1302659:I858 RS13225
gene id: 1302659:I858_RS13225
uniprot id: A0A1B1S2T3
names: Similarity
messages: Belongs to the peptidase C40 family.

1302659:I858 RS08930
gene id: 1302659:I858_RS08930
uniprot id: A0A1B1S566
names: Similarity
messages: Belongs to the Fur family.

1302659:I858 RS16545
gene id: 1302659:I858_RS16545
uniprot id: A0A1B1S5Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1302659:I858 RS09365
gene id: 1302659:I858_RS09365
uniprot id: A0A1B1S4Y2
names: Subcellular Location Annotation
messages: Cytoplasm

1302659:I858 RS04660
gene id: 1302659:I858_RS04660
uniprot id: A0A1B1RYP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1302659:I858 RS16275
gene id: 1302659:I858_RS16275
uniprot id: A0A1B1S179
names: Similarity
messages: Belongs to the ParB family.

1302659:I858 RS13975
gene id: 1302659:I858_RS13975
uniprot id: A0A1B1S2G5
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Consists of two distinct domains; an N-terminal heme-containing oxygen-binding domain and a C-terminal reductase domain with binding sites for FAD and NAD(P)H.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS06145
gene id: 1302659:I858_RS06145
uniprot id: A0A1B1RXZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS13730
gene id: 1302659:I858_RS13730
uniprot id: A0A1B1S2I4
names: Caution
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1302659:I858 RS14955
gene id: 1302659:I858_RS14955
uniprot id: A0A1B1S1X9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1302659:I858 RS13195
gene id: 1302659:I858_RS13195
uniprot id: A0A1B1S2T9
names: Similarity
messages: Belongs to the EamA transporter family.

1302659:I858 RS13110
gene id: 1302659:I858_RS13110
uniprot id: A0A1B1S2V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS10460
gene id: 1302659:I858_RS10460
uniprot id: A0A1B1S4B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS10725
gene id: 1302659:I858_RS10725
uniprot id: A0A1B1S4B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1302659:I858 RS10850
gene id: 1302659:I858_RS10850
uniprot id: A0A1B1S449
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1302659:I858 RS10350
gene id: 1302659:I858_RS10350
uniprot id: A0A1B1S4E2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1302659:I858 RS12515
gene id: 1302659:I858_RS12515
uniprot id: A0A1B1S366
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1302659:I858 RS00780
gene id: 1302659:I858_RS00780
uniprot id: A0A1B1S0Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

1302659:I858 RS14445
gene id: 1302659:I858_RS14445
uniprot id: A0A1B1S239
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1302659:I858 RS07145
gene id: 1302659:I858_RS07145
uniprot id: A0A1B1RXD8
names: Similarity
messages: Belongs to the UPF0297 family.

1302659:I858 RS00140
gene id: 1302659:I858_RS00140
uniprot id: A0A1B1S112
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1302659:I858 RS03865
gene id: 1302659:I858_RS03865
uniprot id: A0A1B1RZ40
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1302659:I858 RS15110
gene id: 1302659:I858_RS15110
uniprot id: A0A1B1S1U9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1302659:I858 RS07730
gene id: 1302659:I858_RS07730
uniprot id: A0A1B1RX24
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1302659:I858 RS15530
gene id: 1302659:I858_RS15530
uniprot id: A0A1B1S1H2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1302659:I858 RS04070
gene id: 1302659:I858_RS04070
uniprot id: A0A1B1RYW0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1302659:I858 RS15965
gene id: 1302659:I858_RS15965
uniprot id: A0A1B1S186
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS11865
gene id: 1302659:I858_RS11865
uniprot id: A0A1B1S3J0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1302659:I858 RS04605
gene id: 1302659:I858_RS04605
uniprot id: A0A1B1RYK4
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1302659:I858 RS04750
gene id: 1302659:I858_RS04750
uniprot id: A0A1B1RYL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS09355
gene id: 1302659:I858_RS09355
uniprot id: A0A1B1S4Y8
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS13070
gene id: 1302659:I858_RS13070
uniprot id: A0A1B1S2W4
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS11130
gene id: 1302659:I858_RS11130
uniprot id: A0A1B1S3Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

1302659:I858 RS01825
gene id: 1302659:I858_RS01825
uniprot id: A0A1B1S071
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1302659:I858 RS01080
gene id: 1302659:I858_RS01080
uniprot id: A0A1B1S0N2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1302659:I858 RS09410
gene id: 1302659:I858_RS09410
uniprot id: A0A1B1S4V7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

1302659:I858 RS00590
gene id: 1302659:I858_RS00590
uniprot id: A0A1B1S0U2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1302659:I858 RS03670
gene id: 1302659:I858_RS03670
uniprot id: A0A1B1RZ68
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1302659:I858 RS04425
gene id: 1302659:I858_RS04425
uniprot id: A0A1B1RYR9
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1302659:I858 RS12450
gene id: 1302659:I858_RS12450
uniprot id: A0A1B1S387
names: Similarity
messages: Belongs to the threonine aldolase family.

1302659:I858 RS06045
gene id: 1302659:I858_RS06045
uniprot id: A0A1B1RY18
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1302659:I858 RS07310
gene id: 1302659:I858_RS07310
uniprot id: A0A1B1RXA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1302659:I858 RS05415
gene id: 1302659:I858_RS05415
uniprot id: A0A1B1RY84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1302659:I858 RS13780
gene id: 1302659:I858_RS13780
uniprot id: A0A1B1S2H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1302659:I858 RS11090
gene id: 1302659:I858_RS11090
uniprot id: A0A1B1S402
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1302659:I858 RS12155
gene id: 1302659:I858_RS12155
uniprot id: A0A1B1S3D3
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1302659:I858 RS01285
gene id: 1302659:I858_RS01285
uniprot id: A0A1B1S0G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1302659:I858 RS00535
gene id: 1302659:I858_RS00535
uniprot id: A0A1B1S0U9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1302659:I858 RS13670
gene id: 1302659:I858_RS13670
uniprot id: A0A1B1S2J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS12920
gene id: 1302659:I858_RS12920
uniprot id: A0A1B1S2Y9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1302659:I858 RS11775
gene id: 1302659:I858_RS11775
uniprot id: A0A1B1S3M3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1302659:I858 RS01615
gene id: 1302659:I858_RS01615
uniprot id: A0A1B1S0B0
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1302659:I858 RS15170
gene id: 1302659:I858_RS15170
uniprot id: A0A1B1S1P6
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS09050
gene id: 1302659:I858_RS09050
uniprot id: A0A1B1S546
names: Similarity
messages: Belongs to the PemK/MazF family.

1302659:I858 RS07050
gene id: 1302659:I858_RS07050
uniprot id: A0A1B1RXF8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1302659:I858 RS14200
gene id: 1302659:I858_RS14200
uniprot id: A0A1B1S290
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1302659:I858 RS10550
gene id: 1302659:I858_RS10550
uniprot id: A0A1B1S4B0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1302659:I858 RS01775
gene id: 1302659:I858_RS01775
uniprot id: A0A1B1S082
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1302659:I858 RS05505
gene id: 1302659:I858_RS05505
uniprot id: A0A1B1RY74
names: Similarity
messages: Belongs to the ArsC family.

1302659:I858 RS08135
gene id: 1302659:I858_RS08135
uniprot id: A0A1B1S5M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family. ParE type 2 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1302659:I858 RS04435
gene id: 1302659:I858_RS04435
uniprot id: A0A1B1RYS1
names: Similarity
messages: Belongs to the GARS family.

1302659:I858 RS10890
gene id: 1302659:I858_RS10890
uniprot id: A0A1B1S411
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1302659:I858 RS00445
gene id: 1302659:I858_RS00445
uniprot id: A0A1B1S0U6
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1302659:I858 RS07065
gene id: 1302659:I858_RS07065
uniprot id: A0A1B1RXF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1302659:I858 RS11045
gene id: 1302659:I858_RS11045
uniprot id: A0A1B1S3Y0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

1302659:I858 RS13440
gene id: 1302659:I858_RS13440
uniprot id: A0A1B1S2P7
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

1302659:I858 RS00530
gene id: 1302659:I858_RS00530
uniprot id: A0A1B1S0W3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1302659:I858 RS08660
gene id: 1302659:I858_RS08660
uniprot id: A0A1B1S5C6
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1302659:I858 RS02495
gene id: 1302659:I858_RS02495
uniprot id: A0A1B1RZU4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1302659:I858 RS02010
gene id: 1302659:I858_RS02010
uniprot id: A0A1B1S045
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1302659:I858 RS06520
gene id: 1302659:I858_RS06520
uniprot id: A0A1B1RXQ8
names: Similarity
messages: Belongs to the citrate synthase family.

1302659:I858 RS16310
gene id: 1302659:I858_RS16310
uniprot id: A0A1B1S145
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

1302659:I858 RS01930
gene id: 1302659:I858_RS01930
uniprot id: A0A1B1S053
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1302659:I858 RS10620
gene id: 1302659:I858_RS10620
uniprot id: A0A1B1S476
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS13495
gene id: 1302659:I858_RS13495
uniprot id: A0A1B1S2N1
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1302659:I858 RS15050
gene id: 1302659:I858_RS15050
uniprot id: A0A1B1S1S4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1302659:I858 RS13520
gene id: 1302659:I858_RS13520
uniprot id: A0A1B1S2M6
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1302659:I858 RS11535
gene id: 1302659:I858_RS11535
uniprot id: A0A1B1S3U9
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

1302659:I858 RS07125
gene id: 1302659:I858_RS07125
uniprot id: A0A1B1RXE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

1302659:I858 RS08695
gene id: 1302659:I858_RS08695
uniprot id: A0A1B1S5A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1302659:I858 RS10780
gene id: 1302659:I858_RS10780
uniprot id: A0A1B1S458
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1302659:I858 RS00105
gene id: 1302659:I858_RS00105
uniprot id: A0A1B1S129
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1302659:I858 RS13915
gene id: 1302659:I858_RS13915
uniprot id: A0A1B1S2E7
names: Subcellular Location Annotation
messages: Cell membrane

1302659:I858 RS01895
gene id: 1302659:I858_RS01895
uniprot id: A0A1B1S044
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1302659:I858 RS15185
gene id: 1302659:I858_RS15185
uniprot id: A0A1B1S1S7
names: Similarity
messages: Belongs to the Gfa family.

1302659:I858 RS07855
gene id: 1302659:I858_RS07855
uniprot id: A0A1B1S5S2
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

1302659:I858 RS00905
gene id: 1302659:I858_RS00905
uniprot id: A0A1B1S0L5
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1302659:I858 RS05465
gene id: 1302659:I858_RS05465
uniprot id: A0A1B1RY93
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS14135
gene id: 1302659:I858_RS14135
uniprot id: A0A1B1S295
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1302659:I858 RS03910
gene id: 1302659:I858_RS03910
uniprot id: A0A1B1RZ16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS16070
gene id: 1302659:I858_RS16070
uniprot id: A0A1B1S167
names: Similarity
messages: Belongs to the MQO family.

1302659:I858 RS06685
gene id: 1302659:I858_RS06685
uniprot id: A0A1B1RXM7
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS10210
gene id: 1302659:I858_RS10210
uniprot id: A0A1B1S4G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Involved in the degradation of specific anti-sigma factors.
messages: Membrane

1302659:I858 RS11975
gene id: 1302659:I858_RS11975
uniprot id: A0A1B1S3G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1302659:I858 RS14070
gene id: 1302659:I858_RS14070
uniprot id: A0A1B1S2B1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1302659:I858 RS02820
gene id: 1302659:I858_RS02820
uniprot id: A0A1B1RZM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS13415
gene id: 1302659:I858_RS13415
uniprot id: A0A1B1S2S6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS07325
gene id: 1302659:I858_RS07325
uniprot id: A0A1B1RX98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

1302659:I858 RS00060
gene id: 1302659:I858_RS00060
uniprot id: A0A1B1S119
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1302659:I858 RS10130
gene id: 1302659:I858_RS10130
uniprot id: A0A1B1S4G6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1302659:I858 RS10875
gene id: 1302659:I858_RS10875
uniprot id: A0A1B1S430
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1302659:I858 RS13420
gene id: 1302659:I858_RS13420
uniprot id: A0A1B1S2P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1302659:I858 RS07760
gene id: 1302659:I858_RS07760
uniprot id: A0A1B1RX18
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1302659:I858 RS00720
gene id: 1302659:I858_RS00720
uniprot id: A0A1B1S0T5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1302659:I858 RS11140
gene id: 1302659:I858_RS11140
uniprot id: A0A1B1S3Y8
names: Similarity
messages: Belongs to the UPF0749 family.

1302659:I858 RS11295
gene id: 1302659:I858_RS11295
uniprot id: A0A1B1S3S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Membrane

1302659:I858 RS02220
gene id: 1302659:I858_RS02220
uniprot id: A0A1B1S001
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1302659:I858 RS07350
gene id: 1302659:I858_RS07350
uniprot id: A0A1B1RXA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

1302659:I858 RS02580
gene id: 1302659:I858_RS02580
uniprot id: A0A1B1RZN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1302659:I858 RS11420
gene id: 1302659:I858_RS11420
uniprot id: A0A1B1S3U2
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1302659:I858 RS10335
gene id: 1302659:I858_RS10335
uniprot id: A0A1B1S4D8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1302659:I858 RS02395
gene id: 1302659:I858_RS02395
uniprot id: A0A1B1RZW1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1302659:I858 RS15190
gene id: 1302659:I858_RS15190
uniprot id: A0A1B1S1Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS10720
gene id: 1302659:I858_RS10720
uniprot id: A0A1B1S456
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1302659:I858 RS04340
gene id: 1302659:I858_RS04340
uniprot id: A0A1B1RYU6
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1302659:I858 RS15120
gene id: 1302659:I858_RS15120
uniprot id: A0A1B1S1Q3
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1302659:I858 RS11430
gene id: 1302659:I858_RS11430
uniprot id: A0A1B1S3S9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1302659:I858 RS13030
gene id: 1302659:I858_RS13030
uniprot id: A0A1B1S2X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LytR/CpsA/Psr (LCP) family.
messages: Cell membrane
messages: May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG).

1302659:I858 RS00475
gene id: 1302659:I858_RS00475
uniprot id: A0A1B1S0X4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1302659:I858 RS13800
gene id: 1302659:I858_RS13800
uniprot id: A0A1B1S2H7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

1302659:I858 RS02655
gene id: 1302659:I858_RS02655
uniprot id: A0A1B1RZP0
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).

1302659:I858 RS16435
gene id: 1302659:I858_RS16435
uniprot id: A0A1B1S5U3
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS02465
gene id: 1302659:I858_RS02465
uniprot id: A0A1B1RZT4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1302659:I858 RS08185
gene id: 1302659:I858_RS08185
uniprot id: A0A1B1S5L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1302659:I858 RS01005
gene id: 1302659:I858_RS01005
uniprot id: A0A1B1S0Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1302659:I858 RS02570
gene id: 1302659:I858_RS02570
uniprot id: A0A1B1RZS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS06320
gene id: 1302659:I858_RS06320
uniprot id: A0A1B1RXU4
names: Similarity
messages: Belongs to the histone deacetylase family.

1302659:I858 RS03495
gene id: 1302659:I858_RS03495
uniprot id: A0A1B1RZ94
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS02940
gene id: 1302659:I858_RS02940
uniprot id: A0A1B1RZL6
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS08720
gene id: 1302659:I858_RS08720
uniprot id: A0A1B1S5D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1302659:I858 RS14195
gene id: 1302659:I858_RS14195
uniprot id: A0A1B1S286
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1302659:I858 RS12780
gene id: 1302659:I858_RS12780
uniprot id: A0A1B1S315
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

1302659:I858 RS09465
gene id: 1302659:I858_RS09465
uniprot id: A0A1B1S4W3
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1302659:I858 RS15985
gene id: 1302659:I858_RS15985
uniprot id: A0A1B1S1C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1302659:I858 RS05335
gene id: 1302659:I858_RS05335
uniprot id: A0A1B1RYC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1302659:I858 RS10055
gene id: 1302659:I858_RS10055
uniprot id: A0A1B1S4J7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1302659:I858 RS14715
gene id: 1302659:I858_RS14715
uniprot id: A0A1B1S1Z0
names: Subcellular Location Annotation
messages: Cell membrane

1302659:I858 RS13170
gene id: 1302659:I858_RS13170
uniprot id: A0A1B1S2T1
names: Similarity
messages: Belongs to the peptidase C40 family.

1302659:I858 RS10755
gene id: 1302659:I858_RS10755
uniprot id: A0A1B1S460
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1302659:I858 RS02390
gene id: 1302659:I858_RS02390
uniprot id: A0A1B1RZW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1302659:I858 RS02065
gene id: 1302659:I858_RS02065
uniprot id: A0A1B1S035
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1302659:I858 RS16640
gene id: 1302659:I858_RS16640
uniprot id: A0A1B1S5Y6
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS01040
gene id: 1302659:I858_RS01040
uniprot id: A0A1B1S0M2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1302659:I858 RS11215
gene id: 1302659:I858_RS11215
uniprot id: A0A1B1S3X1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1302659:I858 RS04985
gene id: 1302659:I858_RS04985
uniprot id: A0A1B1RYJ3
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1302659:I858 RS09975
gene id: 1302659:I858_RS09975
uniprot id: A0A1B1S4L4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.

1302659:I858 RS08760
gene id: 1302659:I858_RS08760
uniprot id: A0A1B1S592
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1302659:I858 RS06900
gene id: 1302659:I858_RS06900
uniprot id: A0A1B1RXJ2
names: Similarity
messages: Belongs to the GSP E family.

1302659:I858 RS06205
gene id: 1302659:I858_RS06205
uniprot id: A0A1B1RXY6
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS05115
gene id: 1302659:I858_RS05115
uniprot id: A0A1B1RYG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

1302659:I858 RS02005
gene id: 1302659:I858_RS02005
uniprot id: A0A1B1S029
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1302659:I858 RS00795
gene id: 1302659:I858_RS00795
uniprot id: A0A1B1S0P6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1302659:I858 RS14635
gene id: 1302659:I858_RS14635
uniprot id: A0A1B1S209
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1302659:I858 RS03555
gene id: 1302659:I858_RS03555
uniprot id: A0A1B1RZA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS01940
gene id: 1302659:I858_RS01940
uniprot id: A0A1B1S030
names: Similarity
messages: Belongs to the UPF0178 family.

1302659:I858 RS14110
gene id: 1302659:I858_RS14110
uniprot id: A0A1B1S2B3
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1302659:I858 RS12835
gene id: 1302659:I858_RS12835
uniprot id: A0A1B1S306
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1302659:I858 RS08730
gene id: 1302659:I858_RS08730
uniprot id: A0A1B1S5A1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1302659:I858 RS10180
gene id: 1302659:I858_RS10180
uniprot id: A0A1B1S4F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1302659:I858 RS00465
gene id: 1302659:I858_RS00465
uniprot id: A0A1B1S0Y6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS00300
gene id: 1302659:I858_RS00300
uniprot id: A0A1B1S0Y0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1302659:I858 RS03040
gene id: 1302659:I858_RS03040
uniprot id: A0A1B1RZI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS05385
gene id: 1302659:I858_RS05385
uniprot id: A0A1B1RYA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1302659:I858 RS02615
gene id: 1302659:I858_RS02615
uniprot id: A0A1B1RZQ4
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1302659:I858 RS09325
gene id: 1302659:I858_RS09325
uniprot id: A0A1B1S508
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1302659:I858 RS06160
gene id: 1302659:I858_RS06160
uniprot id: A0A1B1RXX0
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1302659:I858 RS15680
gene id: 1302659:I858_RS15680
uniprot id: A0A1B1S1G3
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1302659:I858 RS13300
gene id: 1302659:I858_RS13300
uniprot id: A0A1B1S2R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1302659:I858 RS14270
gene id: 1302659:I858_RS14270
uniprot id: A0A1B1S277
names: Similarity
messages: Belongs to the class-I fumarase family.

1302659:I858 RS01110
gene id: 1302659:I858_RS01110
uniprot id: A0A1B1S0H6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1302659:I858 RS10100
gene id: 1302659:I858_RS10100
uniprot id: A0A1B1S4J2
names: Similarity
messages: Belongs to the UPF0302 family.

1302659:I858 RS03370
gene id: 1302659:I858_RS03370
uniprot id: A0A1B1RZD0
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1302659:I858 RS07925
gene id: 1302659:I858_RS07925
uniprot id: A0A1B1S5R0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

1302659:I858 RS15865
gene id: 1302659:I858_RS15865
uniprot id: A0A1B1S1B2
names: Similarity
messages: Belongs to the EamA transporter family.

1302659:I858 RS11745
gene id: 1302659:I858_RS11745
uniprot id: A0A1B1S3L4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS06915
gene id: 1302659:I858_RS06915
uniprot id: A0A1B1RXH7
names: Function
messages: Required for transformation and DNA binding.

1302659:I858 RS16025
gene id: 1302659:I858_RS16025
uniprot id: A0A1B1S181
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1302659:I858 RS05430
gene id: 1302659:I858_RS05430
uniprot id: A0A1B1RY82
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1302659:I858 RS11485
gene id: 1302659:I858_RS11485
uniprot id: A0A1B1S3V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS09495
gene id: 1302659:I858_RS09495
uniprot id: A0A1B1S4U2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS05900
gene id: 1302659:I858_RS05900
uniprot id: A0A1B1RY19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1302659:I858 RS11080
gene id: 1302659:I858_RS11080
uniprot id: A0A1B1S3Z2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1302659:I858 RS12455
gene id: 1302659:I858_RS12455
uniprot id: A0A1B1S381
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1302659:I858 RS06565
gene id: 1302659:I858_RS06565
uniprot id: A0A1B1RXQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1302659:I858 RS14165
gene id: 1302659:I858_RS14165
uniprot id: A0A1B1S299
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1302659:I858 RS16625
gene id: 1302659:I858_RS16625
uniprot id: A0A1B1S5Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1302659:I858 RS10895
gene id: 1302659:I858_RS10895
uniprot id: A0A1B1S426
names: Function
names: Similarity
messages: Belongs to the FapR family.
messages: Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism.

1302659:I858 RS04610
gene id: 1302659:I858_RS04610
uniprot id: A0A1B1RYQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1302659:I858 RS02110
gene id: 1302659:I858_RS02110
uniprot id: A0A1B1S010
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Cytoplasm

1302659:I858 RS04345
gene id: 1302659:I858_RS04345
uniprot id: A0A1B1RYU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1302659:I858 RS12250
gene id: 1302659:I858_RS12250
uniprot id: A0A1B1S3C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS16110
gene id: 1302659:I858_RS16110
uniprot id: A0A1B1S178
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS14430
gene id: 1302659:I858_RS14430
uniprot id: A0A1B1S281
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS10330
gene id: 1302659:I858_RS10330
uniprot id: A0A1B1S4C5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

1302659:I858 RS08705
gene id: 1302659:I858_RS08705
uniprot id: A0A1B1S5A2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1302659:I858 RS03505
gene id: 1302659:I858_RS03505
uniprot id: A0A1B1RZB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1302659:I858 RS08910
gene id: 1302659:I858_RS08910
uniprot id: A0A1B1S565
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1302659:I858 RS00470
gene id: 1302659:I858_RS00470
uniprot id: A0A1B1S0W6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1302659:I858 RS05560
gene id: 1302659:I858_RS05560
uniprot id: A0A1B1RY83
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1302659:I858 RS00560
gene id: 1302659:I858_RS00560
uniprot id: A0A1B1S0V6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1302659:I858 RS12550
gene id: 1302659:I858_RS12550
uniprot id: A0A1B1S368
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

1302659:I858 RS04615
gene id: 1302659:I858_RS04615
uniprot id: A0A1B1RYP4
names: Similarity
messages: Belongs to the peptidase M29 family.

1302659:I858 RS07270
gene id: 1302659:I858_RS07270
uniprot id: A0A1B1RXB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1302659:I858 RS07030
gene id: 1302659:I858_RS07030
uniprot id: A0A1B1RXG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1302659:I858 RS10870
gene id: 1302659:I858_RS10870
uniprot id: A0A1B1S427
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1302659:I858 RS11015
gene id: 1302659:I858_RS11015
uniprot id: A0A1B1S413
names: Similarity
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.

1302659:I858 RS14605
gene id: 1302659:I858_RS14605
uniprot id: A0A1B1S210
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1302659:I858 RS02430
gene id: 1302659:I858_RS02430
uniprot id: A0A1B1RZS1
names: Similarity
messages: Belongs to the CvfB family.

1302659:I858 RS07600
gene id: 1302659:I858_RS07600
uniprot id: A0A1B1RX55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1302659:I858 RS08620
gene id: 1302659:I858_RS08620
uniprot id: A0A1B1S5F0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1302659:I858 RS10810
gene id: 1302659:I858_RS10810
uniprot id: A0A1B1S455
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1302659:I858 RS13260
gene id: 1302659:I858_RS13260
uniprot id: A0A1B1S2S7
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS11190
gene id: 1302659:I858_RS11190
uniprot id: A0A1B1S3X8
names: Similarity
messages: Belongs to the ketopantoate reductase family.

1302659:I858 RS10910
gene id: 1302659:I858_RS10910
uniprot id: A0A1B1S432
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1302659:I858 RS14520
gene id: 1302659:I858_RS14520
uniprot id: A0A1B1S230
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1302659:I858 RS01910
gene id: 1302659:I858_RS01910
uniprot id: A0A1B1S066
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1302659:I858 RS10970
gene id: 1302659:I858_RS10970
uniprot id: A0A1B1S409
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1302659:I858 RS05255
gene id: 1302659:I858_RS05255
uniprot id: A0A1B1RYC9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1302659:I858 RS03665
gene id: 1302659:I858_RS03665
uniprot id: A0A1B1RZ81
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS08035
gene id: 1302659:I858_RS08035
uniprot id: A0A1B1S5P8
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1302659:I858 RS13530
gene id: 1302659:I858_RS13530
uniprot id: A0A1B1S2M4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1302659:I858 RS11730
gene id: 1302659:I858_RS11730
uniprot id: A0A1B1S3L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1302659:I858 RS13885
gene id: 1302659:I858_RS13885
uniprot id: A0A1B1S2E4
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1302659:I858 RS05400
gene id: 1302659:I858_RS05400
uniprot id: A0A1B1RYB9
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1302659:I858 RS04445
gene id: 1302659:I858_RS04445
uniprot id: A0A1B1RYS4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1302659:I858 RS13700
gene id: 1302659:I858_RS13700
uniprot id: A0A1B1S2J6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1302659:I858 RS04515
gene id: 1302659:I858_RS04515
uniprot id: A0A1B1RYR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1302659:I858 RS09755
gene id: 1302659:I858_RS09755
uniprot id: A0A1B1S4U8
names: Function
names: Similarity
names: Subunit
messages: In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.
messages: Monomer.
messages: Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine.

1302659:I858 RS01010
gene id: 1302659:I858_RS01010
uniprot id: A0A1B1S0J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1302659:I858 RS00245
gene id: 1302659:I858_RS00245
uniprot id: A0A1B1S123
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1302659:I858 RS11620
gene id: 1302659:I858_RS11620
uniprot id: A0A1B1S3Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1302659:I858 RS06820
gene id: 1302659:I858_RS06820
uniprot id: A0A1B1RXK4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1302659:I858 RS14750
gene id: 1302659:I858_RS14750
uniprot id: A0A1B1S219
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1302659:I858 RS14025
gene id: 1302659:I858_RS14025
uniprot id: A0A1B1S2F6
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

1302659:I858 RS05175
gene id: 1302659:I858_RS05175
uniprot id: A0A1B1RYF8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS04655
gene id: 1302659:I858_RS04655
uniprot id: A0A1B1RYJ7
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS06580
gene id: 1302659:I858_RS06580
uniprot id: A0A1B1RXP3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1302659:I858 RS11630
gene id: 1302659:I858_RS11630
uniprot id: A0A1B1S3N8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1302659:I858 RS15765
gene id: 1302659:I858_RS15765
uniprot id: A0A1B1S1D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1302659:I858 RS03800
gene id: 1302659:I858_RS03800
uniprot id: A0A1B1RZ38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS06430
gene id: 1302659:I858_RS06430
uniprot id: A0A1B1RXS7
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS11770
gene id: 1302659:I858_RS11770
uniprot id: A0A1B1S3L3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adapter protein required for efficient degradation of Spx by ClpXP under non-stress conditions. Interaction with Spx stabilizes Spx and exposes the C-terminus of Spx for recognition and proteolysis by ClpXP.
messages: Belongs to the SpxH family.
messages: Cytoplasm
messages: Interacts with Spx.

1302659:I858 RS05285
gene id: 1302659:I858_RS05285
uniprot id: A0A1B1RYD1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1302659:I858 RS05695
gene id: 1302659:I858_RS05695
uniprot id: A0A1B1RY65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS13605
gene id: 1302659:I858_RS13605
uniprot id: A0A1B1S2K9
names: Similarity
messages: Belongs to the ChdC family. Type 1 subfamily.

1302659:I858 RS10310
gene id: 1302659:I858_RS10310
uniprot id: A0A1B1S4E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

1302659:I858 RS14930
gene id: 1302659:I858_RS14930
uniprot id: A0A1B1S1X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1302659:I858 RS05370
gene id: 1302659:I858_RS05370
uniprot id: A0A1B1RYC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1302659:I858 RS10255
gene id: 1302659:I858_RS10255
uniprot id: A0A1B1S4G0
names: Similarity
messages: Belongs to the peptidase S8 family.

1302659:I858 RS12220
gene id: 1302659:I858_RS12220
uniprot id: A0A1B1S3C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS14545
gene id: 1302659:I858_RS14545
uniprot id: A0A1B1S221
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1302659:I858 RS13010
gene id: 1302659:I858_RS13010
uniprot id: A0A1B1S2V7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1302659:I858 RS07245
gene id: 1302659:I858_RS07245
uniprot id: A0A1B1RXC0
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1302659:I858 RS11785
gene id: 1302659:I858_RS11785
uniprot id: A0A1B1S3L2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MecA family.
messages: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
messages: Homodimer.
messages: The N-terminal domain probably binds unfolded/aggregated proteins; the C-terminal domain interacts with ClpC.

1302659:I858 RS05530
gene id: 1302659:I858_RS05530
uniprot id: A0A1B1RY76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS02785
gene id: 1302659:I858_RS02785
uniprot id: A0A1B1RZP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1302659:I858 RS00605
gene id: 1302659:I858_RS00605
uniprot id: A0A1B1S0R8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1302659:I858 RS07280
gene id: 1302659:I858_RS07280
uniprot id: A0A1B1RXB1
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1302659:I858 RS06955
gene id: 1302659:I858_RS06955
uniprot id: A0A1B1RXH6
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1302659:I858 RS13395
gene id: 1302659:I858_RS13395
uniprot id: A0A1B1S2Q0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1302659:I858 RS04470
gene id: 1302659:I858_RS04470
uniprot id: A0A1B1RYQ4
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1302659:I858 RS14495
gene id: 1302659:I858_RS14495
uniprot id: A0A1B1S223
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1302659:I858 RS02900
gene id: 1302659:I858_RS02900
uniprot id: A0A1B1RZM8
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS08085
gene id: 1302659:I858_RS08085
uniprot id: A0A1B1S5L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1302659:I858 RS05920
gene id: 1302659:I858_RS05920
uniprot id: A0A1B1RY36
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS07580
gene id: 1302659:I858_RS07580
uniprot id: A0A1B1RX53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS10025
gene id: 1302659:I858_RS10025
uniprot id: A0A1B1S4K3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1302659:I858 RS14380
gene id: 1302659:I858_RS14380
uniprot id: A0A1B1S291
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1302659:I858 RS13540
gene id: 1302659:I858_RS13540
uniprot id: A0A1B1S2M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1302659:I858 RS06365
gene id: 1302659:I858_RS06365
uniprot id: A0A1B1RXU9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily.

1302659:I858 RS00705
gene id: 1302659:I858_RS00705
uniprot id: A0A1B1S0P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1302659:I858 RS02295
gene id: 1302659:I858_RS02295
uniprot id: A0A1B1RZX8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1302659:I858 RS07360
gene id: 1302659:I858_RS07360
uniprot id: A0A1B1RX96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1302659:I858 RS16195
gene id: 1302659:I858_RS16195
uniprot id: A0A1B1S187
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS06755
gene id: 1302659:I858_RS06755
uniprot id: A0A1B1RXM1
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1302659:I858 RS10815
gene id: 1302659:I858_RS10815
uniprot id: A0A1B1S440
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1302659:I858 RS13335
gene id: 1302659:I858_RS13335
uniprot id: A0A1B1S2R3
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS01315
gene id: 1302659:I858_RS01315
uniprot id: A0A1B1S0H7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1302659:I858 RS10065
gene id: 1302659:I858_RS10065
uniprot id: A0A1B1S4I5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1302659:I858 RS15220
gene id: 1302659:I858_RS15220
uniprot id: A0A1B1S1N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

1302659:I858 RS01810
gene id: 1302659:I858_RS01810
uniprot id: A0A1B1S087
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1302659:I858 RS00920
gene id: 1302659:I858_RS00920
uniprot id: A0A1B1S0Q3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1302659:I858 RS01480
gene id: 1302659:I858_RS01480
uniprot id: A0A1B1S0F2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1302659:I858 RS00870
gene id: 1302659:I858_RS00870
uniprot id: A0A1B1S0R4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1302659:I858 RS14085
gene id: 1302659:I858_RS14085
uniprot id: A0A1B1S2A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS10125
gene id: 1302659:I858_RS10125
uniprot id: A0A1B1S4I3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS05690
gene id: 1302659:I858_RS05690
uniprot id: A0A1B1RY42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Membrane

1302659:I858 RS06570
gene id: 1302659:I858_RS06570
uniprot id: A0A1B1RXQ0
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Monomer.

1302659:I858 RS06945
gene id: 1302659:I858_RS06945
uniprot id: A0A1B1RXI5
names: Similarity
messages: Belongs to the UPF0758 family.

1302659:I858 RS05950
gene id: 1302659:I858_RS05950
uniprot id: A0A1B1RY05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1302659:I858 RS00135
gene id: 1302659:I858_RS00135
uniprot id: A0A1B1S109
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1302659:I858 RS12545
gene id: 1302659:I858_RS12545
uniprot id: A0A1B1S360
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS12675
gene id: 1302659:I858_RS12675
uniprot id: A0A1B1S333
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FemABX family.
messages: Cytoplasm

1302659:I858 RS12260
gene id: 1302659:I858_RS12260
uniprot id: A0A1B1S3B9
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1302659:I858 RS07315
gene id: 1302659:I858_RS07315
uniprot id: A0A1B1RXB3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1302659:I858 RS01145
gene id: 1302659:I858_RS01145
uniprot id: A0A1B1S0I9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1302659:I858 RS06720
gene id: 1302659:I858_RS06720
uniprot id: A0A1B1RXM2
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1302659:I858 RS01545
gene id: 1302659:I858_RS01545
uniprot id: A0A1B1S0A7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1302659:I858 RS04415
gene id: 1302659:I858_RS04415
uniprot id: A0A1B1RYR5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1302659:I858 RS11985
gene id: 1302659:I858_RS11985
uniprot id: A0A1B1S3H6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1302659:I858 RS07985
gene id: 1302659:I858_RS07985
uniprot id: A0A1B1S5Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS00910
gene id: 1302659:I858_RS00910
uniprot id: A0A1B1S0P8
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS00290
gene id: 1302659:I858_RS00290
uniprot id: A0A1B1S0Z3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1302659:I858 RS13200
gene id: 1302659:I858_RS13200
uniprot id: A0A1B1S2T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1302659:I858 RS00570
gene id: 1302659:I858_RS00570
uniprot id: A0A1B1S0W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1302659:I858 RS05340
gene id: 1302659:I858_RS05340
uniprot id: A0A1B1RYA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1302659:I858 RS10470
gene id: 1302659:I858_RS10470
uniprot id: A0A1B1S4G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

1302659:I858 RS10365
gene id: 1302659:I858_RS10365
uniprot id: A0A1B1S4C6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1302659:I858 RS00695
gene id: 1302659:I858_RS00695
uniprot id: A0A1B1S0R7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1302659:I858 RS00770
gene id: 1302659:I858_RS00770
uniprot id: A0A1B1S0S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1302659:I858 RS01060
gene id: 1302659:I858_RS01060
uniprot id: A0A1B1S0I7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1302659:I858 RS14325
gene id: 1302659:I858_RS14325
uniprot id: A0A1B1S261
names: Similarity
messages: Belongs to the TelA family.

1302659:I858 RS00225
gene id: 1302659:I858_RS00225
uniprot id: A0A1B1S100
names: Similarity
messages: Belongs to the RutC family.

1302659:I858 RS12805
gene id: 1302659:I858_RS12805
uniprot id: A0A1B1S314
names: Subcellular Location Annotation
messages: Cytoplasm

1302659:I858 RS09445
gene id: 1302659:I858_RS09445
uniprot id: A0A1B1S4V1
names: Similarity
messages: Belongs to the peptidase S41A family.

1302659:I858 RS14405
gene id: 1302659:I858_RS14405
uniprot id: A0A1B1S264
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS00310
gene id: 1302659:I858_RS00310
uniprot id: A0A1B1S0V8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1302659:I858 RS03175
gene id: 1302659:I858_RS03175
uniprot id: A0A1B1RZH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1302659:I858 RS04310
gene id: 1302659:I858_RS04310
uniprot id: A0A1B1RYU0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1302659:I858 RS04550
gene id: 1302659:I858_RS04550
uniprot id: A0A1B1RYQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS06170
gene id: 1302659:I858_RS06170
uniprot id: A0A1B1RXX6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

1302659:I858 RS13825
gene id: 1302659:I858_RS13825
uniprot id: A0A1B1S2J5
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS11380
gene id: 1302659:I858_RS11380
uniprot id: A0A1B1S3T4
names: Similarity
messages: Belongs to the UPF0637 family.

1302659:I858 RS11315
gene id: 1302659:I858_RS11315
uniprot id: A0A1B1S3V1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Interacts with CtaA.
messages: Membrane

1302659:I858 RS06345
gene id: 1302659:I858_RS06345
uniprot id: A0A1B1RXV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1302659:I858 RS06315
gene id: 1302659:I858_RS06315
uniprot id: A0A1B1RXV7
names: Function
messages: Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.

1302659:I858 RS03500
gene id: 1302659:I858_RS03500
uniprot id: A0A1B1RZ93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1302659:I858 RS05080
gene id: 1302659:I858_RS05080
uniprot id: A0A1B1RYH3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1302659:I858 RS12495
gene id: 1302659:I858_RS12495
uniprot id: A0A1B1S370
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS06935
gene id: 1302659:I858_RS06935
uniprot id: A0A1B1RXG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

1302659:I858 RS04670
gene id: 1302659:I858_RS04670
uniprot id: A0A1B1RYL2
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1302659:I858 RS06815
gene id: 1302659:I858_RS06815
uniprot id: A0A1B1RXK1
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1302659:I858 RS05990
gene id: 1302659:I858_RS05990
uniprot id: A0A1B1RY11
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1302659:I858 RS07265
gene id: 1302659:I858_RS07265
uniprot id: A0A1B1RXC2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1302659:I858 RS14820
gene id: 1302659:I858_RS14820
uniprot id: A0A1B1S1W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Membrane

1302659:I858 RS11030
gene id: 1302659:I858_RS11030
uniprot id: A0A1B1S401
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS04115
gene id: 1302659:I858_RS04115
uniprot id: A0A1B1RYY4
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1302659:I858 RS12635
gene id: 1302659:I858_RS12635
uniprot id: A0A1B1S342
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1302659:I858 RS10555
gene id: 1302659:I858_RS10555
uniprot id: A0A1B1S498
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1302659:I858 RS14290
gene id: 1302659:I858_RS14290
uniprot id: A0A1B1S265
names: Similarity
messages: Belongs to the HMG-CoA lyase family.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1302659:I858 RS06410
gene id: 1302659:I858_RS06410
uniprot id: A0A1B1RXT1
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS05975
gene id: 1302659:I858_RS05975
uniprot id: A0A1B1RY24
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1302659:I858 RS11225
gene id: 1302659:I858_RS11225
uniprot id: A0A1B1S3W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm

1302659:I858 RS04395
gene id: 1302659:I858_RS04395
uniprot id: A0A1B1RYT4
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1302659:I858 RS13770
gene id: 1302659:I858_RS13770
uniprot id: A0A1B1S2H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1302659:I858 RS10050
gene id: 1302659:I858_RS10050
uniprot id: A0A1B1S4K1
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1302659:I858 RS07275
gene id: 1302659:I858_RS07275
uniprot id: A0A1B1RXA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1302659:I858 RS00050
gene id: 1302659:I858_RS00050
uniprot id: A0A1B1S150
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1302659:I858 RS00545
gene id: 1302659:I858_RS00545
uniprot id: A0A1B1S0Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1302659:I858 RS14990
gene id: 1302659:I858_RS14990
uniprot id: A0A1B1S1T5
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS10775
gene id: 1302659:I858_RS10775
uniprot id: A0A1B1S4A0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1302659:I858 RS12810
gene id: 1302659:I858_RS12810
uniprot id: A0A1B1S312
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS07400
gene id: 1302659:I858_RS07400
uniprot id: A0A1B1RX93
names: PTM
messages: Binds 1 heme c group covalently per subunit.

1302659:I858 RS00700
gene id: 1302659:I858_RS00700
uniprot id: A0A1B1S0V0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1302659:I858 RS10290
gene id: 1302659:I858_RS10290
uniprot id: A0A1B1S4F6
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS00735
gene id: 1302659:I858_RS00735
uniprot id: A0A1B1S0S0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1302659:I858 RS00340
gene id: 1302659:I858_RS00340
uniprot id: A0A1B1S0Y4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1302659:I858 RS10440
gene id: 1302659:I858_RS10440
uniprot id: A0A1B1S4B7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1302659:I858 RS00460
gene id: 1302659:I858_RS00460
uniprot id: A0A1B1S0Y3
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1302659:I858 RS02535
gene id: 1302659:I858_RS02535
uniprot id: A0A1B1RZT6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1302659:I858 RS13445
gene id: 1302659:I858_RS13445
uniprot id: A0A1B1S2N9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RpoE family.
messages: Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors.

1302659:I858 RS02095
gene id: 1302659:I858_RS02095
uniprot id: A0A1B1S005
names: Subcellular Location Annotation
messages: Cytoplasm

1302659:I858 RS16215
gene id: 1302659:I858_RS16215
uniprot id: A0A1B1S144
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1302659:I858 RS14205
gene id: 1302659:I858_RS14205
uniprot id: A0A1B1S2A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family. YeeN subfamily.
messages: Cytoplasm

1302659:I858 RS16230
gene id: 1302659:I858_RS16230
uniprot id: A0A1B1S149
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1302659:I858 RS10340
gene id: 1302659:I858_RS10340
uniprot id: A0A1B1S4E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1302659:I858 RS03570
gene id: 1302659:I858_RS03570
uniprot id: A0A1B1RZ88
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1302659:I858 RS05760
gene id: 1302659:I858_RS05760
uniprot id: A0A1B1RY47
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1302659:I858 RS15240
gene id: 1302659:I858_RS15240
uniprot id: A0A1B1S1R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family. NanA subfamily.
messages: Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.
messages: Cytoplasm
messages: Homotetramer.

1302659:I858 RS13015
gene id: 1302659:I858_RS13015
uniprot id: A0A1B1S2X0
names: Similarity
messages: Belongs to the CpsD/CapB family.

1302659:I858 RS00610
gene id: 1302659:I858_RS00610
uniprot id: A0A1B1S0U8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1302659:I858 RS13765
gene id: 1302659:I858_RS13765
uniprot id: A0A1B1S2H9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1302659:I858 RS11600
gene id: 1302659:I858_RS11600
uniprot id: A0A1B1S3N5
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS05315
gene id: 1302659:I858_RS05315
uniprot id: A0A1B1RYB6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1302659:I858 RS01820
gene id: 1302659:I858_RS01820
uniprot id: A0A1B1S070
names: Similarity
messages: Belongs to the UPF0398 family.

1302659:I858 RS06455
gene id: 1302659:I858_RS06455
uniprot id: A0A1B1RXR9
names: Similarity
messages: Belongs to the universal stress protein A family.

1302659:I858 RS12595
gene id: 1302659:I858_RS12595
uniprot id: A0A1B1S350
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FemABX family.
messages: Cytoplasm

1302659:I858 RS06835
gene id: 1302659:I858_RS06835
uniprot id: A0A1B1RXJ0
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1302659:I858 RS05700
gene id: 1302659:I858_RS05700
uniprot id: A0A1B1RY40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS13400
gene id: 1302659:I858_RS13400
uniprot id: A0A1B1S2P8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1302659:I858 RS08955
gene id: 1302659:I858_RS08955
uniprot id: A0A1B1S560
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1302659:I858 RS10630
gene id: 1302659:I858_RS10630
uniprot id: A0A1B1S490
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1302659:I858 RS06375
gene id: 1302659:I858_RS06375
uniprot id: A0A1B1RXS5
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1302659:I858 RS09270
gene id: 1302659:I858_RS09270
uniprot id: A0A1B1S514
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.

1302659:I858 RS08690
gene id: 1302659:I858_RS08690
uniprot id: A0A1B1S5B7
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1302659:I858 RS06800
gene id: 1302659:I858_RS06800
uniprot id: A0A1B1RXL3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1302659:I858 RS09100
gene id: 1302659:I858_RS09100
uniprot id: A0A1B1S535
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS07320
gene id: 1302659:I858_RS07320
uniprot id: A0A1B1RXA7
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS06730
gene id: 1302659:I858_RS06730
uniprot id: A0A1B1RXK7
names: Similarity
messages: Belongs to the thioredoxin family.

1302659:I858 RS08870
gene id: 1302659:I858_RS08870
uniprot id: A0A1B1S576
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1302659:I858 RS01770
gene id: 1302659:I858_RS01770
uniprot id: A0A1B1S079
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS14040
gene id: 1302659:I858_RS14040
uniprot id: A0A1B1S2C5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1302659:I858 RS00430
gene id: 1302659:I858_RS00430
uniprot id: A0A1B1S0X1
names: Similarity
messages: Belongs to the CtsR family.

1302659:I858 RS10110
gene id: 1302659:I858_RS10110
uniprot id: A0A1B1S4I4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1302659:I858 RS03055
gene id: 1302659:I858_RS03055
uniprot id: A0A1B1RZK0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1302659:I858 RS05775
gene id: 1302659:I858_RS05775
uniprot id: A0A1B1RY31
names: Similarity
messages: Belongs to the EamA transporter family.

1302659:I858 RS13230
gene id: 1302659:I858_RS13230
uniprot id: A0A1B1S2T4
names: Similarity
messages: Belongs to the peptidase S66 family.

1302659:I858 RS01050
gene id: 1302659:I858_RS01050
uniprot id: A0A1B1S0L0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1302659:I858 RS15875
gene id: 1302659:I858_RS15875
uniprot id: A0A1B1S1A8
names: Similarity
messages: Belongs to the peptidase S51 family.

1302659:I858 RS11000
gene id: 1302659:I858_RS11000
uniprot id: A0A1B1S405
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS12980
gene id: 1302659:I858_RS12980
uniprot id: A0A1B1S2Y7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1302659:I858 RS01150
gene id: 1302659:I858_RS01150
uniprot id: A0A1B1S0J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1302659:I858 RS13500
gene id: 1302659:I858_RS13500
uniprot id: A0A1B1S2N7
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1302659:I858 RS02300
gene id: 1302659:I858_RS02300
uniprot id: A0A1B1RZY9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1302659:I858 RS04300
gene id: 1302659:I858_RS04300
uniprot id: A0A1B1RYT9
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1302659:I858 RS06780
gene id: 1302659:I858_RS06780
uniprot id: A0A1B1RXK0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1302659:I858 RS14255
gene id: 1302659:I858_RS14255
uniprot id: A0A1B1S292
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS14360
gene id: 1302659:I858_RS14360
uniprot id: A0A1B1S262
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

1302659:I858 RS04900
gene id: 1302659:I858_RS04900
uniprot id: A0A1B1RYL1
names: Similarity
messages: Belongs to the UPF0111 family.

1302659:I858 RS03990
gene id: 1302659:I858_RS03990
uniprot id: A0A1B1RZ14
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1302659:I858 RS05590
gene id: 1302659:I858_RS05590
uniprot id: A0A1B1RY60
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1302659:I858 RS04150
gene id: 1302659:I858_RS04150
uniprot id: A0A1B1RYW9
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1302659:I858 RS02810
gene id: 1302659:I858_RS02810
uniprot id: A0A1B1RZQ3
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

1302659:I858 RS07135
gene id: 1302659:I858_RS07135
uniprot id: A0A1B1RXE3
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1302659:I858 RS04010
gene id: 1302659:I858_RS04010
uniprot id: A0A1B1RZ02
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1302659:I858 RS01120
gene id: 1302659:I858_RS01120
uniprot id: A0A1B1S0L3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

1302659:I858 RS07295
gene id: 1302659:I858_RS07295
uniprot id: A0A1B1RX99
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1302659:I858 RS13285
gene id: 1302659:I858_RS13285
uniprot id: A0A1B1S2S2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS06505
gene id: 1302659:I858_RS06505
uniprot id: A0A1B1RXQ4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS08790
gene id: 1302659:I858_RS08790
uniprot id: A0A1B1S586
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1302659:I858 RS02425
gene id: 1302659:I858_RS02425
uniprot id: A0A1B1RZW6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Central regulator of manganese homeostasis.
messages: Cytoplasm
messages: DNA binding is strongly activated by Mn(2+).
messages: Homodimer.

1302659:I858 RS15935
gene id: 1302659:I858_RS15935
uniprot id: A0A1B1S1D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1302659:I858 RS05230
gene id: 1302659:I858_RS05230
uniprot id: A0A1B1RYE0
names: Similarity
messages: Belongs to the peptidase S9C family.

1302659:I858 RS13315
gene id: 1302659:I858_RS13315
uniprot id: A0A1B1S2U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1302659:I858 RS10115
gene id: 1302659:I858_RS10115
uniprot id: A0A1B1S4H6
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

1302659:I858 RS04640
gene id: 1302659:I858_RS04640
uniprot id: A0A1B1RYN1
names: Similarity
messages: Belongs to the UPF0435 family.

1302659:I858 RS03820
gene id: 1302659:I858_RS03820
uniprot id: A0A1B1RZ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1302659:I858 RS06435
gene id: 1302659:I858_RS06435
uniprot id: A0A1B1RXU2
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS00235
gene id: 1302659:I858_RS00235
uniprot id: A0A1B1S0Z0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS06530
gene id: 1302659:I858_RS06530
uniprot id: A0A1B1RXQ5
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1302659:I858 RS05290
gene id: 1302659:I858_RS05290
uniprot id: A0A1B1RYB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1302659:I858 RS03000
gene id: 1302659:I858_RS03000
uniprot id: A0A1B1RZL2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1302659:I858 RS10535
gene id: 1302659:I858_RS10535
uniprot id: A0A1B1S484
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1302659:I858 RS00805
gene id: 1302659:I858_RS00805
uniprot id: A0A1B1S0M6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1302659:I858 RS00175
gene id: 1302659:I858_RS00175
uniprot id: A0A1B1S114
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1302659:I858 RS01560
gene id: 1302659:I858_RS01560
uniprot id: A0A1B1S084
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1302659:I858 RS07090
gene id: 1302659:I858_RS07090
uniprot id: A0A1B1RXE8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1302659:I858 RS11855
gene id: 1302659:I858_RS11855
uniprot id: A0A1B1S3I4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1302659:I858 RS12125
gene id: 1302659:I858_RS12125
uniprot id: A0A1B1S3C1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1302659:I858 RS07815
gene id: 1302659:I858_RS07815
uniprot id: A0A1B1RX10
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.

1302659:I858 RS15760
gene id: 1302659:I858_RS15760
uniprot id: A0A1B1S1C6
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS06400
gene id: 1302659:I858_RS06400
uniprot id: A0A1B1RXT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1302659:I858 RS13020
gene id: 1302659:I858_RS13020
uniprot id: A0A1B1S2X2
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS01140
gene id: 1302659:I858_RS01140
uniprot id: A0A1B1S0K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1302659:I858 RS11995
gene id: 1302659:I858_RS11995
uniprot id: A0A1B1S3G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1302659:I858 RS11055
gene id: 1302659:I858_RS11055
uniprot id: A0A1B1S3Z5
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1302659:I858 RS08820
gene id: 1302659:I858_RS08820
uniprot id: A0A1B1S585
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ComGC family.
messages: Cell membrane
messages: Homodimer.
messages: Required for transformation and DNA binding.

1302659:I858 RS01070
gene id: 1302659:I858_RS01070
uniprot id: A0A1B1S0M3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1302659:I858 RS10040
gene id: 1302659:I858_RS10040
uniprot id: A0A1B1S4K6
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1302659:I858 RS05445
gene id: 1302659:I858_RS05445
uniprot id: A0A1B1RY89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1302659:I858 RS06840
gene id: 1302659:I858_RS06840
uniprot id: A0A1B1RXJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

1302659:I858 RS11175
gene id: 1302659:I858_RS11175
uniprot id: A0A1B1S3X3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1302659:I858 RS11230
gene id: 1302659:I858_RS11230
uniprot id: A0A1B1S3W5
names: Similarity
messages: Belongs to the peptidase S16 family.

1302659:I858 RS14320
gene id: 1302659:I858_RS14320
uniprot id: A0A1B1S268
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

1302659:I858 RS06185
gene id: 1302659:I858_RS06185
uniprot id: A0A1B1RXY7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1302659:I858 RS10935
gene id: 1302659:I858_RS10935
uniprot id: A0A1B1S429
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1302659:I858 RS08865
gene id: 1302659:I858_RS08865
uniprot id: A0A1B1S583
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1302659:I858 RS04500
gene id: 1302659:I858_RS04500
uniprot id: A0A1B1RYR4
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1302659:I858 RS01495
gene id: 1302659:I858_RS01495
uniprot id: A0A1B1S0B5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1302659:I858 RS05310
gene id: 1302659:I858_RS05310
uniprot id: A0A1B1RYB4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1302659:I858 RS07110
gene id: 1302659:I858_RS07110
uniprot id: A0A1B1RXF4
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1302659:I858 RS09380
gene id: 1302659:I858_RS09380
uniprot id: A0A1B1S4X5
names: Similarity
messages: Belongs to the TelA family.

1302659:I858 RS08655
gene id: 1302659:I858_RS08655
uniprot id: A0A1B1S5B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1302659:I858 RS11300
gene id: 1302659:I858_RS11300
uniprot id: A0A1B1S3U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS15755
gene id: 1302659:I858_RS15755
uniprot id: A0A1B1S1H9
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1302659:I858 RS02770
gene id: 1302659:I858_RS02770
uniprot id: A0A1B1RZN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1302659:I858 RS04385
gene id: 1302659:I858_RS04385
uniprot id: A0A1B1RYT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1302659:I858 RS04025
gene id: 1302659:I858_RS04025
uniprot id: A0A1B1RZ11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons.
messages: Membrane

1302659:I858 RS01585
gene id: 1302659:I858_RS01585
uniprot id: A0A1B1S0A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1302659:I858 RS04255
gene id: 1302659:I858_RS04255
uniprot id: A0A1B1RYU8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1302659:I858 RS07905
gene id: 1302659:I858_RS07905
uniprot id: A0A1B1S5R9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

1302659:I858 RS13270
gene id: 1302659:I858_RS13270
uniprot id: A0A1B1S2S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1302659:I858 RS02330
gene id: 1302659:I858_RS02330
uniprot id: A0A1B1RZT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1302659:I858 RS14220
gene id: 1302659:I858_RS14220
uniprot id: A0A1B1S289
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1302659:I858 RS01065
gene id: 1302659:I858_RS01065
uniprot id: A0A1B1S0M4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1302659:I858 RS06735
gene id: 1302659:I858_RS06735
uniprot id: A0A1B1RXL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1302659:I858 RS02805
gene id: 1302659:I858_RS02805
uniprot id: A0A1B1RZN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1302659:I858 RS14785
gene id: 1302659:I858_RS14785
uniprot id: A0A1B1S1X4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1302659:I858 RS03640
gene id: 1302659:I858_RS03640
uniprot id: A0A1B1RZ63
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1302659:I858 RS06990
gene id: 1302659:I858_RS06990
uniprot id: A0A1B1RXG6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1302659:I858 RS00765
gene id: 1302659:I858_RS00765
uniprot id: A0A1B1S0S3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1302659:I858 RS07190
gene id: 1302659:I858_RS07190
uniprot id: A0A1B1RXC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1302659:I858 RS01720
gene id: 1302659:I858_RS01720
uniprot id: A0A1B1S090
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1302659:I858 RS00200
gene id: 1302659:I858_RS00200
uniprot id: A0A1B1S0X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

1302659:I858 RS04690
gene id: 1302659:I858_RS04690
uniprot id: A0A1B1RYM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1302659:I858 RS13295
gene id: 1302659:I858_RS13295
uniprot id: A0A1B1S2S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1302659:I858 RS15230
gene id: 1302659:I858_RS15230
uniprot id: A0A1B1S1P5
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS00525
gene id: 1302659:I858_RS00525
uniprot id: A0A1B1S0V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1302659:I858 RS06960
gene id: 1302659:I858_RS06960
uniprot id: A0A1B1RXI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1302659:I858 RS11725
gene id: 1302659:I858_RS11725
uniprot id: A0A1B1S3N3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1302659:I858 RS00615
gene id: 1302659:I858_RS00615
uniprot id: A0A1B1S0V1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1302659:I858 RS06910
gene id: 1302659:I858_RS06910
uniprot id: A0A1B1RXI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS06235
gene id: 1302659:I858_RS06235
uniprot id: A0A1B1RXW4
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1302659:I858 RS05925
gene id: 1302659:I858_RS05925
uniprot id: A0A1B1RY33
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
messages: Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).

1302659:I858 RS01970
gene id: 1302659:I858_RS01970
uniprot id: A0A1B1S043
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1302659:I858 RS12160
gene id: 1302659:I858_RS12160
uniprot id: A0A1B1S3D8
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1302659:I858 RS08015
gene id: 1302659:I858_RS08015
uniprot id: A0A1B1S5P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS01715
gene id: 1302659:I858_RS01715
uniprot id: A0A1B1S052
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1302659:I858 RS08745
gene id: 1302659:I858_RS08745
uniprot id: A0A1B1S5A7
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1302659:I858 RS13320
gene id: 1302659:I858_RS13320
uniprot id: A0A1B1S2R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1302659:I858 RS01980
gene id: 1302659:I858_RS01980
uniprot id: A0A1B1S041
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS08900
gene id: 1302659:I858_RS08900
uniprot id: A0A1B1S568
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1302659:I858 RS05585
gene id: 1302659:I858_RS05585
uniprot id: A0A1B1RY85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS16210
gene id: 1302659:I858_RS16210
uniprot id: A0A1B1S157
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1302659:I858 RS11840
gene id: 1302659:I858_RS11840
uniprot id: A0A1B1S3N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS05035
gene id: 1302659:I858_RS05035
uniprot id: A0A1B1RYG2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS07120
gene id: 1302659:I858_RS07120
uniprot id: A0A1B1RXE1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1302659:I858 RS11815
gene id: 1302659:I858_RS11815
uniprot id: A0A1B1S3K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS08925
gene id: 1302659:I858_RS08925
uniprot id: A0A1B1S587
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

1302659:I858 RS10525
gene id: 1302659:I858_RS10525
uniprot id: A0A1B1S4F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1302659:I858 RS12395
gene id: 1302659:I858_RS12395
uniprot id: A0A1B1S389
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1302659:I858 RS06255
gene id: 1302659:I858_RS06255
uniprot id: A0A1B1RXW8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1302659:I858 RS07020
gene id: 1302659:I858_RS07020
uniprot id: A0A1B1RXF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1302659:I858 RS12630
gene id: 1302659:I858_RS12630
uniprot id: A0A1B1S324
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FemABX family.
messages: Cytoplasm

1302659:I858 RS01640
gene id: 1302659:I858_RS01640
uniprot id: A0A1B1S099
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

1302659:I858 RS12185
gene id: 1302659:I858_RS12185
uniprot id: A0A1B1S3D2
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS00685
gene id: 1302659:I858_RS00685
uniprot id: A0A1B1S0T1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1302659:I858 RS00775
gene id: 1302659:I858_RS00775
uniprot id: A0A1B1S0S9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

1302659:I858 RS11050
gene id: 1302659:I858_RS11050
uniprot id: A0A1B1S3Z6
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS10925
gene id: 1302659:I858_RS10925
uniprot id: A0A1B1S421
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1302659:I858 RS11235
gene id: 1302659:I858_RS11235
uniprot id: A0A1B1S412
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1302659:I858 RS10465
gene id: 1302659:I858_RS10465
uniprot id: A0A1B1S4A6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1302659:I858 RS11075
gene id: 1302659:I858_RS11075
uniprot id: A0A1B1S3Z4
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

1302659:I858 RS13585
gene id: 1302659:I858_RS13585
uniprot id: A0A1B1S2K2
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1302659:I858 RS08725
gene id: 1302659:I858_RS08725
uniprot id: A0A1B1S5A4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS02335
gene id: 1302659:I858_RS02335
uniprot id: A0A1B1RZX6
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1302659:I858 RS15510
gene id: 1302659:I858_RS15510
uniprot id: A0A1B1S1J0
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

1302659:I858 RS09880
gene id: 1302659:I858_RS09880
uniprot id: A0A1B1S4N6
names: Similarity
messages: Belongs to the cytochrome P450 family.

1302659:I858 RS00730
gene id: 1302659:I858_RS00730
uniprot id: A0A1B1S0R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1302659:I858 RS14970
gene id: 1302659:I858_RS14970
uniprot id: A0A1B1S1U2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1302659:I858 RS10140
gene id: 1302659:I858_RS10140
uniprot id: A0A1B1S4I7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1302659:I858 RS01030
gene id: 1302659:I858_RS01030
uniprot id: A0A1B1S0P1
names: Similarity
messages: Belongs to the FlgM family.

1302659:I858 RS05710
gene id: 1302659:I858_RS05710
uniprot id: A0A1B1RY51
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1302659:I858 RS10960
gene id: 1302659:I858_RS10960
uniprot id: A0A1B1S422
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1302659:I858 RS11110
gene id: 1302659:I858_RS11110
uniprot id: A0A1B1S3Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1302659:I858 RS13940
gene id: 1302659:I858_RS13940
uniprot id: A0A1B1S2E5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1302659:I858 RS13305
gene id: 1302659:I858_RS13305
uniprot id: A0A1B1S2R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1302659:I858 RS01245
gene id: 1302659:I858_RS01245
uniprot id: A0A1B1S0G9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1302659:I858 RS15015
gene id: 1302659:I858_RS15015
uniprot id: A0A1B1S1S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1302659:I858 RS07790
gene id: 1302659:I858_RS07790
uniprot id: A0A1B1RX20
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1302659:I858 RS10835
gene id: 1302659:I858_RS10835
uniprot id: A0A1B1S423
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1302659:I858 RS14840
gene id: 1302659:I858_RS14840
uniprot id: A0A1B1S1W6
names: Similarity
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family.

1302659:I858 RS13120
gene id: 1302659:I858_RS13120
uniprot id: A0A1B1S2V5
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1302659:I858 RS11330
gene id: 1302659:I858_RS11330
uniprot id: A0A1B1S3U3
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS10215
gene id: 1302659:I858_RS10215
uniprot id: A0A1B1S4F7
names: Similarity
messages: Belongs to the asparaginase 1 family.

1302659:I858 RS14355
gene id: 1302659:I858_RS14355
uniprot id: A0A1B1S274
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

1302659:I858 RS00645
gene id: 1302659:I858_RS00645
uniprot id: A0A1B1S0T0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1302659:I858 RS04685
gene id: 1302659:I858_RS04685
uniprot id: A0A1B1RYL5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1302659:I858 RS05750
gene id: 1302659:I858_RS05750
uniprot id: A0A1B1RY30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.
messages: Catalyzes the interconversion of ornithine to glutamate semialdehyde.
messages: Cytoplasm

1302659:I858 RS02380
gene id: 1302659:I858_RS02380
uniprot id: A0A1B1RZS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1302659:I858 RS10485
gene id: 1302659:I858_RS10485
uniprot id: A0A1B1S4B1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1302659:I858 RS00090
gene id: 1302659:I858_RS00090
uniprot id: A0A1B1S125
names: Similarity
messages: Belongs to the DCK/DGK family.

1302659:I858 RS14695
gene id: 1302659:I858_RS14695
uniprot id: A0A1B1S1Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. L-carnitine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3-dehydrocarnitine.
messages: Cytoplasm
messages: Homodimer.

1302659:I858 RS09560
gene id: 1302659:I858_RS09560
uniprot id: A0A1B1S4S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1302659:I858 RS00655
gene id: 1302659:I858_RS00655
uniprot id: A0A1B1S0Q8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1302659:I858 RS09915
gene id: 1302659:I858_RS09915
uniprot id: A0A1B1S4R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1302659:I858 RS15375
gene id: 1302659:I858_RS15375
uniprot id: A0A1B1S1K2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1302659:I858 RS09805
gene id: 1302659:I858_RS09805
uniprot id: A0A1B1S4U0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

1302659:I858 RS01490
gene id: 1302659:I858_RS01490
uniprot id: A0A1B1S0C7
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1302659:I858 RS14170
gene id: 1302659:I858_RS14170
uniprot id: A0A1B1S293
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1302659:I858 RS13725
gene id: 1302659:I858_RS13725
uniprot id: A0A1B1S2L5
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1302659:I858 RS09490
gene id: 1302659:I858_RS09490
uniprot id: A0A1B1S4V0
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1302659:I858 RS03095
gene id: 1302659:I858_RS03095
uniprot id: A0A1B1RZJ1
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

1302659:I858 RS05705
gene id: 1302659:I858_RS05705
uniprot id: A0A1B1RY52
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1302659:I858 RS03765
gene id: 1302659:I858_RS03765
uniprot id: A0A1B1RZ17
names: Similarity
messages: Belongs to the creatininase superfamily.

1302659:I858 RS00625
gene id: 1302659:I858_RS00625
uniprot id: A0A1B1S0V7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1302659:I858 RS00240
gene id: 1302659:I858_RS00240
uniprot id: A0A1B1S0Y9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1302659:I858 RS08125
gene id: 1302659:I858_RS08125
uniprot id: A0A1B1S5M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1302659:I858 RS06390
gene id: 1302659:I858_RS06390
uniprot id: A0A1B1RXU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1302659:I858 RS00250
gene id: 1302659:I858_RS00250
uniprot id: A0A1B1S0W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1302659:I858 RS11940
gene id: 1302659:I858_RS11940
uniprot id: A0A1B1S3H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1302659:I858 RS13570
gene id: 1302659:I858_RS13570
uniprot id: A0A1B1S2L7
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1302659:I858 RS09655
gene id: 1302659:I858_RS09655
uniprot id: A0A1B1S4W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS04520
gene id: 1302659:I858_RS04520
uniprot id: A0A1B1RYP2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1302659:I858 RS06825
gene id: 1302659:I858_RS06825
uniprot id: A0A1B1RXK3
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS13640
gene id: 1302659:I858_RS13640
uniprot id: A0A1B1S2K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS04430
gene id: 1302659:I858_RS04430
uniprot id: A0A1B1RYR6
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1302659:I858 RS02775
gene id: 1302659:I858_RS02775
uniprot id: A0A1B1RZN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1302659:I858 RS14795
gene id: 1302659:I858_RS14795
uniprot id: A0A1B1S1X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS05495
gene id: 1302659:I858_RS05495
uniprot id: A0A1B1RY96
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1302659:I858 RS16235
gene id: 1302659:I858_RS16235
uniprot id: A0A1B1S155
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1302659:I858 RS16300
gene id: 1302659:I858_RS16300
uniprot id: A0A1B1S154
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS12930
gene id: 1302659:I858_RS12930
uniprot id: A0A1B1S2Z6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1302659:I858 RS16315
gene id: 1302659:I858_RS16315
uniprot id: A0A1B1S135
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1302659:I858 RS12970
gene id: 1302659:I858_RS12970
uniprot id: A0A1B1S2Y0
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1302659:I858 RS12670
gene id: 1302659:I858_RS12670
uniprot id: A0A1B1S378
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FemABX family.
messages: Cytoplasm

1302659:I858 RS02575
gene id: 1302659:I858_RS02575
uniprot id: A0A1B1RZT3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1302659:I858 RS01985
gene id: 1302659:I858_RS01985
uniprot id: A0A1B1S056
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS02235
gene id: 1302659:I858_RS02235
uniprot id: A0A1B1RZZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1302659:I858 RS00750
gene id: 1302659:I858_RS00750
uniprot id: A0A1B1S0T8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1302659:I858 RS10285
gene id: 1302659:I858_RS10285
uniprot id: A0A1B1S4E8
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS14250
gene id: 1302659:I858_RS14250
uniprot id: A0A1B1S280
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1302659:I858 RS10805
gene id: 1302659:I858_RS10805
uniprot id: A0A1B1S451
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1302659:I858 RS10305
gene id: 1302659:I858_RS10305
uniprot id: A0A1B1S4F0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

1302659:I858 RS08830
gene id: 1302659:I858_RS08830
uniprot id: A0A1B1S582
names: Similarity
messages: Belongs to the GSP E family.

1302659:I858 RS11125
gene id: 1302659:I858_RS11125
uniprot id: A0A1B1S3Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1302659:I858 RS00055
gene id: 1302659:I858_RS00055
uniprot id: A0A1B1S139
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1302659:I858 RS00030
gene id: 1302659:I858_RS00030
uniprot id: A0A1B1S147
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1302659:I858 RS05425
gene id: 1302659:I858_RS05425
uniprot id: A0A1B1RYB1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1302659:I858 RS04720
gene id: 1302659:I858_RS04720
uniprot id: A0A1B1RYK2
names: Similarity
messages: Belongs to the UPF0374 family.

1302659:I858 RS10205
gene id: 1302659:I858_RS10205
uniprot id: A0A1B1S4H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1302659:I858 RS00065
gene id: 1302659:I858_RS00065
uniprot id: A0A1B1S120
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS13875
gene id: 1302659:I858_RS13875
uniprot id: A0A1B1S2I5
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

1302659:I858 RS05165
gene id: 1302659:I858_RS05165
uniprot id: A0A1B1RYF5
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS02755
gene id: 1302659:I858_RS02755
uniprot id: A0A1B1RZP7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1302659:I858 RS14530
gene id: 1302659:I858_RS14530
uniprot id: A0A1B1S227
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS03440
gene id: 1302659:I858_RS03440
uniprot id: A0A1B1RZA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1302659:I858 RS07660
gene id: 1302659:I858_RS07660
uniprot id: A0A1B1RX38
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1302659:I858 RS01230
gene id: 1302659:I858_RS01230
uniprot id: A0A1B1S0K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS10965
gene id: 1302659:I858_RS10965
uniprot id: A0A1B1S428
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1302659:I858 RS13525
gene id: 1302659:I858_RS13525
uniprot id: A0A1B1S2Q4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1302659:I858 RS08685
gene id: 1302659:I858_RS08685
uniprot id: A0A1B1S5A3
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box).
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1302659:I858 RS13310
gene id: 1302659:I858_RS13310
uniprot id: A0A1B1S2R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1302659:I858 RS00885
gene id: 1302659:I858_RS00885
uniprot id: A0A1B1S0P9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1302659:I858 RS14285
gene id: 1302659:I858_RS14285
uniprot id: A0A1B1S266
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1302659:I858 RS04675
gene id: 1302659:I858_RS04675
uniprot id: A0A1B1RYN8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1302659:I858 RS05910
gene id: 1302659:I858_RS05910
uniprot id: A0A1B1RY44
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1302659:I858 RS16320
gene id: 1302659:I858_RS16320
uniprot id: A0A1B1S131
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1302659:I858 RS03560
gene id: 1302659:I858_RS03560
uniprot id: A0A1B1RZ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS10690
gene id: 1302659:I858_RS10690
uniprot id: A0A1B1S473
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1302659:I858 RS06880
gene id: 1302659:I858_RS06880
uniprot id: A0A1B1RXI9
names: Function
messages: Required for transformation and DNA binding.

1302659:I858 RS04320
gene id: 1302659:I858_RS04320
uniprot id: A0A1B1RYU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1302659:I858 RS08160
gene id: 1302659:I858_RS08160
uniprot id: A0A1B1S5L1
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1302659:I858 RS04295
gene id: 1302659:I858_RS04295
uniprot id: A0A1B1RYV2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1302659:I858 RS01960
gene id: 1302659:I858_RS01960
uniprot id: A0A1B1S057
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS07725
gene id: 1302659:I858_RS07725
uniprot id: A0A1B1RX34
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1302659:I858 RS06670
gene id: 1302659:I858_RS06670
uniprot id: A0A1B1RXN4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1302659:I858 RS02555
gene id: 1302659:I858_RS02555
uniprot id: A0A1B1RZQ9
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS03730
gene id: 1302659:I858_RS03730
uniprot id: A0A1B1RZ50
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1302659:I858 RS13890
gene id: 1302659:I858_RS13890
uniprot id: A0A1B1S2F3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1302659:I858 RS01590
gene id: 1302659:I858_RS01590
uniprot id: A0A1B1S0A9
names: Similarity
messages: Belongs to the catalase family.

1302659:I858 RS13945
gene id: 1302659:I858_RS13945
uniprot id: A0A1B1S2D7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

1302659:I858 RS14055
gene id: 1302659:I858_RS14055
uniprot id: A0A1B1S2C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1302659:I858 RS02650
gene id: 1302659:I858_RS02650
uniprot id: A0A1B1RZS3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1302659:I858 RS16630
gene id: 1302659:I858_RS16630
uniprot id: A0A1B1S5Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1302659:I858 RS16060
gene id: 1302659:I858_RS16060
uniprot id: A0A1B1S185
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS15000
gene id: 1302659:I858_RS15000
uniprot id: A0A1B1S1T0
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1302659:I858 RS14885
gene id: 1302659:I858_RS14885
uniprot id: A0A1B1S1V7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.
messages: Homotetramer.

1302659:I858 RS00755
gene id: 1302659:I858_RS00755
uniprot id: A0A1B1S0N6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1302659:I858 RS10820
gene id: 1302659:I858_RS10820
uniprot id: A0A1B1S437
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS10540
gene id: 1302659:I858_RS10540
uniprot id: A0A1B1S4A2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1302659:I858 RS02355
gene id: 1302659:I858_RS02355
uniprot id: A0A1B1RZU9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPase class C family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm

1302659:I858 RS08580
gene id: 1302659:I858_RS08580
uniprot id: A0A1B1S5D1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily.
messages: Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS00455
gene id: 1302659:I858_RS00455
uniprot id: A0A1B1S0X9
names: Similarity
messages: Belongs to the ycf81 family.

1302659:I858 RS07355
gene id: 1302659:I858_RS07355
uniprot id: A0A1B1RXA2
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1302659:I858 RS00295
gene id: 1302659:I858_RS00295
uniprot id: A0A1B1S0Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1302659:I858 RS03890
gene id: 1302659:I858_RS03890
uniprot id: A0A1B1RZ34
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS08880
gene id: 1302659:I858_RS08880
uniprot id: A0A1B1S579
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1302659:I858 RS11065
gene id: 1302659:I858_RS11065
uniprot id: A0A1B1S404
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1302659:I858 RS00865
gene id: 1302659:I858_RS00865
uniprot id: A0A1B1S0R5
names: Similarity
messages: Belongs to the citrate synthase family.

1302659:I858 RS10735
gene id: 1302659:I858_RS10735
uniprot id: A0A1B1S444
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1302659:I858 RS10325
gene id: 1302659:I858_RS10325
uniprot id: A0A1B1S4E5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1302659:I858 RS02140
gene id: 1302659:I858_RS02140
uniprot id: A0A1B1S013
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

1302659:I858 RS09760
gene id: 1302659:I858_RS09760
uniprot id: A0A1B1S4Q5
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1302659:I858 RS14630
gene id: 1302659:I858_RS14630
uniprot id: A0A1B1S214
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS00640
gene id: 1302659:I858_RS00640
uniprot id: A0A1B1S0T2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1302659:I858 RS05615
gene id: 1302659:I858_RS05615
uniprot id: A0A1B1RY73
names: Similarity
messages: Belongs to the HepT RNase toxin family.

1302659:I858 RS00320
gene id: 1302659:I858_RS00320
uniprot id: A0A1B1S0Y8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1302659:I858 RS02080
gene id: 1302659:I858_RS02080
uniprot id: A0A1B1S025
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS15515
gene id: 1302659:I858_RS15515
uniprot id: A0A1B1S1I5
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

1302659:I858 RS09840
gene id: 1302659:I858_RS09840
uniprot id: A0A1B1S4N7
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS10840
gene id: 1302659:I858_RS10840
uniprot id: A0A1B1S439
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1302659:I858 RS12400
gene id: 1302659:I858_RS12400
uniprot id: A0A1B1S394
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1302659:I858 RS07710
gene id: 1302659:I858_RS07710
uniprot id: A0A1B1RX28
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1302659:I858 RS06465
gene id: 1302659:I858_RS06465
uniprot id: A0A1B1RXS3
names: Similarity
messages: Belongs to the UPF0173 family.

1302659:I858 RS01155
gene id: 1302659:I858_RS01155
uniprot id: A0A1B1S0L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1302659:I858 RS00220
gene id: 1302659:I858_RS00220
uniprot id: A0A1B1S118
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

1302659:I858 RS14945
gene id: 1302659:I858_RS14945
uniprot id: A0A1B1S1U4
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS15745
gene id: 1302659:I858_RS15745
uniprot id: A0A1B1S1F3
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1302659:I858 RS14660
gene id: 1302659:I858_RS14660
uniprot id: A0A1B1S1Z4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1302659:I858 RS06585
gene id: 1302659:I858_RS06585
uniprot id: A0A1B1RXQ9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1302659:I858 RS02675
gene id: 1302659:I858_RS02675
uniprot id: A0A1B1RZQ6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

1302659:I858 RS07095
gene id: 1302659:I858_RS07095
uniprot id: A0A1B1RXF5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS14280
gene id: 1302659:I858_RS14280
uniprot id: A0A1B1S2B0
names: Similarity
messages: Belongs to the PrpD family.

1302659:I858 RS02565
gene id: 1302659:I858_RS02565
uniprot id: A0A1B1RZR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS00665
gene id: 1302659:I858_RS00665
uniprot id: A0A1B1S0U1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1302659:I858 RS07365
gene id: 1302659:I858_RS07365
uniprot id: A0A1B1RXA1
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1302659:I858 RS07170
gene id: 1302659:I858_RS07170
uniprot id: A0A1B1RXC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1302659:I858 RS03950
gene id: 1302659:I858_RS03950
uniprot id: A0A1B1RZ07
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS05220
gene id: 1302659:I858_RS05220
uniprot id: A0A1B1RYB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS13865
gene id: 1302659:I858_RS13865
uniprot id: A0A1B1S2F7
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1302659:I858 RS06775
gene id: 1302659:I858_RS06775
uniprot id: A0A1B1RXK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1302659:I858 RS08785
gene id: 1302659:I858_RS08785
uniprot id: A0A1B1S591
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1302659:I858 RS10885
gene id: 1302659:I858_RS10885
uniprot id: A0A1B1S438
names: Similarity
messages: Belongs to the fabD family.

1302659:I858 RS14030
gene id: 1302659:I858_RS14030
uniprot id: A0A1B1S2B9
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1302659:I858 RS14060
gene id: 1302659:I858_RS14060
uniprot id: A0A1B1S2C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1302659:I858 RS05020
gene id: 1302659:I858_RS05020
uniprot id: A0A1B1RYI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1302659:I858 RS06240
gene id: 1302659:I858_RS06240
uniprot id: A0A1B1RXX8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS03685
gene id: 1302659:I858_RS03685
uniprot id: A0A1B1RZ60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1302659:I858 RS01470
gene id: 1302659:I858_RS01470
uniprot id: A0A1B1S0E9
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS02925
gene id: 1302659:I858_RS02925
uniprot id: A0A1B1RZK6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

1302659:I858 RS10445
gene id: 1302659:I858_RS10445
uniprot id: A0A1B1S4C9
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1302659:I858 RS04760
gene id: 1302659:I858_RS04760
uniprot id: A0A1B1RYM0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1302659:I858 RS10120
gene id: 1302659:I858_RS10120
uniprot id: A0A1B1S4M7
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.
messages: Cytoplasm

1302659:I858 RS00740
gene id: 1302659:I858_RS00740
uniprot id: A0A1B1S0R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1302659:I858 RS06605
gene id: 1302659:I858_RS06605
uniprot id: A0A1B1RXN5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS03845
gene id: 1302659:I858_RS03845
uniprot id: A0A1B1RZ25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS11445
gene id: 1302659:I858_RS11445
uniprot id: A0A1B1S3P7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1302659:I858 RS14315
gene id: 1302659:I858_RS14315
uniprot id: A0A1B1S273
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1302659:I858 RS10920
gene id: 1302659:I858_RS10920
uniprot id: A0A1B1S420
names: Similarity
messages: Belongs to the asp23 family.

1302659:I858 RS05555
gene id: 1302659:I858_RS05555
uniprot id: A0A1B1RY68
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1302659:I858 RS10980
gene id: 1302659:I858_RS10980
uniprot id: A0A1B1S462
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1302659:I858 RS07230
gene id: 1302659:I858_RS07230
uniprot id: A0A1B1RXC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1302659:I858 RS03045
gene id: 1302659:I858_RS03045
uniprot id: A0A1B1RZK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS15115
gene id: 1302659:I858_RS15115
uniprot id: A0A1B1S1Q0
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

1302659:I858 RS11850
gene id: 1302659:I858_RS11850
uniprot id: A0A1B1S3G9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1302659:I858 RS13710
gene id: 1302659:I858_RS13710
uniprot id: A0A1B1S2I8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1302659:I858 RS00085
gene id: 1302659:I858_RS00085
uniprot id: A0A1B1S122
names: Similarity
messages: Belongs to the DCK/DGK family.

1302659:I858 RS05755
gene id: 1302659:I858_RS05755
uniprot id: A0A1B1RY41
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1302659:I858 RS03165
gene id: 1302659:I858_RS03165
uniprot id: A0A1B1RZH2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1302659:I858 RS05075
gene id: 1302659:I858_RS05075
uniprot id: A0A1B1RYH9
names: Similarity
messages: Belongs to the UPF0342 family.

1302659:I858 RS13460
gene id: 1302659:I858_RS13460
uniprot id: A0A1B1S2P0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1302659:I858 RS07695
gene id: 1302659:I858_RS07695
uniprot id: A0A1B1RX33
names: Cofactor
messages: Binds 1 FAD per subunit.

1302659:I858 RS16265
gene id: 1302659:I858_RS16265
uniprot id: A0A1B1S141
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1302659:I858 RS01260
gene id: 1302659:I858_RS01260
uniprot id: A0A1B1S0F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS08935
gene id: 1302659:I858_RS08935
uniprot id: A0A1B1S567
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS10770
gene id: 1302659:I858_RS10770
uniprot id: A0A1B1S446
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1302659:I858 RS00675
gene id: 1302659:I858_RS00675
uniprot id: A0A1B1S0U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1302659:I858 RS01515
gene id: 1302659:I858_RS01515
uniprot id: A0A1B1S0D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1302659:I858 RS01075
gene id: 1302659:I858_RS01075
uniprot id: A0A1B1S0L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1302659:I858 RS00620
gene id: 1302659:I858_RS00620
uniprot id: A0A1B1S0V5
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS00595
gene id: 1302659:I858_RS00595
uniprot id: A0A1B1S0U0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS13370
gene id: 1302659:I858_RS13370
uniprot id: A0A1B1S2Q5
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1302659:I858 RS05550
gene id: 1302659:I858_RS05550
uniprot id: A0A1B1RY81
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1302659:I858 RS00790
gene id: 1302659:I858_RS00790
uniprot id: A0A1B1S0Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1302659:I858 RS13000
gene id: 1302659:I858_RS13000
uniprot id: A0A1B1S313
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1302659:I858 RS08230
gene id: 1302659:I858_RS08230
uniprot id: A0A1B1S5J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacteriophage holin family. Cp-1 holin subfamily.
messages: Membrane

1302659:I858 RS05770
gene id: 1302659:I858_RS05770
uniprot id: A0A1B1RY49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1302659:I858 RS08595
gene id: 1302659:I858_RS08595
uniprot id: A0A1B1S5C7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1302659:I858 RS05955
gene id: 1302659:I858_RS05955
uniprot id: A0A1B1RY14
names: Similarity
messages: Belongs to the Dps family.

1302659:I858 RS02765
gene id: 1302659:I858_RS02765
uniprot id: A0A1B1RZM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1302659:I858 RS04290
gene id: 1302659:I858_RS04290
uniprot id: A0A1B1RYV6
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS13075
gene id: 1302659:I858_RS13075
uniprot id: A0A1B1S2W3
names: Similarity
messages: Belongs to the peptidase S8 family.

1302659:I858 RS00760
gene id: 1302659:I858_RS00760
uniprot id: A0A1B1S0R6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1302659:I858 RS10740
gene id: 1302659:I858_RS10740
uniprot id: A0A1B1S463
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1302659:I858 RS00680
gene id: 1302659:I858_RS00680
uniprot id: A0A1B1S0S4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1302659:I858 RS06805
gene id: 1302659:I858_RS06805
uniprot id: A0A1B1RXL1
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1302659:I858 RS05405
gene id: 1302659:I858_RS05405
uniprot id: A0A1B1RYA6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1302659:I858 RS00330
gene id: 1302659:I858_RS00330
uniprot id: A0A1B1S0Z7
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1302659:I858 RS12510
gene id: 1302659:I858_RS12510
uniprot id: A0A1B1S367
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1302659:I858 RS02365
gene id: 1302659:I858_RS02365
uniprot id: A0A1B1RZV3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1302659:I858 RS00950
gene id: 1302659:I858_RS00950
uniprot id: A0A1B1S0R0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

1302659:I858 RS05365
gene id: 1302659:I858_RS05365
uniprot id: A0A1B1RYA9
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1302659:I858 RS02375
gene id: 1302659:I858_RS02375
uniprot id: A0A1B1RZX5
names: Similarity
messages: Belongs to the UPF0312 family.

1302659:I858 RS15160
gene id: 1302659:I858_RS15160
uniprot id: A0A1B1S1U0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1302659:I858 RS13905
gene id: 1302659:I858_RS13905
uniprot id: A0A1B1S2F1
names: Similarity
messages: Belongs to the PspA/IM30 family.

1302659:I858 RS08165
gene id: 1302659:I858_RS08165
uniprot id: A0A1B1S5L5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
messages: Monomer.

1302659:I858 RS03985
gene id: 1302659:I858_RS03985
uniprot id: A0A1B1RYZ6
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

1302659:I858 RS14830
gene id: 1302659:I858_RS14830
uniprot id: A0A1B1S1X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS08795
gene id: 1302659:I858_RS08795
uniprot id: A0A1B1S596
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1302659:I858 RS10750
gene id: 1302659:I858_RS10750
uniprot id: A0A1B1S472
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS15725
gene id: 1302659:I858_RS15725
uniprot id: A0A1B1S1E1
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1302659:I858 RS13510
gene id: 1302659:I858_RS13510
uniprot id: A0A1B1S2M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1302659:I858 RS04485
gene id: 1302659:I858_RS04485
uniprot id: A0A1B1RYQ8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1302659:I858 RS15245
gene id: 1302659:I858_RS15245
uniprot id: A0A1B1S1P4
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

1302659:I858 RS14010
gene id: 1302659:I858_RS14010
uniprot id: A0A1B1S2D3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1302659:I858 RS03960
gene id: 1302659:I858_RS03960
uniprot id: A0A1B1RZ08
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1302659:I858 RS02470
gene id: 1302659:I858_RS02470
uniprot id: A0A1B1RZU0
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1302659:I858 RS00995
gene id: 1302659:I858_RS00995
uniprot id: A0A1B1S0L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1302659:I858 RS11740
gene id: 1302659:I858_RS11740
uniprot id: A0A1B1S3R0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1302659:I858 RS05675
gene id: 1302659:I858_RS05675
uniprot id: A0A1B1RY56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS11305
gene id: 1302659:I858_RS11305
uniprot id: A0A1B1S3U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1302659:I858 RS00600
gene id: 1302659:I858_RS00600
uniprot id: A0A1B1S0X2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1302659:I858 RS14145
gene id: 1302659:I858_RS14145
uniprot id: A0A1B1S296
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS09715
gene id: 1302659:I858_RS09715
uniprot id: A0A1B1S4P9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1302659:I858 RS10985
gene id: 1302659:I858_RS10985
uniprot id: A0A1B1S419
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1302659:I858 RS10370
gene id: 1302659:I858_RS10370
uniprot id: A0A1B1S4I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS10570
gene id: 1302659:I858_RS10570
uniprot id: A0A1B1S486
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

1302659:I858 RS09300
gene id: 1302659:I858_RS09300
uniprot id: A0A1B1S537
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1302659:I858 RS02265
gene id: 1302659:I858_RS02265
uniprot id: A0A1B1RZX7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1302659:I858 RS10905
gene id: 1302659:I858_RS10905
uniprot id: A0A1B1S441
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1302659:I858 RS05500
gene id: 1302659:I858_RS05500
uniprot id: A0A1B1RY91
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1302659:I858 RS06715
gene id: 1302659:I858_RS06715
uniprot id: A0A1B1RXM4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1302659:I858 RS14265
gene id: 1302659:I858_RS14265
uniprot id: A0A1B1S284
names: Similarity
messages: Belongs to the class-I fumarase family.

1302659:I858 RS07345
gene id: 1302659:I858_RS07345
uniprot id: A0A1B1RX89
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1302659:I858 RS06360
gene id: 1302659:I858_RS06360
uniprot id: A0A1B1RXU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1302659:I858 RS02990
gene id: 1302659:I858_RS02990
uniprot id: A0A1B1RZK9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1302659:I858 RS12215
gene id: 1302659:I858_RS12215
uniprot id: A0A1B1S3H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

1302659:I858 RS06750
gene id: 1302659:I858_RS06750
uniprot id: A0A1B1RXM0
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1302659:I858 RS07765
gene id: 1302659:I858_RS07765
uniprot id: A0A1B1RX16
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1302659:I858 RS09440
gene id: 1302659:I858_RS09440
uniprot id: A0A1B1S4W0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1302659:I858 RS08555
gene id: 1302659:I858_RS08555
uniprot id: A0A1B1S5D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1302659:I858 RS03300
gene id: 1302659:I858_RS03300
uniprot id: A0A1B1RZF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1302659:I858 RS05260
gene id: 1302659:I858_RS05260
uniprot id: A0A1B1RYC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1302659:I858 RS04240
gene id: 1302659:I858_RS04240
uniprot id: A0A1B1RYW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1302659:I858 RS04780
gene id: 1302659:I858_RS04780
uniprot id: A0A1B1RYK0
names: Similarity
messages: Belongs to the Fur family.

1302659:I858 RS11930
gene id: 1302659:I858_RS11930
uniprot id: A0A1B1S3I8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of AddA and AddB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.

1302659:I858 RS10640
gene id: 1302659:I858_RS10640
uniprot id: A0A1B1S481
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1302659:I858 RS00080
gene id: 1302659:I858_RS00080
uniprot id: A0A1B1S132
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1302659:I858 RS06980
gene id: 1302659:I858_RS06980
uniprot id: A0A1B1RXH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1302659:I858 RS16205
gene id: 1302659:I858_RS16205
uniprot id: A0A1B1S164
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1302659:I858 RS07060
gene id: 1302659:I858_RS07060
uniprot id: A0A1B1RXF6
names: Similarity
messages: Belongs to the RecJ family.

1302659:I858 RS06380
gene id: 1302659:I858_RS06380
uniprot id: A0A1B1RXT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EzrA family.
messages: Cell membrane
messages: Membrane
messages: Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization.

1302659:I858 RS10160
gene id: 1302659:I858_RS10160
uniprot id: A0A1B1S4H4
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1302659:I858 RS13375
gene id: 1302659:I858_RS13375
uniprot id: A0A1B1S2P2
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1302659:I858 RS15020
gene id: 1302659:I858_RS15020
uniprot id: A0A1B1S1T4
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1302659:I858 RS02740
gene id: 1302659:I858_RS02740
uniprot id: A0A1B1RZM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1302659:I858 RS03725
gene id: 1302659:I858_RS03725
uniprot id: A0A1B1RZ59
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1302659:I858 RS06810
gene id: 1302659:I858_RS06810
uniprot id: A0A1B1RXK8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1302659:I858 RS01160
gene id: 1302659:I858_RS01160
uniprot id: A0A1B1S0G5
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1302659:I858 RS01020
gene id: 1302659:I858_RS01020
uniprot id: A0A1B1S0N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1302659:I858 RS10900
gene id: 1302659:I858_RS10900
uniprot id: A0A1B1S425
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1302659:I858 RS12935
gene id: 1302659:I858_RS12935
uniprot id: A0A1B1S2Z3
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1302659:I858 RS14310
gene id: 1302659:I858_RS14310
uniprot id: A0A1B1S271
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS13620
gene id: 1302659:I858_RS13620
uniprot id: A0A1B1S2K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1302659:I858 RS05410
gene id: 1302659:I858_RS05410
uniprot id: A0A1B1RY86
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1302659:I858 RS09455
gene id: 1302659:I858_RS09455
uniprot id: A0A1B1S4W8
names: Similarity
messages: Belongs to the UPF0346 family.

1302659:I858 RS10190
gene id: 1302659:I858_RS10190
uniprot id: A0A1B1S4H5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS01595
gene id: 1302659:I858_RS01595
uniprot id: A0A1B1S097
names: Similarity
messages: Belongs to the peptidase C40 family.

1302659:I858 RS05275
gene id: 1302659:I858_RS05275
uniprot id: A0A1B1RYB0
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1302659:I858 RS15855
gene id: 1302659:I858_RS15855
uniprot id: A0A1B1S1F5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1302659:I858 RS12315
gene id: 1302659:I858_RS12315
uniprot id: A0A1B1S3F0
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS10990
gene id: 1302659:I858_RS10990
uniprot id: A0A1B1S3Z1
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

1302659:I858 RS04625
gene id: 1302659:I858_RS04625
uniprot id: A0A1B1RYP6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

1302659:I858 RS12500
gene id: 1302659:I858_RS12500
uniprot id: A0A1B1S375
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1302659:I858 RS10510
gene id: 1302659:I858_RS10510
uniprot id: A0A1B1S4A3
names: Similarity
messages: Belongs to the glutamine synthetase family.

1302659:I858 RS10580
gene id: 1302659:I858_RS10580
uniprot id: A0A1B1S499
names: Similarity
messages: Belongs to the CinA family.

1302659:I858 RS02930
gene id: 1302659:I858_RS02930
uniprot id: A0A1B1RZK3
names: Similarity
messages: Belongs to the UPF0309 family.

1302659:I858 RS00955
gene id: 1302659:I858_RS00955
uniprot id: A0A1B1S0K5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1302659:I858 RS13695
gene id: 1302659:I858_RS13695
uniprot id: A0A1B1S2J0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1302659:I858 RS09000
gene id: 1302659:I858_RS09000
uniprot id: A0A1B1S554
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1302659:I858 RS06090
gene id: 1302659:I858_RS06090
uniprot id: A0A1B1RXY5
names: Similarity
messages: Belongs to the PemK/MazF family.

1302659:I858 RS01105
gene id: 1302659:I858_RS01105
uniprot id: A0A1B1S0M8
names: Similarity
messages: Belongs to the FlgD family.

1302659:I858 RS13280
gene id: 1302659:I858_RS13280
uniprot id: A0A1B1S2S3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS11970
gene id: 1302659:I858_RS11970
uniprot id: A0A1B1S3H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

1302659:I858 RS10020
gene id: 1302659:I858_RS10020
uniprot id: A0A1B1S4Q1
names: Function
names: Similarity
messages: 3'-5' exonuclease.
messages: Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.

1302659:I858 RS01705
gene id: 1302659:I858_RS01705
uniprot id: A0A1B1S086
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1302659:I858 RS16285
gene id: 1302659:I858_RS16285
uniprot id: A0A1B1S142
names: Similarity
messages: Belongs to the ParB family.

1302659:I858 RS08145
gene id: 1302659:I858_RS08145
uniprot id: A0A1B1S5M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1302659:I858 RS08635
gene id: 1302659:I858_RS08635
uniprot id: A0A1B1S5B4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1302659:I858 RS04130
gene id: 1302659:I858_RS04130
uniprot id: A0A1B1RYY2
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

1302659:I858 RS04245
gene id: 1302659:I858_RS04245
uniprot id: A0A1B1RYV0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS11805
gene id: 1302659:I858_RS11805
uniprot id: A0A1B1S3J5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1302659:I858 RS01505
gene id: 1302659:I858_RS01505
uniprot id: A0A1B1S0E8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1302659:I858 RS00110
gene id: 1302659:I858_RS00110
uniprot id: A0A1B1S133
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1302659:I858 RS06885
gene id: 1302659:I858_RS06885
uniprot id: A0A1B1RXI2
names: Function
messages: Required for transformation and DNA binding.

1302659:I858 RS14825
gene id: 1302659:I858_RS14825
uniprot id: A0A1B1S1Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

1302659:I858 RS02290
gene id: 1302659:I858_RS02290
uniprot id: A0A1B1RZY3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1302659:I858 RS08590
gene id: 1302659:I858_RS08590
uniprot id: A0A1B1S5D7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1302659:I858 RS10680
gene id: 1302659:I858_RS10680
uniprot id: A0A1B1S480
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1302659:I858 RS01860
gene id: 1302659:I858_RS01860
uniprot id: A0A1B1S078
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1302659:I858 RS06210
gene id: 1302659:I858_RS06210
uniprot id: A0A1B1RXX3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1302659:I858 RS05930
gene id: 1302659:I858_RS05930
uniprot id: A0A1B1RY10
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

1302659:I858 RS02855
gene id: 1302659:I858_RS02855
uniprot id: A0A1B1RZN2
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1302659:I858 RS09405
gene id: 1302659:I858_RS09405
uniprot id: A0A1B1S4X8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Forms a 24-polypeptide structural core with octahedral symmetry. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

1302659:I858 RS07720
gene id: 1302659:I858_RS07720
uniprot id: A0A1B1RX29
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1302659:I858 RS12785
gene id: 1302659:I858_RS12785
uniprot id: A0A1B1S2Z4
names: Similarity
messages: Belongs to the PrpD family.

1302659:I858 RS11470
gene id: 1302659:I858_RS11470
uniprot id: A0A1B1S3T3
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS12275
gene id: 1302659:I858_RS12275
uniprot id: A0A1B1S392
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS12230
gene id: 1302659:I858_RS12230
uniprot id: A0A1B1S3C0
names: Subcellular Location Annotation
messages: Cell membrane

1302659:I858 RS14235
gene id: 1302659:I858_RS14235
uniprot id: A0A1B1S276
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS10880
gene id: 1302659:I858_RS10880
uniprot id: A0A1B1S479
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1302659:I858 RS06510
gene id: 1302659:I858_RS06510
uniprot id: A0A1B1RXR2
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

1302659:I858 RS04400
gene id: 1302659:I858_RS04400
uniprot id: A0A1B1RYP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1302659:I858 RS14225
gene id: 1302659:I858_RS14225
uniprot id: A0A1B1S282
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1302659:I858 RS07040
gene id: 1302659:I858_RS07040
uniprot id: A0A1B1RXF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1302659:I858 RS14880
gene id: 1302659:I858_RS14880
uniprot id: A0A1B1S1W0
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1302659:I858 RS14895
gene id: 1302659:I858_RS14895
uniprot id: A0A1B1S1V4
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1302659:I858 RS01205
gene id: 1302659:I858_RS01205
uniprot id: A0A1B1S0K8
names: Subcellular Location Annotation
messages: Cell membrane

1302659:I858 RS15960
gene id: 1302659:I858_RS15960
uniprot id: A0A1B1S1D6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1302659:I858 RS16290
gene id: 1302659:I858_RS16290
uniprot id: A0A1B1S146
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.

1302659:I858 RS04980
gene id: 1302659:I858_RS04980
uniprot id: A0A1B1RYH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Membrane

1302659:I858 RS00670
gene id: 1302659:I858_RS00670
uniprot id: A0A1B1S0U5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1302659:I858 RS10155
gene id: 1302659:I858_RS10155
uniprot id: A0A1B1S4I0
names: Similarity
names: Subunit
messages: Belongs to the MtrB family.
messages: Oligomer of 11 identical subunits arranged in doughnut-like structure.

1302659:I858 RS11170
gene id: 1302659:I858_RS11170
uniprot id: A0A1B1S3Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1302659:I858 RS04095
gene id: 1302659:I858_RS04095
uniprot id: A0A1B1RYX9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1302659:I858 RS08765
gene id: 1302659:I858_RS08765
uniprot id: A0A1B1S5A6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1302659:I858 RS13635
gene id: 1302659:I858_RS13635
uniprot id: A0A1B1S2J2
names: Similarity
messages: Belongs to the ThiD family.

1302659:I858 RS08750
gene id: 1302659:I858_RS08750
uniprot id: A0A1B1S599
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1302659:I858 RS05355
gene id: 1302659:I858_RS05355
uniprot id: A0A1B1RYA2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1302659:I858 RS11035
gene id: 1302659:I858_RS11035
uniprot id: A0A1B1S453
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1302659:I858 RS13610
gene id: 1302659:I858_RS13610
uniprot id: A0A1B1S2K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1302659:I858 RS06700
gene id: 1302659:I858_RS06700
uniprot id: A0A1B1RXN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

1302659:I858 RS04085
gene id: 1302659:I858_RS04085
uniprot id: A0A1B1RYX7
names: Similarity
messages: Belongs to the CapA family.

1302659:I858 RS04950
gene id: 1302659:I858_RS04950
uniprot id: A0A1B1RYJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

1302659:I858 RS03690
gene id: 1302659:I858_RS03690
uniprot id: A0A1B1RZ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1302659:I858 RS08890
gene id: 1302659:I858_RS08890
uniprot id: A0A1B1S572
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1302659:I858 RS11155
gene id: 1302659:I858_RS11155
uniprot id: A0A1B1S3X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1302659:I858 RS16075
gene id: 1302659:I858_RS16075
uniprot id: A0A1B1S174
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

1302659:I858 RS03955
gene id: 1302659:I858_RS03955
uniprot id: A0A1B1RZ09
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS04035
gene id: 1302659:I858_RS04035
uniprot id: A0A1B1RYY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS02385
gene id: 1302659:I858_RS02385
uniprot id: A0A1B1RZW5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1302659:I858 RS13575
gene id: 1302659:I858_RS13575
uniprot id: A0A1B1S2P5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1302659:I858 RS10705
gene id: 1302659:I858_RS10705
uniprot id: A0A1B1S468
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1302659:I858 RS13410
gene id: 1302659:I858_RS13410
uniprot id: A0A1B1S2P6
names: Similarity
messages: Belongs to the FBPase class 2 family.

1302659:I858 RS12505
gene id: 1302659:I858_RS12505
uniprot id: A0A1B1S371
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1302659:I858 RS11405
gene id: 1302659:I858_RS11405
uniprot id: A0A1B1S3S8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1302659:I858 RS01125
gene id: 1302659:I858_RS01125
uniprot id: A0A1B1S0K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

1302659:I858 RS02625
gene id: 1302659:I858_RS02625
uniprot id: A0A1B1RZR6
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

1302659:I858 RS14760
gene id: 1302659:I858_RS14760
uniprot id: A0A1B1S1X6
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1302659:I858 RS13465
gene id: 1302659:I858_RS13465
uniprot id: A0A1B1S2N6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1302659:I858 RS11145
gene id: 1302659:I858_RS11145
uniprot id: A0A1B1S3W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. DivIB subfamily.
messages: Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
messages: Cell membrane

1302659:I858 RS03675
gene id: 1302659:I858_RS03675
uniprot id: A0A1B1RZ62
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1302659:I858 RS06695
gene id: 1302659:I858_RS06695
uniprot id: A0A1B1RXN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1302659:I858 RS16020
gene id: 1302659:I858_RS16020
uniprot id: A0A1B1S180
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS04045
gene id: 1302659:I858_RS04045
uniprot id: A0A1B1RYY9
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS10615
gene id: 1302659:I858_RS10615
uniprot id: A0A1B1S482
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS05320
gene id: 1302659:I858_RS05320
uniprot id: A0A1B1RYD0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1302659:I858 RS07080
gene id: 1302659:I858_RS07080
uniprot id: A0A1B1RXF2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1302659:I858 RS10410
gene id: 1302659:I858_RS10410
uniprot id: A0A1B1S4C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS02910
gene id: 1302659:I858_RS02910
uniprot id: A0A1B1RZL9
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1302659:I858 RS02115
gene id: 1302659:I858_RS02115
uniprot id: A0A1B1S024
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1302659:I858 RS01855
gene id: 1302659:I858_RS01855
uniprot id: A0A1B1S059
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1302659:I858 RS03870
gene id: 1302659:I858_RS03870
uniprot id: A0A1B1RZ00
names: Similarity
messages: Belongs to the PspA/IM30 family.

1302659:I858 RS10785
gene id: 1302659:I858_RS10785
uniprot id: A0A1B1S434
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1302659:I858 RS00215
gene id: 1302659:I858_RS00215
uniprot id: A0A1B1S110
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1302659:I858 RS00480
gene id: 1302659:I858_RS00480
uniprot id: A0A1B1S0V9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1302659:I858 RS12460
gene id: 1302659:I858_RS12460
uniprot id: A0A1B1S377
names: Activity Regulation
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), including enzyme I, and histidine-containing protein (HPr) are required for the phosphorylation, which leads to the activation of the enzyme.

1302659:I858 RS05600
gene id: 1302659:I858_RS05600
uniprot id: A0A1B1RY71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1302659:I858 RS07990
gene id: 1302659:I858_RS07990
uniprot id: A0A1B1S5N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS04775
gene id: 1302659:I858_RS04775
uniprot id: A0A1B1RYL6
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1302659:I858 RS13840
gene id: 1302659:I858_RS13840
uniprot id: A0A1B1S2G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1302659:I858 RS10250
gene id: 1302659:I858_RS10250
uniprot id: A0A1B1S4G3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1302659:I858 RS14105
gene id: 1302659:I858_RS14105
uniprot id: A0A1B1S2A8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS14905
gene id: 1302659:I858_RS14905
uniprot id: A0A1B1S1Y9
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1302659:I858 RS05510
gene id: 1302659:I858_RS05510
uniprot id: A0A1B1RY94
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1302659:I858 RS00715
gene id: 1302659:I858_RS00715
uniprot id: A0A1B1S0T3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1302659:I858 RS05960
gene id: 1302659:I858_RS05960
uniprot id: A0A1B1RY38
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1302659:I858 RS12565
gene id: 1302659:I858_RS12565
uniprot id: A0A1B1S355
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1302659:I858 RS02070
gene id: 1302659:I858_RS02070
uniprot id: A0A1B1RZZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1302659:I858 RS05765
gene id: 1302659:I858_RS05765
uniprot id: A0A1B1RY20
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS06195
gene id: 1302659:I858_RS06195
uniprot id: A0A1B1RXX2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS04970
gene id: 1302659:I858_RS04970
uniprot id: A0A1B1RYJ8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1302659:I858 RS11660
gene id: 1302659:I858_RS11660
uniprot id: A0A1B1S3M8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1302659:I858 RS09935
gene id: 1302659:I858_RS09935
uniprot id: A0A1B1S4M6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

1302659:I858 RS08100
gene id: 1302659:I858_RS08100
uniprot id: A0A1B1S5P4
names: Similarity
messages: Belongs to the EamA transporter family.

1302659:I858 RS05420
gene id: 1302659:I858_RS05420
uniprot id: A0A1B1RY98
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1302659:I858 RS04390
gene id: 1302659:I858_RS04390
uniprot id: A0A1B1RYT5
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1302659:I858 RS10730
gene id: 1302659:I858_RS10730
uniprot id: A0A1B1S469
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

1302659:I858 RS12150
gene id: 1302659:I858_RS12150
uniprot id: A0A1B1S3E6
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1302659:I858 RS13680
gene id: 1302659:I858_RS13680
uniprot id: A0A1B1S2J4
names: Subcellular Location Annotation
messages: Cell membrane

1302659:I858 RS06615
gene id: 1302659:I858_RS06615
uniprot id: A0A1B1RXP6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1302659:I858 RS11280
gene id: 1302659:I858_RS11280
uniprot id: A0A1B1S3V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1302659:I858 RS07590
gene id: 1302659:I858_RS07590
uniprot id: A0A1B1RX52
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1302659:I858 RS06225
gene id: 1302659:I858_RS06225
uniprot id: A0A1B1RXW2
names: Function
names: Similarity
names: Subunit
messages: Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1302659:I858 RS15155
gene id: 1302659:I858_RS15155
uniprot id: A0A1B1S1Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS14680
gene id: 1302659:I858_RS14680
uniprot id: A0A1B1S204
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS09460
gene id: 1302659:I858_RS09460
uniprot id: A0A1B1S4U7
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS09955
gene id: 1302659:I858_RS09955
uniprot id: A0A1B1S4L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GpsB family.
messages: Cytoplasm
messages: Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
messages: Forms polymers through the coiled coil domains. Interacts with PBP1, MreC and EzrA.

1302659:I858 RS08585
gene id: 1302659:I858_RS08585
uniprot id: A0A1B1S5C5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1302659:I858 RS10300
gene id: 1302659:I858_RS10300
uniprot id: A0A1B1S4F2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1302659:I858 RS13385
gene id: 1302659:I858_RS13385
uniprot id: A0A1B1S2Q3
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1302659:I858 RS10790
gene id: 1302659:I858_RS10790
uniprot id: A0A1B1S452
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1302659:I858 RS07935
gene id: 1302659:I858_RS07935
uniprot id: A0A1B1S5Q0
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

1302659:I858 RS08150
gene id: 1302659:I858_RS08150
uniprot id: A0A1B1S5L6
names: Similarity
messages: Belongs to the HesB/IscA family.

1302659:I858 RS15910
gene id: 1302659:I858_RS15910
uniprot id: A0A1B1S1E6
names: Similarity
messages: Belongs to the FGGY kinase family.

1302659:I858 RS16085
gene id: 1302659:I858_RS16085
uniprot id: A0A1B1S166
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

1302659:I858 RS14995
gene id: 1302659:I858_RS14995
uniprot id: A0A1B1S1T3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1302659:I858 RS05535
gene id: 1302659:I858_RS05535
uniprot id: A0A1B1RY97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1302659:I858 RS02750
gene id: 1302659:I858_RS02750
uniprot id: A0A1B1RZQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

1302659:I858 RS11085
gene id: 1302659:I858_RS11085
uniprot id: A0A1B1S443
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1302659:I858 RS00880
gene id: 1302659:I858_RS00880
uniprot id: A0A1B1S0P4
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

1302659:I858 RS08665
gene id: 1302659:I858_RS08665
uniprot id: A0A1B1S5B9
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1302659:I858 RS04410
gene id: 1302659:I858_RS04410
uniprot id: A0A1B1RYT2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1302659:I858 RS08735
gene id: 1302659:I858_RS08735
uniprot id: A0A1B1S594
names: Similarity
messages: Belongs to the asp23 family.

1302659:I858 RS11310
gene id: 1302659:I858_RS11310
uniprot id: A0A1B1S3V4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1302659:I858 RS07920
gene id: 1302659:I858_RS07920
uniprot id: A0A1B1S5S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1302659:I858 RS00565
gene id: 1302659:I858_RS00565
uniprot id: A0A1B1S0W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1302659:I858 RS16255
gene id: 1302659:I858_RS16255
uniprot id: A0A1B1S168
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1302659:I858 RS10030
gene id: 1302659:I858_RS10030
uniprot id: A0A1B1S4I6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1302659:I858 RS03265
gene id: 1302659:I858_RS03265
uniprot id: A0A1B1RZE9
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1302659:I858 RS06230
gene id: 1302659:I858_RS06230
uniprot id: A0A1B1RXY1
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1302659:I858 RS07395
gene id: 1302659:I858_RS07395
uniprot id: A0A1B1RX78
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1302659:I858 RS13125
gene id: 1302659:I858_RS13125
uniprot id: A0A1B1S2V4
names: Similarity
messages: Belongs to the acyltransferase 3 family.

1302659:I858 RS00630
gene id: 1302659:I858_RS00630
uniprot id: A0A1B1S0T4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1302659:I858 RS10845
gene id: 1302659:I858_RS10845
uniprot id: A0A1B1S435
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1302659:I858 RS04185
gene id: 1302659:I858_RS04185
uniprot id: A0A1B1RYV7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1302659:I858 RS13515
gene id: 1302659:I858_RS13515
uniprot id: A0A1B1S2N0
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1302659:I858 RS14640
gene id: 1302659:I858_RS14640
uniprot id: A0A1B1S207
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

1302659:I858 RS08045
gene id: 1302659:I858_RS08045
uniprot id: A0A1B1S5Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1302659:I858 RS06590
gene id: 1302659:I858_RS06590
uniprot id: A0A1B1RXQ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1302659:I858 RS12070
gene id: 1302659:I858_RS12070
uniprot id: A0A1B1S3F5
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1302659:I858 RS07385
gene id: 1302659:I858_RS07385
uniprot id: A0A1B1RX95
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1302659:I858 RS00010
gene id: 1302659:I858_RS00010
uniprot id: A0A1B1S107
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1302659:I858 RS04110
gene id: 1302659:I858_RS04110
uniprot id: A0A1B1RYY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS07140
gene id: 1302659:I858_RS07140
uniprot id: A0A1B1RXD4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1302659:I858 RS14815
gene id: 1302659:I858_RS14815
uniprot id: A0A1B1S1X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS00515
gene id: 1302659:I858_RS00515
uniprot id: A0A1B1S0X3
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1302659:I858 RS04315
gene id: 1302659:I858_RS04315
uniprot id: A0A1B1RYT6
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1302659:I858 RS14910
gene id: 1302659:I858_RS14910
uniprot id: A0A1B1S1U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS08710
gene id: 1302659:I858_RS08710
uniprot id: A0A1B1S5B6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1302659:I858 RS15920
gene id: 1302659:I858_RS15920
uniprot id: A0A1B1S1A2
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1302659:I858 RS01225
gene id: 1302659:I858_RS01225
uniprot id: A0A1B1S0I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS05630
gene id: 1302659:I858_RS05630
uniprot id: A0A1B1RY48
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1302659:I858 RS02915
gene id: 1302659:I858_RS02915
uniprot id: A0A1B1RZN3
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS09590
gene id: 1302659:I858_RS09590
uniprot id: A0A1B1S4T5
names: Similarity
messages: Belongs to the peptidase S66 family.

1302659:I858 RS04730
gene id: 1302659:I858_RS04730
uniprot id: A0A1B1RYL0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1302659:I858 RS05235
gene id: 1302659:I858_RS05235
uniprot id: A0A1B1RYC4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1302659:I858 RS04735
gene id: 1302659:I858_RS04735
uniprot id: A0A1B1RYK9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1302659:I858 RS07380
gene id: 1302659:I858_RS07380
uniprot id: A0A1B1RX91
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1302659:I858 RS04250
gene id: 1302659:I858_RS04250
uniprot id: A0A1B1RYW5
names: Similarity
messages: Belongs to the transpeptidase family.

1302659:I858 RS11070
gene id: 1302659:I858_RS11070
uniprot id: A0A1B1S408
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1302659:I858 RS08605
gene id: 1302659:I858_RS08605
uniprot id: A0A1B1S5C2
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1302659:I858 RS14765
gene id: 1302659:I858_RS14765
uniprot id: A0A1B1S1Y1
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1302659:I858 RS15090
gene id: 1302659:I858_RS15090
uniprot id: A0A1B1S1S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1302659:I858 RS03900
gene id: 1302659:I858_RS03900
uniprot id: A0A1B1RZ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

1302659:I858 RS03115
gene id: 1302659:I858_RS03115
uniprot id: A0A1B1RZH8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1302659:I858 RS01485
gene id: 1302659:I858_RS01485
uniprot id: A0A1B1S0C1
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1302659:I858 RS00660
gene id: 1302659:I858_RS00660
uniprot id: A0A1B1S0T6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1302659:I858 RS11625
gene id: 1302659:I858_RS11625
uniprot id: A0A1B1S3N6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS03065
gene id: 1302659:I858_RS03065
uniprot id: A0A1B1RZI8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1302659:I858 RS06675
gene id: 1302659:I858_RS06675
uniprot id: A0A1B1RXM8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family. RnhC subfamily.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1302659:I858 RS01055
gene id: 1302659:I858_RS01055
uniprot id: A0A1B1S0N7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1302659:I858 RS10135
gene id: 1302659:I858_RS10135
uniprot id: A0A1B1S4H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1302659:I858 RS13350
gene id: 1302659:I858_RS13350
uniprot id: A0A1B1S2Q8
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1302659:I858 RS12925
gene id: 1302659:I858_RS12925
uniprot id: A0A1B1S2Y8
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1302659:I858 RS15665
gene id: 1302659:I858_RS15665
uniprot id: A0A1B1S1I3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1302659:I858 RS11335
gene id: 1302659:I858_RS11335
uniprot id: A0A1B1S3Y9
names: Similarity
messages: Belongs to the UPF0358 family.

1302659:I858 RS10760
gene id: 1302659:I858_RS10760
uniprot id: A0A1B1S465
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1302659:I858 RS13685
gene id: 1302659:I858_RS13685
uniprot id: A0A1B1S2I2
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1302659:I858 RS01090
gene id: 1302659:I858_RS01090
uniprot id: A0A1B1S0L1
names: Subcellular Location Annotation
messages: Cytoplasm

1302659:I858 RS13820
gene id: 1302659:I858_RS13820
uniprot id: A0A1B1S2G4
names: Similarity
messages: Belongs to the EamA transporter family.

1302659:I858 RS01200
gene id: 1302659:I858_RS01200
uniprot id: A0A1B1S0I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS04140
gene id: 1302659:I858_RS04140
uniprot id: A0A1B1RYY7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1302659:I858 RS06830
gene id: 1302659:I858_RS06830
uniprot id: A0A1B1RXJ8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1302659:I858 RS05745
gene id: 1302659:I858_RS05745
uniprot id: A0A1B1RY53
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. RocA subfamily.

1302659:I858 RS05345
gene id: 1302659:I858_RS05345
uniprot id: A0A1B1RYC3
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1302659:I858 RS11115
gene id: 1302659:I858_RS11115
uniprot id: A0A1B1S3Z3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1302659:I858 RS09320
gene id: 1302659:I858_RS09320
uniprot id: A0A1B1S505
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1302659:I858 RS08945
gene id: 1302659:I858_RS08945
uniprot id: A0A1B1S561
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1302659:I858 RS13145
gene id: 1302659:I858_RS13145
uniprot id: A0A1B1S2V1
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

1302659:I858 RS13715
gene id: 1302659:I858_RS13715
uniprot id: A0A1B1S2J1
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. YrrT family.
messages: Could be a S-adenosyl-L-methionine-dependent methyltransferase.

1302659:I858 RS10080
gene id: 1302659:I858_RS10080
uniprot id: A0A1B1S4H7
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS10345
gene id: 1302659:I858_RS10345
uniprot id: A0A1B1S4E9
names: Similarity
messages: Belongs to the Fur family.

1302659:I858 RS10000
gene id: 1302659:I858_RS10000
uniprot id: A0A1B1S4L1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1302659:I858 RS15310
gene id: 1302659:I858_RS15310
uniprot id: A0A1B1S1M6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS12280
gene id: 1302659:I858_RS12280
uniprot id: A0A1B1S3B0
names: Cofactor
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

1302659:I858 RS14615
gene id: 1302659:I858_RS14615
uniprot id: A0A1B1S208
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS05375
gene id: 1302659:I858_RS05375
uniprot id: A0A1B1RY92
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1302659:I858 RS07595
gene id: 1302659:I858_RS07595
uniprot id: A0A1B1RX54
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1302659:I858 RS09485
gene id: 1302659:I858_RS09485
uniprot id: A0A1B1S4V5
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1302659:I858 RS13475
gene id: 1302659:I858_RS13475
uniprot id: A0A1B1S2N4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1302659:I858 RS03895
gene id: 1302659:I858_RS03895
uniprot id: A0A1B1RZ15
names: Subcellular Location Annotation
messages: Cytoplasm

1302659:I858 RS14720
gene id: 1302659:I858_RS14720
uniprot id: A0A1B1S1Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS11410
gene id: 1302659:I858_RS11410
uniprot id: A0A1B1S3T2
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1302659:I858 RS02415
gene id: 1302659:I858_RS02415
uniprot id: A0A1B1RZU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1302659:I858 RS03905
gene id: 1302659:I858_RS03905
uniprot id: A0A1B1RZ20
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1302659:I858 RS06640
gene id: 1302659:I858_RS06640
uniprot id: A0A1B1RXP4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1302659:I858 RS08010
gene id: 1302659:I858_RS08010
uniprot id: A0A1B1S5P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS11540
gene id: 1302659:I858_RS11540
uniprot id: A0A1B1S3Q4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1302659:I858 RS00440
gene id: 1302659:I858_RS00440
uniprot id: A0A1B1S102
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.

1302659:I858 RS10955
gene id: 1302659:I858_RS10955
uniprot id: A0A1B1S431
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1302659:I858 RS00230
gene id: 1302659:I858_RS00230
uniprot id: A0A1B1S104
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

1302659:I858 RS03715
gene id: 1302659:I858_RS03715
uniprot id: A0A1B1RZ28
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1302659:I858 RS12045
gene id: 1302659:I858_RS12045
uniprot id: A0A1B1S3F8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system DegS/DegU, which plays an important role in the transition growth phase.

1302659:I858 RS00450
gene id: 1302659:I858_RS00450
uniprot id: A0A1B1S0X6
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1302659:I858 RS01380
gene id: 1302659:I858_RS01380
uniprot id: A0A1B1S0H2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1302659:I858 RS00115
gene id: 1302659:I858_RS00115
uniprot id: A0A1B1S134
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1302659:I858 RS08090
gene id: 1302659:I858_RS08090
uniprot id: A0A1B1S5P1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1302659:I858 RS14045
gene id: 1302659:I858_RS14045
uniprot id: A0A1B1S2B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

1302659:I858 RS08650
gene id: 1302659:I858_RS08650
uniprot id: A0A1B1S5C4
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1302659:I858 RS04490
gene id: 1302659:I858_RS04490
uniprot id: A0A1B1RYR1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1302659:I858 RS03565
gene id: 1302659:I858_RS03565
uniprot id: A0A1B1RZA0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1302659:I858 RS07755
gene id: 1302659:I858_RS07755
uniprot id: A0A1B1RX22
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1302659:I858 RS07075
gene id: 1302659:I858_RS07075
uniprot id: A0A1B1RXE7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1302659:I858 RS00710
gene id: 1302659:I858_RS00710
uniprot id: A0A1B1S0S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1302659:I858 RS05025
gene id: 1302659:I858_RS05025
uniprot id: A0A1B1RYI5
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS03735
gene id: 1302659:I858_RS03735
uniprot id: A0A1B1RZ66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS08895
gene id: 1302659:I858_RS08895
uniprot id: A0A1B1S575
names: Similarity
messages: Belongs to the transpeptidase family.

1302659:I858 RS10975
gene id: 1302659:I858_RS10975
uniprot id: A0A1B1S414
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS05915
gene id: 1302659:I858_RS05915
uniprot id: A0A1B1RY22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

1302659:I858 RS14215
gene id: 1302659:I858_RS14215
uniprot id: A0A1B1S294
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1302659:I858 RS08970
gene id: 1302659:I858_RS08970
uniprot id: A0A1B1S551
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS00020
gene id: 1302659:I858_RS00020
uniprot id: A0A1B1S126
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1302659:I858 RS02240
gene id: 1302659:I858_RS02240
uniprot id: A0A1B1RZY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1302659:I858 RS05570
gene id: 1302659:I858_RS05570
uniprot id: A0A1B1RY54
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1302659:I858 RS11120
gene id: 1302659:I858_RS11120
uniprot id: A0A1B1S400
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1302659:I858 RS04460
gene id: 1302659:I858_RS04460
uniprot id: A0A1B1RYS2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GGGP/HepGP synthase family. Group I subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.

1302659:I858 RS04680
gene id: 1302659:I858_RS04680
uniprot id: A0A1B1RYL7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1302659:I858 RS12580
gene id: 1302659:I858_RS12580
uniprot id: A0A1B1S336
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS11715
gene id: 1302659:I858_RS11715
uniprot id: A0A1B1S3L8
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. YjcG family.

1302659:I858 RS00895
gene id: 1302659:I858_RS00895
uniprot id: A0A1B1S0N9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1302659:I858 RS14685
gene id: 1302659:I858_RS14685
uniprot id: A0A1B1S1Z8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1302659:I858 RS04905
gene id: 1302659:I858_RS04905
uniprot id: A0A1B1RYK7
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS01710
gene id: 1302659:I858_RS01710
uniprot id: A0A1B1S0A5
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

1302659:I858 RS01500
gene id: 1302659:I858_RS01500
uniprot id: A0A1B1S0C4
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

1302659:I858 RS11290
gene id: 1302659:I858_RS11290
uniprot id: A0A1B1S3V8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1302659:I858 RS06405
gene id: 1302659:I858_RS06405
uniprot id: A0A1B1RXS8
names: Similarity
messages: Belongs to the peptidase S49 family.

1302659:I858 RS10800
gene id: 1302659:I858_RS10800
uniprot id: A0A1B1S461
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1302659:I858 RS06285
gene id: 1302659:I858_RS06285
uniprot id: A0A1B1RXW0
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

1302659:I858 RS03295
gene id: 1302659:I858_RS03295
uniprot id: A0A1B1RZD1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1302659:I858 RS10275
gene id: 1302659:I858_RS10275
uniprot id: A0A1B1S4F4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1302659:I858 RS01920
gene id: 1302659:I858_RS01920
uniprot id: A0A1B1S051
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1302659:I858 RS01135
gene id: 1302659:I858_RS01135
uniprot id: A0A1B1S0J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1302659:I858 RS01435
gene id: 1302659:I858_RS01435
uniprot id: A0A1B1S0D1
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1302659:I858 RS07025
gene id: 1302659:I858_RS07025
uniprot id: A0A1B1RXG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1302659:I858 RS04990
gene id: 1302659:I858_RS04990
uniprot id: A0A1B1RYH7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1302659:I858 RS11165
gene id: 1302659:I858_RS11165
uniprot id: A0A1B1S3Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell membrane
messages: Essential cell division protein.
messages: Membrane

1302659:I858 RS06560
gene id: 1302659:I858_RS06560
uniprot id: A0A1B1RXQ2
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1302659:I858 RS11475
gene id: 1302659:I858_RS11475
uniprot id: A0A1B1S3R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS10715
gene id: 1302659:I858_RS10715
uniprot id: A0A1B1S459
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1302659:I858 RS05185
gene id: 1302659:I858_RS05185
uniprot id: A0A1B1RYD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1302659:I858 RS13330
gene id: 1302659:I858_RS13330
uniprot id: A0A1B1S2R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1302659:I858 RS08200
gene id: 1302659:I858_RS08200
uniprot id: A0A1B1S5K6
names: Similarity
messages: Belongs to the SCO1/2 family.

1302659:I858 RS07390
gene id: 1302659:I858_RS07390
uniprot id: A0A1B1RX94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1302659:I858 RS12490
gene id: 1302659:I858_RS12490
uniprot id: A0A1B1S369
names: Similarity
messages: Belongs to the CpsD/CapB family.

1302659:I858 RS08645
gene id: 1302659:I858_RS08645
uniprot id: A0A1B1S5C0
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

1302659:I858 RS12240
gene id: 1302659:I858_RS12240
uniprot id: A0A1B1S3B5
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1302659:I858 RS05620
gene id: 1302659:I858_RS05620
uniprot id: A0A1B1RY70
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.

1302659:I858 RS02610
gene id: 1302659:I858_RS02610
uniprot id: A0A1B1RZQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1302659:I858 RS13085
gene id: 1302659:I858_RS13085
uniprot id: A0A1B1S2W0
names: Similarity
messages: Belongs to the peptidase S8 family.

1302659:I858 RS01680
gene id: 1302659:I858_RS01680
uniprot id: A0A1B1S0B3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1302659:I858 RS13380
gene id: 1302659:I858_RS13380
uniprot id: A0A1B1S2Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1302659:I858 RS11845
gene id: 1302659:I858_RS11845
uniprot id: A0A1B1S3J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS04145
gene id: 1302659:I858_RS04145
uniprot id: A0A1B1RYW6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1302659:I858 RS01645
gene id: 1302659:I858_RS01645
uniprot id: A0A1B1S088
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1302659:I858 RS00745
gene id: 1302659:I858_RS00745
uniprot id: A0A1B1S0Q6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1302659:I858 RS14535
gene id: 1302659:I858_RS14535
uniprot id: A0A1B1S222
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1302659:I858 RS12440
gene id: 1302659:I858_RS12440
uniprot id: A0A1B1S380
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS05540
gene id: 1302659:I858_RS05540
uniprot id: A0A1B1RY63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1302659:I858 RS03225
gene id: 1302659:I858_RS03225
uniprot id: A0A1B1RZH0
names: Similarity
messages: Belongs to the UPF0751 family.

1302659:I858 RS01280
gene id: 1302659:I858_RS01280
uniprot id: A0A1B1S0J2
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS03815
gene id: 1302659:I858_RS03815
uniprot id: A0A1B1RZ06
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

1302659:I858 RS10645
gene id: 1302659:I858_RS10645
uniprot id: A0A1B1S477
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1302659:I858 RS08885
gene id: 1302659:I858_RS08885
uniprot id: A0A1B1S574
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1302659:I858 RS06740
gene id: 1302659:I858_RS06740
uniprot id: A0A1B1RXM9
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1302659:I858 RS13365
gene id: 1302659:I858_RS13365
uniprot id: A0A1B1S2T7
names: Similarity
messages: Belongs to the UPF0340 family.

1302659:I858 RS03465
gene id: 1302659:I858_RS03465
uniprot id: A0A1B1RZB9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1302659:I858 RS13360
gene id: 1302659:I858_RS13360
uniprot id: A0A1B1S2Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1302659:I858 RS07150
gene id: 1302659:I858_RS07150
uniprot id: A0A1B1RXE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1302659:I858 RS02605
gene id: 1302659:I858_RS02605
uniprot id: A0A1B1RZP8
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS00305
gene id: 1302659:I858_RS00305
uniprot id: A0A1B1S111
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1302659:I858 RS04560
gene id: 1302659:I858_RS04560
uniprot id: A0A1B1RYR0
names: Similarity
messages: Belongs to the peptidase M29 family.

1302659:I858 RS01955
gene id: 1302659:I858_RS01955
uniprot id: A0A1B1S039
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1302659:I858 RS16160
gene id: 1302659:I858_RS16160
uniprot id: A0A1B1S177
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1302659:I858 RS01475
gene id: 1302659:I858_RS01475
uniprot id: A0A1B1S0E0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1302659:I858 RS00785
gene id: 1302659:I858_RS00785
uniprot id: A0A1B1S0Q9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS00510
gene id: 1302659:I858_RS00510
uniprot id: A0A1B1S0W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1302659:I858 RS06620
gene id: 1302659:I858_RS06620
uniprot id: A0A1B1RXN9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1302659:I858 RS01540
gene id: 1302659:I858_RS01540
uniprot id: A0A1B1S0B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS02540
gene id: 1302659:I858_RS02540
uniprot id: A0A1B1RZS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1302659:I858 RS11910
gene id: 1302659:I858_RS11910
uniprot id: A0A1B1S3H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0344 family.
messages: Cell membrane

1302659:I858 RS07940
gene id: 1302659:I858_RS07940
uniprot id: A0A1B1S5Q9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1302659:I858 RS06575
gene id: 1302659:I858_RS06575
uniprot id: A0A1B1RXN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1302659:I858 RS05325
gene id: 1302659:I858_RS05325
uniprot id: A0A1B1RYA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1302659:I858 RS11150
gene id: 1302659:I858_RS11150
uniprot id: A0A1B1S3X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1302659:I858 RS09420
gene id: 1302659:I858_RS09420
uniprot id: A0A1B1S4Y6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS02210
gene id: 1302659:I858_RS02210
uniprot id: A0A1B1RZX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

1302659:I858 RS14370
gene id: 1302659:I858_RS14370
uniprot id: A0A1B1S257
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1302659:I858 RS05595
gene id: 1302659:I858_RS05595
uniprot id: A0A1B1RY75
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS11180
gene id: 1302659:I858_RS11180
uniprot id: A0A1B1S3X5
names: Function
names: Similarity
messages: Belongs to the BshC family.
messages: Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.

1302659:I858 RS01815
gene id: 1302659:I858_RS01815
uniprot id: A0A1B1S031
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS01665
gene id: 1302659:I858_RS01665
uniprot id: A0A1B1S0A0
names: Cofactor
messages: Binds 1 FAD per subunit.

1302659:I858 RS05050
gene id: 1302659:I858_RS05050
uniprot id: A0A1B1RYG5
names: Similarity
messages: Belongs to the universal stress protein A family.

1302659:I858 RS13055
gene id: 1302659:I858_RS13055
uniprot id: A0A1B1S2W8
names: Similarity
messages: Belongs to the acyltransferase 3 family.

1302659:I858 RS04645
gene id: 1302659:I858_RS04645
uniprot id: A0A1B1RYN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS13550
gene id: 1302659:I858_RS13550
uniprot id: A0A1B1S2M7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1302659:I858 RS07185
gene id: 1302659:I858_RS07185
uniprot id: A0A1B1RXD3
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

1302659:I858 RS10035
gene id: 1302659:I858_RS10035
uniprot id: A0A1B1S4K0
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS08195
gene id: 1302659:I858_RS08195
uniprot id: A0A1B1S5L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1302659:I858 RS16295
gene id: 1302659:I858_RS16295
uniprot id: A0A1B1S140
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1302659:I858 RS13960
gene id: 1302659:I858_RS13960
uniprot id: A0A1B1S2E0
names: Similarity
messages: Belongs to the EamA transporter family.

1302659:I858 RS00580
gene id: 1302659:I858_RS00580
uniprot id: A0A1B1S0U4
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1302659:I858 RS13850
gene id: 1302659:I858_RS13850
uniprot id: A0A1B1S2G8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1302659:I858 RS01685
gene id: 1302659:I858_RS01685
uniprot id: A0A1B1S081
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

1302659:I858 RS06440
gene id: 1302659:I858_RS06440
uniprot id: A0A1B1RXT3
names: Similarity
messages: Belongs to the universal stress protein A family.

1302659:I858 RS12575
gene id: 1302659:I858_RS12575
uniprot id: A0A1B1S353
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1302659:I858 RS03330
gene id: 1302659:I858_RS03330
uniprot id: A0A1B1RZC4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1302659:I858 RS07290
gene id: 1302659:I858_RS07290
uniprot id: A0A1B1RXB4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1302659:I858 RS11105
gene id: 1302659:I858_RS11105
uniprot id: A0A1B1S3Y5
names: Similarity
messages: Belongs to the YggT family.

1302659:I858 RS10185
gene id: 1302659:I858_RS10185
uniprot id: A0A1B1S4G9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1302659:I858 RS12175
gene id: 1302659:I858_RS12175
uniprot id: A0A1B1S3B1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1302659:I858 RS10395
gene id: 1302659:I858_RS10395
uniprot id: A0A1B1S4D9
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS10655
gene id: 1302659:I858_RS10655
uniprot id: A0A1B1S478
names: Similarity
messages: Belongs to the peptidase M16 family.

1302659:I858 RS03655
gene id: 1302659:I858_RS03655
uniprot id: A0A1B1RZ82
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.
messages: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
messages: The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.

1302659:I858 RS14120
gene id: 1302659:I858_RS14120
uniprot id: A0A1B1S2A2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1302659:I858 RS07370
gene id: 1302659:I858_RS07370
uniprot id: A0A1B1RX97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1302659:I858 RS04135
gene id: 1302659:I858_RS04135
uniprot id: A0A1B1RYW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

1302659:I858 RS06725
gene id: 1302659:I858_RS06725
uniprot id: A0A1B1RXL8
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1302659:I858 RS02885
gene id: 1302659:I858_RS02885
uniprot id: A0A1B1RZM3
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.
messages: In the N-terminal section; belongs to the MsrA Met sulfoxide reductase family.

1302659:I858 RS11040
gene id: 1302659:I858_RS11040
uniprot id: A0A1B1S410
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
messages: Cytoplasm
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.

1302659:I858 RS12420
gene id: 1302659:I858_RS12420
uniprot id: A0A1B1S3C6
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1302659:I858 RS01535
gene id: 1302659:I858_RS01535
uniprot id: A0A1B1S0B2
names: Similarity
messages: Belongs to the peptidase S8 family.

1302659:I858 RS12610
gene id: 1302659:I858_RS12610
uniprot id: A0A1B1S347
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1302659:I858 RS01695
gene id: 1302659:I858_RS01695
uniprot id: A0A1B1S077
names: Similarity
messages: Belongs to the SCO1/2 family.

1302659:I858 RS09765
gene id: 1302659:I858_RS09765
uniprot id: A0A1B1S4P0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

1302659:I858 RS13675
gene id: 1302659:I858_RS13675
uniprot id: A0A1B1S2M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS03600
gene id: 1302659:I858_RS03600
uniprot id: A0A1B1RZ76
names: Similarity
messages: Belongs to the glutamate synthase family.

1302659:I858 RS05180
gene id: 1302659:I858_RS05180
uniprot id: A0A1B1RYF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.

1302659:I858 RS04280
gene id: 1302659:I858_RS04280
uniprot id: A0A1B1RYV5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS13600
gene id: 1302659:I858_RS13600
uniprot id: A0A1B1S2L6
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the octanoyltransferase LipL family.
messages: Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes.
messages: The reaction proceeds via a thioester-linked acyl-enzyme intermediate.

1302659:I858 RS07915
gene id: 1302659:I858_RS07915
uniprot id: A0A1B1S5Q2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1302659:I858 RS08860
gene id: 1302659:I858_RS08860
uniprot id: A0A1B1S577
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1302659:I858 RS07410
gene id: 1302659:I858_RS07410
uniprot id: A0A1B1RX86
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1302659:I858 RS04380
gene id: 1302659:I858_RS04380
uniprot id: A0A1B1RYS7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1302659:I858 RS09620
gene id: 1302659:I858_RS09620
uniprot id: A0A1B1S4T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1302659:I858 RS10745
gene id: 1302659:I858_RS10745
uniprot id: A0A1B1S457
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1302659:I858 RS12225
gene id: 1302659:I858_RS12225
uniprot id: A0A1B1S3A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS08850
gene id: 1302659:I858_RS08850
uniprot id: A0A1B1S578
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1302659:I858 RS11800
gene id: 1302659:I858_RS11800
uniprot id: A0A1B1S3H9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1302659:I858 RS04770
gene id: 1302659:I858_RS04770
uniprot id: A0A1B1RYJ2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1302659:I858 RS07300
gene id: 1302659:I858_RS07300
uniprot id: A0A1B1RXB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1302659:I858 RS07220
gene id: 1302659:I858_RS07220
uniprot id: A0A1B1RXB8
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1302659:I858 RS09720
gene id: 1302659:I858_RS09720
uniprot id: A0A1B1S4R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS03105
gene id: 1302659:I858_RS03105
uniprot id: A0A1B1RZJ3
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1302659:I858 RS16045
gene id: 1302659:I858_RS16045
uniprot id: A0A1B1S192
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS11395
gene id: 1302659:I858_RS11395
uniprot id: A0A1B1S3Q6
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1302659:I858 RS02905
gene id: 1302659:I858_RS02905
uniprot id: A0A1B1RZM2
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS07745
gene id: 1302659:I858_RS07745
uniprot id: A0A1B1RX26
names: Similarity
messages: Belongs to the MoaD family.

1302659:I858 RS16220
gene id: 1302659:I858_RS16220
uniprot id: A0A1B1S184
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

1302659:I858 RS02790
gene id: 1302659:I858_RS02790
uniprot id: A0A1B1RZK7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1302659:I858 RS12800
gene id: 1302659:I858_RS12800
uniprot id: A0A1B1S310
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1302659:I858 RS11830
gene id: 1302659:I858_RS11830
uniprot id: A0A1B1S3J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1302659:I858 RS10145
gene id: 1302659:I858_RS10145
uniprot id: A0A1B1S4J0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1302659:I858 RS12330
gene id: 1302659:I858_RS12330
uniprot id: A0A1B1S3A0
names: Similarity
messages: Belongs to the PemK/MazF family.

1302659:I858 RS00650
gene id: 1302659:I858_RS00650
uniprot id: A0A1B1S0W2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1302659:I858 RS00005
gene id: 1302659:I858_RS00005
uniprot id: A0A1B1S156
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1302659:I858 RS13140
gene id: 1302659:I858_RS13140
uniprot id: A0A1B1S2V0
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS03170
gene id: 1302659:I858_RS03170
uniprot id: A0A1B1RZG8
names: Similarity
messages: Belongs to the YoeB family.

1302659:I858 RS07305
gene id: 1302659:I858_RS07305
uniprot id: A0A1B1RXB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1302659:I858 RS04420
gene id: 1302659:I858_RS04420
uniprot id: A0A1B1RYT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1302659:I858 RS15615
gene id: 1302659:I858_RS15615
uniprot id: A0A1B1S1J3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

1302659:I858 RS08825
gene id: 1302659:I858_RS08825
uniprot id: A0A1B1S5B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1302659:I858 RS10765
gene id: 1302659:I858_RS10765
uniprot id: A0A1B1S450
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.

1302659:I858 RS14490
gene id: 1302659:I858_RS14490
uniprot id: A0A1B1S231
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS07175
gene id: 1302659:I858_RS07175
uniprot id: A0A1B1RXC8
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1302659:I858 RS10710
gene id: 1302659:I858_RS10710
uniprot id: A0A1B1S475
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1302659:I858 RS14005
gene id: 1302659:I858_RS14005
uniprot id: A0A1B1S2D0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1302659:I858 RS07505
gene id: 1302659:I858_RS07505
uniprot id: A0A1B1RX71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

1302659:I858 RS12995
gene id: 1302659:I858_RS12995
uniprot id: A0A1B1S2X6
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1302659:I858 RS14875
gene id: 1302659:I858_RS14875
uniprot id: A0A1B1S1Y3
names: Similarity
messages: Belongs to the ThiD family.

1302659:I858 RS09990
gene id: 1302659:I858_RS09990
uniprot id: A0A1B1S4L6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1302659:I858 RS14775
gene id: 1302659:I858_RS14775
uniprot id: A0A1B1S201
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DbpA subfamily.
messages: Contains an N-terminal domain that binds non-specifically to RNA and a C-terminal domain that binds specifically and tightly to hairpin 92 of 23S rRNA.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes.

1302659:I858 RS02320
gene id: 1302659:I858_RS02320
uniprot id: A0A1B1RZW8
names: Similarity
messages: Belongs to the TrpC family.

1302659:I858 RS14575
gene id: 1302659:I858_RS14575
uniprot id: A0A1B1S220
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1302659:I858 RS13325
gene id: 1302659:I858_RS13325
uniprot id: A0A1B1S2Q1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1302659:I858 RS14665
gene id: 1302659:I858_RS14665
uniprot id: A0A1B1S200
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1302659:I858 RS07035
gene id: 1302659:I858_RS07035
uniprot id: A0A1B1RXF1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1302659:I858 RS09705
gene id: 1302659:I858_RS09705
uniprot id: A0A1B1S4V9
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1302659:I858 RS16240
gene id: 1302659:I858_RS16240
uniprot id: A0A1B1S143
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1302659:I858 RS05680
gene id: 1302659:I858_RS05680
uniprot id: A0A1B1RY35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS12075
gene id: 1302659:I858_RS12075
uniprot id: A0A1B1S3D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1302659:I858 RS10830
gene id: 1302659:I858_RS10830
uniprot id: A0A1B1S448
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1302659:I858 RS05685
gene id: 1302659:I858_RS05685
uniprot id: A0A1B1RY37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

1302659:I858 RS15390
gene id: 1302659:I858_RS15390
uniprot id: A0A1B1S1N2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1302659:I858 RS10855
gene id: 1302659:I858_RS10855
uniprot id: A0A1B1S442
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

1302659:I858 RS16015
gene id: 1302659:I858_RS16015
uniprot id: A0A1B1S1C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1302659:I858 RS10825
gene id: 1302659:I858_RS10825
uniprot id: A0A1B1S489
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1302659:I858 RS00185
gene id: 1302659:I858_RS00185
uniprot id: A0A1B1S101
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS08095
gene id: 1302659:I858_RS08095
uniprot id: A0A1B1S5M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1302659:I858 RS07000
gene id: 1302659:I858_RS07000
uniprot id: A0A1B1RXH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1302659:I858 RS15785
gene id: 1302659:I858_RS15785
uniprot id: A0A1B1S1E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1302659:I858 RS10860
gene id: 1302659:I858_RS10860
uniprot id: A0A1B1S445
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1302659:I858 RS04405
gene id: 1302659:I858_RS04405
uniprot id: A0A1B1RYT7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1302659:I858 RS10795
gene id: 1302659:I858_RS10795
uniprot id: A0A1B1S447
names: Similarity
messages: Belongs to the DprA/Smf family.

1302659:I858 RS06500
gene id: 1302659:I858_RS06500
uniprot id: A0A1B1RXS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1302659:I858 RS02315
gene id: 1302659:I858_RS02315
uniprot id: A0A1B1RZW3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS00325
gene id: 1302659:I858_RS00325
uniprot id: A0A1B1S0Z4
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1302659:I858 RS04745
gene id: 1302659:I858_RS04745
uniprot id: A0A1B1RYL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS10665
gene id: 1302659:I858_RS10665
uniprot id: A0A1B1S471
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1302659:I858 RS11860
gene id: 1302659:I858_RS11860
uniprot id: A0A1B1S3J2
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1302659:I858 RS15870
gene id: 1302659:I858_RS15870
uniprot id: A0A1B1S1D0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1302659:I858 RS01310
gene id: 1302659:I858_RS01310
uniprot id: A0A1B1S0D8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1302659:I858 RS10260
gene id: 1302659:I858_RS10260
uniprot id: A0A1B1S4F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

1302659:I858 RS04580
gene id: 1302659:I858_RS04580
uniprot id: A0A1B1RYN6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1302659:I858 RS10660
gene id: 1302659:I858_RS10660
uniprot id: A0A1B1S485
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1302659:I858 RS08715
gene id: 1302659:I858_RS08715
uniprot id: A0A1B1S5A8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1302659:I858 RS01400
gene id: 1302659:I858_RS01400
uniprot id: A0A1B1S0E1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1302659:I858 RS01345
gene id: 1302659:I858_RS01345
uniprot id: A0A1B1S0E6
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS04060
gene id: 1302659:I858_RS04060
uniprot id: A0A1B1RYZ2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1302659:I858 RS08950
gene id: 1302659:I858_RS08950
uniprot id: A0A1B1S559
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. CshB subfamily.
messages: Cytoplasm
messages: Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures.

1302659:I858 RS06970
gene id: 1302659:I858_RS06970
uniprot id: A0A1B1RXH3
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

1302659:I858 RS08115
gene id: 1302659:I858_RS08115
uniprot id: A0A1B1S5L4
names: Similarity
messages: Belongs to the FBPase class 3 family.

1302659:I858 RS10165
gene id: 1302659:I858_RS10165
uniprot id: A0A1B1S4G7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1302659:I858 RS14835
gene id: 1302659:I858_RS14835
uniprot id: A0A1B1S1W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS07210
gene id: 1302659:I858_RS07210
uniprot id: A0A1B1RXD2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS06445
gene id: 1302659:I858_RS06445
uniprot id: A0A1B1RXS9
names: Similarity
messages: Belongs to the YjdM family.

1302659:I858 RS00690
gene id: 1302659:I858_RS00690
uniprot id: A0A1B1S0S1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1302659:I858 RS04260
gene id: 1302659:I858_RS04260
uniprot id: A0A1B1RYU7
names: Similarity
messages: Belongs to the peptidase S8 family.

1302659:I858 RS03630
gene id: 1302659:I858_RS03630
uniprot id: A0A1B1RZ90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS14090
gene id: 1302659:I858_RS14090
uniprot id: A0A1B1S2B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS06770
gene id: 1302659:I858_RS06770
uniprot id: A0A1B1RXL2
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1302659:I858 RS11360
gene id: 1302659:I858_RS11360
uniprot id: A0A1B1S3U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1302659:I858 RS10385
gene id: 1302659:I858_RS10385
uniprot id: A0A1B1S4C8
names: Cofactor
names: Function
names: PTM
names: Subcellular Location Annotation
messages: Autophosphorylated.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1302659:I858 RS05665
gene id: 1302659:I858_RS05665
uniprot id: A0A1B1RY43
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1302659:I858 RS00635
gene id: 1302659:I858_RS00635
uniprot id: A0A1B1S0U3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1302659:I858 RS10585
gene id: 1302659:I858_RS10585
uniprot id: A0A1B1S474
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1302659:I858 RS10670
gene id: 1302659:I858_RS10670
uniprot id: A0A1B1S466
names: Similarity
messages: Belongs to the ribF family.

1302659:I858 RS12570
gene id: 1302659:I858_RS12570
uniprot id: A0A1B1S395
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1302659:I858 RS14075
gene id: 1302659:I858_RS14075
uniprot id: A0A1B1S2E6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1302659:I858 RS11095
gene id: 1302659:I858_RS11095
uniprot id: A0A1B1S3X0
names: Subcellular Location Annotation
messages: Cytoplasm

1302659:I858 RS01275
gene id: 1302659:I858_RS01275
uniprot id: A0A1B1S0H8
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS01580
gene id: 1302659:I858_RS01580
uniprot id: A0A1B1S0D4
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1302659:I858 RS08975
gene id: 1302659:I858_RS08975
uniprot id: A0A1B1S542
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1302659:I858 RS00575
gene id: 1302659:I858_RS00575
uniprot id: A0A1B1S0W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1302659:I858 RS04480
gene id: 1302659:I858_RS04480
uniprot id: A0A1B1RYQ6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1302659:I858 RS06905
gene id: 1302659:I858_RS06905
uniprot id: A0A1B1RXI6
names: Similarity
messages: Belongs to the GSP E family.

1302659:I858 RS05625
gene id: 1302659:I858_RS05625
uniprot id: A0A1B1RY45
names: Similarity
messages: Belongs to the UPF0349 family.

1302659:I858 RS04600
gene id: 1302659:I858_RS04600
uniprot id: A0A1B1RYP3
names: Similarity
messages: Belongs to the DinB family.

1302659:I858 RS08780
gene id: 1302659:I858_RS08780
uniprot id: A0A1B1S595
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1302659:I858 RS07155
gene id: 1302659:I858_RS07155
uniprot id: A0A1B1RXD6
names: Similarity
messages: Belongs to the UPF0473 family.

1302659:I858 RS09450
gene id: 1302659:I858_RS09450
uniprot id: A0A1B1S509
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

1302659:I858 RS12145
gene id: 1302659:I858_RS12145
uniprot id: A0A1B1S3E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1302659:I858 RS13935
gene id: 1302659:I858_RS13935
uniprot id: A0A1B1S2D4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1302659:I858 RS15140
gene id: 1302659:I858_RS15140
uniprot id: A0A1B1S1R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1302659:I858 RS15285
gene id: 1302659:I858_RS15285
uniprot id: A0A1B1S1M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS06845
gene id: 1302659:I858_RS06845
uniprot id: A0A1B1RXK5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1302659:I858 RS02400
gene id: 1302659:I858_RS02400
uniprot id: A0A1B1RZX2
names: Similarity
messages: Belongs to the universal stress protein A family.

1302659:I858 RS13950
gene id: 1302659:I858_RS13950
uniprot id: A0A1B1S2E9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1302659:I858 RS12465
gene id: 1302659:I858_RS12465
uniprot id: A0A1B1S376
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1302659:I858 RS02280
gene id: 1302659:I858_RS02280
uniprot id: A0A1B1RZU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS13390
gene id: 1302659:I858_RS13390
uniprot id: A0A1B1S2Q7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1302659:I858 RS12180
gene id: 1302659:I858_RS12180
uniprot id: A0A1B1S3C9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1302659:I858 RS13470
gene id: 1302659:I858_RS13470
uniprot id: A0A1B1S2R5
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1302659:I858 RS02480
gene id: 1302659:I858_RS02480
uniprot id: A0A1B1RZR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

1302659:I858 RS09550
gene id: 1302659:I858_RS09550
uniprot id: A0A1B1S4Y9
names: Subcellular Location Annotation
messages: Cytoplasm

1302659:I858 RS11650
gene id: 1302659:I858_RS11650
uniprot id: A0A1B1S3M7
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS10940
gene id: 1302659:I858_RS10940
uniprot id: A0A1B1S3Z8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1302659:I858 RS11980
gene id: 1302659:I858_RS11980
uniprot id: A0A1B1S3H3
names: PTM
messages: Binds 1 heme c group covalently per subunit.

1302659:I858 RS03125
gene id: 1302659:I858_RS03125
uniprot id: A0A1B1RZG2
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS03130
gene id: 1302659:I858_RS03130
uniprot id: A0A1B1RZG7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1302659:I858 RS11440
gene id: 1302659:I858_RS11440
uniprot id: A0A1B1S3S4
names: Function
names: Similarity
names: Subunit
messages: A non-essential component of RNA polymerase (RNAP).
messages: Belongs to the RNA polymerase subunit epsilon family.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunit. The core is associated with a delta subunit, and at least one of epsilon or omega. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1302659:I858 RS01045
gene id: 1302659:I858_RS01045
uniprot id: A0A1B1S0K9
names: Similarity
messages: Belongs to the bacterial flagellin family.

1302659:I858 RS12475
gene id: 1302659:I858_RS12475
uniprot id: A0A1B1S374
names: Similarity
messages: Belongs to the YciI family.

1302659:I858 RS15215
gene id: 1302659:I858_RS15215
uniprot id: A0A1B1S1N0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1302659:I858 RS11925
gene id: 1302659:I858_RS11925
uniprot id: A0A1B1S3I3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

1302659:I858 RS14725
gene id: 1302659:I858_RS14725
uniprot id: A0A1B1S212
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1302659:I858 RS00725
gene id: 1302659:I858_RS00725
uniprot id: A0A1B1S0T9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1302659:I858 RS15175
gene id: 1302659:I858_RS15175
uniprot id: A0A1B1S1Q2
names: Subcellular Location Annotation
messages: Membrane

1302659:I858 RS10995
gene id: 1302659:I858_RS10995
uniprot id: A0A1B1S406
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS05330
gene id: 1302659:I858_RS05330
uniprot id: A0A1B1RYC5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1302659:I858 RS13425
gene id: 1302659:I858_RS13425
uniprot id: A0A1B1S2N3
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1302659:I858 RS10270
gene id: 1302659:I858_RS10270
uniprot id: A0A1B1S4K2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1302659:I858 RS09425
gene id: 1302659:I858_RS09425
uniprot id: A0A1B1S4Y5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS07770
gene id: 1302659:I858_RS07770
uniprot id: A0A1B1RX19
names: Similarity
messages: Belongs to the CdaR family.

1302659:I858 RS05905
gene id: 1302659:I858_RS05905
uniprot id: A0A1B1RY21
names: Similarity
messages: Belongs to the isochorismate synthase family.

1302659:I858 RS08700
gene id: 1302659:I858_RS08700
uniprot id: A0A1B1S5B3
names: Similarity
messages: Belongs to the TlyA family.

1302659:I858 RS01525
gene id: 1302659:I858_RS01525
uniprot id: A0A1B1S0D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1302659:I858 RS05970
gene id: 1302659:I858_RS05970
uniprot id: A0A1B1RY26
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS08130
gene id: 1302659:I858_RS08130
uniprot id: A0A1B1S5M2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1302659:I858 RS11810
gene id: 1302659:I858_RS11810
uniprot id: A0A1B1S3K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1302659:I858 RS01235
gene id: 1302659:I858_RS01235
uniprot id: A0A1B1S0H4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1302659:I858 RS13980
gene id: 1302659:I858_RS13980
uniprot id: A0A1B1S2C9
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Consists of two distinct domains; an N-terminal heme-containing oxygen-binding domain and a C-terminal reductase domain with binding sites for FAD and NAD(P)H.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1302659:I858 RS04960
gene id: 1302659:I858_RS04960
uniprot id: A0A1B1RYJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane