1318743:PU02 RS02120
gene id: 1318743:PU02_RS02120
uniprot id: A0A0M4L7M7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1318743:PU02 RS02675
gene id: 1318743:PU02_RS02675
uniprot id: A0A0M3T2V3
names: Similarity
messages: Belongs to the peptidase C40 family.

1318743:PU02 RS03845
gene id: 1318743:PU02_RS03845
uniprot id: A0A0M4LGN8
names: Similarity
messages: Belongs to the peptidase M24B family.

1318743:PU02 RS02040
gene id: 1318743:PU02_RS02040
uniprot id: A0A0M4LG03
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1318743:PU02 RS02840
gene id: 1318743:PU02_RS02840
uniprot id: A0A0M4LIA5
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1318743:PU02 RS01620
gene id: 1318743:PU02_RS01620
uniprot id: A0A0M5KSE1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1318743:PU02 RS03765
gene id: 1318743:PU02_RS03765
uniprot id: A0A0M3T300
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1318743:PU02 RS05380
gene id: 1318743:PU02_RS05380
uniprot id: A0A0M4L7K6
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1318743:PU02 RS01005
gene id: 1318743:PU02_RS01005
uniprot id: A0A0M4LFJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the virB8 family.
messages: Membrane

1318743:PU02 RS05340
gene id: 1318743:PU02_RS05340
uniprot id: A0A0M3T362
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1318743:PU02 RS03630
gene id: 1318743:PU02_RS03630
uniprot id: A0A0M5KX05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BA14k family.
messages: Cell membrane
messages: Has immunoglobulin-binding and hemagglutination properties, and can bind to mannose. Essential for virulence. May be involved in LPS biosynthesis or polysaccharide transport.
messages: Membrane

1318743:PU02 RS03790
gene id: 1318743:PU02_RS03790
uniprot id: A0A0M4L727
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1318743:PU02 RS02405
gene id: 1318743:PU02_RS02405
uniprot id: A0A0M4L7R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1318743:PU02 RS03585
gene id: 1318743:PU02_RS03585
uniprot id: A0A0M4L846
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1318743:PU02 RS00665
gene id: 1318743:PU02_RS00665
uniprot id: A0A0M3T2L5
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1318743:PU02 RS05505
gene id: 1318743:PU02_RS05505
uniprot id: A0A0M4LTK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1318743:PU02 RS05640
gene id: 1318743:PU02_RS05640
uniprot id: A0A0M5KZI1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1318743:PU02 RS00590
gene id: 1318743:PU02_RS00590
uniprot id: A0A0M4LHE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1318743:PU02 RS01820
gene id: 1318743:PU02_RS01820
uniprot id: A0A0M4L6D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1318743:PU02 RS02990
gene id: 1318743:PU02_RS02990
uniprot id: A0A0M4M384
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1318743:PU02 RS01700
gene id: 1318743:PU02_RS01700
uniprot id: A0A0M4L6C4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1318743:PU02 RS06020
gene id: 1318743:PU02_RS06020
uniprot id: A0A0M4LJM5
names: Similarity
messages: Belongs to the GARS family.

1318743:PU02 RS01770
gene id: 1318743:PU02_RS01770
uniprot id: A0A0M5L0W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1318743:PU02 RS00120
gene id: 1318743:PU02_RS00120
uniprot id: A0A0M4L711
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1318743:PU02 RS03050
gene id: 1318743:PU02_RS03050
uniprot id: A0A0M4M393
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1318743:PU02 RS03780
gene id: 1318743:PU02_RS03780
uniprot id: A0A0M4LIR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1318743:PU02 RS04125
gene id: 1318743:PU02_RS04125
uniprot id: A0A0M4M3Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1318743:PU02 RS00815
gene id: 1318743:PU02_RS00815
uniprot id: A0A0M3T2M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1318743:PU02 RS05645
gene id: 1318743:PU02_RS05645
uniprot id: A0A0M3T351
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

1318743:PU02 RS03680
gene id: 1318743:PU02_RS03680
uniprot id: A0A0M4M3J4
names: Subcellular Location Annotation
messages: Membrane

1318743:PU02 RS04015
gene id: 1318743:PU02_RS04015
uniprot id: A0A0M3T310
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1318743:PU02 RS04155
gene id: 1318743:PU02_RS04155
uniprot id: A0A0M4LIW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1318743:PU02 RS01755
gene id: 1318743:PU02_RS01755
uniprot id: A0A0M4LFX0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

1318743:PU02 RS02630
gene id: 1318743:PU02_RS02630
uniprot id: A0A0M4L7T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Membrane

1318743:PU02 RS05095
gene id: 1318743:PU02_RS05095
uniprot id: A0A0M4LKA7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1318743:PU02 RS05060
gene id: 1318743:PU02_RS05060
uniprot id: A0A0M3T327
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1318743:PU02 RS06000
gene id: 1318743:PU02_RS06000
uniprot id: A0A0M4LKM5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1318743:PU02 RS04135
gene id: 1318743:PU02_RS04135
uniprot id: A0A0M4LJX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1318743:PU02 RS06380
gene id: 1318743:PU02_RS06380
uniprot id: A0A0M4M4M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1318743:PU02 RS01645
gene id: 1318743:PU02_RS01645
uniprot id: A0A0M4L6B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1318743:PU02 RS00800
gene id: 1318743:PU02_RS00800
uniprot id: A0A0M4LRR9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1318743:PU02 RS01280
gene id: 1318743:PU02_RS01280
uniprot id: A0A0M4L7D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

1318743:PU02 RS01495
gene id: 1318743:PU02_RS01495
uniprot id: A0A0M4M2K8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1318743:PU02 RS00055
gene id: 1318743:PU02_RS00055
uniprot id: A0A0M4M207
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1318743:PU02 RS05675
gene id: 1318743:PU02_RS05675
uniprot id: A0A0M4LTM3
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1318743:PU02 RS01750
gene id: 1318743:PU02_RS01750
uniprot id: A0A0M3T2P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1318743:PU02 RS04085
gene id: 1318743:PU02_RS04085
uniprot id: A0A0M4M679
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1318743:PU02 RS04760
gene id: 1318743:PU02_RS04760
uniprot id: A0A0M3T340
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1318743:PU02 RS02235
gene id: 1318743:PU02_RS02235
uniprot id: A0A0M5KTL7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1318743:PU02 RS05280
gene id: 1318743:PU02_RS05280
uniprot id: A0A0M4M6R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1318743:PU02 RS02830
gene id: 1318743:PU02_RS02830
uniprot id: A0A0M4M5P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

1318743:PU02 RS04985
gene id: 1318743:PU02_RS04985
uniprot id: A0A0M3T348
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1318743:PU02 RS03640
gene id: 1318743:PU02_RS03640
uniprot id: A0A0M4LJQ0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1318743:PU02 RS03850
gene id: 1318743:PU02_RS03850
uniprot id: A0A0M4L734
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1318743:PU02 RS04240
gene id: 1318743:PU02_RS04240
uniprot id: A0A0M5KX19
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1318743:PU02 RS03065
gene id: 1318743:PU02_RS03065
uniprot id: A0A0M3T2W9
names: Similarity
messages: Belongs to the peptidase U62 family.

1318743:PU02 RS03820
gene id: 1318743:PU02_RS03820
uniprot id: U3NGQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1318743:PU02 RS00895
gene id: 1318743:PU02_RS00895
uniprot id: A0A0M3T2K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1318743:PU02 RS03090
gene id: 1318743:PU02_RS03090
uniprot id: A0A0M4L6U0
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1318743:PU02 RS02345
gene id: 1318743:PU02_RS02345
uniprot id: A0A0M4LJ81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1318743:PU02 RS01415
gene id: 1318743:PU02_RS01415
uniprot id: A0A0M4M540
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

1318743:PU02 RS01520
gene id: 1318743:PU02_RS01520
uniprot id: A0A0M4LHS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1318743:PU02 RS05730
gene id: 1318743:PU02_RS05730
uniprot id: A0A0M4L7Q5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1318743:PU02 RS02690
gene id: 1318743:PU02_RS02690
uniprot id: A0A0M4L7U1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1318743:PU02 RS02225
gene id: 1318743:PU02_RS02225
uniprot id: A0A0M4M2X2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1318743:PU02 RS03570
gene id: 1318743:PU02_RS03570
uniprot id: A0A0M5L142
names: Similarity
messages: Belongs to the YkuD family.

1318743:PU02 RS00785
gene id: 1318743:PU02_RS00785
uniprot id: A0A0M4LFG8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1318743:PU02 RS04260
gene id: 1318743:PU02_RS04260
uniprot id: A0A0M4LJZ1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1318743:PU02 RS04265
gene id: 1318743:PU02_RS04265
uniprot id: A0A0M5KSN7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1318743:PU02 RS04770
gene id: 1318743:PU02_RS04770
uniprot id: A0A0M4M6I3
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1318743:PU02 RS00570
gene id: 1318743:PU02_RS00570
uniprot id: A0A0M4L749
names: Similarity
messages: Belongs to the UPF0434 family.

1318743:PU02 RS06235
gene id: 1318743:PU02_RS06235
uniprot id: A0A0M3T399
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1318743:PU02 RS02065
gene id: 1318743:PU02_RS02065
uniprot id: A0A0M4M2U4
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1318743:PU02 RS04415
gene id: 1318743:PU02_RS04415
uniprot id: A0A0M3T326
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1318743:PU02 RS02045
gene id: 1318743:PU02_RS02045
uniprot id: A0A0M3T2S5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1318743:PU02 RS04190
gene id: 1318743:PU02_RS04190
uniprot id: A0A0M4L8C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1318743:PU02 RS04140
gene id: 1318743:PU02_RS04140
uniprot id: A0A0M5KSN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1318743:PU02 RS04105
gene id: 1318743:PU02_RS04105
uniprot id: A0A0M4L759
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1318743:PU02 RS01695
gene id: 1318743:PU02_RS01695
uniprot id: A0A0M4LFW2
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1318743:PU02 RS00520
gene id: 1318743:PU02_RS00520
uniprot id: A0A0M3T2K9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1318743:PU02 RS02650
gene id: 1318743:PU02_RS02650
uniprot id: A0A0M4LI81
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1318743:PU02 RS00515
gene id: 1318743:PU02_RS00515
uniprot id: A0A0M4LIK6
names: Function
names: Similarity
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.

1318743:PU02 RS04220
gene id: 1318743:PU02_RS04220
uniprot id: A0A0M4LIX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

1318743:PU02 RS01535
gene id: 1318743:PU02_RS01535
uniprot id: A0A0M3T2Q3
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

1318743:PU02 RS05545
gene id: 1318743:PU02_RS05545
uniprot id: A0A0M4LH87
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1318743:PU02 RS04080
gene id: 1318743:PU02_RS04080
uniprot id: A0A0M5KZC3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1318743:PU02 RS06335
gene id: 1318743:PU02_RS06335
uniprot id: A0A0M5KSV0
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1318743:PU02 RS00995
gene id: 1318743:PU02_RS00995
uniprot id: A0A0M3T2M7
names: Similarity
messages: Belongs to the TrbL/VirB6 family.

1318743:PU02 RS02920
gene id: 1318743:PU02_RS02920
uniprot id: A0A0M4LGF1
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1318743:PU02 RS02095
gene id: 1318743:PU02_RS02095
uniprot id: A0A0M4LI10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1318743:PU02 RS04630
gene id: 1318743:PU02_RS04630
uniprot id: A0A0M4LK49
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1318743:PU02 RS01515
gene id: 1318743:PU02_RS01515
uniprot id: A0A0M4M553
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1318743:PU02 RS05685
gene id: 1318743:PU02_RS05685
uniprot id: A0A0M4M4C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1318743:PU02 RS03475
gene id: 1318743:PU02_RS03475
uniprot id: A0A0M4M5Y8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1318743:PU02 RS05135
gene id: 1318743:PU02_RS05135
uniprot id: A0A0M3T354
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1318743:PU02 RS06285
gene id: 1318743:PU02_RS06285
uniprot id: A0A0M5KSV6
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1318743:PU02 RS04175
gene id: 1318743:PU02_RS04175
uniprot id: A0A0M4LT27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1318743:PU02 RS05800
gene id: 1318743:PU02_RS05800
uniprot id: A0A0M5KX75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1318743:PU02 RS05255
gene id: 1318743:PU02_RS05255
uniprot id: A0A0M4M470
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1318743:PU02 RS05465
gene id: 1318743:PU02_RS05465
uniprot id: A0A0M3T343
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1318743:PU02 RS04945
gene id: 1318743:PU02_RS04945
uniprot id: A0A0M4LTD6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1318743:PU02 RS01335
gene id: 1318743:PU02_RS01335
uniprot id: A0A0M4M2I0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1318743:PU02 RS02455
gene id: 1318743:PU02_RS02455
uniprot id: A0A0M5KWW5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1318743:PU02 RS02130
gene id: 1318743:PU02_RS02130
uniprot id: A0A0M3T2S9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1318743:PU02 RS02735
gene id: 1318743:PU02_RS02735
uniprot id: A0A0M4LSI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1318743:PU02 RS05185
gene id: 1318743:PU02_RS05185
uniprot id: A0A0M3T356
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1318743:PU02 RS06180
gene id: 1318743:PU02_RS06180
uniprot id: A0A0M4M733
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1318743:PU02 RS04250
gene id: 1318743:PU02_RS04250
uniprot id: A0A0M4M3R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1318743:PU02 RS04805
gene id: 1318743:PU02_RS04805
uniprot id: A0A0M5L181
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1318743:PU02 RS03370
gene id: 1318743:PU02_RS03370
uniprot id: A0A0M4L6X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1318743:PU02 RS01555
gene id: 1318743:PU02_RS01555
uniprot id: A0A0M4L7G5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1318743:PU02 RS02575
gene id: 1318743:PU02_RS02575
uniprot id: A0A0M4M326
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1318743:PU02 RS02125
gene id: 1318743:PU02_RS02125
uniprot id: A0A0M4LJ55
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1318743:PU02 RS05680
gene id: 1318743:PU02_RS05680
uniprot id: A0A0M5L190
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1318743:PU02 RS03095
gene id: 1318743:PU02_RS03095
uniprot id: A0A0M4LSN2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1318743:PU02 RS02510
gene id: 1318743:PU02_RS02510
uniprot id: A0A0M5KSH0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1318743:PU02 RS03710
gene id: 1318743:PU02_RS03710
uniprot id: A0A0M4LIR0
names: Similarity
messages: Belongs to the UPF0260 family.

1318743:PU02 RS06070
gene id: 1318743:PU02_RS06070
uniprot id: A0A0M4LJN4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1318743:PU02 RS06210
gene id: 1318743:PU02_RS06210
uniprot id: A0A0M5KUT2
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

1318743:PU02 RS01470
gene id: 1318743:PU02_RS01470
uniprot id: A0A0M4LFR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1318743:PU02 RS03390
gene id: 1318743:PU02_RS03390
uniprot id: A0A0M4M3E9
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

1318743:PU02 RS05140
gene id: 1318743:PU02_RS05140
uniprot id: A0A0M5L191
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1318743:PU02 RS01580
gene id: 1318743:PU02_RS01580
uniprot id: A0A0M4LHT4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1318743:PU02 RS05400
gene id: 1318743:PU02_RS05400
uniprot id: A0A0M4M487
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

1318743:PU02 RS03085
gene id: 1318743:PU02_RS03085
uniprot id: A0A0M4LGC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1318743:PU02 RS05020
gene id: 1318743:PU02_RS05020
uniprot id: A0A0M4LKA0
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1318743:PU02 RS02680
gene id: 1318743:PU02_RS02680
uniprot id: A0A0M5L112
names: Similarity
messages: Belongs to the peptidase M17 family.

1318743:PU02 RS05245
gene id: 1318743:PU02_RS05245
uniprot id: A0A0M5KSR8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1318743:PU02 RS03020
gene id: 1318743:PU02_RS03020
uniprot id: A0A0M4M5S1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1318743:PU02 RS05230
gene id: 1318743:PU02_RS05230
uniprot id: A0A0M3T358
names: Similarity
messages: Belongs to the peptidase S11 family.

1318743:PU02 RS04040
gene id: 1318743:PU02_RS04040
uniprot id: A0A0M4L754
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1318743:PU02 RS02240
gene id: 1318743:PU02_RS02240
uniprot id: A0A0M3T2R2
names: Similarity
messages: Belongs to the thioredoxin family.

1318743:PU02 RS00695
gene id: 1318743:PU02_RS00695
uniprot id: A0A0M3T2J4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1318743:PU02 RS00745
gene id: 1318743:PU02_RS00745
uniprot id: A0A0M3T2J6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1318743:PU02 RS00540
gene id: 1318743:PU02_RS00540
uniprot id: A0A0M4LHD9
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1318743:PU02 RS01765
gene id: 1318743:PU02_RS01765
uniprot id: A0A0M3T2R3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1318743:PU02 RS03815
gene id: 1318743:PU02_RS03815
uniprot id: A0A0M4L878
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1318743:PU02 RS06305
gene id: 1318743:PU02_RS06305
uniprot id: A0A0M4LTV6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1318743:PU02 RS04150
gene id: 1318743:PU02_RS04150
uniprot id: A0A0M4M687
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1318743:PU02 RS02640
gene id: 1318743:PU02_RS02640
uniprot id: A0A0M5KSI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1318743:PU02 RS05655
gene id: 1318743:PU02_RS05655
uniprot id: A0A0M4LJH8
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1318743:PU02 RS05325
gene id: 1318743:PU02_RS05325
uniprot id: A0A0M5KUQ1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1318743:PU02 RS03460
gene id: 1318743:PU02_RS03460
uniprot id: A0A0M4LJM8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1318743:PU02 RS05650
gene id: 1318743:PU02_RS05650
uniprot id: A0A0M4M6W4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1318743:PU02 RS04610
gene id: 1318743:PU02_RS04610
uniprot id: A0A0M3T334
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1318743:PU02 RS05220
gene id: 1318743:PU02_RS05220
uniprot id: A0A0M5KSR9
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1318743:PU02 RS02610
gene id: 1318743:PU02_RS02610
uniprot id: A0A0M3T2S8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1318743:PU02 RS05415
gene id: 1318743:PU02_RS05415
uniprot id: A0A0M3T341
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1318743:PU02 RS06010
gene id: 1318743:PU02_RS06010
uniprot id: A0A0M5KSU6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1318743:PU02 RS05320
gene id: 1318743:PU02_RS05320
uniprot id: A0A0M4LTI2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1318743:PU02 RS01775
gene id: 1318743:PU02_RS01775
uniprot id: A0A0M4M2Q2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1318743:PU02 RS04835
gene id: 1318743:PU02_RS04835
uniprot id: A0A0M4M6J3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1318743:PU02 RS04965
gene id: 1318743:PU02_RS04965
uniprot id: A0A0M3T323
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1318743:PU02 RS00680
gene id: 1318743:PU02_RS00680
uniprot id: A0A0M5L0U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1318743:PU02 RS05955
gene id: 1318743:PU02_RS05955
uniprot id: A0A0M4M6Z9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1318743:PU02 RS04780
gene id: 1318743:PU02_RS04780
uniprot id: A0A0M4L7D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1318743:PU02 RS05970
gene id: 1318743:PU02_RS05970
uniprot id: A0A0M4L7T2
names: Similarity
messages: Belongs to the peptidase U62 family.

1318743:PU02 RS04410
gene id: 1318743:PU02_RS04410
uniprot id: A0A0M4LGW3
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1318743:PU02 RS06250
gene id: 1318743:PU02_RS06250
uniprot id: A0A0M4LJQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1318743:PU02 RS01740
gene id: 1318743:PU02_RS01740
uniprot id: A0A0M4M583
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1318743:PU02 RS05845
gene id: 1318743:PU02_RS05845
uniprot id: A0A0M4LHC6
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1318743:PU02 RS02805
gene id: 1318743:PU02_RS02805
uniprot id: A0A0M4M362
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1318743:PU02 RS00925
gene id: 1318743:PU02_RS00925
uniprot id: A0A0M4LRT6
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1318743:PU02 RS04145
gene id: 1318743:PU02_RS04145
uniprot id: A0A0M3T2Z2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1318743:PU02 RS02315
gene id: 1318743:PU02_RS02315
uniprot id: A0A0M4LG40
names: Subcellular Location Annotation
messages: Membrane

1318743:PU02 RS06170
gene id: 1318743:PU02_RS06170
uniprot id: A0A0M5KTZ8
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family.

1318743:PU02 RS05010
gene id: 1318743:PU02_RS05010
uniprot id: A0A0M5KUP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1318743:PU02 RS04335
gene id: 1318743:PU02_RS04335
uniprot id: A0A0M4M6B8
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1318743:PU02 RS04310
gene id: 1318743:PU02_RS04310
uniprot id: A0A0M4M3T1
names: Similarity
messages: Belongs to the HesB/IscA family.

1318743:PU02 RS04550
gene id: 1318743:PU02_RS04550
uniprot id: A0A0M4M3W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1318743:PU02 RS03575
gene id: 1318743:PU02_RS03575
uniprot id: A0A0M4M3H8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1318743:PU02 RS03400
gene id: 1318743:PU02_RS03400
uniprot id: A0A0M4LJL8
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1318743:PU02 RS02420
gene id: 1318743:PU02_RS02420
uniprot id: A0A0M4M5I6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1318743:PU02 RS03130
gene id: 1318743:PU02_RS03130
uniprot id: A0A0M4M5T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1318743:PU02 RS04095
gene id: 1318743:PU02_RS04095
uniprot id: A0A0M3T2Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1318743:PU02 RS01720
gene id: 1318743:PU02_RS01720
uniprot id: A0A0M3T2R1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1318743:PU02 RS04765
gene id: 1318743:PU02_RS04765
uniprot id: A0A0M5KSQ4
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1318743:PU02 RS02570
gene id: 1318743:PU02_RS02570
uniprot id: A0A0M3T2S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1318743:PU02 RS03115
gene id: 1318743:PU02_RS03115
uniprot id: A0A0M4L7Y9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1318743:PU02 RS04505
gene id: 1318743:PU02_RS04505
uniprot id: A0A0M4LK28
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.
messages: Hydrolyzes indole-3-acetamide (IAM) into indole-3-acetic acid (IAA).

1318743:PU02 RS05080
gene id: 1318743:PU02_RS05080
uniprot id: A0A0M4M444
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1318743:PU02 RS04930
gene id: 1318743:PU02_RS04930
uniprot id: A0A0M4LH27
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1318743:PU02 RS02160
gene id: 1318743:PU02_RS02160
uniprot id: A0A0M3T2Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1318743:PU02 RS05605
gene id: 1318743:PU02_RS05605
uniprot id: A0A0M4LH96
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1318743:PU02 RS02230
gene id: 1318743:PU02_RS02230
uniprot id: A0A0M4LJ68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1318743:PU02 RS00690
gene id: 1318743:PU02_RS00690
uniprot id: A0A0M4L763
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1318743:PU02 RS02745
gene id: 1318743:PU02_RS02745
uniprot id: A0A0M4M352
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1318743:PU02 RS02795
gene id: 1318743:PU02_RS02795
uniprot id: A0A0M5KSI1
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1318743:PU02 RS05785
gene id: 1318743:PU02_RS05785
uniprot id: A0A0M4L7R3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1318743:PU02 RS04030
gene id: 1318743:PU02_RS04030
uniprot id: A0A0M4LIU6
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1318743:PU02 RS06360
gene id: 1318743:PU02_RS06360
uniprot id: A0A0M3T3A4
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1318743:PU02 RS05930
gene id: 1318743:PU02_RS05930
uniprot id: A0A0M4M4F7
names: Similarity
messages: Belongs to the peptidase M16 family.

1318743:PU02 RS00545
gene id: 1318743:PU02_RS00545
uniprot id: A0A0M4LFD7
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1318743:PU02 RS01510
gene id: 1318743:PU02_RS01510
uniprot id: A0A0M5KSE4
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1318743:PU02 RS03740
gene id: 1318743:PU02_RS03740
uniprot id: A0A0M3T2X7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1318743:PU02 RS01310
gene id: 1318743:PU02_RS01310
uniprot id: A0A0M4L674
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1318743:PU02 RS04890
gene id: 1318743:PU02_RS04890
uniprot id: A0A0M4L8M6
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1318743:PU02 RS03000
gene id: 1318743:PU02_RS03000
uniprot id: A0A0M3T2U4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1318743:PU02 RS05270
gene id: 1318743:PU02_RS05270
uniprot id: A0A0M3T360
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1318743:PU02 RS02255
gene id: 1318743:PU02_RS02255
uniprot id: A0A0M4LG30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1318743:PU02 RS06200
gene id: 1318743:PU02_RS06200
uniprot id: A0A0M4L7W3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

1318743:PU02 RS02760
gene id: 1318743:PU02_RS02760
uniprot id: A0A0M4LJD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1318743:PU02 RS04055
gene id: 1318743:PU02_RS04055
uniprot id: A0A0M5KUL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1318743:PU02 RS00790
gene id: 1318743:PU02_RS00790
uniprot id: A0A0M4L612
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1318743:PU02 RS00075
gene id: 1318743:PU02_RS00075
uniprot id: A0A0M4M4L4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1318743:PU02 RS03905
gene id: 1318743:PU02_RS03905
uniprot id: A0A0M4LGP7
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1318743:PU02 RS03705
gene id: 1318743:PU02_RS03705
uniprot id: A0A0M4M628
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1318743:PU02 RS01890
gene id: 1318743:PU02_RS01890
uniprot id: A0A0M4M2R9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1318743:PU02 RS04470
gene id: 1318743:PU02_RS04470
uniprot id: A0A0M4LGX0
names: Similarity
messages: Belongs to the DprA/Smf family.

1318743:PU02 RS05155
gene id: 1318743:PU02_RS05155
uniprot id: A0A0M4LKB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1318743:PU02 RS05570
gene id: 1318743:PU02_RS05570
uniprot id: A0A0M4M4B1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1318743:PU02 RS04235
gene id: 1318743:PU02_RS04235
uniprot id: A0A0M4LT32
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1318743:PU02 RS06225
gene id: 1318743:PU02_RS06225
uniprot id: A0A0M4L943
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1318743:PU02 RS06140
gene id: 1318743:PU02_RS06140
uniprot id: A0A0M4LTT3
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1318743:PU02 RS00025
gene id: 1318743:PU02_RS00025
uniprot id: A0A0M4L5T1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1318743:PU02 RS05550
gene id: 1318743:PU02_RS05550
uniprot id: A0A0M4L7N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1318743:PU02 RS05510
gene id: 1318743:PU02_RS05510
uniprot id: A0A0M5KX64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1318743:PU02 RS05975
gene id: 1318743:PU02_RS05975
uniprot id: A0A0M4LTR1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1318743:PU02 RS04755
gene id: 1318743:PU02_RS04755
uniprot id: A0A0M4LK66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1318743:PU02 RS04695
gene id: 1318743:PU02_RS04695
uniprot id: A0A0M4LK58
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1318743:PU02 RS01660
gene id: 1318743:PU02_RS01660
uniprot id: A0A0M3T2N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1318743:PU02 RS01985
gene id: 1318743:PU02_RS01985
uniprot id: A0A0M4L6G1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1318743:PU02 RS02490
gene id: 1318743:PU02_RS02490
uniprot id: A0A0M4LI60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1318743:PU02 RS01465
gene id: 1318743:PU02_RS01465
uniprot id: A0A0M4LHR6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1318743:PU02 RS03450
gene id: 1318743:PU02_RS03450
uniprot id: A0A0M4L831
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1318743:PU02 RS01675
gene id: 1318743:PU02_RS01675
uniprot id: A0A0M4LJ03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1318743:PU02 RS02775
gene id: 1318743:PU02_RS02775
uniprot id: A0A0M3T2V7
names: Similarity
messages: Belongs to the PhoH family.

1318743:PU02 RS01440
gene id: 1318743:PU02_RS01440
uniprot id: A0A0M4M2J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1318743:PU02 RS05615
gene id: 1318743:PU02_RS05615
uniprot id: A0A0M4LTL7
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1318743:PU02 RS02355
gene id: 1318743:PU02_RS02355
uniprot id: A0A0M5KSH8
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1318743:PU02 RS05815
gene id: 1318743:PU02_RS05815
uniprot id: A0A0M4L8Z0
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1318743:PU02 RS00870
gene id: 1318743:PU02_RS00870
uniprot id: A0A0M5KUA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1318743:PU02 RS03670
gene id: 1318743:PU02_RS03670
uniprot id: A0A0M4L713
names: Subcellular Location Annotation
messages: Cytoplasm

1318743:PU02 RS04100
gene id: 1318743:PU02_RS04100
uniprot id: A0A0M4LGS1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1318743:PU02 RS00920
gene id: 1318743:PU02_RS00920
uniprot id: A0A0M4L626
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1318743:PU02 RS02695
gene id: 1318743:PU02_RS02695
uniprot id: A0A0M4LJC4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1318743:PU02 RS01685
gene id: 1318743:PU02_RS01685
uniprot id: A0A0M5KTJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1318743:PU02 RS03750
gene id: 1318743:PU02_RS03750
uniprot id: A0A0M4M3K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1318743:PU02 RS03560
gene id: 1318743:PU02_RS03560
uniprot id: A0A0M3T2W8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1318743:PU02 RS00880
gene id: 1318743:PU02_RS00880
uniprot id: A0A0M4L781
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1318743:PU02 RS03900
gene id: 1318743:PU02_RS03900
uniprot id: A0A0M4LIT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1318743:PU02 RS04885
gene id: 1318743:PU02_RS04885
uniprot id: A0A0M5KX44
names: Function
names: Similarity
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: May be required for disulfide bond formation in some proteins.

1318743:PU02 RS01410
gene id: 1318743:PU02_RS01410
uniprot id: A0A0M5KTJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1318743:PU02 RS04075
gene id: 1318743:PU02_RS04075
uniprot id: A0A0M4LJW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1318743:PU02 RS03375
gene id: 1318743:PU02_RS03375
uniprot id: A0A0M4LSS1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1318743:PU02 RS05920
gene id: 1318743:PU02_RS05920
uniprot id: A0A0M4LTQ3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1318743:PU02 RS05820
gene id: 1318743:PU02_RS05820
uniprot id: A0A0M4LKK3
names: Similarity
messages: Belongs to the peptidase M1 family.

1318743:PU02 RS03045
gene id: 1318743:PU02_RS03045
uniprot id: A0A0M3T2U6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1318743:PU02 RS02820
gene id: 1318743:PU02_RS02820
uniprot id: A0A0M3T2V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1318743:PU02 RS00105
gene id: 1318743:PU02_RS00105
uniprot id: A0A0M4LRJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.

1318743:PU02 RS04870
gene id: 1318743:PU02_RS04870
uniprot id: A0A0M4L7E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1318743:PU02 RS02725
gene id: 1318743:PU02_RS02725
uniprot id: A0A0M3T2V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1318743:PU02 RS03600
gene id: 1318743:PU02_RS03600
uniprot id: A0A0M4M605
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1318743:PU02 RS01930
gene id: 1318743:PU02_RS01930
uniprot id: A0A0M4L6F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1318743:PU02 RS05590
gene id: 1318743:PU02_RS05590
uniprot id: A0A0M4M6V7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1318743:PU02 RS04640
gene id: 1318743:PU02_RS04640
uniprot id: A0A0M3T311
names: Function
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

1318743:PU02 RS02655
gene id: 1318743:PU02_RS02655
uniprot id: A0A0M3T2T0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1318743:PU02 RS04735
gene id: 1318743:PU02_RS04735
uniprot id: A0A0M5L161
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

1318743:PU02 RS00725
gene id: 1318743:PU02_RS00725
uniprot id: A0A0M4LFG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1318743:PU02 RS02390
gene id: 1318743:PU02_RS02390
uniprot id: A0A0M4LSD3
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1318743:PU02 RS03380
gene id: 1318743:PU02_RS03380
uniprot id: A0A0M3T2Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1318743:PU02 RS03260
gene id: 1318743:PU02_RS03260
uniprot id: A0A0M4LGF1
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1318743:PU02 RS04580
gene id: 1318743:PU02_RS04580
uniprot id: A0A0M4LJ30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1318743:PU02 RS01950
gene id: 1318743:PU02_RS01950
uniprot id: A0A0M3T2S1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1318743:PU02 RS03315
gene id: 1318743:PU02_RS03315
uniprot id: A0A0M3T2V8
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1318743:PU02 RS05530
gene id: 1318743:PU02_RS05530
uniprot id: A0A0M5KSS9
names: Subcellular Location Annotation
messages: Membrane

1318743:PU02 RS03590
gene id: 1318743:PU02_RS03590
uniprot id: A0A0M4LJP1
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1318743:PU02 RS02340
gene id: 1318743:PU02_RS02340
uniprot id: A0A0M4L7Q3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1318743:PU02 RS04330
gene id: 1318743:PU02_RS04330
uniprot id: A0A0M5KTT3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1318743:PU02 RS01825
gene id: 1318743:PU02_RS01825
uniprot id: A0A0M5L0Y2
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1318743:PU02 RS05200
gene id: 1318743:PU02_RS05200
uniprot id: A0A0M4M461
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1318743:PU02 RS02150
gene id: 1318743:PU02_RS02150
uniprot id: A0A0M4LG15
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1318743:PU02 RS05635
gene id: 1318743:PU02_RS05635
uniprot id: A0A0M4LKI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1318743:PU02 RS04390
gene id: 1318743:PU02_RS04390
uniprot id: A0A0M5KZD3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1318743:PU02 RS05265
gene id: 1318743:PU02_RS05265
uniprot id: A0A0M4LKD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1318743:PU02 RS01500
gene id: 1318743:PU02_RS01500
uniprot id: A0A0M3T2Q1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1318743:PU02 RS01010
gene id: 1318743:PU02_RS01010
uniprot id: A0A0M4L633
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

1318743:PU02 RS02020
gene id: 1318743:PU02_RS02020
uniprot id: A0A0M5KZ52
names: Subcellular Location Annotation
messages: Membrane

1318743:PU02 RS02605
gene id: 1318743:PU02_RS02605
uniprot id: A0A0M4L6N6
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1318743:PU02 RS01295
gene id: 1318743:PU02_RS01295
uniprot id: A0A0M4LHP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1318743:PU02 RS02015
gene id: 1318743:PU02_RS02015
uniprot id: A0A0M4LJ45
names: Subcellular Location Annotation
messages: Membrane

1318743:PU02 RS06120
gene id: 1318743:PU02_RS06120
uniprot id: A0A0M4M725
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1318743:PU02 RS05610
gene id: 1318743:PU02_RS05610
uniprot id: A0A0M4L7P5
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1318743:PU02 RS06035
gene id: 1318743:PU02_RS06035
uniprot id: A0A0M3T367
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1318743:PU02 RS03405
gene id: 1318743:PU02_RS03405
uniprot id: A0A0M5KTQ5
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1318743:PU02 RS06080
gene id: 1318743:PU02_RS06080
uniprot id: A0A0M4LHF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1318743:PU02 RS05765
gene id: 1318743:PU02_RS05765
uniprot id: A0A0M5KST0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1318743:PU02 RS04010
gene id: 1318743:PU02_RS04010
uniprot id: A0A0M4LJV1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1318743:PU02 RS05260
gene id: 1318743:PU02_RS05260
uniprot id: A0A0M4L8S3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1318743:PU02 RS01715
gene id: 1318743:PU02_RS01715
uniprot id: A0A0M4M2P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1318743:PU02 RS03635
gene id: 1318743:PU02_RS03635
uniprot id: A0A0M4L855
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1318743:PU02 RS01435
gene id: 1318743:PU02_RS01435
uniprot id: A0A0M3T2M6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1318743:PU02 RS03785
gene id: 1318743:PU02_RS03785
uniprot id: A0A0M4LGN0
names: Subcellular Location Annotation
messages: Membrane

1318743:PU02 RS01735
gene id: 1318743:PU02_RS01735
uniprot id: A0A0M5KZ44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1318743:PU02 RS05170
gene id: 1318743:PU02_RS05170
uniprot id: A0A0M4M6P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1318743:PU02 RS05475
gene id: 1318743:PU02_RS05475
uniprot id: A0A0M5KSS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1318743:PU02 RS01955
gene id: 1318743:PU02_RS01955
uniprot id: A0A0M4L7K8
names: Subcellular Location Annotation
messages: Membrane

1318743:PU02 RS02295
gene id: 1318743:PU02_RS02295
uniprot id: A0A0M5KZ62
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1318743:PU02 RS01450
gene id: 1318743:PU02_RS01450
uniprot id: A0A0M4LIX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1318743:PU02 RS04570
gene id: 1318743:PU02_RS04570
uniprot id: A0A0M5KSP8
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1318743:PU02 RS04115
gene id: 1318743:PU02_RS04115
uniprot id: A0A0M3T314
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1318743:PU02 RS01975
gene id: 1318743:PU02_RS01975
uniprot id: A0A0M4LHZ3
names: Similarity
messages: Belongs to the peptidase S11 family.

1318743:PU02 RS01790
gene id: 1318743:PU02_RS01790
uniprot id: A0A0M5KSF7
names: Similarity
messages: Belongs to the BolA/IbaG family.

1318743:PU02 RS03685
gene id: 1318743:PU02_RS03685
uniprot id: A0A0M4L864
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1318743:PU02 RS02055
gene id: 1318743:PU02_RS02055
uniprot id: A0A0M4LS80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1318743:PU02 RS03855
gene id: 1318743:PU02_RS03855
uniprot id: A0A0M4LSY5
names: Similarity
messages: Belongs to the SCO1/2 family.

1318743:PU02 RS03665
gene id: 1318743:PU02_RS03665
uniprot id: A0A0M4LGK9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1318743:PU02 RS03355
gene id: 1318743:PU02_RS03355
uniprot id: A0A0M4M5X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1318743:PU02 RS03395
gene id: 1318743:PU02_RS03395
uniprot id: A0A0M4L825
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1318743:PU02 RS05695
gene id: 1318743:PU02_RS05695
uniprot id: A0A0M3T353
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1318743:PU02 RS01015
gene id: 1318743:PU02_RS01015
uniprot id: A0A0M4LRU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

1318743:PU02 RS01640
gene id: 1318743:PU02_RS01640
uniprot id: A0A0M4LFV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1318743:PU02 RS06135
gene id: 1318743:PU02_RS06135
uniprot id: A0A0M4L7V5
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1318743:PU02 RS05175
gene id: 1318743:PU02_RS05175
uniprot id: A0A0M4LJB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell inner membrane
messages: Membrane

1318743:PU02 RS00095
gene id: 1318743:PU02_RS00095
uniprot id: A0A0M4LF84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane

1318743:PU02 RS01630
gene id: 1318743:PU02_RS01630
uniprot id: A0A0M3T2Q7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1318743:PU02 RS05790
gene id: 1318743:PU02_RS05790
uniprot id: A0A0M3T357
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

1318743:PU02 RS04825
gene id: 1318743:PU02_RS04825
uniprot id: A0A0M4LK76
names: Similarity
messages: Belongs to the RecJ family.

1318743:PU02 RS02305
gene id: 1318743:PU02_RS02305
uniprot id: A0A0M3T2T7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1318743:PU02 RS02485
gene id: 1318743:PU02_RS02485
uniprot id: A0A0M4M5J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1318743:PU02 RS03895
gene id: 1318743:PU02_RS03895
uniprot id: A0A0M4M652
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1318743:PU02 RS02145
gene id: 1318743:PU02_RS02145
uniprot id: A0A0M4LI18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1318743:PU02 RS06260
gene id: 1318743:PU02_RS06260
uniprot id: A0A0M3T377
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1318743:PU02 RS04210
gene id: 1318743:PU02_RS04210
uniprot id: A0A0M4M698
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

1318743:PU02 RS05705
gene id: 1318743:PU02_RS05705
uniprot id: A0A0M5KST4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1318743:PU02 RS03890
gene id: 1318743:PU02_RS03890
uniprot id: A0A0M3T2Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1318743:PU02 RS00130
gene id: 1318743:PU02_RS00130
uniprot id: A0A0M5KS88
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1318743:PU02 RS03795
gene id: 1318743:PU02_RS03795
uniprot id: A0A0M3T2X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1318743:PU02 RS05890
gene id: 1318743:PU02_RS05890
uniprot id: A0A0M4M6Z6
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1318743:PU02 RS03860
gene id: 1318743:PU02_RS03860
uniprot id: A0A0M3T304
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1318743:PU02 RS05595
gene id: 1318743:PU02_RS05595
uniprot id: A0A0M4LJH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1318743:PU02 RS02500
gene id: 1318743:PU02_RS02500
uniprot id: A0A0M3T2U5
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1318743:PU02 RS01690
gene id: 1318743:PU02_RS01690
uniprot id: A0A0M4LHV2
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1318743:PU02 RS02595
gene id: 1318743:PU02_RS02595
uniprot id: A0A0M4M5K9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1318743:PU02 RS00575
gene id: 1318743:PU02_RS00575
uniprot id: A0A0M4LIL2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1318743:PU02 RS06215
gene id: 1318743:PU02_RS06215
uniprot id: A0A0M3T375
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

1318743:PU02 RS05420
gene id: 1318743:PU02_RS05420
uniprot id: A0A0M4M6T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1318743:PU02 RS00325
gene id: 1318743:PU02_RS00325
uniprot id: A0A0M4LIJ2
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1318743:PU02 RS06165
gene id: 1318743:PU02_RS06165
uniprot id: A0A0M4LKQ1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1318743:PU02 RS05355
gene id: 1318743:PU02_RS05355
uniprot id: A0A0M5KZH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1318743:PU02 RS05985
gene id: 1318743:PU02_RS05985
uniprot id: A0A0M3T365
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1318743:PU02 RS01860
gene id: 1318743:PU02_RS01860
uniprot id: A0A0M4LHX7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cell inner membrane
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1318743:PU02 RS03805
gene id: 1318743:PU02_RS03805
uniprot id: A0A0M4M3L3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1318743:PU02 RS04160
gene id: 1318743:PU02_RS04160
uniprot id: A0A0M4LGT0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1318743:PU02 RS03835
gene id: 1318743:PU02_RS03835
uniprot id: A0A0M4LIS6
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1318743:PU02 RS03655
gene id: 1318743:PU02_RS03655
uniprot id: A0A0M4M615
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1318743:PU02 RS03935
gene id: 1318743:PU02_RS03935
uniprot id: A0A0M4LJU5
names: Subcellular Location Annotation
messages: Membrane

1318743:PU02 RS04535
gene id: 1318743:PU02_RS04535
uniprot id: A0A0M3T307
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1318743:PU02 RS05470
gene id: 1318743:PU02_RS05470
uniprot id: A0A0M4LKF3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1318743:PU02 RS00115
gene id: 1318743:PU02_RS00115
uniprot id: A0A0M4M216
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1318743:PU02 RS02620
gene id: 1318743:PU02_RS02620
uniprot id: A0A0M4M334
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1318743:PU02 RS03970
gene id: 1318743:PU02_RS03970
uniprot id: A0A0M4LGQ6
names: Similarity
messages: Belongs to the DEAD box helicase family.

1318743:PU02 RS04360
gene id: 1318743:PU02_RS04360
uniprot id: A0A0M4LT59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1318743:PU02 RS05900
gene id: 1318743:PU02_RS05900
uniprot id: A0A0M4LJL0
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the reversible phosphorylation of pyruvate and phosphate.

1318743:PU02 RS03565
gene id: 1318743:PU02_RS03565
uniprot id: A0A0M4LSU6
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1318743:PU02 RS02465
gene id: 1318743:PU02_RS02465
uniprot id: A0A0M4L7R4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1318743:PU02 RS03445
gene id: 1318743:PU02_RS03445
uniprot id: A0A0M4M3F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1318743:PU02 RS00085
gene id: 1318743:PU02_RS00085
uniprot id: A0A0M3T2H0
names: Similarity
messages: Belongs to the glutamine synthetase family.

1318743:PU02 RS04875
gene id: 1318743:PU02_RS04875
uniprot id: A0A0M4LTC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1318743:PU02 RS02310
gene id: 1318743:PU02_RS02310
uniprot id: A0A0M4LI42
names: Subcellular Location Annotation
messages: Cell outer membrane

1318743:PU02 RS04435
gene id: 1318743:PU02_RS04435
uniprot id: A0A0M4L8G0
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

1318743:PU02 RS06185
gene id: 1318743:PU02_RS06185
uniprot id: A0A0M3T397
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1318743:PU02 RS02425
gene id: 1318743:PU02_RS02425
uniprot id: A0A0M4LI53
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1318743:PU02 RS01800
gene id: 1318743:PU02_RS01800
uniprot id: A0A0M4M591
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

1318743:PU02 RS05425
gene id: 1318743:PU02_RS05425
uniprot id: A0A0M4LJF1
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1318743:PU02 RS02660
gene id: 1318743:PU02_RS02660
uniprot id: A0A0M4LG79
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.

1318743:PU02 RS05555
gene id: 1318743:PU02_RS05555
uniprot id: A0A0M3T347
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1318743:PU02 RS05125
gene id: 1318743:PU02_RS05125
uniprot id: U3NBL8
names: Similarity
messages: Belongs to the citrate synthase family.

1318743:PU02 RS02740
gene id: 1318743:PU02_RS02740
uniprot id: A0A0M5KWX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1318743:PU02 RS04120
gene id: 1318743:PU02_RS04120
uniprot id: A0A0M5L141
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1318743:PU02 RS04180
gene id: 1318743:PU02_RS04180
uniprot id: A0A0M5L160
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1318743:PU02 RS02265
gene id: 1318743:PU02_RS02265
uniprot id: A0A0M4L6J6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1318743:PU02 RS01300
gene id: 1318743:PU02_RS01300
uniprot id: A0A0M3T2M0
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1318743:PU02 RS00045
gene id: 1318743:PU02_RS00045
uniprot id: A0A0M5L0S5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1318743:PU02 RS01505
gene id: 1318743:PU02_RS01505
uniprot id: A0A0M4L7F8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1318743:PU02 RS05090
gene id: 1318743:PU02_RS05090
uniprot id: A0A0M4L8Q0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1318743:PU02 RS05980
gene id: 1318743:PU02_RS05980
uniprot id: A0A0M5L199
names: Similarity
messages: Belongs to the TlyA family.

1318743:PU02 RS02300
gene id: 1318743:PU02_RS02300
uniprot id: A0A0M4M5G9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1318743:PU02 RS04740
gene id: 1318743:PU02_RS04740
uniprot id: A0A0M3T315
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1318743:PU02 RS00835
gene id: 1318743:PU02_RS00835
uniprot id: A0A0M4M4W4
names: Similarity
messages: Belongs to the type III secretion exporter family.

1318743:PU02 RS01850
gene id: 1318743:PU02_RS01850
uniprot id: A0A0M4M5A0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1318743:PU02 RS04690
gene id: 1318743:PU02_RS04690
uniprot id: A0A0M3T313
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1318743:PU02 RS01815
gene id: 1318743:PU02_RS01815
uniprot id: A0A0M3T2R5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1318743:PU02 RS05630
gene id: 1318743:PU02_RS05630
uniprot id: A0A0M4L8W6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1318743:PU02 RS00060
gene id: 1318743:PU02_RS00060
uniprot id: A0A0M3T2J1
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).

1318743:PU02 RS02350
gene id: 1318743:PU02_RS02350
uniprot id: A0A0M3T2T9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1318743:PU02 RS04895
gene id: 1318743:PU02_RS04895
uniprot id: A0A0M4LK86
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1318743:PU02 RS04750
gene id: 1318743:PU02_RS04750
uniprot id: A0A0M4L8J6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1318743:PU02 RS01575
gene id: 1318743:PU02_RS01575
uniprot id: A0A0M4M560
names: Similarity
messages: Belongs to the UPF0335 family.

1318743:PU02 RS01920
gene id: 1318743:PU02_RS01920
uniprot id: A0A0M4LHY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1318743:PU02 RS01635
gene id: 1318743:PU02_RS01635
uniprot id: A0A0M4LHU2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1318743:PU02 RS05350
gene id: 1318743:PU02_RS05350
uniprot id: A0A0M4LKD9
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1318743:PU02 RS04255
gene id: 1318743:PU02_RS04255
uniprot id: A0A0M4L8D5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1318743:PU02 RS05840
gene id: 1318743:PU02_RS05840
uniprot id: A0A0M3T359
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1318743:PU02 RS00530
gene id: 1318743:PU02_RS00530
uniprot id: A0A0M4M4S1
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1318743:PU02 RS05950
gene id: 1318743:PU02_RS05950
uniprot id: A0A0M5KZJ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1318743:PU02 RS05690
gene id: 1318743:PU02_RS05690
uniprot id: A0A0M4L8X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1318743:PU02 RS04820
gene id: 1318743:PU02_RS04820
uniprot id: A0A0M4L8K5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1318743:PU02 RS04425
gene id: 1318743:PU02_RS04425
uniprot id: A0A0M4LT67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

1318743:PU02 RS06375
gene id: 1318743:PU02_RS06375
uniprot id: A0A0M5KX96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1318743:PU02 RS03995
gene id: 1318743:PU02_RS03995
uniprot id: A0A0M3T2Y7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1318743:PU02 RS04365
gene id: 1318743:PU02_RS04365
uniprot id: A0A0M3T324
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1318743:PU02 RS01655
gene id: 1318743:PU02_RS01655
uniprot id: A0A0M5KSE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1318743:PU02 RS03510
gene id: 1318743:PU02_RS03510
uniprot id: A0A0M3T2W6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1318743:PU02 RS04045
gene id: 1318743:PU02_RS04045
uniprot id: A0A0M3T2Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1318743:PU02 RS05385
gene id: 1318743:PU02_RS05385
uniprot id: A0A0M4LTI9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1318743:PU02 RS04880
gene id: 1318743:PU02_RS04880
uniprot id: A0A0M3T344
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1318743:PU02 RS06310
gene id: 1318743:PU02_RS06310
uniprot id: A0A0M3T3A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1318743:PU02 RS02360
gene id: 1318743:PU02_RS02360
uniprot id: A0A0M4M5H8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1318743:PU02 RS00660
gene id: 1318743:PU02_RS00660
uniprot id: A0A0M4LFF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1318743:PU02 RS04225
gene id: 1318743:PU02_RS04225
uniprot id: A0A0M4L772
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Oligomer of 12 subunits arranged in the form of two hexameric ring.

1318743:PU02 RS02165
gene id: 1318743:PU02_RS02165
uniprot id: A0A0M4LS98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1318743:PU02 RS04325
gene id: 1318743:PU02_RS04325
uniprot id: A0A0M4LK01
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1318743:PU02 RS05345
gene id: 1318743:PU02_RS05345
uniprot id: A0A0M4L8T1
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1318743:PU02 RS00100
gene id: 1318743:PU02_RS00100
uniprot id: A0A0M4L5T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1318743:PU02 RS00550
gene id: 1318743:PU02_RS00550
uniprot id: A0A0M3T2I8
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1318743:PU02 RS05915
gene id: 1318743:PU02_RS05915
uniprot id: A0A0M4L7S7
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1318743:PU02 RS03675
gene id: 1318743:PU02_RS03675
uniprot id: A0A0M5KSL7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1318743:PU02 RS03240
gene id: 1318743:PU02_RS03240
uniprot id: A0A0M3T2V4
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

1318743:PU02 RS01430
gene id: 1318743:PU02_RS01430
uniprot id: A0A0M5KUC0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1318743:PU02 RS04815
gene id: 1318743:PU02_RS04815
uniprot id: A0A0M3T342
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1318743:PU02 RS02545
gene id: 1318743:PU02_RS02545
uniprot id: A0A0M3T2U7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1318743:PU02 RS03925
gene id: 1318743:PU02_RS03925
uniprot id: A0A0M4L893
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1318743:PU02 RS00715
gene id: 1318743:PU02_RS00715
uniprot id: A0A0M3T2L7
names: Similarity
messages: Belongs to the MotB family.

1318743:PU02 RS04485
gene id: 1318743:PU02_RS04485
uniprot id: A0A0M5L171
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1318743:PU02 RS04730
gene id: 1318743:PU02_RS04730
uniprot id: A0A0M4LTA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1318743:PU02 RS04380
gene id: 1318743:PU02_RS04380
uniprot id: A0A0M4L8F2
names: Similarity
messages: Belongs to the BolA/IbaG family.

1318743:PU02 RS02050
gene id: 1318743:PU02_RS02050
uniprot id: A0A0M4L6G7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

1318743:PU02 RS02080
gene id: 1318743:PU02_RS02080
uniprot id: A0A0M5KSG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1318743:PU02 RS04285
gene id: 1318743:PU02_RS04285
uniprot id: A0A0M4LGU7
names: Similarity
messages: Belongs to the FBPase class 2 family.

1318743:PU02 RS06130
gene id: 1318743:PU02_RS06130
uniprot id: A0A0M3T395
names: Similarity
messages: Belongs to the aspartokinase family.

1318743:PU02 RS05575
gene id: 1318743:PU02_RS05575
uniprot id: A0A0M3T372
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1318743:PU02 RS02030
gene id: 1318743:PU02_RS02030
uniprot id: A0A0M4M5C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

1318743:PU02 RS04530
gene id: 1318743:PU02_RS04530
uniprot id: A0A0M4L7A6
names: Similarity
messages: Belongs to the UPF0758 family.

1318743:PU02 RS04650
gene id: 1318743:PU02_RS04650
uniprot id: A0A0M4LJ40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1318743:PU02 RS00915
gene id: 1318743:PU02_RS00915
uniprot id: A0A0M3T2M5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1318743:PU02 RS04600
gene id: 1318743:PU02_RS04600
uniprot id: A0A0M4LT95
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1318743:PU02 RS03690
gene id: 1318743:PU02_RS03690
uniprot id: A0A0M3T2X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1318743:PU02 RS05290
gene id: 1318743:PU02_RS05290
uniprot id: A0A0M4LT09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1318743:PU02 RS00560
gene id: 1318743:PU02_RS00560
uniprot id: A0A0M4M276
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1318743:PU02 RS04495
gene id: 1318743:PU02_RS04495
uniprot id: A0A0M4M3V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1318743:PU02 RS06270
gene id: 1318743:PU02_RS06270
uniprot id: A0A0M4M4K4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1318743:PU02 RS02480
gene id: 1318743:PU02_RS02480
uniprot id: A0A0M3T2S2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1318743:PU02 RS05495
gene id: 1318743:PU02_RS05495
uniprot id: A0A0M4LH78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1318743:PU02 RS02700
gene id: 1318743:PU02_RS02700
uniprot id: A0A0M5KSH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1318743:PU02 RS05670
gene id: 1318743:PU02_RS05670
uniprot id: A0A0M4L7P9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1318743:PU02 RS04475
gene id: 1318743:PU02_RS04475
uniprot id: A0A0M4L798
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1318743:PU02 RS02430
gene id: 1318743:PU02_RS02430
uniprot id: A0A0M3T2S0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1318743:PU02 RS06315
gene id: 1318743:PU02_RS06315
uniprot id: A0A0M5L1D4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1318743:PU02 RS04385
gene id: 1318743:PU02_RS04385
uniprot id: A0A0M4LK11
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1318743:PU02 RS06190
gene id: 1318743:PU02_RS06190
uniprot id: A0A0M4LJQ2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1318743:PU02 RS03660
gene id: 1318743:PU02_RS03660
uniprot id: A0A0M4LIQ2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1318743:PU02 RS05580
gene id: 1318743:PU02_RS05580
uniprot id: A0A0M4L8W0
names: Similarity
messages: Belongs to the fabD family.

1318743:PU02 RS04465
gene id: 1318743:PU02_RS04465
uniprot id: A0A0M4LJ09
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1318743:PU02 RS02115
gene id: 1318743:PU02_RS02115
uniprot id: A0A0M4M2V3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1318743:PU02 RS04455
gene id: 1318743:PU02_RS04455
uniprot id: A0A0M4M6D8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1318743:PU02 RS04195
gene id: 1318743:PU02_RS04195
uniprot id: A0A0M3T2Z3
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1318743:PU02 RS02470
gene id: 1318743:PU02_RS02470
uniprot id: A0A0M4LJ96
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1318743:PU02 RS06325
gene id: 1318743:PU02_RS06325
uniprot id: A0A0M4L957
names: Similarity
messages: Belongs to the YggT family.

1318743:PU02 RS03595
gene id: 1318743:PU02_RS03595
uniprot id: A0A0M5KSK8
names: Subcellular Location Annotation
messages: Mitochondrion

1318743:PU02 RS05195
gene id: 1318743:PU02_RS05195
uniprot id: A0A0M5KX54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1318743:PU02 RS02185
gene id: 1318743:PU02_RS02185
uniprot id: A0A0M4L7N2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1318743:PU02 RS01455
gene id: 1318743:PU02_RS01455
uniprot id: A0A0M3T2P9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

1318743:PU02 RS01215
gene id: 1318743:PU02_RS01215
uniprot id: A0A0M5L0U3
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1318743:PU02 RS03945
gene id: 1318743:PU02_RS03945
uniprot id: A0A0M5KSM7
names: Similarity
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.

1318743:PU02 RS04400
gene id: 1318743:PU02_RS04400
uniprot id: A0A0M4M6C7
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1318743:PU02 RS03885
gene id: 1318743:PU02_RS03885
uniprot id: A0A0M5KSL8
names: Subcellular Location Annotation
messages: Membrane

1318743:PU02 RS03990
gene id: 1318743:PU02_RS03990
uniprot id: A0A0M5KSM6
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1318743:PU02 RS02940
gene id: 1318743:PU02_RS02940
uniprot id: A0A0M4L7X0
names: Similarity
messages: Belongs to the RelE toxin family.

1318743:PU02 RS00770
gene id: 1318743:PU02_RS00770
uniprot id: A0A0M5KSA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

1318743:PU02 RS04065
gene id: 1318743:PU02_RS04065
uniprot id: A0A0M3T312
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1318743:PU02 RS00795
gene id: 1318743:PU02_RS00795
uniprot id: A0A0M3T2J8
names: Subcellular Location Annotation
messages: Cytoplasm

1318743:PU02 RS03340
gene id: 1318743:PU02_RS03340
uniprot id: A0A0M4L817
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1318743:PU02 RS03580
gene id: 1318743:PU02_RS03580
uniprot id: A0A0M3T2Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1318743:PU02 RS02800
gene id: 1318743:PU02_RS02800
uniprot id: A0A0M3T2T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1318743:PU02 RS02780
gene id: 1318743:PU02_RS02780
uniprot id: A0A0M4LI97
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1318743:PU02 RS06320
gene id: 1318743:PU02_RS06320
uniprot id: A0A0M4M4L2
names: Similarity
messages: Belongs to the UPF0235 family.

1318743:PU02 RS02995
gene id: 1318743:PU02_RS02995
uniprot id: A0A0M4L7X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1318743:PU02 RS05110
gene id: 1318743:PU02_RS05110
uniprot id: A0A0M4LJA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1318743:PU02 RS03910
gene id: 1318743:PU02_RS03910
uniprot id: A0A0M3T306
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1318743:PU02 RS01290
gene id: 1318743:PU02_RS01290
uniprot id: A0A0M4M525
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1318743:PU02 RS00650
gene id: 1318743:PU02_RS00650
uniprot id: A0A0M4LHF4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1318743:PU02 RS02395
gene id: 1318743:PU02_RS02395
uniprot id: A0A0M5L102
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1318743:PU02 RS01745
gene id: 1318743:PU02_RS01745
uniprot id: A0A0M4LHW1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

1318743:PU02 RS04165
gene id: 1318743:PU02_RS04165
uniprot id: A0A0M3T316
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1318743:PU02 RS04185
gene id: 1318743:PU02_RS04185
uniprot id: A0A0M4M3R1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1318743:PU02 RS04170
gene id: 1318743:PU02_RS04170
uniprot id: A0A0M4L768
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1318743:PU02 RS00985
gene id: 1318743:PU02_RS00985
uniprot id: A0A0M5KSC7
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

1318743:PU02 RS05720
gene id: 1318743:PU02_RS05720
uniprot id: A0A0M4LJI6
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

1318743:PU02 RS05525
gene id: 1318743:PU02_RS05525
uniprot id: A0A0M3T370
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1318743:PU02 RS00235
gene id: 1318743:PU02_RS00235
uniprot id: A0A0M5KU90
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1318743:PU02 RS06105
gene id: 1318743:PU02_RS06105
uniprot id: A0A0M4LKP3
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1318743:PU02 RS01625
gene id: 1318743:PU02_RS01625
uniprot id: A0A0M4M568
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1318743:PU02 RS04200
gene id: 1318743:PU02_RS04200
uniprot id: A0A0M4LJY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1318743:PU02 RS05100
gene id: 1318743:PU02_RS05100
uniprot id: A0A0M5KSR4
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1318743:PU02 RS00035
gene id: 1318743:PU02_RS00035
uniprot id: A0A0M3T2G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1318743:PU02 RS03555
gene id: 1318743:PU02_RS03555
uniprot id: A0A0M4L6Z8
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1318743:PU02 RS05190
gene id: 1318743:PU02_RS05190
uniprot id: A0A0M4L7I2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1318743:PU02 RS04710
gene id: 1318743:PU02_RS04710
uniprot id: A0A0M3T338
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Cytoplasm
messages: Homodimer.

1318743:PU02 RS02635
gene id: 1318743:PU02_RS02635
uniprot id: A0A0M4LJB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Membrane

1318743:PU02 RS03005
gene id: 1318743:PU02_RS03005
uniprot id: A0A0M4LJG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1318743:PU02 RS04700
gene id: 1318743:PU02_RS04700
uniprot id: A0A0M5KZE9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1318743:PU02 RS03915
gene id: 1318743:PU02_RS03915
uniprot id: A0A0M4LSZ4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1318743:PU02 RS02105
gene id: 1318743:PU02_RS02105
uniprot id: A0A0M5L0Z2
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1318743:PU02 RS02705
gene id: 1318743:PU02_RS02705
uniprot id: A0A0M3T2T2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1318743:PU02 RS02460
gene id: 1318743:PU02_RS02460
uniprot id: A0A0M4M311
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1318743:PU02 RS01030
gene id: 1318743:PU02_RS01030
uniprot id: A0A1V0PNE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1318743:PU02 RS04110
gene id: 1318743:PU02_RS04110
uniprot id: A0A0M4LT16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1318743:PU02 RS03825
gene id: 1318743:PU02_RS03825
uniprot id: A0A0M5KSM2
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1318743:PU02 RS00585
gene id: 1318743:PU02_RS00585
uniprot id: A0A0M4M4T0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1318743:PU02 RS04785
gene id: 1318743:PU02_RS04785
uniprot id: A0A0M3T317
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1318743:PU02 RS05160
gene id: 1318743:PU02_RS05160
uniprot id: A0A0M5KSR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1318743:PU02 RS02200
gene id: 1318743:PU02_RS02200
uniprot id: A0A0M4LI29
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1318743:PU02 RS04090
gene id: 1318743:PU02_RS04090
uniprot id: A0A0M4LIV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1318743:PU02 RS04020
gene id: 1318743:PU02_RS04020
uniprot id: A0A0M5KTS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1318743:PU02 RS04635
gene id: 1318743:PU02_RS04635
uniprot id: A0A0M5KTU6
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1318743:PU02 RS04305
gene id: 1318743:PU02_RS04305
uniprot id: A0A0M5KSN6
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1318743:PU02 RS01760
gene id: 1318743:PU02_RS01760
uniprot id: A0A0M4L6D1
names: Cofactor
names: Function
names: Subunit
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1318743:PU02 RS04245
gene id: 1318743:PU02_RS04245
uniprot id: A0A0M3T2Z5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1318743:PU02 RS06085
gene id: 1318743:PU02_RS06085
uniprot id: A0A0M4L7U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1318743:PU02 RS05485
gene id: 1318743:PU02_RS05485
uniprot id: A0A0M3T368
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1318743:PU02 RS00905
gene id: 1318743:PU02_RS00905
uniprot id: U3N9Z5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1318743:PU02 RS00135
gene id: 1318743:PU02_RS00135
uniprot id: A0A0M3T2H2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

1318743:PU02 RS04545
gene id: 1318743:PU02_RS04545
uniprot id: A0A0M5KX34
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1318743:PU02 RS02535
gene id: 1318743:PU02_RS02535
uniprot id: A0A0M4LJA3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1318743:PU02 RS04990
gene id: 1318743:PU02_RS04990
uniprot id: A0A0M4LJ93
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1318743:PU02 RS03840
gene id: 1318743:PU02_RS03840
uniprot id: A0A0M3T2Y1
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1318743:PU02 RS04070
gene id: 1318743:PU02_RS04070
uniprot id: A0A0M4L8B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1318743:PU02 RS05875
gene id: 1318743:PU02_RS05875
uniprot id: A0A0M4LKL1
names: Similarity
messages: Belongs to the SufE family.

1318743:PU02 RS04970
gene id: 1318743:PU02_RS04970
uniprot id: A0A0M4LK93
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1318743:PU02 RS01840
gene id: 1318743:PU02_RS01840
uniprot id: A0A0M3T2P4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1318743:PU02 RS01550
gene id: 1318743:PU02_RS01550
uniprot id: A0A0M4M2L6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1318743:PU02 RS06350
gene id: 1318743:PU02_RS06350
uniprot id: A0A0M4LJS8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1318743:PU02 RS04290
gene id: 1318743:PU02_RS04290
uniprot id: A0A0M4L780
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1318743:PU02 RS00160
gene id: 1318743:PU02_RS00160
uniprot id: A0A0M4L5U4
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1318743:PU02 RS05145
gene id: 1318743:PU02_RS05145
uniprot id: A0A0M4M452
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1318743:PU02 RS05405
gene id: 1318743:PU02_RS05405
uniprot id: A0A0M4L8T8
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1318743:PU02 RS05880
gene id: 1318743:PU02_RS05880
uniprot id: A0A0M5KTY8
names: Similarity
messages: Belongs to the ros/MucR family.

1318743:PU02 RS02450
gene id: 1318743:PU02_RS02450
uniprot id: A0A0M3T2U3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1318743:PU02 RS00830
gene id: 1318743:PU02_RS00830
uniprot id: A0A0M5KTH0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1318743:PU02 RS04745
gene id: 1318743:PU02_RS04745
uniprot id: A0A0M4M3Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1318743:PU02 RS05435
gene id: 1318743:PU02_RS05435
uniprot id: A0A0M3T366
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1318743:PU02 RS00685
gene id: 1318743:PU02_RS00685
uniprot id: A0A0M4M293
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1318743:PU02 RS05250
gene id: 1318743:PU02_RS05250
uniprot id: U3N9F2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1318743:PU02 RS04270
gene id: 1318743:PU02_RS04270
uniprot id: A0A0M4M6A8
names: Subcellular Location Annotation
messages: Membrane

1318743:PU02 RS06265
gene id: 1318743:PU02_RS06265
uniprot id: A0A0M4LTV0
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1318743:PU02 RS03120
gene id: 1318743:PU02_RS03120
uniprot id: A0A0M4LJI1
names: Subcellular Location Annotation
messages: Membrane

1318743:PU02 RS04705
gene id: 1318743:PU02_RS04705
uniprot id: A0A0M4M6H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1318743:PU02 RS03350
gene id: 1318743:PU02_RS03350
uniprot id: A0A0M5KSK4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1318743:PU02 RS05120
gene id: 1318743:PU02_RS05120
uniprot id: A0A0M4LH39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1318743:PU02 RS06195
gene id: 1318743:PU02_RS06195
uniprot id: A0A0M4LHG9
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1318743:PU02 RS05725
gene id: 1318743:PU02_RS05725
uniprot id: A0A0M4LHB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1318743:PU02 RS02770
gene id: 1318743:PU02_RS02770
uniprot id: A0A0M4M5N3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1318743:PU02 RS05990
gene id: 1318743:PU02_RS05990
uniprot id: A0A0M4M4G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1318743:PU02 RS05665
gene id: 1318743:PU02_RS05665
uniprot id: A0A0M3T376
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1318743:PU02 RS01325
gene id: 1318743:PU02_RS01325
uniprot id: A0A0M3T2P3
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1318743:PU02 RS06060
gene id: 1318743:PU02_RS06060
uniprot id: A0A0M5KST9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1318743:PU02 RS04300
gene id: 1318743:PU02_RS04300
uniprot id: A0A0M4LT44
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1318743:PU02 RS02750
gene id: 1318743:PU02_RS02750
uniprot id: A0A0M4L7U9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Cytoplasm
messages: Homotetramer.

1318743:PU02 RS06090
gene id: 1318743:PU02_RS06090
uniprot id: A0A0M4LTS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1318743:PU02 RS04050
gene id: 1318743:PU02_RS04050
uniprot id: A0A0M4LT09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1318743:PU02 RS03810
gene id: 1318743:PU02_RS03810
uniprot id: A0A0M3T302
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein.

1318743:PU02 RS02275
gene id: 1318743:PU02_RS02275
uniprot id: A0A0M5KUF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1318743:PU02 RS02135
gene id: 1318743:PU02_RS02135
uniprot id: A0A0M5KSF6
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1318743:PU02 RS06370
gene id: 1318743:PU02_RS06370
uniprot id: A0A0M4LTW4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1318743:PU02 RS03930
gene id: 1318743:PU02_RS03930
uniprot id: A0A0M3T2Y5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1318743:PU02 RS03775
gene id: 1318743:PU02_RS03775
uniprot id: A0A0M4M633
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1318743:PU02 RS01845
gene id: 1318743:PU02_RS01845
uniprot id: A0A0M4LJ25
names: Similarity
messages: Belongs to the SDHAF4 family.

1318743:PU02 RS01650
gene id: 1318743:PU02_RS01650
uniprot id: A0A0M4LS28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1318743:PU02 RS02385
gene id: 1318743:PU02_RS02385
uniprot id: A0A0M3T2R8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1318743:PU02 RS01670
gene id: 1318743:PU02_RS01670
uniprot id: A0A0M4L7H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1318743:PU02 RS06230
gene id: 1318743:PU02_RS06230
uniprot id: A0A0M4LKR3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1318743:PU02 RS04725
gene id: 1318743:PU02_RS04725
uniprot id: A0A0M4L7C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1318743:PU02 RS05395
gene id: 1318743:PU02_RS05395
uniprot id: A0A0M5L179
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1318743:PU02 RS03425
gene id: 1318743:PU02_RS03425
uniprot id: A0A0M3T2Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1318743:PU02 RS02060
gene id: 1318743:PU02_RS02060
uniprot id: A0A0M5L0X6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1318743:PU02 RS05430
gene id: 1318743:PU02_RS05430
uniprot id: A0A0M4LH70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1318743:PU02 RS01425
gene id: 1318743:PU02_RS01425
uniprot id: A0A0M4L689
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1318743:PU02 RS03700
gene id: 1318743:PU02_RS03700
uniprot id: A0A0M5KTR4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1318743:PU02 RS06245
gene id: 1318743:PU02_RS06245
uniprot id: A0A0M4M741
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Probably responsible for the translocation of the substrate across the membrane.
messages: Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

1318743:PU02 RS01285
gene id: 1318743:PU02_RS01285
uniprot id: A0A0M5KSC8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

1318743:PU02 RS04395
gene id: 1318743:PU02_RS04395
uniprot id: A0A0M3T301
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1318743:PU02 RS02645
gene id: 1318743:PU02_RS02645
uniprot id: A0A0M4M5L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1318743:PU02 RS05500
gene id: 1318743:PU02_RS05500
uniprot id: A0A0M4L7L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1318743:PU02 RS04915
gene id: 1318743:PU02_RS04915
uniprot id: A0A0M3T321
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

1318743:PU02 RS00750
gene id: 1318743:PU02_RS00750
uniprot id: A0A0M4M2A0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1318743:PU02 RS00910
gene id: 1318743:PU02_RS00910
uniprot id: A0A0M4LFI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1318743:PU02 RS04275
gene id: 1318743:PU02_RS04275
uniprot id: A0A0M4LIY1
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1318743:PU02 RS00020
gene id: 1318743:PU02_RS00020
uniprot id: A0A0M4LF78
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1318743:PU02 RS03365
gene id: 1318743:PU02_RS03365
uniprot id: A0A0M3T2W0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1318743:PU02 RS06075
gene id: 1318743:PU02_RS06075
uniprot id: A0A0M3T369
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1318743:PU02 RS04215
gene id: 1318743:PU02_RS04215
uniprot id: A0A0M3T318
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1318743:PU02 RS04060
gene id: 1318743:PU02_RS04060
uniprot id: A0A0M4M3P4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1318743:PU02 RS05710
gene id: 1318743:PU02_RS05710
uniprot id: A0A0M4M6X1
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1318743:PU02 RS03520
gene id: 1318743:PU02_RS03520
uniprot id: A0A0M4L838
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

1318743:PU02 RS04830
gene id: 1318743:PU02_RS04830
uniprot id: A0A0M5KSQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1318743:PU02 RS05995
gene id: 1318743:PU02_RS05995
uniprot id: A0A0M4L914
names: Function
names: Similarity
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1318743:PU02 RS05565
gene id: 1318743:PU02_RS05565
uniprot id: A0A0M5KSS8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1318743:PU02 RS02410
gene id: 1318743:PU02_RS02410
uniprot id: A0A0M4LJ89
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1318743:PU02 RS02320
gene id: 1318743:PU02_RS02320
uniprot id: A0A0M4L6K4
names: Similarity
messages: Belongs to the ABC transporter superfamily.