1307839:L21SP5 RS15255
gene id: 1307839:L21SP5_RS15255
uniprot id: A0A0S2I3A9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS06545
gene id: 1307839:L21SP5_RS06545
uniprot id: A0A0S2HYS5
names: Subcellular Location Annotation
messages: Secreted

1307839:L21SP5 RS11595
gene id: 1307839:L21SP5_RS11595
uniprot id: A0A0S2I148
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1307839:L21SP5 RS06750
gene id: 1307839:L21SP5_RS06750
uniprot id: A0A0S2HY46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

1307839:L21SP5 RS13885
gene id: 1307839:L21SP5_RS13885
uniprot id: A0A0S2I2K3
names: Similarity
messages: Belongs to the SusD family.

1307839:L21SP5 RS14770
gene id: 1307839:L21SP5_RS14770
uniprot id: A0A0S2I314
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1307839:L21SP5 RS06245
gene id: 1307839:L21SP5_RS06245
uniprot id: A0A0S2HXX8
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS07080
gene id: 1307839:L21SP5_RS07080
uniprot id: A0A0S2HY80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

1307839:L21SP5 RS14610
gene id: 1307839:L21SP5_RS14610
uniprot id: A0A0S2I3M8
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1307839:L21SP5 RS00235
gene id: 1307839:L21SP5_RS00235
uniprot id: A0A0S2HUJ9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1307839:L21SP5 RS13530
gene id: 1307839:L21SP5_RS13530
uniprot id: A0A0S2I1T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1307839:L21SP5 RS13055
gene id: 1307839:L21SP5_RS13055
uniprot id: A0A0S2I1Y8
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1307839:L21SP5 RS05125
gene id: 1307839:L21SP5_RS05125
uniprot id: A0A0S2HXC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1307839:L21SP5 RS19190
gene id: 1307839:L21SP5_RS19190
uniprot id: A0A0S2I5I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1307839:L21SP5 RS08260
gene id: 1307839:L21SP5_RS08260
uniprot id: A0A0S2HZ89
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

1307839:L21SP5 RS11435
gene id: 1307839:L21SP5_RS11435
uniprot id: A0A0S2I125
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1307839:L21SP5 RS08965
gene id: 1307839:L21SP5_RS08965
uniprot id: A0A0S2HZK0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1307839:L21SP5 RS10980
gene id: 1307839:L21SP5_RS10980
uniprot id: A0A0S2I0D1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1307839:L21SP5 RS12385
gene id: 1307839:L21SP5_RS12385
uniprot id: A0A0S2I1G6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1307839:L21SP5 RS05290
gene id: 1307839:L21SP5_RS05290
uniprot id: A0A0S2HXF9
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS03775
gene id: 1307839:L21SP5_RS03775
uniprot id: A0A0S2HWU0
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS12185
gene id: 1307839:L21SP5_RS12185
uniprot id: A0A0S2I1E1
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1307839:L21SP5 RS11085
gene id: 1307839:L21SP5_RS11085
uniprot id: A0A0S2I0S1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1307839:L21SP5 RS02255
gene id: 1307839:L21SP5_RS02255
uniprot id: A0A0S2HVP6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

1307839:L21SP5 RS15005
gene id: 1307839:L21SP5_RS15005
uniprot id: A0A0S2I391
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1307839:L21SP5 RS05130
gene id: 1307839:L21SP5_RS05130
uniprot id: A0A0S2HXC9
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS14950
gene id: 1307839:L21SP5_RS14950
uniprot id: A0A0S2I330
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1307839:L21SP5 RS19360
gene id: 1307839:L21SP5_RS19360
uniprot id: A0A0S2I5F3
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1307839:L21SP5 RS05585
gene id: 1307839:L21SP5_RS05585
uniprot id: A0A0S2HYA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1307839:L21SP5 RS10860
gene id: 1307839:L21SP5_RS10860
uniprot id: A0A0S2I0L7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1307839:L21SP5 RS13325
gene id: 1307839:L21SP5_RS13325
uniprot id: A0A0S2I1U0
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS01715
gene id: 1307839:L21SP5_RS01715
uniprot id: A0A0S2HVB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

1307839:L21SP5 RS10880
gene id: 1307839:L21SP5_RS10880
uniprot id: A0A0S2I0J7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1307839:L21SP5 RS14405
gene id: 1307839:L21SP5_RS14405
uniprot id: A0A0S2I294
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1307839:L21SP5 RS13090
gene id: 1307839:L21SP5_RS13090
uniprot id: A0A0S2I229
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

1307839:L21SP5 RS03580
gene id: 1307839:L21SP5_RS03580
uniprot id: A0A0S2HWJ7
names: Similarity
messages: Belongs to the peptidase C40 family.

1307839:L21SP5 RS08105
gene id: 1307839:L21SP5_RS08105
uniprot id: A0A0S2HYY8
names: Similarity
messages: Belongs to the DEAD box helicase family.

1307839:L21SP5 RS15770
gene id: 1307839:L21SP5_RS15770
uniprot id: A0A0S2I3H1
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1307839:L21SP5 RS04810
gene id: 1307839:L21SP5_RS04810
uniprot id: A0A0S2HXE8
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

1307839:L21SP5 RS04600
gene id: 1307839:L21SP5_RS04600
uniprot id: A0A0S2HWZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1307839:L21SP5 RS15020
gene id: 1307839:L21SP5_RS15020
uniprot id: A0A0S2I2X5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1307839:L21SP5 RS13890
gene id: 1307839:L21SP5_RS13890
uniprot id: A0A0S2I2M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1307839:L21SP5 RS06020
gene id: 1307839:L21SP5_RS06020
uniprot id: A0A0S2HXQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1307839:L21SP5 RS04905
gene id: 1307839:L21SP5_RS04905
uniprot id: A0A0S2HX86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1307839:L21SP5 RS14190
gene id: 1307839:L21SP5_RS14190
uniprot id: A0A0S2I2N2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS04840
gene id: 1307839:L21SP5_RS04840
uniprot id: A0A0S2HX42
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1307839:L21SP5 RS19260
gene id: 1307839:L21SP5_RS19260
uniprot id: A0A0S2I5R8
names: Similarity
messages: Belongs to the alkaline phosphatase family.

1307839:L21SP5 RS16825
gene id: 1307839:L21SP5_RS16825
uniprot id: A0A0S2I422
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1307839:L21SP5 RS08975
gene id: 1307839:L21SP5_RS08975
uniprot id: A0A0S2HZM1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1307839:L21SP5 RS01800
gene id: 1307839:L21SP5_RS01800
uniprot id: A0A0S2HVJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1307839:L21SP5 RS11950
gene id: 1307839:L21SP5_RS11950
uniprot id: A0A0S2I105
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1307839:L21SP5 RS05490
gene id: 1307839:L21SP5_RS05490
uniprot id: A0A0S2HXJ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1307839:L21SP5 RS06380
gene id: 1307839:L21SP5_RS06380
uniprot id: A0A0S2HXV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1307839:L21SP5 RS14400
gene id: 1307839:L21SP5_RS14400
uniprot id: A0A0S2I2L8
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS19150
gene id: 1307839:L21SP5_RS19150
uniprot id: A0A0S2I5P2
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Belongs to the spermidine/spermine synthase family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Homodimer or homotetramer.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS11335
gene id: 1307839:L21SP5_RS11335
uniprot id: A0A0S2I0W1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS07520
gene id: 1307839:L21SP5_RS07520
uniprot id: A0A0S2HYX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1307839:L21SP5 RS14605
gene id: 1307839:L21SP5_RS14605
uniprot id: A0A0S2I315
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1307839:L21SP5 RS13435
gene id: 1307839:L21SP5_RS13435
uniprot id: A0A0S2I288
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

1307839:L21SP5 RS09405
gene id: 1307839:L21SP5_RS09405
uniprot id: A0A0S2HZU9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS06250
gene id: 1307839:L21SP5_RS06250
uniprot id: A0A0S2HXX4
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1307839:L21SP5 RS13160
gene id: 1307839:L21SP5_RS13160
uniprot id: A0A0S2I1M7
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS17060
gene id: 1307839:L21SP5_RS17060
uniprot id: A0A0S2I495
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1307839:L21SP5 RS05155
gene id: 1307839:L21SP5_RS05155
uniprot id: A0A0S2HY34
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

1307839:L21SP5 RS07395
gene id: 1307839:L21SP5_RS07395
uniprot id: A0A0S2HYE4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1307839:L21SP5 RS06215
gene id: 1307839:L21SP5_RS06215
uniprot id: A0A0S2HY22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS17200
gene id: 1307839:L21SP5_RS17200
uniprot id: A0A0S2I434
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1307839:L21SP5 RS08120
gene id: 1307839:L21SP5_RS08120
uniprot id: A0A0S2HZ15
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1307839:L21SP5 RS11620
gene id: 1307839:L21SP5_RS11620
uniprot id: A0A0S2I1T0
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1307839:L21SP5 RS15275
gene id: 1307839:L21SP5_RS15275
uniprot id: A0A0S2I325
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1307839:L21SP5 RS10965
gene id: 1307839:L21SP5_RS10965
uniprot id: A0A0S2I0Q5
names: Similarity
messages: Belongs to the UPF0045 family.

1307839:L21SP5 RS14585
gene id: 1307839:L21SP5_RS14585
uniprot id: A0A0S2I2V7
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS17310
gene id: 1307839:L21SP5_RS17310
uniprot id: A0A0S2I4I2
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS02460
gene id: 1307839:L21SP5_RS02460
uniprot id: A0A0S2HVS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1307839:L21SP5 RS16505
gene id: 1307839:L21SP5_RS16505
uniprot id: A0A0S2I447
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1307839:L21SP5 RS01755
gene id: 1307839:L21SP5_RS01755
uniprot id: A0A0S2HVE1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1307839:L21SP5 RS16295
gene id: 1307839:L21SP5_RS16295
uniprot id: A0A0S2I3X6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1307839:L21SP5 RS11375
gene id: 1307839:L21SP5_RS11375
uniprot id: A0A0S2I0W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1307839:L21SP5 RS15610
gene id: 1307839:L21SP5_RS15610
uniprot id: A0A0S2I3E8
names: Similarity
messages: Belongs to the UPF0175 family.

1307839:L21SP5 RS16380
gene id: 1307839:L21SP5_RS16380
uniprot id: A0A0S2I4M3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS14835
gene id: 1307839:L21SP5_RS14835
uniprot id: A0A0S2I2M6
names: Similarity
messages: Belongs to the IMPACT family.

1307839:L21SP5 RS15310
gene id: 1307839:L21SP5_RS15310
uniprot id: A0A0S2I2T4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1307839:L21SP5 RS08610
gene id: 1307839:L21SP5_RS08610
uniprot id: A0A0S2HZG7
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1307839:L21SP5 RS10855
gene id: 1307839:L21SP5_RS10855
uniprot id: A0A0S2I0H4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1307839:L21SP5 RS09315
gene id: 1307839:L21SP5_RS09315
uniprot id: A0A0S2I0K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1307839:L21SP5 RS11590
gene id: 1307839:L21SP5_RS11590
uniprot id: A0A0S2I127
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1307839:L21SP5 RS19100
gene id: 1307839:L21SP5_RS19100
uniprot id: A0A0S2I5P1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1307839:L21SP5 RS00010
gene id: 1307839:L21SP5_RS00010
uniprot id: A0A0S2HUP3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1307839:L21SP5 RS09885
gene id: 1307839:L21SP5_RS09885
uniprot id: A0A0S2I0B7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1307839:L21SP5 RS12315
gene id: 1307839:L21SP5_RS12315
uniprot id: A0A0S2I1E5
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1307839:L21SP5 RS11830
gene id: 1307839:L21SP5_RS11830
uniprot id: A0A0S2I131
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1307839:L21SP5 RS07645
gene id: 1307839:L21SP5_RS07645
uniprot id: A0A0S2HYP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1307839:L21SP5 RS11065
gene id: 1307839:L21SP5_RS11065
uniprot id: A0A0S2I0L2
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS05830
gene id: 1307839:L21SP5_RS05830
uniprot id: A0A0S2HXQ3
names: Similarity
messages: Belongs to the peptidase S8 family.

1307839:L21SP5 RS16845
gene id: 1307839:L21SP5_RS16845
uniprot id: A0A0S2I3J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1307839:L21SP5 RS01665
gene id: 1307839:L21SP5_RS01665
uniprot id: A0A0S2HVC2
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1307839:L21SP5 RS08840
gene id: 1307839:L21SP5_RS08840
uniprot id: A0A0S2HZJ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1307839:L21SP5 RS11175
gene id: 1307839:L21SP5_RS11175
uniprot id: A0A0S2I0T4
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1307839:L21SP5 RS17645
gene id: 1307839:L21SP5_RS17645
uniprot id: A0A0S2I4R1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1307839:L21SP5 RS19205
gene id: 1307839:L21SP5_RS19205
uniprot id: A0A0S2I581
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1307839:L21SP5 RS13765
gene id: 1307839:L21SP5_RS13765
uniprot id: A0A0S2I287
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1307839:L21SP5 RS18750
gene id: 1307839:L21SP5_RS18750
uniprot id: A0A0S2I5G7
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1307839:L21SP5 RS11850
gene id: 1307839:L21SP5_RS11850
uniprot id: A0A0S2I173
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1307839:L21SP5 RS12325
gene id: 1307839:L21SP5_RS12325
uniprot id: A0A0S2I1C8
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1307839:L21SP5 RS12250
gene id: 1307839:L21SP5_RS12250
uniprot id: A0A0S2I1H3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1307839:L21SP5 RS05755
gene id: 1307839:L21SP5_RS05755
uniprot id: A0A0S2HXN5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1307839:L21SP5 RS14330
gene id: 1307839:L21SP5_RS14330
uniprot id: A0A0S2I2M4
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1307839:L21SP5 RS07430
gene id: 1307839:L21SP5_RS07430
uniprot id: A0A0S2HYM0
names: Similarity
messages: Belongs to the SfsA family.

1307839:L21SP5 RS13725
gene id: 1307839:L21SP5_RS13725
uniprot id: A0A0S2I2H3
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS09370
gene id: 1307839:L21SP5_RS09370
uniprot id: A0A0S2HZQ4
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1307839:L21SP5 RS17105
gene id: 1307839:L21SP5_RS17105
uniprot id: A0A0S2I564
names: Similarity
messages: Belongs to the peptidase M16 family.

1307839:L21SP5 RS01490
gene id: 1307839:L21SP5_RS01490
uniprot id: A0A0S2HVB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1307839:L21SP5 RS05285
gene id: 1307839:L21SP5_RS05285
uniprot id: A0A0S2HXG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1307839:L21SP5 RS00035
gene id: 1307839:L21SP5_RS00035
uniprot id: A0A0S2HUC3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1307839:L21SP5 RS04500
gene id: 1307839:L21SP5_RS04500
uniprot id: A0A0S2HWV1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1307839:L21SP5 RS07055
gene id: 1307839:L21SP5_RS07055
uniprot id: A0A0S2HYA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1307839:L21SP5 RS17170
gene id: 1307839:L21SP5_RS17170
uniprot id: A0A0S2I3S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

1307839:L21SP5 RS10810
gene id: 1307839:L21SP5_RS10810
uniprot id: A0A0S2I0M3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1307839:L21SP5 RS02285
gene id: 1307839:L21SP5_RS02285
uniprot id: A0A0S2HVT8
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS13655
gene id: 1307839:L21SP5_RS13655
uniprot id: A0A0S2I2Y2
names: Similarity
messages: Belongs to the SusD family.

1307839:L21SP5 RS18800
gene id: 1307839:L21SP5_RS18800
uniprot id: A0A0S2I577
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1307839:L21SP5 RS04820
gene id: 1307839:L21SP5_RS04820
uniprot id: A0A0S2I582
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1307839:L21SP5 RS17260
gene id: 1307839:L21SP5_RS17260
uniprot id: A0A0S2I4J2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1307839:L21SP5 RS12940
gene id: 1307839:L21SP5_RS12940
uniprot id: A0A0S2I1U2
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS15575
gene id: 1307839:L21SP5_RS15575
uniprot id: A0A0S2I317
names: Similarity
messages: Belongs to the DNA photolyase family.

1307839:L21SP5 RS13430
gene id: 1307839:L21SP5_RS13430
uniprot id: A0A0S2I224
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

1307839:L21SP5 RS06605
gene id: 1307839:L21SP5_RS06605
uniprot id: A0A0S2HYA8
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS13040
gene id: 1307839:L21SP5_RS13040
uniprot id: A0A0S2I1Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1307839:L21SP5 RS06120
gene id: 1307839:L21SP5_RS06120
uniprot id: A0A0S2HY36
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1307839:L21SP5 RS12480
gene id: 1307839:L21SP5_RS12480
uniprot id: A0A0S2I1G9
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1307839:L21SP5 RS06945
gene id: 1307839:L21SP5_RS06945
uniprot id: A0A0S2HYZ4
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1307839:L21SP5 RS04045
gene id: 1307839:L21SP5_RS04045
uniprot id: A0A0S2HWR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS06300
gene id: 1307839:L21SP5_RS06300
uniprot id: A0A0S2HXT7
names: Similarity
messages: Belongs to the HypD family.

1307839:L21SP5 RS08175
gene id: 1307839:L21SP5_RS08175
uniprot id: A0A0S2HZD4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS11095
gene id: 1307839:L21SP5_RS11095
uniprot id: A0A0S2I0R7
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS12750
gene id: 1307839:L21SP5_RS12750
uniprot id: A0A0S2I1W8
names: Similarity
messages: Belongs to the pirin family.

1307839:L21SP5 RS08765
gene id: 1307839:L21SP5_RS08765
uniprot id: A0A0S2I0A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1307839:L21SP5 RS17010
gene id: 1307839:L21SP5_RS17010
uniprot id: A0A0S2I3P1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1307839:L21SP5 RS19050
gene id: 1307839:L21SP5_RS19050
uniprot id: A0A0S2I5A3
names: Subcellular Location Annotation
messages: Nucleus

1307839:L21SP5 RS14870
gene id: 1307839:L21SP5_RS14870
uniprot id: A0A0S2I313
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1307839:L21SP5 RS02995
gene id: 1307839:L21SP5_RS02995
uniprot id: A0A0S2HW41
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1307839:L21SP5 RS10050
gene id: 1307839:L21SP5_RS10050
uniprot id: A0A0S2I052
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1307839:L21SP5 RS07050
gene id: 1307839:L21SP5_RS07050
uniprot id: A0A0S2HYL9
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1307839:L21SP5 RS17425
gene id: 1307839:L21SP5_RS17425
uniprot id: A0A0S2I3V3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1307839:L21SP5 RS12675
gene id: 1307839:L21SP5_RS12675
uniprot id: A0A0S2I1G4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1307839:L21SP5 RS18215
gene id: 1307839:L21SP5_RS18215
uniprot id: A0A0S2I4M1
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS17890
gene id: 1307839:L21SP5_RS17890
uniprot id: A0A0S2I4T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS08770
gene id: 1307839:L21SP5_RS08770
uniprot id: A0A0S2HZI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1307839:L21SP5 RS13485
gene id: 1307839:L21SP5_RS13485
uniprot id: A0A0S2I1W5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1307839:L21SP5 RS16775
gene id: 1307839:L21SP5_RS16775
uniprot id: A0A0S2I468
names: Similarity
messages: Belongs to the peptidase C56 family.

1307839:L21SP5 RS14100
gene id: 1307839:L21SP5_RS14100
uniprot id: A0A0S2I2A4
names: Similarity
messages: Belongs to the pyruvate kinase family.

1307839:L21SP5 RS10245
gene id: 1307839:L21SP5_RS10245
uniprot id: A0A0S2I070
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS12945
gene id: 1307839:L21SP5_RS12945
uniprot id: A0A0S2I1U1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS12330
gene id: 1307839:L21SP5_RS12330
uniprot id: A0A0S2I1J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1307839:L21SP5 RS15080
gene id: 1307839:L21SP5_RS15080
uniprot id: A0A0S2I382
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1307839:L21SP5 RS14520
gene id: 1307839:L21SP5_RS14520
uniprot id: A0A0S2I2X4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1307839:L21SP5 RS19250
gene id: 1307839:L21SP5_RS19250
uniprot id: A0A0S2I4X4
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS10760
gene id: 1307839:L21SP5_RS10760
uniprot id: A0A0S2I1D5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1307839:L21SP5 RS19385
gene id: 1307839:L21SP5_RS19385
uniprot id: A0A0S2I5T7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1307839:L21SP5 RS08845
gene id: 1307839:L21SP5_RS08845
uniprot id: A0A0S2I0B5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1307839:L21SP5 RS10910
gene id: 1307839:L21SP5_RS10910
uniprot id: A0A0S2I0I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1307839:L21SP5 RS00005
gene id: 1307839:L21SP5_RS00005
uniprot id: A0A0S2HUD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1307839:L21SP5 RS15985
gene id: 1307839:L21SP5_RS15985
uniprot id: A0A0S2I3U1
names: Caution
names: Function
names: Similarity
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).

1307839:L21SP5 RS19060
gene id: 1307839:L21SP5_RS19060
uniprot id: A0A0S2I4Z9
names: Function
messages: Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase.

1307839:L21SP5 RS01730
gene id: 1307839:L21SP5_RS01730
uniprot id: A0A0S2HVI0
names: Similarity
messages: Belongs to the PspA/IM30 family.

1307839:L21SP5 RS12860
gene id: 1307839:L21SP5_RS12860
uniprot id: A0A0S2I2J2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1307839:L21SP5 RS07700
gene id: 1307839:L21SP5_RS07700
uniprot id: A0A0S2HYY9
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1307839:L21SP5 RS08980
gene id: 1307839:L21SP5_RS08980
uniprot id: A0A0S2HZI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: Membrane

1307839:L21SP5 RS12530
gene id: 1307839:L21SP5_RS12530
uniprot id: A0A0S2I1R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1307839:L21SP5 RS08210
gene id: 1307839:L21SP5_RS08210
uniprot id: A0A0S2HZM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1307839:L21SP5 RS06235
gene id: 1307839:L21SP5_RS06235
uniprot id: A0A0S2HYK4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS03890
gene id: 1307839:L21SP5_RS03890
uniprot id: A0A0S2HWM9
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1307839:L21SP5 RS02975
gene id: 1307839:L21SP5_RS02975
uniprot id: A0A0S2HW98
names: Subcellular Location Annotation
messages: Secreted

1307839:L21SP5 RS15015
gene id: 1307839:L21SP5_RS15015
uniprot id: A0A0S2I355
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1307839:L21SP5 RS07565
gene id: 1307839:L21SP5_RS07565
uniprot id: A0A0S2HYS2
names: Similarity
messages: Belongs to the universal stress protein A family.

1307839:L21SP5 RS10800
gene id: 1307839:L21SP5_RS10800
uniprot id: A0A0S2I0H8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1307839:L21SP5 RS13705
gene id: 1307839:L21SP5_RS13705
uniprot id: A0A0S2I238
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

1307839:L21SP5 RS05700
gene id: 1307839:L21SP5_RS05700
uniprot id: A0A0S2HXJ9
names: Function
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.

1307839:L21SP5 RS04900
gene id: 1307839:L21SP5_RS04900
uniprot id: A0A0S2HX87
names: Similarity
messages: Belongs to the peptidase S41A family.

1307839:L21SP5 RS15520
gene id: 1307839:L21SP5_RS15520
uniprot id: A0A0S2I381
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS05245
gene id: 1307839:L21SP5_RS05245
uniprot id: A0A0S2HXF5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS10550
gene id: 1307839:L21SP5_RS10550
uniprot id: A0A0S2I0A3
names: Similarity
messages: Belongs to the FemABX family.

1307839:L21SP5 RS07775
gene id: 1307839:L21SP5_RS07775
uniprot id: A0A0S2HYS6
names: Similarity
messages: Belongs to the nitroreductase family.

1307839:L21SP5 RS15290
gene id: 1307839:L21SP5_RS15290
uniprot id: A0A0S2I349
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1307839:L21SP5 RS06070
gene id: 1307839:L21SP5_RS06070
uniprot id: A0A0S2HXV0
names: Similarity
messages: Belongs to the UPF0047 family.

1307839:L21SP5 RS08400
gene id: 1307839:L21SP5_RS08400
uniprot id: A0A0S2HZC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS12555
gene id: 1307839:L21SP5_RS12555
uniprot id: A0A0S2I1I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1307839:L21SP5 RS08600
gene id: 1307839:L21SP5_RS08600
uniprot id: A0A0S2HZF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1307839:L21SP5 RS00200
gene id: 1307839:L21SP5_RS00200
uniprot id: A0A0S2HUH3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1307839:L21SP5 RS11320
gene id: 1307839:L21SP5_RS11320
uniprot id: A0A0S2I0W3
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS12365
gene id: 1307839:L21SP5_RS12365
uniprot id: A0A0S2I186
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1307839:L21SP5 RS15555
gene id: 1307839:L21SP5_RS15555
uniprot id: A0A0S2I3M2
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1307839:L21SP5 RS11120
gene id: 1307839:L21SP5_RS11120
uniprot id: A0A0S2I165
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1307839:L21SP5 RS04170
gene id: 1307839:L21SP5_RS04170
uniprot id: A0A0S2HWT0
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1307839:L21SP5 RS11255
gene id: 1307839:L21SP5_RS11255
uniprot id: A0A0S2I0U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS11635
gene id: 1307839:L21SP5_RS11635
uniprot id: A0A0S2I121
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS08160
gene id: 1307839:L21SP5_RS08160
uniprot id: A0A0S2HZ81
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1307839:L21SP5 RS09990
gene id: 1307839:L21SP5_RS09990
uniprot id: A0A0S2I073
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS14475
gene id: 1307839:L21SP5_RS14475
uniprot id: A0A0S2I2M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1307839:L21SP5 RS08940
gene id: 1307839:L21SP5_RS08940
uniprot id: A0A0S2HZF8
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1307839:L21SP5 RS12985
gene id: 1307839:L21SP5_RS12985
uniprot id: A0A0S2I1Q1
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1307839:L21SP5 RS19310
gene id: 1307839:L21SP5_RS19310
uniprot id: A0A0S2I5S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

1307839:L21SP5 RS14970
gene id: 1307839:L21SP5_RS14970
uniprot id: A0A0S2I304
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1307839:L21SP5 RS11600
gene id: 1307839:L21SP5_RS11600
uniprot id: A0A0S2I0V7
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS02655
gene id: 1307839:L21SP5_RS02655
uniprot id: A0A0S2HVW6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1307839:L21SP5 RS11805
gene id: 1307839:L21SP5_RS11805
uniprot id: A0A0S2HVM7
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

1307839:L21SP5 RS17595
gene id: 1307839:L21SP5_RS17595
uniprot id: A0A0S2I4Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1307839:L21SP5 RS11405
gene id: 1307839:L21SP5_RS11405
uniprot id: A0A0S2I0W6
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1307839:L21SP5 RS08070
gene id: 1307839:L21SP5_RS08070
uniprot id: A0A0S2HZ00
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1307839:L21SP5 RS12640
gene id: 1307839:L21SP5_RS12640
uniprot id: A0A0S2I1K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS13135
gene id: 1307839:L21SP5_RS13135
uniprot id: A0A0S2I1M0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1307839:L21SP5 RS14785
gene id: 1307839:L21SP5_RS14785
uniprot id: A0A0S2I2Y3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1307839:L21SP5 RS02835
gene id: 1307839:L21SP5_RS02835
uniprot id: A0A0S2HW50
names: Similarity
messages: Belongs to the FemABX family.

1307839:L21SP5 RS10625
gene id: 1307839:L21SP5_RS10625
uniprot id: A0A0S2I0H3
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

1307839:L21SP5 RS19375
gene id: 1307839:L21SP5_RS19375
uniprot id: A0A0S2I5I4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1307839:L21SP5 RS09020
gene id: 1307839:L21SP5_RS09020
uniprot id: A0A0S2HZH5
names: Similarity
messages: Belongs to the MEMO1 family.

1307839:L21SP5 RS18290
gene id: 1307839:L21SP5_RS18290
uniprot id: A0A0S2I4Z2
names: Similarity
messages: Belongs to the universal stress protein A family.

1307839:L21SP5 RS08595
gene id: 1307839:L21SP5_RS08595
uniprot id: A0A0S2HZ96
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1307839:L21SP5 RS04740
gene id: 1307839:L21SP5_RS04740
uniprot id: A0A0S2HX54
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS14990
gene id: 1307839:L21SP5_RS14990
uniprot id: A0A0S2I2K1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1307839:L21SP5 RS08750
gene id: 1307839:L21SP5_RS08750
uniprot id: A0A0S2HZ69
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS18700
gene id: 1307839:L21SP5_RS18700
uniprot id: A0A0S2I5G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1307839:L21SP5 RS04175
gene id: 1307839:L21SP5_RS04175
uniprot id: A0A0S2HWN9
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1307839:L21SP5 RS14325
gene id: 1307839:L21SP5_RS14325
uniprot id: A0A0S2I282
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1307839:L21SP5 RS07635
gene id: 1307839:L21SP5_RS07635
uniprot id: A0A0S2HYU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

1307839:L21SP5 RS02355
gene id: 1307839:L21SP5_RS02355
uniprot id: A0A0S2HVS2
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1307839:L21SP5 RS19025
gene id: 1307839:L21SP5_RS19025
uniprot id: A0A0S2I663
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1307839:L21SP5 RS17245
gene id: 1307839:L21SP5_RS17245
uniprot id: A0A0S2I3S2
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS00075
gene id: 1307839:L21SP5_RS00075
uniprot id: A0A0S2HUF4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1307839:L21SP5 RS11910
gene id: 1307839:L21SP5_RS11910
uniprot id: A0A0S2I147
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1307839:L21SP5 RS05240
gene id: 1307839:L21SP5_RS05240
uniprot id: A0A0S2HXF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1307839:L21SP5 RS01660
gene id: 1307839:L21SP5_RS01660
uniprot id: A0A0S2HVC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS16085
gene id: 1307839:L21SP5_RS16085
uniprot id: A0A0S2I3I5
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1307839:L21SP5 RS18710
gene id: 1307839:L21SP5_RS18710
uniprot id: A0A0S2I5A8
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1307839:L21SP5 RS04015
gene id: 1307839:L21SP5_RS04015
uniprot id: A0A0S2HWK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1307839:L21SP5 RS10975
gene id: 1307839:L21SP5_RS10975
uniprot id: A0A0S2I0I4
names: Similarity
messages: Belongs to the hemerythrin family.

1307839:L21SP5 RS01710
gene id: 1307839:L21SP5_RS01710
uniprot id: A0A0S2HVD4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS16465
gene id: 1307839:L21SP5_RS16465
uniprot id: A0A0S2I461
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1307839:L21SP5 RS04440
gene id: 1307839:L21SP5_RS04440
uniprot id: A0A0S2HWW7
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1307839:L21SP5 RS15320
gene id: 1307839:L21SP5_RS15320
uniprot id: A0A0S2I2S3
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1307839:L21SP5 RS04040
gene id: 1307839:L21SP5_RS04040
uniprot id: A0A0S2HXC4
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1307839:L21SP5 RS01915
gene id: 1307839:L21SP5_RS01915
uniprot id: A0A0S2HVI4
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1307839:L21SP5 RS02455
gene id: 1307839:L21SP5_RS02455
uniprot id: A0A0S2HVS3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1307839:L21SP5 RS15280
gene id: 1307839:L21SP5_RS15280
uniprot id: A0A0S2I368
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1307839:L21SP5 RS13255
gene id: 1307839:L21SP5_RS13255
uniprot id: A0A0S2I252
names: Similarity
messages: Belongs to the Fur family.

1307839:L21SP5 RS13005
gene id: 1307839:L21SP5_RS13005
uniprot id: A0A0S2I1V9
names: Similarity
messages: Belongs to the MEMO1 family.

1307839:L21SP5 RS04555
gene id: 1307839:L21SP5_RS04555
uniprot id: A0A0S2HX33
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1307839:L21SP5 RS08385
gene id: 1307839:L21SP5_RS08385
uniprot id: A0A0S2HZ64
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1307839:L21SP5 RS05720
gene id: 1307839:L21SP5_RS05720
uniprot id: A0A0S2HXN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1307839:L21SP5 RS09525
gene id: 1307839:L21SP5_RS09525
uniprot id: A0A0S2HZK7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1307839:L21SP5 RS15140
gene id: 1307839:L21SP5_RS15140
uniprot id: A0A0S2I371
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS10100
gene id: 1307839:L21SP5_RS10100
uniprot id: A0A0S2I0A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1307839:L21SP5 RS05775
gene id: 1307839:L21SP5_RS05775
uniprot id: A0A0S2HXS6
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1307839:L21SP5 RS15040
gene id: 1307839:L21SP5_RS15040
uniprot id: A0A0S2I2Z6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1307839:L21SP5 RS07605
gene id: 1307839:L21SP5_RS07605
uniprot id: A0A0S2HYZ0
names: Similarity
messages: Belongs to the DprA/Smf family.

1307839:L21SP5 RS05160
gene id: 1307839:L21SP5_RS05160
uniprot id: A0A0S2HXD7
names: Similarity
messages: Belongs to the peptidase C40 family.

1307839:L21SP5 RS05365
gene id: 1307839:L21SP5_RS05365
uniprot id: A0A0S2HXK1
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS16555
gene id: 1307839:L21SP5_RS16555
uniprot id: A0A0S2I3R1
names: Similarity
messages: Belongs to the DDAH family.

1307839:L21SP5 RS14565
gene id: 1307839:L21SP5_RS14565
uniprot id: A0A0S2I2C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1307839:L21SP5 RS05210
gene id: 1307839:L21SP5_RS05210
uniprot id: A0A0S2HXE3
names: Similarity
messages: Belongs to the RutC family.

1307839:L21SP5 RS14915
gene id: 1307839:L21SP5_RS14915
uniprot id: A0A0S2I2P0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1307839:L21SP5 RS04670
gene id: 1307839:L21SP5_RS04670
uniprot id: A0A0S2HWZ2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated Cas9 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.
messages: Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.
messages: Monomer. Binds crRNA and tracrRNA.

1307839:L21SP5 RS05265
gene id: 1307839:L21SP5_RS05265
uniprot id: A0A0S2HXH7
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS16205
gene id: 1307839:L21SP5_RS16205
uniprot id: A0A0S2I3A0
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS00145
gene id: 1307839:L21SP5_RS00145
uniprot id: A0A0S2HUJ0
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS17210
gene id: 1307839:L21SP5_RS17210
uniprot id: A0A0S2I446
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1307839:L21SP5 RS02830
gene id: 1307839:L21SP5_RS02830
uniprot id: A0A0S2HW69
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1307839:L21SP5 RS14415
gene id: 1307839:L21SP5_RS14415
uniprot id: A0A0S2I2Y6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1307839:L21SP5 RS17470
gene id: 1307839:L21SP5_RS17470
uniprot id: A0A0S2I4A0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS16480
gene id: 1307839:L21SP5_RS16480
uniprot id: A0A0S2I3S8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1307839:L21SP5 RS03635
gene id: 1307839:L21SP5_RS03635
uniprot id: A0A0S2HWE5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1307839:L21SP5 RS04260
gene id: 1307839:L21SP5_RS04260
uniprot id: A0A0S2HWR1
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1307839:L21SP5 RS13985
gene id: 1307839:L21SP5_RS13985
uniprot id: A0A0S2I2H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS06830
gene id: 1307839:L21SP5_RS06830
uniprot id: A0A0S2HYF2
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

1307839:L21SP5 RS03900
gene id: 1307839:L21SP5_RS03900
uniprot id: A0A0S2HWP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1307839:L21SP5 RS13660
gene id: 1307839:L21SP5_RS13660
uniprot id: A0A0S2I2D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1307839:L21SP5 RS06410
gene id: 1307839:L21SP5_RS06410
uniprot id: A0A0S2HXY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1307839:L21SP5 RS09955
gene id: 1307839:L21SP5_RS09955
uniprot id: A0A0S2I049
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1307839:L21SP5 RS13310
gene id: 1307839:L21SP5_RS13310
uniprot id: A0A0S2I1W3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS09415
gene id: 1307839:L21SP5_RS09415
uniprot id: A0A0S2HZL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1307839:L21SP5 RS08050
gene id: 1307839:L21SP5_RS08050
uniprot id: A0A0S2HZJ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1307839:L21SP5 RS05145
gene id: 1307839:L21SP5_RS05145
uniprot id: A0A0S2HXA2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1307839:L21SP5 RS12950
gene id: 1307839:L21SP5_RS12950
uniprot id: A0A0S2I1Z3
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS13000
gene id: 1307839:L21SP5_RS13000
uniprot id: A0A0S2I1P6
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1307839:L21SP5 RS10905
gene id: 1307839:L21SP5_RS10905
uniprot id: A0A0S2I0B4
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1307839:L21SP5 RS15030
gene id: 1307839:L21SP5_RS15030
uniprot id: A0A0S2I336
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1307839:L21SP5 RS01790
gene id: 1307839:L21SP5_RS01790
uniprot id: A0A0S2HVF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1307839:L21SP5 RS15955
gene id: 1307839:L21SP5_RS15955
uniprot id: A0A0S2I3U8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1307839:L21SP5 RS06050
gene id: 1307839:L21SP5_RS06050
uniprot id: A0A0S2HY25
names: Similarity
messages: Belongs to the peptidase A8 family.

1307839:L21SP5 RS00155
gene id: 1307839:L21SP5_RS00155
uniprot id: A0A0S2HUI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1307839:L21SP5 RS07465
gene id: 1307839:L21SP5_RS07465
uniprot id: A0A0S2HYK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1307839:L21SP5 RS08970
gene id: 1307839:L21SP5_RS08970
uniprot id: A0A0S2HZY0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1307839:L21SP5 RS13320
gene id: 1307839:L21SP5_RS13320
uniprot id: A0A0S2I1P5
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS06055
gene id: 1307839:L21SP5_RS06055
uniprot id: A0A0S2HXT2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1307839:L21SP5 RS05045
gene id: 1307839:L21SP5_RS05045
uniprot id: A0A0S2HXA7
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

1307839:L21SP5 RS16060
gene id: 1307839:L21SP5_RS16060
uniprot id: A0A0S2I3T4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1307839:L21SP5 RS08015
gene id: 1307839:L21SP5_RS08015
uniprot id: A0A0S2HZA5
names: Similarity
messages: Belongs to the UPF0251 family.

1307839:L21SP5 RS11470
gene id: 1307839:L21SP5_RS11470
uniprot id: A0A0S2I144
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1307839:L21SP5 RS15130
gene id: 1307839:L21SP5_RS15130
uniprot id: A0A0S2I3B4
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1307839:L21SP5 RS15105
gene id: 1307839:L21SP5_RS15105
uniprot id: A0A0S2I353
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1307839:L21SP5 RS17190
gene id: 1307839:L21SP5_RS17190
uniprot id: A0A0S2I4K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1307839:L21SP5 RS19355
gene id: 1307839:L21SP5_RS19355
uniprot id: A0A0S2I5M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1307839:L21SP5 RS06305
gene id: 1307839:L21SP5_RS06305
uniprot id: A0A0S2HXZ1
names: Similarity
messages: Belongs to the HypE family.

1307839:L21SP5 RS08760
gene id: 1307839:L21SP5_RS08760
uniprot id: A0A0S2HZI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1307839:L21SP5 RS05500
gene id: 1307839:L21SP5_RS05500
uniprot id: A0A0S2HXF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1307839:L21SP5 RS18090
gene id: 1307839:L21SP5_RS18090
uniprot id: A0A0S2I508
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1307839:L21SP5 RS14105
gene id: 1307839:L21SP5_RS14105
uniprot id: A0A0S2I2L5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS05495
gene id: 1307839:L21SP5_RS05495
uniprot id: A0A0S2HXG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1307839:L21SP5 RS10145
gene id: 1307839:L21SP5_RS10145
uniprot id: A0A0S2I099
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1307839:L21SP5 RS12345
gene id: 1307839:L21SP5_RS12345
uniprot id: A0A0S2I1S0
names: Similarity
messages: Belongs to the ArsC family.

1307839:L21SP5 RS15035
gene id: 1307839:L21SP5_RS15035
uniprot id: A0A0S2I2X1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1307839:L21SP5 RS14730
gene id: 1307839:L21SP5_RS14730
uniprot id: A0A0S2I2F5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1307839:L21SP5 RS11870
gene id: 1307839:L21SP5_RS11870
uniprot id: A0A0S2I0Z5
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS12400
gene id: 1307839:L21SP5_RS12400
uniprot id: A0A0S2I1F0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1307839:L21SP5 RS05670
gene id: 1307839:L21SP5_RS05670
uniprot id: A0A0S2HXM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1307839:L21SP5 RS09890
gene id: 1307839:L21SP5_RS09890
uniprot id: A0A0S2HZV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1307839:L21SP5 RS00090
gene id: 1307839:L21SP5_RS00090
uniprot id: A0A0S2HUQ3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS02915
gene id: 1307839:L21SP5_RS02915
uniprot id: A0A0S2HW31
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS02730
gene id: 1307839:L21SP5_RS02730
uniprot id: A0A0S2HVY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1307839:L21SP5 RS19140
gene id: 1307839:L21SP5_RS19140
uniprot id: A0A0S2I511
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1307839:L21SP5 RS14375
gene id: 1307839:L21SP5_RS14375
uniprot id: A0A0S2I2T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1307839:L21SP5 RS08575
gene id: 1307839:L21SP5_RS08575
uniprot id: A0A0S2HZE6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1307839:L21SP5 RS09175
gene id: 1307839:L21SP5_RS09175
uniprot id: A0A0S2HZQ8
names: Similarity
messages: Belongs to the asparaginase 1 family.

1307839:L21SP5 RS10945
gene id: 1307839:L21SP5_RS10945
uniprot id: A0A0S2I0U6
names: Similarity
messages: Belongs to the UPF0246 family.

1307839:L21SP5 RS12150
gene id: 1307839:L21SP5_RS12150
uniprot id: A0A0S2I1F9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1307839:L21SP5 RS18275
gene id: 1307839:L21SP5_RS18275
uniprot id: A0A0S2I4I5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1307839:L21SP5 RS09870
gene id: 1307839:L21SP5_RS09870
uniprot id: A0A0S2HZZ8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1307839:L21SP5 RS16355
gene id: 1307839:L21SP5_RS16355
uniprot id: A0A0S2I3Y0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1307839:L21SP5 RS19325
gene id: 1307839:L21SP5_RS19325
uniprot id: A0A0S2I525
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1307839:L21SP5 RS03795
gene id: 1307839:L21SP5_RS03795
uniprot id: A0A0S2HWG7
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1307839:L21SP5 RS09325
gene id: 1307839:L21SP5_RS09325
uniprot id: A0A0S2I2T4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1307839:L21SP5 RS11325
gene id: 1307839:L21SP5_RS11325
uniprot id: A0A0S2I114
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS08060
gene id: 1307839:L21SP5_RS08060
uniprot id: A0A0S2HZ21
names: Similarity
messages: Belongs to the UPF0102 family.

1307839:L21SP5 RS08790
gene id: 1307839:L21SP5_RS08790
uniprot id: A0A0S2HZI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: Membrane

1307839:L21SP5 RS13695
gene id: 1307839:L21SP5_RS13695
uniprot id: A0A0S2I2A7
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

1307839:L21SP5 RS14300
gene id: 1307839:L21SP5_RS14300
uniprot id: A0A0S2I2H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBS4 family.
messages: Membrane
messages: centrosome
messages: cilium membrane

1307839:L21SP5 RS14435
gene id: 1307839:L21SP5_RS14435
uniprot id: A0A0S2I2F2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS17375
gene id: 1307839:L21SP5_RS17375
uniprot id: A0A0S2I492
names: Similarity
messages: Belongs to the histone deacetylase family.

1307839:L21SP5 RS11170
gene id: 1307839:L21SP5_RS11170
uniprot id: A0A0S2I0N5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1307839:L21SP5 RS03660
gene id: 1307839:L21SP5_RS03660
uniprot id: A0A0S2HWJ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS03535
gene id: 1307839:L21SP5_RS03535
uniprot id: A0A0S2HWP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1307839:L21SP5 RS00330
gene id: 1307839:L21SP5_RS00330
uniprot id: A0A0S2HUU9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS12465
gene id: 1307839:L21SP5_RS12465
uniprot id: A0A0S2I1K8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS15995
gene id: 1307839:L21SP5_RS15995
uniprot id: A0A0S2I3X4
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1307839:L21SP5 RS15245
gene id: 1307839:L21SP5_RS15245
uniprot id: A0A0S2I2Q7
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1307839:L21SP5 RS13245
gene id: 1307839:L21SP5_RS13245
uniprot id: A0A0S2I1S8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1307839:L21SP5 RS16105
gene id: 1307839:L21SP5_RS16105
uniprot id: A0A0S2I3N8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1307839:L21SP5 RS01630
gene id: 1307839:L21SP5_RS01630
uniprot id: A0A0S2HVB8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1307839:L21SP5 RS14905
gene id: 1307839:L21SP5_RS14905
uniprot id: A0A0S2I323
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1307839:L21SP5 RS12765
gene id: 1307839:L21SP5_RS12765
uniprot id: A0A0S2I1H9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1307839:L21SP5 RS02075
gene id: 1307839:L21SP5_RS02075
uniprot id: A0A0S2HVJ6
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1307839:L21SP5 RS02275
gene id: 1307839:L21SP5_RS02275
uniprot id: A0A0S2HVW9
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1307839:L21SP5 RS05455
gene id: 1307839:L21SP5_RS05455
uniprot id: A0A0S2HXH8
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1307839:L21SP5 RS08920
gene id: 1307839:L21SP5_RS08920
uniprot id: A0A0S2HZK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1307839:L21SP5 RS08635
gene id: 1307839:L21SP5_RS08635
uniprot id: A0A0S2HZG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1307839:L21SP5 RS12875
gene id: 1307839:L21SP5_RS12875
uniprot id: A0A0S2I1X7
names: Similarity
messages: Belongs to the DEAD box helicase family.

1307839:L21SP5 RS07575
gene id: 1307839:L21SP5_RS07575
uniprot id: A0A0S2HYU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1307839:L21SP5 RS19330
gene id: 1307839:L21SP5_RS19330
uniprot id: A0A0S2I4Y8
names: Similarity
messages: Belongs to the Fur family.

1307839:L21SP5 RS07685
gene id: 1307839:L21SP5_RS07685
uniprot id: A0A0S2HZ02
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1307839:L21SP5 RS12805
gene id: 1307839:L21SP5_RS12805
uniprot id: A0A0S2I1M3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

1307839:L21SP5 RS10715
gene id: 1307839:L21SP5_RS10715
uniprot id: A0A0S2I0C5
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS12660
gene id: 1307839:L21SP5_RS12660
uniprot id: A0A0S2I1Z2
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1307839:L21SP5 RS04625
gene id: 1307839:L21SP5_RS04625
uniprot id: A0A0S2HX40
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1307839:L21SP5 RS10025
gene id: 1307839:L21SP5_RS10025
uniprot id: A0A0S2I068
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1307839:L21SP5 RS05510
gene id: 1307839:L21SP5_RS05510
uniprot id: A0A0S2HXH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1307839:L21SP5 RS17555
gene id: 1307839:L21SP5_RS17555
uniprot id: A0A0S2I458
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1307839:L21SP5 RS02260
gene id: 1307839:L21SP5_RS02260
uniprot id: A0A0S2HVP7
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1307839:L21SP5 RS19380
gene id: 1307839:L21SP5_RS19380
uniprot id: A0A0S2I556
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1307839:L21SP5 RS09075
gene id: 1307839:L21SP5_RS09075
uniprot id: A0A0S2HZP0
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS08430
gene id: 1307839:L21SP5_RS08430
uniprot id: A0A0S2HZ71
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS11505
gene id: 1307839:L21SP5_RS11505
uniprot id: A0A0S2I1E7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1307839:L21SP5 RS08620
gene id: 1307839:L21SP5_RS08620
uniprot id: A0A0S2HZ94
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS03075
gene id: 1307839:L21SP5_RS03075
uniprot id: A0A0S2HWB1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1307839:L21SP5 RS12105
gene id: 1307839:L21SP5_RS12105
uniprot id: A0A0S2I1N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1307839:L21SP5 RS10475
gene id: 1307839:L21SP5_RS10475
uniprot id: A0A0S2I0C3
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS13060
gene id: 1307839:L21SP5_RS13060
uniprot id: A0A0S2I261
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1307839:L21SP5 RS15240
gene id: 1307839:L21SP5_RS15240
uniprot id: A0A0S2I387
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1307839:L21SP5 RS18085
gene id: 1307839:L21SP5_RS18085
uniprot id: A0A0S2I5N7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1307839:L21SP5 RS01815
gene id: 1307839:L21SP5_RS01815
uniprot id: A0A0S2HVG5
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1307839:L21SP5 RS10695
gene id: 1307839:L21SP5_RS10695
uniprot id: A0A0S2I0D7
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1307839:L21SP5 RS08580
gene id: 1307839:L21SP5_RS08580
uniprot id: A0A0S2HZA2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1307839:L21SP5 RS10955
gene id: 1307839:L21SP5_RS10955
uniprot id: A0A0S2I0L6
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

1307839:L21SP5 RS13870
gene id: 1307839:L21SP5_RS13870
uniprot id: A0A0S2I2H2
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1307839:L21SP5 RS13065
gene id: 1307839:L21SP5_RS13065
uniprot id: A0A0S2I1S1
names: Similarity
messages: Belongs to the MreC family.

1307839:L21SP5 RS13675
gene id: 1307839:L21SP5_RS13675
uniprot id: A0A0S2I2B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1307839:L21SP5 RS03780
gene id: 1307839:L21SP5_RS03780
uniprot id: A0A0S2HWJ8
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS04295
gene id: 1307839:L21SP5_RS04295
uniprot id: A0A0S2HWY0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1307839:L21SP5 RS08455
gene id: 1307839:L21SP5_RS08455
uniprot id: A0A0S2HZD7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1307839:L21SP5 RS01635
gene id: 1307839:L21SP5_RS01635
uniprot id: A0A0S2HV97
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1307839:L21SP5 RS10355
gene id: 1307839:L21SP5_RS10355
uniprot id: A0A0S2I0D2
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1307839:L21SP5 RS10305
gene id: 1307839:L21SP5_RS10305
uniprot id: A0A0S2I0C7
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS05065
gene id: 1307839:L21SP5_RS05065
uniprot id: A0A0S2HX89
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1307839:L21SP5 RS09430
gene id: 1307839:L21SP5_RS09430
uniprot id: A0A0S2HZU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1307839:L21SP5 RS09860
gene id: 1307839:L21SP5_RS09860
uniprot id: A0A0S2I051
names: Similarity
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

1307839:L21SP5 RS17545
gene id: 1307839:L21SP5_RS17545
uniprot id: A0A0S2I4B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1307839:L21SP5 RS05360
gene id: 1307839:L21SP5_RS05360
uniprot id: A0A0S2HXN8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS13595
gene id: 1307839:L21SP5_RS13595
uniprot id: A0A0S2I2B4
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS00880
gene id: 1307839:L21SP5_RS00880
uniprot id: A0A0S2I2T4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1307839:L21SP5 RS04945
gene id: 1307839:L21SP5_RS04945
uniprot id: A0A0S2HX44
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1307839:L21SP5 RS14490
gene id: 1307839:L21SP5_RS14490
uniprot id: A0A0S2I2Q4
names: Similarity
messages: Belongs to the HSP15 family.

1307839:L21SP5 RS14455
gene id: 1307839:L21SP5_RS14455
uniprot id: A0A0S2I2V3
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1307839:L21SP5 RS06865
gene id: 1307839:L21SP5_RS06865
uniprot id: A0A0S2HYB9
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS00080
gene id: 1307839:L21SP5_RS00080
uniprot id: A0A0S2HUH1
names: Similarity
messages: Belongs to the FemABX family.

1307839:L21SP5 RS07980
gene id: 1307839:L21SP5_RS07980
uniprot id: A0A0S2HZ03
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1307839:L21SP5 RS03180
gene id: 1307839:L21SP5_RS03180
uniprot id: A0A0S2HWK3
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1307839:L21SP5 RS11020
gene id: 1307839:L21SP5_RS11020
uniprot id: A0A0S2I0Q6
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1307839:L21SP5 RS11105
gene id: 1307839:L21SP5_RS11105
uniprot id: A0A0S2I0W9
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS14280
gene id: 1307839:L21SP5_RS14280
uniprot id: A0A0S2I2S5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1307839:L21SP5 RS07035
gene id: 1307839:L21SP5_RS07035
uniprot id: A0A0S2HYC1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1307839:L21SP5 RS13225
gene id: 1307839:L21SP5_RS13225
uniprot id: A0A0S2I292
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1307839:L21SP5 RS06855
gene id: 1307839:L21SP5_RS06855
uniprot id: A0A0S2HY44
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS13300
gene id: 1307839:L21SP5_RS13300
uniprot id: A0A0S2I235
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS02495
gene id: 1307839:L21SP5_RS02495
uniprot id: A0A0S2HVT3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1307839:L21SP5 RS08800
gene id: 1307839:L21SP5_RS08800
uniprot id: A0A0S2HZ91
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS13185
gene id: 1307839:L21SP5_RS13185
uniprot id: A0A0S2I1Y6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS16190
gene id: 1307839:L21SP5_RS16190
uniprot id: A0A0S2I3Z4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1307839:L21SP5 RS11710
gene id: 1307839:L21SP5_RS11710
uniprot id: A0A0S2I141
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1307839:L21SP5 RS12225
gene id: 1307839:L21SP5_RS12225
uniprot id: A0A0S2I1D1
names: Similarity
messages: Belongs to the thioredoxin family.

1307839:L21SP5 RS05825
gene id: 1307839:L21SP5_RS05825
uniprot id: A0A0S2HYD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XseA family.
messages: Cytoplasm

1307839:L21SP5 RS14355
gene id: 1307839:L21SP5_RS14355
uniprot id: A0A0S2I2D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1307839:L21SP5 RS09865
gene id: 1307839:L21SP5_RS09865
uniprot id: A0A0S2I038
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1307839:L21SP5 RS18510
gene id: 1307839:L21SP5_RS18510
uniprot id: A0A0S2I537
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1307839:L21SP5 RS05940
gene id: 1307839:L21SP5_RS05940
uniprot id: A0A0S2HXN7
names: Similarity
messages: Belongs to the FBPase class 3 family.

1307839:L21SP5 RS08230
gene id: 1307839:L21SP5_RS08230
uniprot id: A0A0S2HZ42
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1307839:L21SP5 RS10325
gene id: 1307839:L21SP5_RS10325
uniprot id: A0A0S2I084
names: Similarity
messages: Belongs to the peptidase C1 family.

1307839:L21SP5 RS14765
gene id: 1307839:L21SP5_RS14765
uniprot id: A0A0S2I3R0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

1307839:L21SP5 RS03005
gene id: 1307839:L21SP5_RS03005
uniprot id: A0A0S2HW84
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1307839:L21SP5 RS11345
gene id: 1307839:L21SP5_RS11345
uniprot id: A0A0S2I0X8
names: Similarity
messages: Belongs to the universal stress protein A family.

1307839:L21SP5 RS03725
gene id: 1307839:L21SP5_RS03725
uniprot id: A0A0S2HWE7
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS14450
gene id: 1307839:L21SP5_RS14450
uniprot id: A0A0S2I3B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1307839:L21SP5 RS07060
gene id: 1307839:L21SP5_RS07060
uniprot id: A0A0S2HYJ0
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1307839:L21SP5 RS14795
gene id: 1307839:L21SP5_RS14795
uniprot id: A0A0S2I2T4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1307839:L21SP5 RS05395
gene id: 1307839:L21SP5_RS05395
uniprot id: A0A0S2HY74
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS10210
gene id: 1307839:L21SP5_RS10210
uniprot id: A0A0S2I019
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS00210
gene id: 1307839:L21SP5_RS00210
uniprot id: A0A0S2HUJ1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1307839:L21SP5 RS07135
gene id: 1307839:L21SP5_RS07135
uniprot id: A0A0S2HYK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1307839:L21SP5 RS02670
gene id: 1307839:L21SP5_RS02670
uniprot id: A0A0S2HVY3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1307839:L21SP5 RS03485
gene id: 1307839:L21SP5_RS03485
uniprot id: A0A0S2HWC3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1307839:L21SP5 RS17420
gene id: 1307839:L21SP5_RS17420
uniprot id: A0A0S2I4H2
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS14985
gene id: 1307839:L21SP5_RS14985
uniprot id: A0A0S2I350
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1307839:L21SP5 RS05515
gene id: 1307839:L21SP5_RS05515
uniprot id: A0A0S2HXR3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1307839:L21SP5 RS13710
gene id: 1307839:L21SP5_RS13710
uniprot id: A0A0S2I2E3
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

1307839:L21SP5 RS18460
gene id: 1307839:L21SP5_RS18460
uniprot id: A0A0S2I4K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1307839:L21SP5 RS06820
gene id: 1307839:L21SP5_RS06820
uniprot id: A0A0S2HYI1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1307839:L21SP5 RS13795
gene id: 1307839:L21SP5_RS13795
uniprot id: A0A0S2I2F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1307839:L21SP5 RS17550
gene id: 1307839:L21SP5_RS17550
uniprot id: A0A0S2I4J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1307839:L21SP5 RS05750
gene id: 1307839:L21SP5_RS05750
uniprot id: A0A0S2HXP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1307839:L21SP5 RS14805
gene id: 1307839:L21SP5_RS14805
uniprot id: A0A0S2I2G9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1307839:L21SP5 RS09800
gene id: 1307839:L21SP5_RS09800
uniprot id: A0A0S2I022
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1307839:L21SP5 RS02900
gene id: 1307839:L21SP5_RS02900
uniprot id: A0A0S2HW87
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS06135
gene id: 1307839:L21SP5_RS06135
uniprot id: A0A0S2HXQ8
names: Similarity
messages: Belongs to the aspartokinase family.

1307839:L21SP5 RS19125
gene id: 1307839:L21SP5_RS19125
uniprot id: A0A0S2I571
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS12925
gene id: 1307839:L21SP5_RS12925
uniprot id: A0A0S2I1U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1307839:L21SP5 RS11410
gene id: 1307839:L21SP5_RS11410
uniprot id: A0A0S2I115
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1307839:L21SP5 RS15060
gene id: 1307839:L21SP5_RS15060
uniprot id: A0A0S2I2W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1307839:L21SP5 RS15150
gene id: 1307839:L21SP5_RS15150
uniprot id: A0A0S2I2T5
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1307839:L21SP5 RS04950
gene id: 1307839:L21SP5_RS04950
uniprot id: A0A0S2HXB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1307839:L21SP5 RS13070
gene id: 1307839:L21SP5_RS13070
uniprot id: A0A0S2I227
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1307839:L21SP5 RS18730
gene id: 1307839:L21SP5_RS18730
uniprot id: A0A0S2I500
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1307839:L21SP5 RS14340
gene id: 1307839:L21SP5_RS14340
uniprot id: A0A0S2I2F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1307839:L21SP5 RS14090
gene id: 1307839:L21SP5_RS14090
uniprot id: A0A0S2I2H7
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1307839:L21SP5 RS08510
gene id: 1307839:L21SP5_RS08510
uniprot id: A0A0S2HZ14
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1307839:L21SP5 RS00150
gene id: 1307839:L21SP5_RS00150
uniprot id: A0A0S2HUH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS15960
gene id: 1307839:L21SP5_RS15960
uniprot id: A0A0S2I3C8
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1307839:L21SP5 RS01445
gene id: 1307839:L21SP5_RS01445
uniprot id: A0A0S2HVA4
names: Similarity
messages: Belongs to the SUI1 family.

1307839:L21SP5 RS12895
gene id: 1307839:L21SP5_RS12895
uniprot id: A0A0S2I1J2
names: Subcellular Location Annotation
messages: Mitochondrion

1307839:L21SP5 RS05635
gene id: 1307839:L21SP5_RS05635
uniprot id: A0A0S2HXU0
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1307839:L21SP5 RS15075
gene id: 1307839:L21SP5_RS15075
uniprot id: A0A0S2I2R9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1307839:L21SP5 RS06275
gene id: 1307839:L21SP5_RS06275
uniprot id: A0A0S2HY49
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1307839:L21SP5 RS01775
gene id: 1307839:L21SP5_RS01775
uniprot id: A0A0S2HVC4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1307839:L21SP5 RS19305
gene id: 1307839:L21SP5_RS19305
uniprot id: A0A0S2I5Q8
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1307839:L21SP5 RS02590
gene id: 1307839:L21SP5_RS02590
uniprot id: A0A0S2HVW0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1307839:L21SP5 RS08425
gene id: 1307839:L21SP5_RS08425
uniprot id: A0A0S2HZ36
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1307839:L21SP5 RS17045
gene id: 1307839:L21SP5_RS17045
uniprot id: A0A0S2I406
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase 20 family.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the trehalose phosphatase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 20 family.

1307839:L21SP5 RS10095
gene id: 1307839:L21SP5_RS10095
uniprot id: A0A0S2I0Z9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1307839:L21SP5 RS12015
gene id: 1307839:L21SP5_RS12015
uniprot id: A0A0S2I111
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1307839:L21SP5 RS15115
gene id: 1307839:L21SP5_RS15115
uniprot id: A0A0S2I311
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1307839:L21SP5 RS09510
gene id: 1307839:L21SP5_RS09510
uniprot id: A0A0S2HZX3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS14755
gene id: 1307839:L21SP5_RS14755
uniprot id: A0A0S2I326
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

1307839:L21SP5 RS07780
gene id: 1307839:L21SP5_RS07780
uniprot id: A0A0S2HYX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1307839:L21SP5 RS10650
gene id: 1307839:L21SP5_RS10650
uniprot id: A0A0S2I0X6
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS07570
gene id: 1307839:L21SP5_RS07570
uniprot id: A0A0S2HZA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1307839:L21SP5 RS06860
gene id: 1307839:L21SP5_RS06860
uniprot id: A0A0S2HY99
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS14235
gene id: 1307839:L21SP5_RS14235
uniprot id: A0A0S2I2M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1307839:L21SP5 RS05090
gene id: 1307839:L21SP5_RS05090
uniprot id: A0A0S2HXB8
names: Similarity
messages: Belongs to the beta-eliminating lyase family.

1307839:L21SP5 RS00015
gene id: 1307839:L21SP5_RS00015
uniprot id: A0A0S2HUL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1307839:L21SP5 RS12205
gene id: 1307839:L21SP5_RS12205
uniprot id: A0A0S2I153
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1307839:L21SP5 RS14535
gene id: 1307839:L21SP5_RS14535
uniprot id: A0A0S2I2X0
names: Similarity
messages: Belongs to the Skp family.

1307839:L21SP5 RS13395
gene id: 1307839:L21SP5_RS13395
uniprot id: A0A0S2I286
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

1307839:L21SP5 RS12430
gene id: 1307839:L21SP5_RS12430
uniprot id: A0A0S2I1H6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1307839:L21SP5 RS18965
gene id: 1307839:L21SP5_RS18965
uniprot id: A0A0S2I543
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS00275
gene id: 1307839:L21SP5_RS00275
uniprot id: A0A0S2HUT1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1307839:L21SP5 RS09290
gene id: 1307839:L21SP5_RS09290
uniprot id: A0A0S2HZN3
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

1307839:L21SP5 RS04585
gene id: 1307839:L21SP5_RS04585
uniprot id: A0A0S2HX26
names: Similarity
messages: Belongs to the peptidase M16 family.

1307839:L21SP5 RS06295
gene id: 1307839:L21SP5_RS06295
uniprot id: A0A0S2HY45
names: Similarity
messages: Belongs to the HupF/HypC family.

1307839:L21SP5 RS08330
gene id: 1307839:L21SP5_RS08330
uniprot id: A0A0S2HZ72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1307839:L21SP5 RS04275
gene id: 1307839:L21SP5_RS04275
uniprot id: A0A0S2HXK2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1307839:L21SP5 RS03605
gene id: 1307839:L21SP5_RS03605
uniprot id: A0A0S2HWK9
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1307839:L21SP5 RS07505
gene id: 1307839:L21SP5_RS07505
uniprot id: A0A0S2HYL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1307839:L21SP5 RS10390
gene id: 1307839:L21SP5_RS10390
uniprot id: A0A0S2I056
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1307839:L21SP5 RS18785
gene id: 1307839:L21SP5_RS18785
uniprot id: A0A0S2I5H7
names: Cofactor
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.

1307839:L21SP5 RS07595
gene id: 1307839:L21SP5_RS07595
uniprot id: A0A0S2HYQ3
names: Similarity
messages: Belongs to the asparaginase 1 family.

1307839:L21SP5 RS14980
gene id: 1307839:L21SP5_RS14980
uniprot id: A0A0S2I2U3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1307839:L21SP5 RS17615
gene id: 1307839:L21SP5_RS17615
uniprot id: A0A0S2I4B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1307839:L21SP5 RS11035
gene id: 1307839:L21SP5_RS11035
uniprot id: A0A0S2I0M7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1307839:L21SP5 RS14465
gene id: 1307839:L21SP5_RS14465
uniprot id: A0A0S2I2S0
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1307839:L21SP5 RS05570
gene id: 1307839:L21SP5_RS05570
uniprot id: A0A0S2HXG3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1307839:L21SP5 RS13465
gene id: 1307839:L21SP5_RS13465
uniprot id: A0A0S2I2D0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS18835
gene id: 1307839:L21SP5_RS18835
uniprot id: A0A0S2I5I5
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

1307839:L21SP5 RS09895
gene id: 1307839:L21SP5_RS09895
uniprot id: A0A0S2I026
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1307839:L21SP5 RS11040
gene id: 1307839:L21SP5_RS11040
uniprot id: A0A0S2I149
names: Similarity
messages: Belongs to the SufE family.

1307839:L21SP5 RS08150
gene id: 1307839:L21SP5_RS08150
uniprot id: A0A0S2HZ26
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1307839:L21SP5 RS13715
gene id: 1307839:L21SP5_RS13715
uniprot id: A0A0S2I1V6
names: Similarity
messages: Belongs to the V-ATPase D subunit family.

1307839:L21SP5 RS05270
gene id: 1307839:L21SP5_RS05270
uniprot id: A0A0S2HXC8
names: Similarity
messages: Belongs to the arginine deiminase family.

1307839:L21SP5 RS05900
gene id: 1307839:L21SP5_RS05900
uniprot id: A0A0S2HXV5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS18210
gene id: 1307839:L21SP5_RS18210
uniprot id: A0A0S2I521
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS19195
gene id: 1307839:L21SP5_RS19195
uniprot id: A0A0S2I5E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1307839:L21SP5 RS09465
gene id: 1307839:L21SP5_RS09465
uniprot id: A0A0S2HZW6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1307839:L21SP5 RS13155
gene id: 1307839:L21SP5_RS13155
uniprot id: A0A0S2I236
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1307839:L21SP5 RS08360
gene id: 1307839:L21SP5_RS08360
uniprot id: A0A0S2HZ61
names: Subcellular Location Annotation
messages: Secreted

1307839:L21SP5 RS11640
gene id: 1307839:L21SP5_RS11640
uniprot id: A0A0S2I113
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1307839:L21SP5 RS07140
gene id: 1307839:L21SP5_RS07140
uniprot id: A0A0S2HYK6
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS04335
gene id: 1307839:L21SP5_RS04335
uniprot id: A0A0S2HX32
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1307839:L21SP5 RS15570
gene id: 1307839:L21SP5_RS15570
uniprot id: A0A0S2I2X9
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

1307839:L21SP5 RS08755
gene id: 1307839:L21SP5_RS08755
uniprot id: A0A0S2HZD0
names: Similarity
messages: Belongs to the glutamine synthetase family.

1307839:L21SP5 RS16610
gene id: 1307839:L21SP5_RS16610
uniprot id: A0A0S2I441
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

1307839:L21SP5 RS17370
gene id: 1307839:L21SP5_RS17370
uniprot id: A0A0S2I4N0
names: Similarity
messages: Belongs to the UPF0047 family.

1307839:L21SP5 RS15850
gene id: 1307839:L21SP5_RS15850
uniprot id: A0A0S2I3C9
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS06600
gene id: 1307839:L21SP5_RS06600
uniprot id: A0A0S2HY16
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1307839:L21SP5 RS14880
gene id: 1307839:L21SP5_RS14880
uniprot id: A0A0S2I2V9
names: Similarity
messages: Belongs to the CapA family.

1307839:L21SP5 RS17050
gene id: 1307839:L21SP5_RS17050
uniprot id: A0A0S2I443
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS16770
gene id: 1307839:L21SP5_RS16770
uniprot id: A0A0S2I3K1
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS03050
gene id: 1307839:L21SP5_RS03050
uniprot id: A0A0S2HW58
names: Subcellular Location Annotation
messages: Cytoplasm

1307839:L21SP5 RS04635
gene id: 1307839:L21SP5_RS04635
uniprot id: A0A0S2HWY9
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1307839:L21SP5 RS13330
gene id: 1307839:L21SP5_RS13330
uniprot id: A0A0S2I217
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS09845
gene id: 1307839:L21SP5_RS09845
uniprot id: A0A0S2HZZ0
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1307839:L21SP5 RS16325
gene id: 1307839:L21SP5_RS16325
uniprot id: A0A0S2I3N4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1307839:L21SP5 RS15260
gene id: 1307839:L21SP5_RS15260
uniprot id: A0A0S2I3D3
names: Similarity
messages: Belongs to the RNA polymerase subunit omega family.

1307839:L21SP5 RS04545
gene id: 1307839:L21SP5_RS04545
uniprot id: A0A0S2HWX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1307839:L21SP5 RS12885
gene id: 1307839:L21SP5_RS12885
uniprot id: A0A0S2I1N4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1307839:L21SP5 RS11025
gene id: 1307839:L21SP5_RS11025
uniprot id: A0A0S2I0V8
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1307839:L21SP5 RS15210
gene id: 1307839:L21SP5_RS15210
uniprot id: A0A0S2I3E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1307839:L21SP5 RS13345
gene id: 1307839:L21SP5_RS13345
uniprot id: A0A0S2I215
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

1307839:L21SP5 RS07480
gene id: 1307839:L21SP5_RS07480
uniprot id: A0A0S2HYL3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS08250
gene id: 1307839:L21SP5_RS08250
uniprot id: A0A0S2HZ68
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS17560
gene id: 1307839:L21SP5_RS17560
uniprot id: A0A0S2I4M6
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS14975
gene id: 1307839:L21SP5_RS14975
uniprot id: A0A0S2I392
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1307839:L21SP5 RS14935
gene id: 1307839:L21SP5_RS14935
uniprot id: A0A0S2I342
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS11545
gene id: 1307839:L21SP5_RS11545
uniprot id: A0A0S2I160
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1307839:L21SP5 RS07200
gene id: 1307839:L21SP5_RS07200
uniprot id: A0A0S2HYR1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1307839:L21SP5 RS09900
gene id: 1307839:L21SP5_RS09900
uniprot id: A0A0S2I0F2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1307839:L21SP5 RS07110
gene id: 1307839:L21SP5_RS07110
uniprot id: A0A0S2HYE1
names: Similarity
messages: Belongs to the peptidase C1 family.

1307839:L21SP5 RS10445
gene id: 1307839:L21SP5_RS10445
uniprot id: A0A0S2I0D6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1307839:L21SP5 RS19185
gene id: 1307839:L21SP5_RS19185
uniprot id: A0A0S2I688
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1307839:L21SP5 RS03620
gene id: 1307839:L21SP5_RS03620
uniprot id: A0A0S2HWG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1307839:L21SP5 RS10160
gene id: 1307839:L21SP5_RS10160
uniprot id: A0A0S2HZX5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1307839:L21SP5 RS12935
gene id: 1307839:L21SP5_RS12935
uniprot id: A0A0S2I2K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1307839:L21SP5 RS14000
gene id: 1307839:L21SP5_RS14000
uniprot id: A0A0S2I2E0
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1307839:L21SP5 RS12190
gene id: 1307839:L21SP5_RS12190
uniprot id: A0A0S2I1P3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS15670
gene id: 1307839:L21SP5_RS15670
uniprot id: A0A0S2I480
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS10835
gene id: 1307839:L21SP5_RS10835
uniprot id: A0A0S2I0S2
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1307839:L21SP5 RS02150
gene id: 1307839:L21SP5_RS02150
uniprot id: A0A0S2HVQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1307839:L21SP5 RS06310
gene id: 1307839:L21SP5_RS06310
uniprot id: A0A0S2HY24
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1307839:L21SP5 RS14265
gene id: 1307839:L21SP5_RS14265
uniprot id: A0A0S2I2P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hemerythrin family.
messages: Membrane

1307839:L21SP5 RS17430
gene id: 1307839:L21SP5_RS17430
uniprot id: A0A0S2I3X1
names: Similarity
messages: Belongs to the ComB family.

1307839:L21SP5 RS18735
gene id: 1307839:L21SP5_RS18735
uniprot id: A0A0S2I572
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1307839:L21SP5 RS00125
gene id: 1307839:L21SP5_RS00125
uniprot id: A0A0S2HUQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1307839:L21SP5 RS10000
gene id: 1307839:L21SP5_RS10000
uniprot id: A0A0S2HZU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1307839:L21SP5 RS08815
gene id: 1307839:L21SP5_RS08815
uniprot id: A0A0S2HZJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1307839:L21SP5 RS01280
gene id: 1307839:L21SP5_RS01280
uniprot id: A0A0S2I0H3
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

1307839:L21SP5 RS18805
gene id: 1307839:L21SP5_RS18805
uniprot id: A0A0S2I4Z7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1307839:L21SP5 RS13845
gene id: 1307839:L21SP5_RS13845
uniprot id: A0A0S2I2B5
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1307839:L21SP5 RS01590
gene id: 1307839:L21SP5_RS01590
uniprot id: A0A0S2HVD8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1307839:L21SP5 RS01910
gene id: 1307839:L21SP5_RS01910
uniprot id: A0A0S2HVJ5
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1307839:L21SP5 RS18465
gene id: 1307839:L21SP5_RS18465
uniprot id: A0A0S2I4G7
names: Similarity
messages: Belongs to the DtxR/MntR family.

1307839:L21SP5 RS10005
gene id: 1307839:L21SP5_RS10005
uniprot id: A0A0S2I025
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1307839:L21SP5 RS18665
gene id: 1307839:L21SP5_RS18665
uniprot id: A0A0S2I4S2
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1307839:L21SP5 RS06420
gene id: 1307839:L21SP5_RS06420
uniprot id: A0A0S2HYA3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1307839:L21SP5 RS09530
gene id: 1307839:L21SP5_RS09530
uniprot id: A0A0S2HZT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS19080
gene id: 1307839:L21SP5_RS19080
uniprot id: A0A0S2I5C3
names: Subcellular Location Annotation
messages: Cytoplasm

1307839:L21SP5 RS01705
gene id: 1307839:L21SP5_RS01705
uniprot id: A0A0S2HVC1
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS12460
gene id: 1307839:L21SP5_RS12460
uniprot id: A0A0S2I1I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1307839:L21SP5 RS03435
gene id: 1307839:L21SP5_RS03435
uniprot id: A0A0S2HWG6
names: Similarity
messages: Belongs to the UPF0045 family.

1307839:L21SP5 RS12255
gene id: 1307839:L21SP5_RS12255
uniprot id: A0A0S2I162
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1307839:L21SP5 RS00355
gene id: 1307839:L21SP5_RS00355
uniprot id: A0A0S2HUT8
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

1307839:L21SP5 RS06755
gene id: 1307839:L21SP5_RS06755
uniprot id: A0A0S2HYG3
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS02600
gene id: 1307839:L21SP5_RS02600
uniprot id: A0A0S2HW28
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1307839:L21SP5 RS07205
gene id: 1307839:L21SP5_RS07205
uniprot id: A0A0S2HYD4
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1307839:L21SP5 RS12655
gene id: 1307839:L21SP5_RS12655
uniprot id: A0A0S2I1R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS18660
gene id: 1307839:L21SP5_RS18660
uniprot id: A0A0S2I563
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1307839:L21SP5 RS09840
gene id: 1307839:L21SP5_RS09840
uniprot id: A0A0S2HZR6
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS19390
gene id: 1307839:L21SP5_RS19390
uniprot id: A0A0S2I585
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1307839:L21SP5 RS09050
gene id: 1307839:L21SP5_RS09050
uniprot id: A0A0S2HZN4
names: Similarity
messages: Belongs to the peptidase M17 family.

1307839:L21SP5 RS07500
gene id: 1307839:L21SP5_RS07500
uniprot id: A0A0S2HYS3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS01890
gene id: 1307839:L21SP5_RS01890
uniprot id: A0A0S2HVK6
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1307839:L21SP5 RS09485
gene id: 1307839:L21SP5_RS09485
uniprot id: A0A0S2HZW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1307839:L21SP5 RS05280
gene id: 1307839:L21SP5_RS05280
uniprot id: A0A0S2HXM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1307839:L21SP5 RS10290
gene id: 1307839:L21SP5_RS10290
uniprot id: A0A0S2I042
names: Similarity
messages: Belongs to the peptidase M1 family.

1307839:L21SP5 RS18360
gene id: 1307839:L21SP5_RS18360
uniprot id: A0A0S2I536
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS12535
gene id: 1307839:L21SP5_RS12535
uniprot id: A0A0S2I2A6
names: Similarity
messages: Belongs to the glutamine synthetase family.

1307839:L21SP5 RS08180
gene id: 1307839:L21SP5_RS08180
uniprot id: A0A0S2HZ80
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS03820
gene id: 1307839:L21SP5_RS03820
uniprot id: A0A0S2HWM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1307839:L21SP5 RS04645
gene id: 1307839:L21SP5_RS04645
uniprot id: A0A0S2HX56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1307839:L21SP5 RS04960
gene id: 1307839:L21SP5_RS04960
uniprot id: A0A0S2HXH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1307839:L21SP5 RS06950
gene id: 1307839:L21SP5_RS06950
uniprot id: A0A0S2HYB5
names: Similarity
messages: Belongs to the GARS family.

1307839:L21SP5 RS18300
gene id: 1307839:L21SP5_RS18300
uniprot id: A0A0S2I4D6
names: Similarity
messages: Belongs to the UPF0162 family.

1307839:L21SP5 RS06400
gene id: 1307839:L21SP5_RS06400
uniprot id: A0A0S2HY10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1307839:L21SP5 RS05165
gene id: 1307839:L21SP5_RS05165
uniprot id: A0A0S2HXD6
names: Similarity
messages: Belongs to the UPF0145 family.

1307839:L21SP5 RS13865
gene id: 1307839:L21SP5_RS13865
uniprot id: A0A0S2I269
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1307839:L21SP5 RS10875
gene id: 1307839:L21SP5_RS10875
uniprot id: A0A0S2I0F9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1307839:L21SP5 RS07180
gene id: 1307839:L21SP5_RS07180
uniprot id: A0A0S2HYL2
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1307839:L21SP5 RS11445
gene id: 1307839:L21SP5_RS11445
uniprot id: A0A0S2I0M4
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1307839:L21SP5 RS06265
gene id: 1307839:L21SP5_RS06265
uniprot id: A0A0S2HY19
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS08720
gene id: 1307839:L21SP5_RS08720
uniprot id: A0A0S2HZ73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1307839:L21SP5 RS02250
gene id: 1307839:L21SP5_RS02250
uniprot id: A0A0S2I0H3
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

1307839:L21SP5 RS06220
gene id: 1307839:L21SP5_RS06220
uniprot id: A0A0S2HXS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS09650
gene id: 1307839:L21SP5_RS09650
uniprot id: A0A0S2I060
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS00030
gene id: 1307839:L21SP5_RS00030
uniprot id: A0A0S2HUD9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1307839:L21SP5 RS12835
gene id: 1307839:L21SP5_RS12835
uniprot id: A0A0S2I1Y0
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1307839:L21SP5 RS08795
gene id: 1307839:L21SP5_RS08795
uniprot id: A0A0S2HZJ9
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS13315
gene id: 1307839:L21SP5_RS13315
uniprot id: A0A0S2I265
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS08730
gene id: 1307839:L21SP5_RS08730
uniprot id: A0A0S2HZT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1307839:L21SP5 RS04730
gene id: 1307839:L21SP5_RS04730
uniprot id: A0A0S2HXD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1307839:L21SP5 RS04550
gene id: 1307839:L21SP5_RS04550
uniprot id: A0A0S2HWX4
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS18715
gene id: 1307839:L21SP5_RS18715
uniprot id: A0A0S2I566
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

1307839:L21SP5 RS06790
gene id: 1307839:L21SP5_RS06790
uniprot id: A0A0S2HYA6
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1307839:L21SP5 RS15400
gene id: 1307839:L21SP5_RS15400
uniprot id: A0A0S2I2U4
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1307839:L21SP5 RS09965
gene id: 1307839:L21SP5_RS09965
uniprot id: A0A0S2I0C9
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS15085
gene id: 1307839:L21SP5_RS15085
uniprot id: A0A0S2I3A7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1307839:L21SP5 RS12310
gene id: 1307839:L21SP5_RS12310
uniprot id: A0A0S2I1I9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1307839:L21SP5 RS16410
gene id: 1307839:L21SP5_RS16410
uniprot id: A0A0S2I3X8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1307839:L21SP5 RS00280
gene id: 1307839:L21SP5_RS00280
uniprot id: A0A0S2HUJ3
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1307839:L21SP5 RS11455
gene id: 1307839:L21SP5_RS11455
uniprot id: A0A0S2I136
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1307839:L21SP5 RS10265
gene id: 1307839:L21SP5_RS10265
uniprot id: A0A0S2I0A7
names: Similarity
messages: Belongs to the peptidase S51 family.

1307839:L21SP5 RS11420
gene id: 1307839:L21SP5_RS11420
uniprot id: A0A0S2I0Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1307839:L21SP5 RS10455
gene id: 1307839:L21SP5_RS10455
uniprot id: A0A0S2I0E6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1307839:L21SP5 RS02615
gene id: 1307839:L21SP5_RS02615
uniprot id: A0A0S2HVV2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1307839:L21SP5 RS02230
gene id: 1307839:L21SP5_RS02230
uniprot id: A0A0S2HVM7
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

1307839:L21SP5 RS08725
gene id: 1307839:L21SP5_RS08725
uniprot id: A0A0S2HZE7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1307839:L21SP5 RS08905
gene id: 1307839:L21SP5_RS08905
uniprot id: A0A0S2HZG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1307839:L21SP5 RS17610
gene id: 1307839:L21SP5_RS17610
uniprot id: A0A0S2I4D7
names: Similarity
messages: Belongs to the SCO1/2 family.

1307839:L21SP5 RS09460
gene id: 1307839:L21SP5_RS09460
uniprot id: A0A0S2I0N8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1307839:L21SP5 RS13505
gene id: 1307839:L21SP5_RS13505
uniprot id: A0A0S2I240
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

1307839:L21SP5 RS13735
gene id: 1307839:L21SP5_RS13735
uniprot id: A0A0S2I2Z5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1307839:L21SP5 RS14205
gene id: 1307839:L21SP5_RS14205
uniprot id: A0A0S2I2R0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

1307839:L21SP5 RS02300
gene id: 1307839:L21SP5_RS02300
uniprot id: A0A0S2HVP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1307839:L21SP5 RS10950
gene id: 1307839:L21SP5_RS10950
uniprot id: A0A0S2I0G6
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS17100
gene id: 1307839:L21SP5_RS17100
uniprot id: A0A0S2I4G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

1307839:L21SP5 RS09825
gene id: 1307839:L21SP5_RS09825
uniprot id: A0A0S2I031
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1307839:L21SP5 RS12395
gene id: 1307839:L21SP5_RS12395
uniprot id: A0A0S2I1G1
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS15375
gene id: 1307839:L21SP5_RS15375
uniprot id: A0A0S2I2U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS09220
gene id: 1307839:L21SP5_RS09220
uniprot id: A0A0S2HZE3
names: Similarity
messages: Belongs to the DtxR/MntR family.

1307839:L21SP5 RS17250
gene id: 1307839:L21SP5_RS17250
uniprot id: A0A0S2I3T9
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1307839:L21SP5 RS13095
gene id: 1307839:L21SP5_RS13095
uniprot id: A0A0S2I2N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1307839:L21SP5 RS13910
gene id: 1307839:L21SP5_RS13910
uniprot id: A0A0S2I2G4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS01750
gene id: 1307839:L21SP5_RS01750
uniprot id: A0A0S2HVF8
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1307839:L21SP5 RS01520
gene id: 1307839:L21SP5_RS01520
uniprot id: A0A0S2HV75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1307839:L21SP5 RS11645
gene id: 1307839:L21SP5_RS11645
uniprot id: A0A0S2I100
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1307839:L21SP5 RS17495
gene id: 1307839:L21SP5_RS17495
uniprot id: A0A0S2I4I6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS19335
gene id: 1307839:L21SP5_RS19335
uniprot id: A0A0S2I5G1
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1307839:L21SP5 RS12520
gene id: 1307839:L21SP5_RS12520
uniprot id: A0A0S2I1C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADP/ATP translocase tlc family.
messages: Membrane

1307839:L21SP5 RS07230
gene id: 1307839:L21SP5_RS07230
uniprot id: A0A0S2HYL7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1307839:L21SP5 RS18685
gene id: 1307839:L21SP5_RS18685
uniprot id: A0A0S2I4Q3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1307839:L21SP5 RS09190
gene id: 1307839:L21SP5_RS09190
uniprot id: A0A0S2HZH0
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1307839:L21SP5 RS06340
gene id: 1307839:L21SP5_RS06340
uniprot id: A0A0S2HXW6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1307839:L21SP5 RS10470
gene id: 1307839:L21SP5_RS10470
uniprot id: A0A0S2I076
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS11165
gene id: 1307839:L21SP5_RS11165
uniprot id: A0A0S2I0T3
names: Similarity
messages: Belongs to the AIR synthase family.

1307839:L21SP5 RS17640
gene id: 1307839:L21SP5_RS17640
uniprot id: A0A0S2I4P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1307839:L21SP5 RS11475
gene id: 1307839:L21SP5_RS11475
uniprot id: A0A0S2I0U8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS03785
gene id: 1307839:L21SP5_RS03785
uniprot id: A0A0S2HWG5
names: Similarity
messages: Belongs to the cytochrome c-552 family.

1307839:L21SP5 RS15390
gene id: 1307839:L21SP5_RS15390
uniprot id: A0A0S2I320
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1307839:L21SP5 RS19165
gene id: 1307839:L21SP5_RS19165
uniprot id: A0A0S2I4Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool.
messages: Golgi apparatus
messages: Homooctamer, including four polyglutamate binding sites. The subunits are arranged as a tetramer of dimers, and form a planar ring-shaped structure.
messages: In the C-terminal section; belongs to the cyclodeaminase/cyclohydrolase family.
messages: In the N-terminal section; belongs to the formiminotransferase family.
messages: centriole

1307839:L21SP5 RS12040
gene id: 1307839:L21SP5_RS12040
uniprot id: A0A0S2I122
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1307839:L21SP5 RS11075
gene id: 1307839:L21SP5_RS11075
uniprot id: A0A0S2I1J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

1307839:L21SP5 RS04285
gene id: 1307839:L21SP5_RS04285
uniprot id: A0A0S2HWX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1307839:L21SP5 RS00270
gene id: 1307839:L21SP5_RS00270
uniprot id: A0A0S2HUH9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1307839:L21SP5 RS03770
gene id: 1307839:L21SP5_RS03770
uniprot id: A0A0S2HWT2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1307839:L21SP5 RS09180
gene id: 1307839:L21SP5_RS09180
uniprot id: A0A0S2HZQ5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1307839:L21SP5 RS09505
gene id: 1307839:L21SP5_RS09505
uniprot id: A0A0S2I075
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1307839:L21SP5 RS00140
gene id: 1307839:L21SP5_RS00140
uniprot id: A0A0S2HUH6
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1307839:L21SP5 RS12030
gene id: 1307839:L21SP5_RS12030
uniprot id: A0A0S2I199
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1307839:L21SP5 RS08645
gene id: 1307839:L21SP5_RS08645
uniprot id: A0A0S2HZC7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1307839:L21SP5 RS17850
gene id: 1307839:L21SP5_RS17850
uniprot id: A0A0S2I5K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1307839:L21SP5 RS11460
gene id: 1307839:L21SP5_RS11460
uniprot id: A0A0S2I1Q2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1307839:L21SP5 RS06225
gene id: 1307839:L21SP5_RS06225
uniprot id: A0A0S2HXX9
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS14965
gene id: 1307839:L21SP5_RS14965
uniprot id: A0A0S2I2K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1307839:L21SP5 RS15055
gene id: 1307839:L21SP5_RS15055
uniprot id: A0A0S2I3A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1307839:L21SP5 RS04150
gene id: 1307839:L21SP5_RS04150
uniprot id: A0A0S2HWW3
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS13640
gene id: 1307839:L21SP5_RS13640
uniprot id: A0A0S2I1Z9
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1307839:L21SP5 RS02625
gene id: 1307839:L21SP5_RS02625
uniprot id: A0A0S2HVV9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1307839:L21SP5 RS19345
gene id: 1307839:L21SP5_RS19345
uniprot id: A0A0S2I6B5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1307839:L21SP5 RS07320
gene id: 1307839:L21SP5_RS07320
uniprot id: A0A0S2HYH8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1307839:L21SP5 RS15645
gene id: 1307839:L21SP5_RS15645
uniprot id: A0A0S2I3J1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1307839:L21SP5 RS03825
gene id: 1307839:L21SP5_RS03825
uniprot id: A0A0S2HWP0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1307839:L21SP5 RS16225
gene id: 1307839:L21SP5_RS16225
uniprot id: A0A0S2I4J1
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1307839:L21SP5 RS10660
gene id: 1307839:L21SP5_RS10660
uniprot id: A0A0S2I0P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1307839:L21SP5 RS06620
gene id: 1307839:L21SP5_RS06620
uniprot id: A0A0S2HY38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1307839:L21SP5 RS11660
gene id: 1307839:L21SP5_RS11660
uniprot id: A0A0S2I1I7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1307839:L21SP5 RS05040
gene id: 1307839:L21SP5_RS05040
uniprot id: A0A0S2I2T4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1307839:L21SP5 RS08235
gene id: 1307839:L21SP5_RS08235
uniprot id: A0A0S2HZ74
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1307839:L21SP5 RS09160
gene id: 1307839:L21SP5_RS09160
uniprot id: A0A0S2HZR4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1307839:L21SP5 RS12880
gene id: 1307839:L21SP5_RS12880
uniprot id: A0A0S2I1X2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS09675
gene id: 1307839:L21SP5_RS09675
uniprot id: A0A0S2I015
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1307839:L21SP5 RS17620
gene id: 1307839:L21SP5_RS17620
uniprot id: A0A0S2I4E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS14810
gene id: 1307839:L21SP5_RS14810
uniprot id: A0A0S2I2X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1307839:L21SP5 RS12550
gene id: 1307839:L21SP5_RS12550
uniprot id: A0A0S2I1J1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1307839:L21SP5 RS09880
gene id: 1307839:L21SP5_RS09880
uniprot id: A0A0S2I041
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS12485
gene id: 1307839:L21SP5_RS12485
uniprot id: A0A0S2I1L1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1307839:L21SP5 RS04200
gene id: 1307839:L21SP5_RS04200
uniprot id: A0A0S2HXG0
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

1307839:L21SP5 RS16795
gene id: 1307839:L21SP5_RS16795
uniprot id: A0A0S2I3T8
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1307839:L21SP5 RS17000
gene id: 1307839:L21SP5_RS17000
uniprot id: A0A0S2I4A3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1307839:L21SP5 RS18535
gene id: 1307839:L21SP5_RS18535
uniprot id: A0A0S2I4M5
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS12095
gene id: 1307839:L21SP5_RS12095
uniprot id: A0A0S2I130
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

1307839:L21SP5 RS01745
gene id: 1307839:L21SP5_RS01745
uniprot id: A0A0S2HVE0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1307839:L21SP5 RS05080
gene id: 1307839:L21SP5_RS05080
uniprot id: A0A0S2HXC5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1307839:L21SP5 RS14040
gene id: 1307839:L21SP5_RS14040
uniprot id: A0A0S2I2N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1307839:L21SP5 RS16485
gene id: 1307839:L21SP5_RS16485
uniprot id: A0A0S2I3R9
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1307839:L21SP5 RS04520
gene id: 1307839:L21SP5_RS04520
uniprot id: A0A0S2HWZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1307839:L21SP5 RS18355
gene id: 1307839:L21SP5_RS18355
uniprot id: A0A0S2I4K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1307839:L21SP5 RS13560
gene id: 1307839:L21SP5_RS13560
uniprot id: A0A0S2I1Y3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1307839:L21SP5 RS06975
gene id: 1307839:L21SP5_RS06975
uniprot id: A0A0S2HYL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

1307839:L21SP5 RS05785
gene id: 1307839:L21SP5_RS05785
uniprot id: A0A0S2HXW0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1307839:L21SP5 RS09300
gene id: 1307839:L21SP5_RS09300
uniprot id: A0A0S2HZN8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS12890
gene id: 1307839:L21SP5_RS12890
uniprot id: A0A0S2I1T9
names: Similarity
messages: Belongs to the citrate synthase family.

1307839:L21SP5 RS13810
gene id: 1307839:L21SP5_RS13810
uniprot id: A0A0S2I2I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS13125
gene id: 1307839:L21SP5_RS13125
uniprot id: A0A0S2I1S2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1307839:L21SP5 RS09455
gene id: 1307839:L21SP5_RS09455
uniprot id: A0A0S2HZW0
names: Similarity
messages: Belongs to the sigma-54 factor family.

1307839:L21SP5 RS11355
gene id: 1307839:L21SP5_RS11355
uniprot id: A0A0S2I0X3
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1307839:L21SP5 RS12280
gene id: 1307839:L21SP5_RS12280
uniprot id: A0A0S2I166
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1307839:L21SP5 RS15530
gene id: 1307839:L21SP5_RS15530
uniprot id: A0A0S2I3D8
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1307839:L21SP5 RS10700
gene id: 1307839:L21SP5_RS10700
uniprot id: A0A0S2I0I8
names: Similarity
messages: Belongs to the universal stress protein A family.

1307839:L21SP5 RS13250
gene id: 1307839:L21SP5_RS13250
uniprot id: A0A0S2I1Z8
names: Similarity
messages: Belongs to the Dps family.

1307839:L21SP5 RS02570
gene id: 1307839:L21SP5_RS02570
uniprot id: A0A0S2HVU1
names: Similarity
messages: Belongs to the Skp family.

1307839:L21SP5 RS14420
gene id: 1307839:L21SP5_RS14420
uniprot id: A0A0S2I2H1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1307839:L21SP5 RS02610
gene id: 1307839:L21SP5_RS02610
uniprot id: A0A0S2HW03
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1307839:L21SP5 RS18125
gene id: 1307839:L21SP5_RS18125
uniprot id: A0A0S2I4X9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1307839:L21SP5 RS18950
gene id: 1307839:L21SP5_RS18950
uniprot id: A0A0S2I5F0
names: Similarity
messages: Belongs to the hemerythrin family.

1307839:L21SP5 RS06290
gene id: 1307839:L21SP5_RS06290
uniprot id: A0A0S2HXX6
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

1307839:L21SP5 RS02510
gene id: 1307839:L21SP5_RS02510
uniprot id: A0A0S2HVV0
names: Similarity
messages: Belongs to the PRORSD1 family.

1307839:L21SP5 RS02875
gene id: 1307839:L21SP5_RS02875
uniprot id: A0A0S2HW37
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1307839:L21SP5 RS18265
gene id: 1307839:L21SP5_RS18265
uniprot id: A0A0S2I4Q0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1307839:L21SP5 RS06330
gene id: 1307839:L21SP5_RS06330
uniprot id: A0A0S2HXZ2
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS18415
gene id: 1307839:L21SP5_RS18415
uniprot id: A0A0S2I4R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1307839:L21SP5 RS04120
gene id: 1307839:L21SP5_RS04120
uniprot id: A0A0S2HXE6
names: Similarity
messages: Belongs to the LOG family.

1307839:L21SP5 RS08655
gene id: 1307839:L21SP5_RS08655
uniprot id: A0A0S2HZG1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1307839:L21SP5 RS05770
gene id: 1307839:L21SP5_RS05770
uniprot id: A0A0S2HXM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1307839:L21SP5 RS08075
gene id: 1307839:L21SP5_RS08075
uniprot id: A0A0S2HZ49
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1307839:L21SP5 RS13475
gene id: 1307839:L21SP5_RS13475
uniprot id: A0A0S2I299
names: Similarity
messages: Belongs to the TrpF family.

1307839:L21SP5 RS14600
gene id: 1307839:L21SP5_RS14600
uniprot id: A0A0S2I2Z7
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1307839:L21SP5 RS14195
gene id: 1307839:L21SP5_RS14195
uniprot id: A0A0S2I254
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1307839:L21SP5 RS09245
gene id: 1307839:L21SP5_RS09245
uniprot id: A0A0S2HZS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1307839:L21SP5 RS04650
gene id: 1307839:L21SP5_RS04650
uniprot id: A0A0S2HX04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1307839:L21SP5 RS10055
gene id: 1307839:L21SP5_RS10055
uniprot id: A0A0S2I0I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1307839:L21SP5 RS08700
gene id: 1307839:L21SP5_RS08700
uniprot id: A0A0S2HZB1
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS05905
gene id: 1307839:L21SP5_RS05905
uniprot id: A0A0S2HXL6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS08810
gene id: 1307839:L21SP5_RS08810
uniprot id: A0A0S2HZV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1307839:L21SP5 RS10195
gene id: 1307839:L21SP5_RS10195
uniprot id: A0A0S2I098
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1307839:L21SP5 RS11755
gene id: 1307839:L21SP5_RS11755
uniprot id: A0A0S2I192
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1307839:L21SP5 RS15585
gene id: 1307839:L21SP5_RS15585
uniprot id: A0A0S2I3M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1307839:L21SP5 RS13860
gene id: 1307839:L21SP5_RS13860
uniprot id: A0A0S2I2L6
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1307839:L21SP5 RS04420
gene id: 1307839:L21SP5_RS04420
uniprot id: A0A0S2HWX6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1307839:L21SP5 RS11315
gene id: 1307839:L21SP5_RS11315
uniprot id: A0A0S2I1M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS00070
gene id: 1307839:L21SP5_RS00070
uniprot id: A0A0S2HUE3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1307839:L21SP5 RS04355
gene id: 1307839:L21SP5_RS04355
uniprot id: A0A0S2HWS8
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

1307839:L21SP5 RS16220
gene id: 1307839:L21SP5_RS16220
uniprot id: A0A0S2I3Z7
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1307839:L21SP5 RS05110
gene id: 1307839:L21SP5_RS05110
uniprot id: A0A0S2HX95
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS10105
gene id: 1307839:L21SP5_RS10105
uniprot id: A0A0S2I082
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1307839:L21SP5 RS12525
gene id: 1307839:L21SP5_RS12525
uniprot id: A0A0S2I1I5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1307839:L21SP5 RS17625
gene id: 1307839:L21SP5_RS17625
uniprot id: A0A0S2I4D5
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS05665
gene id: 1307839:L21SP5_RS05665
uniprot id: A0A0S2HYB4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1307839:L21SP5 RS09035
gene id: 1307839:L21SP5_RS09035
uniprot id: A0A0S2HZP2
names: Similarity
messages: Belongs to the peptidase C1 family.

1307839:L21SP5 RS17635
gene id: 1307839:L21SP5_RS17635
uniprot id: A0A0S2I471
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1307839:L21SP5 RS06715
gene id: 1307839:L21SP5_RS06715
uniprot id: A0A0S2HY72
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS18795
gene id: 1307839:L21SP5_RS18795
uniprot id: A0A0S2I5C7
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1307839:L21SP5 RS09215
gene id: 1307839:L21SP5_RS09215
uniprot id: A0A0S2HZL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1307839:L21SP5 RS05335
gene id: 1307839:L21SP5_RS05335
uniprot id: A0A0S2HXC1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1307839:L21SP5 RS13720
gene id: 1307839:L21SP5_RS13720
uniprot id: A0A0S2I223
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

1307839:L21SP5 RS15680
gene id: 1307839:L21SP5_RS15680
uniprot id: A0A0S2I3B1
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS04365
gene id: 1307839:L21SP5_RS04365
uniprot id: A0A0S2HWW4
names: Similarity
messages: Belongs to the SusD family.

1307839:L21SP5 RS00170
gene id: 1307839:L21SP5_RS00170
uniprot id: A0A0S2HUQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1307839:L21SP5 RS14960
gene id: 1307839:L21SP5_RS14960
uniprot id: A0A0S2I2X6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1307839:L21SP5 RS07115
gene id: 1307839:L21SP5_RS07115
uniprot id: A0A0S2HYG7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1307839:L21SP5 RS11295
gene id: 1307839:L21SP5_RS11295
uniprot id: A0A0S2I0Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS08560
gene id: 1307839:L21SP5_RS08560
uniprot id: A0A0S2HZ51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1307839:L21SP5 RS18820
gene id: 1307839:L21SP5_RS18820
uniprot id: A0A0S2I582
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1307839:L21SP5 RS17825
gene id: 1307839:L21SP5_RS17825
uniprot id: A0A0S2I4P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1307839:L21SP5 RS17360
gene id: 1307839:L21SP5_RS17360
uniprot id: A0A0S2I4L3
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1307839:L21SP5 RS15965
gene id: 1307839:L21SP5_RS15965
uniprot id: A0A0S2I3P2
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1307839:L21SP5 RS13590
gene id: 1307839:L21SP5_RS13590
uniprot id: A0A0S2I2B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS09705
gene id: 1307839:L21SP5_RS09705
uniprot id: A0A0S2I009
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1307839:L21SP5 RS18675
gene id: 1307839:L21SP5_RS18675
uniprot id: A0A0S2I4X2
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1307839:L21SP5 RS11330
gene id: 1307839:L21SP5_RS11330
uniprot id: A0A0S2I0R8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS08585
gene id: 1307839:L21SP5_RS08585
uniprot id: A0A0S2HZ93
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1307839:L21SP5 RS01475
gene id: 1307839:L21SP5_RS01475
uniprot id: A0A0S2HVF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1307839:L21SP5 RS07585
gene id: 1307839:L21SP5_RS07585
uniprot id: A0A0S2HYM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1307839:L21SP5 RS17380
gene id: 1307839:L21SP5_RS17380
uniprot id: A0A0S2I464
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1307839:L21SP5 RS11235
gene id: 1307839:L21SP5_RS11235
uniprot id: A0A0S2I1L8
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1307839:L21SP5 RS03415
gene id: 1307839:L21SP5_RS03415
uniprot id: A0A0S2HWA9
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS05955
gene id: 1307839:L21SP5_RS05955
uniprot id: A0A0S2HXP0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1307839:L21SP5 RS11360
gene id: 1307839:L21SP5_RS11360
uniprot id: A0A0S2I104
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1307839:L21SP5 RS13540
gene id: 1307839:L21SP5_RS13540
uniprot id: A0A0S2I2F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1307839:L21SP5 RS17305
gene id: 1307839:L21SP5_RS17305
uniprot id: A0A0S2I413
names: Similarity
messages: Belongs to the peptidase S9A family.

1307839:L21SP5 RS15065
gene id: 1307839:L21SP5_RS15065
uniprot id: A0A0S2I364
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1307839:L21SP5 RS17365
gene id: 1307839:L21SP5_RS17365
uniprot id: A0A0S2I599
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1307839:L21SP5 RS07690
gene id: 1307839:L21SP5_RS07690
uniprot id: A0A0S2HYN1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1307839:L21SP5 RS08200
gene id: 1307839:L21SP5_RS08200
uniprot id: A0A0S2HZ35
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1307839:L21SP5 RS12980
gene id: 1307839:L21SP5_RS12980
uniprot id: A0A0S2I249
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1307839:L21SP5 RS16525
gene id: 1307839:L21SP5_RS16525
uniprot id: A0A0S2I3I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS18425
gene id: 1307839:L21SP5_RS18425
uniprot id: A0A0S2I4T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS19300
gene id: 1307839:L21SP5_RS19300
uniprot id: A0A0S2I545
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1307839:L21SP5 RS14620
gene id: 1307839:L21SP5_RS14620
uniprot id: A0A0S2I2Q2
names: Similarity
messages: Belongs to the DSD1 family.

1307839:L21SP5 RS15090
gene id: 1307839:L21SP5_RS15090
uniprot id: A0A0S2I370
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1307839:L21SP5 RS08590
gene id: 1307839:L21SP5_RS08590
uniprot id: A0A0S2HZ41
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS07255
gene id: 1307839:L21SP5_RS07255
uniprot id: A0A0S2HYM6
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS17630
gene id: 1307839:L21SP5_RS17630
uniprot id: A0A0S2I4L2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1307839:L21SP5 RS05575
gene id: 1307839:L21SP5_RS05575
uniprot id: A0A0S2HXL3
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1307839:L21SP5 RS10115
gene id: 1307839:L21SP5_RS10115
uniprot id: A0A0S2I085
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1307839:L21SP5 RS10710
gene id: 1307839:L21SP5_RS10710
uniprot id: A0A0S2I0R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1307839:L21SP5 RS13790
gene id: 1307839:L21SP5_RS13790
uniprot id: A0A0S2I258
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1307839:L21SP5 RS17280
gene id: 1307839:L21SP5_RS17280
uniprot id: A0A0S2I455
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1307839:L21SP5 RS17005
gene id: 1307839:L21SP5_RS17005
uniprot id: A0A0S2I2T4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1307839:L21SP5 RS15415
gene id: 1307839:L21SP5_RS15415
uniprot id: A0A0S2I3F8
names: Similarity
messages: Belongs to the fabD family.

1307839:L21SP5 RS12560
gene id: 1307839:L21SP5_RS12560
uniprot id: A0A0S2I1I1
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

1307839:L21SP5 RS06320
gene id: 1307839:L21SP5_RS06320
uniprot id: A0A0S2HXZ9
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS13915
gene id: 1307839:L21SP5_RS13915
uniprot id: A0A0S2I2G3
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1307839:L21SP5 RS06460
gene id: 1307839:L21SP5_RS06460
uniprot id: A0A0S2HY21
names: Subcellular Location Annotation
messages: Cytoplasm

1307839:L21SP5 RS09580
gene id: 1307839:L21SP5_RS09580
uniprot id: A0A0S2HZV7
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

1307839:L21SP5 RS05605
gene id: 1307839:L21SP5_RS05605
uniprot id: A0A0S2HXH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1307839:L21SP5 RS11980
gene id: 1307839:L21SP5_RS11980
uniprot id: A0A0S2I189
names: Similarity
messages: Belongs to the peptidase S41A family.

1307839:L21SP5 RS12845
gene id: 1307839:L21SP5_RS12845
uniprot id: A0A0S2I1M5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1307839:L21SP5 RS02370
gene id: 1307839:L21SP5_RS02370
uniprot id: A0A0S2I2T4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1307839:L21SP5 RS16390
gene id: 1307839:L21SP5_RS16390
uniprot id: A0A0S2I3K2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1307839:L21SP5 RS11150
gene id: 1307839:L21SP5_RS11150
uniprot id: A0A0S2I0X5
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS01865
gene id: 1307839:L21SP5_RS01865
uniprot id: A0A0S2HVE7
names: Similarity
messages: Belongs to the UPF0166 family.

1307839:L21SP5 RS13875
gene id: 1307839:L21SP5_RS13875
uniprot id: A0A0S2I1Y5
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1307839:L21SP5 RS08735
gene id: 1307839:L21SP5_RS08735
uniprot id: A0A0S2HZI6
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1307839:L21SP5 RS04490
gene id: 1307839:L21SP5_RS04490
uniprot id: A0A0S2HX63
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS14995
gene id: 1307839:L21SP5_RS14995
uniprot id: A0A0S2I2Q6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1307839:L21SP5 RS06465
gene id: 1307839:L21SP5_RS06465
uniprot id: A0A0S2HY60
names: Subcellular Location Annotation
messages: Cytoplasm

1307839:L21SP5 RS16470
gene id: 1307839:L21SP5_RS16470
uniprot id: A0A0S2I3L9
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1307839:L21SP5 RS15100
gene id: 1307839:L21SP5_RS15100
uniprot id: A0A0S2I335
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1307839:L21SP5 RS07485
gene id: 1307839:L21SP5_RS07485
uniprot id: A0A0S2HYQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS06185
gene id: 1307839:L21SP5_RS06185
uniprot id: A0A0S2HY08
names: Similarity
messages: Belongs to the UPF0251 family.

1307839:L21SP5 RS06130
gene id: 1307839:L21SP5_RS06130
uniprot id: A0A0S2HY03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1307839:L21SP5 RS09445
gene id: 1307839:L21SP5_RS09445
uniprot id: A0A0S2HZJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1307839:L21SP5 RS03410
gene id: 1307839:L21SP5_RS03410
uniprot id: A0A0S2HWE4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

1307839:L21SP5 RS14480
gene id: 1307839:L21SP5_RS14480
uniprot id: A0A0S2I2N0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1307839:L21SP5 RS18015
gene id: 1307839:L21SP5_RS18015
uniprot id: A0A0S2HXE8
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

1307839:L21SP5 RS06490
gene id: 1307839:L21SP5_RS06490
uniprot id: A0A0S2HXY9
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1307839:L21SP5 RS16450
gene id: 1307839:L21SP5_RS16450
uniprot id: A0A0S2I404
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1307839:L21SP5 RS15010
gene id: 1307839:L21SP5_RS15010
uniprot id: A0A0S2I3W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1307839:L21SP5 RS04875
gene id: 1307839:L21SP5_RS04875
uniprot id: A0A0S2HXA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

1307839:L21SP5 RS04505
gene id: 1307839:L21SP5_RS04505
uniprot id: A0A0S2HX13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1307839:L21SP5 RS09500
gene id: 1307839:L21SP5_RS09500
uniprot id: A0A0S2HZU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1307839:L21SP5 RS16880
gene id: 1307839:L21SP5_RS16880
uniprot id: A0A0S2I3X5
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

1307839:L21SP5 RS17185
gene id: 1307839:L21SP5_RS17185
uniprot id: A0A0S2I575
names: Similarity
messages: Belongs to the peptidase S26 family.

1307839:L21SP5 RS00205
gene id: 1307839:L21SP5_RS00205
uniprot id: A0A0S2HUV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1307839:L21SP5 RS09520
gene id: 1307839:L21SP5_RS09520
uniprot id: A0A0S2HZS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Membrane

1307839:L21SP5 RS09645
gene id: 1307839:L21SP5_RS09645
uniprot id: A0A0S2HZZ4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS01680
gene id: 1307839:L21SP5_RS01680
uniprot id: A0A0S2HVM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS02885
gene id: 1307839:L21SP5_RS02885
uniprot id: A0A0S2HW35
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1307839:L21SP5 RS14800
gene id: 1307839:L21SP5_RS14800
uniprot id: A0A0S2I2U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS09490
gene id: 1307839:L21SP5_RS09490
uniprot id: A0A0S2HZY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1307839:L21SP5 RS10440
gene id: 1307839:L21SP5_RS10440
uniprot id: A0A0S2I0F5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1307839:L21SP5 RS16790
gene id: 1307839:L21SP5_RS16790
uniprot id: A0A0S2I4C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1307839:L21SP5 RS14540
gene id: 1307839:L21SP5_RS14540
uniprot id: A0A0S2I2M8
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1307839:L21SP5 RS09495
gene id: 1307839:L21SP5_RS09495
uniprot id: A0A0S2HZM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1307839:L21SP5 RS05415
gene id: 1307839:L21SP5_RS05415
uniprot id: A0A0S2HXE9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS11465
gene id: 1307839:L21SP5_RS11465
uniprot id: A0A0S2I0Z1
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1307839:L21SP5 RS03395
gene id: 1307839:L21SP5_RS03395
uniprot id: A0A0S2HWA0
names: Similarity
messages: Belongs to the ParB family.

1307839:L21SP5 RS07100
gene id: 1307839:L21SP5_RS07100
uniprot id: A0A0S2HYJ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1307839:L21SP5 RS14185
gene id: 1307839:L21SP5_RS14185
uniprot id: A0A0S2I2C6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1307839:L21SP5 RS01880
gene id: 1307839:L21SP5_RS01880
uniprot id: A0A0S2HVN7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1307839:L21SP5 RS08625
gene id: 1307839:L21SP5_RS08625
uniprot id: A0A0S2HZA3
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS14500
gene id: 1307839:L21SP5_RS14500
uniprot id: A0A0S2I2J0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS04790
gene id: 1307839:L21SP5_RS04790
uniprot id: A0A0S2HX21
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

1307839:L21SP5 RS10510
gene id: 1307839:L21SP5_RS10510
uniprot id: A0A0S2I0K9
names: Similarity
messages: Belongs to the FemABX family.

1307839:L21SP5 RS11390
gene id: 1307839:L21SP5_RS11390
uniprot id: A0A0S2I128
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS13960
gene id: 1307839:L21SP5_RS13960
uniprot id: A0A0S2I2L7
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS15315
gene id: 1307839:L21SP5_RS15315
uniprot id: A0A0S2I3A6
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1307839:L21SP5 RS05640
gene id: 1307839:L21SP5_RS05640
uniprot id: A0A0S2HXL0
names: Similarity
messages: Belongs to the peptidase C69 family.

1307839:L21SP5 RS16580
gene id: 1307839:L21SP5_RS16580
uniprot id: A0A0S2I3X7
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1307839:L21SP5 RS18705
gene id: 1307839:L21SP5_RS18705
uniprot id: A0A0S2I604
names: Subcellular Location Annotation
messages: Secreted

1307839:L21SP5 RS08605
gene id: 1307839:L21SP5_RS08605
uniprot id: A0A0S2I064
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1307839:L21SP5 RS09755
gene id: 1307839:L21SP5_RS09755
uniprot id: A0A0S2HZX0
names: Similarity
messages: Belongs to the UPF0045 family.

1307839:L21SP5 RS13610
gene id: 1307839:L21SP5_RS13610
uniprot id: A0A0S2I1U5
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1307839:L21SP5 RS17700
gene id: 1307839:L21SP5_RS17700
uniprot id: A0A0S2I4F2
names: Similarity
messages: Belongs to the peptidase C1 family.

1307839:L21SP5 RS08295
gene id: 1307839:L21SP5_RS08295
uniprot id: A0A0S2HZA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1307839:L21SP5 RS18515
gene id: 1307839:L21SP5_RS18515
uniprot id: A0A0S2I4N9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1307839:L21SP5 RS11510
gene id: 1307839:L21SP5_RS11510
uniprot id: A0A0S2I102
names: Similarity
messages: Belongs to the peptidase S41A family.

1307839:L21SP5 RS00100
gene id: 1307839:L21SP5_RS00100
uniprot id: A0A0S2HUE6
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1307839:L21SP5 RS16835
gene id: 1307839:L21SP5_RS16835
uniprot id: A0A0S2I3W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1307839:L21SP5 RS07460
gene id: 1307839:L21SP5_RS07460
uniprot id: A0A0S2HYT9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1307839:L21SP5 RS04115
gene id: 1307839:L21SP5_RS04115
uniprot id: A0A0S2HWR7
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS06505
gene id: 1307839:L21SP5_RS06505
uniprot id: A0A0S2HY93
names: Subunit
messages: Monomer.

1307839:L21SP5 RS13800
gene id: 1307839:L21SP5_RS13800
uniprot id: A0A0S2I1W7
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS11115
gene id: 1307839:L21SP5_RS11115
uniprot id: A0A0S2I0P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1307839:L21SP5 RS03700
gene id: 1307839:L21SP5_RS03700
uniprot id: A0A0S2HWI3
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS14575
gene id: 1307839:L21SP5_RS14575
uniprot id: A0A0S2I316
names: Similarity
messages: Belongs to the peptidase S9C family.

1307839:L21SP5 RS14180
gene id: 1307839:L21SP5_RS14180
uniprot id: A0A0S2I2T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1307839:L21SP5 RS06610
gene id: 1307839:L21SP5_RS06610
uniprot id: A0A0S2HYB6
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS06335
gene id: 1307839:L21SP5_RS06335
uniprot id: A0A0S2HXX0
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS15000
gene id: 1307839:L21SP5_RS15000
uniprot id: A0A0S2I369
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1307839:L21SP5 RS14035
gene id: 1307839:L21SP5_RS14035
uniprot id: A0A0S2I283
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1307839:L21SP5 RS08995
gene id: 1307839:L21SP5_RS08995
uniprot id: A0A0S2HZH9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS10205
gene id: 1307839:L21SP5_RS10205
uniprot id: A0A0S2I0G3
names: Similarity
messages: Belongs to the aspartokinase family.

1307839:L21SP5 RS11340
gene id: 1307839:L21SP5_RS11340
uniprot id: A0A0S2I0V4
names: Similarity
messages: Belongs to the universal stress protein A family.

1307839:L21SP5 RS05505
gene id: 1307839:L21SP5_RS05505
uniprot id: A0A0S2HXN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1307839:L21SP5 RS18720
gene id: 1307839:L21SP5_RS18720
uniprot id: A0A0S2I4Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1307839:L21SP5 RS13920
gene id: 1307839:L21SP5_RS13920
uniprot id: A0A0S2I2B1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1307839:L21SP5 RS03705
gene id: 1307839:L21SP5_RS03705
uniprot id: A0A0S2HWF0
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS11480
gene id: 1307839:L21SP5_RS11480
uniprot id: A0A0S2I0Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1307839:L21SP5 RS03730
gene id: 1307839:L21SP5_RS03730
uniprot id: A0A0S2HX68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1307839:L21SP5 RS02990
gene id: 1307839:L21SP5_RS02990
uniprot id: A0A0S2HW32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1307839:L21SP5 RS03815
gene id: 1307839:L21SP5_RS03815
uniprot id: A0A0S2HWN5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1307839:L21SP5 RS04360
gene id: 1307839:L21SP5_RS04360
uniprot id: A0A0S2HWV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1307839:L21SP5 RS15095
gene id: 1307839:L21SP5_RS15095
uniprot id: A0A0S2I2Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1307839:L21SP5 RS15045
gene id: 1307839:L21SP5_RS15045
uniprot id: A0A0S2I2L9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1307839:L21SP5 RS00325
gene id: 1307839:L21SP5_RS00325
uniprot id: A0A0S2HUU4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1307839:L21SP5 RS04485
gene id: 1307839:L21SP5_RS04485
uniprot id: A0A0S2HX65
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS08915
gene id: 1307839:L21SP5_RS08915
uniprot id: A0A0S2HZF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1307839:L21SP5 RS05590
gene id: 1307839:L21SP5_RS05590
uniprot id: A0A0S2HXK5
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS18725
gene id: 1307839:L21SP5_RS18725
uniprot id: A0A0S2I4Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1307839:L21SP5 RS12435
gene id: 1307839:L21SP5_RS12435
uniprot id: A0A0S2I1N9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1307839:L21SP5 RS17300
gene id: 1307839:L21SP5_RS17300
uniprot id: A0A0S2I4D9
names: Subcellular Location Annotation
messages: Secreted

1307839:L21SP5 RS07275
gene id: 1307839:L21SP5_RS07275
uniprot id: A0A0S2HYL1
names: Similarity
messages: Belongs to the peptidase S49 family.

1307839:L21SP5 RS04320
gene id: 1307839:L21SP5_RS04320
uniprot id: A0A0S2HWZ0
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS03275
gene id: 1307839:L21SP5_RS03275
uniprot id: A0A0S2I2T4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1307839:L21SP5 RS07160
gene id: 1307839:L21SP5_RS07160
uniprot id: A0A0S2HY96
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

1307839:L21SP5 RS19160
gene id: 1307839:L21SP5_RS19160
uniprot id: A0A0S2I5E2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1307839:L21SP5 RS19370
gene id: 1307839:L21SP5_RS19370
uniprot id: A0A0S2I5G4
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS15580
gene id: 1307839:L21SP5_RS15580
uniprot id: A0A0S2I3F9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1307839:L21SP5 RS10275
gene id: 1307839:L21SP5_RS10275
uniprot id: A0A0S2I0B0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1307839:L21SP5 RS10165
gene id: 1307839:L21SP5_RS10165
uniprot id: A0A0S2I054
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1307839:L21SP5 RS03880
gene id: 1307839:L21SP5_RS03880
uniprot id: A0A0S2HWH7
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1307839:L21SP5 RS07120
gene id: 1307839:L21SP5_RS07120
uniprot id: A0A0S2HYI2
names: Similarity
messages: Belongs to the asparagine synthetase family.

1307839:L21SP5 RS11205
gene id: 1307839:L21SP5_RS11205
uniprot id: A0A0S2I0U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1307839:L21SP5 RS16990
gene id: 1307839:L21SP5_RS16990
uniprot id: A0A0S2I4E8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1307839:L21SP5 RS07490
gene id: 1307839:L21SP5_RS07490
uniprot id: A0A0S2HZ84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1307839:L21SP5 RS08520
gene id: 1307839:L21SP5_RS08520
uniprot id: A0A0S2HZD3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1307839:L21SP5 RS00095
gene id: 1307839:L21SP5_RS00095
uniprot id: A0A0S2HUN4
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1307839:L21SP5 RS08000
gene id: 1307839:L21SP5_RS08000
uniprot id: A0A0S2HZ59
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1307839:L21SP5 RS04380
gene id: 1307839:L21SP5_RS04380
uniprot id: A0A0S2HWY8
names: Similarity
messages: Belongs to the peptidase S51 family.

1307839:L21SP5 RS08335
gene id: 1307839:L21SP5_RS08335
uniprot id: A0A0S2HZG9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1307839:L21SP5 RS01480
gene id: 1307839:L21SP5_RS01480
uniprot id: A0A0S2HVD1
names: Similarity
messages: Belongs to the carbamate kinase family.

1307839:L21SP5 RS09385
gene id: 1307839:L21SP5_RS09385
uniprot id: A0A0S2HZV0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1307839:L21SP5 RS17195
gene id: 1307839:L21SP5_RS17195
uniprot id: A0A0S2I474
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS15110
gene id: 1307839:L21SP5_RS15110
uniprot id: A0A0S2I2Y7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1307839:L21SP5 RS11155
gene id: 1307839:L21SP5_RS11155
uniprot id: A0A0S2I1K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1307839:L21SP5 RS07930
gene id: 1307839:L21SP5_RS07930
uniprot id: A0A0S2HZ50
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1307839:L21SP5 RS16175
gene id: 1307839:L21SP5_RS16175
uniprot id: A0A0S2I3T5
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS18680
gene id: 1307839:L21SP5_RS18680
uniprot id: A0A0S2I565
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1307839:L21SP5 RS09230
gene id: 1307839:L21SP5_RS09230
uniprot id: A0A0S2HZR9
names: Subcellular Location Annotation
messages: Cytoplasm

1307839:L21SP5 RS07910
gene id: 1307839:L21SP5_RS07910
uniprot id: A0A0S2I2T4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1307839:L21SP5 RS14335
gene id: 1307839:L21SP5_RS14335
uniprot id: A0A0S2I2W9
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1307839:L21SP5 RS18070
gene id: 1307839:L21SP5_RS18070
uniprot id: A0A0S2I491
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

1307839:L21SP5 RS00130
gene id: 1307839:L21SP5_RS00130
uniprot id: A0A0S2HUG5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1307839:L21SP5 RS01810
gene id: 1307839:L21SP5_RS01810
uniprot id: A0A0S2HVI9
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1307839:L21SP5 RS11580
gene id: 1307839:L21SP5_RS11580
uniprot id: A0A0S2I117
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1307839:L21SP5 RS11030
gene id: 1307839:L21SP5_RS11030
uniprot id: A0A0S2I0I9
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1307839:L21SP5 RS15200
gene id: 1307839:L21SP5_RS15200
uniprot id: A0A0S2I2Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1307839:L21SP5 RS13170
gene id: 1307839:L21SP5_RS13170
uniprot id: A0A0S2I1Y4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1307839:L21SP5 RS05535
gene id: 1307839:L21SP5_RS05535
uniprot id: A0A0S2HXM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1307839:L21SP5 RS18035
gene id: 1307839:L21SP5_RS18035
uniprot id: A0A0S2I2T4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1307839:L21SP5 RS02320
gene id: 1307839:L21SP5_RS02320
uniprot id: A0A0S2HVQ6
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1307839:L21SP5 RS13270
gene id: 1307839:L21SP5_RS13270
uniprot id: A0A0S2I1Z5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1307839:L21SP5 RS03385
gene id: 1307839:L21SP5_RS03385
uniprot id: A0A0S2HWL0
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1307839:L21SP5 RS11210
gene id: 1307839:L21SP5_RS11210
uniprot id: A0A0S2I0Y3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1307839:L21SP5 RS06390
gene id: 1307839:L21SP5_RS06390
uniprot id: A0A0S2HY40
names: Similarity
messages: Belongs to the asparagine synthetase family.

1307839:L21SP5 RS15175
gene id: 1307839:L21SP5_RS15175
uniprot id: A0A0S2I312
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1307839:L21SP5 RS13220
gene id: 1307839:L21SP5_RS13220
uniprot id: A0A0S2I219
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1307839:L21SP5 RS00255
gene id: 1307839:L21SP5_RS00255
uniprot id: A0A0S2HUS4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS07970
gene id: 1307839:L21SP5_RS07970
uniprot id: A0A0S2HZH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

1307839:L21SP5 RS11425
gene id: 1307839:L21SP5_RS11425
uniprot id: A0A0S2I1D3
names: Similarity
messages: Belongs to the universal stress protein A family.

1307839:L21SP5 RS02020
gene id: 1307839:L21SP5_RS02020
uniprot id: A0A0S2HVL0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1307839:L21SP5 RS18545
gene id: 1307839:L21SP5_RS18545
uniprot id: A0A0S2I541
names: Similarity
messages: Belongs to the acylphosphatase family.

1307839:L21SP5 RS08095
gene id: 1307839:L21SP5_RS08095
uniprot id: A0A0S2HZB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1307839:L21SP5 RS09080
gene id: 1307839:L21SP5_RS09080
uniprot id: A0A0S2I0F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1307839:L21SP5 RS19400
gene id: 1307839:L21SP5_RS19400
uniprot id: A0A0S2I547
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS17385
gene id: 1307839:L21SP5_RS17385
uniprot id: A0A0S2I4A2
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1307839:L21SP5 RS17690
gene id: 1307839:L21SP5_RS17690
uniprot id: A0A0S2I5G3
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS10200
gene id: 1307839:L21SP5_RS10200
uniprot id: A0A0S2I0A4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1307839:L21SP5 RS14315
gene id: 1307839:L21SP5_RS14315
uniprot id: A0A0S2I2I9
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1307839:L21SP5 RS12240
gene id: 1307839:L21SP5_RS12240
uniprot id: A0A0S2I1B2
names: Function
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1307839:L21SP5 RS11100
gene id: 1307839:L21SP5_RS11100
uniprot id: A0A0S2I0S3
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS05180
gene id: 1307839:L21SP5_RS05180
uniprot id: A0A0S2HXG6
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1307839:L21SP5 RS05425
gene id: 1307839:L21SP5_RS05425
uniprot id: A0A0S2HXK3
names: Similarity
messages: Belongs to the peptidase M13 family.

1307839:L21SP5 RS02270
gene id: 1307839:L21SP5_RS02270
uniprot id: A0A0S2HVQ7
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1307839:L21SP5 RS04890
gene id: 1307839:L21SP5_RS04890
uniprot id: A0A0S2HXG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1307839:L21SP5 RS12970
gene id: 1307839:L21SP5_RS12970
uniprot id: A0A0S2I1K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1307839:L21SP5 RS09905
gene id: 1307839:L21SP5_RS09905
uniprot id: A0A0S2I045
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1307839:L21SP5 RS05070
gene id: 1307839:L21SP5_RS05070
uniprot id: A0A0S2HXB1
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1307839:L21SP5 RS11705
gene id: 1307839:L21SP5_RS11705
uniprot id: A0A0S2I181
names: Similarity
messages: Belongs to the UPF0047 family.

1307839:L21SP5 RS19070
gene id: 1307839:L21SP5_RS19070
uniprot id: A0A0S2I5L5
names: Subcellular Location Annotation
messages: Cytoplasm

1307839:L21SP5 RS13295
gene id: 1307839:L21SP5_RS13295
uniprot id: A0A0S2I1P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1307839:L21SP5 RS18370
gene id: 1307839:L21SP5_RS18370
uniprot id: A0A0S2I4Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1307839:L21SP5 RS05460
gene id: 1307839:L21SP5_RS05460
uniprot id: A0A0S2HXE5
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1307839:L21SP5 RS18740
gene id: 1307839:L21SP5_RS18740
uniprot id: A0A0S2I4T8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1307839:L21SP5 RS04375
gene id: 1307839:L21SP5_RS04375
uniprot id: A0A0S2HWY4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

1307839:L21SP5 RS14530
gene id: 1307839:L21SP5_RS14530
uniprot id: A0A0S2I3L5
names: Similarity
messages: Belongs to the Skp family.

1307839:L21SP5 RS02785
gene id: 1307839:L21SP5_RS02785
uniprot id: A0A0S2HWE2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1307839:L21SP5 RS11080
gene id: 1307839:L21SP5_RS11080
uniprot id: A0A0S2I0S7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1307839:L21SP5 RS19035
gene id: 1307839:L21SP5_RS19035
uniprot id: A0A0S2I5B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1307839:L21SP5 RS09720
gene id: 1307839:L21SP5_RS09720
uniprot id: A0A0S2I013
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1307839:L21SP5 RS16015
gene id: 1307839:L21SP5_RS16015
uniprot id: A0A0S2I3E9
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS13025
gene id: 1307839:L21SP5_RS13025
uniprot id: A0A0S2I1V3
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS04615
gene id: 1307839:L21SP5_RS04615
uniprot id: A0A0S2HXS3
names: Similarity
messages: Belongs to the CIA30 family.

1307839:L21SP5 RS19200
gene id: 1307839:L21SP5_RS19200
uniprot id: A0A0S2I5B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1307839:L21SP5 RS10110
gene id: 1307839:L21SP5_RS10110
uniprot id: A0A0S2I035
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1307839:L21SP5 RS05170
gene id: 1307839:L21SP5_RS05170
uniprot id: A0A0S2HX93
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1307839:L21SP5 RS11975
gene id: 1307839:L21SP5_RS11975
uniprot id: A0A0S2I1Y9
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1307839:L21SP5 RS06110
gene id: 1307839:L21SP5_RS06110
uniprot id: A0A0S2HXY8
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.
messages: Belongs to the radical SAM superfamily. NifB family.

1307839:L21SP5 RS17520
gene id: 1307839:L21SP5_RS17520
uniprot id: A0A0S2I5D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1307839:L21SP5 RS11935
gene id: 1307839:L21SP5_RS11935
uniprot id: A0A0S2I1L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1307839:L21SP5 RS12360
gene id: 1307839:L21SP5_RS12360
uniprot id: A0A0S2I182
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1307839:L21SP5 RS04675
gene id: 1307839:L21SP5_RS04675
uniprot id: A0A0S2HX48
names: Subcellular Location Annotation
messages: Membrane

1307839:L21SP5 RS17335
gene id: 1307839:L21SP5_RS17335
uniprot id: A0A0S2I457
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1307839:L21SP5 RS13535
gene id: 1307839:L21SP5_RS13535
uniprot id: A0A0S2I284
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1307839:L21SP5 RS19395
gene id: 1307839:L21SP5_RS19395
uniprot id: A0A0S2I5I1
names: Similarity
messages: Belongs to the CinA family.

1307839:L21SP5 RS11835
gene id: 1307839:L21SP5_RS11835
uniprot id: A0A0S2I132
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1307839:L21SP5 RS09640
gene id: 1307839:L21SP5_RS09640
uniprot id: A0A0S2HZZ3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1307839:L21SP5 RS15070
gene id: 1307839:L21SP5_RS15070
uniprot id: A0A0S2I2M0
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1307839:L21SP5 RS05840
gene id: 1307839:L21SP5_RS05840
uniprot id: A0A0S2HXQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1307839:L21SP5 RS01860
gene id: 1307839:L21SP5_RS01860
uniprot id: A0A0S2HVI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1307839:L21SP5 RS17860
gene id: 1307839:L21SP5_RS17860
uniprot id: A0A0S2I4I9
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1307839:L21SP5 RS09910
gene id: 1307839:L21SP5_RS09910
uniprot id: A0A0S2I058
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1307839:L21SP5 RS08325
gene id: 1307839:L21SP5_RS08325
uniprot id: A0A0S2HZ10
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.