1341694:BINDI RS06500
gene id: 1341694:BINDI_RS06500
uniprot id: A0A087VW31
names: Subcellular Location Annotation
messages: Membrane

1341694:BINDI RS02150
gene id: 1341694:BINDI_RS02150
uniprot id: A0A087VTF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1341694:BINDI RS05990
gene id: 1341694:BINDI_RS05990
uniprot id: A0A087VVM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1341694:BINDI RS01995
gene id: 1341694:BINDI_RS01995
uniprot id: A0A087VTJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1341694:BINDI RS06820
gene id: 1341694:BINDI_RS06820
uniprot id: A0A087VW48
names: Subcellular Location Annotation
messages: Membrane

1341694:BINDI RS06475
gene id: 1341694:BINDI_RS06475
uniprot id: A0A087VW28
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1341694:BINDI RS00135
gene id: 1341694:BINDI_RS00135
uniprot id: A0A087VSH5
names: Subcellular Location Annotation
messages: Membrane

1341694:BINDI RS02735
gene id: 1341694:BINDI_RS02735
uniprot id: A0A087VTV6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

1341694:BINDI RS05985
gene id: 1341694:BINDI_RS05985
uniprot id: A0A087VVV2
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1341694:BINDI RS05865
gene id: 1341694:BINDI_RS05865
uniprot id: A0A087VVP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1341694:BINDI RS02630
gene id: 1341694:BINDI_RS02630
uniprot id: A0A087VTX5
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

1341694:BINDI RS03100
gene id: 1341694:BINDI_RS03100
uniprot id: A0A087VTU9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1341694:BINDI RS01285
gene id: 1341694:BINDI_RS01285
uniprot id: A0A087VT20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1341694:BINDI RS00535
gene id: 1341694:BINDI_RS00535
uniprot id: A0A087VSP2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

1341694:BINDI RS00650
gene id: 1341694:BINDI_RS00650
uniprot id: A0A087VSR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1341694:BINDI RS00465
gene id: 1341694:BINDI_RS00465
uniprot id: A0A087VSP0
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

1341694:BINDI RS01730
gene id: 1341694:BINDI_RS01730
uniprot id: A0A087VTE4
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1341694:BINDI RS04970
gene id: 1341694:BINDI_RS04970
uniprot id: A0A087VV83
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1341694:BINDI RS02230
gene id: 1341694:BINDI_RS02230
uniprot id: A0A087VTN7
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1341694:BINDI RS05310
gene id: 1341694:BINDI_RS05310
uniprot id: A0A087VVH9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1341694:BINDI RS00690
gene id: 1341694:BINDI_RS00690
uniprot id: A0A087VSS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1341694:BINDI RS03315
gene id: 1341694:BINDI_RS03315
uniprot id: A0A087VTX3
names: Subcellular Location Annotation
messages: Membrane

1341694:BINDI RS04875
gene id: 1341694:BINDI_RS04875
uniprot id: A0A087VVA0
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1341694:BINDI RS01565
gene id: 1341694:BINDI_RS01565
uniprot id: A0A087VT72
names: Similarity
messages: Belongs to the UPF0237 family.

1341694:BINDI RS00160
gene id: 1341694:BINDI_RS00160
uniprot id: A0A087VSH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1341694:BINDI RS04850
gene id: 1341694:BINDI_RS04850
uniprot id: A0A087VV96
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1341694:BINDI RS06940
gene id: 1341694:BINDI_RS06940
uniprot id: A0A087VW90
names: Subcellular Location Annotation
messages: Membrane

1341694:BINDI RS06910
gene id: 1341694:BINDI_RS06910
uniprot id: A0A087VW47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1341694:BINDI RS01130
gene id: 1341694:BINDI_RS01130
uniprot id: A0A087VT01
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1341694:BINDI RS01655
gene id: 1341694:BINDI_RS01655
uniprot id: A0A087VTC6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1341694:BINDI RS05540
gene id: 1341694:BINDI_RS05540
uniprot id: A0A087VVM1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1341694:BINDI RS01145
gene id: 1341694:BINDI_RS01145
uniprot id: A0A087VSZ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1341694:BINDI RS07545
gene id: 1341694:BINDI_RS07545
uniprot id: A0A087VSE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1341694:BINDI RS02930
gene id: 1341694:BINDI_RS02930
uniprot id: A0A087VU31
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

1341694:BINDI RS03555
gene id: 1341694:BINDI_RS03555
uniprot id: A0A087VUI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1341694:BINDI RS06830
gene id: 1341694:BINDI_RS06830
uniprot id: A0A087VW75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1341694:BINDI RS03680
gene id: 1341694:BINDI_RS03680
uniprot id: A0A087VUE9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1341694:BINDI RS02395
gene id: 1341694:BINDI_RS02395
uniprot id: A0A087VTR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1341694:BINDI RS01700
gene id: 1341694:BINDI_RS01700
uniprot id: A0A087VT99
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1341694:BINDI RS01255
gene id: 1341694:BINDI_RS01255
uniprot id: A0A087VT26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1341694:BINDI RS03940
gene id: 1341694:BINDI_RS03940
uniprot id: A0A087VUK4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1341694:BINDI RS02155
gene id: 1341694:BINDI_RS02155
uniprot id: A0A087VTM3
names: Subcellular Location Annotation
messages: Membrane

1341694:BINDI RS03320
gene id: 1341694:BINDI_RS03320
uniprot id: A0A087VU98
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1341694:BINDI RS05915
gene id: 1341694:BINDI_RS05915
uniprot id: A0A087VVQ1
names: Similarity
messages: Belongs to the peptidase C15 family.

1341694:BINDI RS06265
gene id: 1341694:BINDI_RS06265
uniprot id: A0A087VVW2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1341694:BINDI RS03995
gene id: 1341694:BINDI_RS03995
uniprot id: A0A087VUL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1341694:BINDI RS06150
gene id: 1341694:BINDI_RS06150
uniprot id: A0A087VVQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1341694:BINDI RS03560
gene id: 1341694:BINDI_RS03560
uniprot id: A0A087VUF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1341694:BINDI RS01650
gene id: 1341694:BINDI_RS01650
uniprot id: A0A087VT91
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1341694:BINDI RS00460
gene id: 1341694:BINDI_RS00460
uniprot id: A0A087VSM2
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.
messages: In the C-terminal section; belongs to the trehalose phosphatase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 20 family.

1341694:BINDI RS06300
gene id: 1341694:BINDI_RS06300
uniprot id: A0A087VW00
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1341694:BINDI RS06165
gene id: 1341694:BINDI_RS06165
uniprot id: A0A087VVB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

1341694:BINDI RS01355
gene id: 1341694:BINDI_RS01355
uniprot id: A0A087VT39
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1341694:BINDI RS06670
gene id: 1341694:BINDI_RS06670
uniprot id: A0A087VW27
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1341694:BINDI RS04600
gene id: 1341694:BINDI_RS04600
uniprot id: A0A087VUY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1341694:BINDI RS02085
gene id: 1341694:BINDI_RS02085
uniprot id: A0A087VTH0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1341694:BINDI RS05980
gene id: 1341694:BINDI_RS05980
uniprot id: A0A087VV91
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1341694:BINDI RS06385
gene id: 1341694:BINDI_RS06385
uniprot id: A0A087VW24
names: Similarity
messages: Belongs to the peptidase C69 family.

1341694:BINDI RS01350
gene id: 1341694:BINDI_RS01350
uniprot id: A0A087VT60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1341694:BINDI RS02040
gene id: 1341694:BINDI_RS02040
uniprot id: A0A087VTL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1341694:BINDI RS05455
gene id: 1341694:BINDI_RS05455
uniprot id: A0A087VVG2
names: Similarity
messages: Belongs to the RibF family.

1341694:BINDI RS05360
gene id: 1341694:BINDI_RS05360
uniprot id: A0A087VV29
names: Similarity
messages: Belongs to the peptidase S51 family.

1341694:BINDI RS05660
gene id: 1341694:BINDI_RS05660
uniprot id: A0A087VV60
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1341694:BINDI RS05625
gene id: 1341694:BINDI_RS05625
uniprot id: A0A087VVT0
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1341694:BINDI RS00150
gene id: 1341694:BINDI_RS00150
uniprot id: A0A087VSH9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1341694:BINDI RS05475
gene id: 1341694:BINDI_RS05475
uniprot id: A0A087VVQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1341694:BINDI RS02250
gene id: 1341694:BINDI_RS02250
uniprot id: A0A087VTH1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1341694:BINDI RS03060
gene id: 1341694:BINDI_RS03060
uniprot id: A0A087VTU4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

1341694:BINDI RS03200
gene id: 1341694:BINDI_RS03200
uniprot id: A0A087VU78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1341694:BINDI RS03230
gene id: 1341694:BINDI_RS03230
uniprot id: A0A087VU56
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1341694:BINDI RS03955
gene id: 1341694:BINDI_RS03955
uniprot id: A0A087VUP0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1341694:BINDI RS04835
gene id: 1341694:BINDI_RS04835
uniprot id: A0A087VUR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1341694:BINDI RS02865
gene id: 1341694:BINDI_RS02865
uniprot id: A0A087VU19
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1341694:BINDI RS01210
gene id: 1341694:BINDI_RS01210
uniprot id: A0A087VT05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

1341694:BINDI RS02675
gene id: 1341694:BINDI_RS02675
uniprot id: A0A087VTQ7
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1341694:BINDI RS03800
gene id: 1341694:BINDI_RS03800
uniprot id: A0A087VU80
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1341694:BINDI RS04270
gene id: 1341694:BINDI_RS04270
uniprot id: A0A087VUG4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1341694:BINDI RS02720
gene id: 1341694:BINDI_RS02720
uniprot id: A0A087VTZ4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1341694:BINDI RS02555
gene id: 1341694:BINDI_RS02555
uniprot id: A0A087VTW0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1341694:BINDI RS00785
gene id: 1341694:BINDI_RS00785
uniprot id: A0A087VSU1
names: Subcellular Location Annotation
messages: Membrane

1341694:BINDI RS01500
gene id: 1341694:BINDI_RS01500
uniprot id: A0A087VT66
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1341694:BINDI RS05780
gene id: 1341694:BINDI_RS05780
uniprot id: A0A087VVR3
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1341694:BINDI RS06175
gene id: 1341694:BINDI_RS06175
uniprot id: A0A087VVQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1341694:BINDI RS00645
gene id: 1341694:BINDI_RS00645
uniprot id: A0A087VSQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

1341694:BINDI RS05725
gene id: 1341694:BINDI_RS05725
uniprot id: A0A087VVH7
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1341694:BINDI RS05025
gene id: 1341694:BINDI_RS05025
uniprot id: A0A087VV88
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1341694:BINDI RS04920
gene id: 1341694:BINDI_RS04920
uniprot id: A0A087VV74
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1341694:BINDI RS02005
gene id: 1341694:BINDI_RS02005
uniprot id: A0A087VTJ5
names: Similarity
messages: Belongs to the YggT family.

1341694:BINDI RS03490
gene id: 1341694:BINDI_RS03490
uniprot id: A0A087VU12
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1341694:BINDI RS01310
gene id: 1341694:BINDI_RS01310
uniprot id: A0A087VT27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1341694:BINDI RS01270
gene id: 1341694:BINDI_RS01270
uniprot id: A0A087VT24
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1341694:BINDI RS07145
gene id: 1341694:BINDI_RS07145
uniprot id: A0A087VUS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1341694:BINDI RS04630
gene id: 1341694:BINDI_RS04630
uniprot id: A0A087VUY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1341694:BINDI RS03645
gene id: 1341694:BINDI_RS03645
uniprot id: A0A087VU46
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1341694:BINDI RS01205
gene id: 1341694:BINDI_RS01205
uniprot id: A0A087VT17
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1341694:BINDI RS06425
gene id: 1341694:BINDI_RS06425
uniprot id: A0A087VW20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1341694:BINDI RS06990
gene id: 1341694:BINDI_RS06990
uniprot id: A0A087VW59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1341694:BINDI RS04005
gene id: 1341694:BINDI_RS04005
uniprot id: A0A087VUS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

1341694:BINDI RS00115
gene id: 1341694:BINDI_RS00115
uniprot id: A0A087VSF6
names: Subcellular Location Annotation
messages: Membrane

1341694:BINDI RS02025
gene id: 1341694:BINDI_RS02025
uniprot id: A0A087VTD6
names: Subcellular Location Annotation
messages: Cytoplasm

1341694:BINDI RS01000
gene id: 1341694:BINDI_RS01000
uniprot id: A0A087VSZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1341694:BINDI RS03685
gene id: 1341694:BINDI_RS03685
uniprot id: A0A087VUK6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1341694:BINDI RS05155
gene id: 1341694:BINDI_RS05155
uniprot id: A0A087VVK5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1341694:BINDI RS00640
gene id: 1341694:BINDI_RS00640
uniprot id: A0A087VSR2
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1341694:BINDI RS01060
gene id: 1341694:BINDI_RS01060
uniprot id: A0A087VT02
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1341694:BINDI RS01590
gene id: 1341694:BINDI_RS01590
uniprot id: A0A087VT75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1341694:BINDI RS02485
gene id: 1341694:BINDI_RS02485
uniprot id: A0A087VTS7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1341694:BINDI RS05675
gene id: 1341694:BINDI_RS05675
uniprot id: A0A087VVT6
names: Similarity
messages: Belongs to the IMPACT family.

1341694:BINDI RS04210
gene id: 1341694:BINDI_RS04210
uniprot id: A0A087VUV8
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1341694:BINDI RS02315
gene id: 1341694:BINDI_RS02315
uniprot id: A0A087VTQ9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1341694:BINDI RS06995
gene id: 1341694:BINDI_RS06995
uniprot id: A0A087VW92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1341694:BINDI RS03595
gene id: 1341694:BINDI_RS03595
uniprot id: A0A087VUE6
names: Subcellular Location Annotation
messages: Membrane

1341694:BINDI RS06195
gene id: 1341694:BINDI_RS06195
uniprot id: A0A087VVY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1341694:BINDI RS03355
gene id: 1341694:BINDI_RS03355
uniprot id: A0A087VUE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1341694:BINDI RS05060
gene id: 1341694:BINDI_RS05060
uniprot id: A0A087VV02
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1341694:BINDI RS00975
gene id: 1341694:BINDI_RS00975
uniprot id: A0A087VSY6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1341694:BINDI RS06640
gene id: 1341694:BINDI_RS06640
uniprot id: A0A087VW64
names: Subcellular Location Annotation
messages: Membrane

1341694:BINDI RS04560
gene id: 1341694:BINDI_RS04560
uniprot id: A0A087VV39
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

1341694:BINDI RS03395
gene id: 1341694:BINDI_RS03395
uniprot id: A0A087VUB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1341694:BINDI RS02860
gene id: 1341694:BINDI_RS02860
uniprot id: A0A087VTS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1341694:BINDI RS06020
gene id: 1341694:BINDI_RS06020
uniprot id: A0A087VVN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1341694:BINDI RS05935
gene id: 1341694:BINDI_RS05935
uniprot id: A0A087VVX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1341694:BINDI RS06455
gene id: 1341694:BINDI_RS06455
uniprot id: A0A087VVW4
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1341694:BINDI RS06845
gene id: 1341694:BINDI_RS06845
uniprot id: A0A087VW52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1341694:BINDI RS03025
gene id: 1341694:BINDI_RS03025
uniprot id: A0A087VU84
names: Similarity
messages: Belongs to the UPF0749 family.

1341694:BINDI RS02635
gene id: 1341694:BINDI_RS02635
uniprot id: A0A087VTU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1341694:BINDI RS02020
gene id: 1341694:BINDI_RS02020
uniprot id: A0A087VTJ6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1341694:BINDI RS02280
gene id: 1341694:BINDI_RS02280
uniprot id: A0A087VTP8
names: Similarity
messages: Belongs to the ArsC family.

1341694:BINDI RS04430
gene id: 1341694:BINDI_RS04430
uniprot id: A0A087VUU3
names: Subcellular Location Annotation
messages: Membrane

1341694:BINDI RS04465
gene id: 1341694:BINDI_RS04465
uniprot id: A0A087VUX3
names: Similarity
messages: Belongs to the WXG100 family.

1341694:BINDI RS02755
gene id: 1341694:BINDI_RS02755
uniprot id: A0A087VTZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1341694:BINDI RS02035
gene id: 1341694:BINDI_RS02035
uniprot id: A0A087VTG0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1341694:BINDI RS05470
gene id: 1341694:BINDI_RS05470
uniprot id: A0A087VVD7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1341694:BINDI RS05405
gene id: 1341694:BINDI_RS05405
uniprot id: A0A087VVP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1341694:BINDI RS05200
gene id: 1341694:BINDI_RS05200
uniprot id: A0A087VVG6
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1341694:BINDI RS04315
gene id: 1341694:BINDI_RS04315
uniprot id: A0A087VUV5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1341694:BINDI RS00400
gene id: 1341694:BINDI_RS00400
uniprot id: A0A087VSM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1341694:BINDI RS04215
gene id: 1341694:BINDI_RS04215
uniprot id: A0A087VUU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1341694:BINDI RS03985
gene id: 1341694:BINDI_RS03985
uniprot id: A0A087VUP8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1341694:BINDI RS00590
gene id: 1341694:BINDI_RS00590
uniprot id: A0A087VSP1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1341694:BINDI RS01105
gene id: 1341694:BINDI_RS01105
uniprot id: A0A087VSY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1341694:BINDI RS06005
gene id: 1341694:BINDI_RS06005
uniprot id: A0A087VVR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1341694:BINDI RS02225
gene id: 1341694:BINDI_RS02225
uniprot id: A0A087VTG6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for chromosome condensation and partitioning.

1341694:BINDI RS04625
gene id: 1341694:BINDI_RS04625
uniprot id: A0A087VUZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1341694:BINDI RS01100
gene id: 1341694:BINDI_RS01100
uniprot id: A0A087VSZ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1341694:BINDI RS02200
gene id: 1341694:BINDI_RS02200
uniprot id: A0A087VTG1
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

1341694:BINDI RS05100
gene id: 1341694:BINDI_RS05100
uniprot id: A0A087VVJ6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1341694:BINDI RS05520
gene id: 1341694:BINDI_RS05520
uniprot id: A0A087VVE6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1341694:BINDI RS06565
gene id: 1341694:BINDI_RS06565
uniprot id: A0A087VW11
names: Similarity
messages: Belongs to the P(II) protein family.

1341694:BINDI RS01170
gene id: 1341694:BINDI_RS01170
uniprot id: A0A087VT03
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1341694:BINDI RS06040
gene id: 1341694:BINDI_RS06040
uniprot id: A0A087VVW1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1341694:BINDI RS04995
gene id: 1341694:BINDI_RS04995
uniprot id: A0A087VVB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1341694:BINDI RS03235
gene id: 1341694:BINDI_RS03235
uniprot id: A0A087VUC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1341694:BINDI RS00915
gene id: 1341694:BINDI_RS00915
uniprot id: A0A087VSW5
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1341694:BINDI RS06850
gene id: 1341694:BINDI_RS06850
uniprot id: A0A087VVR2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1341694:BINDI RS04280
gene id: 1341694:BINDI_RS04280
uniprot id: A0A087VUR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1341694:BINDI RS02145
gene id: 1341694:BINDI_RS02145
uniprot id: A0A087VTM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1341694:BINDI RS05940
gene id: 1341694:BINDI_RS05940
uniprot id: A0A087VVQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1341694:BINDI RS02840
gene id: 1341694:BINDI_RS02840
uniprot id: A0A087VTY1
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

1341694:BINDI RS06930
gene id: 1341694:BINDI_RS06930
uniprot id: A0A087VW83
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1341694:BINDI RS00410
gene id: 1341694:BINDI_RS00410
uniprot id: A0A087VSN0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1341694:BINDI RS04805
gene id: 1341694:BINDI_RS04805
uniprot id: A0A087VV37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1341694:BINDI RS04470
gene id: 1341694:BINDI_RS04470
uniprot id: A0A087VUK3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1341694:BINDI RS04080
gene id: 1341694:BINDI_RS04080
uniprot id: A0A087VUT6
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1341694:BINDI RS06535
gene id: 1341694:BINDI_RS06535
uniprot id: A0A087VW50
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1341694:BINDI RS05035
gene id: 1341694:BINDI_RS05035
uniprot id: A0A087VUZ7
names: Similarity
messages: Belongs to the citrate synthase family.

1341694:BINDI RS00210
gene id: 1341694:BINDI_RS00210
uniprot id: A0A087VSI9
names: Similarity
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.

1341694:BINDI RS06355
gene id: 1341694:BINDI_RS06355
uniprot id: A0A087VVU6
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1341694:BINDI RS03325
gene id: 1341694:BINDI_RS03325
uniprot id: A0A087VU72
names: Similarity
messages: Belongs to the fructosamine kinase family.

1341694:BINDI RS01705
gene id: 1341694:BINDI_RS01705
uniprot id: A0A087VTD8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1341694:BINDI RS06335
gene id: 1341694:BINDI_RS06335
uniprot id: A0A087VW17
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1341694:BINDI RS03725
gene id: 1341694:BINDI_RS03725
uniprot id: A0A087VUG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1341694:BINDI RS05255
gene id: 1341694:BINDI_RS05255
uniprot id: A0A087VV20
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1341694:BINDI RS06345
gene id: 1341694:BINDI_RS06345
uniprot id: A0A087VVE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1341694:BINDI RS06960
gene id: 1341694:BINDI_RS06960
uniprot id: A0A087VW55
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1341694:BINDI RS04880
gene id: 1341694:BINDI_RS04880
uniprot id: A0A087VV59
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Homodimer.

1341694:BINDI RS05585
gene id: 1341694:BINDI_RS05585
uniprot id: A0A087VV51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1341694:BINDI RS00840
gene id: 1341694:BINDI_RS00840
uniprot id: A0A087VST7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1341694:BINDI RS03600
gene id: 1341694:BINDI_RS03600
uniprot id: A0A087VUD3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1341694:BINDI RS06480
gene id: 1341694:BINDI_RS06480
uniprot id: A0A087VVW8
names: Similarity
messages: Belongs to the DnaX/STICHEL family.

1341694:BINDI RS02765
gene id: 1341694:BINDI_RS02765
uniprot id: A0A087VU34
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1341694:BINDI RS05505
gene id: 1341694:BINDI_RS05505
uniprot id: A0A087VVR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1341694:BINDI RS05720
gene id: 1341694:BINDI_RS05720
uniprot id: A0A087VVQ4
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1341694:BINDI RS05705
gene id: 1341694:BINDI_RS05705
uniprot id: A0A087VVT9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1341694:BINDI RS02585
gene id: 1341694:BINDI_RS02585
uniprot id: A0A087VTT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1341694:BINDI RS01185
gene id: 1341694:BINDI_RS01185
uniprot id: A0A087VT00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1341694:BINDI RS05240
gene id: 1341694:BINDI_RS05240
uniprot id: A0A087VVA8
names: Similarity
messages: Belongs to the universal stress protein A family.

1341694:BINDI RS02965
gene id: 1341694:BINDI_RS02965
uniprot id: A0A087VU36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1341694:BINDI RS02000
gene id: 1341694:BINDI_RS02000
uniprot id: A0A087VTD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1341694:BINDI RS06450
gene id: 1341694:BINDI_RS06450
uniprot id: A0A087VW25
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

1341694:BINDI RS01695
gene id: 1341694:BINDI_RS01695
uniprot id: A0A087VTE6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1341694:BINDI RS03505
gene id: 1341694:BINDI_RS03505
uniprot id: A0A087VUH5
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1341694:BINDI RS02950
gene id: 1341694:BINDI_RS02950
uniprot id: A0A087VU69
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1341694:BINDI RS03030
gene id: 1341694:BINDI_RS03030
uniprot id: A0A087VU52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

1341694:BINDI RS05620
gene id: 1341694:BINDI_RS05620
uniprot id: A0A087VVG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1341694:BINDI RS00940
gene id: 1341694:BINDI_RS00940
uniprot id: A0A087VSW8
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1341694:BINDI RS01045
gene id: 1341694:BINDI_RS01045
uniprot id: A0A087VSX7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1341694:BINDI RS02925
gene id: 1341694:BINDI_RS02925
uniprot id: A0A087VU64
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1341694:BINDI RS00900
gene id: 1341694:BINDI_RS00900
uniprot id: A0A087VSW6
names: Similarity
messages: Belongs to the DtxR/MntR family.

1341694:BINDI RS01670
gene id: 1341694:BINDI_RS01670
uniprot id: A0A087VTD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1341694:BINDI RS05765
gene id: 1341694:BINDI_RS05765
uniprot id: A0A087VVU7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1341694:BINDI RS06705
gene id: 1341694:BINDI_RS06705
uniprot id: A0A087VVM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1341694:BINDI RS01260
gene id: 1341694:BINDI_RS01260
uniprot id: A0A087VT15
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1341694:BINDI RS02090
gene id: 1341694:BINDI_RS02090
uniprot id: A0A087VTL4
names: Subcellular Location Annotation
messages: Membrane

1341694:BINDI RS06310
gene id: 1341694:BINDI_RS06310
uniprot id: A0A087VW13
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1341694:BINDI RS00945
gene id: 1341694:BINDI_RS00945
uniprot id: A0A087VSV8
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1341694:BINDI RS03520
gene id: 1341694:BINDI_RS03520
uniprot id: A0A087VUD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

1341694:BINDI RS04275
gene id: 1341694:BINDI_RS04275
uniprot id: A0A087VUS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1341694:BINDI RS04530
gene id: 1341694:BINDI_RS04530
uniprot id: A0A087VUW1
names: Function
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1341694:BINDI RS04035
gene id: 1341694:BINDI_RS04035
uniprot id: A0A087VUR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1341694:BINDI RS06765
gene id: 1341694:BINDI_RS06765
uniprot id: A0A087VW77
names: Subcellular Location Annotation
messages: Membrane

1341694:BINDI RS05400
gene id: 1341694:BINDI_RS05400
uniprot id: A0A087VVC8
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

1341694:BINDI RS01970
gene id: 1341694:BINDI_RS01970
uniprot id: A0A087VTI6
names: Subcellular Location Annotation
messages: Membrane

1341694:BINDI RS04375
gene id: 1341694:BINDI_RS04375
uniprot id: A0A087VUU6
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1341694:BINDI RS04040
gene id: 1341694:BINDI_RS04040
uniprot id: A0A087VUC4
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1341694:BINDI RS03340
gene id: 1341694:BINDI_RS03340
uniprot id: A0A087VTX8
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

1341694:BINDI RS06225
gene id: 1341694:BINDI_RS06225
uniprot id: A0A087VVY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1341694:BINDI RS03510
gene id: 1341694:BINDI_RS03510
uniprot id: A0A087VUE7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1341694:BINDI RS00885
gene id: 1341694:BINDI_RS00885
uniprot id: A0A087VSW1
names: Subcellular Location Annotation
messages: Membrane

1341694:BINDI RS05735
gene id: 1341694:BINDI_RS05735
uniprot id: A0A087VVL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1341694:BINDI RS05900
gene id: 1341694:BINDI_RS05900
uniprot id: A0A087VVU0
names: Similarity
messages: Belongs to the peptidase C1 family.

1341694:BINDI RS05610
gene id: 1341694:BINDI_RS05610
uniprot id: A0A087VV54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1341694:BINDI RS03380
gene id: 1341694:BINDI_RS03380
uniprot id: A0A087VUE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1341694:BINDI RS03240
gene id: 1341694:BINDI_RS03240
uniprot id: A0A087VU93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1341694:BINDI RS04550
gene id: 1341694:BINDI_RS04550
uniprot id: A0A087VUX7
names: Similarity
messages: Belongs to the prokaryotic ubiquitin-like protein family.

1341694:BINDI RS02975
gene id: 1341694:BINDI_RS02975
uniprot id: A0A087VU73
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1341694:BINDI RS05270
gene id: 1341694:BINDI_RS05270
uniprot id: A0A087VVM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1341694:BINDI RS06160
gene id: 1341694:BINDI_RS06160
uniprot id: A0A087VVU3
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

1341694:BINDI RS02650
gene id: 1341694:BINDI_RS02650
uniprot id: A0A087VTQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1341694:BINDI RS04605
gene id: 1341694:BINDI_RS04605
uniprot id: A0A087VUX5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1341694:BINDI RS02370
gene id: 1341694:BINDI_RS02370
uniprot id: A0A087VTR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1341694:BINDI RS06735
gene id: 1341694:BINDI_RS06735
uniprot id: A0A087VW63
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1341694:BINDI RS02785
gene id: 1341694:BINDI_RS02785
uniprot id: A0A087VTW5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1341694:BINDI RS05640
gene id: 1341694:BINDI_RS05640
uniprot id: A0A087VVN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1341694:BINDI RS03705
gene id: 1341694:BINDI_RS03705
uniprot id: A0A087VUF6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1341694:BINDI RS03455
gene id: 1341694:BINDI_RS03455
uniprot id: A0A087VUG3
names: Function
names: Similarity
messages: Belongs to the PyrI family.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

1341694:BINDI RS05230
gene id: 1341694:BINDI_RS05230
uniprot id: A0A087VV19
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1341694:BINDI RS01450
gene id: 1341694:BINDI_RS01450
uniprot id: A0A087VT56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1341694:BINDI RS00585
gene id: 1341694:BINDI_RS00585
uniprot id: A0A087VSQ1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1341694:BINDI RS03190
gene id: 1341694:BINDI_RS03190
uniprot id: A0A087VU81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1341694:BINDI RS06235
gene id: 1341694:BINDI_RS06235
uniprot id: A0A087VW03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1341694:BINDI RS00230
gene id: 1341694:BINDI_RS00230
uniprot id: A0A087VSJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1341694:BINDI RS02455
gene id: 1341694:BINDI_RS02455
uniprot id: A0A087VTU5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1341694:BINDI RS00080
gene id: 1341694:BINDI_RS00080
uniprot id: A0A087VSF9
names: Similarity
messages: Belongs to the peptidase S33 family.

1341694:BINDI RS01025
gene id: 1341694:BINDI_RS01025
uniprot id: A0A087VSZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1341694:BINDI RS05630
gene id: 1341694:BINDI_RS05630
uniprot id: A0A087VVJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1341694:BINDI RS05740
gene id: 1341694:BINDI_RS05740
uniprot id: A0A087VV67
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1341694:BINDI RS05685
gene id: 1341694:BINDI_RS05685
uniprot id: A0A087VVK6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1341694:BINDI RS05560
gene id: 1341694:BINDI_RS05560
uniprot id: A0A087VV49
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1341694:BINDI RS07335
gene id: 1341694:BINDI_RS07335
uniprot id: A0A087VV44
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1341694:BINDI RS06400
gene id: 1341694:BINDI_RS06400
uniprot id: A0A087VW16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1341694:BINDI RS00990
gene id: 1341694:BINDI_RS00990
uniprot id: A0A087VSY0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1341694:BINDI RS03415
gene id: 1341694:BINDI_RS03415
uniprot id: A0A087VTZ6
names: Caution
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1341694:BINDI RS02990
gene id: 1341694:BINDI_RS02990
uniprot id: A0A087VU41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Belongs to the TrpC family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1341694:BINDI RS01225
gene id: 1341694:BINDI_RS01225
uniprot id: A0A087VT28
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1341694:BINDI RS02175
gene id: 1341694:BINDI_RS02175
uniprot id: A0A087VTF9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1341694:BINDI RS05015
gene id: 1341694:BINDI_RS05015
uniprot id: A0A087VUZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1341694:BINDI RS00390
gene id: 1341694:BINDI_RS00390
uniprot id: A0A087VSM3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1341694:BINDI RS02655
gene id: 1341694:BINDI_RS02655
uniprot id: A0A087VTY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1341694:BINDI RS03365
gene id: 1341694:BINDI_RS03365
uniprot id: A0A087VTY4
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1341694:BINDI RS03695
gene id: 1341694:BINDI_RS03695
uniprot id: A0A087VU58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1341694:BINDI RS01315
gene id: 1341694:BINDI_RS01315
uniprot id: A0A087VT53
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1341694:BINDI RS06065
gene id: 1341694:BINDI_RS06065
uniprot id: A0A087VVW5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1341694:BINDI RS05700
gene id: 1341694:BINDI_RS05700
uniprot id: A0A087VVH3
names: Subcellular Location Annotation
messages: Membrane

1341694:BINDI RS05575
gene id: 1341694:BINDI_RS05575
uniprot id: A0A087VVS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1341694:BINDI RS03360
gene id: 1341694:BINDI_RS03360
uniprot id: A0A087VUB1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1341694:BINDI RS05080
gene id: 1341694:BINDI_RS05080
uniprot id: A0A087VVB7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1341694:BINDI RS05095
gene id: 1341694:BINDI_RS05095
uniprot id: A0A087VV95
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1341694:BINDI RS04540
gene id: 1341694:BINDI_RS04540
uniprot id: A0A087VUY3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1341694:BINDI RS00980
gene id: 1341694:BINDI_RS00980
uniprot id: A0A087VSW7
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1341694:BINDI RS01980
gene id: 1341694:BINDI_RS01980
uniprot id: A0A087VTJ2
names: Similarity
messages: Belongs to the UPF0045 family.

1341694:BINDI RS01955
gene id: 1341694:BINDI_RS01955
uniprot id: A0A087VTI9
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1341694:BINDI RS06190
gene id: 1341694:BINDI_RS06190
uniprot id: A0A087VVC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1341694:BINDI RS02450
gene id: 1341694:BINDI_RS02450
uniprot id: A0A087VTN1
names: Subcellular Location Annotation
messages: Cell membrane

1341694:BINDI RS02770
gene id: 1341694:BINDI_RS02770
uniprot id: A0A087VU05
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1341694:BINDI RS00715
gene id: 1341694:BINDI_RS00715
uniprot id: A0A087VSS9
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1341694:BINDI RS01880
gene id: 1341694:BINDI_RS01880
uniprot id: A0A087VTH8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1341694:BINDI RS02240
gene id: 1341694:BINDI_RS02240
uniprot id: A0A087VTP3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1341694:BINDI RS05380
gene id: 1341694:BINDI_RS05380
uniprot id: A0A087VVP0
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1341694:BINDI RS05565
gene id: 1341694:BINDI_RS05565
uniprot id: A0A087VVM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1341694:BINDI RS01800
gene id: 1341694:BINDI_RS01800
uniprot id: A0A087VTA5
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1341694:BINDI RS06805
gene id: 1341694:BINDI_RS06805
uniprot id: A0A087VW73
names: Similarity
messages: Belongs to the UPF0423 family.

1341694:BINDI RS03330
gene id: 1341694:BINDI_RS03330
uniprot id: A0A087VUD8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1341694:BINDI RS04220
gene id: 1341694:BINDI_RS04220
uniprot id: A0A087VUF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1341694:BINDI RS01360
gene id: 1341694:BINDI_RS01360
uniprot id: A0A087VT57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1341694:BINDI RS06865
gene id: 1341694:BINDI_RS06865
uniprot id: A0A087VW57
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1341694:BINDI RS04390
gene id: 1341694:BINDI_RS04390
uniprot id: A0A087VUW4
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1341694:BINDI RS03630
gene id: 1341694:BINDI_RS03630
uniprot id: A0A087VUD9
names: Subcellular Location Annotation
messages: Membrane

1341694:BINDI RS02550
gene id: 1341694:BINDI_RS02550
uniprot id: A0A087VTP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1341694:BINDI RS01645
gene id: 1341694:BINDI_RS01645
uniprot id: A0A087VTD3
names: Subcellular Location Annotation
messages: Membrane

1341694:BINDI RS04720
gene id: 1341694:BINDI_RS04720
uniprot id: A0A087VUP6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1341694:BINDI RS03345
gene id: 1341694:BINDI_RS03345
uniprot id: A0A087VUA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1341694:BINDI RS02010
gene id: 1341694:BINDI_RS02010
uniprot id: A0A087VTF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

1341694:BINDI RS00665
gene id: 1341694:BINDI_RS00665
uniprot id: A0A087VSR9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

1341694:BINDI RS01835
gene id: 1341694:BINDI_RS01835
uniprot id: A0A087VTB8
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).

1341694:BINDI RS02745
gene id: 1341694:BINDI_RS02745
uniprot id: A0A087VTZ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1341694:BINDI RS02730
gene id: 1341694:BINDI_RS02730
uniprot id: A0A087VTZ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

1341694:BINDI RS03740
gene id: 1341694:BINDI_RS03740
uniprot id: A0A087VUJ6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1341694:BINDI RS06205
gene id: 1341694:BINDI_RS06205
uniprot id: A0A087VVZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1341694:BINDI RS03580
gene id: 1341694:BINDI_RS03580
uniprot id: A0A087VUJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1341694:BINDI RS03675
gene id: 1341694:BINDI_RS03675
uniprot id: A0A087VUF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1341694:BINDI RS00550
gene id: 1341694:BINDI_RS00550
uniprot id: A0A087VSP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1341694:BINDI RS06460
gene id: 1341694:BINDI_RS06460
uniprot id: A0A087VW37
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1341694:BINDI RS05815
gene id: 1341694:BINDI_RS05815
uniprot id: A0A087VVV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1341694:BINDI RS05580
gene id: 1341694:BINDI_RS05580
uniprot id: A0A087VVI3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1341694:BINDI RS06010
gene id: 1341694:BINDI_RS06010
uniprot id: A0A087VV94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1341694:BINDI RS06000
gene id: 1341694:BINDI_RS06000
uniprot id: A0A087VVX6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1341694:BINDI RS06410
gene id: 1341694:BINDI_RS06410
uniprot id: A0A087VW29
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

1341694:BINDI RS00070
gene id: 1341694:BINDI_RS00070
uniprot id: A0A087VSG1
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1341694:BINDI RS06045
gene id: 1341694:BINDI_RS06045
uniprot id: A0A087VVN8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1341694:BINDI RS05040
gene id: 1341694:BINDI_RS05040
uniprot id: A0A087VVE0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1341694:BINDI RS02615
gene id: 1341694:BINDI_RS02615
uniprot id: A0A087VU03
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1341694:BINDI RS03755
gene id: 1341694:BINDI_RS03755
uniprot id: A0A087VUG7
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1341694:BINDI RS00565
gene id: 1341694:BINDI_RS00565
uniprot id: A0A087VSN4
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1341694:BINDI RS06170
gene id: 1341694:BINDI_RS06170
uniprot id: A0A087VVX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane

1341694:BINDI RS07005
gene id: 1341694:BINDI_RS07005
uniprot id: A0A087VW74
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1341694:BINDI RS04290
gene id: 1341694:BINDI_RS04290
uniprot id: A0A087VUV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1341694:BINDI RS01985
gene id: 1341694:BINDI_RS01985
uniprot id: A0A087VTE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1341694:BINDI RS00720
gene id: 1341694:BINDI_RS00720
uniprot id: A0A087VSR7
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Belongs to the HIBADH-related family.

1341694:BINDI RS05375
gene id: 1341694:BINDI_RS05375
uniprot id: A0A087VVC5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1341694:BINDI RS02440
gene id: 1341694:BINDI_RS02440
uniprot id: A0A087VTW8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1341694:BINDI RS01415
gene id: 1341694:BINDI_RS01415
uniprot id: A0A087VT45
names: Subcellular Location Annotation
messages: Membrane

1341694:BINDI RS04940
gene id: 1341694:BINDI_RS04940
uniprot id: A0A087VUT0
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1341694:BINDI RS05785
gene id: 1341694:BINDI_RS05785
uniprot id: A0A087VVI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1341694:BINDI RS02985
gene id: 1341694:BINDI_RS02985
uniprot id: A0A087VTT4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1341694:BINDI RS04300
gene id: 1341694:BINDI_RS04300
uniprot id: A0A087VUT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1341694:BINDI RS04985
gene id: 1341694:BINDI_RS04985
uniprot id: A0A087VVA3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1341694:BINDI RS04795
gene id: 1341694:BINDI_RS04795
uniprot id: A0A087VV18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1341694:BINDI RS05605
gene id: 1341694:BINDI_RS05605
uniprot id: A0A087VVI8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1341694:BINDI RS00195
gene id: 1341694:BINDI_RS00195
uniprot id: A0A087VSI0
names: Subcellular Location Annotation
messages: Membrane

1341694:BINDI RS03830
gene id: 1341694:BINDI_RS03830
uniprot id: A0A087VU85
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1341694:BINDI RS02535
gene id: 1341694:BINDI_RS02535
uniprot id: A0A087VTT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1341694:BINDI RS00345
gene id: 1341694:BINDI_RS00345
uniprot id: A0A087VSL0
names: Subcellular Location Annotation
messages: Membrane

1341694:BINDI RS00010
gene id: 1341694:BINDI_RS00010
uniprot id: A0A087VSE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1341694:BINDI RS03420
gene id: 1341694:BINDI_RS03420
uniprot id: A0A087VUB6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1341694:BINDI RS01735
gene id: 1341694:BINDI_RS01735
uniprot id: A0A087VTD4
names: Subcellular Location Annotation
messages: Membrane

1341694:BINDI RS04910
gene id: 1341694:BINDI_RS04910
uniprot id: A0A087VV66
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1341694:BINDI RS05615
gene id: 1341694:BINDI_RS05615
uniprot id: A0A087VVN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1341694:BINDI RS04155
gene id: 1341694:BINDI_RS04155
uniprot id: A0A087VUP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1341694:BINDI RS04975
gene id: 1341694:BINDI_RS04975
uniprot id: A0A087VV63
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

1341694:BINDI RS03615
gene id: 1341694:BINDI_RS03615
uniprot id: A0A087VU40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1341694:BINDI RS05590
gene id: 1341694:BINDI_RS05590
uniprot id: A0A087VVM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1341694:BINDI RS03080
gene id: 1341694:BINDI_RS03080
uniprot id: A0A087VU62
names: Similarity
messages: Belongs to the UDPGP type 1 family.

1341694:BINDI RS03770
gene id: 1341694:BINDI_RS03770
uniprot id: A0A087VU75
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1341694:BINDI RS01960
gene id: 1341694:BINDI_RS01960
uniprot id: A0A087VTE2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1341694:BINDI RS06795
gene id: 1341694:BINDI_RS06795
uniprot id: A0A087VW44
names: Subcellular Location Annotation
messages: Membrane

1341694:BINDI RS05135
gene id: 1341694:BINDI_RS05135
uniprot id: A0A087VVC4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1341694:BINDI RS04585
gene id: 1341694:BINDI_RS04585
uniprot id: A0A087VV43
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1341694:BINDI RS02545
gene id: 1341694:BINDI_RS02545
uniprot id: A0A087VTV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1341694:BINDI RS05695
gene id: 1341694:BINDI_RS05695
uniprot id: A0A087VVP9
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1341694:BINDI RS05545
gene id: 1341694:BINDI_RS05545
uniprot id: A0A087VVE9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1341694:BINDI RS06070
gene id: 1341694:BINDI_RS06070
uniprot id: A0A087VVP2
names: Similarity
messages: Belongs to the RutC family.

1341694:BINDI RS03860
gene id: 1341694:BINDI_RS03860
uniprot id: A0A087VUI7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1341694:BINDI RS05165
gene id: 1341694:BINDI_RS05165
uniprot id: A0A087VV14
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1341694:BINDI RS03445
gene id: 1341694:BINDI_RS03445
uniprot id: A0A087VUB9
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1341694:BINDI RS01660
gene id: 1341694:BINDI_RS01660
uniprot id: A0A087VTB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1341694:BINDI RS06415
gene id: 1341694:BINDI_RS06415
uniprot id: A0A087VVY5
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1341694:BINDI RS00635
gene id: 1341694:BINDI_RS00635
uniprot id: A0A087VSP9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1341694:BINDI RS01475
gene id: 1341694:BINDI_RS01475
uniprot id: A0A087VT62
names: Similarity
messages: Belongs to the thioredoxin family.

1341694:BINDI RS06185
gene id: 1341694:BINDI_RS06185
uniprot id: A0A087VVU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1341694:BINDI RS01875
gene id: 1341694:BINDI_RS01875
uniprot id: A0A087VTB7
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1341694:BINDI RS05385
gene id: 1341694:BINDI_RS05385
uniprot id: A0A087VVF1
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1341694:BINDI RS06435
gene id: 1341694:BINDI_RS06435
uniprot id: A0A087VW33
names: Subcellular Location Annotation
messages: Membrane

1341694:BINDI RS06570
gene id: 1341694:BINDI_RS06570
uniprot id: A0A087VVJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1341694:BINDI RS02780
gene id: 1341694:BINDI_RS02780
uniprot id: A0A087VU04
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1341694:BINDI RS00935
gene id: 1341694:BINDI_RS00935
uniprot id: A0A087VSX5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1341694:BINDI RS00580
gene id: 1341694:BINDI_RS00580
uniprot id: A0A087VSN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1341694:BINDI RS00255
gene id: 1341694:BINDI_RS00255
uniprot id: A0A087VSJ8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1341694:BINDI RS02945
gene id: 1341694:BINDI_RS02945
uniprot id: A0A087VU02
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1341694:BINDI RS05500
gene id: 1341694:BINDI_RS05500
uniprot id: A0A087VVE1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1341694:BINDI RS05645
gene id: 1341694:BINDI_RS05645
uniprot id: A0A087VVG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1341694:BINDI RS03960
gene id: 1341694:BINDI_RS03960
uniprot id: A0A087VUB2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1341694:BINDI RS05105
gene id: 1341694:BINDI_RS05105
uniprot id: A0A087VVC1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1341694:BINDI RS02695
gene id: 1341694:BINDI_RS02695
uniprot id: A0A087VTZ0
names: Function
names: Similarity
messages: Belongs to the vsr family.
messages: May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.

1341694:BINDI RS03210
gene id: 1341694:BINDI_RS03210
uniprot id: A0A087VUB5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1341694:BINDI RS05005
gene id: 1341694:BINDI_RS05005
uniprot id: A0A087VVI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1341694:BINDI RS05895
gene id: 1341694:BINDI_RS05895
uniprot id: A0A087VV82
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1341694:BINDI RS01555
gene id: 1341694:BINDI_RS01555
uniprot id: A0A087VTA3
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

1341694:BINDI RS05570
gene id: 1341694:BINDI_RS05570
uniprot id: A0A087VVF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1341694:BINDI RS03260
gene id: 1341694:BINDI_RS03260
uniprot id: A0A087VUC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1341694:BINDI RS05510
gene id: 1341694:BINDI_RS05510
uniprot id: A0A087VVG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1341694:BINDI RS05525
gene id: 1341694:BINDI_RS05525
uniprot id: A0A087VVR5
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1341694:BINDI RS04595
gene id: 1341694:BINDI_RS04595
uniprot id: A0A087VUM2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1341694:BINDI RS04265
gene id: 1341694:BINDI_RS04265
uniprot id: A0A087VUV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1341694:BINDI RS02905
gene id: 1341694:BINDI_RS02905
uniprot id: A0A087VU26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1341694:BINDI RS02305
gene id: 1341694:BINDI_RS02305
uniprot id: A0A087VTQ2
names: Similarity
messages: Belongs to the asparagine synthetase family.

1341694:BINDI RS04635
gene id: 1341694:BINDI_RS04635
uniprot id: A0A087VV55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1341694:BINDI RS05665
gene id: 1341694:BINDI_RS05665
uniprot id: A0A087VVP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1341694:BINDI RS06810
gene id: 1341694:BINDI_RS06810
uniprot id: A0A087VW26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1341694:BINDI RS05515
gene id: 1341694:BINDI_RS05515
uniprot id: A0A087VVL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1341694:BINDI RS01005
gene id: 1341694:BINDI_RS01005
uniprot id: A0A087VSX3
names: Subcellular Location Annotation
messages: Membrane

1341694:BINDI RS02410
gene id: 1341694:BINDI_RS02410
uniprot id: A0A087VTN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1341694:BINDI RS06200
gene id: 1341694:BINDI_RS06200
uniprot id: A0A087VVR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1341694:BINDI RS00380
gene id: 1341694:BINDI_RS00380
uniprot id: A0A087VSM5
names: Subcellular Location Annotation
messages: Membrane

1341694:BINDI RS06305
gene id: 1341694:BINDI_RS06305
uniprot id: A0A087VVT5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1341694:BINDI RS05595
gene id: 1341694:BINDI_RS05595
uniprot id: A0A087VVF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1341694:BINDI RS05870
gene id: 1341694:BINDI_RS05870
uniprot id: A0A087VV80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1341694:BINDI RS06360
gene id: 1341694:BINDI_RS06360
uniprot id: A0A087VW21
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1341694:BINDI RS01420
gene id: 1341694:BINDI_RS01420
uniprot id: A0A087VT77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1341694:BINDI RS01365
gene id: 1341694:BINDI_RS01365
uniprot id: A0A087VT46
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1341694:BINDI RS06760
gene id: 1341694:BINDI_RS06760
uniprot id: A0A087VW18
names: Similarity
messages: Belongs to the cytochrome P450 family.

1341694:BINDI RS05395
gene id: 1341694:BINDI_RS05395
uniprot id: A0A087VVJ4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1341694:BINDI RS00190
gene id: 1341694:BINDI_RS00190
uniprot id: A0A087VSH3
names: Similarity
messages: Belongs to the Dps family.

1341694:BINDI RS01690
gene id: 1341694:BINDI_RS01690
uniprot id: A0A087VT90
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1341694:BINDI RS06180
gene id: 1341694:BINDI_RS06180
uniprot id: A0A087VVZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1341694:BINDI RS02760
gene id: 1341694:BINDI_RS02760
uniprot id: A0A087VTW1
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1341694:BINDI RS00955
gene id: 1341694:BINDI_RS00955
uniprot id: A0A087VSW2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1341694:BINDI RS01065
gene id: 1341694:BINDI_RS01065
uniprot id: A0A087VSY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1341694:BINDI RS02160
gene id: 1341694:BINDI_RS02160
uniprot id: A0A087VTI3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1341694:BINDI RS00755
gene id: 1341694:BINDI_RS00755
uniprot id: A0A087VST9
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1341694:BINDI RS00245
gene id: 1341694:BINDI_RS00245
uniprot id: A0A087VSJ0
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

1341694:BINDI RS03795
gene id: 1341694:BINDI_RS03795
uniprot id: A0A087VUK7
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1341694:BINDI RS01965
gene id: 1341694:BINDI_RS01965
uniprot id: A0A087VTJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

1341694:BINDI RS05415
gene id: 1341694:BINDI_RS05415
uniprot id: A0A087VVJ8
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1341694:BINDI RS05445
gene id: 1341694:BINDI_RS05445
uniprot id: A0A087VVD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1341694:BINDI RS02515
gene id: 1341694:BINDI_RS02515
uniprot id: A0A087VTY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1341694:BINDI RS03575
gene id: 1341694:BINDI_RS03575
uniprot id: A0A087VUC7
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1341694:BINDI RS06035
gene id: 1341694:BINDI_RS06035
uniprot id: A0A087VV98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1341694:BINDI RS05180
gene id: 1341694:BINDI_RS05180
uniprot id: A0A087VVK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1341694:BINDI RS01240
gene id: 1341694:BINDI_RS01240
uniprot id: A0A087VT37
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1341694:BINDI RS05300
gene id: 1341694:BINDI_RS05300
uniprot id: A0A087VVE2
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1341694:BINDI RS05460
gene id: 1341694:BINDI_RS05460
uniprot id: A0A087VV40
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1341694:BINDI RS03010
gene id: 1341694:BINDI_RS03010
uniprot id: A0A087VTT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1341694:BINDI RS04590
gene id: 1341694:BINDI_RS04590
uniprot id: A0A087VUY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1341694:BINDI RS04730
gene id: 1341694:BINDI_RS04730
uniprot id: A0A087VUZ9
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1341694:BINDI RS01595
gene id: 1341694:BINDI_RS01595
uniprot id: A0A087VTB9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1341694:BINDI RS03650
gene id: 1341694:BINDI_RS03650
uniprot id: A0A087VUF4
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1341694:BINDI RS04360
gene id: 1341694:BINDI_RS04360
uniprot id: A0A087VUY8
names: Similarity
messages: Belongs to the glutamine synthetase family.

1341694:BINDI RS00030
gene id: 1341694:BINDI_RS00030
uniprot id: A0A087VSE6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1341694:BINDI RS04840
gene id: 1341694:BINDI_RS04840
uniprot id: A0A087VV57
names: Similarity
messages: Belongs to the GARS family.

1341694:BINDI RS03275
gene id: 1341694:BINDI_RS03275
uniprot id: A0A087VU91
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1341694:BINDI RS03000
gene id: 1341694:BINDI_RS03000
uniprot id: A0A087VU79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1341694:BINDI RS01790
gene id: 1341694:BINDI_RS01790
uniprot id: A0A087VTF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1341694:BINDI RS00595
gene id: 1341694:BINDI_RS00595
uniprot id: A0A087VSR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1341694:BINDI RS00710
gene id: 1341694:BINDI_RS00710
uniprot id: A0A087VSR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1341694:BINDI RS02595
gene id: 1341694:BINDI_RS02595
uniprot id: A0A087VTW9
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

1341694:BINDI RS03450
gene id: 1341694:BINDI_RS03450
uniprot id: A0A087VU99
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1341694:BINDI RS01885
gene id: 1341694:BINDI_RS01885
uniprot id: A0A087VTC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

1341694:BINDI RS03410
gene id: 1341694:BINDI_RS03410
uniprot id: A0A087VUC3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1341694:BINDI RS00830
gene id: 1341694:BINDI_RS00830
uniprot id: A0A087VSV4
names: Subcellular Location Annotation
messages: Membrane

1341694:BINDI RS00205
gene id: 1341694:BINDI_RS00205
uniprot id: A0A087VSI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm

1341694:BINDI RS03430
gene id: 1341694:BINDI_RS03430
uniprot id: A0A087VUF8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1341694:BINDI RS02980
gene id: 1341694:BINDI_RS02980
uniprot id: A0A087VU42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1341694:BINDI RS02500
gene id: 1341694:BINDI_RS02500
uniprot id: A0A087VTP0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1341694:BINDI RS06210
gene id: 1341694:BINDI_RS06210
uniprot id: A0A087VVV3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1341694:BINDI RS02955
gene id: 1341694:BINDI_RS02955
uniprot id: A0A087VU37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1341694:BINDI RS06520
gene id: 1341694:BINDI_RS06520
uniprot id: A0A087VVI0
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1341694:BINDI RS00370
gene id: 1341694:BINDI_RS00370
uniprot id: A0A087VSL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1341694:BINDI RS03760
gene id: 1341694:BINDI_RS03760
uniprot id: A0A087VUL8
names: Similarity
messages: Belongs to the XFP family.

1341694:BINDI RS05845
gene id: 1341694:BINDI_RS05845
uniprot id: A0A087VVN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1341694:BINDI RS01685
gene id: 1341694:BINDI_RS01685
uniprot id: A0A087VTC1
names: Similarity
messages: Belongs to the peptidase M1 family.

1341694:BINDI RS03565
gene id: 1341694:BINDI_RS03565
uniprot id: A0A087VU30
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1341694:BINDI RS06915
gene id: 1341694:BINDI_RS06915
uniprot id: A0A087VW89
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1341694:BINDI RS04865
gene id: 1341694:BINDI_RS04865
uniprot id: A0A087VV64
names: Similarity
messages: Belongs to the Fur family.

1341694:BINDI RS04065
gene id: 1341694:BINDI_RS04065
uniprot id: A0A087VUC8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1341694:BINDI RS00120
gene id: 1341694:BINDI_RS00120
uniprot id: A0A087VSG4
names: Subcellular Location Annotation
messages: Membrane

1341694:BINDI RS05420
gene id: 1341694:BINDI_RS05420
uniprot id: A0A087VVD1
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

1341694:BINDI RS02700
gene id: 1341694:BINDI_RS02700
uniprot id: A0A087VTR1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1341694:BINDI RS05925
gene id: 1341694:BINDI_RS05925
uniprot id: A0A087VVU4
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1341694:BINDI RS05600
gene id: 1341694:BINDI_RS05600
uniprot id: A0A087VVS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1341694:BINDI RS04050
gene id: 1341694:BINDI_RS04050
uniprot id: A0A087VUM7
names: Similarity
messages: Belongs to the peptidase S33 family.

1341694:BINDI RS05975
gene id: 1341694:BINDI_RS05975
uniprot id: A0A087VVR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1341694:BINDI RS05555
gene id: 1341694:BINDI_RS05555
uniprot id: A0A087VVH8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1341694:BINDI RS05490
gene id: 1341694:BINDI_RS05490
uniprot id: A0A087VV41
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1341694:BINDI RS01215
gene id: 1341694:BINDI_RS01215
uniprot id: A0A087VT33
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1341694:BINDI RS02790
gene id: 1341694:BINDI_RS02790
uniprot id: A0A087VU39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1341694:BINDI RS05850
gene id: 1341694:BINDI_RS05850
uniprot id: A0A087VV78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1341694:BINDI RS04295
gene id: 1341694:BINDI_RS04295
uniprot id: A0A087VUG9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1341694:BINDI RS03665
gene id: 1341694:BINDI_RS03665
uniprot id: A0A087VUH9
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1341694:BINDI RS05550
gene id: 1341694:BINDI_RS05550
uniprot id: A0A087VVS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1341694:BINDI RS06050
gene id: 1341694:BINDI_RS06050
uniprot id: A0A087VVY3
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1341694:BINDI RS06015
gene id: 1341694:BINDI_RS06015
uniprot id: A0A087VVV8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1341694:BINDI RS04435
gene id: 1341694:BINDI_RS04435
uniprot id: A0A087VV03
names: Similarity
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Homohexamer. The oligomerization is ATP-dependent.

1341694:BINDI RS01870
gene id: 1341694:BINDI_RS01870
uniprot id: A0A087VTG3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1341694:BINDI RS02805
gene id: 1341694:BINDI_RS02805
uniprot id: A0A087VU08
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1341694:BINDI RS02205
gene id: 1341694:BINDI_RS02205
uniprot id: A0A087VTN3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1341694:BINDI RS03215
gene id: 1341694:BINDI_RS03215
uniprot id: A0A087VU87
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1341694:BINDI RS05635
gene id: 1341694:BINDI_RS05635
uniprot id: A0A087VV56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1341694:BINDI RS00790
gene id: 1341694:BINDI_RS00790
uniprot id: A0A087VSS6
names: Subcellular Location Annotation
messages: Membrane

1341694:BINDI RS00015
gene id: 1341694:BINDI_RS00015
uniprot id: A0A087VSE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1341694:BINDI RS03895
gene id: 1341694:BINDI_RS03895
uniprot id: A0A087VUP7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.

1341694:BINDI RS00985
gene id: 1341694:BINDI_RS00985
uniprot id: A0A087VSY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1341694:BINDI RS03700
gene id: 1341694:BINDI_RS03700
uniprot id: A0A087VUG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1341694:BINDI RS03195
gene id: 1341694:BINDI_RS03195
uniprot id: A0A087VTW6
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1341694:BINDI RS02195
gene id: 1341694:BINDI_RS02195
uniprot id: A0A087VTM7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

1341694:BINDI RS01300
gene id: 1341694:BINDI_RS01300
uniprot id: A0A087VT44
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1341694:BINDI RS04170
gene id: 1341694:BINDI_RS04170
uniprot id: A0A087VUE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1341694:BINDI RS02055
gene id: 1341694:BINDI_RS02055
uniprot id: A0A087VTK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1341694:BINDI RS04045
gene id: 1341694:BINDI_RS04045
uniprot id: A0A087VUM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1341694:BINDI RS07720
gene id: 1341694:BINDI_RS07720
uniprot id: A0A087VVA7
names: Similarity
messages: Belongs to the internalin family.

1341694:BINDI RS00575
gene id: 1341694:BINDI_RS00575
uniprot id: A0A087VSQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1341694:BINDI RS03405
gene id: 1341694:BINDI_RS03405
uniprot id: A0A087VUF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1341694:BINDI RS01815
gene id: 1341694:BINDI_RS01815
uniprot id: A0A087VTF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

1341694:BINDI RS04620
gene id: 1341694:BINDI_RS04620
uniprot id: A0A087VUM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1341694:BINDI RS00855
gene id: 1341694:BINDI_RS00855
uniprot id: A0A087VSV9
names: Subcellular Location Annotation
messages: Membrane

1341694:BINDI RS05195
gene id: 1341694:BINDI_RS05195
uniprot id: A0A087VV15
names: Function
names: Similarity
messages: Abolishes the inhibitory effect of tetracyclin on protein synthesis by a non-covalent modification of the ribosomes.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1341694:BINDI RS03015
gene id: 1341694:BINDI_RS03015
uniprot id: A0A087VU45
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1341694:BINDI RS02320
gene id: 1341694:BINDI_RS02320
uniprot id: A0A087VTQ0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1341694:BINDI RS02275
gene id: 1341694:BINDI_RS02275
uniprot id: A0A087VTH7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1341694:BINDI RS00200
gene id: 1341694:BINDI_RS00200
uniprot id: A0A087VSH1
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Reversible hydration of carbon dioxide.

1341694:BINDI RS00285
gene id: 1341694:BINDI_RS00285
uniprot id: A0A087VSK3
names: Similarity
messages: Belongs to the UPF0749 family.

1341694:BINDI RS05650
gene id: 1341694:BINDI_RS05650
uniprot id: A0A087VVT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1341694:BINDI RS03280
gene id: 1341694:BINDI_RS03280
uniprot id: A0A087VU66
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1341694:BINDI RS02105
gene id: 1341694:BINDI_RS02105
uniprot id: A0A087VTL3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1341694:BINDI RS03775
gene id: 1341694:BINDI_RS03775
uniprot id: A0A087VUH4
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1341694:BINDI RS01515
gene id: 1341694:BINDI_RS01515
uniprot id: A0A087VT63
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1341694:BINDI RS04820
gene id: 1341694:BINDI_RS04820
uniprot id: A0A087VV23
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1341694:BINDI RS05050
gene id: 1341694:BINDI_RS05050
uniprot id: A0A087VVJ0
names: Similarity
messages: Belongs to the peptidase M13 family.

1341694:BINDI RS02870
gene id: 1341694:BINDI_RS02870
uniprot id: A0A087VTY6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1341694:BINDI RS05030
gene id: 1341694:BINDI_RS05030
uniprot id: A0A087VVB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1341694:BINDI RS04325
gene id: 1341694:BINDI_RS04325
uniprot id: A0A087VUT7
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1341694:BINDI RS01380
gene id: 1341694:BINDI_RS01380
uniprot id: A0A087VT42
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

1341694:BINDI RS03820
gene id: 1341694:BINDI_RS03820
uniprot id: A0A087VUM9
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

1341694:BINDI RS02270
gene id: 1341694:BINDI_RS02270
uniprot id: A0A087VTN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1341694:BINDI RS04255
gene id: 1341694:BINDI_RS04255
uniprot id: A0A087VUQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1341694:BINDI RS04870
gene id: 1341694:BINDI_RS04870
uniprot id: A0A087VV38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1341694:BINDI RS03005
gene id: 1341694:BINDI_RS03005
uniprot id: A0A087VU48
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1341694:BINDI RS01570
gene id: 1341694:BINDI_RS01570
uniprot id: A0A087VTB4
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

1341694:BINDI RS01070
gene id: 1341694:BINDI_RS01070
uniprot id: A0A087VSZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1341694:BINDI RS03225
gene id: 1341694:BINDI_RS03225
uniprot id: A0A087VU82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1341694:BINDI RS02490
gene id: 1341694:BINDI_RS02490
uniprot id: A0A087VTX9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1341694:BINDI RS04935
gene id: 1341694:BINDI_RS04935
uniprot id: A0A087VV71
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1341694:BINDI RS03440
gene id: 1341694:BINDI_RS03440
uniprot id: A0A087VU01
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1341694:BINDI RS02190
gene id: 1341694:BINDI_RS02190
uniprot id: A0A087VTN4
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1341694:BINDI RS04640
gene id: 1341694:BINDI_RS04640
uniprot id: A0A087VUZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1341694:BINDI RS02825
gene id: 1341694:BINDI_RS02825
uniprot id: A0A087VU14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1341694:BINDI RS05085
gene id: 1341694:BINDI_RS05085
uniprot id: A0A087VV06
names: Subcellular Location Annotation
messages: Membrane

1341694:BINDI RS02050
gene id: 1341694:BINDI_RS02050
uniprot id: A0A087VTE1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1341694:BINDI RS01905
gene id: 1341694:BINDI_RS01905
uniprot id: A0A087VTD0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1341694:BINDI RS05225
gene id: 1341694:BINDI_RS05225
uniprot id: A0A087VVD2
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

1341694:BINDI RS05760
gene id: 1341694:BINDI_RS05760
uniprot id: A0A087VVI2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

1341694:BINDI RS02115
gene id: 1341694:BINDI_RS02115
uniprot id: A0A087VTL7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid