS21355
uniprot id: U5MXU2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS06910
gene id: 1345695:CLSA_RS06910
uniprot id: U5MS11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1345695:CLSA RS15580
gene id: 1345695:CLSA_RS15580
uniprot id: U5MX59
names: Similarity
messages: Belongs to the CobH/CbiC family.

1345695:CLSA RS20905
gene id: 1345695:CLSA_RS20905
uniprot id: U5MWX4
names: Similarity
messages: Belongs to the CinA family.

1345695:CLSA RS19505
gene id: 1345695:CLSA_RS19505
uniprot id: U5MZT2
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1345695:CLSA RS18275
gene id: 1345695:CLSA_RS18275
uniprot id: U5MYM9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

1345695:CLSA RS07295
gene id: 1345695:CLSA_RS07295
uniprot id: U5MNZ0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS07095
gene id: 1345695:CLSA_RS07095
uniprot id: U5MSQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Cell membrane

1345695:CLSA RS13635
gene id: 1345695:CLSA_RS13635
uniprot id: U5MVX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS05560
gene id: 1345695:CLSA_RS05560
uniprot id: U5MR40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1345695:CLSA RS00220
gene id: 1345695:CLSA_RS00220
uniprot id: U5MNW0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS21510
gene id: 1345695:CLSA_RS21510
uniprot id: U5MXC4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1345695:CLSA RS02435
gene id: 1345695:CLSA_RS02435
uniprot id: U5MLX6
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1345695:CLSA RS02725
gene id: 1345695:CLSA_RS02725
uniprot id: U5ML98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1345695:CLSA RS20515
gene id: 1345695:CLSA_RS20515
uniprot id: U5MWP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS19195
gene id: 1345695:CLSA_RS19195
uniprot id: U5MZM5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS03040
gene id: 1345695:CLSA_RS03040
uniprot id: U5MM78
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS01145
gene id: 1345695:CLSA_RS01145
uniprot id: U5MPB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1345695:CLSA RS20940
gene id: 1345695:CLSA_RS20940
uniprot id: U5N054
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS06490
gene id: 1345695:CLSA_RS06490
uniprot id: U5MSA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1345695:CLSA RS00190
gene id: 1345695:CLSA_RS00190
uniprot id: U5MN44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1345695:CLSA RS12635
gene id: 1345695:CLSA_RS12635
uniprot id: U5MVX0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1345695:CLSA RS08660
gene id: 1345695:CLSA_RS08660
uniprot id: U5MTI9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1345695:CLSA RS19010
gene id: 1345695:CLSA_RS19010
uniprot id: U5MWG1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1345695:CLSA RS04800
gene id: 1345695:CLSA_RS04800
uniprot id: U5MNB3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1345695:CLSA RS00690
gene id: 1345695:CLSA_RS00690
uniprot id: U5MND1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1345695:CLSA RS12775
gene id: 1345695:CLSA_RS12775
uniprot id: U5MSN4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1345695:CLSA RS13845
gene id: 1345695:CLSA_RS13845
uniprot id: U5MTH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1345695:CLSA RS10645
gene id: 1345695:CLSA_RS10645
uniprot id: U5MU34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS01865
gene id: 1345695:CLSA_RS01865
uniprot id: U5MPV3
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS08855
gene id: 1345695:CLSA_RS08855
uniprot id: U5MTM8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1345695:CLSA RS20850
gene id: 1345695:CLSA_RS20850
uniprot id: U5MXI0
names: Similarity
messages: Belongs to the peptidase C40 family.

1345695:CLSA RS04200
gene id: 1345695:CLSA_RS04200
uniprot id: U5MM72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS13490
gene id: 1345695:CLSA_RS13490
uniprot id: U5MT43
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1345695:CLSA RS00960
gene id: 1345695:CLSA_RS00960
uniprot id: U5MKA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1345695:CLSA RS08460
gene id: 1345695:CLSA_RS08460
uniprot id: U5MQ62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1345695:CLSA RS15940
gene id: 1345695:CLSA_RS15940
uniprot id: U5MXS9
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS21785
gene id: 1345695:CLSA_RS21785
uniprot id: U5MY41
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1345695:CLSA RS15540
gene id: 1345695:CLSA_RS15540
uniprot id: U5MUJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1345695:CLSA RS14790
gene id: 1345695:CLSA_RS14790
uniprot id: U5MTE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

1345695:CLSA RS18395
gene id: 1345695:CLSA_RS18395
uniprot id: U5MVF4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1345695:CLSA RS14915
gene id: 1345695:CLSA_RS14915
uniprot id: U5MU05
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1345695:CLSA RS01350
gene id: 1345695:CLSA_RS01350
uniprot id: U5MNQ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1345695:CLSA RS17715
gene id: 1345695:CLSA_RS17715
uniprot id: U5MYC8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1345695:CLSA RS06850
gene id: 1345695:CLSA_RS06850
uniprot id: U5MNR6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1345695:CLSA RS03010
gene id: 1345695:CLSA_RS03010
uniprot id: U5MM75
names: Similarity
messages: Belongs to the transpeptidase family.

1345695:CLSA RS03740
gene id: 1345695:CLSA_RS03740
uniprot id: U5MLU4
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1345695:CLSA RS04680
gene id: 1345695:CLSA_RS04680
uniprot id: U5MN21
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS20785
gene id: 1345695:CLSA_RS20785
uniprot id: U5N025
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS00855
gene id: 1345695:CLSA_RS00855
uniprot id: U5MK82
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1345695:CLSA RS20005
gene id: 1345695:CLSA_RS20005
uniprot id: U5MX54
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

1345695:CLSA RS06860
gene id: 1345695:CLSA_RS06860
uniprot id: U5MS03
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1345695:CLSA RS15095
gene id: 1345695:CLSA_RS15095
uniprot id: U5MUB0
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS12760
gene id: 1345695:CLSA_RS12760
uniprot id: U5MVZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1345695:CLSA RS08315
gene id: 1345695:CLSA_RS08315
uniprot id: U5MTB9
names: Similarity
messages: Belongs to the UPF0751 family.

1345695:CLSA RS01110
gene id: 1345695:CLSA_RS01110
uniprot id: U5MKY8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

1345695:CLSA RS20675
gene id: 1345695:CLSA_RS20675
uniprot id: U5N0D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1345695:CLSA RS12350
gene id: 1345695:CLSA_RS12350
uniprot id: U5MV62
names: Similarity
messages: Belongs to the EamA transporter family.

1345695:CLSA RS11005
gene id: 1345695:CLSA_RS11005
uniprot id: U5MRL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1345695:CLSA RS18920
gene id: 1345695:CLSA_RS18920
uniprot id: U5MZ43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1345695:CLSA RS02160
gene id: 1345695:CLSA_RS02160
uniprot id: U5MLL3
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1345695:CLSA RS18440
gene id: 1345695:CLSA_RS18440
uniprot id: U5MVG7
names: Similarity
messages: Belongs to the DtxR/MntR family.

1345695:CLSA RS04370
gene id: 1345695:CLSA_RS04370
uniprot id: U5MR81
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1345695:CLSA RS19410
gene id: 1345695:CLSA_RS19410
uniprot id: U5MZR4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1345695:CLSA RS18745
gene id: 1345695:CLSA_RS18745
uniprot id: U5MVN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1345695:CLSA RS02780
gene id: 1345695:CLSA_RS02780
uniprot id: U5MLW3
names: Similarity
messages: Belongs to the hemerythrin family.

1345695:CLSA RS15045
gene id: 1345695:CLSA_RS15045
uniprot id: U5MXB8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1345695:CLSA RS24055
gene id: 1345695:CLSA_RS24055
uniprot id: U5MTP2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1345695:CLSA RS04940
gene id: 1345695:CLSA_RS04940
uniprot id: U5MRH7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1345695:CLSA RS19850
gene id: 1345695:CLSA_RS19850
uniprot id: U5MWW1
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1345695:CLSA RS06235
gene id: 1345695:CLSA_RS06235
uniprot id: U5MRI1
names: Similarity
messages: Belongs to the CvfB family.

1345695:CLSA RS09730
gene id: 1345695:CLSA_RS09730
uniprot id: U5MQD5
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS18645
gene id: 1345695:CLSA_RS18645
uniprot id: U5MWB1
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1345695:CLSA RS20700
gene id: 1345695:CLSA_RS20700
uniprot id: U5MXI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1345695:CLSA RS21365
gene id: 1345695:CLSA_RS21365
uniprot id: U5MXX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AgrB family.
messages: Cell membrane
messages: May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor.

1345695:CLSA RS01200
gene id: 1345695:CLSA_RS01200
uniprot id: U5MPB9
names: Similarity
messages: Belongs to the class-I fumarase family.

1345695:CLSA RS11685
gene id: 1345695:CLSA_RS11685
uniprot id: U5MUU7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1345695:CLSA RS07290
gene id: 1345695:CLSA_RS07290
uniprot id: U5MPR1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1345695:CLSA RS09175
gene id: 1345695:CLSA_RS09175
uniprot id: U5MQL9
names: Similarity
messages: Belongs to the asparagine synthetase family.

1345695:CLSA RS10960
gene id: 1345695:CLSA_RS10960
uniprot id: U5MR08
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1345695:CLSA RS20730
gene id: 1345695:CLSA_RS20730
uniprot id: U5MWT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1345695:CLSA RS09190
gene id: 1345695:CLSA_RS09190
uniprot id: U5MQ30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1345695:CLSA RS06885
gene id: 1345695:CLSA_RS06885
uniprot id: U5MS07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1345695:CLSA RS05705
gene id: 1345695:CLSA_RS05705
uniprot id: U5MMY7
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1345695:CLSA RS18700
gene id: 1345695:CLSA_RS18700
uniprot id: U5MW68
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS05530
gene id: 1345695:CLSA_RS05530
uniprot id: U5MNH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1345695:CLSA RS06440
gene id: 1345695:CLSA_RS06440
uniprot id: U5MS96
names: Function
names: Similarity
names: Subunit
messages: Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
messages: Belongs to the HutP family.
messages: Homohexamer.

1345695:CLSA RS09660
gene id: 1345695:CLSA_RS09660
uniprot id: U5MQC3
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1345695:CLSA RS06625
gene id: 1345695:CLSA_RS06625
uniprot id: U5MNH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1345695:CLSA RS15440
gene id: 1345695:CLSA_RS15440
uniprot id: U5MX30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1345695:CLSA RS16755
gene id: 1345695:CLSA_RS16755
uniprot id: U5MVA8
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS12930
gene id: 1345695:CLSA_RS12930
uniprot id: U5MSZ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS06400
gene id: 1345695:CLSA_RS06400
uniprot id: U5MNC7
names: Similarity
messages: Belongs to the fabD family.

1345695:CLSA RS15445
gene id: 1345695:CLSA_RS15445
uniprot id: U5MXK3
names: Similarity
messages: Belongs to the KdgT transporter family.

1345695:CLSA RS15285
gene id: 1345695:CLSA_RS15285
uniprot id: U5MTN1
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

1345695:CLSA RS21170
gene id: 1345695:CLSA_RS21170
uniprot id: U5N081
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS06270
gene id: 1345695:CLSA_RS06270
uniprot id: U5MP35
names: Similarity
messages: Belongs to the thioredoxin family.

1345695:CLSA RS02900
gene id: 1345695:CLSA_RS02900
uniprot id: U5MQA6
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

1345695:CLSA RS13775
gene id: 1345695:CLSA_RS13775
uniprot id: U5MSN8
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS00005
gene id: 1345695:CLSA_RS00005
uniprot id: U5MJV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1345695:CLSA RS10710
gene id: 1345695:CLSA_RS10710
uniprot id: U5MQV4
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS18975
gene id: 1345695:CLSA_RS18975
uniprot id: U5MWL9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1345695:CLSA RS13905
gene id: 1345695:CLSA_RS13905
uniprot id: U5MW39
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1345695:CLSA RS20590
gene id: 1345695:CLSA_RS20590
uniprot id: U5MWQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1345695:CLSA RS10705
gene id: 1345695:CLSA_RS10705
uniprot id: U5MRP0
names: Subcellular Location Annotation
messages: Cytoplasm

1345695:CLSA RS00980
gene id: 1345695:CLSA_RS00980
uniprot id: U5ML39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1345695:CLSA RS09795
gene id: 1345695:CLSA_RS09795
uniprot id: U5MTM5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS13175
gene id: 1345695:CLSA_RS13175
uniprot id: U5MW74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1345695:CLSA RS06845
gene id: 1345695:CLSA_RS06845
uniprot id: U5MPJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1345695:CLSA RS13840
gene id: 1345695:CLSA_RS13840
uniprot id: U5MWJ8
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1345695:CLSA RS10280
gene id: 1345695:CLSA_RS10280
uniprot id: U5MUI4
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1345695:CLSA RS03335
gene id: 1345695:CLSA_RS03335
uniprot id: U5MLK5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS02475
gene id: 1345695:CLSA_RS02475
uniprot id: U5MPD1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1345695:CLSA RS06765
gene id: 1345695:CLSA_RS06765
uniprot id: U5MSK7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS20000
gene id: 1345695:CLSA_RS20000
uniprot id: U5MZL4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1345695:CLSA RS07215
gene id: 1345695:CLSA_RS07215
uniprot id: U5MPI0
names: Function
names: Similarity
names: Subunit
messages: In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.
messages: Monomer.
messages: Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine.

1345695:CLSA RS23560
gene id: 1345695:CLSA_RS23560
uniprot id: U5MPZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS03680
gene id: 1345695:CLSA_RS03680
uniprot id: U5MQQ4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1345695:CLSA RS01885
gene id: 1345695:CLSA_RS01885
uniprot id: U5MP60
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1345695:CLSA RS16210
gene id: 1345695:CLSA_RS16210
uniprot id: U5MU70
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

1345695:CLSA RS20320
gene id: 1345695:CLSA_RS20320
uniprot id: U5MWK1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1345695:CLSA RS09890
gene id: 1345695:CLSA_RS09890
uniprot id: U5MTP0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS21220
gene id: 1345695:CLSA_RS21220
uniprot id: U5N0N6
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1345695:CLSA RS04860
gene id: 1345695:CLSA_RS04860
uniprot id: U5MQR9
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS06115
gene id: 1345695:CLSA_RS06115
uniprot id: U5MS33
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

1345695:CLSA RS15700
gene id: 1345695:CLSA_RS15700
uniprot id: U5MTW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1345695:CLSA RS09540
gene id: 1345695:CLSA_RS09540
uniprot id: U5MQA5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS07355
gene id: 1345695:CLSA_RS07355
uniprot id: U5MS86
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1345695:CLSA RS02690
gene id: 1345695:CLSA_RS02690
uniprot id: U5MQ66
names: Similarity
messages: Belongs to the EamA transporter family.

1345695:CLSA RS06500
gene id: 1345695:CLSA_RS06500
uniprot id: U5MNF1
names: Similarity
messages: Belongs to the Fur family.

1345695:CLSA RS02705
gene id: 1345695:CLSA_RS02705
uniprot id: U5MLV1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1345695:CLSA RS11015
gene id: 1345695:CLSA_RS11015
uniprot id: U5MUW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS02190
gene id: 1345695:CLSA_RS02190
uniprot id: U5MN47
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1345695:CLSA RS15810
gene id: 1345695:CLSA_RS15810
uniprot id: U5MXA3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1345695:CLSA RS08565
gene id: 1345695:CLSA_RS08565
uniprot id: U5MTH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS15390
gene id: 1345695:CLSA_RS15390
uniprot id: U5MTQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0397 family.
messages: Cell membrane

1345695:CLSA RS14985
gene id: 1345695:CLSA_RS14985
uniprot id: U5MU19
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1345695:CLSA RS11495
gene id: 1345695:CLSA_RS11495
uniprot id: U5MV64
names: Similarity
messages: Belongs to the UPF0111 family.

1345695:CLSA RS05655
gene id: 1345695:CLSA_RS05655
uniprot id: U5MNJ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1345695:CLSA RS13800
gene id: 1345695:CLSA_RS13800
uniprot id: U5MSR3
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1345695:CLSA RS00795
gene id: 1345695:CLSA_RS00795
uniprot id: U5MP47
names: Similarity
messages: Belongs to the peptidase M20A family.

1345695:CLSA RS19755
gene id: 1345695:CLSA_RS19755
uniprot id: U5MWU1
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

1345695:CLSA RS06255
gene id: 1345695:CLSA_RS06255
uniprot id: U5MNW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS04840
gene id: 1345695:CLSA_RS04840
uniprot id: U5MQR6
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1345695:CLSA RS19450
gene id: 1345695:CLSA_RS19450
uniprot id: U5MWP1
names: Similarity
messages: Belongs to the sigma-54 factor family.

1345695:CLSA RS10325
gene id: 1345695:CLSA_RS10325
uniprot id: U5MTW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1345695:CLSA RS18785
gene id: 1345695:CLSA_RS18785
uniprot id: U5MWG0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1345695:CLSA RS20810
gene id: 1345695:CLSA_RS20810
uniprot id: U5N0H0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1345695:CLSA RS04980
gene id: 1345695:CLSA_RS04980
uniprot id: U5MN77
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1345695:CLSA RS03485
gene id: 1345695:CLSA_RS03485
uniprot id: U5MMH2
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1345695:CLSA RS07625
gene id: 1345695:CLSA_RS07625
uniprot id: U5MPQ4
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1345695:CLSA RS02455
gene id: 1345695:CLSA_RS02455
uniprot id: U5MQ29
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1345695:CLSA RS17230
gene id: 1345695:CLSA_RS17230
uniprot id: U5MVC9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1345695:CLSA RS20325
gene id: 1345695:CLSA_RS20325
uniprot id: U5MX62
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1345695:CLSA RS21660
gene id: 1345695:CLSA_RS21660
uniprot id: U5N113
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS04575
gene id: 1345695:CLSA_RS04575
uniprot id: U5MN72
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1345695:CLSA RS02510
gene id: 1345695:CLSA_RS02510
uniprot id: U5MQ38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1345695:CLSA RS19145
gene id: 1345695:CLSA_RS19145
uniprot id: U5MZL7
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1345695:CLSA RS21875
gene id: 1345695:CLSA_RS21875
uniprot id: U5N0N4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1345695:CLSA RS12145
gene id: 1345695:CLSA_RS12145
uniprot id: U5MVN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1345695:CLSA RS07690
gene id: 1345695:CLSA_RS07690
uniprot id: U5MPY5
names: Similarity
messages: Belongs to the manganese catalase family.

1345695:CLSA RS08910
gene id: 1345695:CLSA_RS08910
uniprot id: U5MPT7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

1345695:CLSA RS19635
gene id: 1345695:CLSA_RS19635
uniprot id: U5MWY4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS21165
gene id: 1345695:CLSA_RS21165
uniprot id: U5MXM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS01090
gene id: 1345695:CLSA_RS01090
uniprot id: U5MNK5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1345695:CLSA RS20875
gene id: 1345695:CLSA_RS20875
uniprot id: U5MWW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1345695:CLSA RS06550
gene id: 1345695:CLSA_RS06550
uniprot id: U5MNG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.

1345695:CLSA RS05065
gene id: 1345695:CLSA_RS05065
uniprot id: U5MNG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1345695:CLSA RS18095
gene id: 1345695:CLSA_RS18095
uniprot id: U5MVZ9
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1345695:CLSA RS07880
gene id: 1345695:CLSA_RS07880
uniprot id: U5MQ17
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1345695:CLSA RS05885
gene id: 1345695:CLSA_RS05885
uniprot id: U5MNN5
names: Similarity
messages: Belongs to the peptidase S11 family.

1345695:CLSA RS12920
gene id: 1345695:CLSA_RS12920
uniprot id: U5MVI1
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1345695:CLSA RS04150
gene id: 1345695:CLSA_RS04150
uniprot id: U5MM30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
messages: Cytoplasm

1345695:CLSA RS13510
gene id: 1345695:CLSA_RS13510
uniprot id: U5MSI1
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS03670
gene id: 1345695:CLSA_RS03670
uniprot id: U5MME5
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS10455
gene id: 1345695:CLSA_RS10455
uniprot id: U5MTZ2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1345695:CLSA RS16710
gene id: 1345695:CLSA_RS16710
uniprot id: U5MUL0
names: Similarity
messages: Belongs to the PrpF family.

1345695:CLSA RS21320
gene id: 1345695:CLSA_RS21320
uniprot id: U5N0U4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1345695:CLSA RS17650
gene id: 1345695:CLSA_RS17650
uniprot id: U5MVR9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1345695:CLSA RS02740
gene id: 1345695:CLSA_RS02740
uniprot id: U5MQ77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1345695:CLSA RS10470
gene id: 1345695:CLSA_RS10470
uniprot id: U5MQR1
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS03230
gene id: 1345695:CLSA_RS03230
uniprot id: U5MPQ0
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

1345695:CLSA RS05735
gene id: 1345695:CLSA_RS05735
uniprot id: U5MR77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1345695:CLSA RS15435
gene id: 1345695:CLSA_RS15435
uniprot id: U5MUB3
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS02450
gene id: 1345695:CLSA_RS02450
uniprot id: U5MPC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1345695:CLSA RS12240
gene id: 1345695:CLSA_RS12240
uniprot id: U5MSM1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1345695:CLSA RS03885
gene id: 1345695:CLSA_RS03885
uniprot id: U5MLX4
names: Similarity
messages: Belongs to the 'phage' integrase family.

1345695:CLSA RS06455
gene id: 1345695:CLSA_RS06455
uniprot id: U5MP01
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

1345695:CLSA RS02735
gene id: 1345695:CLSA_RS02735
uniprot id: U5MPG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1345695:CLSA RS16235
gene id: 1345695:CLSA_RS16235
uniprot id: U5MU75
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1345695:CLSA RS17035
gene id: 1345695:CLSA_RS17035
uniprot id: U5MY09
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1345695:CLSA RS15185
gene id: 1345695:CLSA_RS15185
uniprot id: U5MWX0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1345695:CLSA RS19050
gene id: 1345695:CLSA_RS19050
uniprot id: U5MWN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1345695:CLSA RS20110
gene id: 1345695:CLSA_RS20110
uniprot id: U5MZP0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1345695:CLSA RS16000
gene id: 1345695:CLSA_RS16000
uniprot id: U5MUS9
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1345695:CLSA RS13955
gene id: 1345695:CLSA_RS13955
uniprot id: U5MTD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

1345695:CLSA RS02495
gene id: 1345695:CLSA_RS02495
uniprot id: U5ML65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1345695:CLSA RS09205
gene id: 1345695:CLSA_RS09205
uniprot id: U5MTZ1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1345695:CLSA RS00275
gene id: 1345695:CLSA_RS00275
uniprot id: U5MJZ3
names: Similarity
messages: Belongs to the ComB family.

1345695:CLSA RS20625
gene id: 1345695:CLSA_RS20625
uniprot id: U5N0D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1345695:CLSA RS07150
gene id: 1345695:CLSA_RS07150
uniprot id: U5MSR1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1345695:CLSA RS01290
gene id: 1345695:CLSA_RS01290
uniprot id: U5ML25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1345695:CLSA RS14920
gene id: 1345695:CLSA_RS14920
uniprot id: U5MWR4
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1345695:CLSA RS18880
gene id: 1345695:CLSA_RS18880
uniprot id: U5MWJ9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1345695:CLSA RS18240
gene id: 1345695:CLSA_RS18240
uniprot id: U5MW32
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1345695:CLSA RS04835
gene id: 1345695:CLSA_RS04835
uniprot id: U5MN54
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1345695:CLSA RS07660
gene id: 1345695:CLSA_RS07660
uniprot id: U5MSZ7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1345695:CLSA RS06695
gene id: 1345695:CLSA_RS06695
uniprot id: U5MPG2
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1345695:CLSA RS15210
gene id: 1345695:CLSA_RS15210
uniprot id: U5MWX6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1345695:CLSA RS13450
gene id: 1345695:CLSA_RS13450
uniprot id: U5MWB8
names: Similarity
messages: Belongs to the peptidase M16 family.

1345695:CLSA RS05390
gene id: 1345695:CLSA_RS05390
uniprot id: U5MMT2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1345695:CLSA RS06800
gene id: 1345695:CLSA_RS06800
uniprot id: U5MNQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1345695:CLSA RS08555
gene id: 1345695:CLSA_RS08555
uniprot id: U5MQ83
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS13120
gene id: 1345695:CLSA_RS13120
uniprot id: U5MVM0
names: Subcellular Location Annotation
messages: Cytoplasm

1345695:CLSA RS16010
gene id: 1345695:CLSA_RS16010
uniprot id: U5MUM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS19945
gene id: 1345695:CLSA_RS19945
uniprot id: U5MWD3
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS01155
gene id: 1345695:CLSA_RS01155
uniprot id: U5MKE5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1345695:CLSA RS22085
gene id: 1345695:CLSA_RS22085
uniprot id: U5MUD6
names: Similarity
messages: Belongs to the peptidase C40 family.

1345695:CLSA RS18010
gene id: 1345695:CLSA_RS18010
uniprot id: U5MVY6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1345695:CLSA RS14270
gene id: 1345695:CLSA_RS14270
uniprot id: U5MTN6
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

1345695:CLSA RS19085
gene id: 1345695:CLSA_RS19085
uniprot id: U5MWH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

1345695:CLSA RS00900
gene id: 1345695:CLSA_RS00900
uniprot id: U5ML24
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1345695:CLSA RS02530
gene id: 1345695:CLSA_RS02530
uniprot id: U5MPE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS07835
gene id: 1345695:CLSA_RS07835
uniprot id: U5MP81
names: Similarity
messages: Belongs to the polypeptide deformylase family.

1345695:CLSA RS16815
gene id: 1345695:CLSA_RS16815
uniprot id: U5MQP3
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1345695:CLSA RS00850
gene id: 1345695:CLSA_RS00850
uniprot id: U5ML16
names: Caution
names: Function
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS22230
gene id: 1345695:CLSA_RS22230
uniprot id: U5MVD0
names: Similarity
messages: Belongs to the UPF0167 family.

1345695:CLSA RS03440
gene id: 1345695:CLSA_RS03440
uniprot id: U5MMG3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1345695:CLSA RS04715
gene id: 1345695:CLSA_RS04715
uniprot id: U5MRD8
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS00035
gene id: 1345695:CLSA_RS00035
uniprot id: U5MKF6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1345695:CLSA RS13335
gene id: 1345695:CLSA_RS13335
uniprot id: U5MT71
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1345695:CLSA RS12440
gene id: 1345695:CLSA_RS12440
uniprot id: U5MSG8
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1345695:CLSA RS13145
gene id: 1345695:CLSA_RS13145
uniprot id: U5MVM6
names: Similarity
messages: Belongs to the UPF0749 family.

1345695:CLSA RS15480
gene id: 1345695:CLSA_RS15480
uniprot id: U5MX40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Transport of potassium into the cell.

1345695:CLSA RS06480
gene id: 1345695:CLSA_RS06480
uniprot id: U5MP05
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1345695:CLSA RS17475
gene id: 1345695:CLSA_RS17475
uniprot id: U5MVH8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS00595
gene id: 1345695:CLSA_RS00595
uniprot id: U5MP25
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1345695:CLSA RS15570
gene id: 1345695:CLSA_RS15570
uniprot id: U5MTU1
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

1345695:CLSA RS02470
gene id: 1345695:CLSA_RS02470
uniprot id: U5MLR4
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1345695:CLSA RS12230
gene id: 1345695:CLSA_RS12230
uniprot id: U5MV39
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

1345695:CLSA RS01060
gene id: 1345695:CLSA_RS01060
uniprot id: U5MKX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1345695:CLSA RS13430
gene id: 1345695:CLSA_RS13430
uniprot id: U5MT90
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1345695:CLSA RS22135
gene id: 1345695:CLSA_RS22135
uniprot id: U5MTB2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1345695:CLSA RS00285
gene id: 1345695:CLSA_RS00285
uniprot id: U5MN67
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS11935
gene id: 1345695:CLSA_RS11935
uniprot id: U5MSG7
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

1345695:CLSA RS04070
gene id: 1345695:CLSA_RS04070
uniprot id: U5MQY3
names: Subcellular Location Annotation
messages: Secreted

1345695:CLSA RS12215
gene id: 1345695:CLSA_RS12215
uniprot id: U5MSL8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1345695:CLSA RS15360
gene id: 1345695:CLSA_RS15360
uniprot id: U5MTP7
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1345695:CLSA RS03460
gene id: 1345695:CLSA_RS03460
uniprot id: U5MQK9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS20765
gene id: 1345695:CLSA_RS20765
uniprot id: U5N0F8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS16340
gene id: 1345695:CLSA_RS16340
uniprot id: U5MY30
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1345695:CLSA RS07285
gene id: 1345695:CLSA_RS07285
uniprot id: U5MS74
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1345695:CLSA RS15770
gene id: 1345695:CLSA_RS15770
uniprot id: U5MUN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

1345695:CLSA RS05935
gene id: 1345695:CLSA_RS05935
uniprot id: U5MNP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS07400
gene id: 1345695:CLSA_RS07400
uniprot id: U5MPL4
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1345695:CLSA RS08110
gene id: 1345695:CLSA_RS08110
uniprot id: U5MSM6
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS14760
gene id: 1345695:CLSA_RS14760
uniprot id: U5MU40
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

1345695:CLSA RS12015
gene id: 1345695:CLSA_RS12015
uniprot id: U5MSH9
names: Similarity
messages: Belongs to the asparagine synthetase family.

1345695:CLSA RS12030
gene id: 1345695:CLSA_RS12030
uniprot id: U5MVL3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1345695:CLSA RS01745
gene id: 1345695:CLSA_RS01745
uniprot id: U5MLN4
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1345695:CLSA RS00940
gene id: 1345695:CLSA_RS00940
uniprot id: U5MKV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1345695:CLSA RS02515
gene id: 1345695:CLSA_RS02515
uniprot id: U5MLZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1345695:CLSA RS03000
gene id: 1345695:CLSA_RS03000
uniprot id: U5MPL1
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1345695:CLSA RS05940
gene id: 1345695:CLSA_RS05940
uniprot id: U5MRB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

1345695:CLSA RS00120
gene id: 1345695:CLSA_RS00120
uniprot id: U5MKP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

1345695:CLSA RS16810
gene id: 1345695:CLSA_RS16810
uniprot id: U5MVB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1345695:CLSA RS15760
gene id: 1345695:CLSA_RS15760
uniprot id: U5MX92
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS06420
gene id: 1345695:CLSA_RS06420
uniprot id: U5MP63
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1345695:CLSA RS03265
gene id: 1345695:CLSA_RS03265
uniprot id: U5MLJ0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1345695:CLSA RS19460
gene id: 1345695:CLSA_RS19460
uniprot id: U5MZS2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS09765
gene id: 1345695:CLSA_RS09765
uniprot id: U5MTM0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1345695:CLSA RS19760
gene id: 1345695:CLSA_RS19760
uniprot id: U5MZG5
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

1345695:CLSA RS11565
gene id: 1345695:CLSA_RS11565
uniprot id: U5MVA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspH family.
messages: Spore core

1345695:CLSA RS08715
gene id: 1345695:CLSA_RS08715
uniprot id: U5MQI1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1345695:CLSA RS06360
gene id: 1345695:CLSA_RS06360
uniprot id: U5MRK7
names: Similarity
messages: Belongs to the GARS family.

1345695:CLSA RS21740
gene id: 1345695:CLSA_RS21740
uniprot id: U5MY00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1345695:CLSA RS06580
gene id: 1345695:CLSA_RS06580
uniprot id: U5MP27
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS21505
gene id: 1345695:CLSA_RS21505
uniprot id: U5N0Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1345695:CLSA RS09450
gene id: 1345695:CLSA_RS09450
uniprot id: U5MR15
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1345695:CLSA RS05360
gene id: 1345695:CLSA_RS05360
uniprot id: U5MNL5
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1345695:CLSA RS01420
gene id: 1345695:CLSA_RS01420
uniprot id: U5MNS6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1345695:CLSA RS06865
gene id: 1345695:CLSA_RS06865
uniprot id: U5MN47
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1345695:CLSA RS09000
gene id: 1345695:CLSA_RS09000
uniprot id: U5MQP3
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1345695:CLSA RS20770
gene id: 1345695:CLSA_RS20770
uniprot id: U5MXK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1345695:CLSA RS01385
gene id: 1345695:CLSA_RS01385
uniprot id: U5MLC0
names: Similarity
messages: Belongs to the CapA family.

1345695:CLSA RS11915
gene id: 1345695:CLSA_RS11915
uniprot id: U5MRP6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1345695:CLSA RS09170
gene id: 1345695:CLSA_RS09170
uniprot id: U5MQ09
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1345695:CLSA RS13980
gene id: 1345695:CLSA_RS13980
uniprot id: U5MTE0
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1345695:CLSA RS01735
gene id: 1345695:CLSA_RS01735
uniprot id: U5MP34
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1345695:CLSA RS12935
gene id: 1345695:CLSA_RS12935
uniprot id: U5MS71
names: Similarity
messages: Belongs to the TlyA family.

1345695:CLSA RS19255
gene id: 1345695:CLSA_RS19255
uniprot id: U5MW27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS10010
gene id: 1345695:CLSA_RS10010
uniprot id: U5MTR7
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1345695:CLSA RS08415
gene id: 1345695:CLSA_RS08415
uniprot id: U5MTE1
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1345695:CLSA RS11525
gene id: 1345695:CLSA_RS11525
uniprot id: U5MS52
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

1345695:CLSA RS13195
gene id: 1345695:CLSA_RS13195
uniprot id: U5MVN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1345695:CLSA RS20705
gene id: 1345695:CLSA_RS20705
uniprot id: U5MWS6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1345695:CLSA RS13150
gene id: 1345695:CLSA_RS13150
uniprot id: U5MW70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

1345695:CLSA RS13205
gene id: 1345695:CLSA_RS13205
uniprot id: U5MT46
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1345695:CLSA RS05600
gene id: 1345695:CLSA_RS05600
uniprot id: U5MMW7
names: Similarity
messages: Belongs to the GSP E family.

1345695:CLSA RS00435
gene id: 1345695:CLSA_RS00435
uniprot id: U5MKM3
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

1345695:CLSA RS21180
gene id: 1345695:CLSA_RS21180
uniprot id: U5MXQ9
names: Similarity
messages: Belongs to the peptidase M13 family.

1345695:CLSA RS19105
gene id: 1345695:CLSA_RS19105
uniprot id: U5MW02
names: Similarity
messages: Belongs to the FlgM family.

1345695:CLSA RS03520
gene id: 1345695:CLSA_RS03520
uniprot id: U5MMB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS07115
gene id: 1345695:CLSA_RS07115
uniprot id: U5MS45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

1345695:CLSA RS01540
gene id: 1345695:CLSA_RS01540
uniprot id: U5MLI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1345695:CLSA RS01320
gene id: 1345695:CLSA_RS01320
uniprot id: U5MNQ0
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1345695:CLSA RS06710
gene id: 1345695:CLSA_RS06710
uniprot id: U5MRX6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1345695:CLSA RS06405
gene id: 1345695:CLSA_RS06405
uniprot id: U5MNY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1345695:CLSA RS19920
gene id: 1345695:CLSA_RS19920
uniprot id: U5MWC9
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS19370
gene id: 1345695:CLSA_RS19370
uniprot id: U5MWT1
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1345695:CLSA RS09615
gene id: 1345695:CLSA_RS09615
uniprot id: U5MQB5
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1345695:CLSA RS10945
gene id: 1345695:CLSA_RS10945
uniprot id: U5MU98
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS17905
gene id: 1345695:CLSA_RS17905
uniprot id: U5MVW5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1345695:CLSA RS05405
gene id: 1345695:CLSA_RS05405
uniprot id: U5MRR1
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1345695:CLSA RS07765
gene id: 1345695:CLSA_RS07765
uniprot id: U5MP69
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS03585
gene id: 1345695:CLSA_RS03585
uniprot id: U5MMJ0
names: Similarity
messages: Belongs to the ThiD family.

1345695:CLSA RS05910
gene id: 1345695:CLSA_RS05910
uniprot id: U5MNP1
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D-gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP).

1345695:CLSA RS06535
gene id: 1345695:CLSA_RS06535
uniprot id: U5MRP8
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1345695:CLSA RS21735
gene id: 1345695:CLSA_RS21735
uniprot id: U5MXF3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1345695:CLSA RS10630
gene id: 1345695:CLSA_RS10630
uniprot id: U5MU28
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1345695:CLSA RS13735
gene id: 1345695:CLSA_RS13735
uniprot id: U5MW01
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1345695:CLSA RS10530
gene id: 1345695:CLSA_RS10530
uniprot id: U5MUN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1345695:CLSA RS05830
gene id: 1345695:CLSA_RS05830
uniprot id: U5MN11
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1345695:CLSA RS15060
gene id: 1345695:CLSA_RS15060
uniprot id: U5MU37
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1345695:CLSA RS00860
gene id: 1345695:CLSA_RS00860
uniprot id: U5MKT5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1345695:CLSA RS12750
gene id: 1345695:CLSA_RS12750
uniprot id: U5MSM8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer and homodimer.

1345695:CLSA RS01140
gene id: 1345695:CLSA_RS01140
uniprot id: U5MNL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1345695:CLSA RS13180
gene id: 1345695:CLSA_RS13180
uniprot id: U5MT41
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS13395
gene id: 1345695:CLSA_RS13395
uniprot id: U5MSF7
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS21835
gene id: 1345695:CLSA_RS21835
uniprot id: U5MY48
names: Similarity
messages: Belongs to the ParB family.

1345695:CLSA RS01040
gene id: 1345695:CLSA_RS01040
uniprot id: U5MKX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1345695:CLSA RS06335
gene id: 1345695:CLSA_RS06335
uniprot id: U5MRK3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1345695:CLSA RS14755
gene id: 1345695:CLSA_RS14755
uniprot id: U5MX68
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1345695:CLSA RS12360
gene id: 1345695:CLSA_RS12360
uniprot id: U5MSP3
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1345695:CLSA RS18245
gene id: 1345695:CLSA_RS18245
uniprot id: U5MVC1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1345695:CLSA RS12945
gene id: 1345695:CLSA_RS12945
uniprot id: U5MVI6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1345695:CLSA RS05525
gene id: 1345695:CLSA_RS05525
uniprot id: U5MMV5
names: Similarity
messages: Belongs to the acylphosphatase family.

1345695:CLSA RS06855
gene id: 1345695:CLSA_RS06855
uniprot id: U5MPC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1345695:CLSA RS01235
gene id: 1345695:CLSA_RS01235
uniprot id: U5MKF9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1345695:CLSA RS20350
gene id: 1345695:CLSA_RS20350
uniprot id: U5MX66
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS15815
gene id: 1345695:CLSA_RS15815
uniprot id: U5MXQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1345695:CLSA RS07300
gene id: 1345695:CLSA_RS07300
uniprot id: U5MPJ7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS00010
gene id: 1345695:CLSA_RS00010
uniprot id: U5MKF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1345695:CLSA RS02520
gene id: 1345695:CLSA_RS02520
uniprot id: U5ML69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1345695:CLSA RS14960
gene id: 1345695:CLSA_RS14960
uniprot id: U5MU16
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1345695:CLSA RS13820
gene id: 1345695:CLSA_RS13820
uniprot id: U5MTG6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1345695:CLSA RS01655
gene id: 1345695:CLSA_RS01655
uniprot id: U5MKU3
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS11395
gene id: 1345695:CLSA_RS11395
uniprot id: U5MUJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1345695:CLSA RS06895
gene id: 1345695:CLSA_RS06895
uniprot id: U5MPK0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1345695:CLSA RS12720
gene id: 1345695:CLSA_RS12720
uniprot id: U5MS31
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1345695:CLSA RS09025
gene id: 1345695:CLSA_RS09025
uniprot id: U5MQP7
names: Similarity
messages: Belongs to the ArsC family.

1345695:CLSA RS06595
gene id: 1345695:CLSA_RS06595
uniprot id: U5MP99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1345695:CLSA RS13915
gene id: 1345695:CLSA_RS13915
uniprot id: U5MTI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

1345695:CLSA RS01860
gene id: 1345695:CLSA_RS01860
uniprot id: U5MP56
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1345695:CLSA RS06610
gene id: 1345695:CLSA_RS06610
uniprot id: U5MRR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1345695:CLSA RS14775
gene id: 1345695:CLSA_RS14775
uniprot id: U5MWN6
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.

1345695:CLSA RS08440
gene id: 1345695:CLSA_RS08440
uniprot id: U5MST4
names: Similarity
messages: Belongs to the peptidase S66 family.

1345695:CLSA RS12685
gene id: 1345695:CLSA_RS12685
uniprot id: U5MVX9
names: Similarity
messages: Belongs to the peptidase S11 family.

1345695:CLSA RS09510
gene id: 1345695:CLSA_RS09510
uniprot id: U5MQU2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1345695:CLSA RS21760
gene id: 1345695:CLSA_RS21760
uniprot id: U5MY37
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1345695:CLSA RS12270
gene id: 1345695:CLSA_RS12270
uniprot id: U5MV48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS11070
gene id: 1345695:CLSA_RS11070
uniprot id: U5MRW0
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1345695:CLSA RS10730
gene id: 1345695:CLSA_RS10730
uniprot id: U5MRP5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1345695:CLSA RS14905
gene id: 1345695:CLSA_RS14905
uniprot id: U5MU71
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1345695:CLSA RS01300
gene id: 1345695:CLSA_RS01300
uniprot id: U5MPD8
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1345695:CLSA RS02790
gene id: 1345695:CLSA_RS02790
uniprot id: U5MQ87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

1345695:CLSA RS14830
gene id: 1345695:CLSA_RS14830
uniprot id: U5MX78
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

1345695:CLSA RS07135
gene id: 1345695:CLSA_RS07135
uniprot id: U5MNW2
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1345695:CLSA RS01415
gene id: 1345695:CLSA_RS01415
uniprot id: U5ML51
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1345695:CLSA RS19385
gene id: 1345695:CLSA_RS19385
uniprot id: U5MZR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS11940
gene id: 1345695:CLSA_RS11940
uniprot id: U5MRQ0
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1345695:CLSA RS14275
gene id: 1345695:CLSA_RS14275
uniprot id: U5MWE4
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1345695:CLSA RS02995
gene id: 1345695:CLSA_RS02995
uniprot id: U5MM03
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS15005
gene id: 1345695:CLSA_RS15005
uniprot id: U5MTI1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1345695:CLSA RS04425
gene id: 1345695:CLSA_RS04425
uniprot id: U5MMC3
names: Similarity
messages: Belongs to the HsdR family.

1345695:CLSA RS14715
gene id: 1345695:CLSA_RS14715
uniprot id: U5MTD3
names: Similarity
messages: Belongs to the UPF0473 family.

1345695:CLSA RS15010
gene id: 1345695:CLSA_RS15010
uniprot id: U5MU25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1345695:CLSA RS09525
gene id: 1345695:CLSA_RS09525
uniprot id: U5MQA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1345695:CLSA RS08585
gene id: 1345695:CLSA_RS08585
uniprot id: U5MSW4
names: Similarity
messages: Belongs to the DEAD box helicase family.

1345695:CLSA RS08810
gene id: 1345695:CLSA_RS08810
uniprot id: U5MQK2
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

1345695:CLSA RS11865
gene id: 1345695:CLSA_RS11865
uniprot id: U5MSF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS13575
gene id: 1345695:CLSA_RS13575
uniprot id: U5MWE2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1345695:CLSA RS09035
gene id: 1345695:CLSA_RS09035
uniprot id: U5MQI0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1345695:CLSA RS07180
gene id: 1345695:CLSA_RS07180
uniprot id: U5MPN8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1345695:CLSA RS13495
gene id: 1345695:CLSA_RS13495
uniprot id: U5MVU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1345695:CLSA RS14965
gene id: 1345695:CLSA_RS14965
uniprot id: U5MWS3
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1345695:CLSA RS06820
gene id: 1345695:CLSA_RS06820
uniprot id: U5MPI8
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

1345695:CLSA RS13890
gene id: 1345695:CLSA_RS13890
uniprot id: U5MWK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1345695:CLSA RS00555
gene id: 1345695:CLSA_RS00555
uniprot id: U5MK40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1345695:CLSA RS10880
gene id: 1345695:CLSA_RS10880
uniprot id: U5MRI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1345695:CLSA RS08825
gene id: 1345695:CLSA_RS08825
uniprot id: U5MT13
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1345695:CLSA RS09900
gene id: 1345695:CLSA_RS09900
uniprot id: U5MRA0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS00970
gene id: 1345695:CLSA_RS00970
uniprot id: U5MNI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1345695:CLSA RS03260
gene id: 1345695:CLSA_RS03260
uniprot id: U5MMC4
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

1345695:CLSA RS20865
gene id: 1345695:CLSA_RS20865
uniprot id: U5MN47
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1345695:CLSA RS09835
gene id: 1345695:CLSA_RS09835
uniprot id: U5MQF0
names: Similarity
messages: Belongs to the EamA transporter family.

1345695:CLSA RS13740
gene id: 1345695:CLSA_RS13740
uniprot id: U5MWH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1345695:CLSA RS10835
gene id: 1345695:CLSA_RS10835
uniprot id: U5MQY1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1345695:CLSA RS19550
gene id: 1345695:CLSA_RS19550
uniprot id: U5MZD3
names: Similarity
messages: Belongs to the UPF0229 family.

1345695:CLSA RS08000
gene id: 1345695:CLSA_RS08000
uniprot id: U5MQ40
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

1345695:CLSA RS01135
gene id: 1345695:CLSA_RS01135
uniprot id: U5MKZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1345695:CLSA RS03475
gene id: 1345695:CLSA_RS03475
uniprot id: U5MM97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS19600
gene id: 1345695:CLSA_RS19600
uniprot id: U5MZE0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1345695:CLSA RS04865
gene id: 1345695:CLSA_RS04865
uniprot id: U5MRG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1345695:CLSA RS00585
gene id: 1345695:CLSA_RS00585
uniprot id: U5MKQ2
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS04365
gene id: 1345695:CLSA_RS04365
uniprot id: U5MQI3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1345695:CLSA RS06340
gene id: 1345695:CLSA_RS06340
uniprot id: U5MS77
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1345695:CLSA RS03690
gene id: 1345695:CLSA_RS03690
uniprot id: U5MLT5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

1345695:CLSA RS17985
gene id: 1345695:CLSA_RS17985
uniprot id: U5MVY1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1345695:CLSA RS20825
gene id: 1345695:CLSA_RS20825
uniprot id: U5MXH4
names: Similarity
messages: Belongs to the helicase family. RAD3/XPD subfamily.

1345695:CLSA RS03340
gene id: 1345695:CLSA_RS03340
uniprot id: U5MM68
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1345695:CLSA RS18675
gene id: 1345695:CLSA_RS18675
uniprot id: U5MVM4
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1345695:CLSA RS08905
gene id: 1345695:CLSA_RS08905
uniprot id: U5MQM2
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1345695:CLSA RS05080
gene id: 1345695:CLSA_RS05080
uniprot id: U5MQV3
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS03240
gene id: 1345695:CLSA_RS03240
uniprot id: U5MMB9
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

1345695:CLSA RS18115
gene id: 1345695:CLSA_RS18115
uniprot id: U5MW04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1345695:CLSA RS06010
gene id: 1345695:CLSA_RS06010
uniprot id: U5MNR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1345695:CLSA RS08475
gene id: 1345695:CLSA_RS08475
uniprot id: U5MQD1
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1345695:CLSA RS17450
gene id: 1345695:CLSA_RS17450
uniprot id: U5MUX8
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

1345695:CLSA RS03030
gene id: 1345695:CLSA_RS03030
uniprot id: U5MPL5
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

1345695:CLSA RS09750
gene id: 1345695:CLSA_RS09750
uniprot id: U5MR69
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS03710
gene id: 1345695:CLSA_RS03710
uniprot id: U5MML8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1345695:CLSA RS01370
gene id: 1345695:CLSA_RS01370
uniprot id: U5ML42
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1345695:CLSA RS04775
gene id: 1345695:CLSA_RS04775
uniprot id: U5MNA8
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1345695:CLSA RS20335
gene id: 1345695:CLSA_RS20335
uniprot id: U5N072
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1345695:CLSA RS00535
gene id: 1345695:CLSA_RS00535
uniprot id: U5MKP4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1345695:CLSA RS05345
gene id: 1345695:CLSA_RS05345
uniprot id: U5MND7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1345695:CLSA RS03355
gene id: 1345695:CLSA_RS03355
uniprot id: U5MME4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS06915
gene id: 1345695:CLSA_RS06915
uniprot id: U5MSN5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1345695:CLSA RS18200
gene id: 1345695:CLSA_RS18200
uniprot id: U5MVW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1345695:CLSA RS03530
gene id: 1345695:CLSA_RS03530
uniprot id: U5MQM3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1345695:CLSA RS04275
gene id: 1345695:CLSA_RS04275
uniprot id: U5MN22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
messages: Homodimer.
messages: Involved in phosphonate degradation.

1345695:CLSA RS08285
gene id: 1345695:CLSA_RS08285
uniprot id: U5MQ27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS19430
gene id: 1345695:CLSA_RS19430
uniprot id: U5MZB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1345695:CLSA RS08850
gene id: 1345695:CLSA_RS08850
uniprot id: U5MT18
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

1345695:CLSA RS21210
gene id: 1345695:CLSA_RS21210
uniprot id: U5MX26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1345695:CLSA RS11820
gene id: 1345695:CLSA_RS11820
uniprot id: U5MRM9
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS15600
gene id: 1345695:CLSA_RS15600
uniprot id: U5MUE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1345695:CLSA RS17915
gene id: 1345695:CLSA_RS17915
uniprot id: U5MVR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1345695:CLSA RS06575
gene id: 1345695:CLSA_RS06575
uniprot id: U5MNG8
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1345695:CLSA RS02460
gene id: 1345695:CLSA_RS02460
uniprot id: U5MLY3
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1345695:CLSA RS07615
gene id: 1345695:CLSA_RS07615
uniprot id: U5MPX2
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1345695:CLSA RS14680
gene id: 1345695:CLSA_RS14680
uniprot id: U5MU24
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS12710
gene id: 1345695:CLSA_RS12710
uniprot id: U5MVY5
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1345695:CLSA RS15395
gene id: 1345695:CLSA_RS15395
uniprot id: U5MUA4
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1345695:CLSA RS15520
gene id: 1345695:CLSA_RS15520
uniprot id: U5MTT3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS07075
gene id: 1345695:CLSA_RS07075
uniprot id: U5MPM5
names: Similarity
messages: Belongs to the peptidase M16 family.

1345695:CLSA RS18750
gene id: 1345695:CLSA_RS18750
uniprot id: U5MYX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1345695:CLSA RS18780
gene id: 1345695:CLSA_RS18780
uniprot id: U5MZD2
names: Similarity
messages: Belongs to the universal stress protein A family.

1345695:CLSA RS06510
gene id: 1345695:CLSA_RS06510
uniprot id: U5MRP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1345695:CLSA RS15090
gene id: 1345695:CLSA_RS15090
uniprot id: U5MXC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1345695:CLSA RS13455
gene id: 1345695:CLSA_RS13455
uniprot id: U5MT94
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS20340
gene id: 1345695:CLSA_RS20340
uniprot id: U5MXB5
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1345695:CLSA RS10040
gene id: 1345695:CLSA_RS10040
uniprot id: U5MUE3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1345695:CLSA RS13110
gene id: 1345695:CLSA_RS13110
uniprot id: U5MSA2
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

1345695:CLSA RS11390
gene id: 1345695:CLSA_RS11390
uniprot id: U5MRU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1345695:CLSA RS00705
gene id: 1345695:CLSA_RS00705
uniprot id: U5MK61
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1345695:CLSA RS18715
gene id: 1345695:CLSA_RS18715
uniprot id: U5MWC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1345695:CLSA RS07040
gene id: 1345695:CLSA_RS07040
uniprot id: U5MS32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1345695:CLSA RS24065
gene id: 1345695:CLSA_RS24065
uniprot id: U5MTV7
names: Similarity
messages: Belongs to the peptidase C40 family.

1345695:CLSA RS09125
gene id: 1345695:CLSA_RS09125
uniprot id: U5MQI9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1345695:CLSA RS18480
gene id: 1345695:CLSA_RS18480
uniprot id: U5MZ52
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS02170
gene id: 1345695:CLSA_RS02170
uniprot id: U5MPZ0
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1345695:CLSA RS01065
gene id: 1345695:CLSA_RS01065
uniprot id: U5MNK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1345695:CLSA RS09270
gene id: 1345695:CLSA_RS09270
uniprot id: U5MQY0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1345695:CLSA RS01795
gene id: 1345695:CLSA_RS01795
uniprot id: U5MLP2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1345695:CLSA RS14935
gene id: 1345695:CLSA_RS14935
uniprot id: U5MU10
names: Similarity
messages: Belongs to the Fur family.

1345695:CLSA RS15035
gene id: 1345695:CLSA_RS15035
uniprot id: U5MU30
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1345695:CLSA RS00455
gene id: 1345695:CLSA_RS00455
uniprot id: U5MK21
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1345695:CLSA RS05930
gene id: 1345695:CLSA_RS05930
uniprot id: U5MN34
names: Function
names: Similarity
messages: Belongs to the IolE/MocC family.
messages: Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).

1345695:CLSA RS10755
gene id: 1345695:CLSA_RS10755
uniprot id: U5MRQ1
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1345695:CLSA RS05075
gene id: 1345695:CLSA_RS05075
uniprot id: U5MN90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1345695:CLSA RS18855
gene id: 1345695:CLSA_RS18855
uniprot id: U5MWJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

1345695:CLSA RS07620
gene id: 1345695:CLSA_RS07620
uniprot id: U5MP46
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS19775
gene id: 1345695:CLSA_RS19775
uniprot id: U5MWA3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1345695:CLSA RS10575
gene id: 1345695:CLSA_RS10575
uniprot id: U5MQS7
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1345695:CLSA RS18190
gene id: 1345695:CLSA_RS18190
uniprot id: U5MW20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1345695:CLSA RS07635
gene id: 1345695:CLSA_RS07635
uniprot id: U5MSZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1345695:CLSA RS07755
gene id: 1345695:CLSA_RS07755
uniprot id: U5MT14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

1345695:CLSA RS06930
gene id: 1345695:CLSA_RS06930
uniprot id: U5MPD2
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS07310
gene id: 1345695:CLSA_RS07310
uniprot id: U5MSU1
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1345695:CLSA RS06240
gene id: 1345695:CLSA_RS06240
uniprot id: U5MS58
names: Similarity
messages: Belongs to the asparagine synthetase family.

1345695:CLSA RS06515
gene id: 1345695:CLSA_RS06515
uniprot id: U5MSB1
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1345695:CLSA RS19525
gene id: 1345695:CLSA_RS19525
uniprot id: U5MZC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1345695:CLSA RS05870
gene id: 1345695:CLSA_RS05870
uniprot id: U5MRY7
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS21480
gene id: 1345695:CLSA_RS21480
uniprot id: U5N0H7
names: Subcellular Location Annotation
messages: Cytoplasm

1345695:CLSA RS01130
gene id: 1345695:CLSA_RS01130
uniprot id: U5MKE1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1345695:CLSA RS14800
gene id: 1345695:CLSA_RS14800
uniprot id: U5MWP0
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1345695:CLSA RS04710
gene id: 1345695:CLSA_RS04710
uniprot id: U5MQN6
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS15020
gene id: 1345695:CLSA_RS15020
uniprot id: U5MXB4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1345695:CLSA RS11765
gene id: 1345695:CLSA_RS11765
uniprot id: U5MSE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
messages: Cytoplasm

1345695:CLSA RS08570
gene id: 1345695:CLSA_RS08570
uniprot id: U5MQE9
names: Function
names: Similarity
messages: Belongs to the LarC family.
messages: Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.

1345695:CLSA RS00465
gene id: 1345695:CLSA_RS00465
uniprot id: U5MN96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1345695:CLSA RS06810
gene id: 1345695:CLSA_RS06810
uniprot id: U5MRZ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1345695:CLSA RS14630
gene id: 1345695:CLSA_RS14630
uniprot id: U5MU17
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.

1345695:CLSA RS15460
gene id: 1345695:CLSA_RS15460
uniprot id: U5MUB6
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1345695:CLSA RS03540
gene id: 1345695:CLSA_RS03540
uniprot id: U5MLQ5
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1345695:CLSA RS19790
gene id: 1345695:CLSA_RS19790
uniprot id: U5MZX7
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1345695:CLSA RS20665
gene id: 1345695:CLSA_RS20665
uniprot id: U5MXD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1345695:CLSA RS15025
gene id: 1345695:CLSA_RS15025
uniprot id: U5MU95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1345695:CLSA RS06070
gene id: 1345695:CLSA_RS06070
uniprot id: U5MNZ5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1345695:CLSA RS00550
gene id: 1345695:CLSA_RS00550
uniprot id: U5MKX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1345695:CLSA RS12645
gene id: 1345695:CLSA_RS12645
uniprot id: U5MS16
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1345695:CLSA RS10650
gene id: 1345695:CLSA_RS10650
uniprot id: U5MUQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS13190
gene id: 1345695:CLSA_RS13190
uniprot id: U5MSY3
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS18960
gene id: 1345695:CLSA_RS18960
uniprot id: U5MWF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1345695:CLSA RS20160
gene id: 1345695:CLSA_RS20160
uniprot id: U5MX28
names: Similarity
messages: Belongs to the HepT RNase toxin family.

1345695:CLSA RS01035
gene id: 1345695:CLSA_RS01035
uniprot id: U5MKC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1345695:CLSA RS07515
gene id: 1345695:CLSA_RS07515
uniprot id: U5MPV1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1345695:CLSA RS18640
gene id: 1345695:CLSA_RS18640
uniprot id: U5MZ81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1345695:CLSA RS06785
gene id: 1345695:CLSA_RS06785
uniprot id: U5MRZ0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1345695:CLSA RS01050
gene id: 1345695:CLSA_RS01050
uniprot id: U5MP89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1345695:CLSA RS16135
gene id: 1345695:CLSA_RS16135
uniprot id: U5MU53
names: Function
names: Similarity
messages: Belongs to the ADC family.
messages: Catalyzes the conversion of acetoacetate to acetone and carbon dioxide.

1345695:CLSA RS20840
gene id: 1345695:CLSA_RS20840
uniprot id: U5MXL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1345695:CLSA RS09260
gene id: 1345695:CLSA_RS09260
uniprot id: U5MTD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1345695:CLSA RS04705
gene id: 1345695:CLSA_RS04705
uniprot id: U5MN26
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.

1345695:CLSA RS03375
gene id: 1345695:CLSA_RS03375
uniprot id: U5MME9
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1345695:CLSA RS18435
gene id: 1345695:CLSA_RS18435
uniprot id: U5MW71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS01045
gene id: 1345695:CLSA_RS01045
uniprot id: U5MNJ6
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1345695:CLSA RS10965
gene id: 1345695:CLSA_RS10965
uniprot id: U5MRK1
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

1345695:CLSA RS21945
gene id: 1345695:CLSA_RS21945
uniprot id: U5MQR0
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1345695:CLSA RS00790
gene id: 1345695:CLSA_RS00790
uniprot id: U5MNE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1345695:CLSA RS19440
gene id: 1345695:CLSA_RS19440
uniprot id: U5MWU7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1345695:CLSA RS13465
gene id: 1345695:CLSA_RS13465
uniprot id: U5MT36
names: Similarity
messages: Belongs to the asparaginase 1 family.

1345695:CLSA RS03665
gene id: 1345695:CLSA_RS03665
uniprot id: U5MLT0
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS20565
gene id: 1345695:CLSA_RS20565
uniprot id: U5MWQ0
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS05475
gene id: 1345695:CLSA_RS05475
uniprot id: U5MMU5
names: Similarity
messages: Belongs to the peptidase S8 family.

1345695:CLSA RS12805
gene id: 1345695:CLSA_RS12805
uniprot id: U5MVF5
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1345695:CLSA RS06815
gene id: 1345695:CLSA_RS06815
uniprot id: U5MSL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1345695:CLSA RS18925
gene id: 1345695:CLSA_RS18925
uniprot id: U5MZH5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1345695:CLSA RS02080
gene id: 1345695:CLSA_RS02080
uniprot id: U5MPX4
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1345695:CLSA RS01430
gene id: 1345695:CLSA_RS01430
uniprot id: U5MLD0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1345695:CLSA RS21520
gene id: 1345695:CLSA_RS21520
uniprot id: U5N0I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS21345
gene id: 1345695:CLSA_RS21345
uniprot id: U5N0U7
names: Similarity
messages: Belongs to the peptidase S66 family.

1345695:CLSA RS01125
gene id: 1345695:CLSA_RS01125
uniprot id: U5ML66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1345695:CLSA RS08595
gene id: 1345695:CLSA_RS08595
uniprot id: U5MQF4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1345695:CLSA RS11470
gene id: 1345695:CLSA_RS11470
uniprot id: U5MV57
names: Similarity
messages: Belongs to the peptidase S24 family.

1345695:CLSA RS00115
gene id: 1345695:CLSA_RS00115
uniprot id: U5MNU2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of AddA and AddB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.

1345695:CLSA RS01630
gene id: 1345695:CLSA_RS01630
uniprot id: U5MKT8
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1345695:CLSA RS15325
gene id: 1345695:CLSA_RS15325
uniprot id: U5MXH9
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1345695:CLSA RS06350
gene id: 1345695:CLSA_RS06350
uniprot id: U5MNB8
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS12650
gene id: 1345695:CLSA_RS12650
uniprot id: U5MSK9
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS05170
gene id: 1345695:CLSA_RS05170
uniprot id: U5MMP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1345695:CLSA RS06355
gene id: 1345695:CLSA_RS06355
uniprot id: U5MNY0
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1345695:CLSA RS06725
gene id: 1345695:CLSA_RS06725
uniprot id: U5MNP2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1345695:CLSA RS02800
gene id: 1345695:CLSA_RS02800
uniprot id: U5MLB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1345695:CLSA RS08615
gene id: 1345695:CLSA_RS08615
uniprot id: U5MQG0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. SigI subfamily.
messages: Cytoplasm
messages: Interacts with RsgI.
messages: Negatively regulated by the anti-sigma-I factor RsgI.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1345695:CLSA RS07555
gene id: 1345695:CLSA_RS07555
uniprot id: U5MSY0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1345695:CLSA RS19925
gene id: 1345695:CLSA_RS19925
uniprot id: U5MWX8
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1345695:CLSA RS05675
gene id: 1345695:CLSA_RS05675
uniprot id: U5MMY1
names: Similarity
messages: Belongs to the glutamate synthase family.

1345695:CLSA RS10380
gene id: 1345695:CLSA_RS10380
uniprot id: U5MRH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases.
messages: Periplasm
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

1345695:CLSA RS07975
gene id: 1345695:CLSA_RS07975
uniprot id: U5MQ36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS15730
gene id: 1345695:CLSA_RS15730
uniprot id: U5MUG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

1345695:CLSA RS18590
gene id: 1345695:CLSA_RS18590
uniprot id: U5MZ73
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1345695:CLSA RS16740
gene id: 1345695:CLSA_RS16740
uniprot id: U5MV47
names: Function
messages: Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase.

1345695:CLSA RS18870
gene id: 1345695:CLSA_RS18870
uniprot id: U5MZ33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1345695:CLSA RS10615
gene id: 1345695:CLSA_RS10615
uniprot id: U5MRL9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS05270
gene id: 1345695:CLSA_RS05270
uniprot id: U5MNC2
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1345695:CLSA RS07390
gene id: 1345695:CLSA_RS07390
uniprot id: U5MPS8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1345695:CLSA RS19230
gene id: 1345695:CLSA_RS19230
uniprot id: U5MW22
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS06305
gene id: 1345695:CLSA_RS06305
uniprot id: U5MNX2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1345695:CLSA RS01170
gene id: 1345695:CLSA_RS01170
uniprot id: U5MPB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

1345695:CLSA RS19380
gene id: 1345695:CLSA_RS19380
uniprot id: U5MZA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1345695:CLSA RS21870
gene id: 1345695:CLSA_RS21870
uniprot id: U5MY17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1345695:CLSA RS12565
gene id: 1345695:CLSA_RS12565
uniprot id: U5MVV7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1345695:CLSA RS01160
gene id: 1345695:CLSA_RS01160
uniprot id: U5ML01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS15675
gene id: 1345695:CLSA_RS15675
uniprot id: U5MTV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1345695:CLSA RS00495
gene id: 1345695:CLSA_RS00495
uniprot id: U5MN47
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1345695:CLSA RS04930
gene id: 1345695:CLSA_RS04930
uniprot id: U5MN69
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1345695:CLSA RS00530
gene id: 1345695:CLSA_RS00530
uniprot id: U5MK35
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS18900
gene id: 1345695:CLSA_RS18900
uniprot id: U5MZH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS06560
gene id: 1345695:CLSA_RS06560
uniprot id: U5MRQ3
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1345695:CLSA RS21725
gene id: 1345695:CLSA_RS21725
uniprot id: U5N123
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

1345695:CLSA RS09745
gene id: 1345695:CLSA_RS09745
uniprot id: U5MU97
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS21465
gene id: 1345695:CLSA_RS21465
uniprot id: U5MXZ8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1345695:CLSA RS00445
gene id: 1345695:CLSA_RS00445
uniprot id: U5MNZ6
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

1345695:CLSA RS08815
gene id: 1345695:CLSA_RS08815
uniprot id: U5MPR7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1345695:CLSA RS11670
gene id: 1345695:CLSA_RS11670
uniprot id: U5MSC2
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1345695:CLSA RS21840
gene id: 1345695:CLSA_RS21840
uniprot id: U5MXH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1345695:CLSA RS02550
gene id: 1345695:CLSA_RS02550
uniprot id: U5MLS8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS02430
gene id: 1345695:CLSA_RS02430
uniprot id: U5MQ25
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1345695:CLSA RS13485
gene id: 1345695:CLSA_RS13485
uniprot id: U5MSH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1345695:CLSA RS00305
gene id: 1345695:CLSA_RS00305
uniprot id: U5MKJ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1345695:CLSA RS00085
gene id: 1345695:CLSA_RS00085
uniprot id: U5MKG0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS02745
gene id: 1345695:CLSA_RS02745
uniprot id: U5MM32
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1345695:CLSA RS01080
gene id: 1345695:CLSA_RS01080
uniprot id: U5MKD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1345695:CLSA RS15710
gene id: 1345695:CLSA_RS15710
uniprot id: U5MX81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1345695:CLSA RS13340
gene id: 1345695:CLSA_RS13340
uniprot id: U5MSE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1345695:CLSA RS04605
gene id: 1345695:CLSA_RS04605
uniprot id: U5MMF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1345695:CLSA RS11895
gene id: 1345695:CLSA_RS11895
uniprot id: U5MRP1
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS10390
gene id: 1345695:CLSA_RS10390
uniprot id: U5MQP4
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS13090
gene id: 1345695:CLSA_RS13090
uniprot id: U5MSW6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS03780
gene id: 1345695:CLSA_RS03780
uniprot id: U5MMN3
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1345695:CLSA RS01105
gene id: 1345695:CLSA_RS01105
uniprot id: U5MKD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1345695:CLSA RS02090
gene id: 1345695:CLSA_RS02090
uniprot id: U5ML06
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS09110
gene id: 1345695:CLSA_RS09110
uniprot id: U5MTS5
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS06775
gene id: 1345695:CLSA_RS06775
uniprot id: U5MNQ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1345695:CLSA RS06485
gene id: 1345695:CLSA_RS06485
uniprot id: U5MRN8
names: Similarity
messages: Belongs to the UPF0297 family.

1345695:CLSA RS10475
gene id: 1345695:CLSA_RS10475
uniprot id: U5MRB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS18520
gene id: 1345695:CLSA_RS18520
uniprot id: U5MYS6
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1345695:CLSA RS07630
gene id: 1345695:CLSA_RS07630
uniprot id: U5MSD6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
messages: Homodimer.

1345695:CLSA RS17480
gene id: 1345695:CLSA_RS17480
uniprot id: U5MY84
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS19175
gene id: 1345695:CLSA_RS19175
uniprot id: U5MWQ1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1345695:CLSA RS02490
gene id: 1345695:CLSA_RS02490
uniprot id: U5MLY6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1345695:CLSA RS03345
gene id: 1345695:CLSA_RS03345
uniprot id: U5MPS6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

1345695:CLSA RS00505
gene id: 1345695:CLSA_RS00505
uniprot id: U5MK31
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1345695:CLSA RS02600
gene id: 1345695:CLSA_RS02600
uniprot id: U5MM01
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1345695:CLSA RS09710
gene id: 1345695:CLSA_RS09710
uniprot id: U5MQX7
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1345695:CLSA RS03720
gene id: 1345695:CLSA_RS03720
uniprot id: U5MMF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS02425
gene id: 1345695:CLSA_RS02425
uniprot id: U5MPC4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1345695:CLSA RS04210
gene id: 1345695:CLSA_RS04210
uniprot id: U5MQF2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1345695:CLSA RS10510
gene id: 1345695:CLSA_RS10510
uniprot id: U5MUM8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS06330
gene id: 1345695:CLSA_RS06330
uniprot id: U5MNX6
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1345695:CLSA RS13855
gene id: 1345695:CLSA_RS13855
uniprot id: U5MTB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1345695:CLSA RS04395
gene id: 1345695:CLSA_RS04395
uniprot id: U5MN47
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1345695:CLSA RS12165
gene id: 1345695:CLSA_RS12165
uniprot id: U5MV26
names: Similarity
messages: Belongs to the manganese catalase family.

1345695:CLSA RS06880
gene id: 1345695:CLSA_RS06880
uniprot id: U5MPC6
names: Similarity
messages: Belongs to the DprA/Smf family.

1345695:CLSA RS19260
gene id: 1345695:CLSA_RS19260
uniprot id: U5MWK7
names: Similarity
messages: Belongs to the Fur family.

1345695:CLSA RS00875
gene id: 1345695:CLSA_RS00875
uniprot id: U5ML20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

1345695:CLSA RS01700
gene id: 1345695:CLSA_RS01700
uniprot id: U5MKV3
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1345695:CLSA RS01185
gene id: 1345695:CLSA_RS01185
uniprot id: U5ML08
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1345695:CLSA RS19335
gene id: 1345695:CLSA_RS19335
uniprot id: U5MWM1
names: Similarity
messages: Belongs to the peptidase S58 family.

1345695:CLSA RS01730
gene id: 1345695:CLSA_RS01730
uniprot id: U5MLF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1345695:CLSA RS10150
gene id: 1345695:CLSA_RS10150
uniprot id: U5MUG2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS01095
gene id: 1345695:CLSA_RS01095
uniprot id: U5MPA1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1345695:CLSA RS02730
gene id: 1345695:CLSA_RS02730
uniprot id: U5MLV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1345695:CLSA RS00235
gene id: 1345695:CLSA_RS00235
uniprot id: U5MN57
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1345695:CLSA RS07890
gene id: 1345695:CLSA_RS07890
uniprot id: U5MPW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1345695:CLSA RS02990
gene id: 1345695:CLSA_RS02990
uniprot id: U5MLE0
names: Similarity
messages: Belongs to the UPF0758 family.

1345695:CLSA RS05200
gene id: 1345695:CLSA_RS05200
uniprot id: U5MNB0
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1345695:CLSA RS20545
gene id: 1345695:CLSA_RS20545
uniprot id: U5MXA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS19575
gene id: 1345695:CLSA_RS19575
uniprot id: U5MZD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1345695:CLSA RS20750
gene id: 1345695:CLSA_RS20750
uniprot id: U5MXJ6
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

1345695:CLSA RS12610
gene id: 1345695:CLSA_RS12610
uniprot id: U5MVW4
names: Similarity
messages: Belongs to the transpeptidase family.

1345695:CLSA RS02975
gene id: 1345695:CLSA_RS02975
uniprot id: U5MPK6
names: Similarity
messages: Belongs to the peptidase C40 family.

1345695:CLSA RS23210
gene id: 1345695:CLSA_RS23210
uniprot id: U5MVX1
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1345695:CLSA RS03020
gene id: 1345695:CLSA_RS03020
uniprot id: U5MLE5
names: Similarity
messages: Belongs to the SfsA family.

1345695:CLSA RS19235
gene id: 1345695:CLSA_RS19235
uniprot id: U5MWK2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1345695:CLSA RS19520
gene id: 1345695:CLSA_RS19520
uniprot id: U5MWQ5
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1345695:CLSA RS01375
gene id: 1345695:CLSA_RS01375
uniprot id: U5MNR3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS21645
gene id: 1345695:CLSA_RS21645
uniprot id: U5MXE0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1345695:CLSA RS18350
gene id: 1345695:CLSA_RS18350
uniprot id: U5MYP0
names: Similarity
messages: Belongs to the YjdM family.

1345695:CLSA RS09970
gene id: 1345695:CLSA_RS09970
uniprot id: U5MUD2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1345695:CLSA RS12065
gene id: 1345695:CLSA_RS12065
uniprot id: U5MRS3
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1345695:CLSA RS19080
gene id: 1345695:CLSA_RS19080
uniprot id: U5MVZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1345695:CLSA RS10815
gene id: 1345695:CLSA_RS10815
uniprot id: U5MRH4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1345695:CLSA RS08235
gene id: 1345695:CLSA_RS08235
uniprot id: U5MQ19
names: Similarity
messages: Belongs to the thioesterase family.

1345695:CLSA RS03185
gene id: 1345695:CLSA_RS03185
uniprot id: U5MQF1
names: Similarity
messages: Belongs to the peptidase S11 family.

1345695:CLSA RS13875
gene id: 1345695:CLSA_RS13875
uniprot id: U5MST1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1345695:CLSA RS01815
gene id: 1345695:CLSA_RS01815
uniprot id: U5MPU5
names: Similarity
messages: Belongs to the UPF0178 family.

1345695:CLSA RS01565
gene id: 1345695:CLSA_RS01565
uniprot id: U5MLK1
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1345695:CLSA RS02065
gene id: 1345695:CLSA_RS02065
uniprot id: U5MLS1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

1345695:CLSA RS14885
gene id: 1345695:CLSA_RS14885
uniprot id: U5MTF9
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS17425
gene id: 1345695:CLSA_RS17425
uniprot id: U5MUX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1345695:CLSA RS06740
gene id: 1345695:CLSA_RS06740
uniprot id: U5MSK3
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1345695:CLSA RS07165
gene id: 1345695:CLSA_RS07165
uniprot id: U5MPH0
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1345695:CLSA RS13265
gene id: 1345695:CLSA_RS13265
uniprot id: U5MSD1
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

1345695:CLSA RS08160
gene id: 1345695:CLSA_RS08160
uniprot id: U5MSN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS00830
gene id: 1345695:CLSA_RS00830
uniprot id: U5MK77
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1345695:CLSA RS13360
gene id: 1345695:CLSA_RS13360
uniprot id: U5MWA0
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS06385
gene id: 1345695:CLSA_RS06385
uniprot id: U5MRL4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1345695:CLSA RS16355
gene id: 1345695:CLSA_RS16355
uniprot id: U5MUW9
names: Similarity
messages: Belongs to the YciI family.

1345695:CLSA RS03275
gene id: 1345695:CLSA_RS03275
uniprot id: U5MPQ8
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

1345695:CLSA RS00195
gene id: 1345695:CLSA_RS00195
uniprot id: U5MNV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1345695:CLSA RS19940
gene id: 1345695:CLSA_RS19940
uniprot id: U5MX42
names: Similarity
messages: Belongs to the EamA transporter family.

1345695:CLSA RS10065
gene id: 1345695:CLSA_RS10065
uniprot id: U5MUE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1345695:CLSA RS18380
gene id: 1345695:CLSA_RS18380
uniprot id: U5MYP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1345695:CLSA RS02385
gene id: 1345695:CLSA_RS02385
uniprot id: U5MLW5
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1345695:CLSA RS10940
gene id: 1345695:CLSA_RS10940
uniprot id: U5MRJ6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1345695:CLSA RS07145
gene id: 1345695:CLSA_RS07145
uniprot id: U5MS50
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS06650
gene id: 1345695:CLSA_RS06650
uniprot id: U5MNI3
names: Similarity
messages: Belongs to the RemA family.

1345695:CLSA RS05115
gene id: 1345695:CLSA_RS05115
uniprot id: U5MNH1
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1345695:CLSA RS15430
gene id: 1345695:CLSA_RS15430
uniprot id: U5MTR2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS19165
gene id: 1345695:CLSA_RS19165
uniprot id: U5MZ76
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1345695:CLSA RS13270
gene id: 1345695:CLSA_RS13270
uniprot id: U5MSZ5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS01340
gene id: 1345695:CLSA_RS01340
uniprot id: U5MKH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1345695:CLSA RS20680
gene id: 1345695:CLSA_RS20680
uniprot id: U5MWS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1345695:CLSA RS19210
gene id: 1345695:CLSA_RS19210
uniprot id: U5MWJ7
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

1345695:CLSA RS12780
gene id: 1345695:CLSA_RS12780
uniprot id: U5MVF0
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS06085
gene id: 1345695:CLSA_RS06085
uniprot id: U5MRF1
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1345695:CLSA RS05300
gene id: 1345695:CLSA_RS05300
uniprot id: U5MQZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1345695:CLSA RS02680
gene id: 1345695:CLSA_RS02680
uniprot id: U5MLU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1345695:CLSA RS11620
gene id: 1345695:CLSA_RS11620
uniprot id: U5MSB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1345695:CLSA RS15290
gene id: 1345695:CLSA_RS15290
uniprot id: U5MU84
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1345695:CLSA RS11575
gene id: 1345695:CLSA_RS11575
uniprot id: U5MRG6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS00395
gene id: 1345695:CLSA_RS00395
uniprot id: U5MKT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1345695:CLSA RS11775
gene id: 1345695:CLSA_RS11775
uniprot id: U5MS56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1345695:CLSA RS10205
gene id: 1345695:CLSA_RS10205
uniprot id: U5MRF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1345695:CLSA RS04205
gene id: 1345695:CLSA_RS04205
uniprot id: U5MMU8
names: Similarity
messages: Belongs to the CdaR family.

1345695:CLSA RS07675
gene id: 1345695:CLSA_RS07675
uniprot id: U5MPR4
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1345695:CLSA RS11650
gene id: 1345695:CLSA_RS11650
uniprot id: U5MRJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS03435
gene id: 1345695:CLSA_RS03435
uniprot id: U5MQK4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS03155
gene id: 1345695:CLSA_RS03155
uniprot id: U5MPN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1345695:CLSA RS20910
gene id: 1345695:CLSA_RS20910
uniprot id: U5MXJ0
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1345695:CLSA RS10605
gene id: 1345695:CLSA_RS10605
uniprot id: U5MU23
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS16345
gene id: 1345695:CLSA_RS16345
uniprot id: U5MV18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS03500
gene id: 1345695:CLSA_RS03500
uniprot id: U5MPW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1345695:CLSA RS18825
gene id: 1345695:CLSA_RS18825
uniprot id: U5MZF8
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1345695:CLSA RS09255
gene id: 1345695:CLSA_RS09255
uniprot id: U5MQP9
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1345695:CLSA RS18320
gene id: 1345695:CLSA_RS18320
uniprot id: U5MVY7
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

1345695:CLSA RS05865
gene id: 1345695:CLSA_RS05865
uniprot id: U5MRA3
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS09665
gene id: 1345695:CLSA_RS09665
uniprot id: U5MQW8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS04960
gene id: 1345695:CLSA_RS04960
uniprot id: U5MQT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1345695:CLSA RS06665
gene id: 1345695:CLSA_RS06665
uniprot id: U5MSG9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS20780
gene id: 1345695:CLSA_RS20780
uniprot id: U5MXG3
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS11600
gene id: 1345695:CLSA_RS11600
uniprot id: U5MRI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1345695:CLSA RS21250
gene id: 1345695:CLSA_RS21250
uniprot id: U5MXS3
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS13080
gene id: 1345695:CLSA_RS13080
uniprot id: U5MT21
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1345695:CLSA RS17500
gene id: 1345695:CLSA_RS17500
uniprot id: U5MVI2
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS12410
gene id: 1345695:CLSA_RS12410
uniprot id: U5MSQ0
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1345695:CLSA RS04700
gene id: 1345695:CLSA_RS04700
uniprot id: U5MMG4
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS09165
gene id: 1345695:CLSA_RS09165
uniprot id: U5MQU1
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1345695:CLSA RS11870
gene id: 1345695:CLSA_RS11870
uniprot id: U5MRN6
names: Similarity
messages: Belongs to the UPF0045 family.

1345695:CLSA RS04950
gene id: 1345695:CLSA_RS04950
uniprot id: U5MMK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1345695:CLSA RS15695
gene id: 1345695:CLSA_RS15695
uniprot id: U5MUM7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1345695:CLSA RS03310
gene id: 1345695:CLSA_RS03310
uniprot id: U5MMD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1345695:CLSA RS08795
gene id: 1345695:CLSA_RS08795
uniprot id: U5MQD0
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS00935
gene id: 1345695:CLSA_RS00935
uniprot id: U5MKA0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1345695:CLSA RS21825
gene id: 1345695:CLSA_RS21825
uniprot id: U5N0M7
names: Similarity
messages: Belongs to the ParB family.

1345695:CLSA RS03535
gene id: 1345695:CLSA_RS03535
uniprot id: U5MMI2
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1345695:CLSA RS13225
gene id: 1345695:CLSA_RS13225
uniprot id: U5MW83
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1345695:CLSA RS04140
gene id: 1345695:CLSA_RS04140
uniprot id: U5MR00
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1345695:CLSA RS14750
gene id: 1345695:CLSA_RS14750
uniprot id: U5MWN2
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS00255
gene id: 1345695:CLSA_RS00255
uniprot id: U5MKI7
names: Similarity
messages: Belongs to the peptidase S8 family.

1345695:CLSA RS10850
gene id: 1345695:CLSA_RS10850
uniprot id: U5MQY7
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1345695:CLSA RS13290
gene id: 1345695:CLSA_RS13290
uniprot id: U5MSD7
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1345695:CLSA RS02360
gene id: 1345695:CLSA_RS02360
uniprot id: U5MLW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1345695:CLSA RS00785
gene id: 1345695:CLSA_RS00785
uniprot id: U5MKS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS07185
gene id: 1345695:CLSA_RS07185
uniprot id: U5MNX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS13375
gene id: 1345695:CLSA_RS13375
uniprot id: U5MT15
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.

1345695:CLSA RS21755
gene id: 1345695:CLSA_RS21755
uniprot id: U5N129
names: Similarity
messages: Belongs to the peptidase S16 family.

1345695:CLSA RS16705
gene id: 1345695:CLSA_RS16705
uniprot id: U5MV99
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

1345695:CLSA RS03005
gene id: 1345695:CLSA_RS03005
uniprot id: U5MQC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1345695:CLSA RS15555
gene id: 1345695:CLSA_RS15555
uniprot id: U5MX53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the precorrin methyltransferase family.
messages: Homodimer.
messages: Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway.

1345695:CLSA RS01305
gene id: 1345695:CLSA_RS01305
uniprot id: U5MLA5
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
messages: In the N-terminal section; belongs to the DHNA family.

1345695:CLSA RS11200
gene id: 1345695:CLSA_RS11200
uniprot id: U5MRQ4
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1345695:CLSA RS03795
gene id: 1345695:CLSA_RS03795
uniprot id: U5MQS9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

1345695:CLSA RS21065
gene id: 1345695:CLSA_RS21065
uniprot id: U5MWZ7
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1345695:CLSA RS21020
gene id: 1345695:CLSA_RS21020
uniprot id: U5MWZ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS10090
gene id: 1345695:CLSA_RS10090
uniprot id: U5MTT0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS21490
gene id: 1345695:CLSA_RS21490
uniprot id: U5MY03
names: Similarity
messages: Belongs to the P(II) protein family.

1345695:CLSA RS20710
gene id: 1345695:CLSA_RS20710
uniprot id: U5MXE6
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS16095
gene id: 1345695:CLSA_RS16095
uniprot id: U5MUU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

1345695:CLSA RS11750
gene id: 1345695:CLSA_RS11750
uniprot id: U5MS51
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1345695:CLSA RS00965
gene id: 1345695:CLSA_RS00965
uniprot id: U5MKV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1345695:CLSA RS00740
gene id: 1345695:CLSA_RS00740
uniprot id: U5ML00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1345695:CLSA RS12880
gene id: 1345695:CLSA_RS12880
uniprot id: U5MW21
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1345695:CLSA RS01905
gene id: 1345695:CLSA_RS01905
uniprot id: U5MLI5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1345695:CLSA RS09875
gene id: 1345695:CLSA_RS09875
uniprot id: U5MR94
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1345695:CLSA RS15885
gene id: 1345695:CLSA_RS15885
uniprot id: U5MXB9
names: Similarity
messages: Belongs to the hemerythrin family.

1345695:CLSA RS07900
gene id: 1345695:CLSA_RS07900
uniprot id: U5MT42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1345695:CLSA RS20520
gene id: 1345695:CLSA_RS20520
uniprot id: U5MXA1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1345695:CLSA RS17240
gene id: 1345695:CLSA_RS17240
uniprot id: U5MYJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

1345695:CLSA RS14785
gene id: 1345695:CLSA_RS14785
uniprot id: U5MU44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane

1345695:CLSA RS03180
gene id: 1345695:CLSA_RS03180
uniprot id: U5MPP0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1345695:CLSA RS17675
gene id: 1345695:CLSA_RS17675
uniprot id: U5MVS3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

1345695:CLSA RS09695
gene id: 1345695:CLSA_RS09695
uniprot id: U5MU88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1345695:CLSA RS19680
gene id: 1345695:CLSA_RS19680
uniprot id: U5MZW1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS11225
gene id: 1345695:CLSA_RS11225
uniprot id: U5MRQ8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS05905
gene id: 1345695:CLSA_RS05905
uniprot id: U5MN27
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1345695:CLSA RS12835
gene id: 1345695:CLSA_RS12835
uniprot id: U5MW11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1345695:CLSA RS19860
gene id: 1345695:CLSA_RS19860
uniprot id: U5MZZ1
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1345695:CLSA RS07015
gene id: 1345695:CLSA_RS07015
uniprot id: U5MS28
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1345695:CLSA RS01345
gene id: 1345695:CLSA_RS01345
uniprot id: U5ML35
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1345695:CLSA RS00260
gene id: 1345695:CLSA_RS00260
uniprot id: U5MN62
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1345695:CLSA RS06040
gene id: 1345695:CLSA_RS06040
uniprot id: U5MS17
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1345695:CLSA RS19365
gene id: 1345695:CLSA_RS19365
uniprot id: U5MZQ5
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS08915
gene id: 1345695:CLSA_RS08915
uniprot id: U5MQF3
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1345695:CLSA RS12505
gene id: 1345695:CLSA_RS12505
uniprot id: U5MSR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

1345695:CLSA RS18035
gene id: 1345695:CLSA_RS18035
uniprot id: U5MYY1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1345695:CLSA RS01055
gene id: 1345695:CLSA_RS01055
uniprot id: U5MKC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1345695:CLSA RS01785
gene id: 1345695:CLSA_RS01785
uniprot id: U5MP43
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1345695:CLSA RS19065
gene id: 1345695:CLSA_RS19065
uniprot id: U5MZ61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1345695:CLSA RS06285
gene id: 1345695:CLSA_RS06285
uniprot id: U5MRJ1
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

1345695:CLSA RS06055
gene id: 1345695:CLSA_RS06055
uniprot id: U5MNS3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS13835
gene id: 1345695:CLSA_RS13835
uniprot id: U5MW23
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1345695:CLSA RS08600
gene id: 1345695:CLSA_RS08600
uniprot id: U5MPM2
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1345695:CLSA RS10855
gene id: 1345695:CLSA_RS10855
uniprot id: U5MRI2
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1345695:CLSA RS07010
gene id: 1345695:CLSA_RS07010
uniprot id: U5MPE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1345695:CLSA RS11970
gene id: 1345695:CLSA_RS11970
uniprot id: U5MS87
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS06590
gene id: 1345695:CLSA_RS06590
uniprot id: U5MSC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1345695:CLSA RS07535
gene id: 1345695:CLSA_RS07535
uniprot id: U5MSX6
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1345695:CLSA RS16945
gene id: 1345695:CLSA_RS16945
uniprot id: U5MYF2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1345695:CLSA RS18600
gene id: 1345695:CLSA_RS18600
uniprot id: U5MVK6
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS21570
gene id: 1345695:CLSA_RS21570
uniprot id: U5N0Y9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1345695:CLSA RS03545
gene id: 1345695:CLSA_RS03545
uniprot id: U5MMB6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS18845
gene id: 1345695:CLSA_RS18845
uniprot id: U5MZ29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1345695:CLSA RS13870
gene id: 1345695:CLSA_RS13870
uniprot id: U5MTH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1345695:CLSA RS13655
gene id: 1345695:CLSA_RS13655
uniprot id: U5MT79
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1345695:CLSA RS14600
gene id: 1345695:CLSA_RS14600
uniprot id: U5MX46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1345695:CLSA RS03610
gene id: 1345695:CLSA_RS03610
uniprot id: U5MMJ6
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1345695:CLSA RS18020
gene id: 1345695:CLSA_RS18020
uniprot id: U5MVT0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1345695:CLSA RS06445
gene id: 1345695:CLSA_RS06445
uniprot id: U5MP67
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1345695:CLSA RS08975
gene id: 1345695:CLSA_RS08975
uniprot id: U5MQN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1345695:CLSA RS15705
gene id: 1345695:CLSA_RS15705
uniprot id: U5MUG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1345695:CLSA RS06075
gene id: 1345695:CLSA_RS06075
uniprot id: U5MN64
names: Function
names: Similarity
messages: Belongs to the PyrI family.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

1345695:CLSA RS13210
gene id: 1345695:CLSA_RS13210
uniprot id: U5MSC0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1345695:CLSA RS19275
gene id: 1345695:CLSA_RS19275
uniprot id: U5MWR5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1345695:CLSA RS06095
gene id: 1345695:CLSA_RS06095
uniprot id: U5MNZ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

1345695:CLSA RS05285
gene id: 1345695:CLSA_RS05285
uniprot id: U5MNK2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1345695:CLSA RS02070
gene id: 1345695:CLSA_RS02070
uniprot id: U5ML02
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS03445
gene id: 1345695:CLSA_RS03445
uniprot id: U5MLN3
names: Similarity
messages: Belongs to the FBPase class 3 family.

1345695:CLSA RS19570
gene id: 1345695:CLSA_RS19570
uniprot id: U5MWR1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS19495
gene id: 1345695:CLSA_RS19495
uniprot id: U5MWP9
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1345695:CLSA RS08470
gene id: 1345695:CLSA_RS08470
uniprot id: U5MTF0
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1345695:CLSA RS01810
gene id: 1345695:CLSA_RS01810
uniprot id: U5MP48
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS04870
gene id: 1345695:CLSA_RS04870
uniprot id: U5MNC9
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS03425
gene id: 1345695:CLSA_RS03425
uniprot id: U5MM87
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1345695:CLSA RS18770
gene id: 1345695:CLSA_RS18770
uniprot id: U5MW82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1345695:CLSA RS06140
gene id: 1345695:CLSA_RS06140
uniprot id: U5MS38
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS02720
gene id: 1345695:CLSA_RS02720
uniprot id: U5MM27
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1345695:CLSA RS18235
gene id: 1345695:CLSA_RS18235
uniprot id: U5MZ10
names: Subcellular Location Annotation
messages: Cytoplasm

1345695:CLSA RS05485
gene id: 1345695:CLSA_RS05485
uniprot id: U5MR27
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1345695:CLSA RS14805
gene id: 1345695:CLSA_RS14805
uniprot id: U5MX76
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1345695:CLSA RS06110
gene id: 1345695:CLSA_RS06110
uniprot id: U5MRF6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

1345695:CLSA RS19840
gene id: 1345695:CLSA_RS19840
uniprot id: U5MX22
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1345695:CLSA RS05190
gene id: 1345695:CLSA_RS05190
uniprot id: U5MNI7
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

1345695:CLSA RS21275
gene id: 1345695:CLSA_RS21275
uniprot id: U5N0P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1345695:CLSA RS05520
gene id: 1345695:CLSA_RS05520
uniprot id: U5MNN8
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1345695:CLSA RS09535
gene id: 1345695:CLSA_RS09535
uniprot id: U5MR31
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1345695:CLSA RS02965
gene id: 1345695:CLSA_RS02965
uniprot id: U5MLD5
names: Similarity
messages: Belongs to the pyruvate kinase family.

1345695:CLSA RS09020
gene id: 1345695:CLSA_RS09020
uniprot id: U5MTR3
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

1345695:CLSA RS12115
gene id: 1345695:CLSA_RS12115
uniprot id: U5MV17
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1345695:CLSA RS14865
gene id: 1345695:CLSA_RS14865
uniprot id: U5MTZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1345695:CLSA RS03675
gene id: 1345695:CLSA_RS03675
uniprot id: U5MQ00
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS18445
gene id: 1345695:CLSA_RS18445
uniprot id: U5MW13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1345695:CLSA RS10980
gene id: 1345695:CLSA_RS10980
uniprot id: U5MRK6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1345695:CLSA RS10600
gene id: 1345695:CLSA_RS10600
uniprot id: U5MRD5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

1345695:CLSA RS01435
gene id: 1345695:CLSA_RS01435
uniprot id: U5MKK4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1345695:CLSA RS07345
gene id: 1345695:CLSA_RS07345
uniprot id: U5MNZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 4 family.
messages: Secreted

1345695:CLSA RS15335
gene id: 1345695:CLSA_RS15335
uniprot id: U5MTP1
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

1345695:CLSA RS08355
gene id: 1345695:CLSA_RS08355
uniprot id: U5MQ42
names: Similarity
messages: Belongs to the UPF0251 family.

1345695:CLSA RS11405
gene id: 1345695:CLSA_RS11405
uniprot id: U5MS23
names: Similarity
messages: Belongs to the TrpC family.

1345695:CLSA RS20330
gene id: 1345695:CLSA_RS20330
uniprot id: U5MZT1
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1345695:CLSA RS06390
gene id: 1345695:CLSA_RS06390
uniprot id: U5MS88
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1345695:CLSA RS21640
gene id: 1345695:CLSA_RS21640
uniprot id: U5MY21
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1345695:CLSA RS13885
gene id: 1345695:CLSA_RS13885
uniprot id: U5MW34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1345695:CLSA RS03025
gene id: 1345695:CLSA_RS03025
uniprot id: U5MM08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1345695:CLSA RS04615
gene id: 1345695:CLSA_RS04615
uniprot id: U5MQM1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1345695:CLSA RS18850
gene id: 1345695:CLSA_RS18850
uniprot id: U5MZG3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1345695:CLSA RS17910
gene id: 1345695:CLSA_RS17910
uniprot id: U5MV59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1345695:CLSA RS05840
gene id: 1345695:CLSA_RS05840
uniprot id: U5MR97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1345695:CLSA RS21060
gene id: 1345695:CLSA_RS21060
uniprot id: U5MXP5
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1345695:CLSA RS11265
gene id: 1345695:CLSA_RS11265
uniprot id: U5MR67
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS16085
gene id: 1345695:CLSA_RS16085
uniprot id: U5MXG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS12090
gene id: 1345695:CLSA_RS12090
uniprot id: U5MRS7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1345695:CLSA RS11315
gene id: 1345695:CLSA_RS11315
uniprot id: U5MR78
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS19785
gene id: 1345695:CLSA_RS19785
uniprot id: U5MZH0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1345695:CLSA RS13760
gene id: 1345695:CLSA_RS13760
uniprot id: U5MW07
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS08075
gene id: 1345695:CLSA_RS08075
uniprot id: U5MPC5
names: Similarity
messages: Belongs to the tannase family.

1345695:CLSA RS08560
gene id: 1345695:CLSA_RS08560
uniprot id: U5MSW0
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS05125
gene id: 1345695:CLSA_RS05125
uniprot id: U5MN97
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS08590
gene id: 1345695:CLSA_RS08590
uniprot id: U5MTH4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DbpA subfamily.
messages: Contains an N-terminal domain that binds non-specifically to RNA and a C-terminal domain that binds specifically and tightly to hairpin 92 of 23S rRNA.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes.

1345695:CLSA RS00885
gene id: 1345695:CLSA_RS00885
uniprot id: U5MKU1
names: Similarity
messages: Belongs to the ycf81 family.

1345695:CLSA RS15160
gene id: 1345695:CLSA_RS15160
uniprot id: U5MWW4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS05990
gene id: 1345695:CLSA_RS05990
uniprot id: U5MRD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1345695:CLSA RS03205
gene id: 1345695:CLSA_RS03205
uniprot id: U5MPP5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1345695:CLSA RS21120
gene id: 1345695:CLSA_RS21120
uniprot id: U5N070
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1345695:CLSA RS05575
gene id: 1345695:CLSA_RS05575
uniprot id: U5MMW4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1345695:CLSA RS02375
gene id: 1345695:CLSA_RS02375
uniprot id: U5MPB6
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

1345695:CLSA RS01005
gene id: 1345695:CLSA_RS01005
uniprot id: U5ML43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1345695:CLSA RS20805
gene id: 1345695:CLSA_RS20805
uniprot id: U5N031
names: Similarity
messages: Belongs to the DltD family.

1345695:CLSA RS02165
gene id: 1345695:CLSA_RS02165
uniprot id: U5MP88
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1345695:CLSA RS07330
gene id: 1345695:CLSA_RS07330
uniprot id: U5MS82
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1345695:CLSA RS05920
gene id: 1345695:CLSA_RS05920
uniprot id: U5MRZ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Involved in the cleavage of the C1-C2 bond of 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy-glucuronate (5DG).

1345695:CLSA RS08740
gene id: 1345695:CLSA_RS08740
uniprot id: U5MQI6
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

1345695:CLSA RS07720
gene id: 1345695:CLSA_RS07720
uniprot id: U5MP61
names: Similarity
messages: Belongs to the NAPRTase family.

1345695:CLSA RS02815
gene id: 1345695:CLSA_RS02815
uniprot id: U5MPI2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS19870
gene id: 1345695:CLSA_RS19870
uniprot id: U5MWC0
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1345695:CLSA RS05235
gene id: 1345695:CLSA_RS05235
uniprot id: U5MRM8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1345695:CLSA RS16105
gene id: 1345695:CLSA_RS16105
uniprot id: U5MU48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

1345695:CLSA RS19115
gene id: 1345695:CLSA_RS19115
uniprot id: U5MZ69
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

1345695:CLSA RS02415
gene id: 1345695:CLSA_RS02415
uniprot id: U5ML52
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS21295
gene id: 1345695:CLSA_RS21295
uniprot id: U5N0R8
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS15830
gene id: 1345695:CLSA_RS15830
uniprot id: U5MUI6
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

1345695:CLSA RS20015
gene id: 1345695:CLSA_RS20015
uniprot id: U5MZL9
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS20635
gene id: 1345695:CLSA_RS20635
uniprot id: U5MWR3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1345695:CLSA RS19670
gene id: 1345695:CLSA_RS19670
uniprot id: U5MWS8
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.

1345695:CLSA RS07505
gene id: 1345695:CLSA_RS07505
uniprot id: U5MSB3
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

1345695:CLSA RS22150
gene id: 1345695:CLSA_RS22150
uniprot id: U5MTR9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1345695:CLSA RS13255
gene id: 1345695:CLSA_RS13255
uniprot id: U5MW86
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1345695:CLSA RS19765
gene id: 1345695:CLSA_RS19765
uniprot id: U5MZX4
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1345695:CLSA RS03035
gene id: 1345695:CLSA_RS03035
uniprot id: U5MQC5
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1345695:CLSA RS09475
gene id: 1345695:CLSA_RS09475
uniprot id: U5MR18
names: Similarity
messages: Belongs to the UxaA family.

1345695:CLSA RS15000
gene id: 1345695:CLSA_RS15000
uniprot id: U5MU90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1345695:CLSA RS12050
gene id: 1345695:CLSA_RS12050
uniprot id: U5MV05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1345695:CLSA RS04975
gene id: 1345695:CLSA_RS04975
uniprot id: U5MML1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

1345695:CLSA RS00995
gene id: 1345695:CLSA_RS00995
uniprot id: U5MNI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1345695:CLSA RS00870
gene id: 1345695:CLSA_RS00870
uniprot id: U5MP59
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.

1345695:CLSA RS04690
gene id: 1345695:CLSA_RS04690
uniprot id: U5MRD4
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1345695:CLSA RS18585
gene id: 1345695:CLSA_RS18585
uniprot id: U5MYU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

1345695:CLSA RS18175
gene id: 1345695:CLSA_RS18175
uniprot id: U5MVV8
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS12955
gene id: 1345695:CLSA_RS12955
uniprot id: U5MSZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1345695:CLSA RS15530
gene id: 1345695:CLSA_RS15530
uniprot id: U5MX49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1345695:CLSA RS01580
gene id: 1345695:CLSA_RS01580
uniprot id: U5MP04
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS01750
gene id: 1345695:CLSA_RS01750
uniprot id: U5MKW2
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1345695:CLSA RS15380
gene id: 1345695:CLSA_RS15380
uniprot id: U5MXI7
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS01020
gene id: 1345695:CLSA_RS01020
uniprot id: U5MNJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1345695:CLSA RS18505
gene id: 1345695:CLSA_RS18505
uniprot id: U5MW85
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

1345695:CLSA RS11795
gene id: 1345695:CLSA_RS11795
uniprot id: U5MRM4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1345695:CLSA RS01205
gene id: 1345695:CLSA_RS01205
uniprot id: U5ML85
names: Similarity
messages: Belongs to the class-I fumarase family.

1345695:CLSA RS14690
gene id: 1345695:CLSA_RS14690
uniprot id: U5MTW5
names: Similarity
messages: Belongs to the peptidase M18 family.

1345695:CLSA RS03505
gene id: 1345695:CLSA_RS03505
uniprot id: U5MQL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1345695:CLSA RS20725
gene id: 1345695:CLSA_RS20725
uniprot id: U5MXJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

1345695:CLSA RS15550
gene id: 1345695:CLSA_RS15550
uniprot id: U5MUD3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1345695:CLSA RS00735
gene id: 1345695:CLSA_RS00735
uniprot id: U5MP42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1345695:CLSA RS13745
gene id: 1345695:CLSA_RS13745
uniprot id: U5MTF1
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1345695:CLSA RS00020
gene id: 1345695:CLSA_RS00020
uniprot id: U5MNT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1345695:CLSA RS09555
gene id: 1345695:CLSA_RS09555
uniprot id: U5MU63
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS15280
gene id: 1345695:CLSA_RS15280
uniprot id: U5MUE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1345695:CLSA RS05555
gene id: 1345695:CLSA_RS05555
uniprot id: U5MNH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1345695:CLSA RS15970
gene id: 1345695:CLSA_RS15970
uniprot id: U5MXT3
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS13815
gene id: 1345695:CLSA_RS13815
uniprot id: U5MWJ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS09965
gene id: 1345695:CLSA_RS09965
uniprot id: U5MTQ6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS13275
gene id: 1345695:CLSA_RS13275
uniprot id: U5MVQ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1345695:CLSA RS06890
gene id: 1345695:CLSA_RS06890
uniprot id: U5MSN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.

1345695:CLSA RS00930
gene id: 1345695:CLSA_RS00930
uniprot id: U5MNI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1345695:CLSA RS04660
gene id: 1345695:CLSA_RS04660
uniprot id: U5MQM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS00975
gene id: 1345695:CLSA_RS00975
uniprot id: U5MP76
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1345695:CLSA RS16510
gene id: 1345695:CLSA_RS16510
uniprot id: U5MV12
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1345695:CLSA RS08500
gene id: 1345695:CLSA_RS08500
uniprot id: U5MTF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS05110
gene id: 1345695:CLSA_RS05110
uniprot id: U5MRK4
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.

1345695:CLSA RS11930
gene id: 1345695:CLSA_RS11930
uniprot id: U5MVJ7
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS18915
gene id: 1345695:CLSA_RS18915
uniprot id: U5MWE6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1345695:CLSA RS06675
gene id: 1345695:CLSA_RS06675
uniprot id: U5MNK9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1345695:CLSA RS01240
gene id: 1345695:CLSA_RS01240
uniprot id: U5ML17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1345695:CLSA RS02875
gene id: 1345695:CLSA_RS02875
uniprot id: U5MM52
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

1345695:CLSA RS07430
gene id: 1345695:CLSA_RS07430
uniprot id: U5MS99
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1345695:CLSA RS02410
gene id: 1345695:CLSA_RS02410
uniprot id: U5MLX1
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS06730
gene id: 1345695:CLSA_RS06730
uniprot id: U5MP97
names: Similarity
messages: Belongs to the asp23 family.

1345695:CLSA RS15055
gene id: 1345695:CLSA_RS15055
uniprot id: U5MTI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1345695:CLSA RS03315
gene id: 1345695:CLSA_RS03315
uniprot id: U5MLK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS08410
gene id: 1345695:CLSA_RS08410
uniprot id: U5MSS9
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Dimer of large and small chains.

1345695:CLSA RS16065
gene id: 1345695:CLSA_RS16065
uniprot id: U5MXV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1345695:CLSA RS21765
gene id: 1345695:CLSA_RS21765
uniprot id: U5MXF6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

1345695:CLSA RS19585
gene id: 1345695:CLSA_RS19585
uniprot id: U5MWX5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1345695:CLSA RS01165
gene id: 1345695:CLSA_RS01165
uniprot id: U5MNM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

1345695:CLSA RS15085
gene id: 1345695:CLSA_RS15085
uniprot id: U5MWV0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1345695:CLSA RS05545
gene id: 1345695:CLSA_RS05545
uniprot id: U5MNP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1345695:CLSA RS20400
gene id: 1345695:CLSA_RS20400
uniprot id: U5MZU6
names: Similarity
messages: Belongs to the CpsD/CapB family.

1345695:CLSA RS06290
gene id: 1345695:CLSA_RS06290
uniprot id: U5MS67
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS00210
gene id: 1345695:CLSA_RS00210
uniprot id: U5MKH7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1345695:CLSA RS19935
gene id: 1345695:CLSA_RS19935
uniprot id: U5N005
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS10460
gene id: 1345695:CLSA_RS10460
uniprot id: U5MUL6
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

1345695:CLSA RS02010
gene id: 1345695:CLSA_RS02010
uniprot id: U5MPW1
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1345695:CLSA RS01250
gene id: 1345695:CLSA_RS01250
uniprot id: U5MPC8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

1345695:CLSA RS11605
gene id: 1345695:CLSA_RS11605
uniprot id: U5MS22
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1345695:CLSA RS10370
gene id: 1345695:CLSA_RS10370
uniprot id: U5MTX8
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS13675
gene id: 1345695:CLSA_RS13675
uniprot id: U5MSL7
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1345695:CLSA RS02620
gene id: 1345695:CLSA_RS02620
uniprot id: U5MQ53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1345695:CLSA RS18155
gene id: 1345695:CLSA_RS18155
uniprot id: U5MYK9
names: Similarity
messages: Belongs to the bacteriocin class IIA/YGNGV family.

1345695:CLSA RS12235
gene id: 1345695:CLSA_RS12235
uniprot id: U5MVQ4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1345695:CLSA RS19425
gene id: 1345695:CLSA_RS19425
uniprot id: U5MWN7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1345695:CLSA RS06165
gene id: 1345695:CLSA_RS06165
uniprot id: U5MS43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1345695:CLSA RS11920
gene id: 1345695:CLSA_RS11920
uniprot id: U5MS79
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1345695:CLSA RS05320
gene id: 1345695:CLSA_RS05320
uniprot id: U5MND2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1345695:CLSA RS01685
gene id: 1345695:CLSA_RS01685
uniprot id: U5MP26
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS06410
gene id: 1345695:CLSA_RS06410
uniprot id: U5MRM1
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1345695:CLSA RS06415
gene id: 1345695:CLSA_RS06415
uniprot id: U5MS91
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1345695:CLSA RS05730
gene id: 1345695:CLSA_RS05730
uniprot id: U5MNK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1345695:CLSA RS16145
gene id: 1345695:CLSA_RS16145
uniprot id: U5MXH7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1345695:CLSA RS19295
gene id: 1345695:CLSA_RS19295
uniprot id: U5MZP3
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1345695:CLSA RS01265
gene id: 1345695:CLSA_RS01265
uniprot id: U5ML21
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1345695:CLSA RS17820
gene id: 1345695:CLSA_RS17820
uniprot id: U5MYE6
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1345695:CLSA RS20800
gene id: 1345695:CLSA_RS20800
uniprot id: U5MWU9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily.
messages: Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS18660
gene id: 1345695:CLSA_RS18660
uniprot id: U5MYV5
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1345695:CLSA RS19435
gene id: 1345695:CLSA_RS19435
uniprot id: U5MZR9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1345695:CLSA RS05280
gene id: 1345695:CLSA_RS05280
uniprot id: U5MRN7
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1345695:CLSA RS09520
gene id: 1345695:CLSA_RS09520
uniprot id: U5MU54
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS01070
gene id: 1345695:CLSA_RS01070
uniprot id: U5MP94
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1345695:CLSA RS03105
gene id: 1345695:CLSA_RS03105
uniprot id: U5MQD7
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS18890
gene id: 1345695:CLSA_RS18890
uniprot id: U5MWE3
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1345695:CLSA RS06830
gene id: 1345695:CLSA_RS06830
uniprot id: U5MPB8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1345695:CLSA RS07670
gene id: 1345695:CLSA_RS07670
uniprot id: U5MP54
names: Similarity
messages: Belongs to the EamA transporter family.

1345695:CLSA RS05450
gene id: 1345695:CLSA_RS05450
uniprot id: U5MMU1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS12245
gene id: 1345695:CLSA_RS12245
uniprot id: U5MSD4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1345695:CLSA RS19475
gene id: 1345695:CLSA_RS19475
uniprot id: U5MWP5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1345695:CLSA RS18220
gene id: 1345695:CLSA_RS18220
uniprot id: U5MVB6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1345695:CLSA RS00540
gene id: 1345695:CLSA_RS00540
uniprot id: U5MNB1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS15740
gene id: 1345695:CLSA_RS15740
uniprot id: U5MXP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

1345695:CLSA RS12725
gene id: 1345695:CLSA_RS12725
uniprot id: U5MSM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1345695:CLSA RS09625
gene id: 1345695:CLSA_RS09625
uniprot id: U5MTK0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1345695:CLSA RS01875
gene id: 1345695:CLSA_RS01875
uniprot id: U5MKY5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1345695:CLSA RS17420
gene id: 1345695:CLSA_RS17420
uniprot id: U5MVM7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1345695:CLSA RS11410
gene id: 1345695:CLSA_RS11410
uniprot id: U5MRA5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS21495
gene id: 1345695:CLSA_RS21495
uniprot id: U5MXC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS12225
gene id: 1345695:CLSA_RS12225
uniprot id: U5MSD0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1345695:CLSA RS10680
gene id: 1345695:CLSA_RS10680
uniprot id: U5MRN5
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1345695:CLSA RS15880
gene id: 1345695:CLSA_RS15880
uniprot id: U5MUJ6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1345695:CLSA RS19150
gene id: 1345695:CLSA_RS19150
uniprot id: U5MWP6
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1345695:CLSA RS03645
gene id: 1345695:CLSA_RS03645
uniprot id: U5MME0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS09180
gene id: 1345695:CLSA_RS09180
uniprot id: U5MTB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS13910
gene id: 1345695:CLSA_RS13910
uniprot id: U5MWL4
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1345695:CLSA RS05960
gene id: 1345695:CLSA_RS05960
uniprot id: U5MNQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1345695:CLSA RS11655
gene id: 1345695:CLSA_RS11655
uniprot id: U5MS30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS15835
gene id: 1345695:CLSA_RS15835
uniprot id: U5MXA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS08215
gene id: 1345695:CLSA_RS08215
uniprot id: U5MSP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1345695:CLSA RS13220
gene id: 1345695:CLSA_RS13220
uniprot id: U5MVP3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1345695:CLSA RS13280
gene id: 1345695:CLSA_RS13280
uniprot id: U5MW89
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1345695:CLSA RS15500
gene id: 1345695:CLSA_RS15500
uniprot id: U5MUC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1345695:CLSA RS21865
gene id: 1345695:CLSA_RS21865
uniprot id: U5MXH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1345695:CLSA RS20385
gene id: 1345695:CLSA_RS20385
uniprot id: U5N082
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1345695:CLSA RS00200
gene id: 1345695:CLSA_RS00200
uniprot id: U5MKQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1345695:CLSA RS19270
gene id: 1345695:CLSA_RS19270
uniprot id: U5MZN9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1345695:CLSA RS15985
gene id: 1345695:CLSA_RS15985
uniprot id: U5MUM0
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS08690
gene id: 1345695:CLSA_RS08690
uniprot id: U5MQH6
names: Similarity
messages: Belongs to the KdgT transporter family.

1345695:CLSA RS00460
gene id: 1345695:CLSA_RS00460
uniprot id: U5MKM9
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1345695:CLSA RS18935
gene id: 1345695:CLSA_RS18935
uniprot id: U5MVW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1345695:CLSA RS10955
gene id: 1345695:CLSA_RS10955
uniprot id: U5MRT9
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1345695:CLSA RS03165
gene id: 1345695:CLSA_RS03165
uniprot id: U5MMA3
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1345695:CLSA RS13140
gene id: 1345695:CLSA_RS13140
uniprot id: U5MSX5
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1345695:CLSA RS06795
gene id: 1345695:CLSA_RS06795
uniprot id: U5MPI4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1345695:CLSA RS20075
gene id: 1345695:CLSA_RS20075
uniprot id: U5MWF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1345695:CLSA RS06620
gene id: 1345695:CLSA_RS06620
uniprot id: U5MPA6
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1345695:CLSA RS20820
gene id: 1345695:CLSA_RS20820
uniprot id: U5MWV5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1345695:CLSA RS10685
gene id: 1345695:CLSA_RS10685
uniprot id: U5MQU9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1345695:CLSA RS20980
gene id: 1345695:CLSA_RS20980
uniprot id: U5N058
names: Similarity
messages: Belongs to the peptidase C56 family.

1345695:CLSA RS00685
gene id: 1345695:CLSA_RS00685
uniprot id: U5MKR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1345695:CLSA RS13300
gene id: 1345695:CLSA_RS13300
uniprot id: U5MVQ8
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

1345695:CLSA RS00240
gene id: 1345695:CLSA_RS00240
uniprot id: U5MNW3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1345695:CLSA RS20575
gene id: 1345695:CLSA_RS20575
uniprot id: U5MUD2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1345695:CLSA RS00215
gene id: 1345695:CLSA_RS00215
uniprot id: U5MN50
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1345695:CLSA RS21005
gene id: 1345695:CLSA_RS21005
uniprot id: U5MXN9
names: Similarity
messages: Belongs to the peptidase A8 family.

1345695:CLSA RS11480
gene id: 1345695:CLSA_RS11480
uniprot id: U5MN47
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1345695:CLSA RS21045
gene id: 1345695:CLSA_RS21045
uniprot id: U5MXK6
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

1345695:CLSA RS20475
gene id: 1345695:CLSA_RS20475
uniprot id: U5MZW2
names: Similarity
messages: Belongs to the peptidase M18 family.

1345695:CLSA RS05665
gene id: 1345695:CLSA_RS05665
uniprot id: U5MRV3
names: Similarity
messages: Belongs to the glutamine synthetase family.

1345695:CLSA RS07350
gene id: 1345695:CLSA_RS07350
uniprot id: U5MPK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1345695:CLSA RS19665
gene id: 1345695:CLSA_RS19665
uniprot id: U5MW88
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1345695:CLSA RS09585
gene id: 1345695:CLSA_RS09585
uniprot id: U5MR39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1345695:CLSA RS12965
gene id: 1345695:CLSA_RS12965
uniprot id: U5MSU5
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1345695:CLSA RS10670
gene id: 1345695:CLSA_RS10670
uniprot id: U5MU39
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS21215
gene id: 1345695:CLSA_RS21215
uniprot id: U5N092
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS13725
gene id: 1345695:CLSA_RS13725
uniprot id: U5MSM9
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS10300
gene id: 1345695:CLSA_RS10300
uniprot id: U5MTW7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS22680
gene id: 1345695:CLSA_RS22680
uniprot id: U5MW67
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1345695:CLSA RS22090
gene id: 1345695:CLSA_RS22090
uniprot id: U5MUF4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS06840
gene id: 1345695:CLSA_RS06840
uniprot id: U5MSM2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1345695:CLSA RS11755
gene id: 1345695:CLSA_RS11755
uniprot id: U5MUV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
messages: Cytoplasm

1345695:CLSA RS20035
gene id: 1345695:CLSA_RS20035
uniprot id: U5MX05
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1345695:CLSA RS00510
gene id: 1345695:CLSA_RS00510
uniprot id: U5MKN9
names: Similarity
messages: Belongs to the peptidase M24B family.

1345695:CLSA RS05690
gene id: 1345695:CLSA_RS05690
uniprot id: U5MRV6
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1345695:CLSA RS20275
gene id: 1345695:CLSA_RS20275
uniprot id: U5MX52
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS06005
gene id: 1345695:CLSA_RS06005
uniprot id: U5MN51
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

1345695:CLSA RS12825
gene id: 1345695:CLSA_RS12825
uniprot id: U5MSR6
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1345695:CLSA RS15825
gene id: 1345695:CLSA_RS15825
uniprot id: U5MTY7
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

1345695:CLSA RS01535
gene id: 1345695:CLSA_RS01535
uniprot id: U5MPM1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1345695:CLSA RS07360
gene id: 1345695:CLSA_RS07360
uniprot id: U5MSU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1345695:CLSA RS19345
gene id: 1345695:CLSA_RS19345
uniprot id: U5MZQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1345695:CLSA RS01545
gene id: 1345695:CLSA_RS01545
uniprot id: U5MKQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1345695:CLSA RS13965
gene id: 1345695:CLSA_RS13965
uniprot id: U5MWM6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1345695:CLSA RS04810
gene id: 1345695:CLSA_RS04810
uniprot id: U5MN48
names: Similarity
messages: Belongs to the KdgT transporter family.

1345695:CLSA RS12490
gene id: 1345695:CLSA_RS12490
uniprot id: U5MSH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1345695:CLSA RS14735
gene id: 1345695:CLSA_RS14735
uniprot id: U5MU35
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

1345695:CLSA RS08280
gene id: 1345695:CLSA_RS08280
uniprot id: U5MPF6
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS19340
gene id: 1345695:CLSA_RS19340
uniprot id: U5MZA1
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

1345695:CLSA RS09860
gene id: 1345695:CLSA_RS09860
uniprot id: U5MR01
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS03250
gene id: 1345695:CLSA_RS03250
uniprot id: U5MM51
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

1345695:CLSA RS02275
gene id: 1345695:CLSA_RS02275
uniprot id: U5MP98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS02950
gene id: 1345695:CLSA_RS02950
uniprot id: U5MPK2
names: Similarity
messages: Belongs to the PspA/IM30 family.

1345695:CLSA RS15040
gene id: 1345695:CLSA_RS15040
uniprot id: U5MWU0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1345695:CLSA RS15120
gene id: 1345695:CLSA_RS15120
uniprot id: U5MUB4
names: Similarity
messages: Belongs to the threonine synthase family.

1345695:CLSA RS13600
gene id: 1345695:CLSA_RS13600
uniprot id: U5MWE7
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers).

1345695:CLSA RS13130
gene id: 1345695:CLSA_RS13130
uniprot id: U5MT32
names: Similarity
messages: Belongs to the YggT family.

1345695:CLSA RS10715
gene id: 1345695:CLSA_RS10715
uniprot id: U5MRF8
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS00410
gene id: 1345695:CLSA_RS00410
uniprot id: U5MN87
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1345695:CLSA RS16405
gene id: 1345695:CLSA_RS16405
uniprot id: U5MXR0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1345695:CLSA RS06680
gene id: 1345695:CLSA_RS06680
uniprot id: U5MP71
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1345695:CLSA RS01365
gene id: 1345695:CLSA_RS01365
uniprot id: U5MKI6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS01330
gene id: 1345695:CLSA_RS01330
uniprot id: U5MPE3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1345695:CLSA RS13580
gene id: 1345695:CLSA_RS13580
uniprot id: U5MTB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1345695:CLSA RS13170
gene id: 1345695:CLSA_RS13170
uniprot id: U5MVN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS14975
gene id: 1345695:CLSA_RS14975
uniprot id: U5MU86
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1345695:CLSA RS15755
gene id: 1345695:CLSA_RS15755
uniprot id: U5MUH0
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS06905
gene id: 1345695:CLSA_RS06905
uniprot id: U5MPC9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS18815
gene id: 1345695:CLSA_RS18815
uniprot id: U5MVU5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1345695:CLSA RS12590
gene id: 1345695:CLSA_RS12590
uniprot id: U5MVW1
names: Subcellular Location Annotation
messages: Cytoplasm

1345695:CLSA RS12910
gene id: 1345695:CLSA_RS12910
uniprot id: U5MS68
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS04595
gene id: 1345695:CLSA_RS04595
uniprot id: U5MRB7
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

1345695:CLSA RS20645
gene id: 1345695:CLSA_RS20645
uniprot id: U5MZZ6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS11490
gene id: 1345695:CLSA_RS11490
uniprot id: U5MUL9
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS10070
gene id: 1345695:CLSA_RS10070
uniprot id: U5MRD2
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1345695:CLSA RS07110
gene id: 1345695:CLSA_RS07110
uniprot id: U5MPG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1345695:CLSA RS14605
gene id: 1345695:CLSA_RS14605
uniprot id: U5MU12
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS03590
gene id: 1345695:CLSA_RS03590
uniprot id: U5MLR7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1345695:CLSA RS10765
gene id: 1345695:CLSA_RS10765
uniprot id: U5MRG5
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1345695:CLSA RS03490
gene id: 1345695:CLSA_RS03490
uniprot id: U5MLP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1345695:CLSA RS13695
gene id: 1345695:CLSA_RS13695
uniprot id: U5MTE2
names: Similarity
messages: Belongs to the asparagine synthetase family.

1345695:CLSA RS07100
gene id: 1345695:CLSA_RS07100
uniprot id: U5MPM9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1345695:CLSA RS15890
gene id: 1345695:CLSA_RS15890
uniprot id: U5MXS1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

1345695:CLSA RS21850
gene id: 1345695:CLSA_RS21850
uniprot id: U5N0N0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS06690
gene id: 1345695:CLSA_RS06690
uniprot id: U5MSJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1345695:CLSA RS05590
gene id: 1345695:CLSA_RS05590
uniprot id: U5MRU1
names: Similarity
messages: Belongs to the GSP E family.

1345695:CLSA RS01555
gene id: 1345695:CLSA_RS01555
uniprot id: U5MNZ7
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS09455
gene id: 1345695:CLSA_RS09455
uniprot id: U5MQ86
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1345695:CLSA RS03415
gene id: 1345695:CLSA_RS03415
uniprot id: U5MQK1
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1345695:CLSA RS00920
gene id: 1345695:CLSA_RS00920
uniprot id: U5MP66
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival.

1345695:CLSA RS05350
gene id: 1345695:CLSA_RS05350
uniprot id: U5MR06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

1345695:CLSA RS18740
gene id: 1345695:CLSA_RS18740
uniprot id: U5MWD0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1345695:CLSA RS10885
gene id: 1345695:CLSA_RS10885
uniprot id: U5MU87
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1345695:CLSA RS09460
gene id: 1345695:CLSA_RS09460
uniprot id: U5MQT3
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1345695:CLSA RS02440
gene id: 1345695:CLSA_RS02440
uniprot id: U5ML55
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1345695:CLSA RS08835
gene id: 1345695:CLSA_RS08835
uniprot id: U5MQK7
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS08545
gene id: 1345695:CLSA_RS08545
uniprot id: U5MSV5
names: Similarity
messages: Belongs to the EamA transporter family.

1345695:CLSA RS06205
gene id: 1345695:CLSA_RS06205
uniprot id: U5MNV6
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS01285
gene id: 1345695:CLSA_RS01285
uniprot id: U5MKG9
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1345695:CLSA RS01010
gene id: 1345695:CLSA_RS01010
uniprot id: U5MKB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1345695:CLSA RS14825
gene id: 1345695:CLSA_RS14825
uniprot id: U5MWP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1345695:CLSA RS00955
gene id: 1345695:CLSA_RS00955
uniprot id: U5ML32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1345695:CLSA RS11675
gene id: 1345695:CLSA_RS11675
uniprot id: U5MRK2
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1345695:CLSA RS17655
gene id: 1345695:CLSA_RS17655
uniprot id: U5MV16
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS00680
gene id: 1345695:CLSA_RS00680
uniprot id: U5MK56
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1345695:CLSA RS06160
gene id: 1345695:CLSA_RS06160
uniprot id: U5MRG7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1345695:CLSA RS12925
gene id: 1345695:CLSA_RS12925
uniprot id: U5MW31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1345695:CLSA RS15610
gene id: 1345695:CLSA_RS15610
uniprot id: U5MXN4
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

1345695:CLSA RS05660
gene id: 1345695:CLSA_RS05660
uniprot id: U5MR60
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1345695:CLSA RS03350
gene id: 1345695:CLSA_RS03350
uniprot id: U5MQI4
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1345695:CLSA RS20050
gene id: 1345695:CLSA_RS20050
uniprot id: U5MX61
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1345695:CLSA RS04745
gene id: 1345695:CLSA_RS04745
uniprot id: U5MN99
names: Similarity
messages: Belongs to the bacteriocin class IIA/YGNGV family.

1345695:CLSA RS08725
gene id: 1345695:CLSA_RS08725
uniprot id: U5MQB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1345695:CLSA RS01800
gene id: 1345695:CLSA_RS01800
uniprot id: U5MKX0
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1345695:CLSA RS05145
gene id: 1345695:CLSA_RS05145
uniprot id: U5MMP0
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS14125
gene id: 1345695:CLSA_RS14125
uniprot id: U5MWB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1345695:CLSA RS18620
gene id: 1345695:CLSA_RS18620
uniprot id: U5MWA4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1345695:CLSA RS01175
gene id: 1345695:CLSA_RS01175
uniprot id: U5ML79
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS06555
gene id: 1345695:CLSA_RS06555
uniprot id: U5MP22
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1345695:CLSA RS08805
gene id: 1345695:CLSA_RS08805
uniprot id: U5MTL7
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.

1345695:CLSA RS13230
gene id: 1345695:CLSA_RS13230
uniprot id: U5MT54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1345695:CLSA RS20220
gene id: 1345695:CLSA_RS20220
uniprot id: U5MX90
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1345695:CLSA RS03235
gene id: 1345695:CLSA_RS03235
uniprot id: U5MQG1
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

1345695:CLSA RS15030
gene id: 1345695:CLSA_RS15030
uniprot id: U5MTI4
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1345695:CLSA RS21270
gene id: 1345695:CLSA_RS21270
uniprot id: U5N0A2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1345695:CLSA RS18580
gene id: 1345695:CLSA_RS18580
uniprot id: U5MW47
names: Similarity
messages: Belongs to the ArsC family.

1345695:CLSA RS21285
gene id: 1345695:CLSA_RS21285
uniprot id: U5MXP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

1345695:CLSA RS03570
gene id: 1345695:CLSA_RS03570
uniprot id: U5MMC1
names: Similarity
messages: Belongs to the peptidase S8 family.

1345695:CLSA RS08700
gene id: 1345695:CLSA_RS08700
uniprot id: U5MQB3
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS17680
gene id: 1345695:CLSA_RS17680
uniprot id: U5MV21
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

1345695:CLSA RS01855
gene id: 1345695:CLSA_RS01855
uniprot id: U5MLH6
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1345695:CLSA RS01410
gene id: 1345695:CLSA_RS01410
uniprot id: U5MKJ7
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS20310
gene id: 1345695:CLSA_RS20310
uniprot id: U5N067
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1345695:CLSA RS04180
gene id: 1345695:CLSA_RS04180
uniprot id: U5MMS7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1345695:CLSA RS01150
gene id: 1345695:CLSA_RS01150
uniprot id: U5ML73
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1345695:CLSA RS20535
gene id: 1345695:CLSA_RS20535
uniprot id: U5MXF2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1345695:CLSA RS06190
gene id: 1345695:CLSA_RS06190
uniprot id: U5MS48
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

1345695:CLSA RS00405
gene id: 1345695:CLSA_RS00405
uniprot id: U5MKL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1345695:CLSA RS13880
gene id: 1345695:CLSA_RS13880
uniprot id: U5MTC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1345695:CLSA RS17920
gene id: 1345695:CLSA_RS17920
uniprot id: U5MYG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1345695:CLSA RS06875
gene id: 1345695:CLSA_RS06875
uniprot id: U5MNR9
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1345695:CLSA RS12905
gene id: 1345695:CLSA_RS12905
uniprot id: U5MSZ0
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1345695:CLSA RS13060
gene id: 1345695:CLSA_RS13060
uniprot id: U5MS94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1345695:CLSA RS20500
gene id: 1345695:CLSA_RS20500
uniprot id: U5MZW7
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS05070
gene id: 1345695:CLSA_RS05070
uniprot id: U5MMM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

1345695:CLSA RS00525
gene id: 1345695:CLSA_RS00525
uniprot id: U5MKW9
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

1345695:CLSA RS13445
gene id: 1345695:CLSA_RS13445
uniprot id: U5MVT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1345695:CLSA RS12740
gene id: 1345695:CLSA_RS12740
uniprot id: U5MSW3
names: Function
messages: May be involved in the biosynthesis of molybdopterin.

1345695:CLSA RS15385
gene id: 1345695:CLSA_RS15385
uniprot id: U5MUG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1345695:CLSA RS18685
gene id: 1345695:CLSA_RS18685
uniprot id: U5MYW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS06465
gene id: 1345695:CLSA_RS06465
uniprot id: U5MSA1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS10920
gene id: 1345695:CLSA_RS10920
uniprot id: U5MU92
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1345695:CLSA RS07045
gene id: 1345695:CLSA_RS07045
uniprot id: U5MSP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1345695:CLSA RS10320
gene id: 1345695:CLSA_RS10320
uniprot id: U5MR80
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1345695:CLSA RS09150
gene id: 1345695:CLSA_RS09150
uniprot id: U5MQJ4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1345695:CLSA RS19125
gene id: 1345695:CLSA_RS19125
uniprot id: U5MWP3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS03775
gene id: 1345695:CLSA_RS03775
uniprot id: U5MQS5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1345695:CLSA RS15190
gene id: 1345695:CLSA_RS15190
uniprot id: U5MXF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

1345695:CLSA RS06125
gene id: 1345695:CLSA_RS06125
uniprot id: U5MN75
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1345695:CLSA RS17690
gene id: 1345695:CLSA_RS17690
uniprot id: U5MYC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

1345695:CLSA RS19360
gene id: 1345695:CLSA_RS19360
uniprot id: U5MZA5
names: Similarity
messages: Belongs to the RNase H family.

1345695:CLSA RS12950
gene id: 1345695:CLSA_RS12950
uniprot id: U5MW36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1345695:CLSA RS03410
gene id: 1345695:CLSA_RS03410
uniprot id: U5MPU3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1345695:CLSA RS06025
gene id: 1345695:CLSA_RS06025
uniprot id: U5MNY6
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS02985
gene id: 1345695:CLSA_RS02985
uniprot id: U5MM70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1345695:CLSA RS10480
gene id: 1345695:CLSA_RS10480
uniprot id: U5MTZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS15910
gene id: 1345695:CLSA_RS15910
uniprot id: U5MXC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS06660
gene id: 1345695:CLSA_RS06660
uniprot id: U5MRU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1345695:CLSA RS04230
gene id: 1345695:CLSA_RS04230
uniprot id: U5MMV3
names: Similarity
messages: Belongs to the glycosyl hydrolase.

1345695:CLSA RS11835
gene id: 1345695:CLSA_RS11835
uniprot id: U5MVH5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS03510
gene id: 1345695:CLSA_RS03510
uniprot id: U5MMH7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS18065
gene id: 1345695:CLSA_RS18065
uniprot id: U5MYY5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS16140
gene id: 1345695:CLSA_RS16140
uniprot id: U5MUQ0
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1345695:CLSA RS01650
gene id: 1345695:CLSA_RS01650
uniprot id: U5MLL6
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS17270
gene id: 1345695:CLSA_RS17270
uniprot id: U5MVJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS00355
gene id: 1345695:CLSA_RS00355
uniprot id: U5MKK5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS02420
gene id: 1345695:CLSA_RS02420
uniprot id: U5MLQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

1345695:CLSA RS10000
gene id: 1345695:CLSA_RS10000
uniprot id: U5MQI2
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS06920
gene id: 1345695:CLSA_RS06920
uniprot id: U5MPK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1345695:CLSA RS07060
gene id: 1345695:CLSA_RS07060
uniprot id: U5MPF2
names: Similarity
messages: Belongs to the ribF family.

1345695:CLSA RS06835
gene id: 1345695:CLSA_RS06835
uniprot id: U5MRZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1345695:CLSA RS20790
gene id: 1345695:CLSA_RS20790
uniprot id: U5N0G5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-DCP.
messages: Belongs to the DltC family.
messages: Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
messages: Cytoplasm

1345695:CLSA RS17960
gene id: 1345695:CLSA_RS17960
uniprot id: U5MVX6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

1345695:CLSA RS07520
gene id: 1345695:CLSA_RS07520
uniprot id: U5MP28
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1345695:CLSA RS00990
gene id: 1345695:CLSA_RS00990
uniprot id: U5MKW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1345695:CLSA RS07020
gene id: 1345695:CLSA_RS07020
uniprot id: U5MSP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1345695:CLSA RS10725
gene id: 1345695:CLSA_RS10725
uniprot id: U5MUR4
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

1345695:CLSA RS06495
gene id: 1345695:CLSA_RS06495
uniprot id: U5MP78
names: Similarity
messages: Belongs to the UPF0473 family.

1345695:CLSA RS18375
gene id: 1345695:CLSA_RS18375
uniprot id: U5MVZ7
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS09105
gene id: 1345695:CLSA_RS09105
uniprot id: U5MT68
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1345695:CLSA RS09635
gene id: 1345695:CLSA_RS09635
uniprot id: U5MR46
names: Similarity
messages: Belongs to the glycosyl hydrolase 11 (cellulase G) family.

1345695:CLSA RS19815
gene id: 1345695:CLSA_RS19815
uniprot id: U5MZY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1345695:CLSA RS02300
gene id: 1345695:CLSA_RS02300
uniprot id: U5MPA2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1345695:CLSA RS15915
gene id: 1345695:CLSA_RS15915
uniprot id: U5MXS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1345695:CLSA RS14695
gene id: 1345695:CLSA_RS14695
uniprot id: U5MWM2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1345695:CLSA RS15200
gene id: 1345695:CLSA_RS15200
uniprot id: U5MTL4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1345695:CLSA RS08130
gene id: 1345695:CLSA_RS08130
uniprot id: U5MQ02
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

1345695:CLSA RS18400
gene id: 1345695:CLSA_RS18400
uniprot id: U5MW03
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS19675
gene id: 1345695:CLSA_RS19675
uniprot id: U5MZF1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1345695:CLSA RS12460
gene id: 1345695:CLSA_RS12460
uniprot id: U5MRY5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1345695:CLSA RS18060
gene id: 1345695:CLSA_RS18060
uniprot id: U5MYJ1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1345695:CLSA RS06640
gene id: 1345695:CLSA_RS06640
uniprot id: U5MSE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS02685
gene id: 1345695:CLSA_RS02685
uniprot id: U5MPF9
names: Similarity
messages: Belongs to the EamA transporter family.

1345695:CLSA RS20495
gene id: 1345695:CLSA_RS20495
uniprot id: U5MX95
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1345695:CLSA RS10950
gene id: 1345695:CLSA_RS10950
uniprot id: U5MUV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS01075
gene id: 1345695:CLSA_RS01075
uniprot id: U5ML58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1345695:CLSA RS17745
gene id: 1345695:CLSA_RS17745
uniprot id: U5MVN0
names: Similarity
messages: Belongs to the PRORSD1 family.

1345695:CLSA RS05225
gene id: 1345695:CLSA_RS05225
uniprot id: U5MNB4
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS18515
gene id: 1345695:CLSA_RS18515
uniprot id: U5MW28
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1345695:CLSA RS16735
gene id: 1345695:CLSA_RS16735
uniprot id: U5MUL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CitD family.
messages: Covalent carrier of the coenzyme of citrate lyase.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.

1345695:CLSA RS06750
gene id: 1345695:CLSA_RS06750
uniprot id: U5MNP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1345695:CLSA RS14585
gene id: 1345695:CLSA_RS14585
uniprot id: U5MTB3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1345695:CLSA RS07730
gene id: 1345695:CLSA_RS07730
uniprot id: U5MSF4
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1345695:CLSA RS20465
gene id: 1345695:CLSA_RS20465
uniprot id: U5MWN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1345695:CLSA RS01640
gene id: 1345695:CLSA_RS01640
uniprot id: U5MP16
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS10240
gene id: 1345695:CLSA_RS10240
uniprot id: U5MR66
names: Similarity
messages: Belongs to the EamA transporter family.

1345695:CLSA RS01360
gene id: 1345695:CLSA_RS01360
uniprot id: U5MLB6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1345695:CLSA RS05305
gene id: 1345695:CLSA_RS05305
uniprot id: U5MRP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1345695:CLSA RS12420
gene id: 1345695:CLSA_RS12420
uniprot id: U5MSG4
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1345695:CLSA RS20555
gene id: 1345695:CLSA_RS20555
uniprot id: U5N0B5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1345695:CLSA RS12380
gene id: 1345695:CLSA_RS12380
uniprot id: U5MSP7
names: Similarity
messages: Belongs to the glutamine synthetase family.

1345695:CLSA RS18705
gene id: 1345695:CLSA_RS18705
uniprot id: U5MYW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1345695:CLSA RS18635
gene id: 1345695:CLSA_RS18635
uniprot id: U5MYV0
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1345695:CLSA RS10930
gene id: 1345695:CLSA_RS10930
uniprot id: U5MRT5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1345695:CLSA RS03705
gene id: 1345695:CLSA_RS03705
uniprot id: U5MQQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1345695:CLSA RS06120
gene id: 1345695:CLSA_RS06120
uniprot id: U5MP06
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

1345695:CLSA RS09995
gene id: 1345695:CLSA_RS09995
uniprot id: U5MRB8
names: Subcellular Location Annotation
messages: Cytoplasm

1345695:CLSA RS15905
gene id: 1345695:CLSA_RS15905
uniprot id: U5MUK1
names: Similarity
messages: Belongs to the DtxR/MntR family.

1345695:CLSA RS12625
gene id: 1345695:CLSA_RS12625
uniprot id: U5MSK4
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1345695:CLSA RS11375
gene id: 1345695:CLSA_RS11375
uniprot id: U5MUI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1345695:CLSA RS09385
gene id: 1345695:CLSA_RS09385
uniprot id: U5MQS3
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1345695:CLSA RS18540
gene id: 1345695:CLSA_RS18540
uniprot id: U5MW35
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1345695:CLSA RS12540
gene id: 1345695:CLSA_RS12540
uniprot id: U5MVV3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1345695:CLSA RS11010
gene id: 1345695:CLSA_RS11010
uniprot id: U5MUB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

1345695:CLSA RS14880
gene id: 1345695:CLSA_RS14880
uniprot id: U5MU66
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS13365
gene id: 1345695:CLSA_RS13365
uniprot id: U5MT77
names: Similarity
messages: Belongs to the peptidase S66 family.

1345695:CLSA RS21150
gene id: 1345695:CLSA_RS21150
uniprot id: U5N0M3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1345695:CLSA RS12960
gene id: 1345695:CLSA_RS12960
uniprot id: U5MS76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1345695:CLSA RS04380
gene id: 1345695:CLSA_RS04380
uniprot id: U5MMB3
names: Cofactor
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN covalently per subunit.

1345695:CLSA RS00695
gene id: 1345695:CLSA_RS00695
uniprot id: U5MP36
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1345695:CLSA RS00485
gene id: 1345695:CLSA_RS00485
uniprot id: U5MKN5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1345695:CLSA RS17765
gene id: 1345695:CLSA_RS17765
uniprot id: U5MV32
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS05295
gene id: 1345695:CLSA_RS05295
uniprot id: U5MNC8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS05185
gene id: 1345695:CLSA_RS05185
uniprot id: U5MRL6
names: Similarity
messages: Belongs to the peptidase S16 family.

1345695:CLSA RS03255
gene id: 1345695:CLSA_RS03255
uniprot id: U5MQG5
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

1345695:CLSA RS01180
gene id: 1345695:CLSA_RS01180
uniprot id: U5MKE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1345695:CLSA RS16665
gene id: 1345695:CLSA_RS16665
uniprot id: U5MV35
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

1345695:CLSA RS07440
gene id: 1345695:CLSA_RS07440
uniprot id: U5MPT8
names: Similarity
messages: Belongs to the hemerythrin family.

1345695:CLSA RS16730
gene id: 1345695:CLSA_RS16730
uniprot id: U5MVA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.
messages: Represents a citryl-ACP lyase.

1345695:CLSA RS06310
gene id: 1345695:CLSA_RS06310
uniprot id: U5MRJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS07070
gene id: 1345695:CLSA_RS07070
uniprot id: U5MSQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1345695:CLSA RS10215
gene id: 1345695:CLSA_RS10215
uniprot id: U5MR61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS13345
gene id: 1345695:CLSA_RS13345
uniprot id: U5MT10
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1345695:CLSA RS02505
gene id: 1345695:CLSA_RS02505
uniprot id: U5MPD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1345695:CLSA RS01030
gene id: 1345695:CLSA_RS01030
uniprot id: U5ML48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1345695:CLSA RS14765
gene id: 1345695:CLSA_RS14765
uniprot id: U5MTE3
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

1345695:CLSA RS02880
gene id: 1345695:CLSA_RS02880
uniprot id: U5MLC2
names: Similarity
messages: Belongs to the RutC family.

1345695:CLSA RS00490
gene id: 1345695:CLSA_RS00490
uniprot id: U5MNA1
names: Similarity
messages: Belongs to the UPF0597 family.

1345695:CLSA RS16170
gene id: 1345695:CLSA_RS16170
uniprot id: U5MXW7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS08445
gene id: 1345695:CLSA_RS08445
uniprot id: U5MTE7
names: Similarity
messages: Belongs to the peptidase C40 family.

1345695:CLSA RS01880
gene id: 1345695:CLSA_RS01880
uniprot id: U5MLI0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1345695:CLSA RS20505
gene id: 1345695:CLSA_RS20505
uniprot id: U5N0A7
names: Similarity
messages: Belongs to the peptidase M13 family.

1345695:CLSA RS06520
gene id: 1345695:CLSA_RS06520
uniprot id: U5MP83
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS00380
gene id: 1345695:CLSA_RS00380
uniprot id: U5MKL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1345695:CLSA RS18215
gene id: 1345695:CLSA_RS18215
uniprot id: U5MW26
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1345695:CLSA RS08685
gene id: 1345695:CLSA_RS08685
uniprot id: U5MTJ4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1345695:CLSA RS12390
gene id: 1345695:CLSA_RS12390
uniprot id: U5MRX2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1345695:CLSA RS04970
gene id: 1345695:CLSA_RS04970
uniprot id: U5MNE5
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1345695:CLSA RS20660
gene id: 1345695:CLSA_RS20660
uniprot id: U5MWR7
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1345695:CLSA RS06505
gene id: 1345695:CLSA_RS06505
uniprot id: U5MP12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1345695:CLSA RS00805
gene id: 1345695:CLSA_RS00805
uniprot id: U5MK71
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1345695:CLSA RS15785
gene id: 1345695:CLSA_RS15785
uniprot id: U5MX97
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1345695:CLSA RS01605
gene id: 1345695:CLSA_RS01605
uniprot id: U5MKT2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS20405
gene id: 1345695:CLSA_RS20405
uniprot id: U5N088
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS07125
gene id: 1345695:CLSA_RS07125
uniprot id: U5MPN2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

1345695:CLSA RS01635
gene id: 1345695:CLSA_RS01635
uniprot id: U5MLD7
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

1345695:CLSA RS15450
gene id: 1345695:CLSA_RS15450
uniprot id: U5MUH7
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1345695:CLSA RS07575
gene id: 1345695:CLSA_RS07575
uniprot id: U5MSC7
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1345695:CLSA RS21460
gene id: 1345695:CLSA_RS21460
uniprot id: U5N0X2
names: Similarity
messages: Belongs to the DEAD box helicase family.

1345695:CLSA RS09130
gene id: 1345695:CLSA_RS09130
uniprot id: U5MT72
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS05605
gene id: 1345695:CLSA_RS05605
uniprot id: U5MNI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1345695:CLSA RS19180
gene id: 1345695:CLSA_RS19180
uniprot id: U5MW14
names: Similarity
messages: Belongs to the UPF0473 family.

1345695:CLSA RS06770
gene id: 1345695:CLSA_RS06770
uniprot id: U5MPH6
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1345695:CLSA RS11890
gene id: 1345695:CLSA_RS11890
uniprot id: U5MSG0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS20735
gene id: 1345695:CLSA_RS20735
uniprot id: U5MXF1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1345695:CLSA RS15585
gene id: 1345695:CLSA_RS15585
uniprot id: U5MXN0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1345695:CLSA RS01085
gene id: 1345695:CLSA_RS01085
uniprot id: U5MKY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1345695:CLSA RS14860
gene id: 1345695:CLSA_RS14860
uniprot id: U5MTF6
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS09115
gene id: 1345695:CLSA_RS09115
uniprot id: U5MQQ9
names: Similarity
messages: Belongs to the KdgT transporter family.

1345695:CLSA RS01230
gene id: 1345695:CLSA_RS01230
uniprot id: U5ML89
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1345695:CLSA RS03640
gene id: 1345695:CLSA_RS03640
uniprot id: U5MLS6
names: Similarity
messages: Belongs to the aldose epimerase family.

1345695:CLSA RS10175
gene id: 1345695:CLSA_RS10175
uniprot id: U5MTU4
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS06280
gene id: 1345695:CLSA_RS06280
uniprot id: U5MNW7
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1345695:CLSA RS00950
gene id: 1345695:CLSA_RS00950
uniprot id: U5MP70
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1345695:CLSA RS21750
gene id: 1345695:CLSA_RS21750
uniprot id: U5N0L6
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1345695:CLSA RS05240
gene id: 1345695:CLSA_RS05240
uniprot id: U5MNJ4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

1345695:CLSA RS12055
gene id: 1345695:CLSA_RS12055
uniprot id: U5MVL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1345695:CLSA RS12970
gene id: 1345695:CLSA_RS12970
uniprot id: U5MVJ2
names: Similarity
messages: Belongs to the asp23 family.

1345695:CLSA RS20630
gene id: 1345695:CLSA_RS20630
uniprot id: U5MXH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1345695:CLSA RS00985
gene id: 1345695:CLSA_RS00985
uniprot id: U5MKB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1345695:CLSA RS05995
gene id: 1345695:CLSA_RS05995
uniprot id: U5MS09
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1345695:CLSA RS19405
gene id: 1345695:CLSA_RS19405
uniprot id: U5MZB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1345695:CLSA RS18905
gene id: 1345695:CLSA_RS18905
uniprot id: U5MWK5
names: Subcellular Location Annotation
messages: Cytoplasm

1345695:CLSA RS02785
gene id: 1345695:CLSA_RS02785
uniprot id: U5MPH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

1345695:CLSA RS10125
gene id: 1345695:CLSA_RS10125
uniprot id: U5MUF7
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1345695:CLSA RS13115
gene id: 1345695:CLSA_RS13115
uniprot id: U5MSX0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1345695:CLSA RS06425
gene id: 1345695:CLSA_RS06425
uniprot id: U5MND4
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1345695:CLSA RS13095
gene id: 1345695:CLSA_RS13095
uniprot id: U5MVL6
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

1345695:CLSA RS06135
gene id: 1345695:CLSA_RS06135
uniprot id: U5MRG2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1345695:CLSA RS11960
gene id: 1345695:CLSA_RS11960
uniprot id: U5MSH2
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.

1345695:CLSA RS09945
gene id: 1345695:CLSA_RS09945
uniprot id: U5MUC8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS02645
gene id: 1345695:CLSA_RS02645
uniprot id: U5MM11
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS13615
gene id: 1345695:CLSA_RS13615
uniprot id: U5MVX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1345695:CLSA RS05495
gene id: 1345695:CLSA_RS05495
uniprot id: U5MNN3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1345695:CLSA RS01015
gene id: 1345695:CLSA_RS01015
uniprot id: U5MKW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1345695:CLSA RS03360
gene id: 1345695:CLSA_RS03360
uniprot id: U5MLL2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1345695:CLSA RS01355
gene id: 1345695:CLSA_RS01355
uniprot id: U5MPE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1345695:CLSA RS07965
gene id: 1345695:CLSA_RS07965
uniprot id: U5MSJ5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS21145
gene id: 1345695:CLSA_RS21145
uniprot id: U5N076
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1345695:CLSA RS07105
gene id: 1345695:CLSA_RS07105
uniprot id: U5MNV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1345695:CLSA RS13950
gene id: 1345695:CLSA_RS13950
uniprot id: U5MSU7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1345695:CLSA RS00700
gene id: 1345695:CLSA_RS00700
uniprot id: U5MKZ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1345695:CLSA RS14980
gene id: 1345695:CLSA_RS14980
uniprot id: U5MTH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1345695:CLSA RS06870
gene id: 1345695:CLSA_RS06870
uniprot id: U5MPJ6
names: Similarity
messages: Belongs to the UPF0102 family.

1345695:CLSA RS13605
gene id: 1345695:CLSA_RS13605
uniprot id: U5MTC2
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS08680
gene id: 1345695:CLSA_RS08680
uniprot id: U5MSY4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1345695:CLSA RS16750
gene id: 1345695:CLSA_RS16750
uniprot id: U5MYC3
names: Similarity
messages: Belongs to the CitG/MdcB family.

1345695:CLSA RS15340
gene id: 1345695:CLSA_RS15340
uniprot id: U5MU96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

1345695:CLSA RS21635
gene id: 1345695:CLSA_RS21635
uniprot id: U5N106
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1345695:CLSA RS19490
gene id: 1345695:CLSA_RS19490
uniprot id: U5MW65
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1345695:CLSA RS02310
gene id: 1345695:CLSA_RS02310
uniprot id: U5MLV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

1345695:CLSA RS08620
gene id: 1345695:CLSA_RS08620
uniprot id: U5MPM6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1345695:CLSA RS01115
gene id: 1345695:CLSA_RS01115
uniprot id: U5MNL1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1345695:CLSA RS15850
gene id: 1345695:CLSA_RS15850
uniprot id: U5MTZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS23655
gene id: 1345695:CLSA_RS23655
uniprot id: U5MZJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1345695:CLSA RS08735
gene id: 1345695:CLSA_RS08735
uniprot id: U5MTK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1345695:CLSA RS09275
gene id: 1345695:CLSA_RS09275
uniprot id: U5MQ51
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1345695:CLSA RS13165
gene id: 1345695:CLSA_RS13165
uniprot id: U5MSX9
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS07750
gene id: 1345695:CLSA_RS07750
uniprot id: U5MSF8
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1345695:CLSA RS18425
gene id: 1345695:CLSA_RS18425
uniprot id: U5MYQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS19780
gene id: 1345695:CLSA_RS19780
uniprot id: U5MWU8
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1345695:CLSA RS18045
gene id: 1345695:CLSA_RS18045
uniprot id: U5MV83
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1345695:CLSA RS20550
gene id: 1345695:CLSA_RS20550
uniprot id: U5MZX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS08705
gene id: 1345695:CLSA_RS08705
uniprot id: U5MSY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1345695:CLSA RS01740
gene id: 1345695:CLSA_RS01740
uniprot id: U5MPS9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1345695:CLSA RS12530
gene id: 1345695:CLSA_RS12530
uniprot id: U5MSI5
names: Caution
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1345695:CLSA RS03495
gene id: 1345695:CLSA_RS03495
uniprot id: U5MMA4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1345695:CLSA RS06090
gene id: 1345695:CLSA_RS06090
uniprot id: U5MS27
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

1345695:CLSA RS12560
gene id: 1345695:CLSA_RS12560
uniprot id: U5MVA5
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1345695:CLSA RS16700
gene id: 1345695:CLSA_RS16700
uniprot id: U5MYB3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

1345695:CLSA RS10490
gene id: 1345695:CLSA_RS10490
uniprot id: U5MRJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1345695:CLSA RS10365
gene id: 1345695:CLSA_RS10365
uniprot id: U5MR91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. AI-2 autoinducer porter (TC 3.A.1.2.8) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

1345695:CLSA RS21475
gene id: 1345695:CLSA_RS21475
uniprot id: U5MXW2
names: Subcellular Location Annotation
messages: Cytoplasm

1345695:CLSA RS15945
gene id: 1345695:CLSA_RS15945
uniprot id: U5MXT3
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS21100
gene id: 1345695:CLSA_RS21100
uniprot id: U5N0L4
names: Subcellular Location Annotation
messages: Membrane

1345695:CLSA RS21000
gene id: 1345695:CLSA_RS21000
uniprot id: U5N0K1
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1345695:CLSA RS03140
gene id: 1345695:CLSA_RS03140
uniprot id: U5MM98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1345695:CLSA RS05580
gene id: 1345695:CLSA_RS05580
uniprot id: U5MNI4
names: Similarity
messages: Belongs to the IMPACT family.