1330330:IX53 RS02675
gene id: 1330330:IX53_RS02675
uniprot id: A0A0G2Z5L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1330330:IX53 RS01745
gene id: 1330330:IX53_RS01745
uniprot id: A0A0G2ZD63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1330330:IX53 RS08910
gene id: 1330330:IX53_RS08910
uniprot id: A0A0G2ZGJ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1330330:IX53 RS00850
gene id: 1330330:IX53_RS00850
uniprot id: A0A0G2ZCW4
names: Similarity
messages: Belongs to the leucine-binding protein family.

1330330:IX53 RS01750
gene id: 1330330:IX53_RS01750
uniprot id: A0A0G2ZAZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1330330:IX53 RS10235
gene id: 1330330:IX53_RS10235
uniprot id: A0A0G2ZH77
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1330330:IX53 RS03790
gene id: 1330330:IX53_RS03790
uniprot id: A0A0G2ZAG7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1330330:IX53 RS09235
gene id: 1330330:IX53_RS09235
uniprot id: A0A0G2ZEK5
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1330330:IX53 RS00430
gene id: 1330330:IX53_RS00430
uniprot id: A0A0G2Z8Z3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1330330:IX53 RS03125
gene id: 1330330:IX53_RS03125
uniprot id: A0A0G2ZBQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1330330:IX53 RS00095
gene id: 1330330:IX53_RS00095
uniprot id: A0A0G2ZA88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1330330:IX53 RS10175
gene id: 1330330:IX53_RS10175
uniprot id: A0A0G2ZH72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Interacts with FtsZ.

1330330:IX53 RS02980
gene id: 1330330:IX53_RS02980
uniprot id: A0A0G2ZA52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1330330:IX53 RS10335
gene id: 1330330:IX53_RS10335
uniprot id: A0A0G2ZF43
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1330330:IX53 RS03965
gene id: 1330330:IX53_RS03965
uniprot id: A0A0G2ZE75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1330330:IX53 RS05105
gene id: 1330330:IX53_RS05105
uniprot id: A0A0G2Z6R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1330330:IX53 RS01830
gene id: 1330330:IX53_RS01830
uniprot id: A0A0G2ZF75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1330330:IX53 RS08745
gene id: 1330330:IX53_RS08745
uniprot id: A0A0G2ZGG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1330330:IX53 RS09225
gene id: 1330330:IX53_RS09225
uniprot id: A0A0G2Z8T6
names: Similarity
messages: Belongs to the UPF0597 family.

1330330:IX53 RS09605
gene id: 1330330:IX53_RS09605
uniprot id: A0A0G2Z8W8
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1330330:IX53 RS06275
gene id: 1330330:IX53_RS06275
uniprot id: A0A0G2Z7C1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1330330:IX53 RS08675
gene id: 1330330:IX53_RS08675
uniprot id: A0A0G2Z8D4
names: Similarity
messages: Belongs to the TlyA family.

1330330:IX53 RS00770
gene id: 1330330:IX53_RS00770
uniprot id: A0A0G2ZAJ2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1330330:IX53 RS03130
gene id: 1330330:IX53_RS03130
uniprot id: A0A0G2Z5U9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1330330:IX53 RS03105
gene id: 1330330:IX53_RS03105
uniprot id: A0A0G2Z5U6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1330330:IX53 RS01495
gene id: 1330330:IX53_RS01495
uniprot id: A0A0G2Z579
names: Similarity
messages: Belongs to the asp23 family.

1330330:IX53 RS01530
gene id: 1330330:IX53_RS01530
uniprot id: A0A0G2ZD27
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1330330:IX53 RS10035
gene id: 1330330:IX53_RS10035
uniprot id: A0A0G2ZH60
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1330330:IX53 RS08760
gene id: 1330330:IX53_RS08760
uniprot id: A0A0G2ZCR0
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1330330:IX53 RS08770
gene id: 1330330:IX53_RS08770
uniprot id: A0A0G2ZGG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1330330:IX53 RS00055
gene id: 1330330:IX53_RS00055
uniprot id: A0A0G2Z4K8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1330330:IX53 RS06690
gene id: 1330330:IX53_RS06690
uniprot id: A0A0G2ZDB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1330330:IX53 RS03775
gene id: 1330330:IX53_RS03775
uniprot id: A0A0G2ZC04
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1330330:IX53 RS09060
gene id: 1330330:IX53_RS09060
uniprot id: A0A0G2Z8N7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1330330:IX53 RS02400
gene id: 1330330:IX53_RS02400
uniprot id: A0A0G2Z5G5
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1330330:IX53 RS09860
gene id: 1330330:IX53_RS09860
uniprot id: A0A0G2ZEW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1330330:IX53 RS03245
gene id: 1330330:IX53_RS03245
uniprot id: A0A0G2ZBS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

1330330:IX53 RS09670
gene id: 1330330:IX53_RS09670
uniprot id: A0A0G2ZDA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1330330:IX53 RS00105
gene id: 1330330:IX53_RS00105
uniprot id: A0A0G2Z8U2
names: Similarity
messages: Belongs to the histone deacetylase family.

1330330:IX53 RS02585
gene id: 1330330:IX53_RS02585
uniprot id: A0A0G2Z5Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1330330:IX53 RS06920
gene id: 1330330:IX53_RS06920
uniprot id: A0A0G2ZFP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1330330:IX53 RS01645
gene id: 1330330:IX53_RS01645
uniprot id: A0A0G2Z596
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1330330:IX53 RS08900
gene id: 1330330:IX53_RS08900
uniprot id: A0A0G2ZCT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

1330330:IX53 RS05880
gene id: 1330330:IX53_RS05880
uniprot id: A0A0G2Z776
names: Similarity
messages: Belongs to the TPP enzyme family.

1330330:IX53 RS08905
gene id: 1330330:IX53_RS08905
uniprot id: A0A0G2Z8L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1330330:IX53 RS02025
gene id: 1330330:IX53_RS02025
uniprot id: A0A0G2Z5F2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1330330:IX53 RS05575
gene id: 1330330:IX53_RS05575
uniprot id: A0A0G2Z6Z7
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS01680
gene id: 1330330:IX53_RS01680
uniprot id: A0A0G2ZD52
names: Similarity
messages: Belongs to the AOR/FOR family.

1330330:IX53 RS05905
gene id: 1330330:IX53_RS05905
uniprot id: A0A0G2ZBF3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1330330:IX53 RS00010
gene id: 1330330:IX53_RS00010
uniprot id: A0A0G2Z4K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1330330:IX53 RS01910
gene id: 1330330:IX53_RS01910
uniprot id: A0A0G2ZB13
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1330330:IX53 RS07580
gene id: 1330330:IX53_RS07580
uniprot id: A0A0G2ZFV7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1330330:IX53 RS08740
gene id: 1330330:IX53_RS08740
uniprot id: A0A0G2Z8I9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1330330:IX53 RS02890
gene id: 1330330:IX53_RS02890
uniprot id: A0A0G2ZA42
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1330330:IX53 RS03560
gene id: 1330330:IX53_RS03560
uniprot id: A0A0G2ZE16
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1330330:IX53 RS08065
gene id: 1330330:IX53_RS08065
uniprot id: A0A0G2Z835
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1330330:IX53 RS03220
gene id: 1330330:IX53_RS03220
uniprot id: A0A0G2ZA86
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1330330:IX53 RS04490
gene id: 1330330:IX53_RS04490
uniprot id: A0A0G2ZAR8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1330330:IX53 RS00345
gene id: 1330330:IX53_RS00345
uniprot id: A0A0G2ZCQ8
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS09835
gene id: 1330330:IX53_RS09835
uniprot id: A0A0G2Z904
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1330330:IX53 RS00225
gene id: 1330330:IX53_RS00225
uniprot id: A0A0G2ZAA7
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS05245
gene id: 1330330:IX53_RS05245
uniprot id: A0A0G2ZB59
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1330330:IX53 RS04695
gene id: 1330330:IX53_RS04695
uniprot id: A0A0G2Z6N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane

1330330:IX53 RS09755
gene id: 1330330:IX53_RS09755
uniprot id: A0A0G2ZEU1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1330330:IX53 RS04110
gene id: 1330330:IX53_RS04110
uniprot id: A0A0G2Z6F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1330330:IX53 RS09955
gene id: 1330330:IX53_RS09955
uniprot id: A0A0G2ZEX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1330330:IX53 RS05125
gene id: 1330330:IX53_RS05125
uniprot id: A0A0G2ZCM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1330330:IX53 RS00815
gene id: 1330330:IX53_RS00815
uniprot id: A0A0G2Z4X3
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1330330:IX53 RS07175
gene id: 1330330:IX53_RS07175
uniprot id: A0A0G2Z7V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1330330:IX53 RS02915
gene id: 1330330:IX53_RS02915
uniprot id: A0A0G2ZBM1
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS08695
gene id: 1330330:IX53_RS08695
uniprot id: A0A0G2ZE96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1330330:IX53 RS10275
gene id: 1330330:IX53_RS10275
uniprot id: A0A0G2ZF36
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1330330:IX53 RS03595
gene id: 1330330:IX53_RS03595
uniprot id: A0A0G2ZBX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1330330:IX53 RS02865
gene id: 1330330:IX53_RS02865
uniprot id: A0A0G2ZA39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1330330:IX53 RS08240
gene id: 1330330:IX53_RS08240
uniprot id: A0A0G2Z8A6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1330330:IX53 RS04655
gene id: 1330330:IX53_RS04655
uniprot id: A0A0G2Z6J4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1330330:IX53 RS02130
gene id: 1330330:IX53_RS02130
uniprot id: A0A0G2ZB66
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1330330:IX53 RS02185
gene id: 1330330:IX53_RS02185
uniprot id: A0A0G2ZB76
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1330330:IX53 RS09590
gene id: 1330330:IX53_RS09590
uniprot id: A0A0G2Z900
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

1330330:IX53 RS04370
gene id: 1330330:IX53_RS04370
uniprot id: A0A0G2Z6J1
names: Similarity
messages: Belongs to the peptidase U62 family.

1330330:IX53 RS01580
gene id: 1330330:IX53_RS01580
uniprot id: A0A0G2Z9G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

1330330:IX53 RS02435
gene id: 1330330:IX53_RS02435
uniprot id: A0A0G2Z5M4
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1330330:IX53 RS03100
gene id: 1330330:IX53_RS03100
uniprot id: A0A0G2ZBP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1330330:IX53 RS04005
gene id: 1330330:IX53_RS04005
uniprot id: A0A0G2ZDX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1330330:IX53 RS09420
gene id: 1330330:IX53_RS09420
uniprot id: A0A0G2Z8X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1330330:IX53 RS07945
gene id: 1330330:IX53_RS07945
uniprot id: A0A0G2Z820
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1330330:IX53 RS02850
gene id: 1330330:IX53_RS02850
uniprot id: A0A0G2ZDR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1330330:IX53 RS03705
gene id: 1330330:IX53_RS03705
uniprot id: A0A0G2Z642
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1330330:IX53 RS02875
gene id: 1330330:IX53_RS02875
uniprot id: A0A0G2ZDS0
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1330330:IX53 RS05070
gene id: 1330330:IX53_RS05070
uniprot id: A0A0G2ZCL4
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS03765
gene id: 1330330:IX53_RS03765
uniprot id: A0A0G2ZE45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1330330:IX53 RS01340
gene id: 1330330:IX53_RS01340
uniprot id: A0A0G2Z9D5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

1330330:IX53 RS09700
gene id: 1330330:IX53_RS09700
uniprot id: A0A0G2Z921
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1330330:IX53 RS03745
gene id: 1330330:IX53_RS03745
uniprot id: A0A0G2ZC00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1330330:IX53 RS08550
gene id: 1330330:IX53_RS08550
uniprot id: A0A0G2ZCM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1330330:IX53 RS05355
gene id: 1330330:IX53_RS05355
uniprot id: A0A0G2Z6V8
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS09635
gene id: 1330330:IX53_RS09635
uniprot id: A0A0G2ZES0
names: Similarity
messages: Belongs to the asparaginase 1 family.

1330330:IX53 RS04885
gene id: 1330330:IX53_RS04885
uniprot id: A0A0G2ZCI4
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1330330:IX53 RS05270
gene id: 1330330:IX53_RS05270
uniprot id: A0A0G2Z6U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1330330:IX53 RS07135
gene id: 1330330:IX53_RS07135
uniprot id: A0A0G2Z7U9
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS03060
gene id: 1330330:IX53_RS03060
uniprot id: A0A0G2ZBP3
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS08990
gene id: 1330330:IX53_RS08990
uniprot id: A0A0G2ZGR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1330330:IX53 RS05225
gene id: 1330330:IX53_RS05225
uniprot id: A0A0G2Z6Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1330330:IX53 RS09810
gene id: 1330330:IX53_RS09810
uniprot id: A0A0G2Z8Z9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1330330:IX53 RS01215
gene id: 1330330:IX53_RS01215
uniprot id: A0A0G2Z4X5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1330330:IX53 RS06720
gene id: 1330330:IX53_RS06720
uniprot id: A0A0G2ZDB8
names: Similarity
messages: Belongs to the peptidase U62 family.

1330330:IX53 RS02680
gene id: 1330330:IX53_RS02680
uniprot id: A0A0G2Z9Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1330330:IX53 RS08560
gene id: 1330330:IX53_RS08560
uniprot id: A0A0G2ZGC3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1330330:IX53 RS01850
gene id: 1330330:IX53_RS01850
uniprot id: A0A0G2ZB04
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1330330:IX53 RS07365
gene id: 1330330:IX53_RS07365
uniprot id: A0A0G2ZDP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

1330330:IX53 RS09385
gene id: 1330330:IX53_RS09385
uniprot id: A0A0G2ZD60
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS02560
gene id: 1330330:IX53_RS02560
uniprot id: A0A0G2ZDI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1330330:IX53 RS01490
gene id: 1330330:IX53_RS01490
uniprot id: A0A0G2Z9F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1330330:IX53 RS10185
gene id: 1330330:IX53_RS10185
uniprot id: A0A0G2Z956
names: Similarity
messages: Belongs to the GSP E family.

1330330:IX53 RS09340
gene id: 1330330:IX53_RS09340
uniprot id: A0A0G2Z8S4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1330330:IX53 RS09240
gene id: 1330330:IX53_RS09240
uniprot id: A0A0G2Z8Q4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1330330:IX53 RS00245
gene id: 1330330:IX53_RS00245
uniprot id: A0A0G2Z4N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1330330:IX53 RS00830
gene id: 1330330:IX53_RS00830
uniprot id: A0A0G2ZAK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1330330:IX53 RS09710
gene id: 1330330:IX53_RS09710
uniprot id: A0A0G2ZH20
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1330330:IX53 RS07735
gene id: 1330330:IX53_RS07735
uniprot id: A0A0G2ZCA2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1330330:IX53 RS06105
gene id: 1330330:IX53_RS06105
uniprot id: A0A0G2Z7E2
names: Similarity
messages: Belongs to the peptidase U62 family.

1330330:IX53 RS00280
gene id: 1330330:IX53_RS00280
uniprot id: A0A0G2Z4H9
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1330330:IX53 RS07620
gene id: 1330330:IX53_RS07620
uniprot id: A0A0G2Z7X8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1330330:IX53 RS08830
gene id: 1330330:IX53_RS08830
uniprot id: A0A0G2ZEB9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1330330:IX53 RS05095
gene id: 1330330:IX53_RS05095
uniprot id: A0A0G2ZEM5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1330330:IX53 RS00840
gene id: 1330330:IX53_RS00840
uniprot id: A0A0G2Z957
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1330330:IX53 RS03540
gene id: 1330330:IX53_RS03540
uniprot id: A0A0G2ZBW9
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1330330:IX53 RS07345
gene id: 1330330:IX53_RS07345
uniprot id: A0A0G2Z7T3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1330330:IX53 RS05410
gene id: 1330330:IX53_RS05410
uniprot id: A0A0G2ZCR8
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

1330330:IX53 RS07210
gene id: 1330330:IX53_RS07210
uniprot id: A0A0G2ZFS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1330330:IX53 RS09045
gene id: 1330330:IX53_RS09045
uniprot id: A0A0G2Z8Q9
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1330330:IX53 RS09555
gene id: 1330330:IX53_RS09555
uniprot id: A0A0G2ZD86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1330330:IX53 RS00890
gene id: 1330330:IX53_RS00890
uniprot id: A0A0G2ZAK8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1330330:IX53 RS04575
gene id: 1330330:IX53_RS04575
uniprot id: A0A0G2ZAT3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1330330:IX53 RS01425
gene id: 1330330:IX53_RS01425
uniprot id: A0A0G2Z570
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1330330:IX53 RS07370
gene id: 1330330:IX53_RS07370
uniprot id: A0A0G2Z7T8
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1330330:IX53 RS02365
gene id: 1330330:IX53_RS02365
uniprot id: A0A0G2Z5G0
names: Similarity
messages: Belongs to the peptidase S9C family.

1330330:IX53 RS08570
gene id: 1330330:IX53_RS08570
uniprot id: A0A0G2Z8B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1330330:IX53 RS06905
gene id: 1330330:IX53_RS06905
uniprot id: A0A0G2Z7L6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1330330:IX53 RS06375
gene id: 1330330:IX53_RS06375
uniprot id: A0A0G2ZD76
names: Similarity
messages: Belongs to the bacterial secretin family.

1330330:IX53 RS01330
gene id: 1330330:IX53_RS01330
uniprot id: A0A0G2ZAS8
names: Subcellular Location Annotation
messages: Cytoplasm

1330330:IX53 RS03835
gene id: 1330330:IX53_RS03835
uniprot id: A0A0G2ZC09
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1330330:IX53 RS00400
gene id: 1330330:IX53_RS00400
uniprot id: A0A0G2Z8Y8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1330330:IX53 RS08640
gene id: 1330330:IX53_RS08640
uniprot id: A0A0G2ZGD9
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1330330:IX53 RS10015
gene id: 1330330:IX53_RS10015
uniprot id: A0A0G2ZEY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1330330:IX53 RS05580
gene id: 1330330:IX53_RS05580
uniprot id: A0A0G2ZBB2
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS02230
gene id: 1330330:IX53_RS02230
uniprot id: A0A0G2Z5I8
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1330330:IX53 RS03945
gene id: 1330330:IX53_RS03945
uniprot id: A0A0G2ZC21
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1330330:IX53 RS03520
gene id: 1330330:IX53_RS03520
uniprot id: A0A0G2Z611
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS08045
gene id: 1330330:IX53_RS08045
uniprot id: A0A0G2ZCE1
names: Similarity
messages: Belongs to the pyruvate kinase family.

1330330:IX53 RS07980
gene id: 1330330:IX53_RS07980
uniprot id: A0A0G2Z869
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1330330:IX53 RS08070
gene id: 1330330:IX53_RS08070
uniprot id: A0A0G2ZCE5
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS03310
gene id: 1330330:IX53_RS03310
uniprot id: A0A0G2ZAA1
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS02955
gene id: 1330330:IX53_RS02955
uniprot id: A0A0G2Z5Y4
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

1330330:IX53 RS08350
gene id: 1330330:IX53_RS08350
uniprot id: A0A0G2ZG84
names: Similarity
messages: Belongs to the peptidase M29 family.

1330330:IX53 RS10240
gene id: 1330330:IX53_RS10240
uniprot id: A0A0G2ZF32
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1330330:IX53 RS03660
gene id: 1330330:IX53_RS03660
uniprot id: A0A0G2ZBZ0
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1330330:IX53 RS09845
gene id: 1330330:IX53_RS09845
uniprot id: A0A0G2Z944
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1330330:IX53 RS02455
gene id: 1330330:IX53_RS02455
uniprot id: A0A0G2Z5H5
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1330330:IX53 RS04210
gene id: 1330330:IX53_RS04210
uniprot id: A0A0G2ZAM6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1330330:IX53 RS02730
gene id: 1330330:IX53_RS02730
uniprot id: A0A0G2Z9Z4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1330330:IX53 RS08805
gene id: 1330330:IX53_RS08805
uniprot id: A0A0G2Z8G2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1330330:IX53 RS04260
gene id: 1330330:IX53_RS04260
uniprot id: A0A0G2ZC90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1330330:IX53 RS02695
gene id: 1330330:IX53_RS02695
uniprot id: A0A0G2ZBF9
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1330330:IX53 RS03425
gene id: 1330330:IX53_RS03425
uniprot id: A0A0G2Z5Z6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1330330:IX53 RS09010
gene id: 1330330:IX53_RS09010
uniprot id: A0A0G2Z8Q5
names: Similarity
messages: Belongs to the RemA family.

1330330:IX53 RS03830
gene id: 1330330:IX53_RS03830
uniprot id: A0A0G2ZE55
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS07965
gene id: 1330330:IX53_RS07965
uniprot id: A0A0G2ZDX3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1330330:IX53 RS04645
gene id: 1330330:IX53_RS04645
uniprot id: A0A0G2ZEE2
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1330330:IX53 RS09065
gene id: 1330330:IX53_RS09065
uniprot id: A0A0G2ZCZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1330330:IX53 RS07745
gene id: 1330330:IX53_RS07745
uniprot id: A0A0G2ZFX5
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS01305
gene id: 1330330:IX53_RS01305
uniprot id: A0A0G2ZAS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1330330:IX53 RS07495
gene id: 1330330:IX53_RS07495
uniprot id: A0A0G2ZDQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1330330:IX53 RS09880
gene id: 1330330:IX53_RS09880
uniprot id: A0A0G2Z949
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1330330:IX53 RS06455
gene id: 1330330:IX53_RS06455
uniprot id: A0A0G2Z7E6
names: Similarity
messages: Belongs to the alkaline phosphatase family.

1330330:IX53 RS07915
gene id: 1330330:IX53_RS07915
uniprot id: A0A0G2ZDW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1330330:IX53 RS00155
gene id: 1330330:IX53_RS00155
uniprot id: A0A0G2Z8V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1330330:IX53 RS07185
gene id: 1330330:IX53_RS07185
uniprot id: A0A0G2ZDL7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1330330:IX53 RS08960
gene id: 1330330:IX53_RS08960
uniprot id: A0A0G2ZGK4
names: Similarity
messages: Belongs to the MEMO1 family.

1330330:IX53 RS00360
gene id: 1330330:IX53_RS00360
uniprot id: A0A0G2Z4J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1330330:IX53 RS10295
gene id: 1330330:IX53_RS10295
uniprot id: A0A0G2ZDM6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1330330:IX53 RS09450
gene id: 1330330:IX53_RS09450
uniprot id: A0A0G2Z8X7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1330330:IX53 RS07340
gene id: 1330330:IX53_RS07340
uniprot id: A0A0G2ZDP1
names: Similarity
messages: Belongs to the ArsC family.

1330330:IX53 RS02015
gene id: 1330330:IX53_RS02015
uniprot id: A0A0G2Z599
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS08865
gene id: 1330330:IX53_RS08865
uniprot id: A0A0G2Z8H2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1330330:IX53 RS09025
gene id: 1330330:IX53_RS09025
uniprot id: A0A0G2Z8N5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1330330:IX53 RS07660
gene id: 1330330:IX53_RS07660
uniprot id: A0A0G2ZC94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1330330:IX53 RS09140
gene id: 1330330:IX53_RS09140
uniprot id: A0A0G2ZEJ2
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1330330:IX53 RS02540
gene id: 1330330:IX53_RS02540
uniprot id: A0A0G2ZBD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1330330:IX53 RS05710
gene id: 1330330:IX53_RS05710
uniprot id: A0A0G2Z760
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1330330:IX53 RS04375
gene id: 1330330:IX53_RS04375
uniprot id: A0A0G2ZEC0
names: Similarity
messages: Belongs to the peptidase U62 family.

1330330:IX53 RS01940
gene id: 1330330:IX53_RS01940
uniprot id: A0A0G2ZB17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1330330:IX53 RS10105
gene id: 1330330:IX53_RS10105
uniprot id: A0A0G2Z939
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1330330:IX53 RS06225
gene id: 1330330:IX53_RS06225
uniprot id: A0A0G2Z7B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1330330:IX53 RS09055
gene id: 1330330:IX53_RS09055
uniprot id: A0A0G2ZEH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1330330:IX53 RS06165
gene id: 1330330:IX53_RS06165
uniprot id: A0A0G2ZFC8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Non-allosteric.

1330330:IX53 RS05995
gene id: 1330330:IX53_RS05995
uniprot id: A0A0G2Z7C5
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS03270
gene id: 1330330:IX53_RS03270
uniprot id: A0A0G2ZDX5
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS06740
gene id: 1330330:IX53_RS06740
uniprot id: A0A0G2Z7N9
names: Similarity
messages: Belongs to the UPF0111 family.

1330330:IX53 RS05385
gene id: 1330330:IX53_RS05385
uniprot id: A0A0G2Z6W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1330330:IX53 RS01970
gene id: 1330330:IX53_RS01970
uniprot id: A0A0G2ZB21
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1330330:IX53 RS03360
gene id: 1330330:IX53_RS03360
uniprot id: A0A0G2ZBU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1330330:IX53 RS05985
gene id: 1330330:IX53_RS05985
uniprot id: A0A0G2Z788
names: Similarity
messages: Belongs to the threonine aldolase family.

1330330:IX53 RS01950
gene id: 1330330:IX53_RS01950
uniprot id: A0A0G2Z9L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1330330:IX53 RS06715
gene id: 1330330:IX53_RS06715
uniprot id: A0A0G2ZFL3
names: Similarity
messages: Belongs to the peptidase U62 family.

1330330:IX53 RS05200
gene id: 1330330:IX53_RS05200
uniprot id: A0A0G2Z6X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1330330:IX53 RS02150
gene id: 1330330:IX53_RS02150
uniprot id: A0A0G2ZDC6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1330330:IX53 RS04280
gene id: 1330330:IX53_RS04280
uniprot id: A0A0G2ZEB1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1330330:IX53 RS01535
gene id: 1330330:IX53_RS01535
uniprot id: A0A0G2ZAW3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1330330:IX53 RS04545
gene id: 1330330:IX53_RS04545
uniprot id: A0A0G2ZAS7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1330330:IX53 RS09050
gene id: 1330330:IX53_RS09050
uniprot id: A0A0G2ZGS6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1330330:IX53 RS01995
gene id: 1330330:IX53_RS01995
uniprot id: A0A0G2ZDA1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1330330:IX53 RS05390
gene id: 1330330:IX53_RS05390
uniprot id: A0A0G2ZB83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1330330:IX53 RS08790
gene id: 1330330:IX53_RS08790
uniprot id: A0A0G2Z8J9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1330330:IX53 RS06685
gene id: 1330330:IX53_RS06685
uniprot id: A0A0G2ZFK9
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS04620
gene id: 1330330:IX53_RS04620
uniprot id: A0A0G2ZCD9
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS06110
gene id: 1330330:IX53_RS06110
uniprot id: A0A0G2ZFB9
names: Similarity
messages: Belongs to the peptidase U62 family.

1330330:IX53 RS09760
gene id: 1330330:IX53_RS09760
uniprot id: A0A0G2Z8Y9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1330330:IX53 RS03190
gene id: 1330330:IX53_RS03190
uniprot id: A0A0G2ZA79
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1330330:IX53 RS02225
gene id: 1330330:IX53_RS02225
uniprot id: A0A0G2Z9R5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1330330:IX53 RS04255
gene id: 1330330:IX53_RS04255
uniprot id: A0A0G2ZEA8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1330330:IX53 RS06410
gene id: 1330330:IX53_RS06410
uniprot id: A0A0G2ZD80
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1330330:IX53 RS02500
gene id: 1330330:IX53_RS02500
uniprot id: A0A0G2Z9V6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1330330:IX53 RS04030
gene id: 1330330:IX53_RS04030
uniprot id: A0A0G2Z6E3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1330330:IX53 RS03300
gene id: 1330330:IX53_RS03300
uniprot id: A0A0G2ZBT2
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1330330:IX53 RS02095
gene id: 1330330:IX53_RS02095
uniprot id: A0A0G2ZB61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1330330:IX53 RS03825
gene id: 1330330:IX53_RS03825
uniprot id: A0A0G2Z6B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1330330:IX53 RS06640
gene id: 1330330:IX53_RS06640
uniprot id: A0A0G2Z7H3
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS00030
gene id: 1330330:IX53_RS00030
uniprot id: A0A0G2Z4E9
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1330330:IX53 RS06940
gene id: 1330330:IX53_RS06940
uniprot id: A0A0G2Z7S0
names: Similarity
messages: Belongs to the class-I fumarase family.

1330330:IX53 RS07120
gene id: 1330330:IX53_RS07120
uniprot id: A0A0G2ZDK6
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

1330330:IX53 RS03355
gene id: 1330330:IX53_RS03355
uniprot id: A0A0G2ZDY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1330330:IX53 RS03305
gene id: 1330330:IX53_RS03305
uniprot id: A0A0G2Z5X5
names: Similarity
messages: Belongs to the UPF0047 family.

1330330:IX53 RS03880
gene id: 1330330:IX53_RS03880
uniprot id: A0A0G2ZAI2
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1330330:IX53 RS09465
gene id: 1330330:IX53_RS09465
uniprot id: A0A0G2Z8U4
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS06500
gene id: 1330330:IX53_RS06500
uniprot id: A0A0G2Z7K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1330330:IX53 RS09175
gene id: 1330330:IX53_RS09175
uniprot id: A0A0G2ZEJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1330330:IX53 RS10040
gene id: 1330330:IX53_RS10040
uniprot id: A0A0G2ZEY9
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1330330:IX53 RS04015
gene id: 1330330:IX53_RS04015
uniprot id: A0A0G2ZC28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1330330:IX53 RS09855
gene id: 1330330:IX53_RS09855
uniprot id: A0A0G2ZH41
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1330330:IX53 RS08535
gene id: 1330330:IX53_RS08535
uniprot id: A0A0G2ZGB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1330330:IX53 RS09000
gene id: 1330330:IX53_RS09000
uniprot id: A0A0G2Z8N3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1330330:IX53 RS09485
gene id: 1330330:IX53_RS09485
uniprot id: A0A0G2ZEP6
names: Similarity
messages: Belongs to the UPF0047 family.

1330330:IX53 RS11100
gene id: 1330330:IX53_RS11100
uniprot id: A0A0G2Z5D1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1330330:IX53 RS07270
gene id: 1330330:IX53_RS07270
uniprot id: A0A0G2Z7X0
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

1330330:IX53 RS09100
gene id: 1330330:IX53_RS09100
uniprot id: A0A0G2ZGT4
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1330330:IX53 RS04265
gene id: 1330330:IX53_RS04265
uniprot id: A0A0G2Z6C7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1330330:IX53 RS00190
gene id: 1330330:IX53_RS00190
uniprot id: A0A0G2Z8V7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1330330:IX53 RS00100
gene id: 1330330:IX53_RS00100
uniprot id: A0A0G2Z4F6
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1330330:IX53 RS07970
gene id: 1330330:IX53_RS07970
uniprot id: A0A0G2Z824
names: Similarity
messages: Belongs to the DapA family.

1330330:IX53 RS09185
gene id: 1330330:IX53_RS09185
uniprot id: A0A0G2ZD09
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1330330:IX53 RS04070
gene id: 1330330:IX53_RS04070
uniprot id: A0A0G2Z6E9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1330330:IX53 RS00090
gene id: 1330330:IX53_RS00090
uniprot id: A0A0G2ZCK3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1330330:IX53 RS01260
gene id: 1330330:IX53_RS01260
uniprot id: A0A0G2Z542
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

1330330:IX53 RS08835
gene id: 1330330:IX53_RS08835
uniprot id: A0A0G2Z9W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1330330:IX53 RS01455
gene id: 1330330:IX53_RS01455
uniprot id: A0A0G2Z574
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1330330:IX53 RS08685
gene id: 1330330:IX53_RS08685
uniprot id: A0A0G2Z8I1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1330330:IX53 RS02665
gene id: 1330330:IX53_RS02665
uniprot id: A0A0G2ZDK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1330330:IX53 RS06810
gene id: 1330330:IX53_RS06810
uniprot id: A0A0G2Z7K1
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS08145
gene id: 1330330:IX53_RS08145
uniprot id: A0A0G2ZG48
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1330330:IX53 RS09990
gene id: 1330330:IX53_RS09990
uniprot id: A0A0G2ZDI1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1330330:IX53 RS06520
gene id: 1330330:IX53_RS06520
uniprot id: A0A0G2ZBS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1330330:IX53 RS01520
gene id: 1330330:IX53_RS01520
uniprot id: A0A0G2Z9G0
names: Similarity
messages: Belongs to the asp23 family.

1330330:IX53 RS03875
gene id: 1330330:IX53_RS03875
uniprot id: A0A0G2Z667
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1330330:IX53 RS09775
gene id: 1330330:IX53_RS09775
uniprot id: A0A0G2ZH29
names: Similarity
messages: Belongs to the CTP synthase family.

1330330:IX53 RS02145
gene id: 1330330:IX53_RS02145
uniprot id: A0A0G2Z5H2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1330330:IX53 RS07805
gene id: 1330330:IX53_RS07805
uniprot id: A0A0G2ZFY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1330330:IX53 RS04295
gene id: 1330330:IX53_RS04295
uniprot id: A0A0G2Z6D3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1330330:IX53 RS08080
gene id: 1330330:IX53_RS08080
uniprot id: A0A0G2ZG37
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

1330330:IX53 RS08875
gene id: 1330330:IX53_RS08875
uniprot id: A0A0G2Z8L2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1330330:IX53 RS04910
gene id: 1330330:IX53_RS04910
uniprot id: A0A0G2ZEJ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

1330330:IX53 RS08720
gene id: 1330330:IX53_RS08720
uniprot id: A0A0G2ZEA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1330330:IX53 RS02190
gene id: 1330330:IX53_RS02190
uniprot id: A0A0G2Z5C5
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1330330:IX53 RS09890
gene id: 1330330:IX53_RS09890
uniprot id: A0A0G2ZEW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1330330:IX53 RS06890
gene id: 1330330:IX53_RS06890
uniprot id: A0A0G2ZFN9
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

1330330:IX53 RS03110
gene id: 1330330:IX53_RS03110
uniprot id: A0A0G2ZA67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1330330:IX53 RS05210
gene id: 1330330:IX53_RS05210
uniprot id: A0A0G2ZCN9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1330330:IX53 RS03015
gene id: 1330330:IX53_RS03015
uniprot id: A0A0G2ZA56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1330330:IX53 RS08055
gene id: 1330330:IX53_RS08055
uniprot id: A0A0G2ZG32
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS09180
gene id: 1330330:IX53_RS09180
uniprot id: A0A0G2Z8P6
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1330330:IX53 RS08810
gene id: 1330330:IX53_RS08810
uniprot id: A0A0G2ZCR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1330330:IX53 RS03695
gene id: 1330330:IX53_RS03695
uniprot id: A0A0G2ZE35
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1330330:IX53 RS08855
gene id: 1330330:IX53_RS08855
uniprot id: A0A0G2ZGI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1330330:IX53 RS04770
gene id: 1330330:IX53_RS04770
uniprot id: A0A0G2ZCG3
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

1330330:IX53 RS02465
gene id: 1330330:IX53_RS02465
uniprot id: A0A0G2Z5N0
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1330330:IX53 RS04025
gene id: 1330330:IX53_RS04025
uniprot id: A0A0G2ZAJ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1330330:IX53 RS06270
gene id: 1330330:IX53_RS06270
uniprot id: A0A0G2ZD61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1330330:IX53 RS08860
gene id: 1330330:IX53_RS08860
uniprot id: A0A0G2ZEC3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1330330:IX53 RS02200
gene id: 1330330:IX53_RS02200
uniprot id: A0A0G2Z5I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1330330:IX53 RS04980
gene id: 1330330:IX53_RS04980
uniprot id: A0A0G2Z6N7
names: Similarity
messages: Belongs to the acylphosphatase family.

1330330:IX53 RS04160
gene id: 1330330:IX53_RS04160
uniprot id: A0A0G2Z6A9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1330330:IX53 RS07095
gene id: 1330330:IX53_RS07095
uniprot id: A0A0G2ZC14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

1330330:IX53 RS01210
gene id: 1330330:IX53_RS01210
uniprot id: A0A0G2ZAR0
names: Similarity
messages: Belongs to the citrate synthase family.

1330330:IX53 RS04570
gene id: 1330330:IX53_RS04570
uniprot id: A0A0G2Z6I0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1330330:IX53 RS06070
gene id: 1330330:IX53_RS06070
uniprot id: A0A0G2Z794
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1330330:IX53 RS05990
gene id: 1330330:IX53_RS05990
uniprot id: A0A0G2ZBK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1330330:IX53 RS07075
gene id: 1330330:IX53_RS07075
uniprot id: A0A0G2Z7T9
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS04020
gene id: 1330330:IX53_RS04020
uniprot id: A0A0G2Z686
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1330330:IX53 RS05695
gene id: 1330330:IX53_RS05695
uniprot id: A0A0G2ZCV3
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1330330:IX53 RS05425
gene id: 1330330:IX53_RS05425
uniprot id: A0A0G2ZB88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1330330:IX53 RS07160
gene id: 1330330:IX53_RS07160
uniprot id: A0A0G2ZC25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1330330:IX53 RS08840
gene id: 1330330:IX53_RS08840
uniprot id: A0A0G2Z8G7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1330330:IX53 RS03035
gene id: 1330330:IX53_RS03035
uniprot id: A0A0G2Z5U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1330330:IX53 RS08825
gene id: 1330330:IX53_RS08825
uniprot id: A0A0G2ZGH6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1330330:IX53 RS09785
gene id: 1330330:IX53_RS09785
uniprot id: A0A0G2Z8Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1330330:IX53 RS02570
gene id: 1330330:IX53_RS02570
uniprot id: A0A0G2Z5J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1330330:IX53 RS01290
gene id: 1330330:IX53_RS01290
uniprot id: A0A0G2Z548
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1330330:IX53 RS03065
gene id: 1330330:IX53_RS03065
uniprot id: A0A0G2Z5U3
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS05335
gene id: 1330330:IX53_RS05335
uniprot id: A0A0G2ZB73
names: Similarity
messages: Belongs to the FGGY kinase family.

1330330:IX53 RS07935
gene id: 1330330:IX53_RS07935
uniprot id: A0A0G2ZG10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1330330:IX53 RS03000
gene id: 1330330:IX53_RS03000
uniprot id: A0A0G2ZDU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1330330:IX53 RS01465
gene id: 1330330:IX53_RS01465
uniprot id: A0A0G2ZAV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1330330:IX53 RS03700
gene id: 1330330:IX53_RS03700
uniprot id: A0A0G2ZBZ5
names: Similarity
messages: Belongs to the GSP E family.

1330330:IX53 RS09750
gene id: 1330330:IX53_RS09750
uniprot id: A0A0G2ZH25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1330330:IX53 RS09685
gene id: 1330330:IX53_RS09685
uniprot id: A0A0G2ZET0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1330330:IX53 RS04550
gene id: 1330330:IX53_RS04550
uniprot id: A0A0G2Z6L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1330330:IX53 RS09915
gene id: 1330330:IX53_RS09915
uniprot id: A0A0G2ZH47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

1330330:IX53 RS09080
gene id: 1330330:IX53_RS09080
uniprot id: A0A0G2ZEI2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1330330:IX53 RS06800
gene id: 1330330:IX53_RS06800
uniprot id: A0A0G2ZFM7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1330330:IX53 RS07230
gene id: 1330330:IX53_RS07230
uniprot id: A0A0G2ZC32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

1330330:IX53 RS03960
gene id: 1330330:IX53_RS03960
uniprot id: A0A0G2Z6D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1330330:IX53 RS00395
gene id: 1330330:IX53_RS00395
uniprot id: A0A0G2Z4J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1330330:IX53 RS02255
gene id: 1330330:IX53_RS02255
uniprot id: A0A0G2Z9S0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1330330:IX53 RS03910
gene id: 1330330:IX53_RS03910
uniprot id: A0A0G2Z672
names: Similarity
messages: Belongs to the RecJ family.

1330330:IX53 RS07615
gene id: 1330330:IX53_RS07615
uniprot id: A0A0G2ZDR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1330330:IX53 RS02135
gene id: 1330330:IX53_RS02135
uniprot id: A0A0G2Z5B6
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1330330:IX53 RS03795
gene id: 1330330:IX53_RS03795
uniprot id: A0A0G2Z6B1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1330330:IX53 RS02685
gene id: 1330330:IX53_RS02685
uniprot id: A0A0G2Z5R5
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1330330:IX53 RS08735
gene id: 1330330:IX53_RS08735
uniprot id: A0A0G2ZCQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1330330:IX53 RS06795
gene id: 1330330:IX53_RS06795
uniprot id: A0A0G2Z7P8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1330330:IX53 RS06010
gene id: 1330330:IX53_RS06010
uniprot id: A0A0G2Z790
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1330330:IX53 RS03260
gene id: 1330330:IX53_RS03260
uniprot id: A0A0G2ZA91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1330330:IX53 RS02315
gene id: 1330330:IX53_RS02315
uniprot id: A0A0G2Z9T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1330330:IX53 RS03175
gene id: 1330330:IX53_RS03175
uniprot id: A0A0G2ZDW3
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS03995
gene id: 1330330:IX53_RS03995
uniprot id: A0A0G2Z6D9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1330330:IX53 RS07715
gene id: 1330330:IX53_RS07715
uniprot id: A0A0G2ZFX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1330330:IX53 RS10330
gene id: 1330330:IX53_RS10330
uniprot id: A0A0G2ZH85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1330330:IX53 RS06510
gene id: 1330330:IX53_RS06510
uniprot id: A0A0G2ZD91
names: Similarity
messages: Belongs to the glycosyltransferase 1 family.

1330330:IX53 RS09525
gene id: 1330330:IX53_RS09525
uniprot id: A0A0G2Z8V4
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS09625
gene id: 1330330:IX53_RS09625
uniprot id: A0A0G2ZH06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1330330:IX53 RS05165
gene id: 1330330:IX53_RS05165
uniprot id: A0A0G2ZB23
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

1330330:IX53 RS06600
gene id: 1330330:IX53_RS06600
uniprot id: A0A0G2ZFJ5
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS00845
gene id: 1330330:IX53_RS00845
uniprot id: A0A0G2Z4X8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1330330:IX53 RS05160
gene id: 1330330:IX53_RS05160
uniprot id: A0A0G2Z6S0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1330330:IX53 RS00800
gene id: 1330330:IX53_RS00800
uniprot id: A0A0G2Z4R3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1330330:IX53 RS02140
gene id: 1330330:IX53_RS02140
uniprot id: A0A0G2Z9Q0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1330330:IX53 RS06885
gene id: 1330330:IX53_RS06885
uniprot id: A0A0G2Z7R2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1330330:IX53 RS08540
gene id: 1330330:IX53_RS08540
uniprot id: A0A0G2ZE64
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1330330:IX53 RS07225
gene id: 1330330:IX53_RS07225
uniprot id: A0A0G2Z7R4
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS03205
gene id: 1330330:IX53_RS03205
uniprot id: A0A0G2ZBR7
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1330330:IX53 RS02050
gene id: 1330330:IX53_RS02050
uniprot id: A0A0G2Z9N4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1330330:IX53 RS10365
gene id: 1330330:IX53_RS10365
uniprot id: A0A0G2ZF47
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1330330:IX53 RS03020
gene id: 1330330:IX53_RS03020
uniprot id: A0A0G2Z5Z7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1330330:IX53 RS00385
gene id: 1330330:IX53_RS00385
uniprot id: A0A0G2ZCR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

1330330:IX53 RS04960
gene id: 1330330:IX53_RS04960
uniprot id: A0A0G2ZAZ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1330330:IX53 RS09770
gene id: 1330330:IX53_RS09770
uniprot id: A0A0G2Z929
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1330330:IX53 RS03390
gene id: 1330330:IX53_RS03390
uniprot id: A0A0G2ZBU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1330330:IX53 RS00870
gene id: 1330330:IX53_RS00870
uniprot id: A0A0G2Z4Y3
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS06840
gene id: 1330330:IX53_RS06840
uniprot id: A0A0G2Z7K7
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

1330330:IX53 RS08030
gene id: 1330330:IX53_RS08030
uniprot id: A0A0G2ZG26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1330330:IX53 RS05290
gene id: 1330330:IX53_RS05290
uniprot id: A0A0G2ZCQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

1330330:IX53 RS08315
gene id: 1330330:IX53_RS08315
uniprot id: A0A0G2ZCI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1330330:IX53 RS06495
gene id: 1330330:IX53_RS06495
uniprot id: A0A0G2ZBR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1330330:IX53 RS06790
gene id: 1330330:IX53_RS06790
uniprot id: A0A0G2ZBW8
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS09805
gene id: 1330330:IX53_RS09805
uniprot id: A0A0G2ZEV1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1330330:IX53 RS04555
gene id: 1330330:IX53_RS04555
uniprot id: A0A0G2ZED6
names: Similarity
messages: Belongs to the pyruvate kinase family.

1330330:IX53 RS03600
gene id: 1330330:IX53_RS03600
uniprot id: A0A0G2Z627
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1330330:IX53 RS03980
gene id: 1330330:IX53_RS03980
uniprot id: A0A0G2Z681
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

1330330:IX53 RS02855
gene id: 1330330:IX53_RS02855
uniprot id: A0A0G2ZBL1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1330330:IX53 RS00070
gene id: 1330330:IX53_RS00070
uniprot id: A0A0G2ZA83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1330330:IX53 RS02355
gene id: 1330330:IX53_RS02355
uniprot id: A0A0G2ZDG1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1330330:IX53 RS10165
gene id: 1330330:IX53_RS10165
uniprot id: A0A0G2ZDK7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1330330:IX53 RS07565
gene id: 1330330:IX53_RS07565
uniprot id: A0A0G2Z7W7
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1330330:IX53 RS08690
gene id: 1330330:IX53_RS08690
uniprot id: A0A0G2ZGF0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1330330:IX53 RS03430
gene id: 1330330:IX53_RS03430
uniprot id: A0A0G2ZAC0
names: Subcellular Location Annotation
messages: Cytoplasm

1330330:IX53 RS08850
gene id: 1330330:IX53_RS08850
uniprot id: A0A0G2Z8K8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1330330:IX53 RS05535
gene id: 1330330:IX53_RS05535
uniprot id: A0A0G2ZEV8
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS08730
gene id: 1330330:IX53_RS08730
uniprot id: A0A0G2Z8E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1330330:IX53 RS06655
gene id: 1330330:IX53_RS06655
uniprot id: A0A0G2ZFK5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1330330:IX53 RS09470
gene id: 1330330:IX53_RS09470
uniprot id: A0A0G2ZD75
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1330330:IX53 RS04245
gene id: 1330330:IX53_RS04245
uniprot id: A0A0G2ZAN1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1330330:IX53 RS03275
gene id: 1330330:IX53_RS03275
uniprot id: A0A0G2ZBS7
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1330330:IX53 RS08655
gene id: 1330330:IX53_RS08655
uniprot id: A0A0G2ZCP4
names: Similarity
messages: Belongs to the UPF0102 family.

1330330:IX53 RS09615
gene id: 1330330:IX53_RS09615
uniprot id: A0A0G2ZD94
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1330330:IX53 RS01505
gene id: 1330330:IX53_RS01505
uniprot id: A0A0G2ZAV9
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1330330:IX53 RS08650
gene id: 1330330:IX53_RS08650
uniprot id: A0A0G2Z8C8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1330330:IX53 RS02495
gene id: 1330330:IX53_RS02495
uniprot id: A0A0G2Z5I0
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1330330:IX53 RS11005
gene id: 1330330:IX53_RS11005
uniprot id: A0A0G2ZDS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1330330:IX53 RS01360
gene id: 1330330:IX53_RS01360
uniprot id: A0A0G2Z500
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1330330:IX53 RS10100
gene id: 1330330:IX53_RS10100
uniprot id: A0A0G2ZEZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1330330:IX53 RS08170
gene id: 1330330:IX53_RS08170
uniprot id: A0A0G2Z9N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1330330:IX53 RS01445
gene id: 1330330:IX53_RS01445
uniprot id: A0A0G2Z9F2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

1330330:IX53 RS04175
gene id: 1330330:IX53_RS04175
uniprot id: A0A0G2ZE98
names: Similarity
messages: Belongs to the carbamate kinase family.

1330330:IX53 RS06955
gene id: 1330330:IX53_RS06955
uniprot id: A0A0G2Z7M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1330330:IX53 RS02460
gene id: 1330330:IX53_RS02460
uniprot id: A0A0G2Z9V1
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1330330:IX53 RS06780
gene id: 1330330:IX53_RS06780
uniprot id: A0A0G2ZDC9
names: Function
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1330330:IX53 RS07090
gene id: 1330330:IX53_RS07090
uniprot id: A0A0G2Z7P6
names: Similarity
messages: Belongs to the peptidase S41A family.

1330330:IX53 RS07645
gene id: 1330330:IX53_RS07645
uniprot id: A0A0G2ZDR7
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS05675
gene id: 1330330:IX53_RS05675
uniprot id: A0A0G2ZBC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1330330:IX53 RS09435
gene id: 1330330:IX53_RS09435
uniprot id: A0A0G2ZEN7
names: Similarity
messages: Belongs to the Skp family.

1330330:IX53 RS04630
gene id: 1330330:IX53_RS04630
uniprot id: A0A0G2ZAU3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1330330:IX53 RS06120
gene id: 1330330:IX53_RS06120
uniprot id: A0A0G2Z7A2
names: Similarity
messages: Belongs to the peptidase C69 family.

1330330:IX53 RS01870
gene id: 1330330:IX53_RS01870
uniprot id: A0A0G2Z5C7
names: Similarity
messages: Belongs to the YggT family.

1330330:IX53 RS05950
gene id: 1330330:IX53_RS05950
uniprot id: A0A0G2ZD17
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS00300
gene id: 1330330:IX53_RS00300
uniprot id: A0A0G2ZAB7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1330330:IX53 RS10180
gene id: 1330330:IX53_RS10180
uniprot id: A0A0G2ZF24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1330330:IX53 RS08630
gene id: 1330330:IX53_RS08630
uniprot id: A0A0G2ZCP0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1330330:IX53 RS09160
gene id: 1330330:IX53_RS09160
uniprot id: A0A0G2ZD06
names: Similarity
messages: Belongs to the peptidase U62 family.

1330330:IX53 RS03115
gene id: 1330330:IX53_RS03115
uniprot id: A0A0G2Z612
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1330330:IX53 RS02545
gene id: 1330330:IX53_RS02545
uniprot id: A0A0G2Z5J0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1330330:IX53 RS10225
gene id: 1330330:IX53_RS10225
uniprot id: A0A0G2ZDL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1330330:IX53 RS03085
gene id: 1330330:IX53_RS03085
uniprot id: A0A0G2Z606
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1330330:IX53 RS07335
gene id: 1330330:IX53_RS07335
uniprot id: A0A0G2ZFT6
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

1330330:IX53 RS00075
gene id: 1330330:IX53_RS00075
uniprot id: A0A0G2Z4F3
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS10360
gene id: 1330330:IX53_RS10360
uniprot id: A0A0G2ZH87
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1330330:IX53 RS09430
gene id: 1330330:IX53_RS09430
uniprot id: A0A0G2ZGX8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1330330:IX53 RS08660
gene id: 1330330:IX53_RS08660
uniprot id: A0A0G2Z8H6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1330330:IX53 RS06615
gene id: 1330330:IX53_RS06615
uniprot id: A0A0G2Z7G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1330330:IX53 RS06985
gene id: 1330330:IX53_RS06985
uniprot id: A0A0G2Z9L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1330330:IX53 RS05605
gene id: 1330330:IX53_RS05605
uniprot id: A0A0G2ZBB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1330330:IX53 RS08320
gene id: 1330330:IX53_RS08320
uniprot id: A0A0G2Z8B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1330330:IX53 RS08955
gene id: 1330330:IX53_RS08955
uniprot id: A0A0G2Z8M4
names: Similarity
messages: Belongs to the bacterial secretin family.

1330330:IX53 RS09960
gene id: 1330330:IX53_RS09960
uniprot id: A0A0G2Z923
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1330330:IX53 RS05570
gene id: 1330330:IX53_RS05570
uniprot id: A0A0G2ZCT9
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS02375
gene id: 1330330:IX53_RS02375
uniprot id: A0A0G2Z9T7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

1330330:IX53 RS04010
gene id: 1330330:IX53_RS04010
uniprot id: A0A0G2ZE80
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1330330:IX53 RS01250
gene id: 1330330:IX53_RS01250
uniprot id: A0A0G2Z4Y0
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

1330330:IX53 RS02440
gene id: 1330330:IX53_RS02440
uniprot id: A0A0G2ZDH1
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

1330330:IX53 RS04320
gene id: 1330330:IX53_RS04320
uniprot id: A0A0G2ZC99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1330330:IX53 RS08895
gene id: 1330330:IX53_RS08895
uniprot id: A0A0G2Z8H8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1330330:IX53 RS05350
gene id: 1330330:IX53_RS05350
uniprot id: A0A0G2ZCR1
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1330330:IX53 RS00140
gene id: 1330330:IX53_RS00140
uniprot id: A0A0G2ZCL3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

1330330:IX53 RS01945
gene id: 1330330:IX53_RS01945
uniprot id: A0A0G2Z591
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1330330:IX53 RS02175
gene id: 1330330:IX53_RS02175
uniprot id: A0A0G2Z5H8
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

1330330:IX53 RS02530
gene id: 1330330:IX53_RS02530
uniprot id: A0A0G2Z5P2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1330330:IX53 RS08220
gene id: 1330330:IX53_RS08220
uniprot id: A0A0G2ZG60
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1330330:IX53 RS08670
gene id: 1330330:IX53_RS08670
uniprot id: A0A0G2ZE91
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1330330:IX53 RS00170
gene id: 1330330:IX53_RS00170
uniprot id: A0A0G2ZAA2
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

1330330:IX53 RS04290
gene id: 1330330:IX53_RS04290
uniprot id: A0A0G2ZC95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XseA family.
messages: Cytoplasm

1330330:IX53 RS09975
gene id: 1330330:IX53_RS09975
uniprot id: A0A0G2ZH54
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1330330:IX53 RS05255
gene id: 1330330:IX53_RS05255
uniprot id: A0A0G2Z6Y2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1330330:IX53 RS03890
gene id: 1330330:IX53_RS03890
uniprot id: A0A0G2Z6C6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1330330:IX53 RS08555
gene id: 1330330:IX53_RS08555
uniprot id: A0A0G2Z8F6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1330330:IX53 RS05215
gene id: 1330330:IX53_RS05215
uniprot id: A0A0G2Z6T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1330330:IX53 RS02595
gene id: 1330330:IX53_RS02595
uniprot id: A0A0G2ZBE6
names: Similarity
messages: Belongs to the peptidase M16 family.

1330330:IX53 RS03810
gene id: 1330330:IX53_RS03810
uniprot id: A0A0G2ZC07
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1330330:IX53 RS08475
gene id: 1330330:IX53_RS08475
uniprot id: A0A0G2ZGA7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1330330:IX53 RS08385
gene id: 1330330:IX53_RS08385
uniprot id: A0A0G2Z883
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1330330:IX53 RS09650
gene id: 1330330:IX53_RS09650
uniprot id: A0A0G2Z911
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1330330:IX53 RS10340
gene id: 1330330:IX53_RS10340
uniprot id: A0A0G2Z979
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1330330:IX53 RS08230
gene id: 1330330:IX53_RS08230
uniprot id: A0A0G2Z857
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1330330:IX53 RS03575
gene id: 1330330:IX53_RS03575
uniprot id: A0A0G2ZAE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1330330:IX53 RS03010
gene id: 1330330:IX53_RS03010
uniprot id: A0A0G2Z5T9
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1330330:IX53 RS09550
gene id: 1330330:IX53_RS09550
uniprot id: A0A0G2Z8V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1330330:IX53 RS01235
gene id: 1330330:IX53_RS01235
uniprot id: A0A0G2Z537
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS05555
gene id: 1330330:IX53_RS05555
uniprot id: A0A0G2Z733
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1330330:IX53 RS08360
gene id: 1330330:IX53_RS08360
uniprot id: A0A0G2Z878
names: Cofactor
messages: Binds 2 irons ions per subunit via 4 cysteine residues per iron.

1330330:IX53 RS02245
gene id: 1330330:IX53_RS02245
uniprot id: A0A0G2ZB87
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1330330:IX53 RS02195
gene id: 1330330:IX53_RS02195
uniprot id: A0A0G2Z9R0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1330330:IX53 RS01610
gene id: 1330330:IX53_RS01610
uniprot id: A0A0G2Z9H4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1330330:IX53 RS02125
gene id: 1330330:IX53_RS02125
uniprot id: A0A0G2ZDC1
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1330330:IX53 RS08800
gene id: 1330330:IX53_RS08800
uniprot id: A0A0G2ZEB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1330330:IX53 RS05670
gene id: 1330330:IX53_RS05670
uniprot id: A0A0G2Z712
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1330330:IX53 RS05610
gene id: 1330330:IX53_RS05610
uniprot id: A0A0G2Z744
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1330330:IX53 RS02310
gene id: 1330330:IX53_RS02310
uniprot id: A0A0G2Z5F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1330330:IX53 RS09075
gene id: 1330330:IX53_RS09075
uniprot id: A0A0G2ZGT1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1330330:IX53 RS08530
gene id: 1330330:IX53_RS08530
uniprot id: A0A0G2ZHT5
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1330330:IX53 RS06180
gene id: 1330330:IX53_RS06180
uniprot id: A0A0G2Z7B0
names: Similarity
messages: Belongs to the DEAD box helicase family.

1330330:IX53 RS04680
gene id: 1330330:IX53_RS04680
uniprot id: A0A0G2ZCE9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1330330:IX53 RS02840
gene id: 1330330:IX53_RS02840
uniprot id: A0A0G2ZA07
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1330330:IX53 RS08245
gene id: 1330330:IX53_RS08245
uniprot id: A0A0G2ZG66
names: Similarity
messages: Belongs to the fabD family.

1330330:IX53 RS02555
gene id: 1330330:IX53_RS02555
uniprot id: A0A0G2Z5P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1330330:IX53 RS03565
gene id: 1330330:IX53_RS03565
uniprot id: A0A0G2ZBX3
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS04275
gene id: 1330330:IX53_RS04275
uniprot id: A0A0G2Z6H5
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1330330:IX53 RS08645
gene id: 1330330:IX53_RS08645
uniprot id: A0A0G2ZE86
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

1330330:IX53 RS08325
gene id: 1330330:IX53_RS08325
uniprot id: A0A0G2ZG77
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1330330:IX53 RS05800
gene id: 1330330:IX53_RS05800
uniprot id: A0A0G2ZCW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1330330:IX53 RS01540
gene id: 1330330:IX53_RS01540
uniprot id: A0A0G2Z531
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1330330:IX53 RS06815
gene id: 1330330:IX53_RS06815
uniprot id: A0A0G2ZBX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1330330:IX53 RS01285
gene id: 1330330:IX53_RS01285
uniprot id: A0A0G2Z9C4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1330330:IX53 RS03165
gene id: 1330330:IX53_RS03165
uniprot id: A0A0G2ZA75
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1330330:IX53 RS00230
gene id: 1330330:IX53_RS00230
uniprot id: A0A0G2Z4H3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1330330:IX53 RS03935
gene id: 1330330:IX53_RS03935
uniprot id: A0A0G2Z6D2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1330330:IX53 RS04685
gene id: 1330330:IX53_RS04685
uniprot id: A0A0G2Z6J9
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1330330:IX53 RS05340
gene id: 1330330:IX53_RS05340
uniprot id: A0A0G2Z6Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1330330:IX53 RS00005
gene id: 1330330:IX53_RS00005
uniprot id: A0A0G2Z984
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1330330:IX53 RS06990
gene id: 1330330:IX53_RS06990
uniprot id: A0A0G2ZC03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1330330:IX53 RS08755
gene id: 1330330:IX53_RS08755
uniprot id: A0A0G2Z8F0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1330330:IX53 RS01800
gene id: 1330330:IX53_RS01800
uniprot id: A0A0G2Z9J6
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

1330330:IX53 RS02860
gene id: 1330330:IX53_RS02860
uniprot id: A0A0G2Z5T0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1330330:IX53 RS07555
gene id: 1330330:IX53_RS07555
uniprot id: A0A0G2ZFV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1330330:IX53 RS03120
gene id: 1330330:IX53_RS03120
uniprot id: A0A0G2ZDV5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1330330:IX53 RS03975
gene id: 1330330:IX53_RS03975
uniprot id: A0A0G2ZC24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1330330:IX53 RS01545
gene id: 1330330:IX53_RS01545
uniprot id: A0A0G2Z9G5
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS03725
gene id: 1330330:IX53_RS03725
uniprot id: A0A0G2ZE41
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

1330330:IX53 RS03250
gene id: 1330330:IX53_RS03250
uniprot id: A0A0G2Z5W5
names: Similarity
messages: Belongs to the peptidase S1C family.

1330330:IX53 RS08715
gene id: 1330330:IX53_RS08715
uniprot id: A0A0G2ZGF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1330330:IX53 RS09900
gene id: 1330330:IX53_RS09900
uniprot id: A0A0G2Z9X6
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1330330:IX53 RS02490
gene id: 1330330:IX53_RS02490
uniprot id: A0A0G2ZDU1
names: Similarity
messages: Belongs to the glutamine synthetase family.

1330330:IX53 RS02820
gene id: 1330330:IX53_RS02820
uniprot id: A0A0G2Z5S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1330330:IX53 RS00195
gene id: 1330330:IX53_RS00195
uniprot id: A0A0G2Z4N1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1330330:IX53 RS09495
gene id: 1330330:IX53_RS09495
uniprot id: A0A0G2ZD79
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS09945
gene id: 1330330:IX53_RS09945
uniprot id: A0A0G2Z961
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1330330:IX53 RS04475
gene id: 1330330:IX53_RS04475
uniprot id: A0A0G2ZEC8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1330330:IX53 RS08040
gene id: 1330330:IX53_RS08040
uniprot id: A0A0G2Z831
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1330330:IX53 RS02290
gene id: 1330330:IX53_RS02290
uniprot id: A0A0G2Z5J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1330330:IX53 RS04325
gene id: 1330330:IX53_RS04325
uniprot id: A0A0G2Z6D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1330330:IX53 RS02085
gene id: 1330330:IX53_RS02085
uniprot id: A0A0G2Z5G3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1330330:IX53 RS01015
gene id: 1330330:IX53_RS01015
uniprot id: A0A0G2ZAM8
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1330330:IX53 RS10010
gene id: 1330330:IX53_RS10010
uniprot id: A0A0G2Z9R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1330330:IX53 RS08465
gene id: 1330330:IX53_RS08465
uniprot id: A0A0G2ZCL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1330330:IX53 RS07245
gene id: 1330330:IX53_RS07245
uniprot id: A0A0G2ZDM7
names: Similarity
messages: Belongs to the ETF-QO/FixC family.

1330330:IX53 RS02215
gene id: 1330330:IX53_RS02215
uniprot id: A0A0G2Z5D3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1330330:IX53 RS06950
gene id: 1330330:IX53_RS06950
uniprot id: A0A0G2ZDI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1330330:IX53 RS00500
gene id: 1330330:IX53_RS00500
uniprot id: A0A0G2ZAE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1330330:IX53 RS01935
gene id: 1330330:IX53_RS01935
uniprot id: A0A0G2ZD92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1330330:IX53 RS05235
gene id: 1330330:IX53_RS05235
uniprot id: A0A0G2ZCP3
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1330330:IX53 RS07575
gene id: 1330330:IX53_RS07575
uniprot id: A0A0G2Z810
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1330330:IX53 RS09645
gene id: 1330330:IX53_RS09645
uniprot id: A0A0G2ZD99
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1330330:IX53 RS08725
gene id: 1330330:IX53_RS08725
uniprot id: A0A0G2Z9P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1330330:IX53 RS10355
gene id: 1330330:IX53_RS10355
uniprot id: A0A0G2Z9C6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1330330:IX53 RS03005
gene id: 1330330:IX53_RS03005
uniprot id: A0A0G2ZBN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1330330:IX53 RS09950
gene id: 1330330:IX53_RS09950
uniprot id: A0A0G2ZH51
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1330330:IX53 RS04040
gene id: 1330330:IX53_RS04040
uniprot id: A0A0G2ZE85
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1330330:IX53 RS02995
gene id: 1330330:IX53_RS02995
uniprot id: A0A0G2Z5Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

1330330:IX53 RS07190
gene id: 1330330:IX53_RS07190
uniprot id: A0A0G2Z7Q9
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1330330:IX53 RS02705
gene id: 1330330:IX53_RS02705
uniprot id: A0A0G2Z9Z0
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1330330:IX53 RS00250
gene id: 1330330:IX53_RS00250
uniprot id: A0A0G2ZCM6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1330330:IX53 RS08775
gene id: 1330330:IX53_RS08775
uniprot id: A0A0G2ZEB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1330330:IX53 RS01025
gene id: 1330330:IX53_RS01025
uniprot id: A0A0G2Z4U5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1330330:IX53 RS00795
gene id: 1330330:IX53_RS00795
uniprot id: A0A0G2ZAJ5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1330330:IX53 RS02835
gene id: 1330330:IX53_RS02835
uniprot id: A0A0G2Z5P0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1330330:IX53 RS01500
gene id: 1330330:IX53_RS01500
uniprot id: A0A0G2ZD23
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1330330:IX53 RS08190
gene id: 1330330:IX53_RS08190
uniprot id: A0A0G2ZG54
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1330330:IX53 RS01125
gene id: 1330330:IX53_RS01125
uniprot id: A0A0G2Z9A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1330330:IX53 RS06805
gene id: 1330330:IX53_RS06805
uniprot id: A0A0G2ZDD4
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS00510
gene id: 1330330:IX53_RS00510
uniprot id: A0A0G2Z903
names: Similarity
messages: Belongs to the ribF family.

1330330:IX53 RS08750
gene id: 1330330:IX53_RS08750
uniprot id: A0A0G2ZEA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1330330:IX53 RS00865
gene id: 1330330:IX53_RS00865
uniprot id: A0A0G2Z962
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS00015
gene id: 1330330:IX53_RS00015
uniprot id: A0A0G2ZCJ4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1330330:IX53 RS00895
gene id: 1330330:IX53_RS00895
uniprot id: A0A0G2Z4S5
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1330330:IX53 RS01300
gene id: 1330330:IX53_RS01300
uniprot id: A0A0G2ZD05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1330330:IX53 RS01555
gene id: 1330330:IX53_RS01555
uniprot id: A0A0G2ZD30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

1330330:IX53 RS02210
gene id: 1330330:IX53_RS02210
uniprot id: A0A0G2ZB82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1330330:IX53 RS07130
gene id: 1330330:IX53_RS07130
uniprot id: A0A0G2ZC19
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1330330:IX53 RS09765
gene id: 1330330:IX53_RS09765
uniprot id: A0A0G2ZDB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1330330:IX53 RS10120
gene id: 1330330:IX53_RS10120
uniprot id: A0A0G2ZH66
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1330330:IX53 RS02700
gene id: 1330330:IX53_RS02700
uniprot id: A0A0G2Z5L7
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1330330:IX53 RS01880
gene id: 1330330:IX53_RS01880
uniprot id: A0A0G2ZD83
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1330330:IX53 RS10115
gene id: 1330330:IX53_RS10115
uniprot id: A0A0G2Z985
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1330330:IX53 RS06770
gene id: 1330330:IX53_RS06770
uniprot id: A0A0G2Z7P4
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS01280
gene id: 1330330:IX53_RS01280
uniprot id: A0A0G2Z4Y5
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS01010
gene id: 1330330:IX53_RS01010
uniprot id: A0A0G2ZCY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1330330:IX53 RS10250
gene id: 1330330:IX53_RS10250
uniprot id: A0A0G2Z964
names: Similarity
messages: Belongs to the Fur family.

1330330:IX53 RS09540
gene id: 1330330:IX53_RS09540
uniprot id: A0A0G2ZGZ4
names: Subcellular Location Annotation
messages: Cytoplasm

1330330:IX53 RS00455
gene id: 1330330:IX53_RS00455
uniprot id: A0A0G2Z4K6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1330330:IX53 RS01920
gene id: 1330330:IX53_RS01920
uniprot id: A0A0G2Z9L1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1330330:IX53 RS00415
gene id: 1330330:IX53_RS00415
uniprot id: A0A0G2ZCR6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1330330:IX53 RS05005
gene id: 1330330:IX53_RS05005
uniprot id: A0A0G2Z6P4
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1330330:IX53 RS08815
gene id: 1330330:IX53_RS08815
uniprot id: A0A0G2Z8K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1330330:IX53 RS00970
gene id: 1330330:IX53_RS00970
uniprot id: A0A0G2Z977
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1330330:IX53 RS02065
gene id: 1330330:IX53_RS02065
uniprot id: A0A0G2ZB35
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS09970
gene id: 1330330:IX53_RS09970
uniprot id: A0A0G2Z965
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS05345
gene id: 1330330:IX53_RS05345
uniprot id: A0A0G2ZES6
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1330330:IX53 RS08545
gene id: 1330330:IX53_RS08545
uniprot id: A0A0G2Z8A9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1330330:IX53 RS03050
gene id: 1330330:IX53_RS03050
uniprot id: A0A0G2ZDU6
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1330330:IX53 RS01430
gene id: 1330330:IX53_RS01430
uniprot id: A0A0G2ZD16
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1330330:IX53 RS05585
gene id: 1330330:IX53_RS05585
uniprot id: A0A0G2Z738
names: Similarity
messages: Belongs to the CinA family.

1330330:IX53 RS00235
gene id: 1330330:IX53_RS00235
uniprot id: A0A0G2Z8W2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1330330:IX53 RS02635
gene id: 1330330:IX53_RS02635
uniprot id: A0A0G2Z5Q6
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS05140
gene id: 1330330:IX53_RS05140
uniprot id: A0A0G2ZB19
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1330330:IX53 RS09940
gene id: 1330330:IX53_RS09940
uniprot id: A0A0G2ZDE6
names: Similarity
messages: Belongs to the glutamine synthetase family.

1330330:IX53 RS09675
gene id: 1330330:IX53_RS09675
uniprot id: A0A0G2Z916
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1330330:IX53 RS00310
gene id: 1330330:IX53_RS00310
uniprot id: A0A0G2Z8X3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1330330:IX53 RS04585
gene id: 1330330:IX53_RS04585
uniprot id: A0A0G2ZED9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1330330:IX53 RS07530
gene id: 1330330:IX53_RS07530
uniprot id: A0A0G2ZFV1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1330330:IX53 RS02590
gene id: 1330330:IX53_RS02590
uniprot id: A0A0G2ZDJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1330330:IX53 RS06405
gene id: 1330330:IX53_RS06405
uniprot id: A0A0G2ZFG4
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1330330:IX53 RS08180
gene id: 1330330:IX53_RS08180
uniprot id: A0A0G2ZCG2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1330330:IX53 RS02105
gene id: 1330330:IX53_RS02105
uniprot id: A0A0G2Z5B0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1330330:IX53 RS09015
gene id: 1330330:IX53_RS09015
uniprot id: A0A0G2ZGS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1330330:IX53 RS05120
gene id: 1330330:IX53_RS05120
uniprot id: A0A0G2ZEN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1330330:IX53 RS06440
gene id: 1330330:IX53_RS06440
uniprot id: A0A0G2ZFH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1330330:IX53 RS06230
gene id: 1330330:IX53_RS06230
uniprot id: A0A0G2ZBN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1330330:IX53 RS02415
gene id: 1330330:IX53_RS02415
uniprot id: A0A0G2ZDG7
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS01890
gene id: 1330330:IX53_RS01890
uniprot id: A0A0G2Z583
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1330330:IX53 RS06855
gene id: 1330330:IX53_RS06855
uniprot id: A0A0G2Z7Q8
names: Similarity
messages: Belongs to the HypE family.

1330330:IX53 RS08885
gene id: 1330330:IX53_RS08885
uniprot id: A0A0G2ZEC6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1330330:IX53 RS04060
gene id: 1330330:IX53_RS04060
uniprot id: A0A0G2ZAK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1330330:IX53 RS03760
gene id: 1330330:IX53_RS03760
uniprot id: A0A0G2Z6A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

1330330:IX53 RS09830
gene id: 1330330:IX53_RS09830
uniprot id: A0A0G2ZEV4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1330330:IX53 RS08060
gene id: 1330330:IX53_RS08060
uniprot id: A0A0G2ZDY8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1330330:IX53 RS05130
gene id: 1330330:IX53_RS05130
uniprot id: A0A0G2Z6R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1330330:IX53 RS09680
gene id: 1330330:IX53_RS09680
uniprot id: A0A0G2ZH15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1330330:IX53 RS01270
gene id: 1330330:IX53_RS01270
uniprot id: A0A0G2ZAR7
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS09690
gene id: 1330330:IX53_RS09690
uniprot id: A0A0G2Z8Y1
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1330330:IX53 RS08845
gene id: 1330330:IX53_RS08845
uniprot id: A0A0G2ZCS2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

1330330:IX53 RS00985
gene id: 1330330:IX53_RS00985
uniprot id: A0A0G2ZAM3
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1330330:IX53 RS02725
gene id: 1330330:IX53_RS02725
uniprot id: A0A0G2Z5M2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1330330:IX53 RS08225
gene id: 1330330:IX53_RS08225
uniprot id: A0A0G2ZE13
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1330330:IX53 RS06935
gene id: 1330330:IX53_RS06935
uniprot id: A0A0G2ZBZ4
names: Similarity
messages: Belongs to the class-I fumarase family.

1330330:IX53 RS03840
gene id: 1330330:IX53_RS03840
uniprot id: A0A0G2Z663
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1330330:IX53 RS08780
gene id: 1330330:IX53_RS08780
uniprot id: A0A0G2Z8F7
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1330330:IX53 RS03720
gene id: 1330330:IX53_RS03720
uniprot id: A0A0G2Z6A4
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS06345
gene id: 1330330:IX53_RS06345
uniprot id: A0A0G2ZD71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1330330:IX53 RS04165
gene id: 1330330:IX53_RS04165
uniprot id: A0A0G2ZAM1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1330330:IX53 RS02020
gene id: 1330330:IX53_RS02020
uniprot id: A0A0G2Z9M6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1330330:IX53 RS01600
gene id: 1330330:IX53_RS01600
uniprot id: A0A0G2ZAX3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1330330:IX53 RS06075
gene id: 1330330:IX53_RS06075
uniprot id: A0A0G2ZBK8
names: Similarity
messages: Belongs to the UPF0145 family.

1330330:IX53 RS04460
gene id: 1330330:IX53_RS04460
uniprot id: A0A0G2Z6F9
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1330330:IX53 RS10975
gene id: 1330330:IX53_RS10975
uniprot id: A0A0G2Z5Y0
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1330330:IX53 RS02220
gene id: 1330330:IX53_RS02220
uniprot id: A0A0G2Z9H2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1330330:IX53 RS02565
gene id: 1330330:IX53_RS02565
uniprot id: A0A0G2ZBE0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1330330:IX53 RS00370
gene id: 1330330:IX53_RS00370
uniprot id: A0A0G2Z8Y3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1330330:IX53 RS00410
gene id: 1330330:IX53_RS00410
uniprot id: A0A0G2Z9D7
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1330330:IX53 RS05745
gene id: 1330330:IX53_RS05745
uniprot id: A0A0G2Z764
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

1330330:IX53 RS06660
gene id: 1330330:IX53_RS06660
uniprot id: A0A0G2ZDA9
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

1330330:IX53 RS03620
gene id: 1330330:IX53_RS03620
uniprot id: A0A0G2ZBY3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1330330:IX53 RS09040
gene id: 1330330:IX53_RS09040
uniprot id: A0A0G2ZCZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1330330:IX53 RS08580
gene id: 1330330:IX53_RS08580
uniprot id: A0A0G2ZCN1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1330330:IX53 RS02825
gene id: 1330330:IX53_RS02825
uniprot id: A0A0G2ZDN0
names: Similarity
messages: Belongs to the UPF0166 family.

1330330:IX53 RS00200
gene id: 1330330:IX53_RS00200
uniprot id: A0A0G2ZCM2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1330330:IX53 RS09790
gene id: 1330330:IX53_RS09790
uniprot id: A0A0G2ZDC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1330330:IX53 RS01435
gene id: 1330330:IX53_RS01435
uniprot id: A0A0G2ZAU9
names: Similarity
messages: Belongs to the RutC family.

1330330:IX53 RS09875
gene id: 1330330:IX53_RS09875
uniprot id: A0A0G2ZDD5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1330330:IX53 RS02550
gene id: 1330330:IX53_RS02550
uniprot id: A0A0G2Z9W7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1330330:IX53 RS01515
gene id: 1330330:IX53_RS01515
uniprot id: A0A0G2Z526
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1330330:IX53 RS02100
gene id: 1330330:IX53_RS02100
uniprot id: A0A0G2Z9C3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1330330:IX53 RS00085
gene id: 1330330:IX53_RS00085
uniprot id: A0A0G2Z4L4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1330330:IX53 RS03145
gene id: 1330330:IX53_RS03145
uniprot id: A0A0G2Z616
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1330330:IX53 RS08915
gene id: 1330330:IX53_RS08915
uniprot id: A0A0G2ZED0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1330330:IX53 RS02945
gene id: 1330330:IX53_RS02945
uniprot id: A0A0G2Z5T5
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1330330:IX53 RS07900
gene id: 1330330:IX53_RS07900
uniprot id: A0A0G2ZCC0
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1330330:IX53 RS02920
gene id: 1330330:IX53_RS02920
uniprot id: A0A0G2Z5T3
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1330330:IX53 RS06845
gene id: 1330330:IX53_RS06845
uniprot id: A0A0G2ZBX9
names: Similarity
messages: Belongs to the HupF/HypC family.

1330330:IX53 RS06000
gene id: 1330330:IX53_RS06000
uniprot id: A0A0G2ZF99
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1330330:IX53 RS02420
gene id: 1330330:IX53_RS02420
uniprot id: A0A0G2ZBB8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

1330330:IX53 RS08870
gene id: 1330330:IX53_RS08870
uniprot id: A0A0G2ZCS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1330330:IX53 RS09070
gene id: 1330330:IX53_RS09070
uniprot id: A0A0G2Z8R4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1330330:IX53 RS04940
gene id: 1330330:IX53_RS04940
uniprot id: A0A0G2Z6T0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1330330:IX53 RS04055
gene id: 1330330:IX53_RS04055
uniprot id: A0A0G2Z693
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1330330:IX53 RS01130
gene id: 1330330:IX53_RS01130
uniprot id: A0A0G2Z523
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1330330:IX53 RS05150
gene id: 1330330:IX53_RS05150
uniprot id: A0A0G2ZEN6
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1330330:IX53 RS04640
gene id: 1330330:IX53_RS04640
uniprot id: A0A0G2Z6M8
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS02535
gene id: 1330330:IX53_RS02535
uniprot id: A0A0G2ZDI2
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1330330:IX53 RS04075
gene id: 1330330:IX53_RS04075
uniprot id: A0A0G2ZE87
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1330330:IX53 RS05600
gene id: 1330330:IX53_RS05600
uniprot id: A0A0G2Z703
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1330330:IX53 RS10020
gene id: 1330330:IX53_RS10020
uniprot id: A0A0G2Z932
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1330330:IX53 RS05100
gene id: 1330330:IX53_RS05100
uniprot id: A0A0G2ZCM0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1330330:IX53 RS05230
gene id: 1330330:IX53_RS05230
uniprot id: A0A0G2ZEQ6
names: Similarity
messages: Belongs to the UPF0111 family.

1330330:IX53 RS10265
gene id: 1330330:IX53_RS10265
uniprot id: A0A0G2ZH80
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1330330:IX53 RS01765
gene id: 1330330:IX53_RS01765
uniprot id: A0A0G2Z9J2
names: Similarity
messages: Belongs to the UPF0473 family.

1330330:IX53 RS05000
gene id: 1330330:IX53_RS05000
uniprot id: A0A0G2ZCK5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1330330:IX53 RS08435
gene id: 1330330:IX53_RS08435
uniprot id: A0A0G2Z8D6
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS04145
gene id: 1330330:IX53_RS04145
uniprot id: A0A0G2Z6F8
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1330330:IX53 RS03940
gene id: 1330330:IX53_RS03940
uniprot id: A0A0G2ZE70
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1330330:IX53 RS07240
gene id: 1330330:IX53_RS07240
uniprot id: A0A0G2ZFS5
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1330330:IX53 RS02630
gene id: 1330330:IX53_RS02630
uniprot id: A0A0G2Z9X7
names: Similarity
messages: Belongs to the UPF0145 family.

1330330:IX53 RS03850
gene id: 1330330:IX53_RS03850
uniprot id: A0A0G2Z6C1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1330330:IX53 RS11010
gene id: 1330330:IX53_RS11010
uniprot id: A0A0G2Z5D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1330330:IX53 RS06475
gene id: 1330330:IX53_RS06475
uniprot id: A0A0G2Z7J4
names: Subcellular Location Annotation
messages: Membrane

1330330:IX53 RS04170
gene id: 1330330:IX53_RS04170
uniprot id: A0A0G2Z6G3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.